Ethical Conduct of Research

The National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) at the National Institutes of Health (NIH) appointed an independent Observational Study Monitoring Board (OSMB) to oversee the Osteoarthritis Initiative (OAI) study from 2002 to 2014.

Responsibilities of the board included:

  • evaluating the study progress;
  • protecting the safety of study participants;
  • and considering ethical and other external factors that could impact participant safety.

The OSMB was disbanded upon study completion and monitoring obligations were fulfilled.