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1 Numbers reported are subjects by age
New Trial
New Project

Format should be in the following format: Activity Code, Institute Abbreviation, and Serial Number. Grant Type, Support Year, and Suffix should be excluded. For example, grant 1R01MH123456-01A1 should be entered R01MH123456

Please select an experiment type below

Collection - Use Existing Experiment
To associate an experiment to the current collection, just select an axperiment from the table below then click the associate experiment button to persist your changes (saving the collection is not required). Note that once an experiment has been associated to two or more collections, the experiment will not longer be editable.

The table search feature is case insensitive and targets the experiment id, experiment name and experiment type columns. The experiment id is searched only when the search term entered is a number, and filtered using a startsWith comparison. When the search term is not numeric the experiment name is used to filter the results.
SelectExperiment IdExperiment NameExperiment Type
Created On
24HI-NGS_R1Omics02/16/2011
475MB1-10 (CHOP)Omics06/07/2016
490Discovery and CRISPR validation of genetic factors associated with antipsychotic-induced weight gain and cardiometabolic riskOmics07/07/2016
501PharmacoBOLD Resting StatefMRI07/27/2016
506PVPREFOmics08/05/2016
509ABC-CT Resting v2EEG08/18/2016
13Comparison of FI expression in Autistic and Neurotypical Homo SapiensOmics12/28/2010
18AGRE/Broad Affymetrix 5.0 Genotype ExperimentOmics01/06/2011
22Stitching PCR SequencingOmics02/14/2011
26ASD_MethylationOmics03/01/2011
29Microarray family 03 (father, mother, sibling)Omics03/24/2011
37Standard paired-end sequencing of BCRsOmics04/19/2011
38Illumina Mate-Pair BCR sequencingOmics04/19/2011
39Custom Jumping LibrariesOmics04/19/2011
40Custom CapBPOmics04/19/2011
41ImmunofluorescenceOmics05/11/2011
43Autism brain sample genotyping, IlluminaOmics05/16/2011
47ARRA Autism Sequencing Collaboration at Baylor. SOLiD 4 SystemOmics08/01/2011
53AGRE Omni1-quadOmics10/11/2011
59AGP genotypingOmics04/03/2012
60Ultradeep 454 sequencing of synaptic genes from postmortem cerebella of individuals with ASD and neurotypical controlsOmics06/23/2012
63Microemulsion PCR and Targeted Resequencing for Variant Detection in ASDOmics07/20/2012
76Whole Genome Sequencing in Autism FamiliesOmics01/03/2013
519RestingfMRI11/08/2016
90Genotyped IAN SamplesOmics07/09/2013
91NJLAGS Axiom Genotyping ArrayOmics07/16/2013
93AGP genotyping (CNV)Omics09/06/2013
106Longitudinal Sleep Study. H20 200. Channel set 2EEG11/07/2013
107Longitudinal Sleep Study. H20 200. Channel set 3EEG11/07/2013
108Longitudinal Sleep Study. AURA 200EEG11/07/2013
105Longitudinal Sleep Study. H20 200. Channel set 1EEG11/07/2013
109Longitudinal Sleep Study. AURA 400EEG11/07/2013
116Gene Expression Analysis WG-6Omics01/07/2014
131Jeste Lab UCLA ACEii: Charlie Brown and Sesame Street - Project 1Eye Tracking02/27/2014
132Jeste Lab UCLA ACEii: Animacy - Project 1Eye Tracking02/27/2014
133Jeste Lab UCLA ACEii: Mom Stranger - Project 2Eye Tracking02/27/2014
134Jeste Lab UCLA ACEii: Face Emotion - Project 3Eye Tracking02/27/2014
145AGRE/FMR1_Illumina.JHUOmics04/14/2014
146AGRE/MECP2_Sanger.JHUOmics04/14/2014
147AGRE/MECP2_Junior.JHUOmics04/14/2014
151Candidate Gene Identification in familial AutismOmics06/09/2014
152NJLAGS Whole Genome SequencingOmics07/01/2014
154Math Autism Study - Vinod MenonfMRI07/15/2014
155RestingfMRI07/25/2014
156SpeechfMRI07/25/2014
159EmotionfMRI07/25/2014
160syllable contrastEEG07/29/2014
167School-age naturalistic stimuliEye Tracking09/19/2014
44AGRE/Broad Affymetrix 5.0 Genotype ExperimentOmics06/27/2011
45Exome Sequencing of 20 Sporadic Cases of Autism Spectrum DisorderOmics07/15/2011
Collection - Add Experiment
Add Supporting Documentation
Select File

To add an existing Data Structure, enter its title in the search bar. If you need to request changes, select the indicator "No, it requires changes to meet research needs" after selecting the Structure, and upload the file with the request changes specific to the selected Data Structure. Your file should follow the Request Changes Procedure. If the Data Structure does not exist, select "Request New Data Structure" and upload the appropriate zip file.

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Please confirm that you will not be enrolling any more subjects and that all raw data has been collected and submitted.

Collection Updated

Your Collection is now in Data Analysis phase and exempt from biannual submissions. Analyzed data is still expected prior to publication or no later than the project end date.

[CMS] Attention
[CMS] Please confirm that you will not be enrolling any more subjects and that all raw data has been collected and submitted.
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[CMS]

Unable to change collection phase where targeted enrollment is less than 90%

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You have requested to move the sharing dates for the following assessments:
Data Expected Item Original Sharing Date New Sharing Date

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Collection Summary Collection Charts
Collection Title Collection Investigators Collection Description
Phenomenology and Classification of Schizophrenia (Iowa Longitudinal Study)
Nancy Andreasen 
This study is currently following first-episode patients, some of whom have been followed for as long as 15 years. The study emphasizes understanding the phenomenology of schizophrenia by examining the lifetime trajectory of the illness and its long-term outcome. Since the disorder is characterized by a prolonged lifetime course, longitudinal study of a large group of informative patients is one of the most powerful strategies for examining measures that will illuminate its mechanisms or refine the definition of its phenotype. This study examines 4 domains of variables: Symptoms, psychosocial function, brain morphology as measured by morphometric magnetic resonance imaging, and cognition as measured by both standard neuropsychological tests and a group of experimental tests. We have found that, although symptoms stabilize relatively quickly after initial onset in the majority of patients, the other domains tend to worsen throughout the first decade after onset. This suggests that the disorder may have a worse prognosis, despite adequate treatment, than originally anticipated. We also will divide the patients into groups based levels of recovery and determine the predictors of recovery group. In order to understand the long-term outcome of schizophrenia at the clinical, neural, and cognitive levels, it is important that we continue to study this large group of patients longitudinally on into the second decade of the illness so that we can examine the interrelationships between these four domains and determine whether the downward trends persist or stabilize.
NIMH Data Archive
10/24/2014
Funding Completed
Close Out
No
$7,176,166.00
275
10.15154/z32v-tv80
Loading Chart...
NIH - Extramural None

CASH.pdf Methods CASH Assessment Qualified Researchers
PSYCH_UP_INSTRUMENT3.pdf Methods PSYCH UP Assessment Qualified Researchers
PSYCH_INSTRUMENT_3_0.pdf Methods PSYCH Assessment Qualified Researchers


R01MH031593-01 PHENOMENOLOGY AND CLASSIFICATION OF SCHIZOPHRENIA 07/01/1995 06/30/1999 06/30/2004 Not Reported Not Reported UNIVERSITY OF IOWA $2,682,773.00
R01MH040856-01 BRAIN IMAGING IN THE MAJOR PSYCHOSES 08/01/1995 03/31/2004 01/31/2010 320 286 UNIVERSITY OF IOWA $4,493,393.00

helpcenter.collection.general-tab

NDA Help Center

Collection - General Tab

Fields available for edit on the top portion of the page include:

  • Collection Title
  • Investigators
  • Collection Description
  • Collection Phase
  • Funding Source
  • Clinical Trials

Collection Phase: The current status of a research project submitting data to an NDA Collection, based on the timing of the award and/or the data that have been submitted.

  • Pre-Enrollment: The default entry made when the NDA Collection is created.
  • Enrolling: Data have been submitted to the NDA Collection or the NDA Data Expected initial submission date has been reached for at least one data structure category in the NDA Collection.
  • Data Analysis: Subject level data collection for the research project is completed and has been submitted to the NDA Collection. The NDA Collection owner or the NDA Help Desk may set this phase when they’ve confirmed data submission is complete and submitted subject counts match at least 90% of the target enrollment numbers in the NDA Data Expected. Data submission reminders will be turned off for the NDA Collection.
  • Funding Completed: The NIH grant award (or awards) associated with the NDA Collection has reached its end date. NDA Collections in Funding Completed phase are assigned a subphase to indicate the status of data submission.
    • The Data Expected Subphase indicates that NDA expects more data will be submitted
    • The Closeout Subphase indicates the data submission is complete.
    • The Sharing Not Met Subphase indicates that data submission was not completed as expected.

Blinded Clinical Trial Status:

  • This status is set by a Collection Owner and indicates the research project is a double blinded clinical trial. When selected, the public view of Data Expected will show the Data Expected items and the Submission Dates, but the targeted enrollment and subjects submitted counts will not be displayed.
  • Targeted enrollment and subjects submitted counts are visible only to NDA Administrators and to the NDA Collection or as the NDA Collection Owner.
  • When an NDA Collection that is flagged Blinded Clinical Trial reaches the maximum data sharing date for that Data Repository (see https://nda.nih.gov/nda/sharing-regimen.html), the embargo on Data Expected information is released.

Funding Source

The organization(s) responsible for providing the funding is listed here.

Supporting Documentation

Users with Submission privileges, as well as Collection Owners, Program Officers, and those with Administrator privileges, may upload and attach supporting documentation. By default, supporting documentation is shared to the general public, however, the option is also available to limit this information to qualified researchers only.

Grant Information

Identifiable details are displayed about the Project of which the Collection was derived from. You may click in the Project Number to view a full report of the Project captured by the NIH.

Clinical Trials

Any data that is collected to support or further the research of clinical studies will be available here. Collection Owners and those with Administrator privileges may add new clinical trials.

Frequently Asked Questions

  • How does the NIMH Data Archive (NDA) determine which Permission Group data are submitted into?
    During Collection creation, NDA staff determine the appropriate Permission Group based on the type of data to be submitted, the type of access that will be available to data access users, and the information provided by the Program Officer during grant award.
  • How do I know when a NDA Collection has been created?
    When a Collection is created by NDA staff, an email notification will automatically be sent to the PI(s) of the grant(s) associated with the Collection to notify them.
  • Is a single grant number ever associated with more than one Collection?
    The NDA system does not allow for a single grant to be associated with more than one Collection; therefore, a single grant will not be listed in the Grant Information section of a Collection for more than one Collection.
  • Why is there sometimes more than one grant included in a Collection?
    In general, each Collection is associated with only one grant; however, multiple grants may be associated if the grant has multiple competing segments for the same grant number or if multiple different grants are all working on the same project and it makes sense to hold the data in one Collection (e.g., Cooperative Agreements).

Glossary

  • Administrator Privilege
    A privilege provided to a user associated with an NDA Collection or NDA Study whereby that user can perform a full range of actions including providing privileges to other users.
  • Collection Owner
    Generally, the Collection Owner is the contact PI listed on a grant. Only one NDA user is listed as the Collection owner. Most automated emails are primarily sent to the Collection Owner.
  • Collection Phase
    The Collection Phase provides information on data submission as opposed to grant/project completion so while the Collection phase and grant/project phase may be closely related they are often different. Collection users with Administrative Privileges are encouraged to edit the Collection Phase. The Program Officer as listed in eRA (for NIH funded grants) may also edit this field. Changes must be saved by clicking the Save button at the bottom of the page. This field is sortable alphabetically in ascending or descending order. Collection Phase options include:
    • Pre-Enrollment: A grant/project has started, but has not yet enrolled subjects.
    • Enrolling: A grant/project has begun enrolling subjects. Data submission is likely ongoing at this point.
    • Data Analysis: A grant/project has completed enrolling subjects and has completed all data submissions.
    • Funding Completed: A grant/project has reached the project end date.
  • Collection Title
    An editable field with the title of the Collection, which is often the title of the grant associated with the Collection.
  • Grant
    Provides the grant number(s) for the grant(s) associated with the Collection. The field is a hyperlink so clicking on the Grant number will direct the user to the grant information in the NIH Research Portfolio Online Reporting Tools (RePORT) page.
  • Supporting Documentation
    Various documents and materials to enable efficient use of the data by investigators unfamiliar with the project and may include the research protocol, questionnaires, and study manuals.
  • NIH Research Initiative
    NDA Collections may be organized by scientific similarity into NIH Research Initiatives, to facilitate query tool user experience. NIH Research Initiatives map to one or multiple Funding Opportunity Announcements.
  • Permission Group
    Access to shared record-level data in NDA is provisioned at the level of a Permission Group. NDA Permission Groups consist of one or multiple NDA Collections that contain data with the same subject consents.
  • Planned Enrollment
    Number of human subject participants to be enrolled in an NIH-funded clinical research study. The data is provided in competing applications and annual progress reports.
  • Actual Enrollment
    Number of human subjects enrolled in an NIH-funded clinical research study. The data is provided in annual progress reports.
  • NDA Collection
    A virtual container and organization structure for data and associated documentation from one grant or one large project/consortium. It contains tools for tracking data submission and allows investigators to define a wide array of other elements that provide context for the data, including all general information regarding the data and source project, experimental parameters used to collect any event-based data contained in the Collection, methods, and other supporting documentation. They also allow investigators to link underlying data to an NDA Study, defining populations and subpopulations specific to research aims.
  • Data Use Limitations
    Data Use Limitations (DULs) describe the appropriate secondary use of a dataset and are based on the original informed consent of a research participant. NDA only accepts consent-based data use limitations defined by the NIH Office of Science Policy.
  • Total Subjects Shared
    The total number of unique subjects for whom data have been shared and are available for users with permission to access data.
IDNameCreated DateStatusType
No records found.
helpcenter.collection.experiments-tab

NDA Help Center

Collection - Experiments

The number of Experiments included is displayed in parentheses next to the tab name. You may download all experiments associated with the Collection via the Download button. You may view individual experiments by clicking the Experiment Name and add them to the Filter Cart via the Add to Cart button.

Collection Owners, Program Officers, and users with Submission or Administrative Privileges for the Collection may create or edit an Experiment.

Please note: The creation of an NDA Experiment does not necessarily mean that data collected, according to the defined Experiment, has been submitted or shared.

Frequently Asked Questions

  • Can an Experiment be associated with more than one Collection?

    Yes -see the “Copy” button in the bottom left when viewing an experiment. There are two actions that can be performed via this button:

    1. Copy the experiment with intent for modifications.
    2. Associate the experiment to the collection. No modifications can be made to the experiment.

Glossary

  • Experiment Status
    An Experiment must be Approved before data using the associated Experiment_ID may be uploaded.
  • Experiment ID
    The ID number automatically generated by NDA which must be included in the appropriate file when uploading data to link the Experiment Definition to the subject record.
Comprehensive Assessment of Symptoms and History Clinical Assessments 150
Image Imaging 267
PSYCH Instrument Clinical Assessments 149
PSYCH-up Instrument Clinical Assessments 145
Research Subject Clinical Assessments 275
Scales for the Assessment of Positive/Negative Symptoms Clinical Assessments 60
WAIS-R Clinical Assessments 163
helpcenter.collection.shared-data-tab

NDA Help Center

Collection - Shared Data

This tab provides a quick overview of the Data Structure title, Data Type, and Number of Subjects that are currently Shared for the Collection. The information presented in this tab is automatically generated by NDA and cannot be edited. If no information is visible on this tab, this would indicate the Collection does not have shared data or the data is private.

The shared data is available to other researchers who have permission to access data in the Collection's designated Permission Group(s). Use the Download button to get all shared data from the Collection to the Filter Cart.

Frequently Asked Questions

  • How will I know if another researcher uses data that I shared through the NIMH Data Archive (NDA)?
    To see what data your project have submitted are being used by a study, simply go the Associated Studies tab of your collection. Alternatively, you may review an NDA Study Attribution Report available on the General tab.
  • Can I get a supplement to share data from a completed research project?
    Often it becomes more difficult to organize and format data electronically after the project has been completed and the information needed to create a GUID may not be available; however, you may still contact a program staff member at the appropriate funding institution for more information.
  • Can I get a supplement to share data from a research project that is still ongoing?
    Unlike completed projects where researchers may not have the information needed to create a GUID and/or where the effort needed to organize and format data becomes prohibitive, ongoing projects have more of an opportunity to overcome these challenges. Please contact a program staff member at the appropriate funding institution for more information.

Glossary

  • Data Structure
    A defined organization and group of Data Elements to represent an electronic definition of a measure, assessment, questionnaire, or collection of data points. Data structures that have been defined in the NDA Data Dictionary are available at https://nda.nih.gov/general-query.html?q=query=data-structure
  • Data Type
    A grouping of data by similar characteristics such as Clinical Assessments, Omics, or Neurosignal data.
  • Shared
    The term 'Shared' generally means available to others; however, there are some slightly different meanings based on what is Shared. A Shared NDA Study is viewable and searchable publicly regardless of the user's role or whether the user has an NDA account. A Shared NDA Study does not necessarily mean that data used in the NDA Study have been shared as this is independently determined. Data are shared according the schedule defined in a Collection's Data Expected Tab and/or in accordance with data sharing expectations in the NDA Data Sharing Terms and Conditions. Additionally, Supporting Documentation uploaded to a Collection may be shared independent of whether data are shared.

Collection Owners and those with Collection Administrator permission, may edit a collection. The following is currently available for Edit on this page:

Publications

Publications relevant to NDA data are listed below. Most displayed publications have been associated with the grant within Pubmed. Use the "+ New Publication" button to add new publications. Publications relevant/not relevant to data expected are categorized. Relevant publications are then linked to the underlying data by selecting the Create Study link. Study provides the ability to define cohorts, assign subjects, define outcome measures and lists the study type, data analysis and results. Analyzed data and results are expected in this way.

PubMed IDStudyTitleJournalAuthorsDateStatus
32915832Create StudyPatients on the psychosis spectrum employ an alternate brain network to engage in complex decision-making.PloS oneRamchandran, Kanchna; Fiedorowicz, Jess; Chen, Zhaoying; Bu, Yilin; Bechara, Antoine; Andreasen, Nancy CJanuary 1, 2020Not Determined
25228354Create StudyA genome-wide CNV analysis of schizophrenia reveals a potential role for a multiple-hit model.American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric GeneticsRudd, Danielle S; Axelsen, Michael; Epping, Eric A; Andreasen, Nancy C; Wassink, Thomas HDecember 2014Not Determined
24957354Create StudyEffects of age on white matter integrity and negative symptoms in schizophrenia.Schizophrenia researchBijanki, Kelly Rowe; Hodis, Brendan; Magnotta, Vincent A; Zeien, Eugene; Andreasen, Nancy CJanuary 2015Not Determined
24090512Create StudyEyeblink conditioning in unmedicated schizophrenia patients: a positron emission tomography study.Psychiatry researchParker, Krystal L; Andreasen, Nancy C; Liu, Dawei; Freeman, John H; O'Leary, Daniel SDecember 30, 2013Not Determined
23769814Create StudyProgressive brain changes in schizophrenia related to antipsychotic treatment? A meta-analysis of longitudinal MRI studies.Neuroscience and biobehavioral reviewsFusar-Poli, P; Smieskova, R; Kempton, M J; Ho, B C; Andreasen, N C; Borgwardt, SSeptember 2013Not Determined
23558429Create StudyRelapse duration, treatment intensity, and brain tissue loss in schizophrenia: a prospective longitudinal MRI study.The American journal of psychiatryAndreasen, Nancy C; Liu, Dawei; Ziebell, Steven; Vora, Anvi; Ho, Beng-ChoonJune 2013Not Determined
23108278Create StudyThree-way (N-way) fusion of brain imaging data based on mCCA+jICA and its application to discriminating schizophrenia.NeuroImageSui J, He H, Pearlson GD, Adali T, Kiehl KA, Yu Q, Clark VP, Castro E, White T, Mueller BA, Ho BC, Andreasen NC, Calhoun VDFebruary 1, 2013Not Relevant
22945618Create StudyInfluence of ZNF804a on brain structure volumes and symptom severity in individuals with schizophrenia.Archives of general psychiatryWassink, Thomas H; Epping, Eric A; Rudd, Danielle; Axelsen, Michael; Ziebell, Stephen; Fleming, Frank W; Monson, Eric; Ho, Beng Choon; Andreasen, Nancy CSeptember 2012Not Determined
22850347Create StudyMAPK14 and CNR1 gene variant interactions: effects on brain volume deficits in schizophrenia patients with marijuana misuse.Psychological medicineOnwuameze, O E; Nam, K W; Epping, E A; Wassink, T H; Ziebell, S; Andreasen, N C; Ho, B-CMarch 2013Not Determined
22430943Create StudyEyeblink conditioning in healthy adults: a positron emission tomography study.Cerebellum (London, England)Parker, Krystal L; Andreasen, Nancy C; Liu, Dawei; Freeman, John H; Ponto, Laura L Boles; O'Leary, Daniel SDecember 2012Not Determined
22333522Create StudySex differences in parietal lobe structure and development.Gender medicine. official journal of the Partnership for Gender-Specific Medicine at Columbia UniversitySalinas, Joel; Mills, Elizabeth D; Conrad, Amy L; Koscik, Timothy; Andreasen, Nancy C; Nopoulos, PegFebruary 2012Not Determined
21876540Create StudyStatistical epistasis and progressive brain change in schizophrenia: an approach for examining the relationships between multiple genes.Molecular psychiatryAndreasen, N C; Wilcox, M A; Ho, B-C; Epping, E; Ziebell, S; Zeien, E; Weiss, B; Wassink, TNovember 2012Not Determined
21784414Create StudyProgressive brain change in schizophrenia: a prospective longitudinal study of first-episode schizophrenia.Biological psychiatryAndreasen NC, Nopoulos P, Magnotta V, Pierson R, Ziebell S, Ho BCOctober 1, 2011Not Determined
21420833Create StudyCannabinoid receptor 1 gene polymorphisms and marijuana misuse interactions on white matter and cognitive deficits in schizophrenia.Schizophrenia researchHo, Beng-Choon; Wassink, Thomas H; Ziebell, Steven; Andreasen, Nancy CMay 2011Not Determined
21300943Create StudyLong-term antipsychotic treatment and brain volumes: a longitudinal study of first-episode schizophrenia.Archives of general psychiatryHo, Beng-Choon; Andreasen, Nancy C; Ziebell, Steven; Pierson, Ronald; Magnotta, VincentFebruary 2011Not Determined
21237230Create StudySex-specific variation of MRI-based cortical morphometry in adult healthy volunteers: the effect on cognitive functioning.Progress in neuro-psychopharmacology & biological psychiatryCrespo-Facorro, Benedicto; Roiz-Santiáñez, Roberto; Pérez-Iglesias, Rocío; Mata, Ignacio; Rodríguez-Sánchez, Jose Manuel; Tordesillas-Gutiérrez, Diana; Ortíz-García de la Foz, Victor; Tabarés-Seisdedos, Rafael; Sánchez, Elena; Andreasen, Nancy; Magnotta, Vicent; Vázquez-Barquero, José LuisMarch 30, 2011Not Determined
21134492Create StudyWITHDRAWN: Erratum to "Does function follow form?: Methods to fuse structural and functional brain images show decreased linkage in schizophrenia" [NeuroImage 49 (2010) 2626-2637].NeuroImageMichael, Andrew M; Baum, Stefi A; White, Tonya; Demirci, Oguz; Andreasen, Nancy C; Segall, Judith M; Jung, Rex E; Pearlson, Godfrey; Clark, Vince P; Gollub, Randy L; Schulz, S Charles; Roffman, Joshua L; Lim, Kelvin O; Ho, Beng-Choon; Bockholt, H Jeremy; Calhoun, Vince DMarch 5, 2010Not Determined
20954434Create StudyThe lifetime trajectory of schizophrenia and the concept of neurodevelopment.Dialogues in clinical neuroscienceAndreasen NC2010Not Determined
20942995Create StudyGlobal and regional cortical thinning in first-episode psychosis patients: relationships with clinical and cognitive features.Psychological medicineCrespo-Facorro, B; Roiz-Santiáñez, R; Pérez-Iglesias, R; Rodriguez-Sanchez, J M; Mata, I; Tordesillas-Gutierrez, D; Sanchez, E; Tabarés-Seisdedos, R; Andreasen, N; Magnotta, V; Vázquez-Barquero, J LJuly 2011Not Determined
20600977Create StudyFully automated analysis using BRAINS: AutoWorkup.NeuroImagePierson, Ronald; Johnson, Hans; Harris, Gregory; Keefe, Helen; Paulsen, Jane S; Andreasen, Nancy C; Magnotta, Vincent AJanuary 1, 2011Not Determined
19941961Create StudyHippocampal volume deficits and shape deformities in young biological relatives of schizophrenia probands.NeuroImageHo BC, Magnotta VFebruary 15, 2010Not Determined
19897178Create StudyAntipsychotic dose equivalents and dose-years: a standardized method for comparing exposure to different drugs.Biological psychiatryAndreasen, Nancy C; Pressler, Marcus; Nopoulos, Peg; Miller, Del; Ho, Beng-ChoonFebruary 1, 2010Not Determined
19878956Create StudyCognitive deficits in recent-onset and chronic schizophrenia.Journal of psychiatric researchSponheim, S R; Jung, R E; Seidman, L J; Mesholam-Gately, R I; Manoach, D S; O'Leary, D S; Ho, B C; Andreasen, N C; Lauriello, J; Schulz, S CMay 2010Not Determined
19760675Create StudyG72 influences longitudinal change in frontal lobe volume in schizophrenia.American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric GeneticsHartz, Sarah M; Ho, Beng-Choon; Andreasen, Nancy C; Librant, Amy; Rudd, Danielle; Epping, Eric A; Wassink, Thomas HMarch 5, 2010Not Determined
19538636Create StudyThree-dimensional morphometric analysis of brain shape in nonsyndromic orofacial clefting.Journal of anatomyWeinberg, Seth M; Andreasen, Nancy C; Nopoulos, PegJune 2009Not Determined
18980790Create StudySex differences in parietal lobe morphology: relationship to mental rotation performance.Brain and cognitionKoscik, Tim; O'Leary, Dan; Moser, David J; Andreasen, Nancy C; Nopoulos, PegApril 2009Not Determined
18799289Create StudyBasic helix-loop-helix transcription factor NEUROG1 and schizophrenia: effects on illness susceptibility, MRI brain morphometry and cognitive abilities.Schizophrenia researchHo, Beng-Choon; Epping, Eric; Wang, Kai; Andreasen, Nancy C; Librant, Amy; Wassink, Thomas HDecember 2008Not Determined
18656332Create StudyInvestigating connectivity between the cerebellum and thalamus in schizophrenia using diffusion tensor tractography: a pilot study.Psychiatry researchMagnotta, Vincent A; Adix, Michael L; Caprahan, Arvind; Lim, Kelvin; Gollub, Randy; Andreasen, Nancy CAugust 30, 2008Not Determined
18559406Create StudyTheory of mind and schizophrenia: a positron emission tomography study of medication-free patients.Schizophrenia bulletinAndreasen, Nancy C; Calarge, Chadi A; Calage, Chadi A; O'Leary, Daniel SJuly 2008Not Determined
18473337Create StudyImplications of starvation-induced change in right dorsal anterior cingulate volume in anorexia nervosa.The International journal of eating disordersMcCormick, Laurie M; Keel, Pamela K; Brumm, Michael C; Bowers, Wayne; Swayze, Victor; Andersen, Arnold; Andreasen, NancyNovember 2008Not Determined
18395701Create StudyThe role of the cerebellum in schizophrenia.Biological psychiatryAndreasen, Nancy C; Pierson, RonaldJuly 15, 2008Not Determined
18056245Create StudyAssociation between brain-derived neurotrophic factor Val66Met gene polymorphism and progressive brain volume changes in schizophrenia.The American journal of psychiatryHo, Beng-Choon; Andreasen, Nancy C; Dawson, Jeffrey D; Wassink, Thomas HDecember 2007Not Determined
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16566898Create StudyNeuropsychological performance in first-episode adolescents with schizophrenia: a comparison with first-episode adults and adolescent control subjects.Biological psychiatryWhite T, Ho BC, Ward J, O'Leary D, Andreasen NCSeptember 1, 2006Not Determined
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10484943Create StudyLongitudinal study of cognitive function in first-episode and recent-onset schizophrenia.The American journal of psychiatryGold, S; Arndt, S; Nopoulos, P; O'Leary, D S; Andreasen, N CSeptember 1999Not Determined
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10450260Create StudyChange in basal ganglia volume over 2 years in patients with schizophrenia: typical versus atypical neuroleptics.The American journal of psychiatryCorson PW, Nopoulos P, Miller DD, Arndt S, Andreasen NCAugust 1999Not Determined
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9695445Create StudyPsychiatric disorders in children and adolescents after severe traumatic brain injury: a controlled study.Journal of the American Academy of Child and Adolescent PsychiatryMax JE, Koele SL, Smith WL, Sato Y, Lindgren SD, Robin DA, Arndt SAugust 1998Not Determined
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9046987Create StudyThe effect of antipsychotic medication on relative cerebral blood perfusion in schizophrenia: assessment with technetium-99m hexamethyl-propyleneamine oxime single photon emission computed tomography.Biological psychiatryMiller, D D; Rezai, K; Alliger, R; Andreasen, N CMarch 1, 1997Not Determined
9040920Create StudyThe role of the thalamus in schizophrenia.Canadian journal of psychiatry. Revue canadienne de psychiatrieAndreasen, N CFebruary 1997Not Determined
9024452Create StudyMagnetic resonance imaging of brain anomalies in fetal alcohol syndrome.PediatricsSwayze 2nd, V W; Johnson, V P; Hanson, J W; Piven, J; Sato, Y; Giedd, J N; Mosnik, D; Andreasen, N CFebruary 1997Not Determined
9017111Create StudyThe core symptoms of schizophrenia.Annals of medicineFlaum, M; Schultz, S KDecember 1996Not Determined
9015796Create StudyTardive dyskinesia exacerbated after ingestion of phenylalanine by schizophrenic patients.Neuropsychopharmacology : official publication of the American College of NeuropsychopharmacologyMosnik DM, Spring B, Rogers K, Baruah SFebruary 1997Not Determined
8994458Create StudySelf-reported aggressive behavior in patients with stroke.The Journal of nervous and mental diseaseParadiso, S; Robinson, R G; Arndt, SDecember 1996Not Determined
8919716Create StudyRegional brain enlargement in autism: a magnetic resonance imaging study.Journal of the American Academy of Child and Adolescent PsychiatryPiven J, Arndt S, Bailey J, Andreasen NApril 1996Not Determined
8898701Create StudyTests for comparing images based on randomization and permutation methods.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and MetabolismArndt S, Cizadlo T, Andreasen NC, Heckel D, Gold S, O'Leary DSNovember 1996Not Determined
8876014Create StudyLandmark-based registration and measurement of magnetic resonance images: a reliability study.Psychiatry researchArndt, S; Rajarethinam, R; Cizadlo, T; O'Leary, D; Downhill, J; Andreasen, N CJuly 31, 1996Not Determined
8847654Create StudySymptom dimensions and brain morphology in schizophrenia and related psychotic disorders.Journal of psychiatric researchFlaum, M; O'Leary, D S; Swayze 2nd, V W; Miller, D D; Arndt, S; Andreasen, N CJuly 1995Not Determined
8790444Create StudySchizophrenia and cognitive dysmetria: a positron-emission tomography study of dysfunctional prefrontal-thalamic-cerebellar circuitry.Proceedings of the National Academy of Sciences of the United States of AmericaAndreasen, N C; O'Leary, D S; Cizadlo, T; Arndt, S; Rezai, K; Ponto, L L; Watkins, G L; Hichwa, R DSeptember 3, 1996Not Determined
8784225Create StudySample size and statistical power in [15O]H2O studies of human cognition.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and MetabolismAndreasen NC, Arndt S, Cizadlo T, O'Leary DS, Watkins GL, Ponto LL, Hichwa RDSeptember 1996Not Determined
8664203Create StudyNo difference found between winter- and non-winter-born schizophrenic cases.Schizophrenia researchNovember 1995Not Determined
8633695Create StudyWhen does amphetamine-induced psychosis become schizophrenia?The American journal of psychiatryFlaum M, Schultz SKJune 1996Not Determined
8580223Create StudyWithdrawal-emergent dyskinesia in patients with schizophrenia during antipsychotic discontinuation.Biological psychiatrySchultz SK, Miller DD, Arndt S, Ziebell S, Gupta S, Andreasen NCDecember 1, 1995Not Determined
8576490Create StudyAutomatic atlas-based volume estimation of human brain regions from MR images.Journal of computer assisted tomographyAndreasen, N C; Rajarethinam, R; Cizadlo, T; Arndt, S; Swayze 2nd, V W; Flashman, L A; O'Leary, D S; Ehrhardt, J C; Yuh, W TJanuary 1996Not Determined
8565446Create StudyThe reliability of distinguishing primary versus secondary negative symptoms.Comprehensive psychiatryFlaum, M; Andreasen, NNovember 1995Not Determined
8526236Create StudyBrain morphology in first-episode schizophrenia.The American journal of psychiatryNopoulos P, Torres I, Flaum M, Andreasen NC, Ehrhardt JC, Yuh WTDecember 1995Not Determined
7637483Create StudySymptoms, signs, and diagnosis of schizophrenia.Lancet (London, England)Andreasen, N CAugust 19, 1995Not Determined
7625461Create StudyAn MRI study of brain size in autism.The American journal of psychiatryPiven J, Arndt S, Bailey J, Havercamp S, Andreasen NC, Palmer PAugust 1995Not Determined
7485619Create StudyRemembering the past: two facets of episodic memory explored with positron emission tomography.The American journal of psychiatryAndreasen, N C; O'Leary, D S; Cizadlo, T; Arndt, S; Rezai, K; Watkins, G L; Ponto, L L; Hichwa, R DNovember 1995Not Determined
helpcenter.collection.publications-tab

NDA Help Center

Collection - Publications

The number of Publications is displayed in parentheses next to the tab name. Clicking on any of the Publication Titles will open the Publication in a new internet browsing tab.

Collection Owners, Program Officers, and users with Submission or Administrative Privileges for the Collection may mark a publication as either Relevant or Not Relevant in the Status column.

Frequently Asked Questions

  • How can I determine if a publication is relevant?
    Publications are considered relevant to a collection when the data shared is directly related to the project or collection.
  • Where does the NDA get the publications?
    PubMed, an online library containing journals, articles, and medical research. Sponsored by NiH and National Library of Medicine (NLM).

Glossary

  • Create Study
    A link to the Create an NDA Study page that can be clicked to start creating an NDA Study with information such as the title, journal and authors automatically populated.
  • Not Determined Publication
    Indicates that the publication has not yet been reviewed and/or marked as Relevant or Not Relevant so it has not been determined whether an NDA Study is expected.
  • Not Relevant Publication
    A publication that is not based on data related to the aims of the grant/project associated with the Collection or not based on any data such as a review article and, therefore, an NDA Study is not expected to be created.
  • PubMed
    PubMed provides citation information for biomedical and life sciences publications and is managed by the U.S. National Institutes of Health's National Library of Medicine.
  • PubMed ID
    The PUBMed ID is the unique ID number for the publication as recorded in the PubMed database.
  • Relevant Publication
    A publication that is based on data related to the aims of the grant/project associated with the Collection and, therefore, an NDA Study is expected to be created.
Data Expected List: Mandatory Data Structures

These data structures are mandatory for your NDA Collection. Please update the Targeted Enrollment number to accurately represent the number of subjects you expect to submit for the entire study.

For NIMH HIV-related research that involves human research participants: Select the dictionary or dictionaries most appropriate for your research. If your research does not require all three data dictionaries, just ignore the ones you do not need. There is no need to delete extra data dictionaries from your NDA Collection. You can adjust the Targeted Enrollment column in the Data Expected tab to “0” for those unnecessary data dictionaries. At least one of the three data dictionaries must have a non-zero value.

Data ExpectedTargeted EnrollmentInitial SubmissionSubjects SharedStatus
Research Subject and Pedigree info icon
10007/15/2015
275
Approved
To create your project's Data Expected list, use the "+New Data Expected" to add or request existing structures and to request new Data Structures that are not in the NDA Data Dictionary.

If the Structure you need already exists, locate it and specify your dates and enrollment when adding it to your Data Expected list. If you require changes to the Structure you need, select the indicator stating "No, it requires changes to meet research needs," and upload a file containing your requested changes.

If the structure you need is not yet defined in the Data Dictionary, you can select "Upload Definition" and attach the necessary materials to request its creation.

When selecting the expected dates for your data, make sure to follow the standard Data Sharing Regimen and choose dates within the date ranges that correspond to your project start and end dates.

Please visit the Completing Your Data Expected Tutorial for more information.
Data Expected List: Data Structures per Research Aims

These data structures are specific to your research aims and should list all data structures in which data will be collected and submitted for this NDA Collection. Please update the Targeted Enrollment number to accurately represent the number of subjects you expect to submit for the entire study.

Data ExpectedTargeted EnrollmentInitial SubmissionSubjects SharedStatus
Scales for the Assessment of Positive/Negative Symptoms info icon
10001/15/2015
60
Approved
Wechsler Adult Intelligence Scale info icon
10001/15/2015
163
Approved
Comprehensive Assessment of Symptoms and History info icon
10001/15/2015
150
Approved
Imaging (Structural, fMRI, DTI, PET, microscopy) info icon
10001/15/2015
267
Approved
PSYCH Instrument info icon
10001/15/2015
150
Approved
Structure not yet defined
No Status history for this Data Expected has been recorded yet
helpcenter.collection.data-expected-tab

NDA Help Center

Collection - Data Expected

The Data Expected tab displays the list of all data that NDA expects to receive in association with the Collection as defined by the contributing researcher, as well as the dates for the expected initial upload of the data, and when it is first expected to be shared, or with the research community. Above the primary table of Data Expected, any publications determined to be relevant to the data within the Collection are also displayed - members of the contributing research group can use these to define NDA Studies, connecting those papers to underlying data in NDA.

The tab is used both as a reference for those accessing shared data, providing information on what is expected and when it will be shared, and as the primary tracking mechanism for contributing projects. It is used by both contributing primary researchers, secondary researchers, and NIH Program and Grants Management staff.

Researchers who are starting their project need to update their Data Expected list to include all the Data Structures they are collecting under their grant and set their initial submission and sharing schedule according to the NDA Data Sharing Regimen.

To add existing Data Structures from the Data Dictionary, to request new Data Structure that are not in the Dictionary, or to request changes to existing Data Structures, click "+New Data Expected".

For step-by-step instructions on how to add existing Data Structures, request changes to an existing Structure, or request a new Data Structure, please visit the Completing Your Data Expected Tutorial.

If you are a contributing researcher creating this list for the first time, or making changes to the list as your project progress, please note the following:

  • Although items you add to the list and changes you make are displayed, they are not committed to the system until you Save the entire page using the "Save" button at the bottom of your screen. Please Save after every change to ensure none of your work is lost.
  • If you attempt to add a new structure, the title you provide must be unique - if another structure exists with the same name your change will fail.
  • Adding a new structure to this list is the only way to request the creation of a new Data Dictionary definition.

Frequently Asked Questions

  • What is an NDA Data Structure?
    An NDA Data Structure is comprised of multiple Data Elements to make up an electronic definition of an assessment, measure, questionnaire, etc will have a corresponding Data Structure.
  • What is the NDA Data Dictionary?
    The NDA Data Dictionary is comprised of electronic definitions known as Data Structures.

Glossary

  • Analyzed Data
    Data specific to the primary aims of the research being conducted (e.g. outcome measures, other dependent variables, observations, laboratory results, analyzed images, volumetric data, etc.) including processed images.
  • Data Item
    Items listed on the Data Expected list in the Collection which may be an individual and discrete Data Structure, Data Structure Category, or Data Structure Group.
  • Data Structure
    A defined organization and group of Data Elements to represent an electronic definition of a measure, assessment, questionnaire, or collection of data points. Data structures that have been defined in the NDA Data Dictionary are available at https://nda.nih.gov/general-query.html?q=query=data-structure
  • Data Structure Category
    An NDA term describing the affiliation of a Data Structure to a Category, which may be disease/disorder or diagnosis related (Depression, ADHD, Psychosis), specific to data type (MRI, eye tracking, omics), or type of data (physical exam, IQ).
  • Data Structure Group
    A Data Item listed on the Data Expected tab of a Collection that indicates a group of Data Structures (e.g., ADOS or SCID) for which data may be submitted instead of a specific Data Structure identified by version, module, edition, etc. For example, the ADOS Data Structure Category includes every ADOS Data Structure such as ADOS Module 1, ADOS Module 2, ADOS Module 1 - 2nd Edition, etc. The SCID Data Structure Group includes every SCID Data Structure such as SCID Mania, SCID V Mania, SCID PTSD, SCID-V Diagnosis, and more.
  • Evaluated Data
    A new Data Structure category, Evaluated Data is analyzed data resulting from the use of computational pipelines in the Cloud and can be uploaded directly back to a miNDAR database. Evaluated Data is expected to be listed as a Data Item in the Collection's Data Expected Tab.
  • Imaging Data
    Imaging+ is an NDA term which encompasses all imaging related data including, but not limited to, images (DTI, MRI, PET, Structural, Spectroscopy, etc.) as well as neurosignal data (EEG, fMRI, MEG, EGG, eye tracking, etc.) and Evaluated Data.
  • Initial Share Date
    Initial Submission and Initial Share dates should be populated according to the NDA Data Sharing Terms and Conditions. Any modifications to these will go through the approval processes outlined above. Data will be shared with authorized users upon publication (via an NDA Study) or 1-2 years after the grant end date specified on the first Notice of Award, as defined in the applicable Data Sharing Terms and Conditions.
  • Initial Submission Date
    Initial Submission and Initial Share dates should be populated according to these NDA Data Sharing Terms and Conditions. Any modifications to these will go through the approval processes outlined above. Data for all subjects is not expected on the Initial Submission Date and modifications may be made as necessary based on the project's conduct.
  • Research Subject and Pedigree
    An NDA created Data Structure used to convey basic information about the subject such as demographics, pedigree (links family GUIDs), diagnosis/phenotype, and sample location that are critical to allow for easier querying of shared data.
  • Submission Cycle
    The NDA has two Submission Cycles per year - January 15 and July 15.
  • Submission Exemption
    An interface to notify NDA that data may not be submitted during the upcoming/current submission cycle.

Collection Owners and those with Collection Administrator permission, may edit a collection. The following is currently available for Edit on this page:

Associated Studies

Studies that have been defined using data from a Collection are important criteria to determine the value of data shared. The number of subjects column displays the counts from this Collection that are included in a Study, out of the total number of subjects in that study. The Data Use column represents whether or not the study is a primary analysis of the data or a secondary analysis. State indicates whether the study is private or shared with the research community.

Study NameDOIAbstractCollection/Study SubjectsData UsageState
No records found.
helpcenter.collection.associated-studies-tab

NDA Help Center

Collection - Associated Studies

Clicking on the Study Title will open the study details in a new internet browser tab. The Abstract is available for viewing, providing the background explanation of the study, as provided by the Collection Owner.

Primary v. Secondary Analysis: The Data Usage column will have one of these two choices. An associated study that is listed as being used for Primary Analysis indicates at least some and potentially all of the data used was originally collected by the creator of the NDA Study. Secondary Analysis indicates the Study owner was not involved in the collection of data, and may be used as supporting data.

Private v. Shared State: Studies that remain private indicate the associated study is only available to users who are able to access the collection. A shared study is accessible to the general public.

Frequently Asked Questions

  • How do I associate a study to my collection?
    Studies are associated to the Collection automatically when the data is defined in the Study.

Glossary

  • Associated Studies Tab
    A tab in a Collection that lists the NDA Studies that have been created using data from that Collection including both Primary and Secondary Analysis NDA Studies.
Edit