NIMH Data Archive - Data

Genomics

Neuroimaging

Phenotype¹

New Trial
Clinical Trial

¹ Numbers reported are subjects by age

New Project
Grant/Project Number

Format should be in the following format: Activity Code, Institute Abbreviation, and Serial Number. Grant Type, Support Year, and Suffix should be excluded. For example, grant 1R01MH123456-01A1 should be entered R01MH123456

Collection - Use Existing Experiment

To associate an experiment to the current collection, just select an axperiment from the table below then click the associate experiment button to persist your changes (saving the collection is not required). Note that once an experiment has been associated to two or more collections, the experiment will not longer be editable.

The table search feature is case insensitive and targets the experiment id, experiment name and experiment type columns. The experiment id is searched only when the search term entered is a number, and filtered using a startsWith comparison. When the search term is not numeric the experiment name is used to filter the results.

Select	Experiment Id	Experiment Name	Experiment Type	Created On

24	HI-NGS_R1	Omics	02/16/2011
475	MB1-10 (CHOP)	Omics	06/07/2016
490	Illumina Infinium PsychArray BeadChip Assay	Omics	07/07/2016
501	PharmacoBOLD Resting State	fMRI	07/27/2016
506	PVPREF	Omics	08/05/2016
509	ABC-CT Resting v2	EEG	08/18/2016
13	Comparison of FI expression in Autistic and Neurotypical Homo Sapiens	Omics	12/28/2010
18	AGRE/Broad Affymetrix 5.0 Genotype Experiment	Omics	01/06/2011
22	Stitching PCR Sequencing	Omics	02/14/2011
26	ASD_Methylation	Omics	03/01/2011
29	Microarray family 03 (father, mother, sibling)	Omics	03/24/2011
37	Standard paired-end sequencing of BCRs	Omics	04/19/2011
38	Illumina Mate-Pair BCR sequencing	Omics	04/19/2011
39	Custom Jumping Libraries	Omics	04/19/2011
40	Custom CapBP	Omics	04/19/2011
41	Immunofluorescence	Omics	05/11/2011
43	Autism brain sample genotyping, Illumina	Omics	05/16/2011
47	ARRA Autism Sequencing Collaboration at Baylor. SOLiD 4 System	Omics	08/01/2011
53	AGRE Omni1-quad	Omics	10/11/2011
59	AGP genotyping	Omics	04/03/2012
60	Ultradeep 454 sequencing of synaptic genes from postmortem cerebella of individuals with ASD and neurotypical controls	Omics	06/23/2012
63	Microemulsion PCR and Targeted Resequencing for Variant Detection in ASD	Omics	07/20/2012
76	Whole Genome Sequencing in Autism Families	Omics	01/03/2013
519	Resting	fMRI	11/08/2016
90	Genotyped IAN Samples	Omics	07/09/2013
91	NJLAGS Axiom Genotyping Array	Omics	07/16/2013
93	AGP genotyping (CNV)	Omics	09/06/2013
106	Longitudinal Sleep Study. H20 200. Channel set 2	EEG	11/07/2013
107	Longitudinal Sleep Study. H20 200. Channel set 3	EEG	11/07/2013
108	Longitudinal Sleep Study. AURA 200	EEG	11/07/2013
105	Longitudinal Sleep Study. H20 200. Channel set 1	EEG	11/07/2013
109	Longitudinal Sleep Study. AURA 400	EEG	11/07/2013
116	Gene Expression Analysis WG-6	Omics	01/07/2014
131	Jeste Lab UCLA ACEii: Charlie Brown and Sesame Street - Project 1	Eye Tracking	02/27/2014
132	Jeste Lab UCLA ACEii: Animacy - Project 1	Eye Tracking	02/27/2014
133	Jeste Lab UCLA ACEii: Mom Stranger - Project 2	Eye Tracking	02/27/2014
134	Jeste Lab UCLA ACEii: Face Emotion - Project 3	Eye Tracking	02/27/2014
145	AGRE/FMR1_Illumina.JHU	Omics	04/14/2014
146	AGRE/MECP2_Sanger.JHU	Omics	04/14/2014
147	AGRE/MECP2_Junior.JHU	Omics	04/14/2014
151	Candidate Gene Identification in familial Autism	Omics	06/09/2014
152	NJLAGS Whole Genome Sequencing	Omics	07/01/2014
154	Math Autism Study - Vinod Menon	fMRI	07/15/2014
155	Resting	fMRI	07/25/2014
156	Speech	fMRI	07/25/2014
159	Emotion	fMRI	07/25/2014
160	syllable contrast	EEG	07/29/2014
167	School-age naturalistic stimuli	Eye Tracking	09/19/2014
44	AGRE/Broad Affymetrix 5.0 Genotype Experiment	Omics	06/27/2011
45	Exome Sequencing of 20 Sporadic Cases of Autism Spectrum Disorder	Omics	07/15/2011

Collection - Add Experiment

Add Supporting Documentation

Funding Source:
URL:

To add an existing Data Structure, enter its title in the search bar. If you need to request changes, select the indicator "No, it requires changes to meet research needs" after selecting the Structure, and upload the file with the request changes specific to the selected Data Structure. Your file should follow the Request Changes Procedure. If the Data Structure does not exist, select "Request New Data Structure" and upload the appropriate zip file.

Use/Modify Existing Data Structure

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Data Structures:

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The Data Expected list for this Collection shows some raw data as missing. Contact the NDA Help Desk with any questions.

Please confirm that you will not be enrolling any more subjects and that all raw data has been collected and submitted.

Collection Updated

Your Collection is now in Data Analysis phase and exempt from biannual submissions. Analyzed data is still expected prior to publication or no later than the project end date.

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[CMS]

Unable to change collection phase where targeted enrollment is less than 90%

You have requested to move the sharing dates for the following assessments:

Data Expected Item	Original Sharing Date	New Sharing Date

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Towards Multisystem-Brain Successful Aging in Schizophrenia Spectrum #2994

General
Experiments (1)
Shared Data
Publications (58)
Data Expected (12)
Associated Studies (0)

Collection Title	Collection Investigators	Collection Description
Collection Title:	Towards Multisystem-Brain Successful Aging in Schizophrenia Spectrum
Collection Investigators:	Elliot Hong
Collection Description:	Brain imaging research has revealed accelerated age-related white matter, neurochemical and perhaps cortical changes in patients with schizophrenia spectrum disorders. However, imaging studies are typically brain-focused without system-level investigations on the risk factors. Patients with schizophrenia spectrum disorders also have a much shorter lifespan and high morbidity and mortality. However, medical comorbidity studies typically do not include brain-based investigations. It remains unclear why schizophrenia spectrum disorders have high age-related medical burden. Cumulative stress effects are predictive of successful aging in healthy older adults. In patients with schizophrenia spectrum disorders, cumulative stress may disrupt brain structure and function, and or impaired brain structure and function may distort normal responses to stress leading to increased cumulative stress effects. The proposal research will study cumulative stress and brain imaging age-progression in an age span of 45 years, using a combined longitudinal and age-cohort cross-sectional design. The study proposes to track the progression of stress-related risk factors in the periphery, and the age-related changes in the brain, and to determine whether they will independently or interactively contribute to age-related medical health and functional outcomes in patients with schizophrenia spectrum disorders. These findings may guide the development of clinically actionable strategies to intercept abnormal aging and promote successful aging in patients with this devastating illness.
Data Repository:	NIMH Data Archive
Permission Group:
Collection Creation Date:	08/17/2018
Collection Phase:	Enrolling
Blinded Clinical Trial:	No
Total Funded Amount:	$3,672,987.00
Subjects Shared:	211

{"values":[]}

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Funding Sources:

Funding Source Name	Funding Source URL
NIH - Extramural	None

Supporting Documentation:

Grant Information:

Project Number	Project Title	Start Date	End Date	Planned Enrollment	Actual Enrollment	Organization	Funds Obligated
R01MH116948-01	Towards Multisystem-Brain Successful Aging in Schizophrenia Spectrum	08/01/2018	04/30/2025	420	501	UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON	$3,672,987.00

Clinical Trials:

helpcenter.collection.general-tab

Collection - General Tab

Fields available for edit on the top portion of the page include:

Collection Title
Investigators
Collection Description
Collection Phase
Funding Source
Clinical Trials

Collection Phase: The current status of a research project submitting data to an NDA Collection, based on the timing of the award and/or the data that have been submitted.

Pre-Enrollment: The default entry made when the NDA Collection is created.
Enrolling: Data have been submitted to the NDA Collection or the NDA Data Expected initial submission date has been reached for at least one data structure category in the NDA Collection.
Data Analysis: Subject level data collection for the research project is completed and has been submitted to the NDA Collection. The NDA Collection owner or the NDA Help Desk may set this phase when they’ve confirmed data submission is complete and submitted subject counts match at least 90% of the target enrollment numbers in the NDA Data Expected. Data submission reminders will be turned off for the NDA Collection.
Funding Completed: The NIH grant award (or awards) associated with the NDA Collection has reached its end date. NDA Collections in Funding Completed phase are assigned a subphase to indicate the status of data submission.
- The Data Expected Subphase indicates that NDA expects more data will be submitted
- The Closeout Subphase indicates the data submission is complete.
- The Sharing Not Met Subphase indicates that data submission was not completed as expected.

Blinded Clinical Trial Status:

This status is set by a Collection Owner and indicates the research project is a double blinded clinical trial. When selected, the public view of Data Expected will show the Data Expected items and the Submission Dates, but the targeted enrollment and subjects submitted counts will not be displayed.
Targeted enrollment and subjects submitted counts are visible only to NDA Administrators and to the NDA Collection or as the NDA Collection Owner.
When an NDA Collection that is flagged Blinded Clinical Trial reaches the maximum data sharing date for that Data Repository (see https://nda.nih.gov/nda/sharing-regimen.html), the embargo on Data Expected information is released.

Funding Source

The organization(s) responsible for providing the funding is listed here.

Supporting Documentation

Users with Submission privileges, as well as Collection Owners, Program Officers, and those with Administrator privileges, may upload and attach supporting documentation. By default, supporting documentation is shared to the general public, however, the option is also available to limit this information to qualified researchers only.

Grant Information

Identifiable details are displayed about the Project of which the Collection was derived from. You may click in the Project Number to view a full report of the Project captured by the NIH.

Clinical Trials

Any data that is collected to support or further the research of clinical studies will be available here. Collection Owners and those with Administrator privileges may add new clinical trials.

Frequently Asked Questions

How does the NIMH Data Archive (NDA) determine which Permission Group data are submitted into?

During Collection creation, NDA staff determine the appropriate Permission Group based on the type of data to be submitted, the type of access that will be available to data access users, and the information provided by the Program Officer during grant award.
How do I know when a NDA Collection has been created?

When a Collection is created by NDA staff, an email notification will automatically be sent to the PI(s) of the grant(s) associated with the Collection to notify them.
Is a single grant number ever associated with more than one Collection?

The NDA system does not allow for a single grant to be associated with more than one Collection; therefore, a single grant will not be listed in the Grant Information section of a Collection for more than one Collection.
Why is there sometimes more than one grant included in a Collection?

In general, each Collection is associated with only one grant; however, multiple grants may be associated if the grant has multiple competing segments for the same grant number or if multiple different grants are all working on the same project and it makes sense to hold the data in one Collection (e.g., Cooperative Agreements).

Glossary

Administrator Privilege

A privilege provided to a user associated with an NDA Collection or NDA Study whereby that user can perform a full range of actions including providing privileges to other users.
Collection Owner

Generally, the Collection Owner is the contact PI listed on a grant. Only one NDA user is listed as the Collection owner. Most automated emails are primarily sent to the Collection Owner.
Collection Phase
The Collection Phase provides information on data submission as opposed to grant/project completion so while the Collection phase and grant/project phase may be closely related they are often different. Collection users with Administrative Privileges are encouraged to edit the Collection Phase. The Program Officer as listed in eRA (for NIH funded grants) may also edit this field. Changes must be saved by clicking the Save button at the bottom of the page. This field is sortable alphabetically in ascending or descending order. Collection Phase options include:
- Pre-Enrollment: A grant/project has started, but has not yet enrolled subjects.
- Enrolling: A grant/project has begun enrolling subjects. Data submission is likely ongoing at this point.
- Data Analysis: A grant/project has completed enrolling subjects and has completed all data submissions.
- Funding Completed: A grant/project has reached the project end date.
Collection Title

An editable field with the title of the Collection, which is often the title of the grant associated with the Collection.
Grant

Provides the grant number(s) for the grant(s) associated with the Collection. The field is a hyperlink so clicking on the Grant number will direct the user to the grant information in the NIH Research Portfolio Online Reporting Tools (RePORT) page.
Supporting Documentation

Various documents and materials to enable efficient use of the data by investigators unfamiliar with the project and may include the research protocol, questionnaires, and study manuals.
NIH Research Initiative

NDA Collections may be organized by scientific similarity into NIH Research Initiatives, to facilitate query tool user experience. NIH Research Initiatives map to one or multiple Funding Opportunity Announcements.
Permission Group

Access to shared record-level data in NDA is provisioned at the level of a Permission Group. NDA Permission Groups consist of one or multiple NDA Collections that contain data with the same subject consents.
Planned Enrollment

Number of human subject participants to be enrolled in an NIH-funded clinical research study. The data is provided in competing applications and annual progress reports.
Actual Enrollment

Number of human subjects enrolled in an NIH-funded clinical research study. The data is provided in annual progress reports.
NDA Collection

A virtual container and organization structure for data and associated documentation from one grant or one large project/consortium. It contains tools for tracking data submission and allows investigators to define a wide array of other elements that provide context for the data, including all general information regarding the data and source project, experimental parameters used to collect any event-based data contained in the Collection, methods, and other supporting documentation. They also allow investigators to link underlying data to an NDA Study, defining populations and subpopulations specific to research aims.
Data Use Limitations

Data Use Limitations (DULs) describe the appropriate secondary use of a dataset and are based on the original informed consent of a research participant. NDA only accepts consent-based data use limitations defined by the NIH Office of Science Policy.
Total Subjects Shared

The total number of unique subjects for whom data have been shared and are available for users with permission to access data.

Contact NDA Help Desk

ID	Name	Created Date	Status	Type
1318	Resting state	07/12/2019	Approved	fMRI

helpcenter.collection.experiments-tab

Collection - Experiments

The number of Experiments included is displayed in parentheses next to the tab name. You may download all experiments associated with the Collection via the Download button. You may view individual experiments by clicking the Experiment Name and add them to the Filter Cart via the Add to Cart button.

Collection Owners, Program Officers, and users with Submission or Administrative Privileges for the Collection may create or edit an Experiment.

Please note: The creation of an NDA Experiment does not necessarily mean that data collected, according to the defined Experiment, has been submitted or shared.

Frequently Asked Questions

Can an Experiment be associated with more than one Collection?
Yes -see the “Copy” button in the bottom left when viewing an experiment. There are two actions that can be performed via this button:
1. Copy the experiment with intent for modifications.
2. Associate the experiment to the collection. No modifications can be made to the experiment.

Glossary

Experiment Status

An Experiment must be Approved before data using the associated Experiment_ID may be uploaded.
Experiment ID

The ID number automatically generated by NDA which must be included in the appropriate file when uploading data to link the Experiment Definition to the subject record.

Contact NDA Help Desk

Shared Data:

Title	Type	Number of Subjects
Beck Depression Inventory	Clinical Assessments	211
Blood Pressure Form	Clinical Assessments	211
Brief Negative Symptom Scale	Clinical Assessments	211
Brief Psychiatric Rating Scale	Clinical Assessments	211
Childhood Trauma Questionnaire	Clinical Assessments	211
Digit Symbol Substitution Test	Clinical Assessments	211
Edinburgh Handedness Inventory	Clinical Assessments	211
Fagerstrom Test for Nicotine Dependence	Clinical Assessments	211
Height and Weight	Clinical Assessments	211
Image	Imaging	181
Perceived Stress Scale	Clinical Assessments	211
Pittsburgh Sleep Quality Index	Clinical Assessments	211
Research Subject	Clinical Assessments	211

helpcenter.collection.shared-data-tab

Collection - Shared Data

This tab provides a quick overview of the Data Structure title, Data Type, and Number of Subjects that are currently Shared for the Collection. The information presented in this tab is automatically generated by NDA and cannot be edited. If no information is visible on this tab, this would indicate the Collection does not have shared data or the data is private.

The shared data is available to other researchers who have permission to access data in the Collection's designated Permission Group(s). Use the Download button to get all shared data from the Collection to the Filter Cart.

Frequently Asked Questions

How will I know if another researcher uses data that I shared through the NIMH Data Archive (NDA)?

To see what data your project have submitted are being used by a study, simply go the Associated Studies tab of your collection. Alternatively, you may review an NDA Study Attribution Report available on the General tab.
Can I get a supplement to share data from a completed research project?

Often it becomes more difficult to organize and format data electronically after the project has been completed and the information needed to create a GUID may not be available; however, you may still contact a program staff member at the appropriate funding institution for more information.
Can I get a supplement to share data from a research project that is still ongoing?

Unlike completed projects where researchers may not have the information needed to create a GUID and/or where the effort needed to organize and format data becomes prohibitive, ongoing projects have more of an opportunity to overcome these challenges. Please contact a program staff member at the appropriate funding institution for more information.

Glossary

Data Structure

A defined organization and group of Data Elements to represent an electronic definition of a measure, assessment, questionnaire, or collection of data points. Data structures that have been defined in the NDA Data Dictionary are available at https://nda.nih.gov/general-query.html?q=query=data-structure
Data Type

A grouping of data by similar characteristics such as Clinical Assessments, Omics, or Neurosignal data.
Shared

The term 'Shared' generally means available to others; however, there are some slightly different meanings based on what is Shared. A Shared NDA Study is viewable and searchable publicly regardless of the user's role or whether the user has an NDA account. A Shared NDA Study does not necessarily mean that data used in the NDA Study have been shared as this is independently determined. Data are shared according the schedule defined in a Collection's Data Expected Tab and/or in accordance with data sharing expectations in the NDA Data Sharing Terms and Conditions. Additionally, Supporting Documentation uploaded to a Collection may be shared independent of whether data are shared.

Contact NDA Help Desk

Collection Owners and those with Collection Administrator permission, may edit a collection. The following is currently available for Edit on this page:

Publications

Publications relevant to NDA data are listed below. Most displayed publications have been associated with the grant within Pubmed. Use the "+ New Publication" button to add new publications. Publications relevant/not relevant to data expected are categorized. Relevant publications are then linked to the underlying data by selecting the Create Study link. Study provides the ability to define cohorts, assign subjects, define outcome measures and lists the study type, data analysis and results. Analyzed data and results are expected in this way.

PubMed ID	Study	Title	Journal	Authors	Date	Status
39495221	Create Study	Age-related decline in blood-brain barrier function is more pronounced in males than females in parietal and temporal regions.	eLife	Shao, Xingfeng; Shou, Qinyang; Felix, Kimberly; Ojogho, Brandon; Jiang, Xuejuan; Gold, Brian T; Herting, Megan M; Goldwaser, Eric L; Kochunov, Peter; Hong, Elliot; Pappas, Ioannis; Braskie, Meredith; Kim, Hosung; Cen, Steven; Jann, Kay; Wang, Danny J J	November 4, 2024	Not Determined
38733800	Create Study	Impact of lifetime stressor exposure on neuroenergetics in schizophrenia spectrum disorders.	Schizophrenia research	Chiappelli, Joshua; Savransky, Anya; Ma, Yizhou; Gao, Si; Kvarta, Mark D; Kochunov, Peter; Slavich, George M; Hong, L Elliot	July 1, 2024	Not Determined
38453003	Create Study	Combining neuroimaging and brain stimulation to test alternative causal pathways for nicotine addiction in schizophrenia.	Brain stimulation	Du, Xiaoming; Choa, Fow-Sen; Chiappelli, Joshua; Bruce, Heather; Kvarta, Mark; Summerfelt, Ann; Ma, Yizhou; Regenold, William T; Walton, Kevin; Wittenberg, George F; Hare, Stephanie; Gao, Si; van der Vaart, Andrew; Zhao, Zhiwei; Chen, Shuo; Kochunov, Peter; Hong, L Elliot	January 1, 2024	Not Determined
38246028	Create Study	Revisiting delusion subtypes in schizophrenia based on their underlying structures.	Journal of psychiatric research	van der Vaart, Andrew D; Ma, Yizhou; Chiappelli, Joshua; Bruce, Heather; Kvarta, Mark D; Warner, Alia; Du, Xiaoming; Adhikari, Bhim M; Sampath, Hemalatha; Kochunov, Peter; Hong, L Elliot	March 1, 2024	Not Determined
38065979	Create Study	Effects of independent versus dependent stressful life events on major symptom domains of schizophrenia.	Schizophrenia (Heidelberg, Germany)	Ma, Yizhou; Chiappelli, Joshua; Kvarta, Mark D; Bruce, Heather; van der Vaart, Andrew; Goldwaser, Eric L; Du, Xiaoming; Sampath, Hemalatha; Lightner, Samantha; Endres, Jane; Yusuf, Akram; Yuen, Alexa; Narvaez, Samantha; Campos-Saravia, Danny; Kochunov, Peter; Hong, L Elliot	December 8, 2023	Not Determined
37750294	Create Study	Reciprocal relationships between stress and depressive symptoms: the essential role of the nucleus accumbens.	Psychological medicine	Ma, Yizhou; Kochunov, Peter; Kvarta, Mark D; LeGates, Tara; Adhikari, Bhim M; Chiappelli, Joshua; van der Vaart, Andrew; Goldwaser, Eric L; Bruce, Heather; Hatch, Kathryn S; Gao, Si; Chen, Shuo; Summerfelt, Ann; Nichols, Thomas E; Hong, L Elliot	April 1, 2024	Not Determined
37078962	Create Study	Evidence of Neurovascular Water Exchange and Endothelial Vascular Dysfunction in Schizophrenia: An Exploratory Study.	Schizophrenia bulletin	Goldwaser, Eric L; Wang, Danny J J; Adhikari, Bhim M; Chiappelli, Joshua; Shao, Xingfeng; Yu, Jiaao; Lu, Tong; Chen, Shuo; Marshall, Wyatt; Yuen, Alexa; Kvarta, Mark; Ma, Yizhou; Du, Xiaoming; Gao, Si; Saeedi, Osamah; Bruce, Heather; Donnelly, Patrick; O'Neill, Hugh; Shuldiner, Alan R; Mitchell, Braxton D; Kochunov, Peter; Hong, L Elliot	September 7, 2023	Not Determined
36948435	Create Study	Ancestral, Pregnancy, and Negative Early-Life Risks Shape Children''s Brain (Dis)similarity to Schizophrenia.	Biological psychiatry	Kochunov, Peter; Ma, Yizhou; Hatch, Kathryn S; Gao, Si; Acheson, Ashley; Jahanshad, Neda; Thompson, Paul M; Adhikari, Bhim M; Bruce, Heather; Van der Vaart, Andrew; Chiappelli, Joshua; Du, Xiaoming; Sotiras, Aris; Kvarta, Mark D; Ma, Tianzhou; Chen, Shuo; Hong, L Elliot	August 15, 2023	Not Determined
36799565	Create Study	Brain deficit patterns of metabolic illnesses overlap with those for major depressive disorder: A new metric of brain metabolic disease.	Human brain mapping	Hatch, Kathryn S; Gao, Si; Ma, Yizhou; Russo, Alessandro; Jahanshad, Neda; Thompson, Paul M; Adhikari, Bhim M; Bruce, Heather; Van der Vaart, Andrew; Sotiras, Aristeidis; Kvarta, Mark D; Nichols, Thomas E; Schmaal, Lianne; Hong, L Elliot; Kochunov, Peter	April 15, 2023	Not Determined
36653335	Create Study	Cortical connectomic mediations on gamma band synchronization in schizophrenia.	Translational psychiatry	Du, Xiaoming; Hare, Stephanie; Summerfelt, Ann; Adhikari, Bhim M; Garcia, Laura; Marshall, Wyatt; Zan, Peng; Kvarta, Mark; Goldwaser, Eric; Bruce, Heather; Gao, Si; Sampath, Hemalatha; Kochunov, Peter; Simon, Jonathan Z; Hong, L Elliot	January 19, 2023	Not Determined
36470375	Create Study	Association between brain similarity to severe mental illnesses and comorbid cerebral, physical, and cognitive impairments.	NeuroImage	Ma, Yizhou; Kvarta, Mark D; Adhikari, Bhim M; Chiappelli, Joshua; Du, Xiaoming; van der Vaart, Andrew; Goldwaser, Eric L; Bruce, Heather; Hatch, Kathryn S; Gao, Si; Summerfelt, Ann; Jahanshad, Neda; Thompson, Paul M; Nichols, Thomas E; Hong, L Elliot; Kochunov, Peter	January 1, 2023	Not Determined
36040723	Create Study	Brain-wide versus genome-wide vulnerability biomarkers for severe mental illnesses.	Human brain mapping	Kochunov, Peter; Ma, Yizhou; Hatch, Kathryn S; Gao, Si; Jahanshad, Neda; Thompson, Paul M; Adhikari, Bhim M; Bruce, Heather; Van der Vaart, Andrew; Goldwaser, Eric L; Sotiras, Aris; Kvarta, Mark D; Ma, Tianzhou; Chen, Shuo; Nichols, Thomas E; Hong, L Elliot	November 1, 2022	Not Determined
35944595	Create Study	Serum hyperhomocysteine and cognitive impairment in first-episode patients with schizophrenia: Moderated by brain cortical thickness.	Neuroscience letters	Lin, Chen; Gou, Mengzhuang; Pan, Shujuan; Tong, Jinghui; Zhou, Yanfang; Xie, Ting; Yu, Ting; Feng, Wei; Li, Yanli; Chen, Song; Tian, Baopeng; Tan, Shuping; Wang, Zhiren; Luo, Xingguang; Li, Chiang-Shan R; Zhang, Ping; Huang, Junchao; Elliot Hong, L; Tan, Yunlong	September 25, 2022	Not Determined
35654451	Create Study	Childhood trauma and cognitive deficits in patients with schizophrenia: mediation by orbitofrontal cortex H-shaped sulci volume.	Journal of psychiatry & neuroscience : JPN	Wang, Leilei; Yin, Yi; Feng, Wei; Zhou, Yanfang; Huang, Junchao; Zhang, Ping; Chen, Song; Fan, Hongzhen; Cui, Yimin; Luo, Xingguang; Tan, Shuping; Wang, Zhiren; Tian, Baopeng; Tian, Li; Li, Chiang-Shan R; Tan, Yunlong	May 1, 2022	Not Determined
35112422	Create Study	The additive impact of cardio-metabolic disorders and psychiatric illnesses on accelerated brain aging.	Human brain mapping	Ryan, Meghann C; Hong, L Elliot; Hatch, Kathryn S; Gao, Si; Chen, Shuo; Haerian, Krystl; Wang, Jingtao; Goldwaser, Eric L; Du, Xiaoming; Adhikari, Bhim M; Bruce, Heather; Hare, Stephanie; Kvarta, Mark D; Jahanshad, Neda; Nichols, Thomas E; Thompson, Paul M; Kochunov, Peter	April 15, 2022	Not Determined
35040662	Create Study	Role of White Matter Microstructure in Impulsive Behavior.	The Journal of neuropsychiatry and clinical neurosciences	Goldwaser, Eric L; Du, Xiaoming; Adhikari, Bhim M; Kvarta, Mark; Chiappelli, Joshua; Hare, Stephanie; Marshall, Wyatt; Savransky, Anya; Carino, Kathleen; Bruce, Heather; Acheson, Ashley; Kochunov, Peter; Hong, L Elliot	January 1, 2022	Not Determined
34890143	Create Study	Separating Clinical and Subclinical Depression by Big Data Informed Structural Vulnerability Index and Its impact on Cognition: ENIGMA Dot Product.	Pacific Symposium on Biocomputing. Pacific Symposium on Biocomputing	Kochunov, Peter; Ma, Yizhou; Hatch, Kathryn S; Schmaal, Lianne; Jahanshad, Neda; Thompson, Paul M; Adhikari, Bhim M; Bruce, Heather; Chiappelli, Joshua; Van der Vaart, Andrew; Goldwaser, Eric L; Sotiras, Aris; Ma, Tianzhou; Chen, Shuo; Nichols, Thomas E; Hong, L Elliot	January 1, 2022	Not Determined
34211106	Create Study	White matter in prolonged glucocorticoid response to psychological stress in schizophrenia.	Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology	Goldwaser, Eric L; Chiappelli, Joshua; Kvarta, Mark D; Du, Xiaoming; Millman, Zachary B; Adhikari, Bhim M; O'Neill, Hugh; Sewell, Jessica; Lightner, Samantha; Vodapalli, Shreya; Ma, Yizhou; Bruce, Heather; Chen, Shuo; Tan, Yunlong; Kochunov, Peter; Elliot Hong, L	December 1, 2021	Not Determined
34010783	Create Study	Aberrant anterior cingulate processing of anticipated threat as a mechanism for psychosis.	Psychiatry research. Neuroimaging	Kvarta, Mark D; Chiappelli, Joshua; West, Jeffrey; Goldwaser, Eric L; Bruce, Heather A; Ma, Yizhou; Kochunov, Peter; Hatch, Kathryn; Gao, Si; Jones, Aaron; O'Neill, Hugh; Du, Xiaoming; Hong, L Elliot	July 30, 2021	Not Determined
33991855	Create Study	Mapping local and long-distance resting connectivity markers of TMS-related inhibition reduction in schizophrenia.	NeuroImage. Clinical	Hare, Stephanie M; Du, Xiaoming; Adhikari, Bhim M; Chen, Shuo; Mo, Chen; Summerfelt, Ann; Kvarta, Mark D; Garcia, Laura; Kochunov, Peter; Elliot Hong, L	January 1, 2021	Not Determined
33730571	Create Study	Transcriptome-wide association study reveals two genes that influence mismatch negativity.	Cell reports	Bhat, Anjali; Irizar, Haritz; Thygesen, Johan Hilge; Kuchenbaecker, Karoline; Pain, Oliver; Adams, Rick A; Zartaloudi, Eirini; Harju-Seppänen, Jasmine; Austin-Zimmerman, Isabelle; Wang, Baihan; Muir, Rebecca; Summerfelt, Ann; Du, Xiaoming Michael; Bruce, Heather; O'Donnell, Patricio; Srivastava, Deepak P; Friston, Karl; Hong, L Elliot; Hall, Mei-Hua; Bramon, Elvira	March 16, 2021	Not Determined
33662656	Create Study	Association of working memory and elevated overnight urinary norepinephrine in patients with schizophrenia.	Journal of psychiatric research	Savransky, Anya; Chiappelli, Joshua; Du, Xiaoming; Carino, Kathleen; Kvarta, Mark; Bruce, Heather; Kochunov, Peter; Goldwaser, Eric; Tan, Yunlong; Hare, Stephanie; Hong, L Elliot	May 1, 2021	Not Determined
33650257	Create Study	Genetic versus stress and mood determinants of sleep in the Amish.	American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics	Bruce, Heather A; Kochunov, Peter; Chiappelli, Joshua; Savransky, Anya; Carino, Kathleen; Sewell, Jessica; Marshall, Wyatt; Kvarta, Mark; McMahon, Francis J; Ament, Seth A; Postolache, Teodor T; O'Connell, Jeff; Shuldiner, Alan; Mitchell, Braxton; Hong, L Elliot	March 1, 2021	Not Determined
33558459	Create Study	The microRNA-195 - BDNF pathway and cognitive deficits in schizophrenia patients with minimal antipsychotic medication exposure.	Translational psychiatry	Pan, Shujuan; Feng, Wei; Li, Yanli; Huang, Junchao; Chen, Song; Cui, Yimin; Tian, Baopeng; Tan, Shuping; Wang, Zhiren; Yao, Shangwu; Chiappelli, Joshua; Kochunov, Peter; Chen, Shuo; Yang, Fude; Li, Chiang-Shan R; Tian, Li; Tan, Yunlong; Elliot Hong, L	February 8, 2021	Not Determined
33530016	Create Study	Comparison of regional brain deficit patterns in common psychiatric and neurological disorders as revealed by big data.	NeuroImage. Clinical	Kochunov, Peter; Ryan, Meghann C; Yang, Qifan; Hatch, Kathryn S; Zhu, Alyssa; Thomopoulos, Sophia I; Jahanshad, Neda; Schmaal, Lianne; Thompson, Paul M; Chen, Shuo; Du, Xiaoming; Adhikari, Bhim M; Bruce, Heather; Hare, Stephanie; Goldwaser, Eric L; Kvarta, Mark D; Nichols, Thomas E; Hong, L Elliot	January 1, 2021	Not Determined
33515249	Create Study	N-methyl-D-aspartate Receptor Antibody and White Matter Deficits in Schizophrenia Treatment-Resistance.	Schizophrenia bulletin	Tong, Jinghui; Zhou, Yanfang; Huang, Junchao; Zhang, Ping; Fan, Fengmei; Chen, Song; Tian, Baopeng; Cui, Yimin; Tian, Li; Tan, Shuping; Wang, Zhiren; Feng, Wei; Yang, Fude; Hare, Stephanie; Goldwaser, Eric L; Bruce, Heather A; Kvarta, Mark; Chen, Shuo; Kochunov, Peter; Tan, Yunlong; Hong, L Elliot	August 21, 2021	Not Determined
33501486	Create Study	Allostatic Load Effects on Cortical and Cognitive Deficits in Essentially Normotensive, Normoweight Patients with Schizophrenia.	Schizophrenia bulletin	Zhou, Yanfang; Huang, Junchao; Zhang, Ping; Tong, Jinghui; Fan, Fengmei; Gou, Mengzhuang; Cui, Yimin; Luo, Xingguang; Tan, Shuping; Wang, Zhiren; Feng, Wei; Yang, Fude; Tian, Baopeng; Tian, Li; Savransky, Anya; Hare, Stephanie; Ryan, Meghann C; Goldwaser, Eric; Chiappelli, Joshua; Chen, Shuo; Kochunov, Peter; Kvarta, Mark; Tan, Yunlong; Hong, L Elliot	July 8, 2021	Not Determined
33493774	Create Study	Local versus long-range connectivity patterns of auditory disturbance in schizophrenia.	Schizophrenia research	Hare, Stephanie M; Adhikari, Bhim M; Du, Xiaoming; Garcia, Laura; Bruce, Heather; Kochunov, Peter; Simon, Jonathan Z; Hong, L Elliot	February 1, 2021	Not Determined
33219208	Create Study	Assessment of brain cholesterol metabolism biomarker 24S-hydroxycholesterol in schizophrenia.	NPJ schizophrenia	Chiappelli, Joshua; Quinton, Maria S; Volfson, Dmitri; Cwik, Michael; Marshall, Wyatt; Bruce, Heather; Goldwaser, Eric; Kvarta, Mark; Summerfelt, Ann; Kochunov, Peter; O'Donnell, Patricio; Hong, Liyi Elliot	November 20, 2020	Not Determined
32463560	Create Study	Translating ENIGMA schizophrenia findings using the regional vulnerability index: Association with cognition, symptoms, and disease trajectory.	Human brain mapping	Kochunov, Peter; Fan, Fengmei; Ryan, Meghann C; Hatch, Kathryn S; Tan, Shuping; Jahanshad, Neda; Thompson, Paul M; van Erp, Theo G M; Turner, Jessica A; Chen, Shuo; Du, Xiaoming; Adhikari, Bhim; Bruce, Heather; Hare, Stephanie; Goldwaser, Eric; Kvarta, Mark; Huang, Junchao; Tong, Jinghui; Cui, Yimin; Cao, Baopeng; Tan, Yunlong; Hong, L Elliot	January 1, 2022	Not Determined
32375159	Create Study	A roadmap for development of neuro-oscillations as translational biomarkers for treatment development in neuropsychopharmacology.	Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology	Javitt, Daniel C; Siegel, Steven J; Spencer, Kevin M; Mathalon, Daniel H; Hong, L Elliot; Martinez, Antigona; Ehlers, Cindy L; Abbas, Atheir I; Teichert, Tobias; Lakatos, Peter; Womelsdorf, Thilo	August 1, 2020	Not Determined
32310840	Create Study	The Role of Hippocampal Functional Connectivity on Multisystem Subclinical Abnormalities in Schizophrenia.	Psychosomatic medicine	Hare, Stephanie M; Chiappelli, Joshua; Savransky, Anya; Adhikari, Bhim M; Wisner, Krista; Kvarta, Mark; Goldwaser, Eric; Du, Xiaoming; Chen, Shuo; Rowland, Laura M; Kochunov, Peter; Hong, L Elliot	July 1, 2020	Not Determined
32301246	Create Study	ENIGMA-DTI: Translating reproducible white matter deficits into personalized vulnerability metrics in cross-diagnostic psychiatric research.	Human brain mapping	Kochunov, Peter; Hong, L Elliot; Dennis, Emily L; Morey, Rajendra A; Tate, David F; Wilde, Elisabeth A; Logue, Mark; Kelly, Sinead; Donohoe, Gary; Favre, Pauline; Houenou, Josselin; Ching, Christopher R K; Holleran, Laurena; Andreassen, Ole A; van Velzen, Laura S; Schmaal, Lianne; Villalón-Reina, Julio E; Bearden, Carrie E; Piras, Fabrizio; Spalletta, Gianfranco; van den Heuvel, Odile A; Veltman, Dick J; Stein, Dan J; Ryan, Meghann C; Tan, Yunlong; van Erp, Theo G M; Turner, Jessica A; Haddad, Liz; Nir, Talia M; Glahn, David C; Thompson, Paul M; Jahanshad, Neda	January 1, 2022	Not Determined
32193296	Create Study	The genetic architecture of the human cerebral cortex.	Science (New York, N.Y.)	Grasby, Katrina L; Jahanshad, Neda; Painter, Jodie N; Colodro-Conde, Lucía; Bralten, Janita; Hibar, Derrek P; Lind, Penelope A; Pizzagalli, Fabrizio; Ching, Christopher R K; McMahon, Mary Agnes B; Shatokhina, Natalia; Zsembik, Leo C P; Thomopoulos, Sophia I; Zhu, Alyssa H; Strike, Lachlan T; Agartz, Ingrid; Alhusaini, Saud; Almeida, Marcio A A; Alnæs, Dag; Amlien, Inge K; Andersson, Micael; Ard, Tyler; Armstrong, Nicola J; Ashley-Koch, Allison; Atkins, Joshua R; Bernard, Manon; Brouwer, Rachel M; Buimer, Elizabeth E L; Bülow, Robin; Bürger, Christian; Cannon, Dara M; Chakravarty, Mallar; Chen, Qiang; Cheung, Joshua W; Couvy-Duchesne, Baptiste; Dale, Anders M; Dalvie, Shareefa; de Araujo, Tânia K; de Zubicaray, Greig I; de Zwarte, Sonja M C; den Braber, Anouk; Doan, Nhat Trung; Dohm, Katharina; Ehrlich, Stefan; Engelbrecht, Hannah-Ruth; Erk, Susanne; Fan, Chun Chieh; Fedko, Iryna O; Foley, Sonya F; Ford, Judith M; Fukunaga, Masaki; Garrett, Melanie E; Ge, Tian; Giddaluru, Sudheer; Goldman, Aaron L; Green, Melissa J; Groenewold, Nynke A; Grotegerd, Dominik; Gurholt, Tiril P; Gutman, Boris A; Hansell, Narelle K; Harris, Mathew A; Harrison, Marc B; Haswell, Courtney C; Hauser, Michael; Herms, Stefan; Heslenfeld, Dirk J; Ho, New Fei; Hoehn, David; Hoffmann, Per; Holleran, Laurena; Hoogman, Martine; Hottenga, Jouke-Jan; Ikeda, Masashi; Janowitz, Deborah; Jansen, Iris E; Jia, Tianye; Jockwitz, Christiane; Kanai, Ryota; Karama, Sherif; Kasperaviciute, Dalia; Kaufmann, Tobias; Kelly, Sinead; Kikuchi, Masataka; Klein, Marieke; Knapp, Michael; Knodt, Annchen R; Krämer, Bernd; Lam, Max; Lancaster, Thomas M; Lee, Phil H; Lett, Tristram A; Lewis, Lindsay B; Lopes-Cendes, Iscia; Luciano, Michelle; Macciardi, Fabio; Marquand, Andre F; Mathias, Samuel R; Melzer, Tracy R; Milaneschi, Yuri; Mirza-Schreiber, Nazanin; Moreira, Jose C V; Mühleisen, Thomas W; Müller-Myhsok, Bertram; Najt, Pablo; Nakahara, Soichiro; Nho, Kwangsik; Olde Loohuis, Loes M; Orfanos, Dimitri Papadopoulos; Pearson, John F; Pitcher, Toni L; Pütz, Benno; Quidé, Yann; Ragothaman, Anjanibhargavi; Rashid, Faisal M; Reay, William R; Redlich, Ronny; Reinbold, Céline S; Repple, Jonathan; Richard, Geneviève; Riedel, Brandalyn C; Risacher, Shannon L; Rocha, Cristiane S; Mota, Nina Roth; Salminen, Lauren; Saremi, Arvin; Saykin, Andrew J; Schlag, Fenja; Schmaal, Lianne; Schofield, Peter R; Secolin, Rodrigo; Shapland, Chin Yang; Shen, Li; Shin, Jean; Shumskaya, Elena; Sønderby, Ida E; Sprooten, Emma; Tansey, Katherine E; Teumer, Alexander; Thalamuthu, Anbupalam; Tordesillas-Gutiérrez, Diana; Turner, Jessica A; Uhlmann, Anne; Vallerga, Costanza Ludovica; van der Meer, Dennis; van Donkelaar, Marjolein M J; van Eijk, Liza; van Erp, Theo G M; van Haren, Neeltje E M; van Rooij, Daan; van Tol, Marie-José; Veldink, Jan H; Verhoef, Ellen; Walton, Esther; Wang, Mingyuan; Wang, Yunpeng; Wardlaw, Joanna M; Wen, Wei; Westlye, Lars T; Whelan, Christopher D; Witt, Stephanie H; Wittfeld, Katharina; Wolf, Christiane; Wolfers, Thomas; Wu, Jing Qin; Yasuda, Clarissa L; Zaremba, Dario; Zhang, Zuo; Zwiers, Marcel P; Artiges, Eric; Assareh, Amelia A; Ayesa-Arriola, Rosa; Belger, Aysenil; Brandt, Christine L; Brown, Gregory G; Cichon, Sven; Curran, Joanne E; Davies, Gareth E; Degenhardt, Franziska; Dennis, Michelle F; Dietsche, Bruno; Djurovic, Srdjan; Doherty, Colin P; Espiritu, Ryan; Garijo, Daniel; Gil, Yolanda; Gowland, Penny A; Green, Robert C; Häusler, Alexander N; Heindel, Walter; Ho, Beng-Choon; Hoffmann, Wolfgang U; Holsboer, Florian; Homuth, Georg; Hosten, Norbert; Jack Jr, Clifford R; Jang, MiHyun; Jansen (see original citation for additional authors)	March 20, 2020	Not Determined
32062167	Create Study	Hippocampus and cognitive domain deficits in treatment-resistant schizophrenia: A comparison with matched treatment-responsive patients and healthy controls✰,✰✰,★,★★.	Psychiatry research. Neuroimaging	Huang, Junchao; Zhu, Yu; Fan, Fengmei; Chen, Song; Hong, Yuan; Cui, Yimin; Luo, Xingguang; Tan, Shuping; Wang, Zhiren; Shang, Lan; Yuan, Ying; Zhang, Jianxin; Yang, Fude; Li, Chiang-Shan R; Rowland, Laura M; Kochunov, Peter; Zhang, Fengyu; Hong, L Elliot; Tan, Yunlong	February 4, 2020	Not Determined
31754041	Create Study	Cardiovascular risks impact human brain N-acetylaspartate in regionally specific patterns.	Proceedings of the National Academy of Sciences of the United States of America	Chiappelli, Joshua; Rowland, Laura M; Wijtenburg, S Andrea; Chen, Hongji; Maudsley, Andrew A; Sheriff, Sulaiman; Chen, Shuo; Savransky, Anya; Marshall, Wyatt; Ryan, Meghann C; Bruce, Heather A; Shuldiner, Alan R; Mitchell, Braxton D; Kochunov, Peter; Hong, L Elliot	December 10, 2019	Not Determined
31603232	Create Study	Choroid Plexus Enlargement and Allostatic Load in Schizophrenia.	Schizophrenia bulletin	Zhou, Yan-Fang; Huang, Jun-Chao; Zhang, Ping; Fan, Feng-Mei; Chen, Song; Fan, Hong-Zhen; Cui, Yi-Min; Luo, Xing-Guang; Tan, Shu-Ping; Wang, Zhi-Ren; Feng, Wei; Yuan, Ying; Yang, Fu-De; Savransky, Anya; Ryan, Meghann; Goldwaser, Eric; Chiappelli, Joshua; Rowland, Laura M; Kochunov, Peter; Tan, Yun-Long; Hong, L Elliot	April 10, 2020	Not Determined
31352812	Create Study	White Matter in Schizophrenia Treatment Resistance.	The American journal of psychiatry	Kochunov, Peter; Huang, Junchao; Chen, Song; Li, Yanli; Tan, Shuping; Fan, Fengmei; Feng, Wei; Wang, Yunhui; Rowland, Laura M; Savransky, Anya; Du, Xiaoming; Chiappelli, Joshua; Chen, Shuo; Jahanshad, Neda; Thompson, Paul M; Ryan, Meghann C; Adhikari, Bhim; Sampath, Hemalatha; Cui, Yimin; Wang, Zhiren; Yang, Fude; Tan, Yunlong; Hong, L Elliot	October 1, 2019	Not Determined
31201848	Create Study	Elevated serum anti-NMDA receptor antibody levels in first-episode patients with schizophrenia.	Brain, behavior, and immunity	Tong, Jinghui; Huang, Junchao; Luo, Xingguang; Chen, Song; Cui, Yimin; An, Huimei; Xiu, Meihong; Tan, Shuping; Wang, Zhiren; Yuan, Ying; Zhang, Jianxin; Yang, Fude; Li, Chiang-Shan R; Hong, L Elliot; Tan, Yunlong	October 1, 2019	Not Determined
31123971	Create Study	Cingulum and abnormal psychological stress response in schizophrenia.	Brain imaging and behavior	Wisner, Krista M; Chiappelli, Joshua; Savransky, Anya; Fisseha, Feven; Rowland, Laura M; Kochunov, Peter; Hong, L Elliot	April 1, 2020	Not Determined
31058523	Create Study	A working memory related mechanism of auditory hallucinations.	Journal of abnormal psychology	Gaudiot, Christopher; Du, Xiaoming; Summerfelt, Ann; Hare, Stephanie M; Bustillo, Juan R; Rowland, Laura M; Hong, L Elliot	July 1, 2019	Not Determined
30969327	Create Study	Toward High Reproducibility and Accountable Heterogeneity in Schizophrenia Research.	JAMA psychiatry	Kochunov, Peter; Thompson, Paul M; Hong, L Elliot	July 1, 2019	Not Determined
30927318	Create Study	White matter and hypoxic hypobaria in humans.	Human brain mapping	McGuire, Stephen A; Ryan, Meghann C; Sherman, Paul M; Sladky, John H; Rowland, Laura M; Wijtenburg, S Andrea; Hong, L Elliot; Kochunov, Peter V	August 1, 2019	Not Determined
30921760	Create Study	Subcortical structures and cognitive dysfunction in first episode schizophrenia.	Psychiatry research. Neuroimaging	Fan, Fengmei; Xiang, Hong; Tan, Shuping; Yang, Fude; Fan, Hongzhen; Guo, Hua; Kochunov, Peter; Wang, Zhiren; Hong, L Elliot; Tan, Yunlong	April 30, 2019	Not Determined
30914942	Create Study	Homogenizing Estimates of Heritability Among SOLAR-Eclipse, OpenMx, APACE, and FPHI Software Packages in Neuroimaging Data.	Frontiers in neuroinformatics	Kochunov, Peter; Patel, Binish; Ganjgahi, Habib; Donohue, Brian; Ryan, Meghann; Hong, Elliot L; Chen, Xu; Adhikari, Bhim; Jahanshad, Neda; Thompson, Paul M; Van't Ent, Dennis; den Braber, Anouk; de Geus, Eco J C; Brouwer, Rachel M; Boomsma, Dorret I; Hulshoff Pol, Hilleke E; de Zubicaray, Greig I; McMahon, Katie L; Martin, Nicholas G; Wright, Margaret J; Nichols, Thomas E	January 1, 2019	Not Determined
30576563	Create Study	Aberrant Frontostriatal Connectivity in Negative Symptoms of Schizophrenia.	Schizophrenia bulletin	Shukla, Dinesh K; Chiappelli, Joshua John; Sampath, Hemalatha; Kochunov, Peter; Hare, Stephanie M; Wisner, Krista; Rowland, Laura M; Hong, L Elliot	September 11, 2019	Not Determined
30503620	Create Study	Rapid Transformation from Auditory to Linguistic Representations of Continuous Speech.	Current biology : CB	Brodbeck, Christian; Hong, L Elliot; Simon, Jonathan Z	December 17, 2018	Not Determined
30496643	Create Study	Genomic kinship construction to enhance genetic analyses in the human connectome project data.	Human brain mapping	Kochunov, Peter; Donohue, Brian; Mitchell, Braxton D; Ganjgahi, Habib; Adhikari, Bhim; Ryan, Meghann; Medland, Sarah E; Jahanshad, Neda; Thompson, Paul M; Blangero, John; Fieremans, Els; Novikov, Dmitry S; Marcus, Daniel; Van Essen, David C; Glahn, David C; Elliot Hong, L; Nichols, Thomas E	April 1, 2019	Not Determined
30420620	Create Study	Elevated allostatic load early in the course of schizophrenia.	Translational psychiatry	Savransky, Anya; Chiappelli, Joshua; Fisseha, Feven; Wisner, Krista M; Xiaoming, Du; Mirmomen, S Milad; Jones, Aaron D; Adhikari, Bhim M; Bruce, Heather A; Rowland, Laura M; Hong, L Elliot	November 12, 2018	Not Determined
30203093	Create Study	Bayesian modeling of dependence in brain connectivity data.	Biostatistics (Oxford, England)	Chen, Shuo; Xing, Yishi; Kang, Jian; Kochunov, Peter; Hong, L Elliot	April 1, 2020	Not Determined
30191514	Create Study	A resting state fMRI analysis pipeline for pooling inference across diverse cohorts: an ENIGMA rs-fMRI protocol.	Brain imaging and behavior	Adhikari, Bhim M; Jahanshad, Neda; Shukla, Dinesh; Turner, Jessica; Grotegerd, Dominik; Dannlowski, Udo; Kugel, Harald; Engelen, Jennifer; Dietsche, Bruno; Krug, Axel; Kircher, Tilo; Fieremans, Els; Veraart, Jelle; Novikov, Dmitry S; Boedhoe, Premika S W; van der Werf, Ysbrand D; van den Heuvel, Odile A; Ipser, Jonathan; Uhlmann, Anne; Stein, Dan J; Dickie, Erin; Voineskos, Aristotle N; Malhotra, Anil K; Pizzagalli, Fabrizio; Calhoun, Vince D; Waller, Lea; Veer, Ilja M; Walter, Hernik; Buchanan, Robert W; Glahn, David C; Hong, L Elliot; Thompson, Paul M; Kochunov, Peter	October 1, 2019	Not Determined
30150749	Create Study	Decreased Gray Matter Volume of Cuneus and Lingual Gyrus in Schizophrenia Patients with Tardive Dyskinesia is Associated with Abnormal Involuntary Movement.	Scientific reports	Yu, Ting; Li, Yanli; Fan, Fengmei; Cao, Hongbao; Luo, Xingguang; Tan, Shuping; Yang, Fude; Zhang, Xiangyang; Shugart, Yin Yao; Hong, L Elliot; Li, Chiang-Shan R; Tan, Yunlong	August 27, 2018	Not Determined
30126607	Create Study	Aberrant Middle Prefrontal-Motor Cortex Connectivity Mediates Motor Inhibitory Biomarker in Schizophrenia.	Biological psychiatry	Du, Xiaoming; Choa, Fow-Sen; Chiappelli, Joshua; Wisner, Krista M; Wittenberg, George; Adhikari, Bhim; Bruce, Heather; Rowland, Laura M; Kochunov, Peter; Hong, L Elliot	January 1, 2019	Not Determined
30099002	Create Study	Miniature pig magnetic resonance spectroscopy model of normal adolescent brain development.	Journal of neuroscience methods	Ryan, Meghann C; Kochunov, Peter; Sherman, Paul M; Rowland, Laura M; Wijtenburg, S Andrea; Acheson, Ashley; Hong, L Elliot; Sladky, John; McGuire, Stephen	October 1, 2018	Not Determined
30052318	Create Study	Comparison of heritability estimates on resting state fMRI connectivity phenotypes using the ENIGMA analysis pipeline.	Human brain mapping	Adhikari, Bhim M; Jahanshad, Neda; Shukla, Dinesh; Glahn, David C; Blangero, John; Fox, Peter T; Reynolds, Richard C; Cox, Robert W; Fieremans, Els; Veraart, Jelle; Novikov, Dmitry S; Nichols, Thomas E; Hong, L Elliot; Thompson, Paul M; Kochunov, Peter	December 1, 2018	Not Determined
30032068	Create Study	Test-retest reliability of short-interval intracortical inhibition and intracortical facilitation in patients with schizophrenia.	Psychiatry research	Du, Xiaoming; Hong, L Elliot	September 1, 2018	Not Determined
29960671	Create Study	Cortical Brain Abnormalities in 4474 Individuals With Schizophrenia and 5098 Control Subjects via the Enhancing Neuro Imaging Genetics Through Meta Analysis (ENIGMA) Consortium.	Biological psychiatry	van Erp, Theo G M; Walton, Esther; Hibar, Derrek P; Schmaal, Lianne; Jiang, Wenhao; Glahn, David C; Pearlson, Godfrey D; Yao, Nailin; Fukunaga, Masaki; Hashimoto, Ryota; Okada, Naohiro; Yamamori, Hidenaga; Bustillo, Juan R; Clark, Vincent P; Agartz, Ingrid; Mueller, Bryon A; Cahn, Wiepke; de Zwarte, Sonja M C; Hulshoff Pol, Hilleke E; Kahn, René S; Ophoff, Roel A; van Haren, Neeltje E M; Andreassen, Ole A; Dale, Anders M; Doan, Nhat Trung; Gurholt, Tiril P; Hartberg, Cecilie B; Haukvik, Unn K; Jørgensen, Kjetil N; Lagerberg, Trine V; Melle, Ingrid; Westlye, Lars T; Gruber, Oliver; Kraemer, Bernd; Richter, Anja; Zilles, David; Calhoun, Vince D; Crespo-Facorro, Benedicto; Roiz-Santiañez, Roberto; Tordesillas-Gutiérrez, Diana; Loughland, Carmel; Carr, Vaughan J; Catts, Stanley; Cropley, Vanessa L; Fullerton, Janice M; Green, Melissa J; Henskens, Frans A; Jablensky, Assen; Lenroot, Rhoshel K; Mowry, Bryan J; Michie, Patricia T; Pantelis, Christos; Quidé, Yann; Schall, Ulrich; Scott, Rodney J; Cairns, Murray J; Seal, Marc; Tooney, Paul A; Rasser, Paul E; Cooper, Gavin; Shannon Weickert, Cynthia; Weickert, Thomas W; Morris, Derek W; Hong, Elliot; Kochunov, Peter; Beard, Lauren M; Gur, Raquel E; Gur, Ruben C; Satterthwaite, Theodore D; Wolf, Daniel H; Belger, Aysenil; Brown, Gregory G; Ford, Judith M; Macciardi, Fabio; Mathalon, Daniel H; O'Leary, Daniel S; Potkin, Steven G; Preda, Adrian; Voyvodic, James; Lim, Kelvin O; McEwen, Sarah; Yang, Fude; Tan, Yunlong; Tan, Shuping; Wang, Zhiren; Fan, Fengmei; Chen, Jingxu; Xiang, Hong; Tang, Shiyou; Guo, Hua; Wan, Ping; Wei, Dong; Bockholt, Henry J; Ehrlich, Stefan; Wolthusen, Rick P F; King, Margaret D; Shoemaker, Jody M; Sponheim, Scott R; De Haan, Lieuwe; Koenders, Laura; Machielsen, Marise W; van Amelsvoort, Therese; Veltman, Dick J; Assogna, Francesca; Banaj, Nerisa; de Rossi, Pietro; Iorio, Mariangela; Piras, Fabrizio; Spalletta, Gianfranco; McKenna, Peter J; Pomarol-Clotet, Edith; Salvador, Raymond; Corvin, Aiden; Donohoe, Gary; Kelly, Sinead; Whelan, Christopher D; Dickie, Erin W; Rotenberg, David; Voineskos, Aristotle N; Ciufolini, Simone; Radua, Joaquim; Dazzan, Paola; Murray, Robin; Reis Marques, Tiago; Simmons, Andrew; Borgwardt, Stefan; Egloff, Laura; Harrisberger, Fabienne; Riecher-Rössler, Anita; Smieskova, Renata; Alpert, Kathryn I; Wang, Lei; Jönsson, Erik G; Koops, Sanne; Sommer, Iris E C; Bertolino, Alessandro; Bonvino, Aurora; Di Giorgio, Annabella; Neilson, Emma; Mayer, Andrew R; Stephen, Julia M; Kwon, Jun Soo; Yun, Je-Yeon; Cannon, Dara M; McDonald, Colm; Lebedeva, Irina; Tomyshev, Alexander S; Akhadov, Tolibjohn; Kaleda, Vasily; Fatouros-Bergman, Helena; Flyckt, Lena; Karolinska Schizophrenia Project; Busatto, Geraldo F; Rosa, Pedro G P; Serpa, Mauricio H; Zanetti, Marcus V; Hoschl, Cyril; Skoch, Antonin; Spaniel, Filip; Tomecek, David; Hagenaars, Saskia P; McIntosh, Andrew M; Whalley, Heather C; Lawrie, Stephen M; Knöchel, Christian; Oertel-Knöchel, Viola; Stäblein, Michael; Howells, Fleur M; Stein, Dan J; Temmingh, Henk S; Uhlmann, Anne; Lopez-Jaramillo, Carlos; Dima, Danai; McMahon, Agnes; Faskowitz, Joshua I; Gutman, Boris A; Jahanshad, Neda; Thompson, Paul M; Turner, Jessica A	November 1, 2018	Not Determined
29759942	Create Study	TMS evoked N100 reflects local GABA and glutamate balance.	Brain stimulation	Du, Xiaoming; Rowland, Laura M; Summerfelt, Ann; Wijtenburg, Andrea; Chiappelli, Joshua; Wisner, Krista; Kochunov, Peter; Choa, Fow-Sen; Hong, L Elliot	September 1, 2018	Not Determined

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Collection - Publications

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Data Expected List: Mandatory Data Structures

These data structures are mandatory for your NDA Collection. Please update the Targeted Enrollment number to accurately represent the number of subjects you expect to submit for the entire study.

For NIMH HIV-related research that involves human research participants: Select the dictionary or dictionaries most appropriate for your research. If your research does not require all three data dictionaries, just ignore the ones you do not need. There is no need to delete extra data dictionaries from your NDA Collection. You can adjust the Targeted Enrollment column in the Data Expected tab to “0” for those unnecessary data dictionaries. At least one of the three data dictionaries must have a non-zero value.

Data Expected	Targeted Enrollment	Initial Submission	Subjects Submitted	Initial Share	Subjects Shared	Status
Research Subject and Pedigree	210	07/15/2019	211	11/15/2019	211	Approved

To create your project's Data Expected list, use the "+New Data Expected" to add or request existing structures and to request new Data Structures that are not in the NDA Data Dictionary.

If the Structure you need already exists, locate it and specify your dates and enrollment when adding it to your Data Expected list. If you require changes to the Structure you need, select the indicator stating "No, it requires changes to meet research needs," and upload a file containing your requested changes.

If the structure you need is not yet defined in the Data Dictionary, you can select "Upload Definition" and attach the necessary materials to request its creation.

When selecting the expected dates for your data, make sure to follow the standard Data Sharing Regimen and choose dates within the date ranges that correspond to your project start and end dates.

Please visit the Completing Your Data Expected Tutorial for more information.

Data Expected List: Data Structures per Research Aims

These data structures are specific to your research aims and should list all data structures in which data will be collected and submitted for this NDA Collection. Please update the Targeted Enrollment number to accurately represent the number of subjects you expect to submit for the entire study.

Data Expected	Targeted Enrollment	Initial Submission	Subjects Submitted	Initial Share	Subjects Shared	Status
Perceived Stress Scale	210	07/15/2019	211	11/15/2019	211	Approved
Childhood Trauma Questionnaire	210	07/15/2019	211	11/15/2019	211	Approved
Medical History	210	07/15/2019	211	11/15/2019	211	Approved
Physical Exam	210	07/15/2019	211	11/15/2019	211	Approved
Pittsburgh Sleep Quality Index	210	07/15/2019	211	11/15/2019	211	Approved
Brief Psychiatric Rating Scale	210	07/15/2019	211	11/15/2019	211	Approved
Beck Depression Inventory	210	07/15/2019	211	11/15/2019	211	Approved
Fagerstrom Test for Nicotine Dependence	210	07/15/2019	211	11/15/2019	211	Approved
Imaging (Structural, fMRI, DTI, PET, microscopy)	210	07/15/2019	181	11/15/2019	181	Approved
Digit Symbol Substitution Test	210	07/15/2019	211	11/15/2019	211	Approved
Brief Negative Symptom Scale	210	07/15/2019	211	11/15/2019	211	Approved

Structure not yet defined

No Status history for this Data Expected has been recorded yet

helpcenter.collection.data-expected-tab

Collection - Data Expected

The Data Expected tab displays the list of all data that NDA expects to receive in association with the Collection as defined by the contributing researcher, as well as the dates for the expected initial upload of the data, and when it is first expected to be shared, or with the research community. Above the primary table of Data Expected, any publications determined to be relevant to the data within the Collection are also displayed - members of the contributing research group can use these to define NDA Studies, connecting those papers to underlying data in NDA.

The tab is used both as a reference for those accessing shared data, providing information on what is expected and when it will be shared, and as the primary tracking mechanism for contributing projects. It is used by both contributing primary researchers, secondary researchers, and NIH Program and Grants Management staff.

Researchers who are starting their project need to update their Data Expected list to include all the Data Structures they are collecting under their grant and set their initial submission and sharing schedule according to the NDA Data Sharing Regimen.

To add existing Data Structures from the Data Dictionary, to request new Data Structure that are not in the Dictionary, or to request changes to existing Data Structures, click "+New Data Expected".

For step-by-step instructions on how to add existing Data Structures, request changes to an existing Structure, or request a new Data Structure, please visit the Completing Your Data Expected Tutorial.

If you are a contributing researcher creating this list for the first time, or making changes to the list as your project progress, please note the following:

Although items you add to the list and changes you make are displayed, they are not committed to the system until you Save the entire page using the "Save" button at the bottom of your screen. Please Save after every change to ensure none of your work is lost.
If you attempt to add a new structure, the title you provide must be unique - if another structure exists with the same name your change will fail.
Adding a new structure to this list is the only way to request the creation of a new Data Dictionary definition.

Frequently Asked Questions

What is an NDA Data Structure?

An NDA Data Structure is comprised of multiple Data Elements to make up an electronic definition of an assessment, measure, questionnaire, etc will have a corresponding Data Structure.
What is the NDA Data Dictionary?

The NDA Data Dictionary is comprised of electronic definitions known as Data Structures.

Glossary

Analyzed Data

Data specific to the primary aims of the research being conducted (e.g. outcome measures, other dependent variables, observations, laboratory results, analyzed images, volumetric data, etc.) including processed images.
Data Item

Items listed on the Data Expected list in the Collection which may be an individual and discrete Data Structure, Data Structure Category, or Data Structure Group.
Data Structure

A defined organization and group of Data Elements to represent an electronic definition of a measure, assessment, questionnaire, or collection of data points. Data structures that have been defined in the NDA Data Dictionary are available at https://nda.nih.gov/general-query.html?q=query=data-structure
Data Structure Category

An NDA term describing the affiliation of a Data Structure to a Category, which may be disease/disorder or diagnosis related (Depression, ADHD, Psychosis), specific to data type (MRI, eye tracking, omics), or type of data (physical exam, IQ).
Data Structure Group

A Data Item listed on the Data Expected tab of a Collection that indicates a group of Data Structures (e.g., ADOS or SCID) for which data may be submitted instead of a specific Data Structure identified by version, module, edition, etc. For example, the ADOS Data Structure Category includes every ADOS Data Structure such as ADOS Module 1, ADOS Module 2, ADOS Module 1 - 2nd Edition, etc. The SCID Data Structure Group includes every SCID Data Structure such as SCID Mania, SCID V Mania, SCID PTSD, SCID-V Diagnosis, and more.
Evaluated Data

A new Data Structure category, Evaluated Data is analyzed data resulting from the use of computational pipelines in the Cloud and can be uploaded directly back to a miNDAR database. Evaluated Data is expected to be listed as a Data Item in the Collection's Data Expected Tab.
Imaging Data

Imaging+ is an NDA term which encompasses all imaging related data including, but not limited to, images (DTI, MRI, PET, Structural, Spectroscopy, etc.) as well as neurosignal data (EEG, fMRI, MEG, EGG, eye tracking, etc.) and Evaluated Data.
Initial Share Date

Initial Submission and Initial Share dates should be populated according to the NDA Data Sharing Terms and Conditions. Any modifications to these will go through the approval processes outlined above. Data will be shared with authorized users upon publication (via an NDA Study) or 1-2 years after the grant end date specified on the first Notice of Award, as defined in the applicable Data Sharing Terms and Conditions.
Initial Submission Date

Initial Submission and Initial Share dates should be populated according to these NDA Data Sharing Terms and Conditions. Any modifications to these will go through the approval processes outlined above. Data for all subjects is not expected on the Initial Submission Date and modifications may be made as necessary based on the project's conduct.
Research Subject and Pedigree

An NDA created Data Structure used to convey basic information about the subject such as demographics, pedigree (links family GUIDs), diagnosis/phenotype, and sample location that are critical to allow for easier querying of shared data.
Submission Cycle

The NDA has two Submission Cycles per year - January 15 and July 15.
Submission Exemption

An interface to notify NDA that data may not be submitted during the upcoming/current submission cycle.

Contact NDA Help Desk

Collection Owners and those with Collection Administrator permission, may edit a collection. The following is currently available for Edit on this page:

Associated Studies

Studies that have been defined using data from a Collection are important criteria to determine the value of data shared. The number of subjects column displays the counts from this Collection that are included in a Study, out of the total number of subjects in that study. The Data Use column represents whether or not the study is a primary analysis of the data or a secondary analysis. State indicates whether the study is private or shared with the research community.

Study NameFilter by Study Name	AbstractFilter by Abstract	Collection/Study SubjectsFilter by Collection/Study Subjects	Data UsageFilter by Data Usage	StateFilter by State
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helpcenter.collection.associated-studies-tab

Collection - Associated Studies

Clicking on the Study Title will open the study details in a new internet browser tab. The Abstract is available for viewing, providing the background explanation of the study, as provided by the Collection Owner.

Primary v. Secondary Analysis: The Data Usage column will have one of these two choices. An associated study that is listed as being used for Primary Analysis indicates at least some and potentially all of the data used was originally collected by the creator of the NDA Study. Secondary Analysis indicates the Study owner was not involved in the collection of data, and may be used as supporting data.

Private v. Shared State: Studies that remain private indicate the associated study is only available to users who are able to access the collection. A shared study is accessible to the general public.

Frequently Asked Questions

How do I associate a study to my collection?

Studies are associated to the Collection automatically when the data is defined in the Study.

Glossary

Associated Studies Tab

A tab in a Collection that lists the NDA Studies that have been created using data from that Collection including both Primary and Secondary Analysis NDA Studies.

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Frequently Asked Questions

Glossary