NIMH Data Archive - Data

Genomics

Neuroimaging

Phenotype¹

New Trial
Clinical Trial

¹ Numbers reported are subjects by age

New Project
Grant/Project Number

Format should be in the following format: Activity Code, Institute Abbreviation, and Serial Number. Grant Type, Support Year, and Suffix should be excluded. For example, grant 1R01MH123456-01A1 should be entered R01MH123456

Collection - Use Existing Experiment

To associate an experiment to the current collection, just select an axperiment from the table below then click the associate experiment button to persist your changes (saving the collection is not required). Note that once an experiment has been associated to two or more collections, the experiment will not longer be editable.

The table search feature is case insensitive and targets the experiment id, experiment name and experiment type columns. The experiment id is searched only when the search term entered is a number, and filtered using a startsWith comparison. When the search term is not numeric the experiment name is used to filter the results.

Select	Experiment Id	Experiment Name	Experiment Type	Created On

24	HI-NGS_R1	Omics	02/16/2011
475	MB1-10 (CHOP)	Omics	06/07/2016
490	Discovery and CRISPR validation of genetic factors associated with antipsychotic-induced weight gain and cardiometabolic risk	Omics	07/07/2016
501	PharmacoBOLD Resting State	fMRI	07/27/2016
506	PVPREF	Omics	08/05/2016
509	ABC-CT Resting v2	EEG	08/18/2016
13	Comparison of FI expression in Autistic and Neurotypical Homo Sapiens	Omics	12/28/2010
18	AGRE/Broad Affymetrix 5.0 Genotype Experiment	Omics	01/06/2011
22	Stitching PCR Sequencing	Omics	02/14/2011
26	ASD_Methylation	Omics	03/01/2011
29	Microarray family 03 (father, mother, sibling)	Omics	03/24/2011
37	Standard paired-end sequencing of BCRs	Omics	04/19/2011
38	Illumina Mate-Pair BCR sequencing	Omics	04/19/2011
39	Custom Jumping Libraries	Omics	04/19/2011
40	Custom CapBP	Omics	04/19/2011
41	Immunofluorescence	Omics	05/11/2011
43	Autism brain sample genotyping, Illumina	Omics	05/16/2011
47	ARRA Autism Sequencing Collaboration at Baylor. SOLiD 4 System	Omics	08/01/2011
53	AGRE Omni1-quad	Omics	10/11/2011
59	AGP genotyping	Omics	04/03/2012
60	Ultradeep 454 sequencing of synaptic genes from postmortem cerebella of individuals with ASD and neurotypical controls	Omics	06/23/2012
63	Microemulsion PCR and Targeted Resequencing for Variant Detection in ASD	Omics	07/20/2012
76	Whole Genome Sequencing in Autism Families	Omics	01/03/2013
519	Resting	fMRI	11/08/2016
90	Genotyped IAN Samples	Omics	07/09/2013
91	NJLAGS Axiom Genotyping Array	Omics	07/16/2013
93	AGP genotyping (CNV)	Omics	09/06/2013
106	Longitudinal Sleep Study. H20 200. Channel set 2	EEG	11/07/2013
107	Longitudinal Sleep Study. H20 200. Channel set 3	EEG	11/07/2013
108	Longitudinal Sleep Study. AURA 200	EEG	11/07/2013
105	Longitudinal Sleep Study. H20 200. Channel set 1	EEG	11/07/2013
109	Longitudinal Sleep Study. AURA 400	EEG	11/07/2013
116	Gene Expression Analysis WG-6	Omics	01/07/2014
131	Jeste Lab UCLA ACEii: Charlie Brown and Sesame Street - Project 1	Eye Tracking	02/27/2014
132	Jeste Lab UCLA ACEii: Animacy - Project 1	Eye Tracking	02/27/2014
133	Jeste Lab UCLA ACEii: Mom Stranger - Project 2	Eye Tracking	02/27/2014
134	Jeste Lab UCLA ACEii: Face Emotion - Project 3	Eye Tracking	02/27/2014
145	AGRE/FMR1_Illumina.JHU	Omics	04/14/2014
146	AGRE/MECP2_Sanger.JHU	Omics	04/14/2014
147	AGRE/MECP2_Junior.JHU	Omics	04/14/2014
151	Candidate Gene Identification in familial Autism	Omics	06/09/2014
152	NJLAGS Whole Genome Sequencing	Omics	07/01/2014
154	Math Autism Study - Vinod Menon	fMRI	07/15/2014
155	Resting	fMRI	07/25/2014
156	Speech	fMRI	07/25/2014
159	Emotion	fMRI	07/25/2014
160	syllable contrast	EEG	07/29/2014
167	School-age naturalistic stimuli	Eye Tracking	09/19/2014
44	AGRE/Broad Affymetrix 5.0 Genotype Experiment	Omics	06/27/2011
45	Exome Sequencing of 20 Sporadic Cases of Autism Spectrum Disorder	Omics	07/15/2011

Collection - Add Experiment

Add Supporting Documentation

Funding Source:
URL:

To add an existing Data Structure, enter its title in the search bar. If you need to request changes, select the indicator "No, it requires changes to meet research needs" after selecting the Structure, and upload the file with the request changes specific to the selected Data Structure. Your file should follow the Request Changes Procedure. If the Data Structure does not exist, select "Request New Data Structure" and upload the appropriate zip file.

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Please confirm that you will not be enrolling any more subjects and that all raw data has been collected and submitted.

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Your Collection is now in Data Analysis phase and exempt from biannual submissions. Analyzed data is still expected prior to publication or no later than the project end date.

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You have requested to move the sharing dates for the following assessments:

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Acute Neurocognitive-affective Predictors of Chronic Post-trauma Outcomes #2297

General
Experiments (12)
Shared Data
Publications (52)
Data Expected (37)
Associated Studies (0)

Collection Title	Collection Investigators	Collection Description
Collection Title:	Acute Neurocognitive-affective Predictors of Chronic Post-trauma Outcomes
Collection Investigators:	Christine Larson
Collection Description:	Trauma exposure is extremely common and increases risk for a host of negative health outcomes, most notably posttraumatic stress disorder (PTSD). Given the potential harmful sequelae of trauma exposure, it is crucial to identify acute post-trauma risk factors that predict chronic PTSD and other poor post-trauma outcomes. While some progress has been made in this effort, attempts to identify recently traumatized individuals at risk for poor long-term post-trauma adjustment have proven difficult. In this project we aim to identify predictors of both acute and chronic posttrauma symptoms, and more importantly, identify acute post-trauma measures that predict chronic PTSD, as well as other syndromes including depression and substance use problems. We will assess the predictive utility of three processes that are 1) rooted in basic cognitive and affective neuroscience, 2) articulated in the RDoC matrix, 3) map directly onto established interventions, and 4) show promise in our preliminary data. Leveraging our unique access to the large patient population in the Level 1 trauma service at the Medical College of Wisconsin, we will conduct multi-level (neural circuits, physiology, behavior, self-report) longitudinal assessments of posttrauma and other symptoms, and RDoC-based predictors of these symptoms. Within two weeks of trauma exposure we will assess RDoC-based indices of processes hypothesized to increase posttraumatic stress symptoms, including extinction and retention of extinction of conditioned fear (Acute Threat/Fear, Sustained Threat), impaired filtering of threat (Attentional Control), and attentional bias to threat (Sustained Threat). At six months post-exposure we will again conduct multilevel assessments of these processes and measure symptoms of PTSD and other relevant syndromes. In addition to these two primary assessment points (both involving neuroimaging), we will also collect a battery indexing cognitive and affective functioning and symptom severity at multiple points up to 24 months post-exposure. We will scan 220 individuals, oversampled for acute posttrauma symptoms, at 2 weeks with the goal of a final six-month sample of 200, and a final 24-month sample of 150. We hypothesize that acute impairments in fear extinction, extinction related plasticity (changes in resting state functional connectivity from before to after extinction), attentional filtering, and attentional bias will predict elevated PTSD symptoms six to twenty-four months post-exposure. This work offers several key innovations: 1) longitudinal multi-level assessment of acutely traumatized patients, 2) the use of neural measures to predict long-term outcomes, 3) the use of a novel paradigm to assess extinction-induced plasticity, and 4) the combination of extinction and attention, two core mechanisms hypothesized to increase risk for PTSD, in the same sample. We expect this project to further the NIMH mission through the use of RDoC indices grounded in basic science, translated to clinical indicators, and directly linked to empirically-determined interventions. Findings from this work will provide new knowledge aiding early identification of trauma-exposed individuals most-at risk for chronic PTSD, and potentially targets for early intervention.
Data Repository:	NIMH Data Archive
Permission Group:
Collection Creation Date:	08/19/2015
Collection Phase:	Funding Completed
Collection Sub-Phase:	Close Out
Blinded Clinical Trial:	No
Total Funded Amount:	$3,074,715.00
Subjects Shared:	233
Collection DOI:	10.15154/3dz2-5g25

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Funding Sources:

Funding Source Name	Funding Source URL
NIH - Extramural	None

Supporting Documentation:

File Name	File Type	Description	Audience
NIMH Note to Remove RDoCdb Data.docx	Software	Note to Remove Data	Qualified Researchers
QA-notification.txt	Other	Quality Assurance Notification	Qualified Researchers

Grant Information:

Project Number	Title	Start Date	Original End Date	End Date	Planned Enrollment	Actual Enrollment	Organization	Funds Obligated
R01MH106574-01	Acute Neurocognitive-affective Predictors of Chronic Post-trauma Outcomes	08/01/2015	05/31/2020	05/31/2020	220	232	UNIVERSITY OF WISCONSIN MILWAUKEE	$3,074,715.00

Clinical Trials:

helpcenter.collection.general-tab

Collection - General Tab

Fields available for edit on the top portion of the page include:

Collection Title
Investigators
Collection Description
Collection Phase
Funding Source
Clinical Trials

Collection Phase: The current status of a research project submitting data to an NDA Collection, based on the timing of the award and/or the data that have been submitted.

Pre-Enrollment: The default entry made when the NDA Collection is created.
Enrolling: Data have been submitted to the NDA Collection or the NDA Data Expected initial submission date has been reached for at least one data structure category in the NDA Collection.
Data Analysis: Subject level data collection for the research project is completed and has been submitted to the NDA Collection. The NDA Collection owner or the NDA Help Desk may set this phase when they’ve confirmed data submission is complete and submitted subject counts match at least 90% of the target enrollment numbers in the NDA Data Expected. Data submission reminders will be turned off for the NDA Collection.
Funding Completed: The NIH grant award (or awards) associated with the NDA Collection has reached its end date. NDA Collections in Funding Completed phase are assigned a subphase to indicate the status of data submission.
- The Data Expected Subphase indicates that NDA expects more data will be submitted
- The Closeout Subphase indicates the data submission is complete.
- The Sharing Not Met Subphase indicates that data submission was not completed as expected.

Blinded Clinical Trial Status:

This status is set by a Collection Owner and indicates the research project is a double blinded clinical trial. When selected, the public view of Data Expected will show the Data Expected items and the Submission Dates, but the targeted enrollment and subjects submitted counts will not be displayed.
Targeted enrollment and subjects submitted counts are visible only to NDA Administrators and to the NDA Collection or as the NDA Collection Owner.
When an NDA Collection that is flagged Blinded Clinical Trial reaches the maximum data sharing date for that Data Repository (see https://nda.nih.gov/nda/sharing-regimen.html), the embargo on Data Expected information is released.

Funding Source

The organization(s) responsible for providing the funding is listed here.

Supporting Documentation

Users with Submission privileges, as well as Collection Owners, Program Officers, and those with Administrator privileges, may upload and attach supporting documentation. By default, supporting documentation is shared to the general public, however, the option is also available to limit this information to qualified researchers only.

Grant Information

Identifiable details are displayed about the Project of which the Collection was derived from. You may click in the Project Number to view a full report of the Project captured by the NIH.

Clinical Trials

Any data that is collected to support or further the research of clinical studies will be available here. Collection Owners and those with Administrator privileges may add new clinical trials.

Frequently Asked Questions

How does the NIMH Data Archive (NDA) determine which Permission Group data are submitted into?

During Collection creation, NDA staff determine the appropriate Permission Group based on the type of data to be submitted, the type of access that will be available to data access users, and the information provided by the Program Officer during grant award.
How do I know when a NDA Collection has been created?

When a Collection is created by NDA staff, an email notification will automatically be sent to the PI(s) of the grant(s) associated with the Collection to notify them.
Is a single grant number ever associated with more than one Collection?

The NDA system does not allow for a single grant to be associated with more than one Collection; therefore, a single grant will not be listed in the Grant Information section of a Collection for more than one Collection.
Why is there sometimes more than one grant included in a Collection?

In general, each Collection is associated with only one grant; however, multiple grants may be associated if the grant has multiple competing segments for the same grant number or if multiple different grants are all working on the same project and it makes sense to hold the data in one Collection (e.g., Cooperative Agreements).

Glossary

Administrator Privilege

A privilege provided to a user associated with an NDA Collection or NDA Study whereby that user can perform a full range of actions including providing privileges to other users.
Collection Owner

Generally, the Collection Owner is the contact PI listed on a grant. Only one NDA user is listed as the Collection owner. Most automated emails are primarily sent to the Collection Owner.
Collection Phase
The Collection Phase provides information on data submission as opposed to grant/project completion so while the Collection phase and grant/project phase may be closely related they are often different. Collection users with Administrative Privileges are encouraged to edit the Collection Phase. The Program Officer as listed in eRA (for NIH funded grants) may also edit this field. Changes must be saved by clicking the Save button at the bottom of the page. This field is sortable alphabetically in ascending or descending order. Collection Phase options include:
- Pre-Enrollment: A grant/project has started, but has not yet enrolled subjects.
- Enrolling: A grant/project has begun enrolling subjects. Data submission is likely ongoing at this point.
- Data Analysis: A grant/project has completed enrolling subjects and has completed all data submissions.
- Funding Completed: A grant/project has reached the project end date.
Collection Title

An editable field with the title of the Collection, which is often the title of the grant associated with the Collection.
Grant

Provides the grant number(s) for the grant(s) associated with the Collection. The field is a hyperlink so clicking on the Grant number will direct the user to the grant information in the NIH Research Portfolio Online Reporting Tools (RePORT) page.
Supporting Documentation

Various documents and materials to enable efficient use of the data by investigators unfamiliar with the project and may include the research protocol, questionnaires, and study manuals.
NIH Research Initiative

NDA Collections may be organized by scientific similarity into NIH Research Initiatives, to facilitate query tool user experience. NIH Research Initiatives map to one or multiple Funding Opportunity Announcements.
Permission Group

Access to shared record-level data in NDA is provisioned at the level of a Permission Group. NDA Permission Groups consist of one or multiple NDA Collections that contain data with the same subject consents.
Planned Enrollment

Number of human subject participants to be enrolled in an NIH-funded clinical research study. The data is provided in competing applications and annual progress reports.
Actual Enrollment

Number of human subjects enrolled in an NIH-funded clinical research study. The data is provided in annual progress reports.
NDA Collection

A virtual container and organization structure for data and associated documentation from one grant or one large project/consortium. It contains tools for tracking data submission and allows investigators to define a wide array of other elements that provide context for the data, including all general information regarding the data and source project, experimental parameters used to collect any event-based data contained in the Collection, methods, and other supporting documentation. They also allow investigators to link underlying data to an NDA Study, defining populations and subpopulations specific to research aims.
Data Use Limitations

Data Use Limitations (DULs) describe the appropriate secondary use of a dataset and are based on the original informed consent of a research participant. NDA only accepts consent-based data use limitations defined by the NIH Office of Science Policy.
Total Subjects Shared

The total number of unique subjects for whom data have been shared and are available for users with permission to access data.

Contact NDA Help Desk

ID	Name	Created Date	Status	Type
614	Stop Signal	02/10/2017	Approved	fMRI
620	Emotional Stroop	02/23/2017	Approved	fMRI
621	Fear Conditioning Acquisition	02/23/2017	Approved	fMRI
623	Fear Conditioning Extinction	02/24/2017	Approved	fMRI
624	Fear Conditioning Recall	02/28/2017	Approved	fMRI
625	Imagery Neutral Script	02/28/2017	Approved	fMRI
626	Imagery Trauma Script	02/28/2017	Approved	fMRI
627	Rest	02/28/2017	Approved	fMRI
628	Uncertainty	02/28/2017	Approved	fMRI
632	Picture Viewing Task	03/06/2017	Approved	Eye Tracking
646	Dot-Probe Task (500ms version)	04/11/2017	Approved	Eye Tracking
647	Dot-Probe Task (1,000ms version)	04/11/2017	Approved	Eye Tracking

helpcenter.collection.experiments-tab

Collection - Experiments

The number of Experiments included is displayed in parentheses next to the tab name. You may download all experiments associated with the Collection via the Download button. You may view individual experiments by clicking the Experiment Name and add them to the Filter Cart via the Add to Cart button.

Collection Owners, Program Officers, and users with Submission or Administrative Privileges for the Collection may create or edit an Experiment.

Please note: The creation of an NDA Experiment does not necessarily mean that data collected, according to the defined Experiment, has been submitted or shared.

Frequently Asked Questions

Can an Experiment be associated with more than one Collection?
Yes -see the “Copy” button in the bottom left when viewing an experiment. There are two actions that can be performed via this button:
1. Copy the experiment with intent for modifications.
2. Associate the experiment to the collection. No modifications can be made to the experiment.

Glossary

Experiment Status

An Experiment must be Approved before data using the associated Experiment_ID may be uploaded.
Experiment ID

The ID number automatically generated by NDA which must be included in the appropriate file when uploading data to link the Experiment Definition to the subject record.

Contact NDA Help Desk

Shared Data:

Title	Type	Number of Subjects
Alcohol and Drug Use Disorders Identification Test	Clinical Assessments	221
Belief in Just World	Clinical Assessments	215
Centrality of Event Scale	Clinical Assessments	190
Childhood Trauma Questionnaire	Clinical Assessments	214
Crisis in Family Systems	Clinical Assessments	170
Demographics Form Trauma Study	Clinical Assessments	220
Depression, Anxiety, and Stress Scale	Clinical Assessments	221
Drug Abuse Screening Test	Clinical Assessments	221
Drug Screen	Clinical Assessments	224
Emotion Dysregulation Scale	Clinical Assessments	221
Image	Imaging	167
Injustices Experiences Questionnaire	Clinical Assessments	215
Insomnia Severity Index	Clinical Assessments	221
Intolerance of Uncertainty Scale	Clinical Assessments	215
Life Events Checklist	Clinical Assessments	221
Medical Outcomes Study (MOS) Social Support Survey	Clinical Assessments	215
Mild Traumatic Brain Injury Screening	Clinical Assessments	229
Mini IPIP	Clinical Assessments	212
Mini International Neuropsychiatric Interview. Part I	Clinical Assessments	195
Multigroup Ethnic Identity Measure	Clinical Assessments	215
PTSD Checklist - Civilian	Clinical Assessments	219
PTSD Prediction Form	Clinical Assessments	229
PTSD Scale for DSM-5	Clinical Assessments	192
Perceived Ethnic Discrimination Questionnaire	Clinical Assessments	221
Perceived Injury Severity	Clinical Assessments	229
Peritraumatic Distress Inventory	Clinical Assessments	229
Research Subject	Clinical Assessments	228
SF-36 Health Survey	Clinical Assessments	201
Sheehan Disability Scales	Clinical Assessments	221
Snaith-Hamilton Pleasure Scale	Clinical Assessments	218
State-Trait Anger Expression Inventory	Clinical Assessments	221
State-Trait Anxiety Inventory for Adults	Clinical Assessments	215
Subtypes of Antisocial Behavior	Clinical Assessments	190
Trauma Neutral Script	Clinical Assessments	166
Trauma Quality of Life Measure	Clinical Assessments	200
Vitals Assessment	Clinical Assessments	229
WebNeuro	Clinical Assessments	216

helpcenter.collection.shared-data-tab

Collection - Shared Data

This tab provides a quick overview of the Data Structure title, Data Type, and Number of Subjects that are currently Shared for the Collection. The information presented in this tab is automatically generated by NDA and cannot be edited. If no information is visible on this tab, this would indicate the Collection does not have shared data or the data is private.

The shared data is available to other researchers who have permission to access data in the Collection's designated Permission Group(s). Use the Download button to get all shared data from the Collection to the Filter Cart.

Frequently Asked Questions

How will I know if another researcher uses data that I shared through the NIMH Data Archive (NDA)?

To see what data your project have submitted are being used by a study, simply go the Associated Studies tab of your collection. Alternatively, you may review an NDA Study Attribution Report available on the General tab.
Can I get a supplement to share data from a completed research project?

Often it becomes more difficult to organize and format data electronically after the project has been completed and the information needed to create a GUID may not be available; however, you may still contact a program staff member at the appropriate funding institution for more information.
Can I get a supplement to share data from a research project that is still ongoing?

Unlike completed projects where researchers may not have the information needed to create a GUID and/or where the effort needed to organize and format data becomes prohibitive, ongoing projects have more of an opportunity to overcome these challenges. Please contact a program staff member at the appropriate funding institution for more information.

Glossary

Data Structure

A defined organization and group of Data Elements to represent an electronic definition of a measure, assessment, questionnaire, or collection of data points. Data structures that have been defined in the NDA Data Dictionary are available at https://nda.nih.gov/general-query.html?q=query=data-structure
Data Type

A grouping of data by similar characteristics such as Clinical Assessments, Omics, or Neurosignal data.
Shared

The term 'Shared' generally means available to others; however, there are some slightly different meanings based on what is Shared. A Shared NDA Study is viewable and searchable publicly regardless of the user's role or whether the user has an NDA account. A Shared NDA Study does not necessarily mean that data used in the NDA Study have been shared as this is independently determined. Data are shared according the schedule defined in a Collection's Data Expected Tab and/or in accordance with data sharing expectations in the NDA Data Sharing Terms and Conditions. Additionally, Supporting Documentation uploaded to a Collection may be shared independent of whether data are shared.

Contact NDA Help Desk

Collection Owners and those with Collection Administrator permission, may edit a collection. The following is currently available for Edit on this page:

Publications

Publications relevant to NDA data are listed below. Most displayed publications have been associated with the grant within Pubmed. Use the "+ New Publication" button to add new publications. Publications relevant/not relevant to data expected are categorized. Relevant publications are then linked to the underlying data by selecting the Create Study link. Study provides the ability to define cohorts, assign subjects, define outcome measures and lists the study type, data analysis and results. Analyzed data and results are expected in this way.

PubMed ID	Study	Title	Journal	Authors	Date	Status
41675656	Create Study	Mental Health Disparities Following Violent Injury: A Prospective Comparison of Survivors of Violent and Nonviolent Mechanisms of Injury.	Panamerican journal of trauma, critical care & emergency surgery	Timmer-Murillo, Sydney C; Tomas, Carissa W; Geier, Timothy J; Melin, Sarah; Brandolino, Amber; Schramm, Andrew T; Larson, Christine L; deRoon-Cassini, Terri A	January 1, 2024	Not Determined
41605128	Create Study	PTSD symptoms and substance use problems in traumatic injury patients: A 24-month follow-up.	Addictive behaviors	Fendrich, Michael; Petranu, Kevin; Nickel, Lauren; Larson, Christine L; deRoon-Cassini, Terri A	April 1, 2026	Not Determined
41138791	Create Study	Image-based meta- and mega-analysis (IBMMA): A unified framework for large-scale, multi-site, neuroimaging data analysis.	NeuroImage	Steele, Nick; Huggins, Ashley A; Morey, Rajendra A; Hussain, Ahmed; Russell, Courtney; Suarez-Jimenez, Benjamin; Pozzi, Elena; Jameei, Hadis; Schmaal, Lianne; Veer, Ilya M; Waller, Lea; Jahanshad, Neda; Thomopoulos, Sophia I; Salminen, Lauren E; Olff, Miranda; Frijling, Jessie L; Veltman, Dick J; Koch, Saskia B J; Nawijn, Laura; van Zuiden, Mirjam; Wang, Li; Zhu, Ye; Li, Gen; Stein, Dan J; Ipser, Jonathan; Neria, Yuval; Zhu, Xi; Ravid, Orren; Zilcha-Mano, Sigal; Lazarov, Amit; Stevens, Jennifer S; Ressler, Kerry; Jovanovic, Tanja; van Rooij, Sanne J H; Fani, Negar; Mueller, Sven C; Hudson, Anna R; Daniels, Judith K; Sierk, Anika; Manthey, Antje; Walter, Henrik; van der Wee, Nic J A; van der Werff, Steven J A; Vermeiren, Robert R J M; Schmahl, Christian; Herzog, Julia I; Rektor, Ivan; Říha, Pavel; Kaufman, Milissa L; Lebois, Lauren A M; Baker, Justin T; Rosso, Isabelle M; Olson, Elizabeth A; King, Anthony; Liberzon, Israel; Angstadt, Michael; Davenport, Nicholas D; Disner, Seth G; Sponheim, Scott R; Straube, Thomas; Hofmann, David; Lu, Guangming; Qi, Rongfeng; Wang, Xin; Kunch, Austin; Xie, Hong; Quidé, Yann; El-Hage, Wissam; Lissek, Shmuel; Berg, Hannah; Bruce, Steven E; Cisler, Josh; Ross, Marisa; Herringa, Ryan J; Grupe, Daniel W; Nitschke, Jack B; Davidson, Richard J; Larson, Christine; deRoon-Cassini, Terri A; Tomas, Carissa W; Fitzgerald, Jacklynn M; Elman, Jeremy; Panizzon, Matthew; Franz, Carol E; Lyons, Michael J; Kremen, William S; Feola, Brandee; Blackford, Jennifer U; Olatunji, Bunmi O; May, Geoffrey; Nelson, Steven M; Gordon, Evan M; Abdallah, Chadi G; Lanius, Ruth; Densmore, Maria; Théberge, Jean; Neufeld, Richard W J; Thompson, Paul M; Sun, Delin	November 15, 2025	Not Determined
40849409	Create Study	Neural correlates of human fear conditioning and sources of variability in 2199 individuals.	Nature communications	Radua, Joaquim; Savage, Hannah S; Vilajosana, Enric; Jamieson, Alec; Abler, Birgit; Åhs, Fredrik; Beckers, Tom; Cardoner, Narcís; Cisler, Josh M; Diniz, Juliana B; Bach, Dominik R; Elsenbruch, Sigrid; Greening, Steven G; Holt, Daphne J; Kaczkurkin, Antonia N; Keil, Andreas; Kindt, Merel; Koch, Kathrin; LaBar, Kevin S; Lam, Charlene L; Larson, Christine L; Lonsdorf, Tina B; Merz, Christian J; McLaughlin, Katie A; Neria, Yuval; Pine, Daniel S; van Reekum, Carien M; Shackman, Alexander J; Soriano-Mas, Carles; Spoormaker, Victor I; Stout, Daniel M; Straube, Benjamin; Straube, Thomas; Tuominen, Lauri; Visser, Renée M; Ahumada, Laura; Arolt, Volker; Batistuzzo, Marcelo C; Bazán, Paulo R; Biggs, Emma E; Cano, Marta; Chavarría-Elizondo, Pamela; Cooper, Samuel E; Dannlowski, Udo; de la Peña-Arteaga, Víctor; DeCross, Stephanie N; Domschke, Katharina; Ehlers, Mana R; Graner, John L; Hamm, Alfons O; Herrmann, Martin J; Huggins, Ashley A; Icenhour, Adriane; Juaneda-Seguí, Asier; Junghoefer, Markus; Kircher, Tilo; Koelkebeck, Katja; Kuhn, Manuel; Labrenz, Franziska; Lissek, Shmuel M; Lotze, Martin; Lueken, Ulrike; Margraf, Jürgen; Martínez-Zalacaín, Ignacio; Moeck, Robert; Morriss, Jayne; Ortuño, María; Pittig, Andre; Porta-Casteras, Daniel; Richter, Jan; Ridderbusch, Isabelle C; Rief, Winfried; Roesmann, Kati; Rosén, Jörgen; Rußmann, Alena N; Sjouwerman, Rachel; Spohrs, Jennifer; Ströhle, Andreas; Suarez-Jimenez, Benjamin; Ulrich, Martin; Wittchen, Hans-Ulrich; Zhu, Xi; Waller, Lea; Walter, Henrik; Thompson, Paul M; Bas-Hoogendam, Janna Marie; Groenewold, Nynke A; J Stein, Dan; Van der Wee, Nic J; Dunsmoor, Joseph E; Marquand, Andre F; J Harrison, Ben; Fullana, Miquel A	August 23, 2025	Not Determined
40736265	Create Study	Data-Driven Approach to Dynamic Resting State Functional Connectivity in Post-Traumatic Stress Disorder: An ENIGMA-PGC PTSD Study.	Human brain mapping	Tomas, Carissa W; Fitzgerald, Jacklynn M; Baird, C Lexi; Haswell, Courtney C; Abdallah, Chadi G; Angstadt, Michael; Baker, Justin T; Berg, Hannah; Blackford, Jennifer U; Cisler, Josh; Cotton, Andrew S; Daniels, Judith K; Davenport, Nicholas D; Davidson, Richard J; deRoon-Cassini, Terri A; Disner, Seth G; El Hage, Wissam; Fani, Negar; Frijling, Jessie L; Gordon, Evan M; Grupe, Daniel W; He, Xiaofu; Herringa, Ryan; Hofmann, David; Huggins, Ashley A; Hussain, Ahmed; Ipser, Jonathan; Jahanshad, Neda; Jovanovic, Tanja; Kaufman, Milissa L; Kim, Yoojean; King, Anthony; Koch, Saskia B J; Koopowitz, Sheri; Lazarov, Amit; Lebois, Lauren A M; Liberzon, Isreal; Lissek, Shmuel; Manthey, Antje; May, Geoffrey; McLaughlin, Katie A; Nawijn, Laura; Nelson, Steven M; Neria, Yuval; Nitschke, Jack B; Olatunji, Bunmi O; Olff, Miranda; Peverill, Matthew; Quidé, Yann; Ravid, Orren; Ressler, Kerry; Ross, Marisa; Salminen, Lauren E; Sambrook, Kelly; Shih, Chiahao; Sierk, Anika; Sponheim, Scott R; Stein, Dan J; Stevens, Jennifer; Straube, Thomas; Suarez-Jimenez, Benjamin; Thompson, Paul M; van der Wee, Nic J A; van der Werff, Steven J A; van Rooij, Sanne J H; van Zuiden, Mirjam; Veltman, Dick J; Vermeiren, Robert R J M; Walter, Henrik; Wang, Xin; Xie, Hong; Zhu, Xi; Zilcha-Mano, Sigal; Larson, Christine L; Morey, Rajendra	August 1, 2025	Not Determined
40712699	Create Study	Structural Covariance of Early Visual Cortex Is Negatively Associated With Posttraumatic Stress Disorder Symptoms: A Mega-Analysis From the ENIGMA PTSD Working Group.	Biological psychiatry. Cognitive neuroscience and neuroimaging	Harnett, Nathaniel G; Joshi, Soumyaa; Kumar, Poornima; Russell, Courtney; Dillon, Daniel G; Baker, Justin T; Pizzagalli, Diego A; Kaufman, Milissa L; Nickerson, Lisa D; Jahanshad, Neda; Salminen, Lauren E; Thomopoulos, Sophia I; Frijling, Jessie L; Veltman, Dick J; Koch, Saskia B J; Nawijn, Laura; van Zuiden, Mirjam; Zhu, Ye; Li, Gen; Ipser, Jonathan; Zhu, Xi; Ravid, Orren; Zilcha-Mano, Sigal; Lazarov, Amit; Suarez-Jimenez, Benjamin; Sun, Delin; Hussain, Ahmed; Huggins, Ashley A; Jovanovic, Tanja; van Rooij, Sanne J H; Fani, Negar; Hudson, Anna R; Sierk, Anika; Manthey, Antje; Walter, Henrik; van der Wee, Nic J A; van der Werff, Steven J A; Vermeiren, Robert R J M; Říha, Pavel; Lebois, Lauren A M; Rosso, Isabelle M; Olson, Elizabeth A; Liberzon, Israel; Angstadt, Mike; Disner, Seth G; Sponheim, Scott R; Koopowitz, Sheri-Michelle; Hofmann, David; Qi, Rongfeng; Maron-Katz, Adi; Kunch, Austin; Xie, Hong; El-Hage, Wissam; Berg, Hannah; Bruce, Steven E; McLaughlin, Katie A; Peverill, Matthew; Sambrook, Kelly; Ross, Marisa; Herringa, Ryan J; Nitschke, Jack B; Davidson, Richard J; deRoon-Cassini, Terri A; Tomas, Carissa W; Fitzgerald, Jacklynn M; Blackford, Jennifer Urbano; Olatunji, Bunmi O; Nelson, Steven M; Gordon, Evan M; Densmore, Maria; Théberge, Jean; Neufeld, Richard W J; Olff, Miranda; Wang, Li; Stein, Dan J; Neria, Yuval; Stevens, Jennifer S; Mueller, Sven C; Daniels, Judith K; Rektor, Ivan; King, Anthony; Davenport, Nicholas D; Straube, Thomas; Lu, Guangming; Etkin, Amit; Wang, Xin; Quidé, Yann; Lissek, Shmuel; Cisler, Josh; Grupe, Daniel W; Larson, Christine; Feola, Brandee; May, Geoffrey; Abdallah, Chadi G; Lanius, Ruth; Thompson, Paul M; Morey, Rajendra A; Ressler, Kerry J	January 1, 2026	Not Determined
40692500	Create Study	A whole-brain voxel-based analysis of structural abnormalities in PTSD: An ENIGMA-PGC study.	European psychiatry : the journal of the Association of European Psychiatrists	See, Cheryl R Z; Si, Shuqing; Baird, C Lexi; Haswell, Courtney C; Hussain, Ahmed; Olff, Miranda; Veltman, Dick J; Frijling, Jessie L; van Zuiden, Mirjam; Koch, Saskia B J; Nawijn, Laura; Wang, Li; Zhu, Ye; Li, Gen; Neria, Yuval; Zhu, Xi; Suarez-Jimenez, Benjamin; Zilcha-Mano, Sigal; Lazarov, Amit; Stevens, Jennifer S; Ressler, Kerry; Fani, Negar; Jovanovic, Tanja; van Rooij, Sanne J H; Kaufman, Milissa L; Lebois, Lauren A M; Rosso, Isabelle M; Olson, Elizabeth A; Baker, Justin T; Sponheim, Scott R; Disner, Seth G; Davenport, Nicholas D; Etkin, Amit; Maron-Katz, Adi; Stein, Murray B; Shenton, Martha E; Stein, Dan J; Ipser, Jonathan; Koopowitz, Sheri-Michelle; Seedat, Soraya; du Plessis, Stefan; van den Heuvel, Leigh L; Lissek, Shmuel; Berg, Hannah; Straube, Thomas; Hofman, David; Baugh, Lee A; Forster, Gina L; Simons, Raluca M; Simons, Jeffrey S; Magnotta, Vincent A; Fercho, Kelene A; Wang, Xin; Cotton, Andrew S; O'Leary, Erin N; Xie, Hong; Grupe, Daniel W; Nitschke, Jack B; Davidson, Richard J; Larson, Christine L; deRoon-Cassini, Terri A; Tomas, Carissa W; Fitzgerald, Jacklynn M; Blackford, Jennifer Urbano; Olatunji, Bunmi O; Gordon, Evan M; May, Geoffrey; Nelson, Steven M; Lanius, Ruth; Théberge, Jean; Densmore, Maria; Neufeld, Richard W J; Abdallah, Chadi G; Averill, Christopher L; Harpaz-Rotem, Ilan; Levy, Ifat; Krystal, John H; Geuze, Elbert; van Lutterveld, Remko; Dennis, Emily L; Tate, David F; Cifu, David X; Walker, William C; Wilde, Elisabeth A; van der Wee, Nic J A; Vermeiren, Robert R J M; van der Werff, Steven J A; McLaughlin, Katie; Sambrook, Kelly; Peverill, Matthew; Radua, Joaquim; Salminen, Lauren E; Jahanshad, Neda; Thomopoulos, Sophia I; James, Anthony; Valmaggia, Lucia; Thompson, Paul M; Morey, Rajendra A; Kempton, Matthew J	July 22, 2025	Not Determined
40667083	Create Study	Image-Based Meta- and Mega-Analysis (IBMMA): A Unified Framework for Large-Scale, Multi-Site, Neuroimaging Data Analysis.	bioRxiv : the preprint server for biology	Steele, Nick; Morey, Rajendra A; Hussain, Ahmed; Russell, Courtney; Suarez-Jimenez, Benjamin; Pozzi, Elena; Jameei, Hadis; Schmaal, Lianne; Veer, Ilya M; Waller, Lea; Jahanshad, Neda; Thomopoulos, Sophia I; Salminen, Lauren E; Olff, Miranda; Frijling, Jessie L; Veltman, Dick J; Koch, Saskia B J; Nawijn, Laura; van Zuiden, Mirjam; Wang, Li; Zhu, Ye; Li, Gen; Stein, Dan J; Ipser, Jonathan; Neria, Yuval; Zhu, Xi; Ravid, Orren; Zilcha-Mano, Sigal; Lazarov, Amit; Huggins, Ashley A; Stevens, Jennifer S; Ressler, Kerry; Jovanovic, Tanja; van Rooij, Sanne J H; Fani, Negar; Mueller, Sven C; Hudson, Anna R; Daniels, Judith K; Sierk, Anika; Manthey, Antje; Walter, Henrik; van der Wee, Nic J A; van der Werff, Steven J A; Vermeiren, Robert R J M; Schmahl, Christian; Herzog, Julia I; Rektor, Ivan; Říha, Pavel; Kaufman, Milissa L; Lebois, Lauren A M; Baker, Justin T; Rosso, Isabelle M; Olson, Elizabeth A; King, Anthony; Liberzon, Israel; Angstadt, Michael; Davenport, Nicholas D; Disner, Seth G; Sponheim, Scott R; Straube, Thomas; Hofmann, David; Lu, Guangming; Qi, Rongfeng; Wang, Xin; Kunch, Austin; Xie, Hong; Quidé, Yann; El-Hage, Wissam; Lissek, Shmuel; Berg, Hannah; Bruce, Steven E; Cisler, Josh; Ross, Marisa; Herringa, Ryan J; Grupe, Daniel W; Nitschke, Jack B; Davidson, Richard J; Larson, Christine; deRoon-Cassini, Terri A; Tomas, Carissa W; Fitzgerald, Jacklynn M; Elman, Jeremy; Panizzon, Matthew; Franz, Carol E; Lyons, Michael J; Kremen, William S; Feola, Brandee; Blackford, Jennifer U; Olatunji, Bunmi O; May, Geoffrey; Nelson, Steven M; Gordon, Evan M; Abdallah, Chadi G; Lanius, Ruth; Densmore, Maria; Théberge, Jean; Neufeld, Richard W J; Thompson, Paul M; Sun, Delin	June 17, 2025	Not Determined
40661416	Create Study	Childhood Maltreatment and Deviations from Normative Brain Structure: Results from 3,711 Individuals from the ENIGMA MDD and ENIGMA PTSD.	bioRxiv : the preprint server for biology	ENIGMA MDD Working Group; ENIGMA PTSD Working Group	June 8, 2025	Not Determined
40166540	Create Study	Structural covariance of early visual cortex is negatively associated with PTSD symptoms: A Mega-Analysis from the ENIGMA PTSD workgroup.	medRxiv : the preprint server for health sciences	Harnett, Nathaniel G; Joshi, Soumyaa; Kumar, Poornima; Russell, Courtney; Dillon, Daniel G; Baker, Justin T; Pizzagalli, Diego A; Kaufman, Milissa L; Nickerson, Lisa N; Jahanshad, Neda; Salminen, Lauren E; Thomopoulos, Sophia I; Frijling, Jessie L; Veltman, Dick J; Koch, Saskia B J; Nawijn, Laura; van Zuiden, Mirjam; Zhu, Ye; Li, Gen; Ipser, Jonathan; Zhu, Xi; Ravid, Orren; Zilcha-Mano, Sigal; Lazarov, Amit; Suarez-Jimenez, Benjamin; Sun, Delin; Hussain, Ahmed; Huggins, Ashley A; Jovanovic, Tanja; van Rooij, Sanne J H; Fani, Negar; Hudson, Anna R; Sierk, Anika; Manthey, Antje; Walter, Henrik; van der Wee, Nic J A; van der Werff, Steven J A; Vermeiren, Robert R J M; Říha, Pavel; Lebois, Lauren A M; Rosso, Isabelle M; Olson, Elizabeth A; Liberzon, Israel; Angstadt, Mike; Disner, Seth G; Sponheim, Scott R; Koopowitz, Sheri-Michelle; Hofmann, David; Qi, Rongfeng; Maron-Katz, Adi; Kunch, Austin; Xie, Hong; El-Hage, Wissam; Berg, Hannah; Bruce, Steven E; McLaughlin, Katie A; Peverill, Matthew; Sambrook, Kelly; Ross, Marisa; Herringa, Ryan J; Nitschke, Jack B; Davidson, Richard J; deRoon-Cassini, Terri A; Tomas, Carissa W; Fitzgerald, Jacklynn M; Blackford, Jennifer Urbano; Olatunji, Bunmi O; Nelson, Steven M; Gordon, Evan M; Densmore, Maria; Théberge, Jean; Neufeld, Richard W J; Olff, Miranda; Wang, Li; Stein, Dan J; Neria, Yuval; Stevens, Jennifer S; Mueller, Sven C; Daniels, Judith K; Rektor, Ivan; King, Anthony; Davenport, Nicholas D; Straube, Thomas; Lu, Guangming; Etkin, Amit; Wang, Xin; Quidé, Yann; Lissek, Shmuel; Cisler, Josh; Grupe, Daniel W; Larson, Christine; Feola, Brandee; May, Geoffrey; Abdallah, Chadi G; Lanius, Ruth; Thompson, Paul M; Morey, Rajendra A; Ressler, Kerry	March 19, 2025	Not Determined
39985923	Create Study	The diagnostic utility of the PCL-5 in a traumatically injured black population.	Journal of anxiety disorders	Geier, Timothy J; Vine, Kaylen; Torres, Lucas; Larson, Christine L; deRoon-Cassini, Terri A	April 1, 2025	Not Determined
39624980	Create Study	Pandemic-Related Stress Increases PTSD and Depression Risk in Traumatic Injury Patients: A Comparative Study of Pre- and Peri-Pandemic Trauma Cases.	Stress and health : journal of the International Society for the Investigation of Stress	Zapata, Juan Pablo; Tomas, Carissa W; Timmer-Murillo, Sydney; deRoon Cassini, Terri A; Larson, Christine; Torres, Lucas; Brandolino, Amber; Geier, Timothy; Khan, Hason; Schramm, Andrew T	April 1, 2025	Not Determined
39169008	Create Study	Investigating the bed nucleus of the stria terminalis as a predictor of posttraumatic stress disorder in Black Americans and the moderating effects of racial discrimination.	Translational psychiatry	Petranu, Kevin; Webb, E Kate; Tomas, Carissa W; Harb, Farah; Torres, Lucas; deRoon-Cassini, Terri A; Larson, Christine L	August 21, 2024	Not Determined
38799039	Create Study	Trajectories of Anhedonia Symptoms after Traumatic Injury.	European journal of trauma & dissociation = Revue europeenne du trauma et de la dissociation	Pina, Isela G; Timmer-Murillo, Sydney C; Larson, Christine L; deRoon-Cassini, Terri A; Tomas, Carissa W	June 1, 2024	Not Determined
38711866	Create Study	Childhood Maltreatment and Amygdala-Mediated Anxiety and Posttraumatic Stress Following Adult Trauma.	Biological psychiatry global open science	Harb, Farah; Liuzzi, Michael T; Huggins, Ashley A; Webb, E Kate; Fitzgerald, Jacklynn M; Krukowski, Jessica L; deRoon-Cassini, Terri A; Larson, Christine L	July 1, 2024	Not Determined
38695787	Create Study	Subtypes of childhood maltreatment and posttraumatic stress disorder symptoms in an adult trauma sample: The mechanistic role of sleep.	Psychological trauma : theory, research, practice and policy	Harb, Farah; González-Van Wart, Alexandra; Brzezinski, John; deRoon-Cassini, Terri A; Larson, Christine L	February 1, 2025	Not Determined
38650107	Create Study	Racial discrimination increases the risk for nonremitting posttraumatic stress disorder symptoms in traumatically injured Black individuals living in the United States.	Journal of traumatic stress	Torres, Lucas; Geier, Timothy J; Tomas, Carissa W; Bird, Claire M; Timmer-Murillo, Sydney; Larson, Christine L; deRoon-Cassini, Terri A	August 1, 2024	Not Determined
38298781	Create Study	Intrusive Traumatic Re-Experiencing Domain: Functional Connectivity Feature Classification by the ENIGMA PTSD Consortium.	Biological psychiatry global open science	Suarez-Jimenez, Benjamin; Lazarov, Amit; Zhu, Xi; Zilcha-Mano, Sigal; Kim, Yoojean; Marino, Claire E; Rjabtsenkov, Pavel; Bavdekar, Shreya Y; Pine, Daniel S; Bar-Haim, Yair; Larson, Christine L; Huggins, Ashley A; Terri deRoon-Cassini; Tomas, Carissa; Fitzgerald, Jacklynn; Kennis, Mitzy; Varkevisser, Tim; Geuze, Elbert; Quidé, Yann; El Hage, Wissam; Wang, Xin; O'Leary, Erin N; Cotton, Andrew S; Xie, Hong; Shih, Chiahao; Disner, Seth G; Davenport, Nicholas D; Sponheim, Scott R; Koch, Saskia B J; Frijling, Jessie L; Nawijn, Laura; van Zuiden, Mirjam; Olff, Miranda; Veltman, Dick J; Gordon, Evan M; May, Geoffery; Nelson, Steven M; Jia-Richards, Meilin; Neria, Yuval; Morey, Rajendra A	January 1, 2024	Not Determined
38195980	Create Study	Smaller total and subregional cerebellar volumes in posttraumatic stress disorder: a mega-analysis by the ENIGMA-PGC PTSD workgroup.	Molecular psychiatry	Huggins, Ashley A; Baird, C Lexi; Briggs, Melvin; Laskowitz, Sarah; Hussain, Ahmed; Fouda, Samar; Haswell, Courtney; Sun, Delin; Salminen, Lauren E; Jahanshad, Neda; Thomopoulos, Sophia I; Veltman, Dick J; Frijling, Jessie L; Olff, Miranda; van Zuiden, Mirjam; Koch, Saskia B J; Nawjin, Laura; Wang, Li; Zhu, Ye; Li, Gen; Stein, Dan J; Ipser, Jonathan; Seedat, Soraya; du Plessis, Stefan; van den Heuvel, Leigh L; Suarez-Jimenez, Benjamin; Zhu, Xi; Kim, Yoojean; He, Xiaofu; Zilcha-Mano, Sigal; Lazarov, Amit; Neria, Yuval; Stevens, Jennifer S; Ressler, Kerry J; Jovanovic, Tanja; van Rooij, Sanne J H; Fani, Negar; Hudson, Anna R; Mueller, Sven C; Sierk, Anika; Manthey, Antje; Walter, Henrik; Daniels, Judith K; Schmahl, Christian; Herzog, Julia I; Říha, Pavel; Rektor, Ivan; Lebois, Lauren A M; Kaufman, Milissa L; Olson, Elizabeth A; Baker, Justin T; Rosso, Isabelle M; King, Anthony P; Liberzon, Isreal; Angstadt, Mike; Davenport, Nicholas D; Sponheim, Scott R; Disner, Seth G; Straube, Thomas; Hofmann, David; Qi, Rongfeng; Lu, Guang Ming; Baugh, Lee A; Forster, Gina L; Simons, Raluca M; Simons, Jeffrey S; Magnotta, Vincent A; Fercho, Kelene A; Maron-Katz, Adi; Etkin, Amit; Cotton, Andrew S; O'Leary, Erin N; Xie, Hong; Wang, Xin; Quidé, Yann; El-Hage, Wissam; Lissek, Shmuel; Berg, Hannah; Bruce, Steven; Cisler, Josh; Ross, Marisa; Herringa, Ryan J; Grupe, Daniel W; Nitschke, Jack B; Davidson, Richard J; Larson, Christine L; deRoon-Cassini, Terri A; Tomas, Carissa W; Fitzgerald, Jacklynn M; Blackford, Jennifer Urbano; Olatunji, Bunmi O; Kremen, William S; Lyons, Michael J; Franz, Carol E; Gordon, Evan M; May, Geoffrey; Nelson, Steven M; Abdallah, Chadi G; Levy, Ifat; Harpaz-Rotem, Ilan; Krystal, John H; Dennis, Emily L; Tate, David F; Cifu, David X; Walker, William C; Wilde, Elizabeth A; Harding, Ian H; Kerestes, Rebecca; Thompson, Paul M; Morey, Rajendra	March 1, 2024	Not Determined
38070623	Create Study	Experiences of racial discrimination and adverse gene expression among black individuals in a level 1 trauma center sample.	Brain, behavior, and immunity	Bird, Claire M; Kate Webb, E; Cole, Steven W; Tomas, Carissa W; Knight, Jennifer M; Timmer-Murillo, Sydney C; Larson, Christine L; deRoon-Cassini, Terri A; Torres, Lucas	February 1, 2024	Not Determined
38017161	Create Study	Examining the association between posttraumatic stress disorder and disruptions in cortical networks identified using data-driven methods.	Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology	Yang, Jin; Huggins, Ashley A; Sun, Delin; Baird, C Lexi; Haswell, Courtney C; Frijling, Jessie L; Olff, Miranda; van Zuiden, Mirjam; Koch, Saskia B J; Nawijn, Laura; Veltman, Dick J; Suarez-Jimenez, Benjamin; Zhu, Xi; Neria, Yuval; Hudson, Anna R; Mueller, Sven C; Baker, Justin T; Lebois, Lauren A M; Kaufman, Milissa L; Qi, Rongfeng; Lu, Guang Ming; Říha, Pavel; Rektor, Ivan; Dennis, Emily L; Ching, Christopher R K; Thomopoulos, Sophia I; Salminen, Lauren E; Jahanshad, Neda; Thompson, Paul M; Stein, Dan J; Koopowitz, Sheri M; Ipser, Jonathan C; Seedat, Soraya; du Plessis, Stefan; van den Heuvel, Leigh L; Wang, Li; Zhu, Ye; Li, Gen; Sierk, Anika; Manthey, Antje; Walter, Henrik; Daniels, Judith K; Schmahl, Christian; Herzog, Julia I; Liberzon, Israel; King, Anthony; Angstadt, Mike; Davenport, Nicholas D; Sponheim, Scott R; Disner, Seth G; Straube, Thomas; Hofmann, David; Grupe, Daniel W; Nitschke, Jack B; Davidson, Richard J; Larson, Christine L; deRoon-Cassini, Terri A; Blackford, Jennifer U; Olatunji, Bunmi O; Gordon, Evan M; May, Geoffrey; Nelson, Steven M; Abdallah, Chadi G; Levy, Ifat; Harpaz-Rotem, Ilan; Krystal, John H; Morey, Rajendra A; Sotiras, Aristeidis	February 1, 2024	Not Determined
37871776	Create Study	The Dichotomy of Threat and Deprivation as Subtypes of Childhood Maltreatment: Differential Functional Connectivity Patterns of Threat and Reward Circuits in an Adult Trauma Sample.	Biological psychiatry. Cognitive neuroscience and neuroimaging	Liuzzi, Michael T; Harb, Farah; Petranu, Kevin; Huggins, Ashley A; Webb, E Kate; Fitzgerald, Jacklynn M; Krukowski, Jessica L; Miskovich, Tara A; deRoon-Cassini, Terri A; Larson, Christine L	February 1, 2024	Not Determined
37339014	Create Study	Attributional negativity bias and acute stress disorder symptoms mediate the association between trauma history and future posttraumatic stress disorder.	Journal of traumatic stress	Webb, E Kate; Timmer-Murillo, Sydney C; Huggins, Ashley A; Tomas, Carissa W; deRoon-Cassini, Terri A; Larson, Christine L	August 1, 2023	Not Determined
37249827	Create Study	History of Racial Discrimination by Police Contributes to Worse Physical and Emotional Quality of Life in Black Americans After Traumatic Injury.	Journal of racial and ethnic health disparities	Geier, Timothy J; Timmer-Murillo, Sydney C; Brandolino, Amber M; Piña, Isela; Harb, Farah; deRoon-Cassini, Terri A	June 1, 2024	Not Determined
36104984	Create Study	Event centrality and posttraumatic stress symptoms after traumatic injury: A longitudinal investigation.	Journal of traumatic stress	Stevens, Sarah K; Timmer-Murillo, Sydney C; Tomas, Carissa W; Boals, Adriel; Larson, Christine L; deRoon-Cassini, Terri; Larsen, Sadie E	December 1, 2022	Not Determined

helpcenter.collection.publications-tab

Collection - Publications

The number of Publications is displayed in parentheses next to the tab name. Clicking on any of the Publication Titles will open the Publication in a new internet browsing tab.

Collection Owners, Program Officers, and users with Submission or Administrative Privileges for the Collection may mark a publication as either Relevant or Not Relevant in the Status column.

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How can I determine if a publication is relevant?

Publications are considered relevant to a collection when the data shared is directly related to the project or collection.
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Indicates that the publication has not yet been reviewed and/or marked as Relevant or Not Relevant so it has not been determined whether an NDA Study is expected.
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A publication that is not based on data related to the aims of the grant/project associated with the Collection or not based on any data such as a review article and, therefore, an NDA Study is not expected to be created.
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PubMed ID

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Relevant Publication

A publication that is based on data related to the aims of the grant/project associated with the Collection and, therefore, an NDA Study is expected to be created.

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Data Expected List: Mandatory Data Structures

These data structures are mandatory for your NDA Collection. Please update the Targeted Enrollment number to accurately represent the number of subjects you expect to submit for the entire study.

For NIMH HIV-related research that involves human research participants: Select the dictionary or dictionaries most appropriate for your research. If your research does not require all three data dictionaries, just ignore the ones you do not need. There is no need to delete extra data dictionaries from your NDA Collection. You can adjust the Targeted Enrollment column in the Data Expected tab to “0” for those unnecessary data dictionaries. At least one of the three data dictionaries must have a non-zero value.

Data Expected	Targeted Enrollment	Initial Submission	Subjects Submitted	Initial Share	Subjects Shared	Status
Research Subject and Pedigree	220	07/15/2017	228	11/15/2017	228	Approved

To create your project's Data Expected list, use the "+New Data Expected" to add or request existing structures and to request new Data Structures that are not in the NDA Data Dictionary.

If the Structure you need already exists, locate it and specify your dates and enrollment when adding it to your Data Expected list. If you require changes to the Structure you need, select the indicator stating "No, it requires changes to meet research needs," and upload a file containing your requested changes.

If the structure you need is not yet defined in the Data Dictionary, you can select "Upload Definition" and attach the necessary materials to request its creation.

When selecting the expected dates for your data, make sure to follow the standard Data Sharing Regimen and choose dates within the date ranges that correspond to your project start and end dates.

Please visit the Completing Your Data Expected Tutorial for more information.

Data Expected List: Data Structures per Research Aims

These data structures are specific to your research aims and should list all data structures in which data will be collected and submitted for this NDA Collection. Please update the Targeted Enrollment number to accurately represent the number of subjects you expect to submit for the entire study.

Data Expected	Targeted Enrollment	Initial Submission	Subjects Submitted	Initial Share	Subjects Shared	Status
State-Trait Anger Expression Inventory	220	01/15/2017	221	02/28/2017	221	Approved
Life Events Checklist	220	01/15/2017	221	05/15/2017	221	Approved
Childhood Trauma Questionnaire	220	01/15/2017	214	02/28/2017	214	Approved
Demographics	220	01/15/2017	220	05/15/2017	220	Approved
Vital Signs Assessment	220	01/15/2017	229	05/15/2017	229	Approved
SF36 Health QoL	220	07/15/2017	201	11/15/2017	201	Approved
Multigroup Ethnic Identity Measure	220	01/15/2017	215	02/28/2017	215	Approved
Substance Use Survey	220	01/15/2017	221	02/28/2017	221	Approved
Depression, Anxiety, and Stress Scale	220	01/15/2017	221	02/28/2017	221	Approved
Intolerance of Uncertainty Scale	220	01/15/2017	215	02/28/2017	215	Approved
State-Trait Anxiety Inventory for Adults	220	01/15/2017	215	02/28/2017	215	Approved
MOS-Social Support	220	01/15/2017	215	02/28/2017	215	Approved
Mini-International Neuropsychiatric Interview (MINI)	195	07/15/2017	195	11/15/2017	195	Approved
PTSD Checklist - Civilian	220	01/15/2017	219	02/28/2017	219	Approved
Sheehan Disability Scale	220	01/15/2017	221	02/28/2017	221	Approved
Drug Screen	220	01/15/2017	224	02/28/2017	224	Approved
Imaging (Structural, fMRI, DTI, PET, microscopy)	220	01/15/2017	167	05/15/2017	167	Approved
Peritraumatic Distress Inventory	220	01/15/2017	229	02/28/2017	229	Approved
Snaith-Hamilton Pleasure Scale	220	01/15/2017	218	02/28/2017	218	Approved
PTSD Scale for DSM-5	192	07/15/2017	192	11/15/2017	192	Approved
Traumatic Brain Injury	220	01/15/2017	229	02/28/2017	229	Approved
Predicting PTSD Form	220	01/15/2017	229	02/28/2017	229	Approved
Trauma Quality of Life Measure	220	01/15/2017	200	02/28/2017	200	Approved
Emotion Dysregulation Scale	220	01/15/2017	221	02/28/2017	221	Approved
Trauma Neutral Script	167	01/15/2017	166	02/28/2017	166	Approved
Perceived Injury Severity	220	01/15/2017	229	02/28/2017	229	Approved
Drug Abuse Screening Test	220	01/15/2017	221	02/28/2017	221	Approved
Injustices Experiences Questionnaire	220	01/15/2017	215	02/28/2017	215	Approved
Insomnia Severity Index	220	01/15/2017	221	02/28/2017	221	Approved
Subtypes of Antisocial Behavior	190	01/15/2017	190	02/28/2017	190	Approved
Perceived Ethnic Discrimination Questionnaire	220	01/15/2017	221	02/28/2017	221	Approved
Centrality of Event	190	01/15/2017	190	05/15/2017	190	Approved
Mini IPIP	220	01/15/2017	212	02/28/2017	212	Approved
Just World Belief	220	01/15/2017	215	02/28/2017	215	Approved
WebNeuro	220	01/15/2017	216	02/28/2017	216	Approved
Crisis in Family Systems	170	07/15/2017	170	11/15/2017	170	Approved

Structure not yet defined

No Status history for this Data Expected has been recorded yet

helpcenter.collection.data-expected-tab

Collection - Data Expected

The Data Expected tab displays the list of all data that NDA expects to receive in association with the Collection as defined by the contributing researcher, as well as the dates for the expected initial upload of the data, and when it is first expected to be shared, or with the research community. Above the primary table of Data Expected, any publications determined to be relevant to the data within the Collection are also displayed - members of the contributing research group can use these to define NDA Studies, connecting those papers to underlying data in NDA.

The tab is used both as a reference for those accessing shared data, providing information on what is expected and when it will be shared, and as the primary tracking mechanism for contributing projects. It is used by both contributing primary researchers, secondary researchers, and NIH Program and Grants Management staff.

Researchers who are starting their project need to update their Data Expected list to include all the Data Structures they are collecting under their grant and set their initial submission and sharing schedule according to the NDA Data Sharing Regimen.

To add existing Data Structures from the Data Dictionary, to request new Data Structure that are not in the Dictionary, or to request changes to existing Data Structures, click "+New Data Expected".

For step-by-step instructions on how to add existing Data Structures, request changes to an existing Structure, or request a new Data Structure, please visit the Completing Your Data Expected Tutorial.

If you are a contributing researcher creating this list for the first time, or making changes to the list as your project progress, please note the following:

Although items you add to the list and changes you make are displayed, they are not committed to the system until you Save the entire page using the "Save" button at the bottom of your screen. Please Save after every change to ensure none of your work is lost.
If you attempt to add a new structure, the title you provide must be unique - if another structure exists with the same name your change will fail.
Adding a new structure to this list is the only way to request the creation of a new Data Dictionary definition.

Frequently Asked Questions

What is an NDA Data Structure?

An NDA Data Structure is comprised of multiple Data Elements to make up an electronic definition of an assessment, measure, questionnaire, etc will have a corresponding Data Structure.
What is the NDA Data Dictionary?

The NDA Data Dictionary is comprised of electronic definitions known as Data Structures.

Glossary

Analyzed Data

Data specific to the primary aims of the research being conducted (e.g. outcome measures, other dependent variables, observations, laboratory results, analyzed images, volumetric data, etc.) including processed images.
Data Item

Items listed on the Data Expected list in the Collection which may be an individual and discrete Data Structure, Data Structure Category, or Data Structure Group.
Data Structure

A defined organization and group of Data Elements to represent an electronic definition of a measure, assessment, questionnaire, or collection of data points. Data structures that have been defined in the NDA Data Dictionary are available at https://nda.nih.gov/general-query.html?q=query=data-structure
Data Structure Category

An NDA term describing the affiliation of a Data Structure to a Category, which may be disease/disorder or diagnosis related (Depression, ADHD, Psychosis), specific to data type (MRI, eye tracking, omics), or type of data (physical exam, IQ).
Data Structure Group

A Data Item listed on the Data Expected tab of a Collection that indicates a group of Data Structures (e.g., ADOS or SCID) for which data may be submitted instead of a specific Data Structure identified by version, module, edition, etc. For example, the ADOS Data Structure Category includes every ADOS Data Structure such as ADOS Module 1, ADOS Module 2, ADOS Module 1 - 2nd Edition, etc. The SCID Data Structure Group includes every SCID Data Structure such as SCID Mania, SCID V Mania, SCID PTSD, SCID-V Diagnosis, and more.
Evaluated Data

A new Data Structure category, Evaluated Data is analyzed data resulting from the use of computational pipelines in the Cloud and can be uploaded directly back to a miNDAR database. Evaluated Data is expected to be listed as a Data Item in the Collection's Data Expected Tab.
Imaging Data

Imaging+ is an NDA term which encompasses all imaging related data including, but not limited to, images (DTI, MRI, PET, Structural, Spectroscopy, etc.) as well as neurosignal data (EEG, fMRI, MEG, EGG, eye tracking, etc.) and Evaluated Data.
Initial Share Date

Initial Submission and Initial Share dates should be populated according to the NDA Data Sharing Terms and Conditions. Any modifications to these will go through the approval processes outlined above. Data will be shared with authorized users upon publication (via an NDA Study) or 1-2 years after the grant end date specified on the first Notice of Award, as defined in the applicable Data Sharing Terms and Conditions.
Initial Submission Date

Initial Submission and Initial Share dates should be populated according to these NDA Data Sharing Terms and Conditions. Any modifications to these will go through the approval processes outlined above. Data for all subjects is not expected on the Initial Submission Date and modifications may be made as necessary based on the project's conduct.
Research Subject and Pedigree

An NDA created Data Structure used to convey basic information about the subject such as demographics, pedigree (links family GUIDs), diagnosis/phenotype, and sample location that are critical to allow for easier querying of shared data.
Submission Cycle

The NDA has two Submission Cycles per year - January 15 and July 15.
Submission Exemption

An interface to notify NDA that data may not be submitted during the upcoming/current submission cycle.

Contact NDA Help Desk

Collection Owners and those with Collection Administrator permission, may edit a collection. The following is currently available for Edit on this page:

Associated Studies

Studies that have been defined using data from a Collection are important criteria to determine the value of data shared. The number of subjects column displays the counts from this Collection that are included in a Study, out of the total number of subjects in that study. The Data Use column represents whether or not the study is a primary analysis of the data or a secondary analysis. State indicates whether the study is private or shared with the research community.

Study NameFilter by Study Name	DOIFilter by DOI	AbstractFilter by Abstract	Collection/Study SubjectsFilter by Collection/Study Subjects	Data UsageFilter by Data Usage	StateFilter by State
No records found.

helpcenter.collection.associated-studies-tab

Collection - Associated Studies

Clicking on the Study Title will open the study details in a new internet browser tab. The Abstract is available for viewing, providing the background explanation of the study, as provided by the Collection Owner.

Primary v. Secondary Analysis: The Data Usage column will have one of these two choices. An associated study that is listed as being used for Primary Analysis indicates at least some and potentially all of the data used was originally collected by the creator of the NDA Study. Secondary Analysis indicates the Study owner was not involved in the collection of data, and may be used as supporting data.

Private v. Shared State: Studies that remain private indicate the associated study is only available to users who are able to access the collection. A shared study is accessible to the general public.

Frequently Asked Questions

How do I associate a study to my collection?

Studies are associated to the Collection automatically when the data is defined in the Study.

Glossary

Associated Studies Tab

A tab in a Collection that lists the NDA Studies that have been created using data from that Collection including both Primary and Secondary Analysis NDA Studies.

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