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1 Numbers reported are subjects by age
New Trial
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Format should be in the following format: Activity Code, Institute Abbreviation, and Serial Number. Grant Type, Support Year, and Suffix should be excluded. For example, grant 1R01MH123456-01A1 should be entered R01MH123456

Please select an experiment type below

Collection - Use Existing Experiment
To associate an experiment to the current collection, just select an axperiment from the table below then click the associate experiment button to persist your changes (saving the collection is not required). Note that once an experiment has been associated to two or more collections, the experiment will not longer be editable.

The table search feature is case insensitive and targets the experiment id, experiment name and experiment type columns. The experiment id is searched only when the search term entered is a number, and filtered using a startsWith comparison. When the search term is not numeric the experiment name is used to filter the results.
SelectExperiment IdExperiment NameExperiment Type
Created On
24HI-NGS_R1Omics02/16/2011
475MB1-10 (CHOP)Omics06/07/2016
490Discovery and CRISPR validation of genetic factors associated with antipsychotic-induced weight gain and cardiometabolic riskOmics07/07/2016
501PharmacoBOLD Resting StatefMRI07/27/2016
506PVPREFOmics08/05/2016
509ABC-CT Resting v2EEG08/18/2016
13Comparison of FI expression in Autistic and Neurotypical Homo SapiensOmics12/28/2010
18AGRE/Broad Affymetrix 5.0 Genotype ExperimentOmics01/06/2011
22Stitching PCR SequencingOmics02/14/2011
26ASD_MethylationOmics03/01/2011
29Microarray family 03 (father, mother, sibling)Omics03/24/2011
37Standard paired-end sequencing of BCRsOmics04/19/2011
38Illumina Mate-Pair BCR sequencingOmics04/19/2011
39Custom Jumping LibrariesOmics04/19/2011
40Custom CapBPOmics04/19/2011
41ImmunofluorescenceOmics05/11/2011
43Autism brain sample genotyping, IlluminaOmics05/16/2011
47ARRA Autism Sequencing Collaboration at Baylor. SOLiD 4 SystemOmics08/01/2011
53AGRE Omni1-quadOmics10/11/2011
59AGP genotypingOmics04/03/2012
60Ultradeep 454 sequencing of synaptic genes from postmortem cerebella of individuals with ASD and neurotypical controlsOmics06/23/2012
63Microemulsion PCR and Targeted Resequencing for Variant Detection in ASDOmics07/20/2012
76Whole Genome Sequencing in Autism FamiliesOmics01/03/2013
519RestingfMRI11/08/2016
90Genotyped IAN SamplesOmics07/09/2013
91NJLAGS Axiom Genotyping ArrayOmics07/16/2013
93AGP genotyping (CNV)Omics09/06/2013
106Longitudinal Sleep Study. H20 200. Channel set 2EEG11/07/2013
107Longitudinal Sleep Study. H20 200. Channel set 3EEG11/07/2013
108Longitudinal Sleep Study. AURA 200EEG11/07/2013
105Longitudinal Sleep Study. H20 200. Channel set 1EEG11/07/2013
109Longitudinal Sleep Study. AURA 400EEG11/07/2013
116Gene Expression Analysis WG-6Omics01/07/2014
131Jeste Lab UCLA ACEii: Charlie Brown and Sesame Street - Project 1Eye Tracking02/27/2014
132Jeste Lab UCLA ACEii: Animacy - Project 1Eye Tracking02/27/2014
133Jeste Lab UCLA ACEii: Mom Stranger - Project 2Eye Tracking02/27/2014
134Jeste Lab UCLA ACEii: Face Emotion - Project 3Eye Tracking02/27/2014
145AGRE/FMR1_Illumina.JHUOmics04/14/2014
146AGRE/MECP2_Sanger.JHUOmics04/14/2014
147AGRE/MECP2_Junior.JHUOmics04/14/2014
151Candidate Gene Identification in familial AutismOmics06/09/2014
152NJLAGS Whole Genome SequencingOmics07/01/2014
154Math Autism Study - Vinod MenonfMRI07/15/2014
155RestingfMRI07/25/2014
156SpeechfMRI07/25/2014
159EmotionfMRI07/25/2014
160syllable contrastEEG07/29/2014
167School-age naturalistic stimuliEye Tracking09/19/2014
44AGRE/Broad Affymetrix 5.0 Genotype ExperimentOmics06/27/2011
45Exome Sequencing of 20 Sporadic Cases of Autism Spectrum DisorderOmics07/15/2011
Collection - Add Experiment
Add Supporting Documentation
Select File

To add an existing Data Structure, enter its title in the search bar. If you need to request changes, select the indicator "No, it requires changes to meet research needs" after selecting the Structure, and upload the file with the request changes specific to the selected Data Structure. Your file should follow the Request Changes Procedure. If the Data Structure does not exist, select "Request New Data Structure" and upload the appropriate zip file.

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Your Collection is now in Data Analysis phase and exempt from biannual submissions. Analyzed data is still expected prior to publication or no later than the project end date.

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Collection Summary Collection Charts
Collection Title Collection Investigators Collection Description
Deprivation and Threat: Dimensions of Early Experience and Neural Development
Katie Mclaughlin 
Extensive research finds robust links between mental health and childhood adversity CA , encompassing diverse exposures from child abuse to poverty. Despite the strength and consistency of these findings, the mechanisms producing such links remain poorly specified. In particular, past research has failed to identify how specific environmental experiences influence specific neural processes. Such limitations arise from the difficulty of precisely quantifying relevant CA and neural variables in children. The current proposal addresses these limitations by capitalizing on a unique, well characterized NIH-funded longitudinal cohort of children where multiple aspects of CA have been precisely assessed and use of rigorous neuroimaging methods to quantify functioning in specific neural circuits. We will use these methods to test a novel conceptual framework delineating how specific types of environmental experience influence specific neural processes, addressing Objective 1 of the NIMH Strategic Plan. Our model argues that different types of CA have distinct effects on neural development. The central distinction we make is between trauma and deprivation. Trauma exposure involves harm or threat of harm, resulting in fear learning mediated by limbic pathways that are well characterized in animals and conserved across species. We argue that child trauma alters development of circuits in the Negative Valence System that support emotional learning encompassing amygdala and ventromedial prefrontal cortex PFC . In contrast, deprivation involves absence of expected cognitive and social inputs and environmental complexity. Animal research shows that deprivation disrupts development in PFC and parietal cortex by hijacking the typical process of synaptic pruning. Thus we predict that social-cognitive deprivation influences Cognitive Control Systems, resulting in age-specific reductions in thickness and volume of dorsolateral PFC and superior parietal cortex and reduced performance on cognitive control tasks supported by these areas. Clearly, trauma and deprivation are correlated. Our unique design will measure these experiences on separate dimensions informed by rich preliminary data indicating distinct effects of trauma and deprivation on neural development even in samples with high exposure co-occurrence. Our proposed conceptual model will be tested by acquiring structural and functional MRI data on an existing sample of 300 children 1 3 in poverty, 1 3 near poverty, and 1 3 middle class followed since early childhood with significant variability in CA exposure. Psychopathology has been measured in previous waves of the study and will be collected multiple times during the study period. Study findings will provide critical information about how specific dimensions of environmental experience influence specific neural processes. Elucidating these mechanisms will not only build knowledge of how adverse environments alter neural development in ways that increase risk for psychopathology, but will also suggest possible targets for preventive interventions aimed at reducing psychopathology risk in children exposed to trauma and deprivation.
NIMH Data Archive
08/04/2016
Funding Completed
Close Out
No
$3,083,895.00
227
10.15154/4h33-f671
Loading Chart...
NIH - Extramural None



R01MH106482-01 Deprivation and Threat: Dimensions of Early Experience and Neural Development 12/10/2015 11/30/2020 11/30/2022 225 226 HARVARD UNIVERSITY $3,083,895.00

helpcenter.collection.general-tab

NDA Help Center

Collection - General Tab

Fields available for edit on the top portion of the page include:

  • Collection Title
  • Investigators
  • Collection Description
  • Collection Phase
  • Funding Source
  • Clinical Trials

Collection Phase: The current status of a research project submitting data to an NDA Collection, based on the timing of the award and/or the data that have been submitted.

  • Pre-Enrollment: The default entry made when the NDA Collection is created.
  • Enrolling: Data have been submitted to the NDA Collection or the NDA Data Expected initial submission date has been reached for at least one data structure category in the NDA Collection.
  • Data Analysis: Subject level data collection for the research project is completed and has been submitted to the NDA Collection. The NDA Collection owner or the NDA Help Desk may set this phase when they’ve confirmed data submission is complete and submitted subject counts match at least 90% of the target enrollment numbers in the NDA Data Expected. Data submission reminders will be turned off for the NDA Collection.
  • Funding Completed: The NIH grant award (or awards) associated with the NDA Collection has reached its end date. NDA Collections in Funding Completed phase are assigned a subphase to indicate the status of data submission.
    • The Data Expected Subphase indicates that NDA expects more data will be submitted
    • The Closeout Subphase indicates the data submission is complete.
    • The Sharing Not Met Subphase indicates that data submission was not completed as expected.

Blinded Clinical Trial Status:

  • This status is set by a Collection Owner and indicates the research project is a double blinded clinical trial. When selected, the public view of Data Expected will show the Data Expected items and the Submission Dates, but the targeted enrollment and subjects submitted counts will not be displayed.
  • Targeted enrollment and subjects submitted counts are visible only to NDA Administrators and to the NDA Collection or as the NDA Collection Owner.
  • When an NDA Collection that is flagged Blinded Clinical Trial reaches the maximum data sharing date for that Data Repository (see https://nda.nih.gov/nda/sharing-regimen.html), the embargo on Data Expected information is released.

Funding Source

The organization(s) responsible for providing the funding is listed here.

Supporting Documentation

Users with Submission privileges, as well as Collection Owners, Program Officers, and those with Administrator privileges, may upload and attach supporting documentation. By default, supporting documentation is shared to the general public, however, the option is also available to limit this information to qualified researchers only.

Grant Information

Identifiable details are displayed about the Project of which the Collection was derived from. You may click in the Project Number to view a full report of the Project captured by the NIH.

Clinical Trials

Any data that is collected to support or further the research of clinical studies will be available here. Collection Owners and those with Administrator privileges may add new clinical trials.

Frequently Asked Questions

  • How does the NIMH Data Archive (NDA) determine which Permission Group data are submitted into?
    During Collection creation, NDA staff determine the appropriate Permission Group based on the type of data to be submitted, the type of access that will be available to data access users, and the information provided by the Program Officer during grant award.
  • How do I know when a NDA Collection has been created?
    When a Collection is created by NDA staff, an email notification will automatically be sent to the PI(s) of the grant(s) associated with the Collection to notify them.
  • Is a single grant number ever associated with more than one Collection?
    The NDA system does not allow for a single grant to be associated with more than one Collection; therefore, a single grant will not be listed in the Grant Information section of a Collection for more than one Collection.
  • Why is there sometimes more than one grant included in a Collection?
    In general, each Collection is associated with only one grant; however, multiple grants may be associated if the grant has multiple competing segments for the same grant number or if multiple different grants are all working on the same project and it makes sense to hold the data in one Collection (e.g., Cooperative Agreements).

Glossary

  • Administrator Privilege
    A privilege provided to a user associated with an NDA Collection or NDA Study whereby that user can perform a full range of actions including providing privileges to other users.
  • Collection Owner
    Generally, the Collection Owner is the contact PI listed on a grant. Only one NDA user is listed as the Collection owner. Most automated emails are primarily sent to the Collection Owner.
  • Collection Phase
    The Collection Phase provides information on data submission as opposed to grant/project completion so while the Collection phase and grant/project phase may be closely related they are often different. Collection users with Administrative Privileges are encouraged to edit the Collection Phase. The Program Officer as listed in eRA (for NIH funded grants) may also edit this field. Changes must be saved by clicking the Save button at the bottom of the page. This field is sortable alphabetically in ascending or descending order. Collection Phase options include:
    • Pre-Enrollment: A grant/project has started, but has not yet enrolled subjects.
    • Enrolling: A grant/project has begun enrolling subjects. Data submission is likely ongoing at this point.
    • Data Analysis: A grant/project has completed enrolling subjects and has completed all data submissions.
    • Funding Completed: A grant/project has reached the project end date.
  • Collection Title
    An editable field with the title of the Collection, which is often the title of the grant associated with the Collection.
  • Grant
    Provides the grant number(s) for the grant(s) associated with the Collection. The field is a hyperlink so clicking on the Grant number will direct the user to the grant information in the NIH Research Portfolio Online Reporting Tools (RePORT) page.
  • Supporting Documentation
    Various documents and materials to enable efficient use of the data by investigators unfamiliar with the project and may include the research protocol, questionnaires, and study manuals.
  • NIH Research Initiative
    NDA Collections may be organized by scientific similarity into NIH Research Initiatives, to facilitate query tool user experience. NIH Research Initiatives map to one or multiple Funding Opportunity Announcements.
  • Permission Group
    Access to shared record-level data in NDA is provisioned at the level of a Permission Group. NDA Permission Groups consist of one or multiple NDA Collections that contain data with the same subject consents.
  • Planned Enrollment
    Number of human subject participants to be enrolled in an NIH-funded clinical research study. The data is provided in competing applications and annual progress reports.
  • Actual Enrollment
    Number of human subjects enrolled in an NIH-funded clinical research study. The data is provided in annual progress reports.
  • NDA Collection
    A virtual container and organization structure for data and associated documentation from one grant or one large project/consortium. It contains tools for tracking data submission and allows investigators to define a wide array of other elements that provide context for the data, including all general information regarding the data and source project, experimental parameters used to collect any event-based data contained in the Collection, methods, and other supporting documentation. They also allow investigators to link underlying data to an NDA Study, defining populations and subpopulations specific to research aims.
  • Data Use Limitations
    Data Use Limitations (DULs) describe the appropriate secondary use of a dataset and are based on the original informed consent of a research participant. NDA only accepts consent-based data use limitations defined by the NIH Office of Science Policy.
  • Total Subjects Shared
    The total number of unique subjects for whom data have been shared and are available for users with permission to access data.
IDNameCreated DateStatusType
547Emotional Face Processing12/14/2016ApprovedfMRI
548Spatial Working Memory12/14/2016ApprovedfMRI
551Fear Conditioning12/15/2016ApprovedfMRI
552Emotional Working Memory12/15/2016ApprovedfMRI
578Go No Go01/07/2017ApprovedfMRI
579Resting State01/07/2017ApprovedfMRI
580Structural Scan01/07/2017ApprovedfMRI
594DTI01/12/2017ApprovedfMRI
helpcenter.collection.experiments-tab

NDA Help Center

Collection - Experiments

The number of Experiments included is displayed in parentheses next to the tab name. You may download all experiments associated with the Collection via the Download button. You may view individual experiments by clicking the Experiment Name and add them to the Filter Cart via the Add to Cart button.

Collection Owners, Program Officers, and users with Submission or Administrative Privileges for the Collection may create or edit an Experiment.

Please note: The creation of an NDA Experiment does not necessarily mean that data collected, according to the defined Experiment, has been submitted or shared.

Frequently Asked Questions

  • Can an Experiment be associated with more than one Collection?

    Yes -see the “Copy” button in the bottom left when viewing an experiment. There are two actions that can be performed via this button:

    1. Copy the experiment with intent for modifications.
    2. Associate the experiment to the collection. No modifications can be made to the experiment.

Glossary

  • Experiment Status
    An Experiment must be Approved before data using the associated Experiment_ID may be uploaded.
  • Experiment ID
    The ID number automatically generated by NDA which must be included in the appropriate file when uploading data to link the Experiment Definition to the subject record.
A Developmental NEuroPSYchological Assessment (NEPSY-II) Clinical Assessments 221
Center for Epidemiologic Studies Depression Scale (CES-D) Clinical Assessments 220
Chaos Scale Clinical Assessments 227
Child Abuse Potential Inventory Clinical Assessments 225
Child Behavior Checklist (CBCL) 6-18 Clinical Assessments 226
Childhood Experience of Care and Abuse Questionnaire Clinical Assessments 216
Childhood Trauma Questionnaire Clinical Assessments 227
Children's Behavior Questionnaire Parent Clinical Assessments 224
Children's Depression Inventory 2 Clinical Assessments 227
Color Reading Interference (Stroop) Clinical Assessments 203
Conflict Tactics Scale Clinical Assessments 226
Dimensional Change Card Sort Test (DCCS) Clinical Assessments 212
Dot Probe Task Imaging 215
Emotional Stroop Task Imaging 212
Family Routines Inventory Clinical Assessments 226
HOME Interview Clinical Assessments 227
Image Imaging 182
Juvenile Victimization Questionnaire Clinical Assessments 227
Kiddie-Sads Summary Diagnoses Clinical Assessments 223
Multidimensional Neglectful Behavior Scale Clinical Assessments 222
PTSD Reaction Index for Children/Adolescents for DSM-5 Clinical Assessments 227
Pinata Task Imaging 210
Positive and Negative Affect Schedule (PANAS) Child Version Clinical Assessments 225
Research Subject Clinical Assessments 227
Response Style Questionnaire Clinical Assessments 212
Screen for Child Anxiety Related Disorders (SCARED), Parent/Child Clinical Assessments 227
Sleep Assessment Clinical Assessments 216
Tanner Sexual Maturity Scale Clinical Assessments 227
Theory of Mind Task TOM Imaging 203
Violence Exposure Scale for Children Clinical Assessments 224
WASI-2 Clinical Assessments 227
Youth Self Report Clinical Assessments 227
helpcenter.collection.shared-data-tab

NDA Help Center

Collection - Shared Data

This tab provides a quick overview of the Data Structure title, Data Type, and Number of Subjects that are currently Shared for the Collection. The information presented in this tab is automatically generated by NDA and cannot be edited. If no information is visible on this tab, this would indicate the Collection does not have shared data or the data is private.

The shared data is available to other researchers who have permission to access data in the Collection's designated Permission Group(s). Use the Download button to get all shared data from the Collection to the Filter Cart.

Frequently Asked Questions

  • How will I know if another researcher uses data that I shared through the NIMH Data Archive (NDA)?
    To see what data your project have submitted are being used by a study, simply go the Associated Studies tab of your collection. Alternatively, you may review an NDA Study Attribution Report available on the General tab.
  • Can I get a supplement to share data from a completed research project?
    Often it becomes more difficult to organize and format data electronically after the project has been completed and the information needed to create a GUID may not be available; however, you may still contact a program staff member at the appropriate funding institution for more information.
  • Can I get a supplement to share data from a research project that is still ongoing?
    Unlike completed projects where researchers may not have the information needed to create a GUID and/or where the effort needed to organize and format data becomes prohibitive, ongoing projects have more of an opportunity to overcome these challenges. Please contact a program staff member at the appropriate funding institution for more information.

Glossary

  • Data Structure
    A defined organization and group of Data Elements to represent an electronic definition of a measure, assessment, questionnaire, or collection of data points. Data structures that have been defined in the NDA Data Dictionary are available at https://nda.nih.gov/general-query.html?q=query=data-structure
  • Data Type
    A grouping of data by similar characteristics such as Clinical Assessments, Omics, or Neurosignal data.
  • Shared
    The term 'Shared' generally means available to others; however, there are some slightly different meanings based on what is Shared. A Shared NDA Study is viewable and searchable publicly regardless of the user's role or whether the user has an NDA account. A Shared NDA Study does not necessarily mean that data used in the NDA Study have been shared as this is independently determined. Data are shared according the schedule defined in a Collection's Data Expected Tab and/or in accordance with data sharing expectations in the NDA Data Sharing Terms and Conditions. Additionally, Supporting Documentation uploaded to a Collection may be shared independent of whether data are shared.

Collection Owners and those with Collection Administrator permission, may edit a collection. The following is currently available for Edit on this page:

Publications

Publications relevant to NDA data are listed below. Most displayed publications have been associated with the grant within Pubmed. Use the "+ New Publication" button to add new publications. Publications relevant/not relevant to data expected are categorized. Relevant publications are then linked to the underlying data by selecting the Create Study link. Study provides the ability to define cohorts, assign subjects, define outcome measures and lists the study type, data analysis and results. Analyzed data and results are expected in this way.

PubMed IDStudyTitleJournalAuthorsDateStatus
40207682Create StudyResearch Review: Assessment of early-life adversity and trauma - cumulative risk and dimensional approaches.Journal of child psychology and psychiatry, and allied disciplinesMachlin, Laura; Sheridan, Margaret A; Tsai, Angelina Pei-Tzu; McLaughlin, Katie ANovember 1, 2025Not Determined
39753729Create StudyDifferential gray matter correlates and machine learning prediction of abuse and internalizing psychopathology in adolescent females.Scientific reportsHeyn, Sara A; Keding, Taylor J; Cisler, Josh; McLaughlin, Katie; Herringa, Ryan JJanuary 3, 2025Not Determined
39625804Create StudyAnnual Research Review: Associations of socioeconomic status with cognitive function, language ability, and academic achievement in youth: a systematic review of mechanisms and protective factors.Journal of child psychology and psychiatry, and allied disciplinesRakesh, Divyangana; Lee, Paris Anne; Gaikwad, Amruta; McLaughlin, Katie AApril 1, 2025Not Determined
39478358Create StudyIdentifying cognitive, affective, and developmental mechanisms linking threat and deprivation with adolescent psychopathology.Journal of child psychology and psychiatry, and allied disciplinesSadikova, Ekaterina; Weissman, David G; Rosen, Maya L; Robinson, Elise; Lengua, Liliana J; Sheridan, Margaret A; Tiemeier, Henning; McLaughlin, Katie AMay 1, 2025Not Determined
39467022Create StudyEarly-life threat and deprivation: Are children similarly affected by exposure to each?Child developmentSayler, Kristina; McLaughlin, Katie A; Belsky, JayJanuary 1, 2025Not Determined
39374138Create StudyPerceptual sensitivity to labeling stereotyped emotion expressions: Associations with age and subclinical psychopathology symptoms from childhood through early adulthood.Emotion (Washington, D.C.)Weissman, David G; Vartiainen, Henna I; Nook, Erik C; Lambert, Hilary K; Sasse, Stephanie F; Somerville, Leah H; McLaughlin, Katie AApril 1, 2025Not Determined
39368282Create StudyBrain structures with stronger genetic associations are not less associated with family- and state-level economic contexts.Developmental cognitive neuroscienceWilliams, Camille M; Weissman, David G; Mallard, Travis T; McLaughlin, Katie A; Harden, K PaigeDecember 1, 2024Not Determined
39363710Create StudyThe role of caregiver emotion regulation in youth mental health during the COVID-19 pandemic: A longitudinal study.Development and psychopathologyKim, Stephanie Gyuri; Rodman, Alexandra M; Rosen, Maya L; Kasparek, Steven W; Mayes, Makeda; Lengua, Liliana J; Meltzoff, Andrew N; McLaughlin, Katie AAugust 1, 2025Not Determined
39245946Create StudyAlterations in fear learning as a mechanism linking childhood exposure to violence with PTSD symptoms: a longitudinal study.Psychological medicineMachlin, Laura; Sheridan, Margaret A; Lurie, Lucy A; Kasparek, Steven W; Kim, Stephanie Gyuri; Peverill, Matthew; France, John McClellan; Robertson, Madeline M; Jovanovic, Tanja; Lengua, Liliana J; McLaughlin, Katie ASeptember 9, 2024Not Determined
39006919Create StudyFamily income is not significantly associated with T1w/T2w ratio in the Human Connectome Project in Development.Imaging neuroscience (Cambridge, Mass.)Weissman, David G; Baum, Graham L; Sanders, Ashley; Rosen, Maya L; Barch, Deanna M; McLaughlin, Katie A; Somerville, Leah HJanuary 1, 2023Not Determined
38236725Create StudyCognitive stimulation as a mechanism linking socioeconomic status and neural function supporting working memory: a longitudinal fMRI study.Cerebral cortex (New York, N.Y. : 1991)Lurie, Lucy A; Rosen, Maya L; Weissman, David G; Machlin, Laura; Lengua, Lilliana; Sheridan, Margaret A; McLaughlin, Katie AJanuary 31, 2024Not Determined
38172629Create StudyA research agenda for understanding how social inequality is linked to brain structure and function.Nature human behaviourHatzenbuehler, Mark L; McLaughlin, Katie A; Weissman, David G; Cikara, MinaJanuary 1, 2024Not Determined
37916808Create StudyAssociations Between Structural Stigma and Psychopathology Among Early Adolescents.Journal of clinical child and adolescent psychology : the official journal for the Society of Clinical Child and Adolescent Psychology, American Psychological Association, Division 53Martino, Rachel M; Weissman, David G; McLaughlin, Katie A; Hatzenbuehler, Mark LJanuary 1, 2025Not Determined
37581854Create StudyChallenges with Latent Variable Approaches to Operationalizing Dimensions of Childhood adversity - a Commentary on Sisitsky et al. (2023).Research on child and adolescent psychopathologyMcLaughlin, Katie A; Weissman, David G; Flournoy, JohnDecember 1, 2023Not Determined
37554120Create StudyDoes reward processing moderate or mediate the link between childhood adversity and psychopathology: A longitudinal study.Development and psychopathologyKasparek, Steven W; Gastón-Panthaki, Aria; Hanford, Lindsay C; Lengua, Liliana J; Sheridan, Margaret A; McLaughlin, Katie ADecember 1, 2023Not Determined
37429074Create StudyPre-pandemic brain structure and function and adolescent psychopathology during the COVID-19 pandemic.Current opinion in psychologyMachlin, Laura; McLaughlin, Katie AAugust 1, 2023Not Determined
37226555Create StudyConversation disruptions in early childhood predict executive functioning development: A longitudinal study.Developmental scienceCarolus, Amy E; McLaughlin, Katie A; Lengua, Lilliana J; Rowe, Meredith L; Sheridan, Margaret A; Zalewski, Maureen; Moran, Lyndsey; Romeo, Rachel RJanuary 1, 2024Not Determined
37179140Create StudyChildhood socioeconomic status and the pace of structural neurodevelopment: accelerated, delayed, or simply different?Trends in cognitive sciencesRakesh, Divyangana; Whittle, Sarah; Sheridan, Margaret A; McLaughlin, Katie ASeptember 1, 2023Not Determined
37150584Create StudyWhat Is Not Measured Cannot Be Counted: Sample Characteristics Reported in Studies of Hippocampal Volume and Depression in Neuroimaging Studies.Biological psychiatry. Cognitive neuroscience and neuroimagingKeyes, Katherine M; Kreski, Noah T; Joseph, Victoria A; Hamilton, Ava D; Hatzenbuehler, Mark L; McLaughlin, Katie A; Weissman, David GMay 1, 2023Not Determined
37130880Create StudyState-level macro-economic factors moderate the association of low income with brain structure and mental health in U.S. children.Nature communicationsWeissman, David G; Hatzenbuehler, Mark L; Cikara, Mina; Barch, Deanna M; McLaughlin, Katie AMay 2, 2023Not Determined
36862283Create StudyDifferentiating Between Us & Them: Reduced In-Group Bias as a Novel Mechanism Linking Childhood Violence Exposure with Internalizing Psychopathology.Research on child and adolescent psychopathologyKasparek, Steven W; Rosen, Maya L; Lurie, Lucy A; Cikara, Mina; Sambrook, Kelly; Cvencek, Dario; Meltzoff, Andrew N; McLaughlin, Katie AJuly 1, 2023Not Determined
36640624Create StudyChildhood trauma, earlier pubertal timing, and psychopathology in adolescence: The role of corticolimbic development.Developmental cognitive neuroscienceColich, Natalie L; Hanford, Lindsay C; Weissman, David G; Allen, Nicholas B; Shirtcliff, Elizabeth A; Lengua, Liliana J; Sheridan, Margaret A; McLaughlin, Katie AFebruary 1, 2023Not Determined
36563460Create StudyChildhood trauma and brain structure in children and adolescents.Developmental cognitive neurosciencePeverill, Matthew; Rosen, Maya L; Lurie, Lucy A; Sambrook, Kelly A; Sheridan, Margaret A; McLaughlin, Katie AFebruary 1, 2023Not Determined
36529620Create StudyDimensions of Early Adversity and Sexual Behavior in a US Population-Based Adolescent Sample.The Journal of adolescent health : official publication of the Society for Adolescent MedicineThomas, Jordan L; Colich, Natalie L; McLaughlin, Katie A; Sumner, Jennifer AApril 1, 2023Not Determined
36503551Create StudySocial experiences and youth psychopathology during the COVID-19 pandemic: A longitudinal study.Development and psychopathologyRodman, Alexandra M; Rosen, Maya L; Kasparek, Steven W; Mayes, Makeda; Lengua, Liliana; Meltzoff, Andrew N; McLaughlin, Katie AFebruary 1, 2024Not Determined
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29196032Create StudyCurrent methods and limitations for longitudinal fMRI analysis across development.Developmental cognitive neuroscienceMadhyastha, Tara; Peverill, Matthew; Koh, Natalie; McCabe, Connor; Flournoy, John; Mills, Kate; King, Kevin; Pfeifer, Jennifer; McLaughlin, Katie AOctober 2018Not Relevant
29162183Create StudyDimensions of childhood adversity have distinct associations with neural systems underlying executive functioning.Development and psychopathologySheridan, Margaret A; Peverill, Matthew; Finn, Amy S; McLaughlin, Katie ADecember 2017Not Relevant
29144224Create StudyViolence exposure and neural systems underlying working memory for emotional stimuli in youth.Development and psychopathologyJenness, Jessica L; Rosen, Maya L; Sambrook, Kelly A; Dennison, Meg J; Lambert, Hilary K; Sheridan, Margaret A; McLaughlin, Katie AOctober 2018Not Relevant
29097401Create StudySensitive periods for the effect of childhood interpersonal violence on psychiatric disorder onset among adolescents.The British journal of psychiatry : the journal of mental scienceDunn EC, Wang Y, Tse J, Mclaughlin KA, Fitzmaurice G, Gilman SE, Susser ESDecember 2017Not Relevant
29064341Create StudyThe Role of Visual Association Cortex in Associative Memory Formation across Development.Journal of cognitive neuroscienceRosen ML, Sheridan MA, Sambrook KA, Peverill MR, Meltzoff AN, Mclaughlin KAOctober 2017Not Relevant
29046891Create StudyNeurobiological Models of the Impact of Adversity on Education.Current opinion in behavioral sciencesSheridan, Margaret A; McLaughlin, Katie AAugust 2016Not Relevant
29026076Create StudySample composition alters associations between age and brain structure.Nature communicationsLewinn KZ, Sheridan MA, Keyes KM, Hamilton A, Mclaughlin KAOctober 2017Relevant
28935660Create StudyChildhood adversities and post-traumatic stress disorder: evidence for stress sensitisation in the World Mental Health Surveys.The British journal of psychiatry : the journal of mental scienceMclaughlin KA, Koenen KC, Bromet EJ, Karam EG, Liu H, Petukhova M, Ruscio AM, Sampson NA, Stein DJ, Aguilar-Gaxiola S, Alonso J, Borges G, Demyttenaere K, Dinolova RV, Ferry F, Florescu S, De Girolamo G, Gureje O, Kawakami N, Lee S, Navarro-Mateu F, Piazza M, Pennell BE, Posada-Villa J, Ten Have M, et al.November 2017Not Relevant
28867878Create StudyChildhood Maltreatment and Health Impact: The Examples of Cardiovascular Disease and Type 2 Diabetes Mellitus in Adults.Clinical psychology : a publication of the Division of Clinical Psychology of the American Psychological AssociationBasu, Archana; McLaughlin, Katie A; Misra, Supriya; Koenen, Karestan CJune 2017Not Relevant
28838580Create StudyTrauma Exposure and Externalizing Disorders in Adolescents: Results From the National Comorbidity Survey Adolescent Supplement.Journal of the American Academy of Child and Adolescent PsychiatryCarliner H, Gary D, Mclaughlin KA, Keyes KMSeptember 2017Not Relevant
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28117057Create StudyMental Health and Self-Worth in Socially Transitioned Transgender Youth.Journal of the American Academy of Child and Adolescent PsychiatryDurwood L, Mclaughlin KA, Olson KRFebruary 2017Not Relevant
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28030746Create StudyAssociation of Fluid Intelligence and Psychiatric Disorders in a Population-Representative Sample of US Adolescents.JAMA psychiatryKeyes KM, Platt J, Kaufman AS, Mclaughlin KADecember 2016Not Relevant
27868085Create StudyChild Trauma Exposure and Psychopathology: Mechanisms of Risk and Resilience.Current opinion in psychologyMcLaughlin, Katie A; Lambert, Hilary KApril 2017Not Relevant
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27814521Create StudyThe Central Nervous System and the Gut Microbiome.CellSharon, Gil; Sampson, Timothy R; Geschwind, Daniel H; Mazmanian, Sarkis KNovember 2016Not Determined
27773969Create StudyBeyond Cumulative Risk: A Dimensional Approach to Childhood Adversity.Current directions in psychological scienceMcLaughlin, Katie A; Sheridan, Margaret AAugust 2016Not Relevant
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27763991Create StudyMechanisms Underlying the Association Between Early-Life Adversity and Physical Health: Charting a Course for the Future.Psychosomatic medicineBush, Nicole R; Lane, Richard D; McLaughlin, Katie A2016Not Relevant
27759442Create StudyEvidence Base Update for Psychosocial Treatments for Children and Adolescents Exposed to Traumatic Events.Journal of clinical child and adolescent psychology : the official journal for the Society of Clinical Child and Adolescent Psychology, American Psychological Association, Division 53Dorsey, Shannon; McLaughlin, Katie A; Kerns, Suzanne E U; Harrison, Julie P; Lambert, Hilary K; Briggs, Ernestine C; Revillion Cox, Julia; Amaya-Jackson, LisaMay 2017Not Relevant
27568327Create StudyCardiovascular reactivity as a mechanism linking child trauma to adolescent psychopathology.Biological psychologyHeleniak C, Mclaughlin KA, Ormel J, Riese HOctober 2016Not Relevant
27557454Create StudyCatastrophizing, rumination, and reappraisal prospectively predict adolescent PTSD symptom onset following a terrorist attack.Depression and anxietyJenness, Jessica L; Jager-Hyman, Shari; Heleniak, Charlotte; Beck, Aaron T; Sheridan, Margaret A; McLaughlin, Katie ANovember 2016Not Relevant
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27365304Create StudyAuthor Response to McKean, Vande Voort, and Croarkin (2016).PediatricsOlson KR, Durwood L, Demeules M, Mclaughlin KAJuly 2016Not Relevant
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helpcenter.collection.publications-tab

NDA Help Center

Collection - Publications

The number of Publications is displayed in parentheses next to the tab name. Clicking on any of the Publication Titles will open the Publication in a new internet browsing tab.

Collection Owners, Program Officers, and users with Submission or Administrative Privileges for the Collection may mark a publication as either Relevant or Not Relevant in the Status column.

Frequently Asked Questions

  • How can I determine if a publication is relevant?
    Publications are considered relevant to a collection when the data shared is directly related to the project or collection.
  • Where does the NDA get the publications?
    PubMed, an online library containing journals, articles, and medical research. Sponsored by NiH and National Library of Medicine (NLM).

Glossary

  • Create Study
    A link to the Create an NDA Study page that can be clicked to start creating an NDA Study with information such as the title, journal and authors automatically populated.
  • Not Determined Publication
    Indicates that the publication has not yet been reviewed and/or marked as Relevant or Not Relevant so it has not been determined whether an NDA Study is expected.
  • Not Relevant Publication
    A publication that is not based on data related to the aims of the grant/project associated with the Collection or not based on any data such as a review article and, therefore, an NDA Study is not expected to be created.
  • PubMed
    PubMed provides citation information for biomedical and life sciences publications and is managed by the U.S. National Institutes of Health's National Library of Medicine.
  • PubMed ID
    The PUBMed ID is the unique ID number for the publication as recorded in the PubMed database.
  • Relevant Publication
    A publication that is based on data related to the aims of the grant/project associated with the Collection and, therefore, an NDA Study is expected to be created.
Data Expected List: Mandatory Data Structures

These data structures are mandatory for your NDA Collection. Please update the Targeted Enrollment number to accurately represent the number of subjects you expect to submit for the entire study.

For NIMH HIV-related research that involves human research participants: Select the dictionary or dictionaries most appropriate for your research. If your research does not require all three data dictionaries, just ignore the ones you do not need. There is no need to delete extra data dictionaries from your NDA Collection. You can adjust the Targeted Enrollment column in the Data Expected tab to “0” for those unnecessary data dictionaries. At least one of the three data dictionaries must have a non-zero value.

Data ExpectedTargeted EnrollmentInitial SubmissionSubjects SharedStatus
Research Subject and Pedigree info icon
22502/27/2017
227
Approved
To create your project's Data Expected list, use the "+New Data Expected" to add or request existing structures and to request new Data Structures that are not in the NDA Data Dictionary.

If the Structure you need already exists, locate it and specify your dates and enrollment when adding it to your Data Expected list. If you require changes to the Structure you need, select the indicator stating "No, it requires changes to meet research needs," and upload a file containing your requested changes.

If the structure you need is not yet defined in the Data Dictionary, you can select "Upload Definition" and attach the necessary materials to request its creation.

When selecting the expected dates for your data, make sure to follow the standard Data Sharing Regimen and choose dates within the date ranges that correspond to your project start and end dates.

Please visit the Completing Your Data Expected Tutorial for more information.
Data Expected List: Data Structures per Research Aims

These data structures are specific to your research aims and should list all data structures in which data will be collected and submitted for this NDA Collection. Please update the Targeted Enrollment number to accurately represent the number of subjects you expect to submit for the entire study.

Data ExpectedTargeted EnrollmentInitial SubmissionSubjects SharedStatus
Positive and Negative Affect Schedule info icon
22502/27/2017
225
Approved
Childhood Trauma Questionnaire info icon
22502/27/2017
227
Approved
Wechsler Abbreviated Scale of Intelligence (WASI) info icon
22502/27/2017
227
Approved
Center for Epidemiologic Studies Depression Scale (CES-D) info icon
22502/27/2017
220
Approved
Childrens Depression Inventory info icon
22502/27/2017
227
Approved
Child Behavior Checklist (CBCL) info icon
22502/27/2017
226
Approved
Tanner Sexual Maturity Scale info icon
22502/27/2017
227
Approved
Screen for Childhood Anxiety Related Emotional Disorders (SCARED) info icon
22502/27/2017
227
Approved
Response Style Questionnaire info icon
22502/27/2017
212
Approved
NEPSY info icon
22502/27/2017
221
Approved
Childrens Behavior Questionnaire (CBQ) info icon
22502/27/2017
224
Approved
Kiddie-Sads (K-SADS) info icon
22502/27/2017
223
Approved
Child Abuse Potential Inventory info icon
22502/27/2017
225
Approved
Childhood Experiences of Care and Abuse Interview info icon
22502/27/2017
216
Approved
HOME Interview info icon
22502/27/2017
227
Approved
Youth Self Report info icon
22502/27/2017
227
Approved
Violence Exposure Scale for Children info icon
22502/27/2017
224
Approved
Color Reading Interference (Stroop) info icon
22502/27/2017
203
Approved
Conflict Tactics Scale info icon
22502/27/2017
226
Approved
Imaging (Structural, fMRI, DTI, PET, microscopy) info icon
20005/15/2017
182
Approved
Dimensional Change Card Sort Test info icon
22502/27/2017
212
Approved
PTSD Reaction Index for Children/Adolescents for DSM-5 info icon
22502/27/2017
227
Approved
Chaos Scale info icon
22502/27/2017
227
Approved
Juvenile Victimization Questionnaire info icon
22502/27/2017
227
Approved
Multidimensional Neglectful Behaviors Scale info icon
22502/27/2017
222
Approved
Sleep Assessment info icon
22502/27/2017
216
Approved
Family Routines Inventory info icon
22502/27/2017
226
Approved
Theory of Mind Task info icon
22502/27/2017
203
Approved
Pinata Task info icon
22502/27/2017
210
Approved
Emotional Stroop Task info icon
22502/27/2017
212
Approved
Dot Probe Task info icon
22502/27/2017
215
Approved
Structure not yet defined
No Status history for this Data Expected has been recorded yet
helpcenter.collection.data-expected-tab

NDA Help Center

Collection - Data Expected

The Data Expected tab displays the list of all data that NDA expects to receive in association with the Collection as defined by the contributing researcher, as well as the dates for the expected initial upload of the data, and when it is first expected to be shared, or with the research community. Above the primary table of Data Expected, any publications determined to be relevant to the data within the Collection are also displayed - members of the contributing research group can use these to define NDA Studies, connecting those papers to underlying data in NDA.

The tab is used both as a reference for those accessing shared data, providing information on what is expected and when it will be shared, and as the primary tracking mechanism for contributing projects. It is used by both contributing primary researchers, secondary researchers, and NIH Program and Grants Management staff.

Researchers who are starting their project need to update their Data Expected list to include all the Data Structures they are collecting under their grant and set their initial submission and sharing schedule according to the NDA Data Sharing Regimen.

To add existing Data Structures from the Data Dictionary, to request new Data Structure that are not in the Dictionary, or to request changes to existing Data Structures, click "+New Data Expected".

For step-by-step instructions on how to add existing Data Structures, request changes to an existing Structure, or request a new Data Structure, please visit the Completing Your Data Expected Tutorial.

If you are a contributing researcher creating this list for the first time, or making changes to the list as your project progress, please note the following:

  • Although items you add to the list and changes you make are displayed, they are not committed to the system until you Save the entire page using the "Save" button at the bottom of your screen. Please Save after every change to ensure none of your work is lost.
  • If you attempt to add a new structure, the title you provide must be unique - if another structure exists with the same name your change will fail.
  • Adding a new structure to this list is the only way to request the creation of a new Data Dictionary definition.

Frequently Asked Questions

  • What is an NDA Data Structure?
    An NDA Data Structure is comprised of multiple Data Elements to make up an electronic definition of an assessment, measure, questionnaire, etc will have a corresponding Data Structure.
  • What is the NDA Data Dictionary?
    The NDA Data Dictionary is comprised of electronic definitions known as Data Structures.

Glossary

  • Analyzed Data
    Data specific to the primary aims of the research being conducted (e.g. outcome measures, other dependent variables, observations, laboratory results, analyzed images, volumetric data, etc.) including processed images.
  • Data Item
    Items listed on the Data Expected list in the Collection which may be an individual and discrete Data Structure, Data Structure Category, or Data Structure Group.
  • Data Structure
    A defined organization and group of Data Elements to represent an electronic definition of a measure, assessment, questionnaire, or collection of data points. Data structures that have been defined in the NDA Data Dictionary are available at https://nda.nih.gov/general-query.html?q=query=data-structure
  • Data Structure Category
    An NDA term describing the affiliation of a Data Structure to a Category, which may be disease/disorder or diagnosis related (Depression, ADHD, Psychosis), specific to data type (MRI, eye tracking, omics), or type of data (physical exam, IQ).
  • Data Structure Group
    A Data Item listed on the Data Expected tab of a Collection that indicates a group of Data Structures (e.g., ADOS or SCID) for which data may be submitted instead of a specific Data Structure identified by version, module, edition, etc. For example, the ADOS Data Structure Category includes every ADOS Data Structure such as ADOS Module 1, ADOS Module 2, ADOS Module 1 - 2nd Edition, etc. The SCID Data Structure Group includes every SCID Data Structure such as SCID Mania, SCID V Mania, SCID PTSD, SCID-V Diagnosis, and more.
  • Evaluated Data
    A new Data Structure category, Evaluated Data is analyzed data resulting from the use of computational pipelines in the Cloud and can be uploaded directly back to a miNDAR database. Evaluated Data is expected to be listed as a Data Item in the Collection's Data Expected Tab.
  • Imaging Data
    Imaging+ is an NDA term which encompasses all imaging related data including, but not limited to, images (DTI, MRI, PET, Structural, Spectroscopy, etc.) as well as neurosignal data (EEG, fMRI, MEG, EGG, eye tracking, etc.) and Evaluated Data.
  • Initial Share Date
    Initial Submission and Initial Share dates should be populated according to the NDA Data Sharing Terms and Conditions. Any modifications to these will go through the approval processes outlined above. Data will be shared with authorized users upon publication (via an NDA Study) or 1-2 years after the grant end date specified on the first Notice of Award, as defined in the applicable Data Sharing Terms and Conditions.
  • Initial Submission Date
    Initial Submission and Initial Share dates should be populated according to these NDA Data Sharing Terms and Conditions. Any modifications to these will go through the approval processes outlined above. Data for all subjects is not expected on the Initial Submission Date and modifications may be made as necessary based on the project's conduct.
  • Research Subject and Pedigree
    An NDA created Data Structure used to convey basic information about the subject such as demographics, pedigree (links family GUIDs), diagnosis/phenotype, and sample location that are critical to allow for easier querying of shared data.
  • Submission Cycle
    The NDA has two Submission Cycles per year - January 15 and July 15.
  • Submission Exemption
    An interface to notify NDA that data may not be submitted during the upcoming/current submission cycle.

Collection Owners and those with Collection Administrator permission, may edit a collection. The following is currently available for Edit on this page:

Associated Studies

Studies that have been defined using data from a Collection are important criteria to determine the value of data shared. The number of subjects column displays the counts from this Collection that are included in a Study, out of the total number of subjects in that study. The Data Use column represents whether or not the study is a primary analysis of the data or a secondary analysis. State indicates whether the study is private or shared with the research community.

Study NameDOIAbstractCollection/Study SubjectsData UsageState
No records found.
helpcenter.collection.associated-studies-tab

NDA Help Center

Collection - Associated Studies

Clicking on the Study Title will open the study details in a new internet browser tab. The Abstract is available for viewing, providing the background explanation of the study, as provided by the Collection Owner.

Primary v. Secondary Analysis: The Data Usage column will have one of these two choices. An associated study that is listed as being used for Primary Analysis indicates at least some and potentially all of the data used was originally collected by the creator of the NDA Study. Secondary Analysis indicates the Study owner was not involved in the collection of data, and may be used as supporting data.

Private v. Shared State: Studies that remain private indicate the associated study is only available to users who are able to access the collection. A shared study is accessible to the general public.

Frequently Asked Questions

  • How do I associate a study to my collection?
    Studies are associated to the Collection automatically when the data is defined in the Study.

Glossary

  • Associated Studies Tab
    A tab in a Collection that lists the NDA Studies that have been created using data from that Collection including both Primary and Secondary Analysis NDA Studies.
Edit