NIMH Data Archive - Data

Genomics

Neuroimaging

Phenotype¹

New Trial
Clinical Trial

¹ Numbers reported are subjects by age

New Project
Grant/Project Number

Format should be in the following format: Activity Code, Institute Abbreviation, and Serial Number. Grant Type, Support Year, and Suffix should be excluded. For example, grant 1R01MH123456-01A1 should be entered R01MH123456

Collection - Use Existing Experiment

To associate an experiment to the current collection, just select an axperiment from the table below then click the associate experiment button to persist your changes (saving the collection is not required). Note that once an experiment has been associated to two or more collections, the experiment will not longer be editable.

The table search feature is case insensitive and targets the experiment id, experiment name and experiment type columns. The experiment id is searched only when the search term entered is a number, and filtered using a startsWith comparison. When the search term is not numeric the experiment name is used to filter the results.

Select	Experiment Id	Experiment Name	Experiment Type	Created On

24	HI-NGS_R1	Omics	02/16/2011
475	MB1-10 (CHOP)	Omics	06/07/2016
490	Discovery and CRISPR validation of genetic factors associated with antipsychotic-induced weight gain and cardiometabolic risk	Omics	07/07/2016
501	PharmacoBOLD Resting State	fMRI	07/27/2016
506	PVPREF	Omics	08/05/2016
509	ABC-CT Resting v2	EEG	08/18/2016
13	Comparison of FI expression in Autistic and Neurotypical Homo Sapiens	Omics	12/28/2010
18	AGRE/Broad Affymetrix 5.0 Genotype Experiment	Omics	01/06/2011
22	Stitching PCR Sequencing	Omics	02/14/2011
26	ASD_Methylation	Omics	03/01/2011
29	Microarray family 03 (father, mother, sibling)	Omics	03/24/2011
37	Standard paired-end sequencing of BCRs	Omics	04/19/2011
38	Illumina Mate-Pair BCR sequencing	Omics	04/19/2011
39	Custom Jumping Libraries	Omics	04/19/2011
40	Custom CapBP	Omics	04/19/2011
41	Immunofluorescence	Omics	05/11/2011
43	Autism brain sample genotyping, Illumina	Omics	05/16/2011
47	ARRA Autism Sequencing Collaboration at Baylor. SOLiD 4 System	Omics	08/01/2011
53	AGRE Omni1-quad	Omics	10/11/2011
59	AGP genotyping	Omics	04/03/2012
60	Ultradeep 454 sequencing of synaptic genes from postmortem cerebella of individuals with ASD and neurotypical controls	Omics	06/23/2012
63	Microemulsion PCR and Targeted Resequencing for Variant Detection in ASD	Omics	07/20/2012
76	Whole Genome Sequencing in Autism Families	Omics	01/03/2013
519	Resting	fMRI	11/08/2016
90	Genotyped IAN Samples	Omics	07/09/2013
91	NJLAGS Axiom Genotyping Array	Omics	07/16/2013
93	AGP genotyping (CNV)	Omics	09/06/2013
106	Longitudinal Sleep Study. H20 200. Channel set 2	EEG	11/07/2013
107	Longitudinal Sleep Study. H20 200. Channel set 3	EEG	11/07/2013
108	Longitudinal Sleep Study. AURA 200	EEG	11/07/2013
105	Longitudinal Sleep Study. H20 200. Channel set 1	EEG	11/07/2013
109	Longitudinal Sleep Study. AURA 400	EEG	11/07/2013
116	Gene Expression Analysis WG-6	Omics	01/07/2014
131	Jeste Lab UCLA ACEii: Charlie Brown and Sesame Street - Project 1	Eye Tracking	02/27/2014
132	Jeste Lab UCLA ACEii: Animacy - Project 1	Eye Tracking	02/27/2014
133	Jeste Lab UCLA ACEii: Mom Stranger - Project 2	Eye Tracking	02/27/2014
134	Jeste Lab UCLA ACEii: Face Emotion - Project 3	Eye Tracking	02/27/2014
145	AGRE/FMR1_Illumina.JHU	Omics	04/14/2014
146	AGRE/MECP2_Sanger.JHU	Omics	04/14/2014
147	AGRE/MECP2_Junior.JHU	Omics	04/14/2014
151	Candidate Gene Identification in familial Autism	Omics	06/09/2014
152	NJLAGS Whole Genome Sequencing	Omics	07/01/2014
154	Math Autism Study - Vinod Menon	fMRI	07/15/2014
155	Resting	fMRI	07/25/2014
156	Speech	fMRI	07/25/2014
159	Emotion	fMRI	07/25/2014
160	syllable contrast	EEG	07/29/2014
167	School-age naturalistic stimuli	Eye Tracking	09/19/2014
44	AGRE/Broad Affymetrix 5.0 Genotype Experiment	Omics	06/27/2011
45	Exome Sequencing of 20 Sporadic Cases of Autism Spectrum Disorder	Omics	07/15/2011

Collection - Add Experiment

Add Supporting Documentation

Funding Source:
URL:

To add an existing Data Structure, enter its title in the search bar. If you need to request changes, select the indicator "No, it requires changes to meet research needs" after selecting the Structure, and upload the file with the request changes specific to the selected Data Structure. Your file should follow the Request Changes Procedure. If the Data Structure does not exist, select "Request New Data Structure" and upload the appropriate zip file.

Use/Modify Existing Data Structure

Request New Data Structure

Targeted Enrollment:

Initial Submission Date:

Initial Share Date:

Data Structure Search:

Data Structures:

Submit

Request Submission Exemption

Not Eligible

The Data Expected list for this Collection shows some raw data as missing. Contact the NDA Help Desk with any questions.

Please confirm that you will not be enrolling any more subjects and that all raw data has been collected and submitted.

Collection Updated

Your Collection is now in Data Analysis phase and exempt from biannual submissions. Analyzed data is still expected prior to publication or no later than the project end date.

[CMS] Error

[CMS]

Unable to change collection phase where targeted enrollment is less than 90%

You have requested to move the sharing dates for the following assessments:

Data Expected Item	Original Sharing Date	New Sharing Date

Please provide a reason for this change, which will be sent to the Program Officers listed within this collection:

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Longitudinal Assessment of Post-traumatic Syndromes. AURORA Project #2526

General
Experiments (8)
Shared Data
Publications (83)
Data Expected (123)
Associated Studies (7)

Collection Title	Collection Investigators	Collection Description
Collection Title:	Longitudinal Assessment of Post-traumatic Syndromes. AURORA Project
Collection Investigators:	Samuel Mclean
Collection Description:	Each year, more than 40 million Americans present to US emergency departments EDs for evaluation after trauma exposure TE. While the majority of these individuals recover, an important subset develops adverse posttraumatic neuropsychiatric sequel ae APNS. These APNS include traditionally categorized outcomes such as posttraumatic stress disorder PTSD, depression, minor traumatic brain injury MTBI, and regional or widespread pain. However, these previous definitions of outcome have limited progress, and we now appreciate that the actual trajectories of APNS are multidimensional, incorporating a range of specific outcomes that may be best understood, and optimally targeted for intervention, by dividing across specific domains of functioning. This application, submitted in response to RFA-MH-16-500, proposes to identify and characterize the trajectories of the most common trauma-induced APNS within these domains of functioning using the RDoC classification system. 5,000 patients presenting to the ED after trauma will be screened, recruited, and will receive initial baseline evaluation in the ED, including blood collection and psychophysical, survey, and neurocognitive evaluation. They will be closely monitored over the next 8 weeks using innovative technologies a wrist wearable for continuous-time monitoring of daytime physiology and sleep a smart phone app for continuous-time monitoring of GPS and daily flash surveys weekly web-based neurocognitive tests periodic mixed-mode surveys serial saliva collection deep phenotyping blood collection, fMRI, psychophysical evaluation and then followed less intensively using similar procedures including deep phenotyping over the remainder of a 52-week follow-up period. Adaptive sampling and state-of-the-art statistical methods will be used to 1 optimize precision in characterizing RDoC construct trajectories and 2 test theoretically-guided, high yield hypotheses evaluating the effects of pre-trauma, peritraumatic, and recovery-related factors on these trajectories and on multivariate RDoC construct trajectory profiles. The longitudinal schedule of rich, granular, multidimensional data collection in the study has been specifically designed to evaluate those constructs most important to post-TE outcomes and to test the proposed hypotheses. Ensemble machine learning methods will be used to develop tiered-targeted clinical decision support models to identify individuals at high risk of specific, common APNS outcomes. The close-knit ED research network that will undertake the study has a strong track record of prospective research on APNS and is ideally suited to carry out this exceedingly complex study. The study has been designed to be a resource for the entire field for example, it has been designed and budgeted to collect and store a great many more biological samples at the NIMH Biorespository than we can analyze, for use by other investigators.
Data Repository:	NIMH Data Archive
Permission Group:
Collection Creation Date:	09/30/2016
NIH Research Initiative:	NIMH Repository & Genomics Resource (NRGR)
Collection Phase:	Funding Completed
Collection Sub-Phase:	Close Out
Blinded Clinical Trial:	No
Total Funded Amount:	$16,378,753.00
Subjects Shared:	3,840
Collection DOI:	10.15154/my7y-qx79

{"values":[]}

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Funding Sources:

Funding Source Name	Funding Source URL
NIH - Extramural	None

Supporting Documentation:

File Name	File Type	Description	Audience
Aurora_Neurocognitive_Test_Descriptions.pdf	Software	Neurocognitive test descriptions from Test My Brain.	Qualified Researchers
Aurora_Startle_Raw_Files_Specifications_001.docx	Software	AURORA's Startle raw (and intermediate analysis files), scripts	Qualified Researchers

Grant Information:

Project Number	Title	Start Date	Original End Date	End Date	Planned Enrollment	Actual Enrollment	Organization	Funds Obligated
U01MH110925-01	Longitudinal Assessment of Post-traumatic Syndromes	09/23/2016	07/31/2021	07/31/2021	4965	3829	UNIV OF NORTH CAROLINA CHAPEL HILL	$16,378,753.00

Clinical Trials:

helpcenter.collection.general-tab

Collection - General Tab

Fields available for edit on the top portion of the page include:

Collection Title
Investigators
Collection Description
Collection Phase
Funding Source
Clinical Trials

Collection Phase: The current status of a research project submitting data to an NDA Collection, based on the timing of the award and/or the data that have been submitted.

Pre-Enrollment: The default entry made when the NDA Collection is created.
Enrolling: Data have been submitted to the NDA Collection or the NDA Data Expected initial submission date has been reached for at least one data structure category in the NDA Collection.
Data Analysis: Subject level data collection for the research project is completed and has been submitted to the NDA Collection. The NDA Collection owner or the NDA Help Desk may set this phase when they’ve confirmed data submission is complete and submitted subject counts match at least 90% of the target enrollment numbers in the NDA Data Expected. Data submission reminders will be turned off for the NDA Collection.
Funding Completed: The NIH grant award (or awards) associated with the NDA Collection has reached its end date. NDA Collections in Funding Completed phase are assigned a subphase to indicate the status of data submission.
- The Data Expected Subphase indicates that NDA expects more data will be submitted
- The Closeout Subphase indicates the data submission is complete.
- The Sharing Not Met Subphase indicates that data submission was not completed as expected.

Blinded Clinical Trial Status:

This status is set by a Collection Owner and indicates the research project is a double blinded clinical trial. When selected, the public view of Data Expected will show the Data Expected items and the Submission Dates, but the targeted enrollment and subjects submitted counts will not be displayed.
Targeted enrollment and subjects submitted counts are visible only to NDA Administrators and to the NDA Collection or as the NDA Collection Owner.
When an NDA Collection that is flagged Blinded Clinical Trial reaches the maximum data sharing date for that Data Repository (see https://nda.nih.gov/nda/sharing-regimen.html), the embargo on Data Expected information is released.

Funding Source

The organization(s) responsible for providing the funding is listed here.

Supporting Documentation

Users with Submission privileges, as well as Collection Owners, Program Officers, and those with Administrator privileges, may upload and attach supporting documentation. By default, supporting documentation is shared to the general public, however, the option is also available to limit this information to qualified researchers only.

Grant Information

Identifiable details are displayed about the Project of which the Collection was derived from. You may click in the Project Number to view a full report of the Project captured by the NIH.

Clinical Trials

Any data that is collected to support or further the research of clinical studies will be available here. Collection Owners and those with Administrator privileges may add new clinical trials.

Frequently Asked Questions

How does the NIMH Data Archive (NDA) determine which Permission Group data are submitted into?

During Collection creation, NDA staff determine the appropriate Permission Group based on the type of data to be submitted, the type of access that will be available to data access users, and the information provided by the Program Officer during grant award.
How do I know when a NDA Collection has been created?

When a Collection is created by NDA staff, an email notification will automatically be sent to the PI(s) of the grant(s) associated with the Collection to notify them.
Is a single grant number ever associated with more than one Collection?

The NDA system does not allow for a single grant to be associated with more than one Collection; therefore, a single grant will not be listed in the Grant Information section of a Collection for more than one Collection.
Why is there sometimes more than one grant included in a Collection?

In general, each Collection is associated with only one grant; however, multiple grants may be associated if the grant has multiple competing segments for the same grant number or if multiple different grants are all working on the same project and it makes sense to hold the data in one Collection (e.g., Cooperative Agreements).

Glossary

Administrator Privilege

A privilege provided to a user associated with an NDA Collection or NDA Study whereby that user can perform a full range of actions including providing privileges to other users.
Collection Owner

Generally, the Collection Owner is the contact PI listed on a grant. Only one NDA user is listed as the Collection owner. Most automated emails are primarily sent to the Collection Owner.
Collection Phase
The Collection Phase provides information on data submission as opposed to grant/project completion so while the Collection phase and grant/project phase may be closely related they are often different. Collection users with Administrative Privileges are encouraged to edit the Collection Phase. The Program Officer as listed in eRA (for NIH funded grants) may also edit this field. Changes must be saved by clicking the Save button at the bottom of the page. This field is sortable alphabetically in ascending or descending order. Collection Phase options include:
- Pre-Enrollment: A grant/project has started, but has not yet enrolled subjects.
- Enrolling: A grant/project has begun enrolling subjects. Data submission is likely ongoing at this point.
- Data Analysis: A grant/project has completed enrolling subjects and has completed all data submissions.
- Funding Completed: A grant/project has reached the project end date.
Collection Title

An editable field with the title of the Collection, which is often the title of the grant associated with the Collection.
Grant

Provides the grant number(s) for the grant(s) associated with the Collection. The field is a hyperlink so clicking on the Grant number will direct the user to the grant information in the NIH Research Portfolio Online Reporting Tools (RePORT) page.
Supporting Documentation

Various documents and materials to enable efficient use of the data by investigators unfamiliar with the project and may include the research protocol, questionnaires, and study manuals.
NIH Research Initiative

NDA Collections may be organized by scientific similarity into NIH Research Initiatives, to facilitate query tool user experience. NIH Research Initiatives map to one or multiple Funding Opportunity Announcements.
Permission Group

Access to shared record-level data in NDA is provisioned at the level of a Permission Group. NDA Permission Groups consist of one or multiple NDA Collections that contain data with the same subject consents.
Planned Enrollment

Number of human subject participants to be enrolled in an NIH-funded clinical research study. The data is provided in competing applications and annual progress reports.
Actual Enrollment

Number of human subjects enrolled in an NIH-funded clinical research study. The data is provided in annual progress reports.
NDA Collection

A virtual container and organization structure for data and associated documentation from one grant or one large project/consortium. It contains tools for tracking data submission and allows investigators to define a wide array of other elements that provide context for the data, including all general information regarding the data and source project, experimental parameters used to collect any event-based data contained in the Collection, methods, and other supporting documentation. They also allow investigators to link underlying data to an NDA Study, defining populations and subpopulations specific to research aims.
Data Use Limitations

Data Use Limitations (DULs) describe the appropriate secondary use of a dataset and are based on the original informed consent of a research participant. NDA only accepts consent-based data use limitations defined by the NIH Office of Science Policy.
Total Subjects Shared

The total number of unique subjects for whom data have been shared and are available for users with permission to access data.

Contact NDA Help Desk

ID	Name	Created Date	Status	Type
1204	AURORA_fMRI_Emory	02/11/2019	Approved	fMRI
1205	AURORA_fMRI_Mclean	02/11/2019	Approved	fMRI
1206	AURORA_fMRI_Temple	02/11/2019	Approved	fMRI
1207	AURORA_fMRI_Wayne	02/11/2019	Approved	fMRI
1519	AURORA _fMRI_WashU	01/28/2020	Approved	fMRI
2129	AURORA_GWAS	11/29/2022	Approved	Omics
3129	AURORA_RNA sequencing	01/12/2026	Approved	Omics
3188	AURORA_DNA_Methylation	02/03/2026	Approved	Omics

helpcenter.collection.experiments-tab

Collection - Experiments

The number of Experiments included is displayed in parentheses next to the tab name. You may download all experiments associated with the Collection via the Download button. You may view individual experiments by clicking the Experiment Name and add them to the Filter Cart via the Add to Cart button.

Collection Owners, Program Officers, and users with Submission or Administrative Privileges for the Collection may create or edit an Experiment.

Please note: The creation of an NDA Experiment does not necessarily mean that data collected, according to the defined Experiment, has been submitted or shared.

Frequently Asked Questions

Can an Experiment be associated with more than one Collection?
Yes -see the “Copy” button in the bottom left when viewing an experiment. There are two actions that can be performed via this button:
1. Copy the experiment with intent for modifications.
2. Associate the experiment to the collection. No modifications can be made to the experiment.

Glossary

Experiment Status

An Experiment must be Approved before data using the associated Experiment_ID may be uploaded.
Experiment ID

The ID number automatically generated by NDA which must be included in the appropriate file when uploading data to link the Experiment Definition to the subject record.

Contact NDA Help Desk

Shared Data:

Title	Type	Number of Subjects
AURORA Big Five Inventory	Clinical Assessments	3160
AURORA Keystroke Biomarker	Clinical Assessments	22
AURORA Latent Construct Pain Survey	Clinical Assessments	2626
AURORA Latent Construct Somatic Survey	Clinical Assessments	2626
AURORA Neurocognitive Assessment Emotion Recognition	Clinical Assessments	2744
AURORA Neurocognitive Assessment Vocabulary and Verbal Association	Clinical Assessments	974
AURORA Survey	Clinical Assessments	3827
AURORA Watch Activity Counts	Clinical Assessments	153
Adult ADHD Self-Report Scale Screener	Clinical Assessments	3184
Anxiety Sensitivity Index	Clinical Assessments	2899
Attitudes Towards Risk Questionnaire	Clinical Assessments	3184
Belmont Emotion Sensitivity Test	Clinical Assessments	1261
Berlin Questionnaire Sleep Apnea	Clinical Assessments	2899
Car Crash Assessment	Clinical Assessments	3827
Childhood Trauma Questionnaire	Clinical Assessments	2899
Choice Reaction Time	Clinical Assessments	2948
Circadian Energy Scale	Clinical Assessments	2899
Clinician-Administered PTSD Scale	Clinical Assessments	3827
Cognitive Bias Test	Clinical Assessments	1267
Composite International Diagnostic Interview	Clinical Assessments	3827
Connor Davidson Resilience Scale	Clinical Assessments	3099
Delay Discounting Task	Clinical Assessments	669
Digit Symbol Substitution Test	Clinical Assessments	2672
Dissociative Experiences Scale	Clinical Assessments	3827
Dot Probe Task	Imaging	1578
Drug Screen	Clinical Assessments	3797
Electro-dermal Activity	Clinical Assessments	1375
Emergency Room Chief Complaint	Clinical Assessments	3797
Emergency Room Diagnosis	Clinical Assessments	3797
Emergency Room Injuries Assessment	Clinical Assessments	3797
Emergency Room Medical History	Clinical Assessments	3797
Emergency Room Medications	Clinical Assessments	3799
Emergency Room Radiology	Clinical Assessments	3797
Emergency Room Trauma Assessment	Clinical Assessments	3827
Family History Research Diagnostic Criteria Interview	Clinical Assessments	2976
Five Facet Mindfulness Questionnaire	Clinical Assessments	3099
Forward Digit Span	Clinical Assessments	2510
Genomics Sample	Genomics	2741
Genomics Subject	Genomics	2741
Go No Go Task	Clinical Assessments	2583
Health Service Utilization	Clinical Assessments	3000
Image	Imaging	424
Implicit Association Test	Clinical Assessments	1265
Insomnia Severity Index	Clinical Assessments	3827
Life Events Checklist	Clinical Assessments	2635
List of Threatening Experiences Questionnaire	Clinical Assessments	2971
Medications	Clinical Assessments	3106
Michigan Critical Events Perception Scale	Clinical Assessments	3827
Military Service Questionnaire	Clinical Assessments	2899
Mindstrong Flash Surveys	Clinical Assessments	3370
PROMIS Emotional Distress - Depression	Clinical Assessments	3828
PROMIS Emotional Distress-Anxiety	Clinical Assessments	3827
PROMIS Self-Efficacy for Managing Emotions	Clinical Assessments	2899
PROMIS Sleep-Related Impairment	Clinical Assessments	3840
PROMIS Support	Clinical Assessments	3184
PTSD Checklist - Civilian	Clinical Assessments	3827
Pain Survey	Clinical Assessments	3827
Pain Tasks	Clinical Assessments	559
Penn Emotion Recognition Task	Clinical Assessments	2527
Pennebaker Inventory of Limbic Languidness	Clinical Assessments	3827
Perceived Stress Scale	Clinical Assessments	3827
Perception of Severity of Stress	Clinical Assessments	3827
Peritraumatic Distress Inventory	Clinical Assessments	3827
PhenX Demographics	Clinical Assessments	3827
PhenX Substance Use	Clinical Assessments	3827
Pittsburgh Sleep Quality Index	Clinical Assessments	3827
Polygenic Risk Scores	Genomics	1005
Probabilistic Reward Task	Clinical Assessments	593
Reaction Time	Clinical Assessments	854
Religiosity Form	Clinical Assessments	3160
Research Subject	Clinical Assessments	3828
Rumination-Reflection Questionnaire	Clinical Assessments	3827
Screener	Clinical Assessments	3827
Sheehan Disability Scales	Clinical Assessments	3827
Short Form Health Survey	Clinical Assessments	3827
Startle Testing Summary	Imaging	543
Ten Item Personality Measure	Clinical Assessments	3160
Threat Neutral Sternberg	Clinical Assessments	1486
Traumatic Brain Injury	Clinical Assessments	3827
UPPS Impulsive Behavior Scale	Clinical Assessments	3184
Verbal Paired Associates Memory	Clinical Assessments	2520
Vital Signs	Clinical Assessments	3797
Vocabulary Series	Clinical Assessments	743

helpcenter.collection.shared-data-tab

Collection - Shared Data

This tab provides a quick overview of the Data Structure title, Data Type, and Number of Subjects that are currently Shared for the Collection. The information presented in this tab is automatically generated by NDA and cannot be edited. If no information is visible on this tab, this would indicate the Collection does not have shared data or the data is private.

The shared data is available to other researchers who have permission to access data in the Collection's designated Permission Group(s). Use the Download button to get all shared data from the Collection to the Filter Cart.

Frequently Asked Questions

How will I know if another researcher uses data that I shared through the NIMH Data Archive (NDA)?

To see what data your project have submitted are being used by a study, simply go the Associated Studies tab of your collection. Alternatively, you may review an NDA Study Attribution Report available on the General tab.
Can I get a supplement to share data from a completed research project?

Often it becomes more difficult to organize and format data electronically after the project has been completed and the information needed to create a GUID may not be available; however, you may still contact a program staff member at the appropriate funding institution for more information.
Can I get a supplement to share data from a research project that is still ongoing?

Unlike completed projects where researchers may not have the information needed to create a GUID and/or where the effort needed to organize and format data becomes prohibitive, ongoing projects have more of an opportunity to overcome these challenges. Please contact a program staff member at the appropriate funding institution for more information.

Glossary

Data Structure

A defined organization and group of Data Elements to represent an electronic definition of a measure, assessment, questionnaire, or collection of data points. Data structures that have been defined in the NDA Data Dictionary are available at https://nda.nih.gov/general-query.html?q=query=data-structure
Data Type

A grouping of data by similar characteristics such as Clinical Assessments, Omics, or Neurosignal data.
Shared

The term 'Shared' generally means available to others; however, there are some slightly different meanings based on what is Shared. A Shared NDA Study is viewable and searchable publicly regardless of the user's role or whether the user has an NDA account. A Shared NDA Study does not necessarily mean that data used in the NDA Study have been shared as this is independently determined. Data are shared according the schedule defined in a Collection's Data Expected Tab and/or in accordance with data sharing expectations in the NDA Data Sharing Terms and Conditions. Additionally, Supporting Documentation uploaded to a Collection may be shared independent of whether data are shared.

Contact NDA Help Desk

Collection Owners and those with Collection Administrator permission, may edit a collection. The following is currently available for Edit on this page:

Publications

Publications relevant to NDA data are listed below. Most displayed publications have been associated with the grant within Pubmed. Use the "+ New Publication" button to add new publications. Publications relevant/not relevant to data expected are categorized. Relevant publications are then linked to the underlying data by selecting the Create Study link. Study provides the ability to define cohorts, assign subjects, define outcome measures and lists the study type, data analysis and results. Analyzed data and results are expected in this way.

PubMed ID	Study	Title	Journal	Authors	Date	Status
41719383	Create Study	Monocyte-derived IL-10 drives sex differences in pain duration.	Science immunology	Sim, Jaewon; O'Guin, Elizabeth; Sugimoto, Chiho; Laumet, Sophie; Monahan, Karli; Bernard, Matthew P; McLean, Samuel A; Albertorio-Sáez, Liz M; Zhao, Ying; Ramakrishnan, Hariharan; de Souza, Sabrina; Eller, Olivia C; Smoyer, Christine J; Baumbauer, Kyle M; Mack, Matthias; Folger, Joseph K; Robison, Alfred J; Linnstaedt, Sarah D; Laumet, Geoffroy	February 20, 2026	Not Determined
41321915	Create Study	Defining the r factor for post-trauma resilience and its neural predictors.	Nature. Mental health	van Rooij, Sanne J H; Santos, Justin L; Hinojosa, Cecilia A; Ely, Timothy D; Harnett, Nathaniel G; Murty, Vishnu P; Lebois, Lauren A M; Jovanovic, Tanja; House, Stacey L; Bruce, Steven E; Beaudoin, Francesca L; An, Xinming; Neylan, Thomas C; Clifford, Gari D; Linnstaedt, Sarah D; Germine, Laura T; Bollen, Kenneth A; Rauch, Scott L; Haran, John P; Storrow, Alan B; Lewandowski, Christopher; Musey Jr, Paul I; Hendry, Phyllis L; Sheikh, Sophia; Jones, Christopher W; Punches, Brittany E; Swor, Robert A; Pascual, Jose L; Seamon, Mark J; Harris, Erica; Pearson, Claire; Peak, David A; Merchant, Roland C; Domeier, Robert M; Rathlev, Niels K; O'Neil, Brian J; Sanchez, Leon D; Joormann, Jutta; Pizzagalli, Diego A; Sheridan, John F; Harte, Steven E; Kessler, Ronald C; Koenen, Karestan C; McLean, Samuel A; Ressler, Kerry J; Stevens, Jennifer S	June 1, 2024	Not Determined
41181354	Create Study	Brain dynamics reflecting an intra-network brain state is associated with increased posttraumatic stress symptoms in the early aftermath of trauma.	Nature. Mental health	Sendi, Mohammad Se; Fu, Zening; Harnett, Nathaniel G; van Rooij, Sanne J H; Vergara, Victor; Pizzagalli, Diego A; Daskalakis, Nikolaos P; House, Stacey L; Beaudoin, Francesca L; An, Xinming; Neylan, Thomas C; Clifford, Gari D; Jovanovic, Tanja; Linnstaedt, Sarah D; Germine, Laura T; Bollen, Kenneth A; Rauch, Scott L; Haran, John P; Storrow, Alan B; Lewandowski, Christopher; Musey Jr, Paul I; Hendry, Phyllis L; Sheikh, Sophia; Jones, Christopher W; Punches, Brittany E; Swor, Robert A; Gentile, Nina T; Murty, Vishnu P; Hudak, Lauren A; Pascual, Jose L; Seamon, Mark J; Harris, Erica; Chang, Anna M; Pearson, Claire; Peak, David A; Merchant, Roland C; Domeier, Robert M; Rathlev, Niels K; O'Neil, Brian J; Sergot, Paulina; Sanchez, Leon D; Bruce, Steven E; Sheridan, John F; Harte, Steven E; Kessler, Ronald C; Koenen, Karestan C; McLean, Samuel A; Stevens, Jennifer S; Calhoun, Vince D; Ressler, Kerry J	February 1, 2025	Not Determined
41136357	Create Study	Post-traumatic stress and genetic interactions affect tobacco and alcohol use after trauma: findings from a multi-ancestry cohort.	Translational psychiatry	Garrison-Desany, Henri M; Hinojosa, Cecilia A; Tubbs, Justin D; Meyers, Jacquelyn L; Linnstaedt, Sarah D; House, Stacey L; Beaudoin, Francesca L; An, Xinming; Stevens, Jennifer S; Neylan, Thomas C; Clifford, Gari D; Germine, Laura T; Rauch, Scott L; Haran, John P; Storrow, Alan B; Musey Jr, Paul I; Hendry, Phyllis L; Sheikh, Sophia; Jones, Christopher W; Punches, Brittany E; Pascual, Jose L; Seamon, Mark J; Harris, Erica; Pearson, Claire; Peak, David A; Merchant, Roland C; Domeier, Robert M; O'Neil, Brian J; Sergot, Paulina; Sanchez, Leon D; Bruce, Steven E; Harte, Steven E; McLean, Samuel A; Ressler, Kerry J; Koenen, Karestan C; Denckla, Christy A	October 24, 2025	Not Determined
40909772	Create Study	Comprehensive mapping of cognitive and emotion networks in stress, anxiety, and depression implicates the precuneus as a critical hub.	Research square	Sendi, Mohammad; Halko, Mark; Traynor, Jenna; Brown, Joshua; Copersino, Marc; Nickerson, Lisa; Harnett, Nathaniel; van Rooij, Sanne; Pizzagalli, Diego; House, Stacey; Beaudoin, Francesca; An, Xinming; Neylan, Thomas; Clifford, Gari; Jovanovic, Tanja; Linnstaedt, Sarah; Germine, Laura; Bollen, Kenneth; Rauch, Scott; Haran, John; Storrow, Alan; Lewandowski, Christopher; Musey Jr, Paul; Hendry, Phyllis; Sheikh, Sophia; Jones, Christopher; Punches, Brittany; Swor, Robert; Gentile, Nina; Hudak, Lauren; Pascual, Jose; Seamon, Mark; Harris, Erica; Pearson, Claire; Peak, David; Domeier, Robert; Rathlev, Niels; O'Neil, Brian; Sergot, Paulina; Sanchez, Leon; Bruce, Steven; Sheridan, John; Harte, Steven; Kessler, Ronald; Koenen, Karestan; Phelps, Elizabeth; Salat, David; Mayberg, Helen; McLean, Samuel; Stevens, Jennifer; Calhoun, Vince; Ressler, Kerry; Dillon, Daniel	August 26, 2025	Not Determined
40843243	Create Study	Emotion identification and emotion sensitivity following interpersonal and non-interpersonal traumatic experiences: Results from the AURORA study.	Clinical psychological science : a journal of the Association for Psychological Science	Hudson, Chloe C; Rutter, Lauren; Joormann, Jutta; Passell, Eliza; McKemey, Rory M; House, Stacey L; Beaudoin, Francesca L; An, Xinming; Stevens, Jennifer S; Neylan, Thomas C; Jovanovic, Tanja; Linnstaedt, Sarah D; Rauch, Scott L; Haran, John P; Storrow, Alan B; Lewandowski, Christopher; Musey Jr, Paul I; Hendry, Phyllis L; Sheikh, Sophia; Jones, Christopher W; Punches, Brittany E; Hudak, Lauren A; Pascual, Jose L; Seamon, Mark J; Datner, Elizabeth M; Pearson, Claire; Peak, David A; Merchant, Roland C; Domeier, Robert M; Rathlev, Niels K; O'Neil, Brian J; Sergot, Paulina; Sanchez, Leon D; Bruce, Steven E; Harte, Steven E; Kessler, Ronald C; Koenen, Karestan C; McLean, Samuel A; Germine, Laura T	August 16, 2025	Not Determined
40839592	Create Study	Early life adversity increases risk for chronic post-traumatic pain, data from humans and rodents.	Pain	McKibben, Lauren A; Woolard, Alice; McLean, Samuel A; Zhao, Ying; Verma, Taanvii; Mickelson, Jacqueline; Lu, Hongxia; Lobo, Jarred; House, Stacey L; Beaudoin, Francesca L; An, Xinming; Stevens, Jennifer S; Neylan, Thomas C; Jovanovic, Tanja; Germine, Laura T; Rauch, Scott L; Haran, John P; Storrow, Alan B; Lewandowski, Christopher; Hendry, Phyllis L; Sheikh, Sophia; Jones, Christopher W; Punches, Brittany E; Hudak, Lauren A; Pascual, Jose L; Seamon, Mark J; Pearson, Claire; Peak, David A; Merchant, Roland C; Domeier, Robert M; Rathlev, Niels K; O'Neil, Brian J; Sanchez, Leon D; Bruce, Steven E; Sheridan, John F; Kessler, Ronald C; Koenen, Karestan C; Ressler, Kerry J; Linnstaedt, Sarah D	June 18, 2025	Not Determined
40763107	Create Study	Association Between Acute Plasma Glial Fibrillary Acidic Protein Levels and White Matter Integrity in Recent Trauma Survivors.	Journal of neurotrauma	Huibregtse, Megan E; Li, Tianyi; Harnett, Nathaniel G; Yuh, Esther L; Ely, Timothy D; Jovanovic, Tanja; Calhoun, Vince D; Neylan, Thomas C; House, Stacey L; Clifford, Gari D; Bucher, Meredith A; Linnstaedt, Sarah D; An, Xinming; Conti, Alana C; Seligowski, Antonia V; Li, Qiao; Dillon, Daniel G; Vizer, Lisa M; McKibben, Lauren A; Albertorio-Sáez, Liz Marie; Beaudoin, Francesca L; Wang, Kevin K W; Matson, Liana; Harte, Steven E; Bruce, Steven E; Haran, John P; Storrow, Alan B; Lewandowski, Christopher; Musey Jr, Paul I; Hendry, Phyllis L; Jones, Christopher W; Swor, Robert A; Pearson, Claire; Peak, David A; O'Neil, Brian J; Kessler, Ronald C; Koenen, Karestan C; Ressler, Kerry J; McLean, Samuel A; Stevens, Jennifer S	October 1, 2025	Not Determined
40705576	Create Study	Predicting Traumatic Brain Injury Post-Trauma Using Temporal Attention on Sleep-Wake Data.	IEEE transactions on bio-medical engineering	Saghafi, Soheil; Li, Qiao; Neylan, Thomas C; T, Tommy Thomas; Stevens, Jennifer S; Jovanovic, Tanja; Germine, Laura T; Bucher, Meredith A; Huibregtse, Megan E; Linnstaedt, Sarah D; An, Xinming; Harnett, Nathaniel G; Norrholm, Seth D; Conti, Alana C; Seligowski, Antonia V; Dillon, Daniel G; Vizer, Lisa M; McKibben, Lauren A; Albertorio-Saez, Liz Marie; Beaudoin, Francesca L; Matson, Liana; Calhoun, Vince D; Harte, Steven E; Bruce, Steven E; Haran, John P; Storrow, Alan B; Lewandowski, Christopher; Musey, Paul I; Hendry, Phyllis L; Swor, Robert A; Pearson, Claire; Peak, David A; O'Neil, Brian J; Kessler, Ronald C; Koenen, Karestan C; McLean, Samuel A; Clifford, Gari D; Rad, Ali Bahrami	February 1, 2026	Not Determined
40582081	Create Study	Pre-trauma insomnia and posttraumatic alcohol and cannabis use in the AURORA observational cohort study of trauma survivors.	Journal of psychiatric research	Short, Nicole A; Ellis, Robyn A; Pezza, Mattea; House, Stacey L; Beaudoin, Francesca L; An, Xinming; Clifford, Gari D; Jovanovic, Tanja; Linnstaedt, Sarah D; Rauch, Scott L; Haran, John P; Storrow, Alan B; Lewandowski, Christopher; Musey, Paul I; Hendry, Phyllis L; Sheikh, Sophia; Jones, Christopher W; Punches, Brittany E; Hudak, Lauren A; Pascual, Jose L; Seamon, Mark J; Pearson, Claire; Peak, David A; Merchant, Roland C; Domeier, Robert M; Rathlev, Niels K; O'Neil, Brian J; Sanchez, Leon D; Bruce, Steven E; Harte, Steven E; Kessler, Ronald C; Koenen, Karestan C; Ressler, Kerry J; McLean, Samuel A; Neylan, Thomas C	September 1, 2025	Not Determined
40539444	Create Study	Early life adversity increases risk for chronic post-traumatic pain, data from humans and rodents.	Pain	McKibben, Lauren A; Woolard, Alice; McLean, Samuel A; Zhao, Ying; Verma, Taanvii; Mickelson, Jacqueline; Lu, Hongxia; Lobo, Jarred; House, Stacey L; Beaudoin, Francesca L; An, Xinming; Stevens, Jennifer S; Neylan, Thomas C; Jovanovic, Tanja; Germine, Laura T; Rauch, Scott L; Haran, John P; Storrow, Alan B; Lewandowski, Christopher; Hendry, Phyllis L; Sheikh, Sophia; Jones, Christopher W; Punches, Brittany E; Hudak, Lauren A; Pascual, Jose L; Seamon, Mark J; Pearson, Claire; Peak, David A; Merchant, Roland C; Domeier, Robert M; Rathlev, Niels K; O'Neil, Brian J; Sanchez, Leon D; Bruce, Steven E; Sheridan, John F; Kessler, Ronald C; Koenen, Karestan C; Ressler, Kerry J; Linnstaedt, Sarah D	June 18, 2025	Not Determined
40474763	Create Study	The reciprocal relationship between posttraumatic stress disorder symptoms and alcohol use in a large multisite longitudinal sample stratified by sex: A random-intercept cross-lagged panel model.	Alcohol, clinical & experimental research	Hinojosa, Cecilia A; van Rooij, Sanne J H; Fani, Negar; Ellis, Robyn A; Garrison-Desany, Henri M; House, Stacey L; Beaudoin, Francesca L; An, Xinming; Neylan, Thomas C; Clifford, Gari D; Linnstaedt, Sarah D; Germine, Laura T; Rauch, Scott L; AURORA Study Group; Koenen, Karestan C; Ressler, Kerry J; McLean, Samuel A; Stevens, Jennifer S	July 1, 2025	Not Determined
40406207	Create Study	Smartphone language features may help identify adverse post-traumatic neuropsychiatric sequelae and their trajectories.	NPP - digital psychiatry and neuroscience	Vizer, Lisa; Pierce, Jennifer; Ji, Yinyao; Bucher, Meredith A; Liu, Mochuan; Ungar, Lyle; Giorgi, Salvatore; Xing, Zhaopeng; House, Stacey L; Beaudoin, Francesca L; Stevens, Jennifer S; Neylan, Thomas C; Clifford, Gari D; Jovanovic, Tanja; Linnstaedt, Sarah D; Zeng, Donglin; Germine, Laura T; Bollen, Kenneth A; Rauch, Scott L; Haran, John P; Storrow, Alan B; Lewandowski, Christopher; Musey Jr, Paul I; Hendry, Phyllis L; Sheikh, Sophia; Jones, Christopher W; Punches, Brittany E; Hudak, Lauren A; Pascual, Jose L; Seamon, Mark J; Harris, Erica; Pearson, Claire; Peak, David A; Merchant, Roland C; Domeier, Robert M; O'Neil, Brian J; Sergot, Paulina; Sanchez, Leon D; Bruce, Steven E; Harte, Steven E; Kessler, Ronald C; Koenen, Karestan C; McLean, Samuel A; An, Xinming	January 1, 2025	Not Determined
40319171	Create Study	Sequential decreases in basolateral amygdala response to threat predict failure to recover from PTSD.	Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology	Roeckner, Alyssa R; Lin, Esther R-H; Hinrichs, Rebecca; Harnett, Nathaniel G; Lebois, Lauren A M; van Rooij, Sanne J H; Ely, Timothy D; Jovanovic, Tanja; Murty, Vishnu P; Bruce, Steven E; House, Stacey L; Beaudoin, Francesca L; An, Xinming; Neylan, Thomas C; Clifford, Gari D; Linnstaedt, Sarah D; Germine, Laura T; Rauch, Scott L; Haran, John P; Storrow, Alan B; Lewandowski, Christopher; Musey, Paul I; Hendry, Phyllis L; Sheikh, Sophia; Jones, Christopher W; Punches, Brittany E; Swor, Robert A; Hudak, Lauren A; Pascual, Jose L; Seamon, Mark J; Datner, Elizabeth M; Pearson, Claire; Peak, David A; Merchant, Roland C; Domeier, Robert M; Rathlev, Niels K; O'Neil, Brian J; Sergot, Paulina; Sanchez, Leon D; Joormann, Jutta; Sheridan, John F; Harte, Steven E; Koenen, Karestan C; Kessler, Ronald C; McLean, Samuel A; Ressler, Kerry J; Stevens, Jennifer S	September 1, 2025	Not Determined
40171069	Create Study	Understanding Onset, Dynamic Transitions, and Associated Inequality Risk Factors for Adverse Posttraumatic Neuropsychiatric Sequelae After Trauma Exposure.	Psychiatric research and clinical practice	Lee, Chiyoung; House, Stacey L; Beaudoin, Francesca L; Neylan, Thomas C; Clifford, Gari D; Linnstaedt, Sarah D; Germine, Laura T; Rauch, Scott L; Haran, John P; Storrow, Alan B; Lewandowski, Christopher; Musey Jr, Paul I; Hendry, Phyllis L; Sheikh, Sophia; Punches, Brittany E; Swor, Robert A; Hudak, Lauren A; Pascual, Jose L; Seamon, Mark J; Harris, Erica; Pearson, Claire; Peak, David A; Domeier, Robert M; Rathlev, Niels K; O'Neil, Brian J; Sergot, Paulina; Sanchez, Leon D; Bruce, Steven E; Sheridan, John F; Harte, Steven E; Koenen, Karestan C; Kessler, Ronald C; McLean, Samuel A; Yang, Qing; An, Xinming	January 1, 2025	Not Determined
40162284	Create Study	Childhood adversity is associated with longitudinal white matter changes after adulthood trauma.	medRxiv : the preprint server for health sciences	Tianyi, Li; Huibregtse, Megan E; Ely, Timothy D; van Rooij, Sanne J H; Lebois, Lauren A M; Webb, E Kate; Jovanovic, Tanja; House, Stacey L; Bruce, Steven E; Murty, Vishnu P; Beaudoin, Francesca L; An, Xinming; Neylan, Thomas C; Clifford, Gari D; Linnstaedt, Sarah D; Bollen, Kenneth A; Rauch, Scott L; Haran, John P; Storrow, Alan B; Lewandowski, Christopher; Musey Jr, Paul I; Hendry, Phyllis L; Sheikh, Sophia; Jones, Christopher W; Punches, Brittany E; Hudak, Lauren A; Pascual, Jose L; Seamon, Mark J; Datner, Elizabeth M; Pearson, Claire; Peak, David A; Merchant, Roland C; Domeier, Robert M; Rathlev, Niels K; O'Neil, Brian J; Sergot, Paulina; Sanchez, Leon D; Sheridan, John F; Kessler, Ronald C; Koenen, Karestan C; Ressler, Kerry J; McLean, Samuel A; Stevens, Jennifer S; Harnett, Nathaniel G	March 14, 2025	Not Determined
40119846	Create Study	Longitudinal Associations Between Peritraumatic Oestradiol and Fear Responding in Women and Men.	Stress and health : journal of the International Society for the Investigation of Stress	Ellis, Robyn A; Webber, Theresa K; Noble, Natalie C; Linnstaedt, Sarah D; Hinrichs, Rebecca; Wiltshire, Charis; Reda, Mariam H; Davie, William; House, Stacey L; Beaudoin, Francesca L; An, Xinming; Neylan, Thomas C; Clifford, Gari D; Germine, Laura T; Rauch, Scott L; Haran, John P; Storrow, Alan B; Lewandowski, Christopher; Musey Jr, Paul I; Hendry, Phyllis L; Sheikh, Sophia; Punches, Brittany E; Pascual, Jose L; Seamon, Mark J; Datner, Elizabeth M; Pearson, Claire; Peak, David A; Domeier, Robert M; Rathlev, Niels K; O'Neil, Brian J; Sergot, Paulina; Sanchez, Leon D; Bruce, Steven E; Joormann, Jutta; Kessler, Ronald C; Ressler, Kerry J; Koenen, Karestan C; McLean, Samuel A; Stevens, Jennifer S; Jovanovic, Tanja; Seligowski, Antonia V	April 1, 2025	Not Determined
40034773	Create Study	Associations between residential segregation, ambient air pollution, and hippocampal features in recent trauma survivors.	medRxiv : the preprint server for health sciences	Liang, Sophia S; Roeckner, Alyssa R; Ely, Timothy D; Lebois, Lauren A M; van Rooij, Sanne J H; Bruce, Steven E; Jovanovic, Tanja; House, Stacey L; Beaudoin, Francesca L; An, Xinming; Neylan, Thomas C; Clifford, Gari D; Linnstaedt, Sarah D; Germine, Laura T; Rauch, Scott L; Haran, John P; Storrow, Alan B; Lewandowski, Christopher; Musey Jr, Paul I; Hendry, Phyllis L; Sheikh, Sophia; Pascual, Jose L; Seamon, Mark J; Harris, Erica; Pearson, Claire; Peak, David A; Merchant, Roland C; Domeier, Robert M; Rathlev, Niels K; O'Neil, Brian J; Sergot, Paulina; Sanchez, Leon D; Sheridan, John F; Harte, Steven E; Kessler, Ronald C; Koenen, Karestan C; McLean, Samuel A; Ressler, Kerry J; Stevens, Jennifer S; Webb, E Kate; Harnett, Nathaniel G	February 20, 2025	Not Determined
40030431	Create Study	Continuous-Time Hidden Markov Factor Model for Mobile Health Data: Application to Adverse Posttraumatic Neuropsychiatric Sequelae.	IEEE journal of biomedical and health informatics	Ge, Lin; An, Xinming; Zeng, Donglin; McLean, Samuel; Kessler, Ronald; Song, Rui	February 1, 2025	Not Determined
39918603	Create Study	Multi-level socioeconomic modifiers of the comorbidity of post-traumatic stress and tobacco, alcohol, and cannabis use: the importance of income.	Social psychiatry and psychiatric epidemiology	Garrison-Desany, Henri M; Meyers, Jacquelyn L; Linnstaedt, Sarah D; Koenen, Karestan C; House, Stacey L; Beaudoin, Francesca L; An, Xinming; Neylan, Thomas C; Clifford, Gari D; Jovanovic, Tanja; Germine, Laura T; Bollen, Kenneth A; Rauch, Scott L; Haran, John P; Storrow, Alan B; Lewandowski, Christopher; Musey Jr, Paul I; Hendry, Phyllis L; Sheikh, Sophia; Jones, Christopher W; Punches, Brittany E; Pascual, Jose L; Seamon, Mark J; Harris, Erica; Pearson, Claire; Peak, David A; Domeier, Robert M; Rathlev, Niels K; O'Neil, Brian J; Sergot, Paulina; Bruce, Steven E; McLean, Samuel A; Denckla, Christy A	May 1, 2025	Not Determined
39696436	Create Study	Epigenome-wide association studies identify novel DNA methylation sites associated with PTSD: a meta-analysis of 23 military and civilian cohorts.	Genome medicine	Katrinli, Seyma; Wani, Agaz H; Maihofer, Adam X; Ratanatharathorn, Andrew; Daskalakis, Nikolaos P; Montalvo-Ortiz, Janitza; Núñez-Ríos, Diana L; Zannas, Anthony S; Zhao, Xiang; Aiello, Allison E; Ashley-Koch, Allison E; Avetyan, Diana; Baker, Dewleen G; Beckham, Jean C; Boks, Marco P; Brick, Leslie A; Bromet, Evelyn; Champagne, Frances A; Chen, Chia-Yen; Dalvie, Shareefa; Dennis, Michelle F; Fatumo, Segun; Fortier, Catherine; Galea, Sandro; Garrett, Melanie E; Geuze, Elbert; Grant, Gerald; Hauser, Michael A; Hayes, Jasmeet P; Hemmings, Sian M J; Huber, Bertrand Russel; Jajoo, Aarti; Jansen, Stefan; Kessler, Ronald C; Kimbrel, Nathan A; King, Anthony P; Kleinman, Joel E; Koen, Nastassja; Koenen, Karestan C; Kuan, Pei-Fen; Liberzon, Israel; Linnstaedt, Sarah D; Lori, Adriana; Luft, Benjamin J; Luykx, Jurjen J; Marx, Christine E; McLean, Samuel A; Mehta, Divya; Milberg, William; Miller, Mark W; Mufford, Mary S; Musanabaganwa, Clarisse; Mutabaruka, Jean; Mutesa, Leon; Nemeroff, Charles B; Nugent, Nicole R; Orcutt, Holly K; Qin, Xue-Jun; Rauch, Sheila A M; Ressler, Kerry J; Risbrough, Victoria B; Rutembesa, Eugène; Rutten, Bart P F; Seedat, Soraya; Stein, Dan J; Stein, Murray B; Toikumo, Sylvanus; Ursano, Robert J; Uwineza, Annette; Verfaellie, Mieke H; Vermetten, Eric; Vinkers, Christiaan H; Ware, Erin B; Wildman, Derek E; Wolf, Erika J; Young, Ross McD; Zhao, Ying; van den Heuvel, Leigh L; PGC-PTSD Epigenetics Workgroup; PsychENCODE PTSD Brainomics Project; Traumatic Stress Brain Research Group; Uddin, Monica; Nievergelt, Caroline M; Smith, Alicia K; Logue, Mark W	December 18, 2024	Not Determined
39677432	Create Study	Peritraumatic C-reactive protein levels predict pain outcomes following traumatic stress exposure in a sex-dependent manner.	medRxiv : the preprint server for health sciences	McKibben, Lauren A; Layne, Miranda N; Albertorio-Sáez, Liz Marie; Zhao, Ying; Branham, Erica M; House, Stacey L; Beaudoin, Francesca L; An, Xinming; Stevens, Jennifer S; Neylan, Thomas C; Clifford, Gari D; Germine, Laura T; Bollen, Kenneth A; Rauch, Scott L; Haran, John P; Storrow, Alan B; Lewandowski, Christopher; Musey Jr, Paul I; Hendry, Phyllis L; Sheikh, Sophia; Jones, Christopher W; Punches, Brittany E; Swor, Robert A; Hudak, Lauren A; Pascual, Jose L; Seamon, Mark J; Datner, Elizabeth M; Peak, David A; Merchant, Roland C; Domeier, Robert M; Rathlev, Niels K; O'Neil, Brian J; Sanchez, Leon D; Bruce, Steven E; Sheridan, John F; Harte, Steven E; Kessler, Ronald C; Koenen, Karestan C; Ressler, Kerry J; McLean, Samuel A; Linnstaedt, Sarah D	December 7, 2024	Not Determined
39603414	Create Study	Social Buffering of Posttraumatic Stress Disorder: Longitudinal Effects and Neural Mediators.	Biological psychiatry. Cognitive neuroscience and neuroimaging	Santos, Justin L C; Harnett, Nathaniel G; van Rooij, Sanne J H; Ely, Timothy D; Jovanovic, Tanja; Lebois, Lauren A M; Beaudoin, Francesca L; An, Xinming; Neylan, Thomas C; Linnstaedt, Sarah D; Germine, Laura T; Bollen, Kenneth A; Rauch, Scott L; Haran, John P; Storrow, Alan B; Lewandowski, Christopher; Musey Jr, Paul I; Hendry, Phyllis L; Sheikh, Sophia; Jones, Christopher W; Punches, Brittany E; Pascual, Jose L; Seamon, Mark J; Harris, Erica; Pearson, Claire; Peak, David A; Merchant, Roland C; Domeier, Robert M; Rathlev, Niels K; O'Neil, Brian J; Sergot, Paulina; Sanchez, Leon D; Bruce, Steven E; Pizzagalli, Diego A; Harte, Steven E; Ressler, Kerry J; Koenen, Karestan C; McLean, Samuel A; Stevens, Jennifer S	May 1, 2025	Not Determined
39549594	Create Study	Heart rate variability wrist-wearable biomarkers identify adverse posttraumatic neuropsychiatric sequelae after traumatic stress exposure.	Psychiatry research	Guichard, Lauriane; An, Xinming; Neylan, Thomas C; Clifford, Gari D; Li, Qiao; Ji, Yinyao; Macchio, Lindsay; Baker, Justin; Beaudoin, Francesca L; Jovanovic, Tanja; Linnstaedt, Sarah D; Germine, Laura T; Bollen, Kenneth A; Rauch, Scott L; Haran, John P; Storrow, Alan B; Lewandowski, Christopher; Musey Jr, Paul I; Hendry, Phyllis L; Sheikh, Sophia; Jones, Christopher W; Punches, Brittany E; Swor, Robert A; Gentile, Nina T; Pascual, Jose L; Seamon, Mark J; Datner, Elizabeth M; Pearson, Claire; Peak, David A; Merchant, Roland C; Domeier, Robert M; Rathlev, Niels K; O'Neil, Brian J; Sergot, Paulina; Sanchez, Leon D; Bruce, Steven E; Sheridan, John F; Harte, Steven E; Ressler, Kerry J; Koenen, Karestan C; Kessler, Ronald C; McLean, Samuel A; AURORA Study Group	December 1, 2024	Not Determined
39534178	Create Study	Disentangling sex differences in PTSD risk factors.	Nature. Mental health	Haering, Stephanie; Seligowski, Antonia V; Linnstaedt, Sarah D; Michopoulos, Vasiliki; House, Stacey L; Beaudoin, Francesca L; An, Xinming; Neylan, Thomas C; Clifford, Gari D; Germine, Laura T; Rauch, Scott L; Haran, John P; Storrow, Alan B; Lewandowski, Christopher; Musey Jr, Paul I; Hendry, Phyllis L; Sheikh, Sophia; Jones, Christopher W; Punches, Brittany E; Swor, Robert A; Gentile, Nina T; Hudak, Lauren A; Pascual, Jose L; Seamon, Mark J; Pearson, Claire; Peak, David A; Merchant, Roland C; Domeier, Robert M; Rathlev, Niels K; O'Neil, Brian J; Sanchez, Leon D; Bruce, Steven E; Harte, Steven E; McLean, Samuel A; Kessler, Ronald C; Koenen, Karestan C; Powers, Abigail; Stevens, Jennifer S	May 1, 2024	Not Determined

helpcenter.collection.publications-tab

Collection - Publications

The number of Publications is displayed in parentheses next to the tab name. Clicking on any of the Publication Titles will open the Publication in a new internet browsing tab.

Collection Owners, Program Officers, and users with Submission or Administrative Privileges for the Collection may mark a publication as either Relevant or Not Relevant in the Status column.

Frequently Asked Questions

How can I determine if a publication is relevant?

Publications are considered relevant to a collection when the data shared is directly related to the project or collection.
Where does the NDA get the publications?

PubMed, an online library containing journals, articles, and medical research. Sponsored by NiH and National Library of Medicine (NLM).

Glossary

Create Study

A link to the Create an NDA Study page that can be clicked to start creating an NDA Study with information such as the title, journal and authors automatically populated.
Not Determined Publication

Indicates that the publication has not yet been reviewed and/or marked as Relevant or Not Relevant so it has not been determined whether an NDA Study is expected.
Not Relevant Publication

A publication that is not based on data related to the aims of the grant/project associated with the Collection or not based on any data such as a review article and, therefore, an NDA Study is not expected to be created.
PubMed

PubMed provides citation information for biomedical and life sciences publications and is managed by the U.S. National Institutes of Health's National Library of Medicine.
PubMed ID

The PUBMed ID is the unique ID number for the publication as recorded in the PubMed database.
Relevant Publication

A publication that is based on data related to the aims of the grant/project associated with the Collection and, therefore, an NDA Study is expected to be created.

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Data Expected List: Mandatory Data Structures

These data structures are mandatory for your NDA Collection. Please update the Targeted Enrollment number to accurately represent the number of subjects you expect to submit for the entire study.

For NIMH HIV-related research that involves human research participants: Select the dictionary or dictionaries most appropriate for your research. If your research does not require all three data dictionaries, just ignore the ones you do not need. There is no need to delete extra data dictionaries from your NDA Collection. You can adjust the Targeted Enrollment column in the Data Expected tab to “0” for those unnecessary data dictionaries. At least one of the three data dictionaries must have a non-zero value.

Data Expected	Targeted Enrollment	Initial Submission	Subjects Submitted	Initial Share	Subjects Shared	Status
Genomics/omics	4,000	01/17/2023	2,747	03/17/2023	2,741	Approved
Research Subject and Pedigree	5,000	01/15/2020	3,828	05/15/2020	3,828	Approved

To create your project's Data Expected list, use the "+New Data Expected" to add or request existing structures and to request new Data Structures that are not in the NDA Data Dictionary.

If the Structure you need already exists, locate it and specify your dates and enrollment when adding it to your Data Expected list. If you require changes to the Structure you need, select the indicator stating "No, it requires changes to meet research needs," and upload a file containing your requested changes.

If the structure you need is not yet defined in the Data Dictionary, you can select "Upload Definition" and attach the necessary materials to request its creation.

When selecting the expected dates for your data, make sure to follow the standard Data Sharing Regimen and choose dates within the date ranges that correspond to your project start and end dates.

Please visit the Completing Your Data Expected Tutorial for more information.

Data Expected List: Data Structures per Research Aims

These data structures are specific to your research aims and should list all data structures in which data will be collected and submitted for this NDA Collection. Please update the Targeted Enrollment number to accurately represent the number of subjects you expect to submit for the entire study.

Data Expected	Targeted Enrollment	Initial Submission	Subjects Submitted	Initial Share	Subjects Shared	Status
Life Events Checklist	5,000	02/28/2019	2,635	05/15/2019	2,635	Approved
Perceived Stress Scale	5,000	07/15/2018	3,827	11/15/2019	3,827	Approved
Penn Emotion Recognition Task-40	5,000	07/15/2018	2,527	11/15/2019	2,527	Approved
Childhood Trauma Questionnaire	5,000	07/15/2018	3,160	05/15/2019	2,899	Approved
Medical History	5,000	07/15/2018	3,804	05/15/2019	3,804	Approved
Demographics	5,000	07/15/2018	3,827	05/15/2019	3,827	Approved
Vital Signs Assessment	5,000	07/15/2018	3,797	05/15/2019	3,797	Approved
Big Five Inventory	5,000	07/15/2018	3,160	05/15/2019	3,160	Approved
Medications	5,000	07/15/2018	3,106	11/15/2019	3,106	Approved
Substance Use Survey	5,000	07/15/2018	3,827	11/15/2019	3,827	Approved
Pittsburgh Sleep Quality Index	5,000	07/15/2018	3,827	11/15/2019	3,827	Approved
Screening Form	5,000	07/15/2018	3,827	05/15/2019	3,827	Approved
The Life Events Checklist for DSM-5	4,000	05/01/2023	2,943	11/02/2023	0	Approved
PTSD Checklist - Civilian	5,000	07/15/2018	3,827	11/15/2019	3,827	Approved
Sheehan Disability Scale	5,000	07/15/2018	3,827	11/15/2019	3,827	Approved
Drug Screen	5,000	07/15/2018	3,797	11/15/2019	3,797	Approved
Imaging (Structural, fMRI, DTI, PET, microscopy)	800	02/28/2019	499	11/15/2019	424	Approved
Anxiety Sensitivity Index	5,000	07/15/2018	3,160	05/15/2019	2,899	Approved
Startle Testing Summary	800	07/15/2018	543	05/15/2019	543	Approved
Probabilistic Reward Task	5,000	07/15/2018	593	11/15/2019	593	Approved
UPPS Impulsive Behavior Scale	5,000	07/15/2018	3,184	11/15/2019	3,184	Approved
Peritraumatic Distress Inventory	5,000	07/15/2018	3,827	11/15/2019	3,827	Approved
Emotional Distress-Anxiety	5,000	07/15/2018	3,827	11/15/2019	3,827	Approved
Emotional Distress - Depression	5,000	07/15/2018	3,828	11/15/2019	3,828	Approved
Digit Symbol Substitution Test	5,000	07/15/2018	2,672	11/15/2019	2,672	Approved
Short Form Health Survey	5,000	07/15/2018	3,827	11/15/2019	3,827	Approved
Connor Davidson Resiliency Scale	5,000	07/15/2018	3,184	11/15/2019	3,099	Approved
Delay Discounting Task	5,000	07/15/2018	669	11/15/2019	669	Approved
Berlin Apnea Questionnaire	5,000	07/15/2018	3,160	05/15/2019	2,899	Approved
Composite International Diagnostic Interview	5,000	07/15/2018	3,827	11/15/2019	3,827	Approved
Dot Probe Task	5,000	07/15/2018	1,578	11/15/2019	1,578	Approved
Adult ADHD Self-Report Scale	5,000	07/15/2018	3,184	11/15/2019	3,184	Approved
Traumatic Brain Injury	5,000	07/15/2018	3,827	05/15/2019	3,827	Approved
Reaction Time Task	5,000	07/15/2018	854	11/15/2019	854	Approved
Go-No Go Variant Task	5,000	01/15/2019	2,955	11/15/2019	2,583	Approved
Insomnia Severity Index	5,000	07/15/2018	3,827	11/15/2019	3,827	Approved
Electro-dermal Activity	5,000	01/15/2019	3,572	05/15/2019	1,375	Approved
Sleep-Related Impairment	5,000	01/15/2020	3,840	05/15/2020	3,840	Approved
Wearable Data	5,000	07/15/2018	0	11/15/2019	0	Approved
Task Based	5,000	07/15/2018	0	11/15/2019	0	Approved
Emergency Room Diagnosis	5,000	07/15/2018	3,797	05/15/2019	3,797	Approved
Circadian Energy Scale	5,000	07/15/2018	3,160	05/15/2019	2,899	Approved
Car Crash Assessment	5,000	07/15/2018	3,827	05/15/2019	3,827	Approved
Belmont Emotion Sensitivity Test	5,000	02/28/2020	1,261	08/28/2020	1,261	Approved
PROMIS Support	5,000	07/15/2018	3,184	11/15/2019	3,184	Approved
List of Threatening Experiences Questionnaire	5,000	02/28/2019	2,971	11/15/2019	2,971	Approved
Pain Survey	5,000	07/15/2018	3,827	11/15/2019	3,827	Approved
Attitudes Towards Risk	5,000	07/15/2018	3,184	11/15/2019	3,184	Approved
Perception of Severity of Stress	5,000	07/15/2018	3,827	11/15/2019	3,827	Approved
Verbal Paired Associates Memory	5,000	07/15/2018	2,520	11/15/2019	2,520	Approved
AURORA_FLASH_COVID	5,000	08/28/2020	1,152	12/28/2020	0	Approved
Clinician Administered PTSD Severity Scale	5,000	07/15/2018	3,827	11/15/2019	3,827	Approved
Rumination-Reflection Questionnaire	5,000	07/15/2018	3,827	11/15/2019	3,827	Approved
Emergency Room Chief Complaint	5,000	07/15/2018	3,797	05/15/2019	3,797	Approved
Pain Tasks	800	01/15/2019	574	11/15/2019	559	Approved
Military Service Questionnaire	984	07/15/2018	2,899	05/15/2019	2,899	Approved
Cognitive Bias Test	5,000	02/28/2020	1,267	08/28/2020	1,267	Approved
AURORA Flash Survey Latent Construct Anxiety	3,827	02/14/2023	2,543	08/14/2023	0	Approved
AURORA Flash Survey Latent Construct Arousal	3,827	02/08/2023	2,554	08/08/2023	0	Approved
AURORA Flash Survey Latent Construct Avoidance	3,827	02/08/2023	2,552	08/08/2023	0	Approved
AURORA Flash Survey Latent Construct Fatigue	3,827	02/14/2023	2,554	08/14/2023	0	Approved
AURORA Flash Survey Latent Construct Loss	3,827	02/08/2023	2,543	08/08/2023	0	Approved
Religiosity Form	984	07/15/2018	3,160	05/15/2019	3,160	Approved
Threat Neutral Sternberg	5,000	07/15/2018	1,486	11/15/2019	1,486	Approved
Vocabulary Series	5,000	07/15/2018	743	11/15/2019	743	Approved
Ten Item Personality Measure	5,000	07/15/2018	3,160	05/15/2019	3,160	Approved
Pennebaker Inventory of Limbic Languidness	5,000	07/15/2018	3,827	11/15/2019	3,827	Approved
Health Service Utilization	5,000	07/15/2018	3,000	11/15/2019	3,000	Approved
Forward Digit Span	5,000	07/15/2018	2,510	11/15/2019	2,510	Approved
Dissociative Experiences Scale	5,000	07/15/2018	3,827	11/15/2019	3,827	Approved
Five Facet Mindfulness Questionnaire	5,000	07/15/2018	3,184	11/15/2019	3,099	Approved
Emergency Room Radiology	5,000	07/15/2018	3,797	05/15/2019	3,797	Approved
PROMIS Self-Efficacy for Managing Emotions	5,000	07/15/2018	3,160	05/15/2019	2,899	Approved
Deep Phenotyping Session	800	02/28/2020	0	08/28/2020	0	Approved
Emergency Room Injuries Assessment	5,000	07/15/2018	3,798	05/15/2019	3,797	Approved
Emergency Room Trauma Assessment	5,000	07/15/2018	3,827	05/15/2019	3,827	Approved
Exit Form	5,000	07/15/2018	3,827	11/15/2019	3,827	Approved
Mindstrong Flash Survey	5,000	07/15/2018	3,555	11/15/2019	3,370	Approved
NCA_cRT_Raw_001	5,000	01/15/2020	2,948	05/15/2020	2,948	Approved
Implicit Association Test	5,000	02/28/2020	1,265	08/28/2020	1,265	Approved
Polygenic Risk Scores	4,000	11/30/2022	1,005	12/30/2022	1,005	Approved
Michigan Critical Events Perception Scale	5,000	07/15/2018	3,827	05/15/2019	3,827	Approved
Emergency Room Medications	1,090	07/15/2018	3,799	05/15/2019	3,799	Approved
AURORA_Flash_Discrimination	2,000	07/31/2021	428	12/28/2021	0	Approved
AURORA Smartwatch PPG Products	4,000	05/03/2023	3,412	11/03/2023	0	Approved
AURORA Flash Survey Latent Construct Multi-Dimensional	3,827	02/28/2023	2,349	08/28/2023	0	Approved
Survey General Indicator Scores	4,000	03/23/2023	2,943	09/23/2023	0	Approved
AURORA Neurocognitive Assessment Choice Reaction Time	4,000	04/14/2023	2,784	10/14/2023	0	Approved
AURORA Neurocognitive Assessment Delay Discounting	4,000	04/17/2023	2,268	10/17/2023	0	Approved
AURORA Neurocognitive Assessment Forward Digits	4,000	03/17/2023	2,814	09/17/2023	0	Approved
AURORA Neurocognitive Assessment Gradual Continuous Performance Test	4,000	04/14/2023	2,738	10/14/2023	0	Approved
AURORA Neurocognitive Assessment Vocabulary and Verbal Association	4,000	04/11/2023	974	10/11/2023	974	Approved
AURORA Flash Survey Latent Construct Sleep	3,827	03/01/2023	2,547	09/01/2023	0	Approved
AURORA Flash Survey Latent Construct Re-Experience	3,827	02/02/2023	2,552	08/20/2023	0	Approved
AURORA Watch Activity Timeseries	4,000	04/11/2023	3,410	10/11/2023	0	Approved
AURORA Neurocognitive Assessment Digit Symbol	4,000	03/17/2023	2,807	09/17/2023	0	Approved
AURORA Neurocognitive Assessment Implicit Association Test	4,000	04/14/2023	1,574	10/14/2023	0	Approved
AURORA Neurocognitive Assessment Sternberg	4,000	04/14/2023	1,615	10/14/2023	0	Approved
AURORA eSense Product	4,000	04/21/2023	1,181	10/21/2023	0	Approved
AURORA Neurocognitive Assessment Probabilistic Reward	4,000	06/09/2023	841	10/09/2023	0	Approved
AURORA Flash Survey Latent Construct Pain	3,827	02/20/2023	2,410	08/20/2023	0	Approved
AURORA Keystroke Biomarker	4,000	05/10/2023	22	06/10/2023	22	Approved
AURORA Watch Sleep	4,000	04/11/2023	3,389	10/11/2023	0	Approved
AURORA Neurocognitive Assessment Cognitive Bias	4,000	04/14/2023	1,576	10/14/2023	0	Approved
AURORA Startle Scored	4,000	04/14/2023	542	10/14/2023	0	Approved
AURORA Latent Construct Negative Affect Survey	4,000	03/13/2023	2,626	09/13/2023	0	Approved
AURORA Latent Construct Sleep Discontinuity Survey	4,000	03/13/2023	2,626	09/13/2023	0	Approved
AURORA Latent Construct Fatigue Survey	3,827	03/03/2023	2,626	09/20/2023	0	Approved
AURORA Latent Construct Anhedonia Survey	3,827	03/03/2023	2,626	09/03/2023	0	Approved
AURORA Watch Activity Counts	4,000	03/23/2023	153	09/23/2023	153	Approved
AURORA Sentiment Biomarker	4,000	04/21/2023	2,644	10/21/2023	0	Approved
Aurora Verily	5,000	07/15/2018	0	05/15/2019	0	Approved
AURORA Flash Survey Latent Construct Somatic	3,827	03/06/2023	2,554	09/03/2023	0	Approved
AURORA Latent Construct Nightmare Survey	4,000	03/13/2023	2,626	09/13/2023	0	Approved
AURORA Latent Construct Threat Survey	4,000	06/09/2023	2,626	10/09/2023	0	Approved
AURORA Neurocognitive Assessment Dot Probe	4,000	03/17/2023	1,625	09/17/2023	0	Approved
AURORA Neurocognitive Assessment Emotion Recognition	4,000	07/14/2023	2,744	10/14/2023	2,744	Approved
AURORA Neurocognitive Assessment Standard Reaction Time	4,000	03/17/2023	2,823	09/17/2023	0	Approved
AURORA Flash Survey Latent Construct Nightmare	3,827	02/28/2023	2,547	08/28/2023	0	Approved
AURORA Communication Biomarker	4,000	03/23/2023	680	09/23/2023	0	Approved
AURORA Positional Biomarker	4,000	03/23/2023	1,035	09/23/2023	0	Approved

Structure not yet defined

No Status history for this Data Expected has been recorded yet

helpcenter.collection.data-expected-tab

Collection - Data Expected

The Data Expected tab displays the list of all data that NDA expects to receive in association with the Collection as defined by the contributing researcher, as well as the dates for the expected initial upload of the data, and when it is first expected to be shared, or with the research community. Above the primary table of Data Expected, any publications determined to be relevant to the data within the Collection are also displayed - members of the contributing research group can use these to define NDA Studies, connecting those papers to underlying data in NDA.

The tab is used both as a reference for those accessing shared data, providing information on what is expected and when it will be shared, and as the primary tracking mechanism for contributing projects. It is used by both contributing primary researchers, secondary researchers, and NIH Program and Grants Management staff.

Researchers who are starting their project need to update their Data Expected list to include all the Data Structures they are collecting under their grant and set their initial submission and sharing schedule according to the NDA Data Sharing Regimen.

To add existing Data Structures from the Data Dictionary, to request new Data Structure that are not in the Dictionary, or to request changes to existing Data Structures, click "+New Data Expected".

For step-by-step instructions on how to add existing Data Structures, request changes to an existing Structure, or request a new Data Structure, please visit the Completing Your Data Expected Tutorial.

If you are a contributing researcher creating this list for the first time, or making changes to the list as your project progress, please note the following:

Although items you add to the list and changes you make are displayed, they are not committed to the system until you Save the entire page using the "Save" button at the bottom of your screen. Please Save after every change to ensure none of your work is lost.
If you attempt to add a new structure, the title you provide must be unique - if another structure exists with the same name your change will fail.
Adding a new structure to this list is the only way to request the creation of a new Data Dictionary definition.

Frequently Asked Questions

What is an NDA Data Structure?

An NDA Data Structure is comprised of multiple Data Elements to make up an electronic definition of an assessment, measure, questionnaire, etc will have a corresponding Data Structure.
What is the NDA Data Dictionary?

The NDA Data Dictionary is comprised of electronic definitions known as Data Structures.

Glossary

Analyzed Data

Data specific to the primary aims of the research being conducted (e.g. outcome measures, other dependent variables, observations, laboratory results, analyzed images, volumetric data, etc.) including processed images.
Data Item

Items listed on the Data Expected list in the Collection which may be an individual and discrete Data Structure, Data Structure Category, or Data Structure Group.
Data Structure

A defined organization and group of Data Elements to represent an electronic definition of a measure, assessment, questionnaire, or collection of data points. Data structures that have been defined in the NDA Data Dictionary are available at https://nda.nih.gov/general-query.html?q=query=data-structure
Data Structure Category

An NDA term describing the affiliation of a Data Structure to a Category, which may be disease/disorder or diagnosis related (Depression, ADHD, Psychosis), specific to data type (MRI, eye tracking, omics), or type of data (physical exam, IQ).
Data Structure Group

A Data Item listed on the Data Expected tab of a Collection that indicates a group of Data Structures (e.g., ADOS or SCID) for which data may be submitted instead of a specific Data Structure identified by version, module, edition, etc. For example, the ADOS Data Structure Category includes every ADOS Data Structure such as ADOS Module 1, ADOS Module 2, ADOS Module 1 - 2nd Edition, etc. The SCID Data Structure Group includes every SCID Data Structure such as SCID Mania, SCID V Mania, SCID PTSD, SCID-V Diagnosis, and more.
Evaluated Data

A new Data Structure category, Evaluated Data is analyzed data resulting from the use of computational pipelines in the Cloud and can be uploaded directly back to a miNDAR database. Evaluated Data is expected to be listed as a Data Item in the Collection's Data Expected Tab.
Imaging Data

Imaging+ is an NDA term which encompasses all imaging related data including, but not limited to, images (DTI, MRI, PET, Structural, Spectroscopy, etc.) as well as neurosignal data (EEG, fMRI, MEG, EGG, eye tracking, etc.) and Evaluated Data.
Initial Share Date

Initial Submission and Initial Share dates should be populated according to the NDA Data Sharing Terms and Conditions. Any modifications to these will go through the approval processes outlined above. Data will be shared with authorized users upon publication (via an NDA Study) or 1-2 years after the grant end date specified on the first Notice of Award, as defined in the applicable Data Sharing Terms and Conditions.
Initial Submission Date

Initial Submission and Initial Share dates should be populated according to these NDA Data Sharing Terms and Conditions. Any modifications to these will go through the approval processes outlined above. Data for all subjects is not expected on the Initial Submission Date and modifications may be made as necessary based on the project's conduct.
Research Subject and Pedigree

An NDA created Data Structure used to convey basic information about the subject such as demographics, pedigree (links family GUIDs), diagnosis/phenotype, and sample location that are critical to allow for easier querying of shared data.
Submission Cycle

The NDA has two Submission Cycles per year - January 15 and July 15.
Submission Exemption

An interface to notify NDA that data may not be submitted during the upcoming/current submission cycle.

Contact NDA Help Desk

Collection Owners and those with Collection Administrator permission, may edit a collection. The following is currently available for Edit on this page:

Associated Studies

Studies that have been defined using data from a Collection are important criteria to determine the value of data shared. The number of subjects column displays the counts from this Collection that are included in a Study, out of the total number of subjects in that study. The Data Use column represents whether or not the study is a primary analysis of the data or a secondary analysis. State indicates whether the study is private or shared with the research community.

Study NameFilter by Study Name	DOIFilter by DOI	AbstractFilter by Abstract	Collection/Study SubjectsFilter by Collection/Study Subjects	Data UsageFilter by Data Usage	StateFilter by State
Disentangling sex differences in PTSD risk factors	10.15154/c01s-jy79	Despite decades of research on sex differences in posttraumatic stress disorder (PTSD), underlying mechanisms are still not fully understood. Here we present a systematic overview of three sex-related risk pathways. We assessed 16 risk factors as well as 3-month PTSD severity in a prospective cohort (n=2924) of acutely traumatized individuals and investigated potential mediators in the pathway between sex and PTSD using multiple mediation analysis with regularization. Six risk factors were more prevalent/severe in women, none was more pronounced in men. Analyses showed that acute stress disorder, neuroticism, anxiety sensitivity, peritraumatic distress and pre-trauma anxiety symptoms fully mediated and uniquely contributed to the relationship between sex and PTSD. Our results demonstrate different risk mechanisms for women and men. Such knowledge can inform targeted interventions to improve trauma outcomes. Our systematic approach to differential pathways for risk contribution can be transferred to other mental disorders to guide sex-sensitive mental health research.	3827/3827	Primary Analysis	Shared
Sex-dependent differences in vulnerability to early risk factors for posttraumatic stress disorder: Results from the AURORA study	10.15154/qfkt-cg42	Background: Knowledge of sex differences in risk factors for posttraumatic stress disorder (PTSD) can contribute to the development of refined preventive interventions. Therefore, the aim of this study was to examine if women and men differ in their vulnerability to risk factors for PTSD. Methods: As part of the longitudinal AURORA study, 2924 patients seeking emergency department (ED) treatment in the acute aftermath of trauma provided self-report assessments of pre- peri- and post-traumatic risk factors, as well as 3-month PTSD severity. We systematically examined sex-dependent effects of 16 risk factors that have previously been hypothesized to show different associations with PTSD severity in women and men. Results: Women reported higher PTSD severity at 3-months post-trauma. Z-score comparisons indicated that for five of the 16 examined risk factors the association with 3-month PTSD severity was stronger in men than in women. In multivariable models, interaction effects with sex were observed for pre-traumatic anxiety symptoms, and acute dissociative symptoms; both showed stronger associations with PTSD in men than in women. Subgroup analyses suggested trauma type-conditional effects. Conclusions: Our findings indicate mechanisms to which men might be particularly vulnerable, demonstrating that known PTSD risk factors might behave differently in women and men. Analyses did not identify any risk factors to which women were more vulnerable than men, pointing toward further mechanisms to explain women's higher PTSD risk. Our study illustrates the need for a more systematic examination of sex differences in contributors to PTSD severity after trauma, which may inform refined preventive interventions.	2942/2942	Primary Analysis	Shared
Defining the r factor for post-trauma resilience and its neural predictors	10.15154/zwyn-rb26	Although resilience is a dynamic process of recovery after trauma, in most studies it is conceptualized as the absence of specific psychopathology following trauma. Using the emergency department AURORA study (n = 1,865 with 63% women), we took a longitudinal, dynamic and transdiagnostic approach to define a static resilience (r) factor, which could explain greater than 50% of variance in mental well-being 6 months following trauma and a dynamic resilience factor, which represented recovery from initial symptoms. Here we assess its neurobiological profile across threat, inhibition and reward processes using functional magnetic resonance imaging collected 2 weeks post-trauma (n = 260). Our whole-brain and study-wide Bonferroni-corrected results suggest that resilience is promoted by activation of regions involved in higher-level cognitive functioning, reward valuation and salience detection in response to reward, whereas resilience is hampered by posterior default mode network activation to threat and reward. These findings serve to generate new hypotheses for brain mechanisms that could promote dynamic and multifaceted components of resilience following trauma.	1835/1835	Primary Analysis	Shared
Social buffering of PTSD: A longitudinal neuroimaging analysis	10.15154/4kxb-z177	Background: Post-traumatic stress disorder (PTSD) is a well characterized psychiatric disorder featuring changes in mood and arousal following traumatic events. Prior animal and human studies on social support in the peri-traumatic window demonstrate a buffering effect with regards to acute biological and psychological stress symptoms. Fewer studies have explored the magnitude and mechanism on how early, post-trauma social support can reduce longitudinal PTSD severity. Methods: In this study we investigated the beneficial impact of social support on longitudinal PTSD symptoms, and probed brain regions sensitive to this buffering phenomenon, such as the amygdala and ventromedial prefrontal cortex. In the multi-site AURORA study, n=315 participants reported PTSD symptoms (PCL-5) and perceived emotional support (PROMIS) at 2-weeks, 8-weeks, 3-months, and 6-months post-ED visit. Additionally, neuroimaging data was collected at 2 weeks post trauma. Results: We hypothesized that early, post-trauma social support would be linked with greater fractional anisotropic (FA) values in white matter tracts that have known connectivity between the amygdala and prefrontal cortex and would predict reduced neural reactivity to social threat cues in the amygdala. Interestingly, while we observed greater FA in the bilateral cingulum and bilateral uncinate fasciculus as a function of early post-trauma emotional support, we also identified greater threat reactivity in the precuneus/posterior cingulate, a component of the default mode network. Conclusion: Our findings suggest that the neurocircuitry underlying the response to social threat cues are facilitated through broader pathways that involve the posterior hub of the default mode network.	314/314	Secondary Analysis	Shared
Sequential decreases in basolateral amygdala response to threat predict failure to recover from PTSD	10.15154/5t8n-fj46	Amygdala hyperreactivity early-post trauma has been a demonstrable neurobiological correlate of future posttraumatic stress disorder (PTSD). The basolateral amygdala (BLA) particularly is vital for fear memory and threat processing, but BLA functional dynamics following a traumatic event are unexplored. BLA reactivity to threat may be a trait that can predict PTSD and persist over time. Alternatively, BLA responsivity to threat cues may change over time and be related to PTSD severity. As part of a larger, multisite study, AURORA, participants 18-75 years old were enrolled in an emergency department (ED) within 72 hours of a traumatic event (N=304, 199 female). At 2-weeks and 6-months post-trauma, PTSD symptoms, BLA responses to threat (fearful>neutral faces), and functional connectivity (FC) during fMRI were assessed. Generalizability of findings was assessed in an external replication sample of ED patients (n=33). Two weeks post-trauma right BLA reactivity positively predicted later PTSD severity. However, left BLA reactivity to threat at 6 months post-trauma was negatively associated with PTSD severity at that timepoint (∆Pseudo-R2=0.04, IRR=0.38, p<0.001). In addition, a decrease in BLA reactivity from 2-weeks to 6-months predicted greater PTSD severity at 6 months (∆Pseudo-R2=0.03, IRR=0.58, p<0.001). This replicated in the external sample. A reduction in left BLA FC with the dorsal attention network predicted increased PTSD severity over time. These findings support a shift in BLA function within the first 6 months post-trauma that predicts PTSD pathology and stand in contrast to prior conceptualizations of amygdala hyperreactivity as a trait-like PTSD risk factor.	304/304	Primary Analysis	Shared
Reward neurocircuitry predicts longitudinal changes in alcohol use following trauma exposure	10.15154/hv6e-7z12	Background: Trauma is a risk factor for developing maladaptive alcohol use. Preclinical research has shown that stress alters the processing of striatal reward and motivation signals. However, little research has been conducted on alterations in reward-related neurocircuitry post-trauma in humans. Given this, the current study aimed to uncover the underlying reward-related neural mechanisms associated with changes in alcohol use after trauma exposure. Methods: Participants were recruited from emergency departments (ED) around the U.S. as part of the AURORA study (N=286, 178 female). Trauma-related change in alcohol use was quantified as the change in 30-day total drinking at 8 weeks relative to pre-trauma as measured with the PhenX Toolkit. Reward-related neurocircuitry activation and functional connectivity (FC) was assessed 2 weeks post-trauma using fMRI during a monetary reward task using region of interest and whole-brain voxelwise analyses. Results: Greater alcohol use from pre-trauma to 8 weeks post-trauma was predicted by (1) greater ventral tegmental area (VTA) activation during Gain>Loss trials measured 2 weeks post-trauma, (2) greater cerebellum activation, and (3) greater seed-based FC between the VTA seed and lateral occipital cortex and precuneus. Conclusions: Altered VTA activation and FC early post-trauma could lead to deficits in reward-seeking and processing, contributing to greater alcohol use post-trauma. These data provide novel evidence of neural mechanisms that underlie increased alcohol use early post-trauma that can be targeted via early interventions to prevent the development of an alcohol use disorder.	286/286	Primary Analysis	Shared
Sex differences in response inhibition-related neural predictors of PTSD in recent trauma-exposed civilians	10.15154/5mpz-r032	Background: Females are more likely to develop posttraumatic stress disorder (PTSD) than males. Impaired inhibition has been identified as mechanism for PTSD development, but studies on the potential sex differences of this neurobiological mechanism and how it relates to PTSD severity and progression are sparse. Here we examined sex differences in neural activation during response inhibition and PTSD following recent trauma. Methods: Participants (N= 205, 138 female sex assigned at birth) were recruited from emergency departments within 72 hours of a traumatic event. PTSD symptoms were assessed 2-weeks and 6-months post-trauma. A Go/NoGo task was performed 2-weeks post-trauma in a 3T MRI scanner to measure neural activity during response inhibition in the ventromedial prefrontal cortex (vmPFC), right inferior frontal gyrus (rIFG), and the bilateral hippocampus. General Linear models were used to examine the interaction effect of sex on the relationship between our regions of interest (ROIs) and the whole brain, and PTSD symptoms at 6-months, and symptom progression between 2-weeks and 6-months. Results: Lower response-inhibition-related vmPFC activation 2-weeks post-trauma predicted more PTSD symptoms at 6-months in females but not in males, while greater response-inhibition-related rIFG activation predicted lower PTSD symptom progression in males but not females. Whole brain interaction effects were observed in the medial temporal gyrus and left precentral gyrus. Conclusions: There are sex differences in the relationship between inhibition-related brain activation and PTSD symptom severity and progression. These findings suggest that sex differences should be assessed in future PTSD studies and reveal potential targets for sex-specific interventions.	205/205	Primary Analysis	Shared

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