NDA Help Center

Collection - General Tab

Fields available for edit on the top portion of the page include:

  • Collection Title
  • Investigators
  • Collection Description
  • Collection Phase
  • Funding Source
  • Clinical Trials

Collection Status: The visibility status of an NDA Collection.  Collection Status can be Shared or Private.  Collections in Shared status are visible to all users and can be searched in the NDA Query Tool. Private Collections are not visible to NDA users.  The Status of an NDA Collection only affects the visibility of information about the Collection (metadata) and does not relate to the status of the record-level research data in the NDA Collection.

Collection Phase: The current status of a research project submitting data to an NDA Collection, based on the timing of the award and/or the data that have been submitted.
 

  • Pre-Enrollment: The default entry made when the NDA Collection is created.
     
  • Enrolling: Data have been submitted to the NDA Collection or the NDA Data Expected initial submission date has been reached for at least one data structure category in the NDA Collection.
     
  • Data Analysis: Subject level data collection for the research project is completed and has been submitted to the NDA Collection.  The NDA Collection owner or the NDA Help Desk may set this phase when they’ve confirmed data submission is complete and submitted subject counts match at least 90% of the target enrollment numbers in the NDA Data Expected. Data submission reminders will be turned off for the NDA Collection.
     
  • Funding Completed: The NIH grant award (or awards) associated with the NDA Collection has reached its end date. NDA Collections in Funding Completed phase are assigned a subphase to indicate the status of data submission.
     
    • The Data Expected Subphase indicates that NDA expects more data will be submitted
    • The Closeout Subphase indicates the data submission is complete.
    • The Sharing Not Met Subphase indicates that data submission was not completed as expected. 

Blinded Clinical Trial Status:

  • This status is set by a Collection Owner and indicates the research project is a double blinded clinical trial.  When selected, the public view of Data Expected will show the Data Expected items and the Submission Dates, but the targeted enrollment and subjects submitted counts will not be displayed.
     
  • Targeted enrollment and subjects submitted counts are visible only to NDA Administrators and to the NDA Collection or as the NDA Collection Owner.
     
  • When an NDA Collection that is flagged Blinded Clinical Trial reaches the maximum data sharing date for that Data Repository (see https://nda.nih.gov/about/sharing-regimen.html), the embargo on Data Expected information is released.
     

Funding Source

The organization(s) responsible for providing the funding is listed here. 

Supporting Documentation

Users with Submission privileges, as well as Collection Owners, Program  Officers, and those with Administrator privileges, may upload and attach supporting documentation. By default, supporting documentation is shared to the general public, however, the option is also available to limit this information to qualified researchers only. 

Grant Information 

Identifiable details are displayed about the Project of which the Collection was derived from. You may click in the Project Number to view a full report of the Project captured by the NIH. 

Clinical Trials

Any data that is collected to support or further the research of clinical studies will be available here. Collection Owners and those with Administrator privileges may add new clinical trials. 

Frequently Asked Questions

  • When a Collection is created by NDA staff and marked as Shared, an email notification will automatically be sent to the PI(s) of the grant(s) associated with the Collection to notify them.

  • During Collection creation, NDA staff determine the appropriate Permission Group based on the type of data to be submitted, the type of access that will be available to data access users, and the information provided by the Program Officer during grant award.

  • The NDA system does not allow for a single grant to be associated with more than one Collection; therefore, a single grant will not be listed in the Grant Information section of a Collection for more than one Collection.

  • In general, each Collection is associated with only one grant; however, multiple grants may be associated if the grant has multiple competing segments for the same grant number or if multiple different grants are all working on the same project and it makes sense to hold the data in one Collection (e.g., Cooperative Agreements).

Glossary

  • Number of human subjects enrolled in an NIH-funded clinical research study. The data is provided in annual progress reports.

  • A privilege provided to a user associated with an NDA Collection or NDA Study whereby that user can perform a full range of actions including providing privileges to other users. 

  • Generally, the Collection Owner is the contact PI listed on a grant. Only one NDA user is listed as the Collection owner. Most automated emails are primarily sent to the Collection Owner.

  • The Collection Phase provides information on data submission as opposed to grant/project completion so while the Collection phase and grant/project phase may be closely related they are often different.  Collection users with Administrative Privileges are encouraged to edit the Collection Phase.  The Program Officer as listed in eRA (for NIH funded grants) may also edit this field. Changes must be saved by clicking the Save button at the bottom of the page.  This field is sortable alphabetically in ascending or descending order. Collection Phase options include: 

    • Pre-Enrollment:  A grant/project has started, but has not yet enrolled subjects.
    • Enrolling:  A grant/project has begun enrolling subjects.  Data submission is likely ongoing at this point.
    • Data Analysis:  A grant/project has completed enrolling subjects and has completed all data submissions.
    • Funding Completed:  A grant/project has reached the project end date.
  • The Collection State indicates whether the Collection is viewable and searchable.  Collections can be either Private, Shared, or an Ongoing Study.  A Collection that is shared does not necessarily have shared data as the Collection State and state of data are independent of each other.  This field can be edited by Collection users with Administrative Privileges and the Program Officer as listed in eRA (for NIH funded grants). Changes must be saved by clicking the Save button at the bottom of the page.

  • An editable field with the title of the Collection, which is often the title of the grant associated with the Collection.

  • Data Use Limitations (DULs) describe the appropriate secondary use of a dataset and are based on the original informed consent of a research participant. NDA only accepts consent-based data use limitations defined by the NIH Office of Science Policy.

  • Provides the grant number(s) for the grant(s) associated with the Collection.  The field is a hyperlink so clicking on the Grant number will direct the user to the grant information in the NIH Research Portfolio Online Reporting Tools (RePORT) page.

  • A virtual container and organization structure for data and associated documentation from one grant or one large project/consortium. It contains tools for tracking data submission and allows investigators to define a wide array of other elements that provide context for the data, including all general information regarding the data and source project, experimental parameters used to collect any event-based data contained in the Collection, methods, and other supporting documentation. They also allow investigators to link underlying data to an NDA Study, defining populations and subpopulations specific to research aims. 

  • NDA Collections may be organized by scientific similarity into NIH Research Initiatives, to facilitate query tool user experience. NIH Research Initiatives map to one or multiple Funding Opportunity Announcements. 

  • Access to shared record-level data in NDA is provisioned at the level of a Permission Group. NDA Permission Groups consist of one or multiple NDA Collections that contain data with the same subject consents.

  • Number of human subject participants to be enrolled in an NIH-funded clinical research study. The data is provided in competing applications and annual progress reports.

  • Various documents and materials to enable efficient use of the data by investigators unfamiliar with the project and may include the research protocol, questionnaires, and study manuals.  

  • The total number of unique subjects for whom data have been shared and are available for users with permission to access data.

NDA Help Center

Collection - Shared Data Tab

This tab provides a quick overview of the Data Structure title, Data Type, and Number of Subjects that are currently Shared for the Collection. The information presented in this tab is automatically generated by NDA and cannot be edited. If no information is visible on this tab, this would indicate the Collection does not have shared data or the data is private.

The shared data is available to other researchers who have permission to access data in the Collection's designated Permission Group(s). Use the Download button to get all shared data from the Collection to the Filter Cart.

 

Frequently Asked Questions

  • To see what data your project have submitted are being used by a study, simply go the Associated Studies tab of your collection.  Alternatively, you may review an NDA Study Attribution Report available on the General tab.  

  • Often it becomes more difficult to organize and format data electronically after the project has been completed and the information needed to create a GUID may not be available; however, you may still contact a program staff member at the appropriate funding institution for more information.

  • Unlike completed projects where researchers may not have the information needed to create a GUID and/or where the effort needed to organize and format data becomes prohibitive, ongoing projects have more of an opportunity to overcome these challenges.  Please contact a program staff member at the appropriate funding institution for more information.

Glossary

  • A defined organization and group of Data Elements to represent an electronic definition of a measure, assessment, questionnaire, or collection of data points. Data structures that have been defined in the NDA Data Dictionary are available at https://nda.nih.gov/general-query.html?q=query=data-structure

  • A grouping of data by similar characteristics such as Clinical Assessments, Omics, or Neurosignal data.

  • The term 'Shared' generally means available to others; however, there are some slightly different meanings based on what is Shared.  A Shared NDA Collection or NDA Study is viewable and searchable publicly regardless of the user's role or whether the user has an NDA account.  A Shared Collection or NDA Study does not necessarily mean that data submitted to the Collection or used in the NDA Study have been shared as this is independently determined.  Data are shared according the schedule defined in a Collection's Data Expected Tab and/or in accordance with data sharing expectations in the NDA Data Sharing Terms and Conditions.  Additionally, Supporting Documentation uploaded to a Collection may be shared independent of whether data are shared, but will only be viewable and accessible if the Collection is Shared.

NDA Help Center

fMRi

fMRI stands for functional magnetic resonance imaging. fMRI tests measure blood flow, providing detailed functional images of the brain or body. 

Acquisition
The Acquisition parameters needed for an experiment include the following:

The name of the experiment is required. Please be concise and specific as possible.
Following experiment name, selection boxes are provided for the Equipment, Software, or other items specific to the experiment type. At least one selection is required for each. If NDAR does not have the appropriate listing, select Add New to add the information provided. Following the selection boxes, provide additional information may be required depending on the experiment type. Any required items are denoted by an asterisk (*).

Block/Event Design
At least one block/event is required. Note that any fields denoted with an asterisk (*) are required. All data must be devoid of personally identifiable data, including the contents of any files attached to the experiment.

Note: To simplify the definition of multiple events, we provide an Import from XML function. This function supports importing data from all three experiment sections (Acquisition, Block/Event Design, and Post Processing), at this time files cannot be uploaded from XML A test format is provided here and our XML Schema Definition (xsd) can be found here.

Post Processing
If you have completed any post-processing on your data, please choose 'Yes' for Has Postprocessing? If not, select 'No'. Depending on this selection the remaining post-processing fields will be enabled (some of which will be required). If you are initially providing data you can select 'No', then return to the experiment to add post-processing steps at a later date when the data are being provided.

Please provide information about post-processing manipulations, i.e. artifact detection algorithms, segmentation used for post data collection, items denoted with an asterisk (*) are required.

Frequently Asked Questions

Glossary

  • This button will add all selections to the Filter Cart. 

  • This button will allow you to copy all of the Experiment details as a template for a new experiment. 

  • Adds all data from the current selections in a Collection or NDA Study to the Filter Cart.

  • This button will allow you to return to the Experiments tab. 

NDA Help Center

Collection - Submissions Tab

Users with permission to access Shared data in the Collection’s assigned Permission Group may use this tab. 

Here, you can:

  • Review your uploads to your Collection, monitor their status, and download them individually to verify their contents.
  • Download individual datasets as a secondary user of the data approved for access.
  • Identify and download datasets containing errors identified by NDA's QA/QC process for review and resolution.
  • Report suspected or discovered Personally Identifiable Information in a submission via the Actions column.

Frequently Asked Questions

Glossary

  • The default view of Datasets within a Collection's Submission tab.

  • A Submission Loading Status on a Collection's Submission Tab that indicates that an issue has prevented the successful loading of the submission.  Users should contact the NDA Help Desk for assistance at NDAHelp@mail.nih.gov.

  • The NDA has two Submission Cycles per year - January 15 and July 15.

  • An interface to notify NDA that data may not be submitted during the upcoming/current submission cycle.  

  • The unique and sequentially assigned ID for a submission (e.g. a discrete upload via the Validation and Upload Tool), which may contain any number of datafiles, Data Structures and/or Data Types, regardless of the Submission Loading Status. A single submission may be divided into multiple Datasets, which are based on Data Type.

  • The total number of unique subjects for whom data have been shared and are available for users with permission to access data.

  • The total number of unique subjects for whom data have been submitted, which includes data in both a Private State and a Shared State.

NDA Help Center

Collection - Publications Tab

The number of Publications is displayed in parentheses next to the tab name. Clicking on any of the Publication Titles will open the Publication in a new internet browsing tab. 

Collection Owners, Program Officers, and users with Submission or Administrative Privileges for the Collection may mark a publication as either Relevant or Not Relevant in the Status column. 

 

Frequently Asked Questions

  • Publications are considered relevant to a collection when the data shared is directly related to the project or collection.

  • PubMed, an online library containing journals, articles, and medical research. Sponsored by NiH and National Library of Medicine (NLM). 

Glossary

  • A link to the Create an NDA Study page that can be clicked to start creating an NDA Study with information such as the title, journal and authors automatically populated.

  • Indicates that the publication has not yet been reviewed and/or marked as Relevant or Not Relevant so it has not been determined whether an NDA Study is expected.

  • A publication that is not based on data related to the aims of the grant/project associated with the Collection or not based on any data such as a review article and, therefore, an NDA Study is not expected to be created.

  • PubMed provides citation information for biomedical and life sciences publications and is managed by the U.S. National Institutes of Health's National Library of Medicine.

  • The PUBMed ID is the unique ID number for the publication as recorded in the PubMed database.  

  • A publication that is based on data related to the aims of the grant/project associated with the Collection and, therefore, an NDA Study is expected to be created.

NDA Help Center

EEG

EEG stands for electroencencephalogram and is a test used to measure electrical activity in the brain.

Acquisition
The Acquisition parameters needed for an experiment include the following:

Name of the experiment is required. Please be concise and specific as possible.
Following experiment name, selection boxes are provided for the Equipment, Software, or other items specific to experiment type. At least one selection is required for each. If NDAR does not have the appropriate listing, select Add New to add the information provided. Following the selection boxes, provide additional information may be required depending on experiment type. Any required items are denoted by an asterisk (*).

Block/Event Design
At least one block/event is required. Note that any fields denoted with an asterisk (*) are required. All data must be devoid of personally identifiable data, including the contents of any files attached to the experiment.

Note: To simplify definition of multiple events, we provide an Import from XML function. This function supports importing data from all three experiment sections (Acquisition, Block/Event Design, and Post Processing), at this time files cannot be uploaded from XML A test format is provided here and our XML Schema Definition (xsd) can be found here.

Post Processing
If you have completed any post processing on your data, please choose 'Yes' for Has Postprocessing? If not, select 'No'. Depending on this selection the remaining post processing fields will be enabled (some of which will be required). If you are initially providing data you can select 'No', then return to the experiment to add post processing steps at a later date when the data are being provided.

Please provide information about post-processing manipulations, i.e. artifact detection algorithms, segmentation used for post data collection, items denoted with an asterisk (*) are required.

Frequently Asked Questions

Glossary

  • This button will add all selections to the Filter Cart. 

  • This button will allow you to copy all of the Experiment details as a template for a new experiment. 

  • Adds all data from the current selections in a Collection or NDA Study to the Filter Cart.

  • This button will allow you to return to the Experiments tab. 

NDA Help Center

Collection - Data Expected

The Data Expected tab displays the list of all data that NDA expects to receive in association with the Collection as defined by the contributing researcher, as well as the dates for the expected initial upload of the data, and when it is first expected to be shared, or with the research community. Above the primary table of Data Expected, any publications determined to be relevant to the data within the Collection are also displayed - members of the contributing research group can use these to define NDA Studies, connecting those papers to underlying data in NDA.

The tab is used both as a reference for those accessing shared data, providing information on what is expected and when it will be shared, and as the primary tracking mechanism for contributing projects. It is used by both contributing primary researchers, secondary researchers, and NIH Program and Grants Management staff.

Contributing researchers just getting started on their project will need to define this list by adding all of the items they are collecting under their grant and setting their schedule according to the NDA Data Sharing Regimen. If you fall into this category, you can begin by clicking "add new Data Expected" and selecting which data structures you will be using, saving the page after each change, or requesting new structures by adding and naming a new item, providing any materials NDA Data Dictionary Curators can use to help define your structure. For more information see the tutorial on creating Data Expected.

If you are a contributing researcher creating this list for the first time, or making changes to the list as your project progress, please note the following:

  • Although items you add to the list and changes you make are displayed, they are not committed to the system until you Save the entire page using the "Save" button at the bottom of your screen. Please Save after every change to ensure none of your work is lost.
  • If you attempt to add a new structure, the title you provide must be unique - if another structure exists with the same name your change will fail.
  • Adding a new structure to this list is the only way to request the creation of a new Data Dictionary definition.

 

Frequently Asked Questions

  • An NDA Data Structure is comprised of multiple Data Elements to make up an electronic definition of an assessment, measure, questionnaire, etc will have a corresponding Data Structure.

  • The NDA Data Dictionary is comprised of electronic definitions known as Data Structures.

Glossary

  • Data specific to the primary aims of the research being conducted (e.g. outcome measures, other dependent variables, observations, laboratory results, analyzed images, volumetric data, etc.) including processed images.

  • Items listed on the Data Expected list in the Collection which may be an individual and discrete Data Structure, Data Structure Category, or Data Structure Group.

  • A defined organization and group of Data Elements to represent an electronic definition of a measure, assessment, questionnaire, or collection of data points. Data structures that have been defined in the NDA Data Dictionary are available at https://nda.nih.gov/general-query.html?q=query=data-structure

  • An NDA term describing the affiliation of a Data Structure to a Category, which may be disease/disorder or diagnosis related (Depression, ADHD, Psychosis), specific to data type (MRI, eye tracking, omics), or type of data (physical exam, IQ).

  • A Data Item listed on the Data Expected tab of a Collection that indicates a group of Data Structures (e.g., ADOS or SCID) for which data may be submitted instead of a specific Data Structure identified by version, module, edition, etc. For example, the ADOS Data Structure Category includes every ADOS Data Structure such as ADOS Module 1, ADOS Module 2, ADOS Module 1 - 2nd Edition, etc. The SCID Data Structure Group includes every SCID Data Structure such as SCID Mania, SCID V Mania, SCID PTSD, SCID-V Diagnosis, and more. 

  • A new Data Structure category, Evaluated Data is analyzed data resulting from the use of computational pipelines in the Cloud and can be uploaded directly back to a miNDAR database.  Evaluated Data is expected to be listed as a Data Item in the Collection's Data Expected Tab.

  • Imaging+ is an NDA term which encompasses all imaging related data including, but not limited to, images (DTI, MRI, PET, Structural, Spectroscopy, etc.) as well as neurosignal data (EEG, fMRI, MEG, EGG, eye tracking, etc.) and Evaluated Data.

  • Initial Submission and Initial Share dates should be populated according to the NDA Data Sharing Terms and Conditions. Any modifications to these will go through the approval processes outlined above. Data will be shared with authorized users upon publication (via an NDA Study) or 1-2 years after the grant end date specified on the first Notice of Award, as defined in the applicable Data Sharing Terms and Conditions.

  • Initial Submission and Initial Share dates should be populated according to these NDA Data Sharing Terms and Conditions. Any modifications to these will go through the approval processes outlined above. Data for all subjects is not expected on the Initial Submission Date and modifications may be made as necessary based on the project's conduct.

  • An NDA created Data Structure used to convey basic information about the subject such as demographics, pedigree (links family GUIDs), diagnosis/phenotype, and sample location that are critical to allow for easier querying of shared data.

  • The NDA has two Submission Cycles per year - January 15 and July 15.

  • An interface to notify NDA that data may not be submitted during the upcoming/current submission cycle.  

NDA Help Center

Collection - Permissions

Collection Owners, Program Officers, and users with Administrator privileges may view this tab.

The available permission groups include:

  • Query: This read-only access is generally for NIH Program Officers
  • Submission: This will grant read access and allow the user to upload data and create experiment definitions. This is for the typical contributing personnel member.
  • Administrator: In addition to the access provided to Query and Submission users, Admins can also edit the Collection itself, create or edit the Data Expected list, and edit user permissions. This access is for the PI, data managers, and anyone they wish to delegate this to.

The PI has a special designation as the Collection Owner in addition to administrator access.

Frequently Asked Questions

  • Collection Owners and Admins may assign Collection Privileges to anyone.

  • Yes, you can assign various Privileges to other users with an NDA account.

  • If you are the Collection Owner or have Admin privileges, you can view and make changes to the list of individuals who have access to the Collection on the Collection's Permissions tab.  Information on users who have access to data Shared in your Collection because they were granted access to a Permission Group is not available.

  • Staff/collaborators who are working submitting data to the Collection, checking the quality of the data, and/or analyzing data should have access for the duration of the project until all data have been submitted, NDA Studies have been created for data used in publications, and/or a collaborative relationship with the user exists.  

  • The individual listed as an Investigator on the General tab of the NDA Collection will generally be able to provide a user access to the NDA Collection.  Additional users may also have this ability if granted Administrator access to an NDA Collection; however, these users are not viewable unless your account has access to the NDA Collection.  Given this, it is best to contact the Investigator to request access to the Collection.

  • Privileges that can be assigned to a user include:
    Submission allows a user to submit data to Collection
    Query allows the user to download data from Collection even when in a Private state
    Admin is both the Submission and Query Privilege + the ability to give privileges to other users.

  • You may have staff who are working on the submission of data or other activities associated with data sharing such as the definition of the Data Expected list or NDA Experiment creation.  Also, many projects have multiple performance sites and wish to share data among the site PIs.  Submitting to the NDA facilitates access by all investigators working on a project even before data have been shared with other users.  You can control who gets access to data while in a Private state.

Glossary

  • A privilege provided to a user associated with an NDA Collection or NDA Study whereby that user can perform a full range of actions including providing privileges to other users. 

  • Access to shared record-level data in NDA is provisioned at the level of a Permission Group. NDA Permission Groups consist of one or multiple NDA Collections that contain data with the same subject consents.

NDA Help Center

Eye Tracking

EyeTracking tests follow the movement of the eye. The visual trajectory or focus can help determine predictions and assist in diagnoses. 

Acquisition
The Acquisition parameters needed for an experiment include the following:

The name of the experiment is required. Please be concise and specific as possible.
Following experiment name, selection boxes are provided for the Equipment, Software, or other items specific to the experiment type. At least one selection is required for each. If NDAR does not have the appropriate listing, select Add New to add the information provided. Following the selection boxes, provide additional information may be required depending on the experiment type. Any required items are denoted by an asterisk (*).

Block/Event Design
At least one block/event is required. Note that any fields denoted with an asterisk (*) are required. All data must be devoid of personally identifiable data, including the contents of any files attached to the experiment.

Note: To simplify the definition of multiple events, we provide an Import from XML function. This function supports importing data from all three experiment sections (Acquisition, Block/Event Design, and Post Processing), at this time files cannot be uploaded from XML A test format is provided here and our XML Schema Definition (xsd) can be found here.

Post Processing
If you have completed any post-processing on your data, please choose 'Yes' for Has Postprocessing? If not, select 'No'. Depending on this selection the remaining post-processing fields will be enabled (some of which will be required). If you are initially providing data you can select 'No', then return to the experiment to add post-processing steps at a later date when the data are being provided.

Please provide information about post-processing manipulations, i.e. artifact detection algorithms, segmentation used for post data collection, items denoted with an asterisk (*) are required.

Frequently Asked Questions

Glossary

  • This button will add all selections to the Filter Cart. 

  • This button will allow you to copy all of the Experiment details as a template for a new experiment. 

  • Adds all data from the current selections in a Collection or NDA Study to the Filter Cart.

  • This button will allow you to return to the Experiments tab. 

NDA Help Center

Collection - Experiments Tab

The number of Experiments included is displayed in parentheses next to the tab name. You may download all experiments associated with the Collection via the Download button. You may view individual experiments by clicking the Experiment Name and add them to the Filter Cart via the Add to Cart button.

Collection Owners, Program Officers, and users with Submission or Administrative Privileges for the Collection may create or edit an Experiment.

Please note: The creation of an NDA Experiment does not necessarily mean that data collected, according to the defined Experiment, has been submitted or shared.

Frequently Asked Questions

  • Yes -see the “Copy” button in the bottom left when viewing an experiment. There are two actions that can be performed via this button:

    1. Copy the experiment with intent for modifications.  
    2. Associate the experiment to the collection. No modifications can be made to the experiment.

     

Glossary

  • An Experiment must be Approved before data using the associated Experiment_ID may be uploaded.

  • The ID number automatically generated by NDA which must be included in the appropriate file when uploading data to link the Experiment Definition to the subject record.

NDA Help Center

Omics

Omics is a collective group of technologies, related to a field of study in Biology such as Genomics or proteomics. 

Experiment Parameters

To define an Omics experiment, provide a meaningful name and select a single molecule. The standard molecules are listed. However, if you are doing proteomic or environmental experiments, simply “Add New” and the new selection will be created. Only one value for molecule is permitted.

Next the technology (box 2) associated with the molecule will be presented along with its application. Again, only one selection is possible. If you wish to see all of NDAR’s options for any one box, Select “Show All”.

Platform

Continue to select the Platform (box 3).

Extraction

Next, the Extraction Protocol (box 4) and Kits (box 5) are presented based upon the Molecule selected and the Processing Protocol (box 6) and Kits (box 7) are presented based upon the Molecule and Technology Application (Box 1 and 2)

Processing

Note that for each of these (boxes 4, 5, 6, and 7) multiple selections are possible.

Additional Information

Lastly, the Software (box 8) and Equipment (box 9) is expected.

 

Once saved, the experiment will be associated with the Collection and by using the returned Experiment_ID, the NDA makes it possible to associate the experiment meta data directly with the data from the experiment.

Frequently Asked Questions

Glossary

  • This button will add all selections to the Filter Cart. 

  • This button will allow you to copy all of the Experiment details as a template for a new experiment. 

  • Adds all data from the current selections in a Collection or NDA Study to the Filter Cart.

  • This button will allow you to return to the Experiments tab. 

NDA Help Center

Collection - Associated Studies

Clicking on the Study Title will open the study details in a new internet browser tab. The Abstract is available for viewing, providing the background explanation of the study, as provided by the Collection Owner. 

Primary v. Secondary Analysis: The Data Usage column will have one of these two choices. An associated study that is listed as being used for Primary Analysis indicates at least some and potentially all of the data used was originally collected by the creator of the NDA Study. Secondary Analysis indicates the Study owner was not involved in the collection of data, and may be used as supporting data. 

Private v. Shared State: Studies that remain private indicate the associated study is only available to users who are able to access the collection. A shared study is accessible to the general public. 

Frequently Asked Questions

  • Studies are associated to the Collection automatically when the data is defined in the Study. 

Glossary

  • A tab in a Collection that lists the NDA Studies that have been created using data from that Collection including both Primary and Secondary Analysis NDA Studies.

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Format should be in the following format: Activity Code, Institute Abbreviation, and Serial Number. Grant Type, Support Year, and Suffix should be excluded. For example, grant 1R01MH123456-01A1 should be entered R01MH123456

Please select an experiment type below

Collection - Use Existing Experiment

To associate an experiment to the current collection, just select an axperiment from the table below then click the associate experiment button to persist your changes (saving the collection is not required). Note that once an experiment has been associated to two or more collections, the experiment will not longer be editable.

The table search feature is case insensitive and targets the experiment id, experiment name and experiment type columns. The experiment id is searched only when the search term entered is a number, and filtered using a startsWith comparison. When the search term is not numeric the experiment name is used to filter the results.

SelectExperiment IdExperiment NameExperiment Type
Created On
24HI-NGS_R1Omics02/16/2011
475MB1-10 (CHOP)Omics06/07/2016
490Illumina Infinium PsychArray BeadChip AssayOmics07/07/2016
501PharmacoBOLD Resting StatefMRI07/27/2016
506PVPREFOmics08/05/2016
509ABC-CT Resting v2EEG08/18/2016
13Comparison of FI expression in Autistic and Neurotypical Homo SapiensOmics12/28/2010
18AGRE/Broad Affymetrix 5.0 Genotype ExperimentOmics01/06/2011
22Stitching PCR SequencingOmics02/14/2011
26ASD_MethylationOmics03/01/2011
29Microarray family 03 (father, mother, sibling)Omics03/24/2011
37Standard paired-end sequencing of BCRsOmics04/19/2011
38Illumina Mate-Pair BCR sequencingOmics04/19/2011
39Custom Jumping LibrariesOmics04/19/2011
40Custom CapBPOmics04/19/2011
41ImmunofluorescenceOmics05/11/2011
43Autism brain sample genotyping, IlluminaOmics05/16/2011
47ARRA Autism Sequencing Collaboration at Baylor. SOLiD 4 SystemOmics08/01/2011
53AGRE Omni1-quadOmics10/11/2011
59AGP genotypingOmics04/03/2012
60Ultradeep 454 sequencing of synaptic genes from postmortem cerebella of individuals with ASD and neurotypical controlsOmics06/23/2012
63Microemulsion PCR and Targeted Resequencing for Variant Detection in ASDOmics07/20/2012
76Whole Genome Sequencing in Autism FamiliesOmics01/03/2013
90Genotyped IAN SamplesOmics07/09/2013
91NJLAGS Axiom Genotyping ArrayOmics07/16/2013
93AGP genotyping (CNV)Omics09/06/2013
106Longitudinal Sleep Study. H20 200. Channel set 2EEG11/07/2013
107Longitudinal Sleep Study. H20 200. Channel set 3EEG11/07/2013
108Longitudinal Sleep Study. AURA 200EEG11/07/2013
105Longitudinal Sleep Study. H20 200. Channel set 1EEG11/07/2013
109Longitudinal Sleep Study. AURA 400EEG11/07/2013
116Gene Expression Analysis WG-6Omics01/07/2014
131Jeste Lab UCLA ACEii: Charlie Brown and Sesame Street - Project 1Eye Tracking02/27/2014
132Jeste Lab UCLA ACEii: Animacy - Project 1Eye Tracking02/27/2014
133Jeste Lab UCLA ACEii: Mom Stranger - Project 2Eye Tracking02/27/2014
134Jeste Lab UCLA ACEii: Face Emotion - Project 3Eye Tracking02/27/2014
145AGRE/FMR1_Illumina.JHUOmics04/14/2014
146AGRE/MECP2_Sanger.JHUOmics04/14/2014
147AGRE/MECP2_Junior.JHUOmics04/14/2014
151Candidate Gene Identification in familial AutismOmics06/09/2014
152NJLAGS Whole Genome SequencingOmics07/01/2014
154Math Autism Study - Vinod MenonfMRI07/15/2014
155RestingfMRI07/25/2014
156SpeechfMRI07/25/2014
159EmotionfMRI07/25/2014
160syllable contrastEEG07/29/2014
167School-age naturalistic stimuliEye Tracking09/19/2014
44AGRE/Broad Affymetrix 5.0 Genotype ExperimentOmics06/27/2011
45Exome Sequencing of 20 Sporadic Cases of Autism Spectrum DisorderOmics07/15/2011
78MET GenotypesOmics03/18/2013
Collection - Add Experiment
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Your Collection is now in Data Analysis phase and exempt from biannual submissions. Analyzed data is still expected prior to publication or no later than the project end date.

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Collection Summary Collection Charts
Collection Title Collection Investigators Collection Description
Bipolar & Schizophrenia Consortium for Parsing Intermediate Phenotypes (B-SNIP 1)
Carol Tamminga 
The overall goal of the proposed research is to examine a broad panel of putative endophenotypes in affected individuals with schizophrenia and bipolar and their unaffected relatives in order to: 1) characterize the degree of familial phenotypic overlap between SZ and psychotic BP; 2) identify patterns of endophenotypes unique t the two disorders, and 3) contrast the heritability of endophenotypes across the disorders. To achieve these goals, we will recruit 500 SZ and 500 BP I (with psychosis) probands, ~1700-2000 1st degree relative probands, and 500 unrelated non-psychiatric controls from five centers. We will obtain measures of neurophysiology (e.g., eye tracking, P50 gating, PPI, and P300), neurocognition (e.g., attention/vigilance, episodic and working memory), and brain structure (e.g., volumes of gray and white matter in specified brain regions). We will collect blood for future genetic studies. We will assess the degree of familial aggregation endophenotypes in SZ and BP relatives. Establishing similarities and differences in the endophenotypic signatures within SZ and BP families will provide important insights for future genetic studies, and clarify concepts about common and distinct aspects of pathophysiology, potentially meaningful heterogeneity with disorders, and the clinical boundaries of the two commonest psychotic disorders in adult psychiatry. This research will be conducted by 5 experienced research groups, with a long history of close and productive collaboration.
NIMH Data Archive
12/09/2014
Funding Completed
Close Out
Shared
No
$17,870,101.00
2,440
Loading Chart...
NIH - Extramural None


R01MH078113-01 Bipolar & Schizophrenia Consortium for Parsing Intermediate Phenotypes 09/28/2007 03/31/2020 640 215 BETH ISRAEL DEACONESS MEDICAL CENTER $4,082,240.00
R01MH077852-01 Bipolar & Schizophrenia Consortium for Parsing Intermediate Phenotypes 09/28/2007 05/31/2012 650 377 UNIVERSITY OF MARYLAND BALTIMORE $3,495,195.00
R01MH077851-01 Bipolar & Schizophrenia Consortium for Parsing Intermediate Phenotypes 09/29/2007 05/31/2013 650 263 UT SOUTHWESTERN MEDICAL CENTER $3,647,643.00
R01MH077945-01 Bipolar & Schizophrenia Consortium for Parsing Intermediate Phenotypes 09/29/2007 05/31/2013 650 365 YALE UNIVERSITY $3,518,485.00
R01MH077862-01 Bipolar & Schizophrenia Consortium for Parsing Intermediate Phenotypes 09/29/2007 05/31/2013 650 394 UT SOUTHWESTERN MEDICAL CENTER $3,126,538.00

helpcenter.collection.general-tab

NDA Help Center

Collection - General

Fields available for edit on the top portion of the page include:

  • Collection Title
  • Investigators
  • Collection Description
  • Collection Phase
  • Funding Source
  • Clinical Trials

Collection Status: The visibility status of an NDA Collection. Collection Status can be Shared or Private. Collections in Shared status are visible to all users and can be searched in the NDA Query Tool. Private Collections are not visible to NDA users. The Status of an NDA Collection only affects the visibility of information about the Collection (metadata) and does not relate to the status of the record-level research data in the NDA Collection.

Collection Phase: The current status of a research project submitting data to an NDA Collection, based on the timing of the award and/or the data that have been submitted.

  • Pre-Enrollment: The default entry made when the NDA Collection is created.
  • Enrolling: Data have been submitted to the NDA Collection or the NDA Data Expected initial submission date has been reached for at least one data structure category in the NDA Collection.
  • Data Analysis: Subject level data collection for the research project is completed and has been submitted to the NDA Collection. The NDA Collection owner or the NDA Help Desk may set this phase when they’ve confirmed data submission is complete and submitted subject counts match at least 90% of the target enrollment numbers in the NDA Data Expected. Data submission reminders will be turned off for the NDA Collection.
  • Funding Completed: The NIH grant award (or awards) associated with the NDA Collection has reached its end date. NDA Collections in Funding Completed phase are assigned a subphase to indicate the status of data submission.
    • The Data Expected Subphase indicates that NDA expects more data will be submitted
    • The Closeout Subphase indicates the data submission is complete.
    • The Sharing Not Met Subphase indicates that data submission was not completed as expected.

Blinded Clinical Trial Status:

  • This status is set by a Collection Owner and indicates the research project is a double blinded clinical trial. When selected, the public view of Data Expected will show the Data Expected items and the Submission Dates, but the targeted enrollment and subjects submitted counts will not be displayed.
  • Targeted enrollment and subjects submitted counts are visible only to NDA Administrators and to the NDA Collection or as the NDA Collection Owner.
  • When an NDA Collection that is flagged Blinded Clinical Trial reaches the maximum data sharing date for that Data Repository (see https://nda.nih.gov/about/sharing-regimen.html), the embargo on Data Expected information is released.

Funding Source

The organization(s) responsible for providing the funding is listed here.

Supporting Documentation

Users with Submission privileges, as well as Collection Owners, Program Officers, and those withAdministrator privileges, may upload and attach supporting documentation. By default, supporting documentation is shared to the general public, however, the optionis also available tolimit this information to qualified researchers only.

Grant Information

Identifiable details are displayed about the Project of which the Collection was derived from. You may click in the Project Number to view a full report of the Project capturedby the NIH.

Clinical Trials

Any data that is collected to support or further the research of clinical studies will be available here. Collection Owners and those with Administrator privileges may add new clinical trials.

Frequently Asked Questions

  • How do I know when a NDA Collection has been created?
    When a Collection is created by NDA staff and marked as Shared, an email notification will automatically be sent to the PI(s) of the grant(s) associated with the Collection to notify them.
  • How does the NIMH Data Archive (NDA) determine which Permission Group data are submitted into?
    During Collection creation, NDA staff determine the appropriate Permission Group based on the type of data to be submitted, the type of access that will be available to data access users, and the information provided by the Program Officer during grant award.
  • Is a single grant number ever associated with more than one Collection?
    The NDA system does not allow for a single grant to be associated with more than one Collection; therefore, a single grant will not be listed in the Grant Information section of a Collection for more than one Collection.
  • Why is there sometimes more than one grant included in a Collection?
    In general, each Collection is associated with only one grant; however, multiple grants may be associated if the grant has multiple competing segments for the same grant number or if multiple different grants are all working on the same project and it makes sense to hold the data in one Collection (e.g., Cooperative Agreements).

Glossary

  • Actual Enrollment
    Number of human subjects enrolled in an NIH-funded clinical research study. The data is provided in annual progress reports.
  • Administrator Privilege
    A privilege provided to a user associated with an NDA Collection or NDA Study whereby that user can perform a full range of actions including providing privileges to other users.
  • Collection Owner
    Generally, the Collection Owner is the contact PI listed on a grant. Only one NDA user is listed as the Collection owner. Most automated emails are primarily sent to the Collection Owner.
  • Data Use Limitations
    Data Use Limitations (DULs) describe the appropriate secondary use of a dataset and are based on the original informed consent of a research participant. NDA only accepts consent-based data use limitations defined by the NIH Office of Science Policy.
  • Grant
    Provides the grant number(s) for the grant(s) associated with the Collection. The field is a hyperlink so clicking on the Grant number will direct the user to the grant information in the NIH Research Portfolio Online Reporting Tools (RePORT) page.
  • NDA Collection
    A virtual container and organization structure for data and associated documentation from one grant or one large project/consortium. It contains tools for tracking data submission and allows investigators to define a wide array of other elements that provide context for the data, including all general information regarding the data and source project, experimental parameters used to collect any event-based data contained in the Collection, methods, and other supporting documentation. They also allow investigators to link underlying data to an NDA Study, defining populations and subpopulations specific to research aims.
  • Permission Group
    Access to shared record-level data in NDA is provisioned at the level of a Permission Group. NDA Permission Groups consist of one or multiple NDA Collections that contain data with the same subject consents.
  • Collection Phase
    The Collection Phase provides information on data submission as opposed to grant/project completion so while the Collection phase and grant/project phase may be closely related they are often different. Collection users with Administrative Privileges are encouraged to edit the Collection Phase. The Program Officer as listed in eRA (for NIH funded grants) may also edit this field. Changes must be saved by clicking the Save button at the bottom of the page. This field is sortable alphabetically in ascending or descending order. Collection Phase options include:
    • Pre-Enrollment: A grant/project has started, but has not yet enrolled subjects.
    • Enrolling: A grant/project has begun enrolling subjects. Data submission is likely ongoing at this point.
    • Data Analysis: A grant/project has completed enrolling subjects and has completed all data submissions.
    • Funding Completed: A grant/project has reached the project end date.
  • Planned Enrollment
    Number of human subject participants to be enrolled in an NIH-funded clinical research study. The data is provided in competing applications and annual progress reports.
  • NIH Research Initiative
    NDA Collections may be organized by scientific similarity into NIH Research Initiatives, to facilitate query tool user experience. NIH Research Initiatives map to one or multiple Funding Opportunity Announcements.
  • Collection State
    The Collection State indicates whether the Collection is viewable and searchable. Collections can be either Private, Shared, or an Ongoing Study. A Collection that is shared does not necessarily have shared data as the Collection State and state of data are independent of each other. This field can be edited by Collection users with Administrative Privileges and the Program Officer as listed in eRA (for NIH funded grants). Changes must be saved by clicking the Save button at the bottom of the page.
  • Supporting Documentation
    Various documents and materials to enable efficient use of the data by investigators unfamiliar with the project and may include the research protocol, questionnaires, and study manuals.
  • Collection Title
    An editable field with the title of the Collection, which is often the title of the grant associated with the Collection.
  • Total Subjects Shared
    The total number of unique subjects for whom data have been shared and are available for users with permission to access data.
IDNameCreated DateStatusType
519Resting11/08/2016ApprovedfMRI
520Resting-Chicago11/10/2016ApprovedfMRI
521Resting - Hartford11/15/2016ApprovedfMRI
528Rest - eyes open11/30/2016ApprovedEEG
529ODDBALL12/01/2016ApprovedEEG
530GATING12/02/2016ApprovedEEG
556Rest - eyes closed12/20/2016ApprovedEEG
562Pro-Saccade12/28/2016ApprovedEye Tracking
565Antisaccade01/03/2017ApprovedEye Tracking
574Ramp Mask Ramp01/05/2017ApprovedEye Tracking
576Gaze Contingency Task01/06/2017ApprovedEye Tracking
603Polhemus01/18/2017ApprovedEEG
helpcenter.collection.experiments-tab

NDA Help Center

Collection - Experiments

The number of Experiments included is displayed in parentheses next to the tab name. You may download all experiments associated with the Collection via the Download button. You may view individual experiments by clicking the Experiment Name and add them to the Filter Cart via the Add to Cart button.

Collection Owners, Program Officers, and users with Submission or Administrative Privileges for the Collection may create or edit an Experiment.

Please note: The creation of an NDA Experiment does not necessarily mean that data collected, according to the defined Experiment, has been submitted or shared.

Frequently Asked Questions

  • Can an Experiment be associated with more than one Collection?

    Yes -see the “Copy” button in the bottom left when viewing an experiment. There are two actions that can be performed via this button:

    1. Copy the experiment with intent for modifications.
    2. Associate the experiment to the collection. No modifications can be made to the experiment.

Glossary

  • Experiment Status
    An Experiment must be Approved before data using the associated Experiment_ID may be uploaded.
  • Experiment ID
    The ID number automatically generated by NDA which must be included in the appropriate file when uploading data to link the Experiment Definition to the subject record.

Collection Owners and those with Collection Administrator permission, may edit a collection. The following is currently available for Edit on this page:

Shared Data

Data structures with the number of subjects submitted and shared are provided.

Akiskal Temperament Scale Clinical Assessments 1314
Barratt Impulsivity Scale Clinical Assessments 2160
Brief Assessment of Cognition Clinical Assessments 1926
Clinical Trials: Inclusion/Exclusion Criteria Clinical Assessments 2415
Demographics Data Clinical Assessments 2415
EEG Subject Files Imaging 1532
Eye Tracking Subject-Experiment Imaging 1499
Family History Form Clinical Assessments 2230
Hollingshead Socioeconomic Rating Scale Clinical Assessments 2318
Image Imaging 1098
Lethality Scale Clinical Assessments 359
Medications Clinical Assessments 1713
Montgomery-Asberg Depression Rating Scale Clinical Assessments 1083
Psychiatric Medical History Clinical Assessments 2415
Psychosocial Interview Clinical Assessments 2295
Research Subject Clinical Assessments 2415
Social Functioning Scale Clinical Assessments 2156
Structured Clinical Interview for the Positive and Negative Syndrome Scale Clinical Assessments 967
Structured Interview for DSM IV Personality Clinical Assessments 1286
Wechsler Memory Scale, Third Edition (WMS-III) Clinical Assessments 1906
Wide Range Achievement Test 4 (WRAT4) Clinical Assessments 2167
Young Mania Rating Scale Clinical Assessments 1070
helpcenter.collection.shared-data-tab

NDA Help Center

Collection - Shared Data

This tab provides a quick overview of the Data Structure title, Data Type, and Number of Subjects that are currently Shared for the Collection. The information presented in this tab is automatically generated by NDA and cannot be edited. If no information is visible on this tab, this would indicate the Collection does not have shared data or the data is private.

The shared data is available to other researchers who have permission to access data in the Collection's designated Permission Group(s). Use the Download button to get all shared data from the Collection to the Filter Cart.

Frequently Asked Questions

  • How will I know if another researcher uses data that I shared through the NIMH Data Archive (NDA)?
    To see what data your project have submitted are being used by a study, simply go the Associated Studies tab of your collection. Alternatively, you may review an NDA Study Attribution Report available on the General tab.
  • Can I get a supplement to share data from a completed research project?
    Often it becomes more difficult to organize and format data electronically after the project has been completed and the information needed to create a GUID may not be available; however, you may still contact a program staff member at the appropriate funding institution for more information.
  • Can I get a supplement to share data from a research project that is still ongoing?
    Unlike completed projects where researchers may not have the information needed to create a GUID and/or where the effort needed to organize and format data becomes prohibitive, ongoing projects have more of an opportunity to overcome these challenges. Please contact a program staff member at the appropriate funding institution for more information.

Glossary

  • Data Structure
    A defined organization and group of Data Elements to represent an electronic definition of a measure, assessment, questionnaire, or collection of data points. Data structures that have been defined in the NDA Data Dictionary are available at https://nda.nih.gov/general-query.html?q=query=data-structure
  • Data Type
    A grouping of data by similar characteristics such as Clinical Assessments, Omics, or Neurosignal data.
  • Shared
    The term 'Shared' generally means available to others; however, there are some slightly different meanings based on what is Shared. A Shared NDA Collection or NDA Study is viewable and searchable publicly regardless of the user's role or whether the user has an NDA account. A Shared Collection or NDA Study does not necessarily mean that data submitted to the Collection or used in the NDA Study have been shared as this is independently determined. Data are shared according the schedule defined in a Collection's Data Expected Tab and/or in accordance with data sharing expectations in the NDA Data Sharing Terms and Conditions. Additionally, Supporting Documentation uploaded to a Collection may be shared independent of whether data are shared, but will only be viewable and accessible if the Collection is Shared.

Collection Owners and those with Collection Administrator permission, may edit a collection. The following is currently available for Edit on this page:

Publications

Publications relevant to NDA data are listed below. Most displayed publications have been associated with the grant within Pubmed. Use the "+ New Publication" button to add new publications. Publications relevant/not relevant to data expected are categorized. Relevant publications are then linked to the underlying data by selecting the Create Study link. Study provides the ability to define cohorts, assign subjects, define outcome measures and lists the study type, data analysis and results. Analyzed data and results are expected in this way.

PubMed IDStudyTitleJournalAuthorsDateStatus
35260788Create StudyA subtype of institutionalized patients with schizophrenia characterized by pronounced subcortical and cognitive deficits.Neuropsychopharmacology : official publication of the American College of NeuropsychopharmacologyZhao, Qiannan; Cao, Hengyi; Zhang, Wenjing; Li, Siyi; Xiao, Yuan; Tamminga, Carol A; Keshavan, Matcheri S; Pearlson, Godfrey D; Clementz, Brett A; Gershon, Elliot S; Hill, Scot Kristian; Keedy, Sarah K; Ivleva, Elena I; Lencer, Rebekka; Sweeney, John A; Gong, Qiyong; Lui, SuMarch 8, 2022Not Determined
34887147Create StudyReal-time facial emotion recognition deficits across the psychosis spectrum: A B-SNIP Study.Schizophrenia researchRubin, Leah H; Han, Jiaxu; Coughlin, Jennifer M; Hill, S Kristian; Bishop, Jeffrey R; Tamminga, Carol A; Clementz, Brett A; Pearlson, Godfrey D; Keshavan, Matcheri S; Gershon, Elliot S; Heilman, Keri J; Porges, Stephen W; Sweeney, John A; Keedy, SarahMay 1, 2022Not Determined
34756932Create StudyImpact of polygenic risk for coronary artery disease and cardiovascular medication burden on cognitive impairment in psychotic disorders.Progress in neuro-psychopharmacology & biological psychiatryZhang, Lusi; Hill, Scot Kristian; Guo, Bin; Wu, Baolin; Alliey-Rodriguez, Ney; Eum, Seenae; Lizano, Paulo; Ivleva, Elena I; Reilly, James L; Keefe, Richard S E; Keedy, Sarah K; Tamminga, Carol A; Pearlson, Godfrey D; Clementz, Brett A; Keshavan, Matcheri S; Gershon, Elliot S; Sweeney, John A; Bishop, Jeffrey RMarch 8, 2022Not Determined
34554256Create StudyQuantifying Retinal Microvascular Morphology in Schizophrenia Using Swept-Source Optical Coherence Tomography Angiography.Schizophrenia bulletinBannai, Deepthi; Adhan, Iniya; Katz, Raviv; Kim, Leo A; Keshavan, Matcheri; Miller, John B; Lizano, PauloJanuary 21, 2022Not Determined
34508358Create StudySubtyping Schizophrenia Patients Based on Patterns of Structural Brain Alterations.Schizophrenia bulletinXiao, Yuan; Liao, Wei; Long, Zhiliang; Tao, Bo; Zhao, Qiannan; Luo, Chunyan; Tamminga, Carol A; Keshavan, Matcheri S; Pearlson, Godfrey D; Clementz, Brett A; Gershon, Elliot S; Ivleva, Elena I; Keedy, Sarah K; Biswal, Bharat B; Mechelli, Andrea; Lencer, Rebekka; Sweeney, John A; Lui, Su; Gong, QiyongJanuary 21, 2022Not Determined
34409449Create StudyPsychosis Biotypes: Replication and Validation from the B-SNIP Consortium.Schizophrenia bulletinClementz, Brett A; Parker, David A; Trotti, Rebekah L; McDowell, Jennifer E; Keedy, Sarah K; Keshavan, Matcheri S; Pearlson, Godfrey D; Gershon, Elliot S; Ivleva, Elena I; Huang, Ling-Yu; Hill, S Kristian; Sweeney, John A; Thomas, Olivia; Hudgens-Haney, Matthew; Gibbons, Robert D; Tamminga, Carol AJanuary 21, 2022Not Determined
34392106Create StudyDeficits in generalized cognitive ability, visual sensorimotor function, and inhibitory control represent discrete domains of neurobehavioral deficit in psychotic disorders.Schizophrenia researchEskridge, Courtney L M; Hochberger, William C; Kaseda, Erin T; Lencer, Rebekka; Reilly, James L; Keedy, Sarah K; Keefe, Richard S E; Pearlson, Godfrey D; Keshavan, Matcheri S; Tamminga, Carol A; Sweeney, John A; Hill, S KristianOctober 1, 2021Not Determined
34322947Create StudyImproving the predictive potential of diffusion MRI in schizophrenia using normative models-Towards subject-level classification.Human brain mappingElad, Doron; Cetin-Karayumak, Suheyla; Zhang, Fan; Cho, Kang Ik K; Lyall, Amanda E; Seitz-Holland, Johanna; Ben-Ari, Rami; Pearlson, Godfrey D; Tamminga, Carol A; Sweeney, John A; Clementz, Brett A; Schretlen, David J; Viher, Petra Verena; Stegmayer, Katharina; Walther, Sebastian; Lee, Jungsun; Crow, Tim J; James, Anthony; Voineskos, Aristotle N; Buchanan, Robert W; Szeszko, Philip R; Malhotra, Anil K; Keshavan, Matcheri S; Shenton, Martha E; Rathi, Yogesh; Bouix, Sylvain; Sochen, Nir; Kubicki, Marek R; Pasternak, OferOctober 1, 2021Not Determined
34315649Create StudyAn opportunity for primary prevention research in psychotic disorders.Schizophrenia researchGershon, Elliot S; Lee, S Hong; Zhou, Xuan; Sweeney, John A; Tamminga, Carol; Pearlson, Godfrey A; Clementz, Brett A; Keshavan, Matcheri S; Alliey-Rodriguez, Ney; Hudgens-Haney, Matthew; Keedy, Sarah K; Glahn, David C; Asif, Huma; Lencer, Rebekka; Hill, S KristianMay 1, 2022Not Determined
34254147Create StudyA Diagnosis and Biotype Comparison Across the Psychosis Spectrum: Investigating Volume and Shape Amygdala-Hippocampal Differences from the B-SNIP Study.Schizophrenia bulletinGuimond, Synthia; Gu, Feng; Shannon, Holly; Kelly, Sinead; Mike, Luke; Devenyi, Gabriel A; Chakravarty, M Mallar; Sweeney, John A; Pearlson, Godfrey; Clementz, Brett A; Tamminga, Carol; Keshavan, MatcheriOctober 21, 2021Not Determined
34145405Create StudyGenome-wide association study accounting for anticholinergic burden to examine cognitive dysfunction in psychotic disorders.Neuropsychopharmacology : official publication of the American College of NeuropsychopharmacologyEum, Seenae; Hill, S Kristian; Alliey-Rodriguez, Ney; Stevenson, James M; Rubin, Leah H; Lee, Adam M; Mills, Lauren J; Reilly, James L; Lencer, Rebekka; Keedy, Sarah K; Ivleva, Elena; Keefe, Richard S E; Pearlson, Godfrey D; Clementz, Brett A; Tamminga, Carol A; Keshavan, Matcheri S; Gershon, Elliot S; Sweeney, John A; Bishop, Jeffrey RSeptember 1, 2021Not Determined
33836922Create StudyDevelopment of a computerized adaptive diagnostic screening tool for psychosis.Schizophrenia researchGibbons, Robert D; Chattopadhyay, Ishanu; Meltzer, Herbert Y; Kane, John M; Guinart, DanielJuly 1, 2022Not Determined
33693883Create StudyBiomarker Profiles in Psychosis Risk Groups Within Unaffected Relatives Based on Familiality and Age.Schizophrenia bulletinTürközer, Halide Bilge; Ivleva, Elena I; Palka, Jayme; Clementz, Brett A; Shafee, Rebecca; Pearlson, Godfrey D; Sweeney, John A; Keshavan, Matcheri S; Gershon, Elliot S; Tamminga, Carol AJuly 8, 2021Not Determined
33676821Create StudyMapping relationships among schizophrenia, bipolar and schizoaffective disorders: A deep classification and clustering framework using fMRI time series.Schizophrenia researchYan, Weizheng; Zhao, Min; Fu, Zening; Pearlson, Godfrey D; Sui, Jing; Calhoun, Vince DJuly 1, 2022Not Determined
33622655Create StudySearching for Imaging Biomarkers of Psychotic Dysconnectivity.Biological psychiatry. Cognitive neuroscience and neuroimagingRodrigue, Amanda L; Mastrovito, Dana; Esteban, Oscar; Durnez, Joke; Koenis, Marinka M G; Janssen, Ronald; Alexander-Bloch, Aaron; Knowles, Emma M; Mathias, Samuel R; Mollon, Josephine; Pearlson, Godfrey D; Frangou, Sophia; Blangero, John; Poldrack, Russell A; Glahn, David CDecember 1, 2021Not Determined
33483689Create StudyElucidating the relationship between white matter structure, demographic, and clinical variables in schizophrenia-a multicenter harmonized diffusion tensor imaging study.Molecular psychiatrySeitz-Holland, Johanna; Cetin-Karayumak, Suheyla; Wojcik, Joanne D; Lyall, Amanda; Levitt, James; Shenton, Martha E; Pasternak, Ofer; Westin, Carl-Fredrik; Baxi, Madhura; Kelly, Sinead; Mesholam-Gately, Raquelle; Vangel, Mark; Pearlson, Godfrey; Tamminga, Carol A; Sweeney, John A; Clementz, Brett A; Schretlen, David; Viher, Petra Verena; Stegmayer, Katharina; Walther, Sebastian; Lee, Jungsun; Crow, Tim; James, Anthony; Voineskos, Aristotle; Buchanan, Robert W; Szeszko, Philip R; Malhotra, Anil K; Rathi, Yogesh; Keshavan, Matcheri; Kubicki, MarekSeptember 1, 2021Not Determined
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32674921Create StudyDistinguishing patterns of impairment on inhibitory control and general cognitive ability among bipolar with and without psychosis, schizophrenia, and schizoaffective disorder.Schizophrenia researchGotra, Milena Y; Hill, Scot K; Gershon, Elliot S; Tamminga, Carol A; Ivleva, Elena I; Pearlson, Godfrey D; Keshavan, Matcheri S; Clementz, Brett A; McDowell, Jennifer E; Buckley, Peter F; Sweeney, John A; Keedy, Sarah KSeptember 1, 2020Not Determined
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31759570Create StudyImaging-Based Subtyping for Psychiatric Syndromes.Neuroimaging clinics of North AmericaIvleva, Elena I; Turkozer, Halide B; Sweeney, John AFebruary 2020Not Determined
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31511636Create StudyWhite matter abnormalities across the lifespan of schizophrenia: a harmonized multi-site diffusion MRI study.Molecular psychiatryCetin-Karayumak, Suheyla; Di Biase, Maria A; Chunga, Natalia; Reid, Benjamin; Somes, Nathaniel; Lyall, Amanda E; Kelly, Sinead; Solgun, Bengisu; Pasternak, Ofer; Vangel, Mark; Pearlson, Godfrey; Tamminga, Carol; Sweeney, John A; Clementz, Brett; Schretlen, David; Viher, Petra Verena; Stegmayer, Katharina; Walther, Sebastian; Lee, Jungsun; Crow, Tim; James, Anthony; Voineskos, Aristotle; Buchanan, Robert W; Szeszko, Philip R; Malhotra, Anil K; Hegde, Rachal; McCarley, Robert; Keshavan, Matcheri; Shenton, Martha; Rathi, Yogesh; Kubicki, MarekDecember 2020Not Determined
31164007Create StudyAssociation of Choroid Plexus Enlargement With Cognitive, Inflammatory, and Structural Phenotypes Across the Psychosis Spectrum.The American journal of psychiatryLizano P, Lutz O, Ling G, Lee AM, Eum S, Bishop JR, Kelly S, Pasternak O, Clementz B, Pearlson G, Sweeney JA, Gershon E, Tamminga C, Keshavan MJuly 2019Not Determined
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29759822Create StudyMultivariate Relationships Between Cognition and Brain Anatomy Across the Psychosis Spectrum.Biological psychiatry. Cognitive neuroscience and neuroimagingRodrigue, Amanda L; McDowell, Jennifer E; Tandon, Neeraj; Keshavan, Matcheri S; Tamminga, Carol A; Pearlson, Godfrey D; Sweeney, John A; Gibbons, Robert D; Clementz, Brett ADecember 2018Not Determined
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29628270Create StudyAssociations between adolescent cannabis use and brain structure in psychosis.Psychiatry research. NeuroimagingAbush, Hila; Ghose, Subroto; Van Enkevort, Erin A; Clementz, Brett A; Pearlson, Godfrey D; Sweeney, John A; Keshavan, Matcheri S; Tamminga, Carol A; Ivleva, Elena IJune 2018Not Determined
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28985939Create StudyApplications of Resting State Functional MR Imaging to Neuropsychiatric Diseases.Neuroimaging clinics of North AmericaPearlson, Godfrey DavidNovember 2017Not Determined
28880494Create StudyClinical psychopathology in youth at familial high risk for psychosis.Early intervention in psychiatryShah, Jai L; Tandon, Neeraj; Montrose, Debra M; Mermon, Diana; Eack, Shaun M; Miewald, Jean; Keshavan, Matcheri SApril 2019Not Determined
28844436Create StudyPsychosis subgroups differ in intrinsic neural activity but not task-specific processing.Schizophrenia researchHudgens-Haney, Matthew E; Ethridge, Lauren E; McDowell, Jennifer E; Keedy, Sarah K; Pearlson, Godfrey D; Tamminga, Carol A; Keshavan, Matcheri S; Sweeney, John A; Clementz, Brett AMay 2018Not Determined
28545944Create StudyDeviation from expected cognitive ability across psychotic disorders.Schizophrenia researchHochberger, W C; Combs, T; Reilly, J L; Bishop, J R; Keefe, R S E; Clementz, B A; Keshavan, M S; Pearlson, G D; Tamminga, C A; Hill, S K; Sweeney, J AFebruary 2018Not Determined
28480992Create StudyInferring pathobiology from structural MRI in schizophrenia and bipolar disorder: Modeling head motion and neuroanatomical specificity.Human brain mappingYao, Nailin; Winkler, Anderson M; Barrett, Jennifer; Book, Gregory A; Beetham, Tamara; Horseman, Rachel; Leach, Olivia; Hodgson, Karen; Knowles, Emma E; Mathias, Samuel; Stevens, Michael C; Assaf, Michal; van Erp, Theo G M; Pearlson, Godfrey D; Glahn, David CAugust 2017Not Determined
28467520Create StudyTransdiagnostic Associations Between Functional Brain Network Integrity and Cognition.JAMA psychiatrySheffield, Julia M; Kandala, Sridhar; Tamminga, Carol A; Pearlson, Godfrey D; Keshavan, Matcheri S; Sweeney, John A; Clementz, Brett A; Lerman-Sinkoff, Dov B; Hill, S Kristian; Barch, Deanna MJune 2017Relevant
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28390849Create StudyCognitive burden of anticholinergic medications in psychotic disorders.Schizophrenia researchEum, Seenae; Hill, S Kristian; Rubin, Leah H; Carnahan, Ryan M; Reilly, James L; Ivleva, Elena I; Keedy, Sarah K; Tamminga, Carol A; Pearlson, Godfrey D; Clementz, Brett A; Gershon, Elliot S; Keshavan, Matcheri S; Keefe, Richard S E; Sweeney, John A; Bishop, Jeffrey RDecember 2017Not Determined
28294459Create StudyIdentifying dynamic functional connectivity biomarkers using GIG-ICA: Application to schizophrenia, schizoaffective disorder, and psychotic bipolar disorder.Human brain mappingDu, Yuhui; Pearlson, Godfrey D; Lin, Dongdong; Sui, Jing; Chen, Jiayu; Salman, Mustafa; Tamminga, Carol A; Ivleva, Elena I; Sweeney, John A; Keshavan, Matcheri S; Clementz, Brett A; Bustillo, Juan; Calhoun, Vince DMay 2017Not Determined
28029515Create StudyThe "polyenviromic risk score": Aggregating environmental risk factors predicts conversion to psychosis in familial high-risk subjects.Schizophrenia researchPadmanabhan, Jaya L; Shah, Jai L; Tandon, Neeraj; Keshavan, Matcheri SMarch 2017Not Determined
27872267Create StudyEndophenotypes, Epigenetics, Polygenicity and More: Irv Gottesman''s Dynamic Legacy.Schizophrenia bulletinBraff, David L; Tamminga, Carol AJanuary 2017Not Determined
27870395Create StudySex differences in associations of arginine vasopressin and oxytocin with resting-state functional brain connectivity.Journal of neuroscience researchRubin, Leah H; Yao, Li; Keedy, Sarah K; Reilly, James L; Bishop, Jeffrey R; Carter, C Sue; Pournajafi-Nazarloo, Hossein; Drogos, Lauren L; Tamminga, Carol A; Pearlson, Godfrey D; Keshavan, Matcheri S; Clementz, Brett A; Hill, Scot K; Liao, Wei; Ji, Gong-Jun; Lui, Su; Sweeney, John AJanuary 2017Not Relevant
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27755933Create StudyPsychoradiology: The Frontier of Neuroimaging in Psychiatry.RadiologyLui, Su; Zhou, Xiaohong Joe; Sweeney, John A; Gong, QiyongNovember 2016Not Relevant
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27519538Create StudyNew drug developments in psychosis: Challenges, opportunities and strategies.Progress in neurobiologyKeshavan, Matcheri S; Lawler, Ashley N; Nasrallah, Henry A; Tandon, RajivMay 2017Not Relevant
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27033329Create StudyCognitive Function in Individuals With Psychosis: Moderation by Adolescent Cannabis Use.Schizophrenia bulletinHanna, Rebecca C; Shalvoy, Alexandra; Cullum, C Munro; Ivleva, Elena I; Keshavan, Matcheri; Pearlson, Godfrey; Hill, S Kristian; Sweeney, John A; Tamminga, Carol A; Ghose, SubrotoNovember 2016Not Determined
26978185Create StudyPolygenic risk for type 2 diabetes mellitus among individuals with psychosis and their relatives.Journal of psychiatric researchPadmanabhan, Jaya L; Nanda, Pranav; Tandon, Neeraj; Mothi, Suraj S; Bolo, Nicolas; McCarroll, Steven; Clementz, Brett A; Gershon, Elliot S; Pearlson, Godfrey D; Sweeney, John A; Tamminga, Carol A; Keshavan, Matcheri SJune 2016Relevant
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26651391Create StudyIdentification of Distinct Psychosis Biotypes Using Brain-Based Biomarkers.The American journal of psychiatryClementz, Brett A; Sweeney, John A; Hamm, Jordan P; Ivleva, Elena I; Ethridge, Lauren E; Pearlson, Godfrey D; Keshavan, Matcheri S; Tamminga, Carol AApril 1, 2016Relevant
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26462502Create StudyMultivariate Genetic Correlates of the Auditory Paired Stimuli-Based P2 Event-Related Potential in the Psychosis Dimension From the BSNIP Study.Schizophrenia bulletinMokhtari, Mohammadreza; Narayanan, Balaji; Hamm, Jordan P; Soh, Pauline; Calhoun, Vince D; Ruaño, Gualberto; Kocherla, Mohan; Windemuth, Andreas; Clementz, Brett A; Tamminga, Carol A; Sweeney, John A; Keshavan, Matcheri S; Pearlson, Godfrey DMay 2016Relevant
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21288693Create StudyViewing the elephant from 200 feet: reconstructing the schizophrenia syndrome.Schizophrenia researchSweeney JAApril 2011Not Determined
20832248Create StudyRethinking the genetic basis for comorbidity of schizophrenia and type 2 diabetes.Schizophrenia researchLin PI, Shuldiner ARNovember 2010Not Determined
20691427Create StudyGenetic associations of brain structural networks in schizophrenia: a preliminary study.Biological psychiatryJagannathan, Kanchana; Calhoun, Vince D; Gelernter, Joel; Stevens, Michael C; Liu, Jingyu; Bolognani, Federico; Windemuth, Andreas; Ruaño, Gualberto; Assaf, Michal; Pearlson, Godfrey DOctober 1, 2010Relevant
20643934Create StudyA genetically modulated, intrinsic cingulate circuit supports human nicotine addiction.Proceedings of the National Academy of Sciences of the United States of AmericaHong, L Elliot; Hodgkinson, Colin A; Yang, Yihong; Sampath, Hemalatha; Ross, Thomas J; Buchholz, Brittany; Salmeron, Betty Jo; Srivastava, Vibhuti; Thaker, Gunvant K; Goldman, David; Stein, Elliot AJuly 2010Not Relevant
20147364Create StudyCortical kynurenine pathway metabolism: a novel target for cognitive enhancement in Schizophrenia.Schizophrenia bulletinWonodi I, Schwarcz RMarch 2010Not Determined
20114081Create StudyA CCA+ICA based model for multi-task brain imaging data fusion and its application to schizophrenia.NeuroImageSui, Jing; Adali, Tülay; Pearlson, Godfrey; Yang, Honghui; Sponheim, Scott R; White, Tonya; Calhoun, Vince DMay 15, 2010Relevant
19956400Create StudyConvergent approaches for defining functional imaging endophenotypes in schizophrenia.Frontiers in human neurosciencePearlson, Godfrey D; Calhoun, Vince D2009Not Relevant
19954751Create StudyGenetics and intermediate phenotypes of the schizophrenia--bipolar disorder boundary.Neuroscience and biobehavioral reviewsIvleva EI, Morris DW, Moates AF, Suppes T, Thaker GK, Tamminga CAMay 2010Not Determined
19948225Create StudyAnomalous neural circuit function in schizophrenia during a virtual Morris water task.NeuroImageFolley, Bradley S; Astur, Robert; Jagannathan, Kanchana; Calhoun, Vince D; Pearlson, Godfrey DFebruary 15, 2010Relevant
19738925Create StudyFunctional brain networks in schizophrenia: a review.Frontiers in human neuroscienceCalhoun, Vince D; Eichele, Tom; Pearlson, GodfreyJanuary 1, 2009Not Determined
19577651Create StudyAge-related cognitive gains are mediated by the effects of white matter development on brain network integration.NeuroImageStevens, Michael C; Skudlarski, Pawel; Pearlson, Godfrey D; Calhoun, Vince DDecember 2009Relevant
19457398Create StudyAn ICA-based method for the identification of optimal FMRI features and components using combined group-discriminative techniques.NeuroImageSui, Jing; Adali, Tülay; Pearlson, Godfrey D; Calhoun, Vince DMay 15, 2009Not Relevant
19450952Create StudyA comparison of neuropsychological dysfunction in first-episode psychosis patients with unipolar depression, bipolar disorder, and schizophrenia.Schizophrenia researchHill SK, Reilly JL, Harris MS, Rosen C, Marvin RW, Deleon O, Sweeney JASeptember 2009Not Determined
19285141Create StudyGenetic determinants of target and novelty-related event-related potentials in the auditory oddball response.NeuroImageLiu, Jingyu; Kiehl, Kent A; Pearlson, Godfrey; Perrone-Bizzozero, Nora I; Eichele, Tom; Calhoun, Vince DJuly 1, 2009Relevant
19223268Create StudyEndophenotypes in schizophrenia: a selective review.Schizophrenia researchAllen, Allyssa J; Griss, Mélina E; Folley, Bradley S; Hawkins, Keith A; Pearlson, Godfrey DApril 2009Not Relevant
19172631Create StudyA method for accurate group difference detection by constraining the mixing coefficients in an ICA framework.Human brain mappingSui, Jing; Adali, Tülay; Pearlson, Godfrey D; Clark, Vincent P; Calhoun, Vince DSeptember 2009Relevant
19054501Create StudyIs motion perception deficit in schizophrenia a consequence of eye-tracking abnormality?Biological psychiatryHong LE, Turano KA, O'Neill HB, Hao L, Wonodi I, McMahon RP, Thaker GKJune 15, 2009Not Determined
18827719Create StudyIntegrating functional brain neuroimaging and developmental cognitive neuroscience in child psychiatry research.Journal of the American Academy of Child and Adolescent PsychiatryPavuluri MN, Sweeney JANovember 2008Not Determined
18799287Create StudySchizophrenia, "just the facts": what we know in 2008 Part 3: neurobiology.Schizophrenia researchKeshavan MS, Tandon R, Boutros NN, Nasrallah HADecember 2008Not Relevant
18762587Create StudySensory gating endophenotype based on its neural oscillatory pattern and heritability estimate.Archives of general psychiatryHong LE, Summerfelt A, Mitchell BD, McMahon RP, Wonodi I, Buchanan RW, Thaker GKSeptember 2008Not Determined
18515820Create StudyComparing genes and phenomenology in the major psychoses: schizophrenia and bipolar 1 disorder.Schizophrenia bulletinIvleva E, Thaker G, Tamminga CAJuly 2008Not Determined
18502737Create StudyNeurophysiological endophenotypes across bipolar and schizophrenia psychosis.Schizophrenia bulletinThaker GKJuly 2008Not Determined
18448479Create StudyNeurocognitive allied phenotypes for schizophrenia and bipolar disorder.Schizophrenia bulletinHill SK, Harris MS, Herbener ES, Pavuluri M, Sweeney JAJuly 2008Not Determined
18033774Create StudySchizophrenia, psychiatric genetics, and Darwinian psychiatry: an evolutionary framework.Schizophrenia bulletinPearlson GD, Folley BSJuly 2008Not Relevant
helpcenter.collection.publications-tab

NDA Help Center

Collection - Publications

The number of Publications is displayed in parentheses next to the tab name. Clicking on any of the Publication Titles will open the Publication in a new internet browsing tab.

Collection Owners, Program Officers, and users with Submission or Administrative Privileges for the Collection may mark a publication as either Relevant or Not Relevant in the Status column.

Frequently Asked Questions

  • How can I determine if a publication is relevant?
    Publications are considered relevant to a collection when the data shared is directly related to the project or collection.
  • Where does the NDA get the publications?
    PubMed, an online library containing journals, articles, and medical research. Sponsored by NiH and National Library of Medicine (NLM).

Glossary

  • Create Study
    A link to the Create an NDA Study page that can be clicked to start creating an NDA Study with information such as the title, journal and authors automatically populated.
  • Not Determined Publication
    Indicates that the publication has not yet been reviewed and/or marked as Relevant or Not Relevant so it has not been determined whether an NDA Study is expected.
  • Not Relevant Publication
    A publication that is not based on data related to the aims of the grant/project associated with the Collection or not based on any data such as a review article and, therefore, an NDA Study is not expected to be created.
  • PubMed
    PubMed provides citation information for biomedical and life sciences publications and is managed by the U.S. National Institutes of Health's National Library of Medicine.
  • PubMed ID
    The PUBMed ID is the unique ID number for the publication as recorded in the PubMed database.
  • Relevant Publication
    A publication that is based on data related to the aims of the grant/project associated with the Collection and, therefore, an NDA Study is expected to be created.

Relevant Publications
PubMed IDStudyTitleJournalAuthorsDate
28467520Create StudyTransdiagnostic Associations Between Functional Brain Network Integrity and Cognition.JAMA psychiatrySheffield, Julia M; Kandala, Sridhar; Tamminga, Carol A; Pearlson, Godfrey D; Keshavan, Matcheri S; Sweeney, John A; Clementz, Brett A; Lerman-Sinkoff, Dov B; Hill, S Kristian; Barch, Deanna MJune 2017
28419491Create StudyIntrinsic neural activity differences among psychotic illnesses.PsychophysiologyHudgens-Haney, Matthew E; Ethridge, Lauren E; Knight, Justin B; McDowell, Jennifer E; Keedy, Sarah K; Pearlson, Godfrey D; Tamminga, Carol A; Keshavan, Matcheri S; Sweeney, John A; Clementz, Brett AAugust 2017
26978185Create StudyPolygenic risk for type 2 diabetes mellitus among individuals with psychosis and their relatives.Journal of psychiatric researchPadmanabhan, Jaya L; Nanda, Pranav; Tandon, Neeraj; Mothi, Suraj S; Bolo, Nicolas; McCarroll, Steven; Clementz, Brett A; Gershon, Elliot S; Pearlson, Godfrey D; Sweeney, John A; Tamminga, Carol A; Keshavan, Matcheri SJune 2016
26954565Create StudyCallosal Abnormalities Across the Psychosis Dimension: Bipolar Schizophrenia Network on Intermediate Phenotypes.Biological psychiatryFrancis, Alan N; Mothi, Suraj S; Mathew, Ian T; Tandon, Neeraj; Clementz, Brett; Pearlson, Godfrey D; Sweeney, John A; Tamminga, Carol A; Keshavan, Matcheri SOctober 15, 2016
26711526Create StudyImpulsivity across the psychosis spectrum: Correlates of cortical volume, suicidal history, and social and global function.Schizophrenia researchNanda P, Tandon N, Mathew IT, Padmanabhan JL, Clementz BA, Pearlson GD, Sweeney JA, Tamminga CA, Keshavan MSJanuary 2016
26651391Create StudyIdentification of Distinct Psychosis Biotypes Using Brain-Based Biomarkers.The American journal of psychiatryClementz, Brett A; Sweeney, John A; Hamm, Jordan P; Ivleva, Elena I; Ethridge, Lauren E; Pearlson, Godfrey D; Keshavan, Matcheri S; Tamminga, Carol AApril 1, 2016
26645510Create StudyUnitary construct of generalized cognitive ability underlying BACS performance across psychotic disorders and in their first-degree relatives.Schizophrenia researchHochberger, W C; Hill, S K; Nelson, C L M; Reilly, J L; Keefe, R S E; Pearlson, G D; Keshavan, M S; Tamminga, C A; Clementz, B A; Sweeney, J AJanuary 2016
26462502Create StudyMultivariate Genetic Correlates of the Auditory Paired Stimuli-Based P2 Event-Related Potential in the Psychosis Dimension From the BSNIP Study.Schizophrenia bulletinMokhtari, Mohammadreza; Narayanan, Balaji; Hamm, Jordan P; Soh, Pauline; Calhoun, Vince D; Ruaño, Gualberto; Kocherla, Mohan; Windemuth, Andreas; Clementz, Brett A; Tamminga, Carol A; Sweeney, John A; Keshavan, Matcheri S; Pearlson, Godfrey DMay 2016
25034764Create StudyPatients with schizophrenia demonstrate reduced cortical sensitivity to auditory oddball regularities.Schizophrenia researchBridwell, David A; Kiehl, Kent A; Pearlson, Godfrey D; Calhoun, Vince DSeptember 2014
25031221Create StudyMediodorsal and visual thalamic connectivity differ in schizophrenia and bipolar disorder with and without psychosis history.Schizophrenia bulletinAnticevic A, Yang G, Savic A, Murray JD, Cole MW, Repovs G, Pearlson GD, Glahn DCNovember 2014
24782562Create StudyVentral anterior cingulate connectivity distinguished nonpsychotic bipolar illness from psychotic bipolar disorder and schizophrenia.Schizophrenia bulletinAnticevic, Alan; Savic, Aleksandar; Repovs, Grega; Yang, Genevieve; McKay, D Reese; Sprooten, Emma; Knowles, Emma E; Krystal, John H; Pearlson, Godfrey D; Glahn, David CJanuary 2015
24247856Create StudyHippocampal volume reduction correlates with apathy in traumatic brain injury, but not schizophrenia.The Journal of neuropsychiatry and clinical neurosciencesTakayanagi Y, Gerner G, Takayanagi M, Rao V, Vannorsdall TD, Sawa A, Schretlen DJ, Cascella NG2013
24176576Create StudyAltered language network activity in young people at familial high-risk for schizophrenia.Schizophrenia researchThermenos, H W; Whitfield-Gabrieli, S; Seidman, L J; Kuperberg, G; Juelich, R J; Divatia, S; Riley, C; Jabbar, G A; Shenton, M E; Kubicki, M; Manschreck, T; Keshavan, M S; DeLisi, L EDecember 2013
23975275Create StudyProlonged hemodynamic response during incidental facial emotion processing in inter-episode bipolar I disorder.Brain imaging and behaviorRosenfeld, Ethan S; Pearlson, Godfrey D; Sweeney, John A; Tamminga, Carol A; Keshavan, Matcheri S; Nonterah, Camilla; Stevens, Michael CMarch 2014
23825317Create StudyCharacterizing thalamo-cortical disturbances in schizophrenia and bipolar illness.Cerebral cortex (New York, N.Y. : 1991)Anticevic, Alan; Cole, Michael W; Repovs, Grega; Murray, John D; Brumbaugh, Margaret S; Winkler, Anderson M; Savic, Aleksandar; Krystal, John H; Pearlson, Godfrey D; Glahn, David CDecember 2014
23791391Create StudyNeuropsychological functioning predicts community outcomes in affective and non-affective psychoses: a 6-month follow-up.Schizophrenia researchLewandowski KE, Cohen BM, Keshavan MS, Sperry SH, Ongür DAugust 2013
22892286Create StudyAlterations in brain structures underlying language function in young adults at high familial risk for schizophrenia.Schizophrenia researchFrancis, Alan N; Seidman, Larry J; Jabbar, Gul A; Mesholam-Gately, Raquelle; Thermenos, Heidi W; Juelich, Richard; Proal, Ashley C; Shenton, Martha; Kubicki, Marek; Mathew, Ian; Keshavan, Matcheri; Delisi, Lynn EOctober 2012
22669497Create StudyGenetic influences of resting state fMRI activity in language-related brain regions in healthy controls and schizophrenia patients: a pilot study.Brain imaging and behaviorJamadar, Sharna; Powers, Natalie R; Meda, Shashwath A; Calhoun, Vince D; Gelernter, Joel; Gruen, Jeffrey R; Pearlson, Godfrey DMarch 2013
22595508Create StudyPrefrontal cortical response to emotional faces in individuals with major depressive disorder in remission.Psychiatry researchKerestes R, Bhagwagar Z, Nathan PJ, Meda SA, Ladouceur CD, Maloney K, Matuskey D, Ruf B, Saricicek A, Wang F, Pearlson GD, Phillips ML, Blumberg HPApril 30, 2012
22180852Create StudySource-based morphometry analysis of group differences in fractional anisotropy in schizophrenia.Brain connectivityCaprihan, Arvind; Abbott, Chris; Yamamoto, Jeremy; Pearlson, Godfrey; Perrone-Bizzozero, Nora; Sui, Jing; Calhoun, Vince D2011
21733287Create StudyAbnormal prefrontal activity subserving attentional control of emotion in remitted depressed patients during a working memory task with emotional distracters.Psychological medicineKerestes, R; Ladouceur, C D; Meda, S; Nathan, P J; Blumberg, H P; Maloney, K; Ruf, B; Saricicek, A; Pearlson, G D; Bhagwagar, Z; Phillips, M LJanuary 2012
21640835Create StudyDiscriminating schizophrenia and bipolar disorder by fusing fMRI and DTI in a multimodal CCA+ joint ICA model.NeuroImageSui, Jing; Pearlson, Godfrey; Caprihan, Arvind; Adali, Tülay; Kiehl, Kent A; Liu, Jingyu; Yamamoto, Jeremy; Calhoun, Vince DAugust 1, 2011
21507613Create StudyGenetic influences of cortical gray matter in language-related regions in healthy controls and schizophrenia.Schizophrenia researchJamadar, S; Powers, N R; Meda, S A; Gelernter, J; Gruen, J R; Pearlson, G DJuly 2011
21331320Create StudyAberrant Processing of Deviant Stimuli in Schizophrenia Revealed by Fusion of FMRI and EEG Data.Acta neuropsychiatricaCalhoun, Vd; Wu, L; Kiehl, Ka; Eichele, T; Pearlson, GdJune 2010
20691427Create StudyGenetic associations of brain structural networks in schizophrenia: a preliminary study.Biological psychiatryJagannathan, Kanchana; Calhoun, Vince D; Gelernter, Joel; Stevens, Michael C; Liu, Jingyu; Bolognani, Federico; Windemuth, Andreas; Ruaño, Gualberto; Assaf, Michal; Pearlson, Godfrey DOctober 1, 2010
20114081Create StudyA CCA+ICA based model for multi-task brain imaging data fusion and its application to schizophrenia.NeuroImageSui, Jing; Adali, Tülay; Pearlson, Godfrey; Yang, Honghui; Sponheim, Scott R; White, Tonya; Calhoun, Vince DMay 15, 2010
19948225Create StudyAnomalous neural circuit function in schizophrenia during a virtual Morris water task.NeuroImageFolley, Bradley S; Astur, Robert; Jagannathan, Kanchana; Calhoun, Vince D; Pearlson, Godfrey DFebruary 15, 2010
19577651Create StudyAge-related cognitive gains are mediated by the effects of white matter development on brain network integration.NeuroImageStevens, Michael C; Skudlarski, Pawel; Pearlson, Godfrey D; Calhoun, Vince DDecember 2009
19285141Create StudyGenetic determinants of target and novelty-related event-related potentials in the auditory oddball response.NeuroImageLiu, Jingyu; Kiehl, Kent A; Pearlson, Godfrey; Perrone-Bizzozero, Nora I; Eichele, Tom; Calhoun, Vince DJuly 1, 2009
19172631Create StudyA method for accurate group difference detection by constraining the mixing coefficients in an ICA framework.Human brain mappingSui, Jing; Adali, Tülay; Pearlson, Godfrey D; Clark, Vincent P; Calhoun, Vince DSeptember 2009

You can use "Add New Data Expected" to add exsiting structures and create your project's list. However, this is also the method you can use to request new structures be created for your project. When adding the Data Expected item, if the structure already exists you can locate it and specify your dates and enrollment. To add a new structure and request it be defined in the Data Dictionary, select Upload Definition and attach the definition or material needed to create it, including manual, codebooks, forms, etc. If you have multiple files, please upload a zipped archive containing them all.

Expected dates should be selected based on the standard Data Sharing Regimen and are restricted to within date ranges based on the project start and end dates.

Data Expected
Data ExpectedTargeted EnrollmentInitial SubmissionSubjects SharedStatus
Mania Rating Scale info icon
1,07012/31/2016
1,070
Approved
Medical History info icon
2,41512/02/2012
2,415
Approved
Eye Tracking info icon
1,49901/31/2017
1,499
Approved
Demographics info icon
2,41512/31/2016
2,415
Approved
Positive and Negative Syndrome Scale (PANSS) info icon
96712/31/2016
967
Approved
Social Functioning Scale (SFS) info icon
2,15612/31/2016
2,156
Approved
Wechsler Memory Scale, Third Edition (WMS-III) info icon
1,90612/31/2016
1,906
Approved
Medications info icon
1,71312/31/2016
1,713
Approved
Research Subject and Pedigree info icon
2,41512/31/2016
2,415
Approved
Brief Assessment of Cognition info icon
1,92612/31/2016
1,926
Approved
Wide Range Achievement Test info icon
2,16712/31/2016
2,167
Approved
Structured Interview for DSM IV Personality info icon
1,28612/31/2016
1,286
Approved
Clinical Trials: Inclusion/Exclusion Criteria info icon
2,41512/31/2016
2,415
Approved
Imaging (Structural, fMRI, DTI, PET, microscopy) info icon
1,09801/31/2017
1,098
Approved
Family History Form info icon
2,23012/31/2016
2,230
Approved
Barratt Impulsivity Scale info icon
2,16012/31/2016
2,160
Approved
Psychosocial Interview info icon
2,29512/31/2016
2,295
Approved
EEG info icon
1,45901/31/2017
1,532
Approved
Montgomery-Asberg Depression Rating Scale info icon
1,08312/31/2016
1,083
Approved
Lethality Scale info icon
35912/31/2016
359
Approved
Akiskal Temperament Scale info icon
1,31412/31/2016
1,314
Approved
Structure not yet defined
No Status history for this Data Expected has been recorded yet
helpcenter.collection.data-expected-tab

NDA Help Center

Collection - Data Expected

The Data Expected tab displays the list of all data that NDA expects to receive in association with the Collection as defined by the contributing researcher, as well as the dates for the expected initial upload of the data, and when it is first expected to be shared, or with the research community. Above the primary table of Data Expected, any publications determined to be relevant to the data within the Collection are also displayed - members of the contributing research group can use these to define NDA Studies, connecting those papers to underlying data in NDA.

The tab is used both as a reference for those accessing shared data, providing information on what is expected and when it will be shared, and as the primary tracking mechanism for contributing projects. It is used by both contributing primary researchers, secondary researchers, and NIH Program and Grants Management staff.

Contributing researchers just getting started on their project will need to define this list by adding all of the items they are collecting under their grant and setting their schedule according to the NDA Data Sharing Regimen. If you fall into this category, you can begin by clicking "Add New Data Expected" and selecting which data structures you will be using, saving the page after each change, or requesting new structures by adding and naming a new item, providing any materials NDA Data Dictionary Curators can use to help define your structure. For more information see the tutorial on creating Data Expected.

If you are a contributing researcher creating this list for the first time, or making changes to the list as your project progress, please note the following:

  • Although items you add to the list and changes you make are displayed, they are not committed to the system until you Save the entire page using the "Save"" button at the bottom of your screen. Please Save after every change to ensure none of your work is lost.
  • If you attempt to add a new structure, the title you provide must be unique - if another structure exists with the same name your change will fail.
  • Adding a new structure to this list is the only way to request the creation of a new Data Dictionary definition.

Frequently Asked Questions

  • What is an NDA Data Structure?
    An NDA Data Structure is comprised of multiple Data Elements to make up an electronic definition of an assessment, measure, questionnaire, etc will have a corresponding Data Structure.
  • What is the NDA Data Dictionary?
    The NDA Data Dictionary is comprised of electronic definitions known as Data Structures.

Glossary

  • Analyzed Data
    Data specific to the primary aims of the research being conducted (e.g. outcome measures, other dependent variables, observations, laboratory results, analyzed images, volumetric data, etc.) including processed images.
  • Data Item
    Items listed on the Data Expected list in the Collection which may be an individual and discrete Data Structure, Data Structure Category, or Data Structure Group.
  • Data Structure
    A defined organization and group of Data Elements to represent an electronic definition of a measure, assessment, questionnaire, or collection of data points. Data structures that have been defined in the NDA Data Dictionary are available at https://nda.nih.gov/general-query.html?q=query=data-structure
  • Data Structure Category
    An NDA term describing the affiliation of a Data Structure to a Category, which may be disease/disorder or diagnosis related (Depression, ADHD, Psychosis), specific to data type (MRI, eye tracking, omics), or type of data (physical exam, IQ).
  • Data Structure Group
    A Data Item listed on the Data Expected tab of a Collection that indicates a group of Data Structures (e.g., ADOS or SCID) for which data may be submitted instead of a specific Data Structure identified by version, module, edition, etc. For example, the ADOS Data Structure Category includes every ADOS Data Structure such as ADOS Module 1, ADOS Module 2, ADOS Module 1 - 2nd Edition, etc. The SCID Data Structure Group includes every SCID Data Structure such as SCID Mania, SCID V Mania, SCID PTSD, SCID-V Diagnosis, and more.
  • Evaluated Data
    A new Data Structure category, Evaluated Data is analyzed data resulting from the use of computational pipelines in the Cloud and can be uploaded directly back to a miNDAR database. Evaluated Data is expected to be listed as a Data Item in the Collection's Data Expected Tab.
  • Imaging Data
    Imaging+ is an NDA term which encompasses all imaging related data including, but not limited to, images (DTI, MRI, PET, Structural, Spectroscopy, etc.) as well as neurosignal data (EEG, fMRI, MEG, EGG, eye tracking, etc.) and Evaluated Data.
  • Initial Share Date
    Initial Submission and Initial Share dates should be populated according to the NDA Data Sharing Terms and Conditions. Any modifications to these will go through the approval processes outlined above. Data will be shared with authorized users upon publication (via an NDA Study) or 1-2 years after the grant end date specified on the first Notice of Award, as defined in the applicable Data Sharing Terms and Conditions.
  • Initial Submission Date
    Initial Submission and Initial Share dates should be populated according to these NDA Data Sharing Terms and Conditions. Any modifications to these will go through the approval processes outlined above. Data for all subjects is not expected on the Initial Submission Date and modifications may be made as necessary based on the project's conduct.
  • Research Subject and Pedigree
    An NDA created Data Structure used to convey basic information about the subject such as demographics, pedigree (links family GUIDs), diagnosis/phenotype, and sample location that are critical to allow for easier querying of shared data.
  • Submission Cycle
    The NDA has two Submission Cycles per year - January 15 and July 15.
  • Submission Exemption
    An interface to notify NDA that data may not be submitted during the upcoming/current submission cycle.

Collection Owners and those with Collection Administrator permission, may edit a collection. The following is currently available for Edit on this page:

Associated Studies

Studies that have been defined using data from a Collection are important criteria to determine the value of data shared. The number of subjects column displays the counts from this Collection that are included in a Study, out of the total number of subjects in that study. The Data Use column represents whether or not the study is a primary analysis of the data or a secondary analysis. State indicates whether the study is private or shared with the research community.

Study NameAbstractCollection/Study SubjectsData UsageState
The Frequency of Symptom-Based Phenotypes of Mental Disorders is Long-TailedThe heterogeneity of symptoms among individuals diagnosed with the same mental disorder has been blamed to hinder research in mental health and the development of effective treatments. Although widely acknowledged as problematic, the characteristics of this heterogeneity are largely unknown. We assessed the frequency of symptom phenotypes across a variety of clinical and non-clinical populations and found a consistent, long-tailed distribution. This distribution represents a mixture of a few very commonly expressed phenotypes and the sum of many, each only rarely displayed ones. As a consequence, the non-normality of this distribution induces a systematic bias, affecting all research and treatments relying on a symptom-based definition of mental disorders. 967/5743Secondary AnalysisShared
Trajectories of Adult AgingEEG Trajectories of Aging. 2327/3461Secondary AnalysisPrivate
Reproducibility of neuroimaging studies of brain disorders with hundreds of participantsFinding reliable and reproducible effects is crucial for the progress of any scientific field. Key determinants in this pursuit are the quality of the used methodology, the number of participants in the study (the "sample size") and the magnitude of the effects that are studied (the "effect size"). In a recent publication, Marek et al. provide important insights into the magnitude of effect sizes in neuroimaging MRI research: brain-behaviour associations in the general population between neuroimaging features and measurements of normative behaviour such as cognitive performance and psychometric metrics are characterised by (very) weak effects. Consequently, Marek et al. conclude that large sample sizes of over 3,000 subjects are required to find reproducible effects. Besides studying brain correlates of normative cognitive behaviour, another central goal in neuroimaging is to study aspects of brain structure and function in disease conditions to develop markers for psychiatric and neurological disorders. Brain patterns related to disease are likely more pronounced than general brain-behaviour associations, consequently investigations of clinical populations may encounter larger effects than among the healthy population. Here, we show by means of a few simple simulation and empirical experiments that neuroimaging studies studying the biological underpinnings of brain disorders require hundreds -and not always thousands- of participants to be able to detect reproducible findings. 2440/2440Secondary AnalysisPrivate
Neural Correlates of Global and Specific Cognitive Deficits in SchizophreniaCognitive deficits are a core feature of schizophrenia, but the neural mechanisms that contribute to these characteristics are not fully understood. This study investigated whether volume of the dorsal lateral prefrontal cortex (DLPFC), hippocampus, and white matter were associated with impairment in specific cognitive domains, including executive functioning, working memory, verbal memory, verbal fluency, processing speed, versus global functioning. The multi-site data used in this study was collected from the Bipolar and Schizophrenia Network on Intermediate Phenotypes (B-SNIP), and consisted of 206 healthy controls and 247 individuals with either schizophrenia or schizoaffective disorder. The neuroimaging data was segmented based on the Destrieux atlas in FreeSurfer. Linear regression analyses revealed that DLPFC volume was positively associated with executive functioning and processing speed, but not with working memory or verbal memory. Hippocampal volume was positively associated with executive functioning, working memory, and verbal memory, but not with verbal fluency. White matter volume was positively associated with processing speed, but not verbal fluency. Volume of all three brain structures were also associated with global cognitive functioning. However, DLPFC, hippocampal, and white matter volume were significantly associated with executive functioning even when controlling for global cognition, identifying a specific relationship. These findings suggest that volume of the DLPFC, hippocampus, and white matter are associated with both the global cognitive deficit in schizophrenia and with executive functioning, but may not have specific relationships to other cognitive domains over and above the global deficit. 445/445Secondary AnalysisPrivate
A growth curve of the human eye from 0-20 yearsThis study involves the semi automatic segmentation of the eyes of pediatric subjects for volume measurements3/173Secondary AnalysisPrivate
* Data not on individual level
helpcenter.collection.associated-studies-tab

NDA Help Center

Collection - Associated Studies

Clicking on the Study Title will open the study details in a new internet browser tab. The Abstract is available for viewing, providing the background explanation of the study, as provided by the Collection Owner.

Primary v. Secondary Analysis: The Data Usage column will have one of these two choices. An associated study that is listed as being used for Primary Analysis indicates at least some and potentially all of the data used was originally collected by the creator of the NDA Study. Secondary Analysis indicates the Study owner was not involved in the collection of data, and may be used as supporting data.

Private v. Shared State: Studies that remain private indicate the associated study is only available to users who are able to access the collection. A shared study is accessible to the general public.

Frequently Asked Questions

  • How do I associate a study to my collection?
    Studies are associated to the Collection automatically when the data is defined in the Study.

Glossary

  • Associated Studies Tab
    A tab in a Collection that lists the NDA Studies that have been created using data from that Collection including both Primary and Secondary Analysis NDA Studies.
Edit