NIMH Data Archive - Data

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¹ Numbers reported are subjects by age

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Format should be in the following format: Activity Code, Institute Abbreviation, and Serial Number. Grant Type, Support Year, and Suffix should be excluded. For example, grant 1R01MH123456-01A1 should be entered R01MH123456

Collection - Use Existing Experiment

To associate an experiment to the current collection, just select an axperiment from the table below then click the associate experiment button to persist your changes (saving the collection is not required). Note that once an experiment has been associated to two or more collections, the experiment will not longer be editable.

The table search feature is case insensitive and targets the experiment id, experiment name and experiment type columns. The experiment id is searched only when the search term entered is a number, and filtered using a startsWith comparison. When the search term is not numeric the experiment name is used to filter the results.

Select	Experiment Id	Experiment Name	Experiment Type	Created On

24	HI-NGS_R1	Omics	02/16/2011
475	MB1-10 (CHOP)	Omics	06/07/2016
490	Illumina Infinium PsychArray BeadChip Assay	Omics	07/07/2016
501	PharmacoBOLD Resting State	fMRI	07/27/2016
506	PVPREF	Omics	08/05/2016
509	ABC-CT Resting v2	EEG	08/18/2016
13	Comparison of FI expression in Autistic and Neurotypical Homo Sapiens	Omics	12/28/2010
18	AGRE/Broad Affymetrix 5.0 Genotype Experiment	Omics	01/06/2011
22	Stitching PCR Sequencing	Omics	02/14/2011
26	ASD_Methylation	Omics	03/01/2011
29	Microarray family 03 (father, mother, sibling)	Omics	03/24/2011
37	Standard paired-end sequencing of BCRs	Omics	04/19/2011
38	Illumina Mate-Pair BCR sequencing	Omics	04/19/2011
39	Custom Jumping Libraries	Omics	04/19/2011
40	Custom CapBP	Omics	04/19/2011
41	Immunofluorescence	Omics	05/11/2011
43	Autism brain sample genotyping, Illumina	Omics	05/16/2011
47	ARRA Autism Sequencing Collaboration at Baylor. SOLiD 4 System	Omics	08/01/2011
53	AGRE Omni1-quad	Omics	10/11/2011
59	AGP genotyping	Omics	04/03/2012
60	Ultradeep 454 sequencing of synaptic genes from postmortem cerebella of individuals with ASD and neurotypical controls	Omics	06/23/2012
63	Microemulsion PCR and Targeted Resequencing for Variant Detection in ASD	Omics	07/20/2012
76	Whole Genome Sequencing in Autism Families	Omics	01/03/2013
519	Resting	fMRI	11/08/2016
90	Genotyped IAN Samples	Omics	07/09/2013
91	NJLAGS Axiom Genotyping Array	Omics	07/16/2013
93	AGP genotyping (CNV)	Omics	09/06/2013
106	Longitudinal Sleep Study. H20 200. Channel set 2	EEG	11/07/2013
107	Longitudinal Sleep Study. H20 200. Channel set 3	EEG	11/07/2013
108	Longitudinal Sleep Study. AURA 200	EEG	11/07/2013
105	Longitudinal Sleep Study. H20 200. Channel set 1	EEG	11/07/2013
109	Longitudinal Sleep Study. AURA 400	EEG	11/07/2013
116	Gene Expression Analysis WG-6	Omics	01/07/2014
131	Jeste Lab UCLA ACEii: Charlie Brown and Sesame Street - Project 1	Eye Tracking	02/27/2014
132	Jeste Lab UCLA ACEii: Animacy - Project 1	Eye Tracking	02/27/2014
133	Jeste Lab UCLA ACEii: Mom Stranger - Project 2	Eye Tracking	02/27/2014
134	Jeste Lab UCLA ACEii: Face Emotion - Project 3	Eye Tracking	02/27/2014
145	AGRE/FMR1_Illumina.JHU	Omics	04/14/2014
146	AGRE/MECP2_Sanger.JHU	Omics	04/14/2014
147	AGRE/MECP2_Junior.JHU	Omics	04/14/2014
151	Candidate Gene Identification in familial Autism	Omics	06/09/2014
152	NJLAGS Whole Genome Sequencing	Omics	07/01/2014
154	Math Autism Study - Vinod Menon	fMRI	07/15/2014
155	Resting	fMRI	07/25/2014
156	Speech	fMRI	07/25/2014
159	Emotion	fMRI	07/25/2014
160	syllable contrast	EEG	07/29/2014
167	School-age naturalistic stimuli	Eye Tracking	09/19/2014
44	AGRE/Broad Affymetrix 5.0 Genotype Experiment	Omics	06/27/2011
45	Exome Sequencing of 20 Sporadic Cases of Autism Spectrum Disorder	Omics	07/15/2011

Collection - Add Experiment

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To add an existing Data Structure, enter its title in the search bar. If you need to request changes, select the indicator "No, it requires changes to meet research needs" after selecting the Structure, and upload the file with the request changes specific to the selected Data Structure. Your file should follow the Request Changes Procedure. If the Data Structure does not exist, select "Request New Data Structure" and upload the appropriate zip file.

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Neurodevelopment and Psychosis in the 22q11.2 Deletion Syndrome #2414

General
Experiments (0)
Shared Data
Publications (112)
Data Expected (22)
Associated Studies (0)

Collection Title	Collection Investigators	Collection Description
Collection Title:	Neurodevelopment and Psychosis in the 22q11.2 Deletion Syndrome
Collection Investigators:	Carrie Bearden
Collection Description:	Schizophrenia and other psychotic disorders are highly disabling conditions with poorly understood pathophysiology. One of the central challenges in elucidating mechanisms of psychosis is its remarkable genetic and phenotypic heterogeneity. Taking a genetics first approach (i.e., ascertaining patients based on a known, homogeneous genetic etiology) may allow us to overcome the barriers posed by this complexity. 22q11.2 deletion syndrome (Velocardiofacial/DiGeorge syndrome; 22q11DS) is a particularly compelling model, as it represents the greatest known genetic risk factor for psychosis identified to date. As the deletion can be detected very early in development, it offers an extraordinary opportunity for prospective investigation of early biomarkers of psychosis, long before disease-related processes begin to unfold. In the current funding cycle we have elucidated key points of convergence between disturbances in cognition, neural circuitry and gene expression relevant to psychosis in this genetic risk model and in idiopathic psychosis. In this competitive renewal application we plan to continue to prospectively follow a large cohort of youth with 22q11DS (n=90) through the highest risk period for illness onset, and demographically comparable typically developing controls (n=45), in order to establish whether common mechanisms contribute to psychotic symptomatology in 22q11DS and in idiopathic psychosis. Our primary goals (building on our findings from the original funding period) are to elucidate biological pathways and brain biomarkers which may represent convergent mechanisms for disease evolution. Given new discoveries in clinical high risk populations implicating inflammatory and neurohormonal processes in brain changes associated with the development of psychosis, we have added novel measures to assess these domains. In particular, our aims are to: 1) Investigate baseline and progressive abnormalities in structural and functional brain biomarkers, with the prediction that changes in temporal gray matter and thalamo-cortical functional connectivity will predict worsening cognition, social function and increased psychotic symptoms over time; 2) Determine the role of inflammatory mechanisms and stress sensitivity in the evolution of psychotic symptoms, using assays of both peripheral and neural inflammation [i.e., a novel free water diffusion imaging paradigm which is strongly correlated with positron emission tomography (PET) indices of activated microglia] and cortisol at each timepoint; 3) Determine biological pathways associated with psychosis-relevant phenotypes, by investigating upstream regulatory processes of circulating inflammatory markers; and 4) Given the recent discovery that 22q11.2 duplications may be protective against schizophrenia, we will prospectively follow 30 patients with gain of function mutations in the identical locus in order to investigate gene dosage effects on neurobehavioral phenotypes. This work will advance understanding of the genetic and developmental mechanisms by which 22q11.2 haploin sufficiency disrupts brain structure and function and ultimately contributes to disease pathogenesis.
Data Repository:	NIMH Data Archive
Permission Group:
Collection Creation Date:	07/19/2016
Collection Phase:	Funding Completed
Collection Sub-Phase:	Close Out
Blinded Clinical Trial:	No
Total Funded Amount:	$1,941,879.00
Subjects Shared:	124

{"values":[]}

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Funding Sources:

Funding Source Name	Funding Source URL
NIH - Extramural	None

Supporting Documentation:

Grant Information:

Project Number	Project Title	Start Date	End Date	Planned Enrollment	Actual Enrollment	Organization	Funds Obligated
R01MH085953-06	Neurodevelopment and Psychosis in the 22q11.2 Deletion Syndrome	09/06/2016	05/31/2021	165	175	UNIVERSITY OF CALIFORNIA LOS ANGELES	$1,575,475.00
R21MH116473-01	Neurobiological basis of dysconnectivity in a genetic risk model of psychosis	09/25/2018	07/31/2022	70	70	UNIVERSITY OF CALIFORNIA LOS ANGELES	$366,404.00

Clinical Trials:

helpcenter.collection.general-tab

Collection - General Tab

Fields available for edit on the top portion of the page include:

Collection Title
Investigators
Collection Description
Collection Phase
Funding Source
Clinical Trials

Collection Phase: The current status of a research project submitting data to an NDA Collection, based on the timing of the award and/or the data that have been submitted.

Pre-Enrollment: The default entry made when the NDA Collection is created.
Enrolling: Data have been submitted to the NDA Collection or the NDA Data Expected initial submission date has been reached for at least one data structure category in the NDA Collection.
Data Analysis: Subject level data collection for the research project is completed and has been submitted to the NDA Collection. The NDA Collection owner or the NDA Help Desk may set this phase when they’ve confirmed data submission is complete and submitted subject counts match at least 90% of the target enrollment numbers in the NDA Data Expected. Data submission reminders will be turned off for the NDA Collection.
Funding Completed: The NIH grant award (or awards) associated with the NDA Collection has reached its end date. NDA Collections in Funding Completed phase are assigned a subphase to indicate the status of data submission.
- The Data Expected Subphase indicates that NDA expects more data will be submitted
- The Closeout Subphase indicates the data submission is complete.
- The Sharing Not Met Subphase indicates that data submission was not completed as expected.

Blinded Clinical Trial Status:

This status is set by a Collection Owner and indicates the research project is a double blinded clinical trial. When selected, the public view of Data Expected will show the Data Expected items and the Submission Dates, but the targeted enrollment and subjects submitted counts will not be displayed.
Targeted enrollment and subjects submitted counts are visible only to NDA Administrators and to the NDA Collection or as the NDA Collection Owner.
When an NDA Collection that is flagged Blinded Clinical Trial reaches the maximum data sharing date for that Data Repository (see https://nda.nih.gov/nda/sharing-regimen.html), the embargo on Data Expected information is released.

Funding Source

The organization(s) responsible for providing the funding is listed here.

Supporting Documentation

Users with Submission privileges, as well as Collection Owners, Program Officers, and those with Administrator privileges, may upload and attach supporting documentation. By default, supporting documentation is shared to the general public, however, the option is also available to limit this information to qualified researchers only.

Grant Information

Identifiable details are displayed about the Project of which the Collection was derived from. You may click in the Project Number to view a full report of the Project captured by the NIH.

Clinical Trials

Any data that is collected to support or further the research of clinical studies will be available here. Collection Owners and those with Administrator privileges may add new clinical trials.

Frequently Asked Questions

How does the NIMH Data Archive (NDA) determine which Permission Group data are submitted into?

During Collection creation, NDA staff determine the appropriate Permission Group based on the type of data to be submitted, the type of access that will be available to data access users, and the information provided by the Program Officer during grant award.
How do I know when a NDA Collection has been created?

When a Collection is created by NDA staff, an email notification will automatically be sent to the PI(s) of the grant(s) associated with the Collection to notify them.
Is a single grant number ever associated with more than one Collection?

The NDA system does not allow for a single grant to be associated with more than one Collection; therefore, a single grant will not be listed in the Grant Information section of a Collection for more than one Collection.
Why is there sometimes more than one grant included in a Collection?

In general, each Collection is associated with only one grant; however, multiple grants may be associated if the grant has multiple competing segments for the same grant number or if multiple different grants are all working on the same project and it makes sense to hold the data in one Collection (e.g., Cooperative Agreements).

Glossary

Administrator Privilege

A privilege provided to a user associated with an NDA Collection or NDA Study whereby that user can perform a full range of actions including providing privileges to other users.
Collection Owner

Generally, the Collection Owner is the contact PI listed on a grant. Only one NDA user is listed as the Collection owner. Most automated emails are primarily sent to the Collection Owner.
Collection Phase
The Collection Phase provides information on data submission as opposed to grant/project completion so while the Collection phase and grant/project phase may be closely related they are often different. Collection users with Administrative Privileges are encouraged to edit the Collection Phase. The Program Officer as listed in eRA (for NIH funded grants) may also edit this field. Changes must be saved by clicking the Save button at the bottom of the page. This field is sortable alphabetically in ascending or descending order. Collection Phase options include:
- Pre-Enrollment: A grant/project has started, but has not yet enrolled subjects.
- Enrolling: A grant/project has begun enrolling subjects. Data submission is likely ongoing at this point.
- Data Analysis: A grant/project has completed enrolling subjects and has completed all data submissions.
- Funding Completed: A grant/project has reached the project end date.
Collection Title

An editable field with the title of the Collection, which is often the title of the grant associated with the Collection.
Grant

Provides the grant number(s) for the grant(s) associated with the Collection. The field is a hyperlink so clicking on the Grant number will direct the user to the grant information in the NIH Research Portfolio Online Reporting Tools (RePORT) page.
Supporting Documentation

Various documents and materials to enable efficient use of the data by investigators unfamiliar with the project and may include the research protocol, questionnaires, and study manuals.
NIH Research Initiative

NDA Collections may be organized by scientific similarity into NIH Research Initiatives, to facilitate query tool user experience. NIH Research Initiatives map to one or multiple Funding Opportunity Announcements.
Permission Group

Access to shared record-level data in NDA is provisioned at the level of a Permission Group. NDA Permission Groups consist of one or multiple NDA Collections that contain data with the same subject consents.
Planned Enrollment

Number of human subject participants to be enrolled in an NIH-funded clinical research study. The data is provided in competing applications and annual progress reports.
Actual Enrollment

Number of human subjects enrolled in an NIH-funded clinical research study. The data is provided in annual progress reports.
NDA Collection

A virtual container and organization structure for data and associated documentation from one grant or one large project/consortium. It contains tools for tracking data submission and allows investigators to define a wide array of other elements that provide context for the data, including all general information regarding the data and source project, experimental parameters used to collect any event-based data contained in the Collection, methods, and other supporting documentation. They also allow investigators to link underlying data to an NDA Study, defining populations and subpopulations specific to research aims.
Data Use Limitations

Data Use Limitations (DULs) describe the appropriate secondary use of a dataset and are based on the original informed consent of a research participant. NDA only accepts consent-based data use limitations defined by the NIH Office of Science Policy.
Total Subjects Shared

The total number of unique subjects for whom data have been shared and are available for users with permission to access data.

Contact NDA Help Desk

ID	Name	Created Date	Status	Type
No records found.

helpcenter.collection.experiments-tab

Collection - Experiments

The number of Experiments included is displayed in parentheses next to the tab name. You may download all experiments associated with the Collection via the Download button. You may view individual experiments by clicking the Experiment Name and add them to the Filter Cart via the Add to Cart button.

Collection Owners, Program Officers, and users with Submission or Administrative Privileges for the Collection may create or edit an Experiment.

Please note: The creation of an NDA Experiment does not necessarily mean that data collected, according to the defined Experiment, has been submitted or shared.

Frequently Asked Questions

Can an Experiment be associated with more than one Collection?
Yes -see the “Copy” button in the bottom left when viewing an experiment. There are two actions that can be performed via this button:
1. Copy the experiment with intent for modifications.
2. Associate the experiment to the collection. No modifications can be made to the experiment.

Glossary

Experiment Status

An Experiment must be Approved before data using the associated Experiment_ID may be uploaded.
Experiment ID

The ID number automatically generated by NDA which must be included in the appropriate file when uploading data to link the Experiment Definition to the subject record.

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Shared Data:

Title	Type	Number of Subjects
Adult ADHD Self-Report Scale Screener	Clinical Assessments	37
BRIEF-Parent	Clinical Assessments	70
Barratt Impulsivity Scale	Clinical Assessments	20
Brief Psychiatric Rating Scale	Clinical Assessments	79
Child Behavior Checklist (CBCL) 6-18	Clinical Assessments	20
Daily Stress Inventory	Clinical Assessments	20
Global Functioning Scales	Clinical Assessments	1
Prodromal Questionnaire	Clinical Assessments	2
Repetitive Behavior Scale - Revised (RBS-R)	Clinical Assessments	20
Repetitive Behavior Scales - Early Childhood Supplement	Clinical Assessments	65
Risk Beliefs Questionnaire	Clinical Assessments	20
Screen for Child Anxiety Related Disorders (SCARED), Parent/Child	Clinical Assessments	71
Sensory Profile Adult	Clinical Assessments	20
Sensory Profile Short	Clinical Assessments	71
Social Communication Questionnaire (SCQ) - Current Form	Clinical Assessments	20
Social Responsiveness Scale (SRS)	Clinical Assessments	94
Social Responsiveness Scale (SRS) - Adult/Self Version	Clinical Assessments	65
Structured Interview for Prodromal Syndromes/Scale of Prodromal Symptoms	Clinical Assessments	95
Tanner Sexual Maturity Scale	Clinical Assessments	20
Youth Self Report	Clinical Assessments	38

helpcenter.collection.shared-data-tab

Collection - Shared Data

This tab provides a quick overview of the Data Structure title, Data Type, and Number of Subjects that are currently Shared for the Collection. The information presented in this tab is automatically generated by NDA and cannot be edited. If no information is visible on this tab, this would indicate the Collection does not have shared data or the data is private.

The shared data is available to other researchers who have permission to access data in the Collection's designated Permission Group(s). Use the Download button to get all shared data from the Collection to the Filter Cart.

Frequently Asked Questions

How will I know if another researcher uses data that I shared through the NIMH Data Archive (NDA)?

To see what data your project have submitted are being used by a study, simply go the Associated Studies tab of your collection. Alternatively, you may review an NDA Study Attribution Report available on the General tab.
Can I get a supplement to share data from a completed research project?

Often it becomes more difficult to organize and format data electronically after the project has been completed and the information needed to create a GUID may not be available; however, you may still contact a program staff member at the appropriate funding institution for more information.
Can I get a supplement to share data from a research project that is still ongoing?

Unlike completed projects where researchers may not have the information needed to create a GUID and/or where the effort needed to organize and format data becomes prohibitive, ongoing projects have more of an opportunity to overcome these challenges. Please contact a program staff member at the appropriate funding institution for more information.

Glossary

Data Structure

A defined organization and group of Data Elements to represent an electronic definition of a measure, assessment, questionnaire, or collection of data points. Data structures that have been defined in the NDA Data Dictionary are available at https://nda.nih.gov/general-query.html?q=query=data-structure
Data Type

A grouping of data by similar characteristics such as Clinical Assessments, Omics, or Neurosignal data.
Shared

The term 'Shared' generally means available to others; however, there are some slightly different meanings based on what is Shared. A Shared NDA Study is viewable and searchable publicly regardless of the user's role or whether the user has an NDA account. A Shared NDA Study does not necessarily mean that data used in the NDA Study have been shared as this is independently determined. Data are shared according the schedule defined in a Collection's Data Expected Tab and/or in accordance with data sharing expectations in the NDA Data Sharing Terms and Conditions. Additionally, Supporting Documentation uploaded to a Collection may be shared independent of whether data are shared.

Contact NDA Help Desk

Collection Owners and those with Collection Administrator permission, may edit a collection. The following is currently available for Edit on this page:

Publications

Publications relevant to NDA data are listed below. Most displayed publications have been associated with the grant within Pubmed. Use the "+ New Publication" button to add new publications. Publications relevant/not relevant to data expected are categorized. Relevant publications are then linked to the underlying data by selecting the Create Study link. Study provides the ability to define cohorts, assign subjects, define outcome measures and lists the study type, data analysis and results. Analyzed data and results are expected in this way.

PubMed ID	Study	Title	Journal	Authors	Date	Status
38585897	Create Study	Synaptic-dependent developmental dysconnectivity in 22q11.2 deletion syndrome.	bioRxiv : the preprint server for biology	Alvino, F G; Gini, S; Minetti, A; Pagani, M; Sastre-Yagüe, D; Barsotti, N; De Guzman, E; Schleifer, C; Stuefer, A; Kushan, L; Montani, C; Galbusera, A; Papaleo, F; Lombardo, M V; Pasqualetti, M; Bearden, C E; Gozzi, A	April 3, 2024	Not Determined
38531844	Create Study	Using rare genetic mutations to revisit structural brain asymmetry.	Nature communications	Kopal, Jakub; Kumar, Kuldeep; Shafighi, Kimia; Saltoun, Karin; Modenato, Claudia; Moreau, Clara A; Huguet, Guillaume; Jean-Louis, Martineau; Martin, Charles-Olivier; Saci, Zohra; Younis, Nadine; Douard, Elise; Jizi, Khadije; Beauchamp-Chatel, Alexis; Kushan, Leila; Silva, Ana I; van den Bree, Marianne B M; Linden, David E J; Owen, Michael J; Hall, Jeremy; Lippé, Sarah; Draganski, Bogdan; Sønderby, Ida E; Andreassen, Ole A; Glahn, David C; Thompson, Paul M; Bearden, Carrie E; Zatorre, Robert; Jacquemont, Sébastien; Bzdok, Danilo	March 26, 2024	Not Determined
38496470	Create Study	Functional MRI of imprinting memory: a new avenue for neurobiology of early learning.	Research square	Behroozi, Mehdi; Lorenzi, Elena; Tabrik, Sepideh; Tegenthoff, Martin; Gozzi, Alessandro; Güntürkün, Onur; Vallortigara, Giorgio	March 4, 2024	Not Determined
38431758	Create Study	Effects of gene dosage and development on subcortical nuclei volumes in individuals with 22q11.2 copy number variations.	Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology	Schleifer, Charles H; O'Hora, Kathleen P; Fung, Hoki; Xu, Jennifer; Robinson, Taylor-Ann; Wu, Angela S; Kushan-Wells, Leila; Lin, Amy; Ching, Christopher R K; Bearden, Carrie E	May 1, 2024	Not Determined
38382530	Create Study	Thalamocortical organoids enable in vitro modeling of 22q11.2 microdeletion associated with neuropsychiatric disorders.	Cell stem cell	Shin, David; Kim, Chang N; Ross, Jayden; Hennick, Kelsey M; Wu, Sih-Rong; Paranjape, Neha; Leonard, Rachel; Wang, Jerrick C; Keefe, Matthew G; Pavlovic, Bryan J; Donohue, Kevin C; Moreau, Clara; Wigdor, Emilie M; Larson, H Hanh; Allen, Denise E; Cadwell, Cathryn R; Bhaduri, Aparna; Popova, Galina; Bearden, Carrie E; Pollen, Alex A; Jacquemont, Sebastien; Sanders, Stephan J; Haussler, David; Wiita, Arun P; Frost, Nicholas A; Sohal, Vikaas S; Nowakowski, Tomasz J	March 7, 2024	Not Determined
38326324	Create Study	Macroscale coupling between structural and effective connectivity in the mouse brain.	Scientific reports	Benozzo, Danilo; Baron, Giorgia; Coletta, Ludovico; Chiuso, Alessandro; Gozzi, Alessandro; Bertoldo, Alessandra	February 7, 2024	Not Determined
38234766	Create Study	Neurocognitive Profiles of 22q11.2 and 16p11.2 Deletions and Duplications.	Research square	Gur, Ruben; Bearden, Carrie; Jacquemont, Sébastien; Jizi, Khadije; Amelsvoort van, Therese; van den Bree, Marianne; Vorstman, Jacob; Sebat, Jonathan; Ruparel, Kosha; Gallagher, Robert; Swillen, Ann; McClellan, Emily; White, Lauren; Crowley, Terrence; Giunta, Victoria; Kushan, Leila; O'Hora, Kathleen; Verbesselt, Jente; Vandensande, Ans; Vingerhoets, Claudia; van Haelst, Mieke; Hall, Jessica; Harwood, Janet; Chawner, Samuel; Patel, Nishi; Palad, Katrina; Hong, Oanh; Guevara, James; Martin, Charles-Olivier; Bélanger, Anne-Marie; Scherer, Stephen; Bassett, Anne; McDonald-McGinn, Donna; Gur, Raquel	December 29, 2023	Not Determined
38224541	Create Study	Source-based morphometry reveals structural brain pattern abnormalities in 22q11.2 deletion syndrome.	Human brain mapping	Ge, Ruiyang; Ching, Christopher R K; Bassett, Anne S; Kushan, Leila; Antshel, Kevin M; van Amelsvoort, Therese; Bakker, Geor; Butcher, Nancy J; Campbell, Linda E; Chow, Eva W C; Craig, Michael; Crossley, Nicolas A; Cunningham, Adam; Daly, Eileen; Doherty, Joanne L; Durdle, Courtney A; Emanuel, Beverly S; Fiksinski, Ania; Forsyth, Jennifer K; Fremont, Wanda; Goodrich-Hunsaker, Naomi J; Gudbrandsen, Maria; Gur, Raquel E; Jalbrzikowski, Maria; Kates, Wendy R; Lin, Amy; Linden, David E J; McCabe, Kathryn L; McDonald-McGinn, Donna; Moss, Hayley; Murphy, Declan G; Murphy, Kieran C; Owen, Michael J; Villalon-Reina, Julio E; Repetto, Gabriela M; Roalf, David R; Ruparel, Kosha; Schmitt, J Eric; Schuite-Koops, Sanne; Angkustsiri, Kathleen; Sun, Daqiang; Vajdi, Ariana; van den Bree, Marianne; Vorstman, Jacob; Thompson, Paul M; Vila-Rodriguez, Fidel; Bearden, Carrie E	January 1, 2024	Not Determined
38081838	Create Study	Evidence for increased parallel information transmission in human brain networks compared to macaques and male mice.	Nature communications	Griffa, Alessandra; Mach, Mathieu; Dedelley, Julien; Gutierrez-Barragan, Daniel; Gozzi, Alessandro; Allali, Gilles; Grandjean, Joanes; Van De Ville, Dimitri; Amico, Enrico	December 11, 2023	Not Determined
37997544	Create Study	Distinct neurocognitive profiles and clinical phenotypes associated with copy number variation at the 22q11.2 locus.	Autism research : official journal of the International Society for Autism Research	O'Hora, Kathleen P; Kushan-Wells, Leila; Schleifer, Charles H; Cruz, Shayne; Hoftman, Gil D; Jalbrzikowski, Maria; Gur, Raquel E; Gur, Ruben C; Bearden, Carrie E	December 1, 2023	Not Determined
37961662	Create Study	Effects of Gene Dosage and Development on Subcortical Nuclei Volumes in Individuals with 22q11.2 Copy Number Variations.	bioRxiv : the preprint server for biology	Schleifer, Charles H; O'Hora, Kathleen P; Fung, Hoki; Xu, Jennifer; Robinson, Taylor-Ann; Wu, Angela S; Kushan-Wells, Leila; Lin, Amy; Ching, Christopher R K; Bearden, Carrie E	November 1, 2023	Not Determined
37721640	Create Study	Sleep in 22q11.2 Deletion Syndrome: Current Findings, Challenges, and Future Directions.	Current psychiatry reports	O'Hora, Kathleen P; Schleifer, Charles H; Bearden, Carrie E	October 1, 2023	Not Determined
37718159	Create Study	Microglia complement signaling promotes neuronal elimination and normal brain functional connectivity.	Cerebral cortex (New York, N.Y. : 1991)	Deivasigamani, Senthilkumar; Miteva, Mariya T; Natale, Silvia; Gutierrez-Barragan, Daniel; Basilico, Bernadette; Di Angelantonio, Silvia; Weinhard, Laetitia; Molotkov, Dmitry; Deb, Sukrita; Pape, Constantin; Bolasco, Giulia; Galbusera, Alberto; Asari, Hiroki; Gozzi, Alessandro; Ragozzino, Davide; Gross, Cornelius T	October 14, 2023	Not Determined
37709253	Create Study	Longitudinal Development of Thalamocortical Functional Connectivity in 22q11.2 Deletion Syndrome.	Biological psychiatry. Cognitive neuroscience and neuroimaging	Schleifer, Charles H; O'Hora, Kathleen P; Jalbrzikowski, Maria; Bondy, Elizabeth; Kushan-Wells, Leila; Lin, Amy; Uddin, Lucina Q; Bearden, Carrie E	February 1, 2024	Not Determined
37661008	Create Study	Beyond the Global Brain Differences: Intraindividual Variability Differences in 1q21.1 Distal and 15q11.2 BP1-BP2 Deletion Carriers.	Biological psychiatry	Boen, Rune; Kaufmann, Tobias; van der Meer, Dennis; Frei, Oleksandr; Agartz, Ingrid; Ames, David; Andersson, Micael; Armstrong, Nicola J; Artiges, Eric; Atkins, Joshua R; Bauer, Jochen; Benedetti, Francesco; Boomsma, Dorret I; Brodaty, Henry; Brosch, Katharina; Buckner, Randy L; Cairns, Murray J; Calhoun, Vince; Caspers, Svenja; Cichon, Sven; Corvin, Aiden P; Crespo-Facorro, Benedicto; Dannlowski, Udo; David, Friederike S; de Geus, Eco J C; de Zubicaray, Greig I; Desrivières, Sylvane; Doherty, Joanne L; Donohoe, Gary; Ehrlich, Stefan; Eising, Else; Espeseth, Thomas; Fisher, Simon E; Forstner, Andreas J; Fortaner-Uyà, Lidia; Frouin, Vincent; Fukunaga, Masaki; Ge, Tian; Glahn, David C; Goltermann, Janik; Grabe, Hans J; Green, Melissa J; Groenewold, Nynke A; Grotegerd, Dominik; Grøntvedt, Gøril Rolfseng; Hahn, Tim; Hashimoto, Ryota; Hehir-Kwa, Jayne Y; Henskens, Frans A; Holmes, Avram J; Håberg, Asta K; Haavik, Jan; Jacquemont, Sebastien; Jansen, Andreas; Jockwitz, Christiane; Jönsson, Erik G; Kikuchi, Masataka; Kircher, Tilo; Kumar, Kuldeep; Le Hellard, Stephanie; Leu, Costin; Linden, David E; Liu, Jingyu; Loughnan, Robert; Mather, Karen A; McMahon, Katie L; McRae, Allan F; Medland, Sarah E; Meinert, Susanne; Moreau, Clara A; Morris, Derek W; Mowry, Bryan J; Mühleisen, Thomas W; Nenadić, Igor; Nöthen, Markus M; Nyberg, Lars; Ophoff, Roel A; Owen, Michael J; Pantelis, Christos; Paolini, Marco; Paus, Tomas; Pausova, Zdenka; Persson, Karin; Quidé, Yann; Marques, Tiago Reis; Sachdev, Perminder S; Sando, Sigrid B; Schall, Ulrich; Scott, Rodney J; Selbæk, Geir; Shumskaya, Elena; Silva, Ana I; Sisodiya, Sanjay M; Stein, Frederike; Stein, Dan J; Straube, Benjamin; Streit, Fabian; Strike, Lachlan T; Teumer, Alexander; Teutenberg, Lea; Thalamuthu, Anbupalam; Tooney, Paul A; Tordesillas-Gutierrez, Diana; Trollor, Julian N; van 't Ent, Dennis; van den Bree, Marianne B M; van Haren, Neeltje E M; Vázquez-Bourgon, Javier; Völzke, Henry; Wen, Wei; Wittfeld, Katharina; Ching, Christopher R K; Westlye, Lars T; Thompson, Paul M; Bearden, Carrie E; Selmer, Kaja K; Alnæs, Dag; Andreassen, Ole A; Sønderby, Ida E; ENIGMA-CNV Working Group	January 15, 2024	Not Determined
37434504	Create Study	Subcortical Brain Alterations in Carriers of Genomic Copy Number Variants.	The American journal of psychiatry	Kumar, Kuldeep; Modenato, Claudia; Moreau, Clara; Ching, Christopher R K; Harvey, Annabelle; Martin-Brevet, Sandra; Huguet, Guillaume; Jean-Louis, Martineau; Douard, Elise; Martin, Charles-Olivier; Younis, Nadine; Tamer, Petra; Maillard, Anne M; Rodriguez-Herreros, Borja; Pain, Aurélie; 16p11.2 European Consortium, Simons Searchlight Consortium; Kushan, Leila; Isaev, Dmitry; Alpert, Kathryn; Ragothaman, Anjani; Turner, Jessica A; Wang, Lei; Ho, Tiffany C; Schmaal, Lianne; Silva, Ana I; van den Bree, Marianne B M; Linden, David E J; Owen, Michael J; Hall, Jeremy; Lippé, Sarah; Dumas, Guillaume; Draganski, Bogdan; Gutman, Boris A; Sønderby, Ida E; Andreassen, Ole A; Schultz, Laura M; Almasy, Laura; Glahn, David C; Bearden, Carrie E; Thompson, Paul M; Jacquemont, Sébastien	September 1, 2023	Not Determined
37292882	Create Study	Distinct Neurocognitive Profiles and Clinical Phenotypes Associated with Copy Number Variation at the 22q11.2 Locus.	medRxiv : the preprint server for health sciences	O'Hora, Kathleen P; Kushan-Wells, Leila; Hoftman, Gil D; Jalbrzikowski, Maria; Gur, Raquel C; Gur, Ruben; Bearden, Carrie E	May 16, 2023	Not Determined
37151981	Create Study	Neurobehavioral risk factors influence prevalence and severity of hazardous substance use in youth at genetic and clinical high risk for psychosis.	Frontiers in psychiatry	Amir, Carolyn M; Kapler, Simon; Hoftman, Gil D; Kushan, Leila; Zinberg, Jamie; Cadenhead, Kristin S; Kennedy, Leda; Cornblatt, Barbara A; Keshavan, Matcheri; Mathalon, Daniel H; Perkins, Diana O; Stone, William; Tsuang, Ming T; Walker, Elaine F; Woods, Scott W; Cannon, Tyrone D; Addington, Jean; Bearden, Carrie E	January 1, 2023	Not Determined
36973511	Create Study	A consensus protocol for functional connectivity analysis in the rat brain.	Nature neuroscience	Grandjean, Joanes; Desrosiers-Gregoire, Gabriel; Anckaerts, Cynthia; Angeles-Valdez, Diego; Ayad, Fadi; Barrière, David A; Blockx, Ines; Bortel, Aleksandra; Broadwater, Margaret; Cardoso, Beatriz M; Célestine, Marina; Chavez-Negrete, Jorge E; Choi, Sangcheon; Christiaen, Emma; Clavijo, Perrin; Colon-Perez, Luis; Cramer, Samuel; Daniele, Tolomeo; Dempsey, Elaine; Diao, Yujian; Doelemeyer, Arno; Dopfel, David; Dvořáková, Lenka; Falfán-Melgoza, Claudia; Fernandes, Francisca F; Fowler, Caitlin F; Fuentes-Ibañez, Antonio; Garin, Clément M; Gelderman, Eveline; Golden, Carla E M; Guo, Chao C G; Henckens, Marloes J A G; Hennessy, Lauren A; Herman, Peter; Hofwijks, Nita; Horien, Corey; Ionescu, Tudor M; Jones, Jolyon; Kaesser, Johannes; Kim, Eugene; Lambers, Henriette; Lazari, Alberto; Lee, Sung-Ho; Lillywhite, Amanda; Liu, Yikang; Liu, Yanyan Y; López-Castro, Alejandra; López-Gil, Xavier; Ma, Zilu; MacNicol, Eilidh; Madularu, Dan; Mandino, Francesca; Marciano, Sabina; McAuslan, Matthew J; McCunn, Patrick; McIntosh, Alison; Meng, Xianzong; Meyer-Baese, Lisa; Missault, Stephan; Moro, Federico; Naessens, Daphne M P; Nava-Gomez, Laura J; Nonaka, Hiroi; Ortiz, Juan J; Paasonen, Jaakko; Peeters, Lore M; Pereira, Mickaël; Perez, Pablo D; Pompilus, Marjory; Prior, Malcolm; Rakhmatullin, Rustam; Reimann, Henning M; Reinwald, Jonathan; Del Rio, Rodrigo Triana; Rivera-Olvera, Alejandro; Ruiz-Pérez, Daniel; Russo, Gabriele; Rutten, Tobias J; Ryoke, Rie; Sack, Markus; Salvan, Piergiorgio; Sanganahalli, Basavaraju G; Schroeter, Aileen; Seewoo, Bhedita J; Selingue, Erwan; Seuwen, Aline; Shi, Bowen; Sirmpilatze, Nikoloz; Smith, Joanna A B; Smith, Corrie; Sobczak, Filip; Stenroos, Petteri J; Straathof, Milou; Strobelt, Sandra; Sumiyoshi, Akira; Takahashi, Kengo; Torres-García, Maria E; Tudela, Raul; van den Berg, Monica; van der Marel, Kajo; van Hout, Aran T B; Vertullo, Roberta; Vidal, Benjamin; Vrooman, Roël M; Wang, Victora X; Wank, Isabel; Watson, David J G; Yin, Ting; Zhang, Yongzhi; Zurbruegg, Stefan; Achard, Sophie; Alcauter, Sarael; Auer, Dorothee P; Barbier, Emmanuel L; Baudewig, Jürgen; Beckmann, Christian F; Beckmann, Nicolau; Becq, Guillaume J P C; Blezer, Erwin L A; Bolbos, Radu; Boretius, Susann; Bouvard, Sandrine; Budinger, Eike; Buxbaum, Joseph D; Cash, Diana; Chapman, Victoria; Chuang, Kai-Hsiang; Ciobanu, Luisa; Coolen, Bram F; Dalley, Jeffrey W; Dhenain, Marc; Dijkhuizen, Rick M; Esteban, Oscar; Faber, Cornelius; Febo, Marcelo; Feindel, Kirk W; Forloni, Gianluigi; Fouquet, Jérémie; Garza-Villarreal, Eduardo A; Gass, Natalia; Glennon, Jeffrey C; Gozzi, Alessandro; Gröhn, Olli; Harkin, Andrew; Heerschap, Arend; Helluy, Xavier; Herfert, Kristina; Heuser, Arnd; Homberg, Judith R; Houwing, Danielle J; Hyder, Fahmeed; Ielacqua, Giovanna Diletta; Jelescu, Ileana O; Johansen-Berg, Heidi; Kaneko, Gen; Kawashima, Ryuta; Keilholz, Shella D; Keliris, Georgios A; Kelly, Clare; Kerskens, Christian; Khokhar, Jibran Y; Kind, Peter C; Langlois, Jean-Baptiste; Lerch, Jason P; López-Hidalgo, Monica A; Manahan-Vaughan, Denise; Marchand, Fabien; Mars, Rogier B; Marsella, Gerardo; Micotti, Edoardo; Muñoz-Moreno, Emma; Near, Jamie; Niendorf, Thoralf; Otte, Willem M; Pais-Roldán, Patricia; Pan, Wen-Ju; Prado-Alcalá, Roberto A; Quirarte, Gina L; Rodger, Jennifer; Rosenow, Tim; Sampaio-Baptista, Cassandra; Sartorius, Alexander; Sawiak, Stephen J; Scheenen, Tom W J; Shemesh, Noam; Shih, Yen-Yu Ian; Shmuel, Amir; Soria, Guadalupe; Stoop, Ron; Thompson, Garth J; Till, Sally M; Todd, Nick; Van Der Linden, Annemie; van der Toorn, Annette; van Tilborg, Geralda A F; Vanhov (see original citation for additional authors)	April 1, 2023	Not Determined
36865328	Create Study	Subcortical brain alterations in carriers of genomic copy number variants.	medRxiv : the preprint server for health sciences	Kumar, Kuldeep; Modenato, Claudia; Moreau, Clara; Ching, Christopher R K; Harvey, Annabelle; Martin-Brevet, Sandra; Huguet, Guillaume; Jean-Louis, Martineau; Douard, Elise; Martin, Charles-Olivier; Younis, Nadine; Tamer, Petra; Maillard, Anne M; Rodriguez-Herreros, Borja; Pain, Aurélie; Richetin, Sonia; 16p11.2 European Consortium, Simons Searchlight Consortium; Kushan, Leila; Isaev, Dmitry; Alpert, Kathryn; Ragothaman, Anjani; Turner, Jessica A; Wang, Lei; Ho, Tiffany C; Schmaal, Lianne; Silva, Ana I; van den Bree, Marianne B M; Linden, David E J; Owen, Michael J; Hall, Jeremy; Lippé, Sarah; Dumas, Guillaume; Draganski, Bogdan; Gutman, Boris A; Sønderby, Ida E; Andreassen, Ole A; Schultz, Laura; Almasy, Laura; Glahn, David C; Bearden, Carrie E; Thompson, Paul M; Jacquemont, Sébastien	February 22, 2023	Not Determined
36865122	Create Study	Macroscale coupling between structural and effective connectivity in the mouse brain.	bioRxiv : the preprint server for biology	Benozzo, Danilo; Baron, Giorgia; Coletta, Ludovico; Chiuso, Alessandro; Gozzi, Alessandro; Bertoldo, Alessandra	February 27, 2023	Not Determined
36864136	Create Study	Rare CNVs and phenome-wide profiling highlight brain structural divergence and phenotypical convergence.	Nature human behaviour	Kopal, Jakub; Kumar, Kuldeep; Saltoun, Karin; Modenato, Claudia; Moreau, Clara A; Martin-Brevet, Sandra; Huguet, Guillaume; Jean-Louis, Martineau; Martin, Charles-Olivier; Saci, Zohra; Younis, Nadine; Tamer, Petra; Douard, Elise; Maillard, Anne M; Rodriguez-Herreros, Borja; Pain, Aurèlie; Richetin, Sonia; Kushan, Leila; Silva, Ana I; van den Bree, Marianne B M; Linden, David E J; Owen, Michael J; Hall, Jeremy; Lippé, Sarah; Draganski, Bogdan; Sønderby, Ida E; Andreassen, Ole A; Glahn, David C; Thompson, Paul M; Bearden, Carrie E; Jacquemont, Sébastien; Bzdok, Danilo	June 1, 2023	Not Determined
36737483	Create Study	CDKL5 sculpts functional callosal connectivity to promote cognitive flexibility.	Molecular psychiatry	Awad, Patricia Nora; Zerbi, Valerio; Johnson-Venkatesh, Erin M; Damiani, Francesca; Pagani, Marco; Markicevic, Marija; Nickles, Sarah; Gozzi, Alessandro; Umemori, Hisashi; Fagiolini, Michela	February 3, 2023	Not Determined
36372570	Create Study	Genetic Heterogeneity Shapes Brain Connectivity in Psychiatry.	Biological psychiatry	Moreau, Clara A; Harvey, Annabelle; Kumar, Kuldeep; Huguet, Guillaume; Urchs, Sebastian G W; Douard, Elise A; Schultz, Laura M; Sharmarke, Hanad; Jizi, Khadije; Martin, Charles-Olivier; Younis, Nadine; Tamer, Petra; Rolland, Thomas; Martineau, Jean-Louis; Orban, Pierre; Silva, Ana Isabel; Hall, Jeremy; van den Bree, Marianne B M; Owen, Michael J; Linden, David E J; Labbe, Aurelie; Lippé, Sarah; Bearden, Carrie E; Almasy, Laura; Glahn, David C; Thompson, Paul M; Bourgeron, Thomas; Bellec, Pierre; Jacquemont, Sebastien	January 1, 2023	Not Determined
36192458	Create Study	A genetics-first approach to understanding autism and schizophrenia spectrum disorders: the 22q11.2 deletion syndrome.	Molecular psychiatry	Fiksinski, Ania M; Hoftman, Gil D; Vorstman, Jacob A S; Bearden, Carrie E	January 1, 2023	Not Determined
36059063	Create Study	Brain functional connectivity mirrors genetic pleiotropy in psychiatric conditions.	Brain : a journal of neurology	Moreau, Clara A; Kumar, Kuldeep; Harvey, Annabelle; Huguet, Guillaume; Urchs, Sebastian G W; Schultz, Laura M; Sharmarke, Hanad; Jizi, Khadije; Martin, Charles-Olivier; Younis, Nadine; Tamer, Petra; Martineau, Jean-Louis; Orban, Pierre; Silva, Ana Isabel; Hall, Jeremy; van den Bree, Marianne B M; Owen, Michael J; Linden, David E J; Lippé, Sarah; Bearden, Carrie E; Almasy, Laura; Glahn, David C; Thompson, Paul M; Bourgeron, Thomas; Bellec, Pierre; Jacquemont, Sebastien	April 19, 2023	Not Determined
35948562	Create Study	Local molecular and global connectomic contributions to cross-disorder cortical abnormalities.	Nature communications	Hansen, Justine Y; Shafiei, Golia; Vogel, Jacob W; Smart, Kelly; Bearden, Carrie E; Hoogman, Martine; Franke, Barbara; van Rooij, Daan; Buitelaar, Jan; McDonald, Carrie R; Sisodiya, Sanjay M; Schmaal, Lianne; Veltman, Dick J; van den Heuvel, Odile A; Stein, Dan J; van Erp, Theo G M; Ching, Christopher R K; Andreassen, Ole A; Hajek, Tomas; Opel, Nils; Modinos, Gemma; Aleman, André; van der Werf, Ysbrand; Jahanshad, Neda; Thomopoulos, Sophia I; Thompson, Paul M; Carson, Richard E; Dagher, Alain; Misic, Bratislav	August 10, 2022	Not Determined
35915065	Create Study	D-aspartate oxidase gene duplication induces social recognition memory deficit in mice and intellectual disabilities in humans.	Translational psychiatry	Lombardo, Barbara; Pagani, Marco; De Rosa, Arianna; Nunziato, Marcella; Migliarini, Sara; Garofalo, Martina; Terrile, Marta; D'Argenio, Valeria; Galbusera, Alberto; Nuzzo, Tommaso; Ranieri, Annaluisa; Vitale, Andrea; Leggiero, Eleonora; Di Maio, Anna; Barsotti, Noemi; Borello, Ugo; Napolitano, Francesco; Mandarino, Alessandra; Carotenuto, Marco; Heresco-Levy, Uriel; Pasqualetti, Massimo; Malatesta, Paolo; Gozzi, Alessandro; Errico, Francesco; Salvatore, Francesco; Pastore, Lucio; Usiello, Alessandro	August 1, 2022	Not Determined
35896619	Create Study	Longitudinal trajectories of cortical development in 22q11.2 copy number variants and typically developing controls.	Molecular psychiatry	Jalbrzikowski, Maria; Lin, Amy; Vajdi, Ariana; Grigoryan, Vardui; Kushan, Leila; Ching, Christopher R K; Schleifer, Charles; Hayes, Rebecca A; Chu, Stephanie A; Sugar, Catherine A; Forsyth, Jennifer K; Bearden, Carrie E	October 1, 2022	Not Determined
35820809	Create Study	Copy number variation at the 22q11.2 locus influences prevalence, severity, and psychiatric impact of sleep disturbance.	Journal of neurodevelopmental disorders	O'Hora, Kathleen P; Lin, Amy; Kushan-Wells, Leila; Bearden, Carrie E	July 10, 2022	Not Determined
35483565	Create Study	Somatosensory cortex hyperconnectivity and impaired whisker-dependent responses in Cntnap2-/- mice.	Neurobiology of disease	Balasco, Luigi; Pagani, Marco; Pangrazzi, Luca; Chelini, Gabriele; Viscido, Francesca; Chama, Alessandra Georgette Ciancone; Galbusera, Alberto; Provenzano, Giovanni; Gozzi, Alessandro; Bozzi, Yuri	July 1, 2022	Not Determined
35236119	Create Study	Genes To Mental Health (G2MH): A Framework to Map the Combined Effects of Rare and Common Variants on Dimensions of Cognition and Psychopathology.	The American journal of psychiatry	Jacquemont, Sébastien; Huguet, Guillaume; Klein, Marieke; Chawner, Samuel J R A; Donald, Kirsten A; van den Bree, Marianne B M; Sebat, Jonathan; Ledbetter, David H; Constantino, John N; Earl, Rachel K; McDonald-McGinn, Donna M; van Amelsvoort, Therese; Swillen, Ann; O'Donnell-Luria, Anne H; Glahn, David C; Almasy, Laura; Eichler, Evan E; Scherer, Stephen W; Robinson, Elise; Bassett, Anne S; Martin, Christa Lese; Finucane, Brenda; Vorstman, Jacob A S; Bearden, Carrie E; Gur, Raquel E; Genes to Mental Health Network	March 1, 2022	Not Determined
35217677	Create Study	Increased fMRI connectivity upon chemogenetic inhibition of the mouse prefrontal cortex.	Nature communications	Rocchi, Federico; Canella, Carola; Noei, Shahryar; Gutierrez-Barragan, Daniel; Coletta, Ludovico; Galbusera, Alberto; Stuefer, Alexia; Vassanelli, Stefano; Pasqualetti, Massimo; Iurilli, Giuliano; Panzeri, Stefano; Gozzi, Alessandro	February 25, 2022	Not Determined
35119167	Create Study	Cross disorder comparisons of brain structure in schizophrenia, bipolar disorder, major depressive disorder, and 22q11.2 deletion syndrome: A review of ENIGMA findings.	Psychiatry and clinical neurosciences	Cheon, Eun-Jin; Bearden, Carrie E; Sun, Daqiang; Ching, Christopher R K; Andreassen, Ole A; Schmaal, Lianne; Veltman, Dick J; Thomopoulos, Sophia I; Kochunov, Peter; Jahanshad, Neda; Thompson, Paul M; Turner, Jessica A; van Erp, Theo G M	May 1, 2022	Not Determined
34998465	Create Study	Unique spatiotemporal fMRI dynamics in the awake mouse brain.	Current biology : CB	Gutierrez-Barragan, Daniel; Singh, Neha Atulkumar; Alvino, Filomena Grazia; Coletta, Ludovico; Rocchi, Federico; De Guzman, Elizabeth; Galbusera, Alberto; Uboldi, Mauro; Panzeri, Stefano; Gozzi, Alessandro	February 7, 2022	Not Determined
34841284	Create Study	Transcriptomic profiling of whole blood in 22q11.2 reciprocal copy number variants reveals that cell proportion highly impacts gene expression.	Brain, behavior, & immunity - health	Lin, Amy; Forsyth, Jennifer K; Hoftman, Gil D; Kushan-Wells, Leila; Jalbrzikowski, Maria; Dokuru, Deepika; Coppola, Giovanni; Fiksinski, Ania; Zinkstok, Janneke; Vorstman, Jacob; Nachun, Daniel; Bearden, Carrie E	December 1, 2021	Not Determined
34791077	Create Study	Abnormal Whisker-Dependent Behaviors and Altered Cortico-Hippocampal Connectivity in Shank3b-/- Mice.	Cerebral cortex (New York, N.Y. : 1991)	Balasco, Luigi; Pagani, Marco; Pangrazzi, Luca; Chelini, Gabriele; Ciancone Chama, Alessandra Georgette; Shlosman, Evgenia; Mattioni, Lorenzo; Galbusera, Alberto; Iurilli, Giuliano; Provenzano, Giovanni; Gozzi, Alessandro; Bozzi, Yuri	July 12, 2022	Not Determined
34759270	Create Study	Opposing white matter microstructure abnormalities in 22q11.2 deletion and duplication carriers.	Translational psychiatry	Seitz-Holland, Johanna; Lyons, Monica; Kushan, Leila; Lin, Amy; Villalon-Reina, Julio E; Cho, Kang Ik Kevin; Zhang, Fan; Billah, Tashrif; Bouix, Sylvain; Kubicki, Marek; Bearden, Carrie E; Pasternak, Ofer	November 10, 2021	Not Determined
34620586	Create Study	Heterotopia in Individuals with 22q11.2 Deletion Syndrome.	AJNR. American journal of neuroradiology	Neuhaus, E; Hattingen, E; Breuer, S; Steidl, E; Polomac, N; Rosenow, F; Rüber, T; Herrmann, E; Ecker, C; Kushan, L; Lin, A; Vajdi, A; Bearden, C E; Jurcoane, A	November 1, 2021	Not Determined
34588607	Create Study	The prediction-error hypothesis of schizophrenia: new data point to circuit-specific changes in dopamine activity.	Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology	Millard, Samuel J; Bearden, Carrie E; Karlsgodt, Katherine H; Sharpe, Melissa J	February 1, 2022	Not Determined
34381171	Create Study	Brain mapping across 16 autism mouse models reveals a spectrum of functional connectivity subtypes.	Molecular psychiatry	Zerbi, V; Pagani, M; Markicevic, M; Matteoli, M; Pozzi, D; Fagiolini, M; Bozzi, Y; Galbusera, A; Scattoni, M L; Provenzano, G; Banerjee, A; Helmchen, F; Basson, M A; Ellegood, J; Lerch, J P; Rudin, M; Gozzi, A; Wenderoth, N	December 1, 2021	Not Determined
34342000	Create Study	Harnessing rare variants in neuropsychiatric and neurodevelopment disorders-a Keystone Symposia report.	Annals of the New York Academy of Sciences	Cable, Jennifer; Purcell, Ryan H; Robinson, Elise; Vorstman, Jacob A S; Chung, Wendy K; Constantino, John N; Sanders, Stephan J; Sahin, Mustafa; Dolmetsch, Ricardo E; Shah, Bina Maniar; Thurm, Audrey; Martin, Christa L; Bearden, Carrie E; Mulle, Jennifer G	December 1, 2021	Not Determined
34285187	Create Study	Effects of eight neuropsychiatric copy number variants on human brain structure.	Translational psychiatry	Modenato, Claudia; Kumar, Kuldeep; Moreau, Clara; Martin-Brevet, Sandra; Huguet, Guillaume; Schramm, Catherine; Jean-Louis, Martineau; Martin, Charles-Olivier; Younis, Nadine; Tamer, Petra; Douard, Elise; Thébault-Dagher, Fanny; Côté, Valérie; Charlebois, Audrey-Rose; Deguire, Florence; Maillard, Anne M; Rodriguez-Herreros, Borja; Pain, Aurèlie; Richetin, Sonia; 16p11.2 European Consortium; Simons Searchlight Consortium; Melie-Garcia, Lester; Kushan, Leila; Silva, Ana I; van den Bree, Marianne B M; Linden, David E J; Owen, Michael J; Hall, Jeremy; Lippé, Sarah; Chakravarty, Mallar; Bzdok, Danilo; Bearden, Carrie E; Draganski, Bogdan; Jacquemont, Sébastien	July 20, 2021	Not Determined
34261699	Create Study	Mitochondrial Proteostasis Requires Genes Encoded in a Neurodevelopmental Syndrome Locus.	The Journal of neuroscience : the official journal of the Society for Neuroscience	Gokhale, Avanti; Lee, Chelsea E; Zlatic, Stephanie A; Freeman, Amanda A H; Shearing, Nicole; Hartwig, Cortnie; Ogunbona, Oluwaseun; Bassell, Julia L; Wynne, Meghan E; Werner, Erica; Xu, Chongchong; Wen, Zhexing; Duong, Duc; Seyfried, Nicholas T; Bearden, Carrie E; Oláh, Viktor János; Rowan, Matthew J M; Glausier, Jill R; Lewis, David A; Faundez, Victor	August 4, 2021	Not Determined
34126928	Create Study	Inter-rater reliability of subthreshold psychotic symptoms in individuals with 22q11.2 deletion syndrome.	Journal of neurodevelopmental disorders	Moore, Tyler M; Salzer, Deby; Bearden, Carrie E; Calkins, Monica E; Kates, Wendy R; Kushan, Leila; Gallagher, Robert Sean; Frumer, Dafna Sofrin; Weinberger, Ronnie; McDonald-McGinn, Donna M; Gur, Raquel E; Gothelf, Doron	June 14, 2021	Not Determined
33863277	Create Study	Social cognition in 22q11.2 deletion syndrome and idiopathic developmental neuropsychiatric disorders.	Journal of neurodevelopmental disorders	Jalal, Rhideeta; Nair, Aarti; Lin, Amy; Eckfeld, Ariel; Kushan, Leila; Zinberg, Jamie; Karlsgodt, Katherine H; Cannon, Tyrone D; Bearden, Carrie E	April 17, 2021	Not Determined
33850128	Create Study	Differences in subcortico-cortical interactions identified from connectome and microcircuit models in autism.	Nature communications	Park, Bo-Yong; Hong, Seok-Jun; Valk, Sofie L; Paquola, Casey; Benkarim, Oualid; Bethlehem, Richard A I; Di Martino, Adriana; Milham, Michael P; Gozzi, Alessandro; Yeo, B T Thomas; Smallwood, Jonathan; Bernhardt, Boris C	April 13, 2021	Not Determined
33812299	Create Study	Structural and functional brain alterations revealed by neuroimaging in CNV carriers.	Current opinion in genetics & development	Moreau, Clara A; Ching, Christopher Rk; Kumar, Kuldeep; Jacquemont, Sebastien; Bearden, Carrie E	June 1, 2021	Not Determined
33782512	Create Study	A normative chart for cognitive development in a genetically selected population.	Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology	Fiksinski, Ania M; Bearden, Carrie E; Bassett, Anne S; Kahn, René S; Zinkstok, Janneke R; Hooper, Stephen R; Tempelaar, Wanda; McDonald-McGinn, Donna; Swillen, Ann; Emanuel, Beverly; Morrow, Bernice; Gur, Raquel; Chow, Eva; van den Bree, Marianne; Vermeesch, Joris; Warren, Stephen; Owen, Michael; van Amelsvoort, Therese; Eliez, Stephan; Gothelf, Doron; Arango, Celso; Kates, Wendy; Simon, Tony; Murphy, Kieran; Repetto, Gabriela; Suner, Damian Heine; Vicari, Stefano; Cubells, Joseph; Armando, Marco; Philip, Nicole; Campbell, Linda; Garcia-Minaur, Sixto; Schneider, Maude; Shashi, Vandana; 22q11DS International Consortium on Brain and Behavior; Vorstman, Jacob; Breetvelt, Elemi J	June 1, 2022	Not Determined
33638978	Create Study	Prioritizing Genetic Contributors to Cortical Alterations in 22q11.2 Deletion Syndrome Using Imaging Transcriptomics.	Cerebral cortex (New York, N.Y. : 1991)	Forsyth, Jennifer K; Mennigen, Eva; Lin, Amy; Sun, Daqiang; Vajdi, Ariana; Kushan-Wells, Leila; Ching, Christopher R K; Villalon-Reina, Julio E; Thompson, Paul M; 22q11.2 ENIGMA Consortium; Bearden, Carrie E	June 10, 2021	Not Determined
33615640	Create Study	Effects of copy number variations on brain structure and risk for psychiatric illness: Large-scale studies from the ENIGMA working groups on CNVs.	Human brain mapping	Sønderby, Ida E; Ching, Christopher R K; Thomopoulos, Sophia I; van der Meer, Dennis; Sun, Daqiang; Villalon-Reina, Julio E; Agartz, Ingrid; Amunts, Katrin; Arango, Celso; Armstrong, Nicola J; Ayesa-Arriola, Rosa; Bakker, Geor; Bassett, Anne S; Boomsma, Dorret I; Bülow, Robin; Butcher, Nancy J; Calhoun, Vince D; Caspers, Svenja; Chow, Eva W C; Cichon, Sven; Ciufolini, Simone; Craig, Michael C; Crespo-Facorro, Benedicto; Cunningham, Adam C; Dale, Anders M; Dazzan, Paola; de Zubicaray, Greig I; Djurovic, Srdjan; Doherty, Joanne L; Donohoe, Gary; Draganski, Bogdan; Durdle, Courtney A; Ehrlich, Stefan; Emanuel, Beverly S; Espeseth, Thomas; Fisher, Simon E; Ge, Tian; Glahn, David C; Grabe, Hans J; Gur, Raquel E; Gutman, Boris A; Haavik, Jan; Håberg, Asta K; Hansen, Laura A; Hashimoto, Ryota; Hibar, Derrek P; Holmes, Avram J; Hottenga, Jouke-Jan; Hulshoff Pol, Hilleke E; Jalbrzikowski, Maria; Knowles, Emma E M; Kushan, Leila; Linden, David E J; Liu, Jingyu; Lundervold, Astri J; Martin-Brevet, Sandra; Martínez, Kenia; Mather, Karen A; Mathias, Samuel R; McDonald-McGinn, Donna M; McRae, Allan F; Medland, Sarah E; Moberget, Torgeir; Modenato, Claudia; Monereo Sánchez, Jennifer; Moreau, Clara A; Mühleisen, Thomas W; Paus, Tomas; Pausova, Zdenka; Prieto, Carlos; Ragothaman, Anjanibhargavi; Reinbold, Céline S; Reis Marques, Tiago; Repetto, Gabriela M; Reymond, Alexandre; Roalf, David R; Rodriguez-Herreros, Borja; Rucker, James J; Sachdev, Perminder S; Schmitt, James E; Schofield, Peter R; Silva, Ana I; Stefansson, Hreinn; Stein, Dan J; Tamnes, Christian K; Tordesillas-Gutiérrez, Diana; Ulfarsson, Magnus O; Vajdi, Ariana; van 't Ent, Dennis; van den Bree, Marianne B M; Vassos, Evangelos; Vázquez-Bourgon, Javier; Vila-Rodriguez, Fidel; Walters, G Bragi; Wen, Wei; Westlye, Lars T; Wittfeld, Katharina; Zackai, Elaine H; Stefánsson, Kári; Jacquemont, Sebastien; Thompson, Paul M; Bearden, Carrie E; Andreassen, Ole A; ENIGMA-CNV Working Group; ENIGMA 22q11.2 Deletion Syndrome Working Group	January 1, 2022	Not Determined
33558037	Create Study	Risk and Resilience in Extraordinary Times.	Biological psychiatry. Cognitive neuroscience and neuroimaging	Bearden, Carrie E; Karlsgodt, Katherine H	February 1, 2021	Not Determined
33384013	Create Study	A Genetics-First Approach to Dissecting the Heterogeneity of Autism: Phenotypic Comparison of Autism Risk Copy Number Variants.	The American journal of psychiatry	Chawner, Samuel J R A; Doherty, Joanne L; Anney, Richard J L; Antshel, Kevin M; Bearden, Carrie E; Bernier, Raphael; Chung, Wendy K; Clements, Caitlin C; Curran, Sarah R; Cuturilo, Goran; Fiksinski, Ania M; Gallagher, Louise; Goin-Kochel, Robin P; Gur, Raquel E; Hanson, Ellen; Jacquemont, Sebastien; Kates, Wendy R; Kushan, Leila; Maillard, Anne M; McDonald-McGinn, Donna M; Mihaljevic, Marina; Miller, Judith S; Moss, Hayley; Pejovic-Milovancevic, Milica; Schultz, Robert T; Green-Snyder, LeeAnne; Vorstman, Jacob A; Wenger, Tara L; IMAGINE-ID Consortium; Hall, Jeremy; Owen, Michael J; van den Bree, Marianne B M	January 1, 2021	Not Determined
33355124	Create Study	Network structure of the mouse brain connectome with voxel resolution.	Science advances	Coletta, Ludovico; Pagani, Marco; Whitesell, Jennifer D; Harris, Julie A; Bernhardt, Boris; Gozzi, Alessandro	December 1, 2020	Not Determined
33290731	Create Study	Regional, Layer, and Cell-Type-Specific Connectivity of the Mouse Default Mode Network.	Neuron	Whitesell, Jennifer D; Liska, Adam; Coletta, Ludovico; Hirokawa, Karla E; Bohn, Phillip; Williford, Ali; Groblewski, Peter A; Graddis, Nile; Kuan, Leonard; Knox, Joseph E; Ho, Anh; Wakeman, Wayne; Nicovich, Philip R; Nguyen, Thuc Nghi; van Velthoven, Cindy T J; Garren, Emma; Fong, Olivia; Naeemi, Maitham; Henry, Alex M; Dee, Nick; Smith, Kimberly A; Levi, Boaz; Feng, David; Ng, Lydia; Tasic, Bosiljka; Zeng, Hongkui; Mihalas, Stefan; Gozzi, Alessandro; Harris, Julie A	February 3, 2021	Not Determined
33169016	Create Study	Using common genetic variation to examine phenotypic expression and risk prediction in 22q11.2 deletion syndrome.	Nature medicine	Davies, Robert W; Fiksinski, Ania M; Breetvelt, Elemi J; Williams, Nigel M; Hooper, Stephen R; Monfeuga, Thomas; Bassett, Anne S; Owen, Michael J; Gur, Raquel E; Morrow, Bernice E; McDonald-McGinn, Donna M; Swillen, Ann; Chow, Eva W C; van den Bree, Marianne; Emanuel, Beverly S; Vermeesch, Joris R; van Amelsvoort, Therese; Arango, Celso; Armando, Marco; Campbell, Linda E; Cubells, Joseph F; Eliez, Stephan; Garcia-Minaur, Sixto; Gothelf, Doron; Kates, Wendy R; Murphy, Kieran C; Murphy, Clodagh M; Murphy, Declan G; Philip, Nicole; Repetto, Gabriela M; Shashi, Vandana; Simon, Tony J; Suñer, Damiàn Heine; Vicari, Stefano; Scherer, Stephen W; International 22q11.2 Brain and Behavior Consortium; Bearden, Carrie E; Vorstman, Jacob A S	December 1, 2020	Not Determined
33139857	Create Study	Brain morphometry in 22q11.2 deletion syndrome: an exploration of differences in cortical thickness, surface area, and their contribution to cortical volume.	Scientific reports	Gudbrandsen, M; Daly, E; Murphy, C M; Blackmore, C E; Rogdaki, M; Mann, C; Bletsch, A; Kushan, L; Bearden, C E; Murphy, D G M; Craig, M C; Ecker, Christine	November 2, 2020	Not Determined
33077750	Create Study	Mutations associated with neuropsychiatric conditions delineate functional brain connectivity dimensions contributing to autism and schizophrenia.	Nature communications	Moreau, Clara A; Urchs, Sebastian G W; Kuldeep, Kumar; Orban, Pierre; Schramm, Catherine; Dumas, Guillaume; Labbe, Aurélie; Huguet, Guillaume; Douard, Elise; Quirion, Pierre-Olivier; Lin, Amy; Kushan, Leila; Grot, Stephanie; Luck, David; Mendrek, Adrianna; Potvin, Stephane; Stip, Emmanuel; Bourgeron, Thomas; Evans, Alan C; Bearden, Carrie E; Bellec, Pierre; Jacquemont, Sebastien	October 19, 2020	Not Determined
32989314	Create Study	Neuronal defects in a human cellular model of 22q11.2 deletion syndrome.	Nature medicine	Khan, Themasap A; Revah, Omer; Gordon, Aaron; Yoon, Se-Jin; Krawisz, Anna K; Goold, Carleton; Sun, Yishan; Kim, Chul Hoon; Tian, Yuan; Li, Min-Yin; Schaepe, Julia M; Ikeda, Kazuya; Amin, Neal D; Sakai, Noriaki; Yazawa, Masayuki; Kushan, Leila; Nishino, Seiji; Porteus, Matthew H; Rapoport, Judith L; Bernstein, Jonathan A; O'Hara, Ruth; Bearden, Carrie E; Hallmayer, Joachim F; Huguenard, John R; Geschwind, Daniel H; Dolmetsch, Ricardo E; Paşca, Sergiu P	December 1, 2020	Not Determined
32513259	Create Study	Neuroanatomical underpinnings of autism symptomatology in carriers and non-carriers of the 22q11.2 microdeletion.	Molecular autism	Gudbrandsen, Maria; Bletsch, Anke; Mann, Caroline; Daly, Eileen; Murphy, Clodagh M; Stoencheva, Vladimira; Blackmore, Charlotte E; Rogdaki, Maria; Kushan, Leila; Bearden, Carrie E; Murphy, Declan G M; Craig, Michael C; Ecker, Christine	June 2020	Not Determined
32420595	Create Study	Patterns of Cortical Folding Associated with Autistic Symptoms in Carriers and Noncarriers of the 22q11.2 Microdeletion.	Cerebral cortex (New York, N.Y. : 1991)	Gudbrandsen, Maria; Mann, Caroline; Bletsch, Anke; Daly, Eileen; Murphy, Clodagh M; Stoencheva, Vladimira; Blackmore, Charlotte E; Rogdaki, Maria; Kushan, Leila; Bearden, Carrie E; Murphy, Declan G M; Craig, Michael C; Ecker, Christine	September 3, 2020	Not Determined
32301246	Create Study	ENIGMA-DTI: Translating reproducible white matter deficits into personalized vulnerability metrics in cross-diagnostic psychiatric research.	Human brain mapping	Kochunov, Peter; Hong, L Elliot; Dennis, Emily L; Morey, Rajendra A; Tate, David F; Wilde, Elisabeth A; Logue, Mark; Kelly, Sinead; Donohoe, Gary; Favre, Pauline; Houenou, Josselin; Ching, Christopher R K; Holleran, Laurena; Andreassen, Ole A; van Velzen, Laura S; Schmaal, Lianne; Villalón-Reina, Julio E; Bearden, Carrie E; Piras, Fabrizio; Spalletta, Gianfranco; van den Heuvel, Odile A; Veltman, Dick J; Stein, Dan J; Ryan, Meghann C; Tan, Yunlong; van Erp, Theo G M; Turner, Jessica A; Haddad, Liz; Nir, Talia M; Glahn, David C; Thompson, Paul M; Jahanshad, Neda	January 2022	Not Determined
32198361	Create Study	ENIGMA and global neuroscience: A decade of large-scale studies of the brain in health and disease across more than 40 countries.	Translational psychiatry	Thompson, Paul M; Jahanshad, Neda; Ching, Christopher R K; Salminen, Lauren E; Thomopoulos, Sophia I; Bright, Joanna; Baune, Bernhard T; Bertolín, Sara; Bralten, Janita; Bruin, Willem B; Bülow, Robin; Chen, Jian; Chye, Yann; Dannlowski, Udo; de Kovel, Carolien G F; Donohoe, Gary; Eyler, Lisa T; Faraone, Stephen V; Favre, Pauline; Filippi, Courtney A; Frodl, Thomas; Garijo, Daniel; Gil, Yolanda; Grabe, Hans J; Grasby, Katrina L; Hajek, Tomas; Han, Laura K M; Hatton, Sean N; Hilbert, Kevin; Ho, Tiffany C; Holleran, Laurena; Homuth, Georg; Hosten, Norbert; Houenou, Josselin; Ivanov, Iliyan; Jia, Tianye; Kelly, Sinead; Klein, Marieke; Kwon, Jun Soo; Laansma, Max A; Leerssen, Jeanne; Lueken, Ulrike; Nunes, Abraham; Neill, Joseph O'; Opel, Nils; Piras, Fabrizio; Piras, Federica; Postema, Merel C; Pozzi, Elena; Shatokhina, Natalia; Soriano-Mas, Carles; Spalletta, Gianfranco; Sun, Daqiang; Teumer, Alexander; Tilot, Amanda K; Tozzi, Leonardo; van der Merwe, Celia; Van Someren, Eus J W; van Wingen, Guido A; Völzke, Henry; Walton, Esther; Wang, Lei; Winkler, Anderson M; Wittfeld, Katharina; Wright, Margaret J; Yun, Je-Yeon; Zhang, Guohao; Zhang-James, Yanli; Adhikari, Bhim M; Agartz, Ingrid; Aghajani, Moji; Aleman, André; Althoff, Robert R; Altmann, Andre; Andreassen, Ole A; Baron, David A; Bartnik-Olson, Brenda L; Marie Bas-Hoogendam, Janna; Baskin-Sommers, Arielle R; Bearden, Carrie E; Berner, Laura A; Boedhoe, Premika S W; Brouwer, Rachel M; Buitelaar, Jan K; Caeyenberghs, Karen; Cecil, Charlotte A M; Cohen, Ronald A; Cole, James H; Conrod, Patricia J; De Brito, Stephane A; de Zwarte, Sonja M C; Dennis, Emily L; Desrivieres, Sylvane; Dima, Danai; Ehrlich, Stefan; Esopenko, Carrie; Fairchild, Graeme; Fisher, Simon E; Fouche, Jean-Paul; Francks, Clyde; Frangou, Sophia; Franke, Barbara; Garavan, Hugh P; Glahn, David C; Groenewold, Nynke A; Gurholt, Tiril P; Gutman, Boris A; Hahn, Tim; Harding, Ian H; Hernaus, Dennis; Hibar, Derrek P; Hillary, Frank G; Hoogman, Martine; Hulshoff Pol, Hilleke E; Jalbrzikowski, Maria; Karkashadze, George A; Klapwijk, Eduard T; Knickmeyer, Rebecca C; Kochunov, Peter; Koerte, Inga K; Kong, Xiang-Zhen; Liew, Sook-Lei; Lin, Alexander P; Logue, Mark W; Luders, Eileen; Macciardi, Fabio; Mackey, Scott; Mayer, Andrew R; McDonald, Carrie R; McMahon, Agnes B; Medland, Sarah E; Modinos, Gemma; Morey, Rajendra A; Mueller, Sven C; Mukherjee, Pratik; Namazova-Baranova, Leyla; Nir, Talia M; Olsen, Alexander; Paschou, Peristera; Pine, Daniel S; Pizzagalli, Fabrizio; Rentería, Miguel E; Rohrer, Jonathan D; Sämann, Philipp G; Schmaal, Lianne; Schumann, Gunter; Shiroishi, Mark S; Sisodiya, Sanjay M; Smit, Dirk J A; Sønderby, Ida E; Stein, Dan J; Stein, Jason L; Tahmasian, Masoud; Tate, David F; Turner, Jessica A; van den Heuvel, Odile A; van der Wee, Nic J A; van der Werf, Ysbrand D; van Erp, Theo G M; van Haren, Neeltje E M; van Rooij, Daan; van Velzen, Laura S; Veer, Ilya M; Veltman, Dick J; Villalon-Reina, Julio E; Walter, Henrik; Whelan, Christopher D; Wilde, Elisabeth A; Zarei, Mojtaba; Zelman, Vladimir; ENIGMA Consortium	March 2020	Not Determined
32143830	Create Study	Reciprocal Copy Number Variations at 22q11.2 Produce Distinct and Convergent Neurobehavioral Impairments Relevant for Schizophrenia and Autism Spectrum Disorder.	Biological psychiatry	Lin, Amy; Vajdi, Ariana; Kushan-Wells, Leila; Helleman, Gerhard; Hansen, Laura Pacheco; Jonas, Rachel K; Jalbrzikowski, Maria; Kingsbury, Lyle; Raznahan, Armin; Bearden, Carrie E	August 2020	Not Determined
32046535	Create Study	Mapping Subcortical Brain Alterations in 22q11.2 Deletion Syndrome: Effects of Deletion Size and Convergence With Idiopathic Neuropsychiatric Illness.	The American journal of psychiatry	Ching, Christopher R K; Gutman, Boris A; Sun, Daqiang; Villalon Reina, Julio; Ragothaman, Anjanibhargavi; Isaev, Dmitry; Zavaliangos-Petropulu, Artemis; Lin, Amy; Jonas, Rachel K; Kushan, Leila; Pacheco-Hansen, Laura; Vajdi, Ariana; Forsyth, Jennifer K; Jalbrzikowski, Maria; Bakker, Geor; van Amelsvoort, Therese; Antshel, Kevin M; Fremont, Wanda; Kates, Wendy R; Campbell, Linda E; McCabe, Kathryn L; Craig, Michael C; Daly, Eileen; Gudbrandsen, Maria; Murphy, Clodagh M; Murphy, Declan G; Murphy, Kieran C; Fiksinski, Ania; Koops, Sanne; Vorstman, Jacob; Crowley, T Blaine; Emanuel, Beverly S; Gur, Raquel E; McDonald-McGinn, Donna M; Roalf, David R; Ruparel, Kosha; Schmitt, J Eric; Zackai, Elaine H; Durdle, Courtney A; Goodrich-Hunsaker, Naomi J; Simon, Tony J; Bassett, Anne S; Butcher, Nancy J; Chow, Eva W C; Vila-Rodriguez, Fidel; Cunningham, Adam; Doherty, Joanne; Linden, David E; Moss, Hayley; Owen, Michael J; van den Bree, Marianne; Crossley, Nicolas A; Repetto, Gabriela M; Thompson, Paul M; Bearden, Carrie E	July 2020	Not Determined
32015465	Create Study	Genetic contributors to risk of schizophrenia in the presence of a 22q11.2 deletion.	Molecular psychiatry	Cleynen, Isabelle; Engchuan, Worrawat; Hestand, Matthew S; Heung, Tracy; Holleman, Aaron M; Johnston, H Richard; Monfeuga, Thomas; McDonald-McGinn, Donna M; Gur, Raquel E; Morrow, Bernice E; Swillen, Ann; Vorstman, Jacob A S; Bearden, Carrie E; Chow, Eva W C; van den Bree, Marianne; Emanuel, Beverly S; Vermeesch, Joris R; Warren, Stephen T; Owen, Michael J; Chopra, Pankaj; Cutler, David J; Duncan, Richard; Kotlar, Alex V; Mulle, Jennifer G; Voss, Anna J; Zwick, Michael E; Diacou, Alexander; Golden, Aaron; Guo, Tingwei; Lin, Jhih-Rong; Wang, Tao; Zhang, Zhengdong; Zhao, Yingjie; Marshall, Christian; Merico, Daniele; Jin, Andrea; Lilley, Brenna; Salmons, Harold I; Tran, Oanh; Holmans, Peter; Pardinas, Antonio; Walters, James T R; Demaerel, Wolfram; Boot, Erik; Butcher, Nancy J; Costain, Gregory A; Lowther, Chelsea; Evers, Rens; van Amelsvoort, Therese A M J; van Duin, Esther; Vingerhoets, Claudia; Breckpot, Jeroen; Devriendt, Koen; Vergaelen, Elfi; Vogels, Annick; Crowley, T Blaine; McGinn, Daniel E; Moss, Edward M; Sharkus, Robert J; Unolt, Marta; Zackai, Elaine H; Calkins, Monica E; Gallagher, Robert S; Gur, Ruben C; Tang, Sunny X; Fritsch, Rosemarie; Ornstein, Claudia; Repetto, Gabriela M; Breetvelt, Elemi; Duijff, Sasja N; Fiksinski, Ania; Moss, Hayley; Niarchou, Maria; Murphy, Kieran C; Prasad, Sarah E; Daly, Eileen M; Gudbrandsen, Maria; Murphy, Clodagh M; Murphy, Declan G; Buzzanca, Antonio; Fabio, Fabio Di; Digilio, Maria C; Pontillo, Maria; Marino, Bruno; Vicari, Stefano; Coleman, Karlene; Cubells, Joseph F; Ousley, Opal Y; Carmel, Miri; Gothelf, Doron; Mekori-Domachevsky, Ehud; Michaelovsky, Elena; Weinberger, Ronnie; Weizman, Abraham; Kushan, Leila; Jalbrzikowski, Maria; Armando, Marco; Eliez, Stéphan; Sandini, Corrado; Schneider, Maude; Béna, Frédérique Sloan; Antshel, Kevin M; Fremont, Wanda; Kates, Wendy R; Belzeaux, Raoul; Busa, Tiffany; Philip, Nicole; Campbell, Linda E; McCabe, Kathryn L; Hooper, Stephen R; Schoch, Kelly; Shashi, Vandana; Simon, Tony J; Tassone, Flora; Arango, Celso; Fraguas, David; García-Miñaúr, Sixto; Morey-Canyelles, Jaume; Rosell, Jordi; Suñer, Damià H; Raventos-Simic, Jasna; International 22q11.2DS Brain and Behavior Consortium; Epstein, Michael P; Williams, Nigel M; Bassett, Anne S	August 2021	Not Determined
31917352	Create Study	Acute and Repeated Intranasal Oxytocin Differentially Modulate Brain-wide Functional Connectivity.	Neuroscience	Pagani, Marco; De Felice, Alessia; Montani, Caterina; Galbusera, Alberto; Papaleo, Francesco; Gozzi, Alessandro	October 1, 2020	Not Determined
31870554	Create Study	Complete Sequence of the 22q11.2 Allele in 1,053 Subjects with 22q11.2 Deletion Syndrome Reveals Modifiers of Conotruncal Heart Defects.	American journal of human genetics	Zhao, Yingjie; Diacou, Alexander; Johnston, H Richard; Musfee, Fadi I; McDonald-McGinn, Donna M; McGinn, Daniel; Crowley, T Blaine; Repetto, Gabriela M; Swillen, Ann; Breckpot, Jeroen; Vermeesch, Joris R; Kates, Wendy R; Digilio, M Cristina; Unolt, Marta; Marino, Bruno; Pontillo, Maria; Armando, Marco; Di Fabio, Fabio; Vicari, Stefano; van den Bree, Marianne; Moss, Hayley; Owen, Michael J; Murphy, Kieran C; Murphy, Clodagh M; Murphy, Declan; Schoch, Kelly; Shashi, Vandana; Tassone, Flora; Simon, Tony J; Shprintzen, Robert J; Campbell, Linda; Philip, Nicole; Heine-Suñer, Damian; García-Miñaúr, Sixto; Fernández, Luis; International 22q11.2 Brain and Behavior Consortium; Bearden, Carrie E; Vingerhoets, Claudia; van Amelsvoort, Therese; Eliez, Stephan; Schneider, Maude; Vorstman, Jacob A S; Gothelf, Doron; Zackai, Elaine; Agopian, A J; Gur, Raquel E; Bassett, Anne S; Emanuel, Beverly S; Goldmuntz, Elizabeth; Mitchell, Laura E; Wang, Tao; Morrow, Bernice E	January 2020	Not Determined
31856383	Create Study	Fast and accurate initialization of the free-water imaging model parameters from multi-shell diffusion MRI.	NMR in biomedicine	Bergmann, Ørjan; Henriques, Rafael; Westin, Carl-Fredrik; Pasternak, Ofer	March 2020	Not Determined
31548702	Create Study	A framework for the investigation of rare genetic disorders in neuropsychiatry.	Nature medicine	Sanders, Stephan J; Sahin, Mustafa; Hostyk, Joseph; Thurm, Audrey; Jacquemont, Sebastien; Avillach, Paul; Douard, Elise; Martin, Christa L; Modi, Meera E; Moreno-De-Luca, Andres; Raznahan, Armin; Anticevic, Alan; Dolmetsch, Ricardo; Feng, Guoping; Geschwind, Daniel H; Glahn, David C; Goldstein, David B; Ledbetter, David H; Mulle, Jennifer G; Pasca, Sergiu P; Samaco, Rodney; Sebat, Jonathan; Pariser, Anne; Lehner, Thomas; Gur, Raquel E; Bearden, Carrie E	October 2019	Not Determined
31500805	Create Study	Synaptic and Gene Regulatory Mechanisms in Schizophrenia, Autism, and 22q11.2 Copy Number Variant-Mediated Risk for Neuropsychiatric Disorders.	Biological psychiatry	Forsyth, Jennifer K; Nachun, Daniel; Gandal, Michael J; Geschwind, Daniel H; Anderson, Ariana E; Coppola, Giovanni; Bearden, Carrie E	January 2020	Not Determined
31358905	Create Study	Altered white matter microstructure in 22q11.2 deletion syndrome: a multisite diffusion tensor imaging study.	Molecular psychiatry	Villalón-Reina, Julio E; Martínez, Kenia; Qu, Xiaoping; Ching, Christopher R K; Nir, Talia M; Kothapalli, Deydeep; Corbin, Conor; Sun, Daqiang; Lin, Amy; Forsyth, Jennifer K; Kushan, Leila; Vajdi, Ariana; Jalbrzikowski, Maria; Hansen, Laura; Jonas, Rachel K; van Amelsvoort, Therese; Bakker, Geor; Kates, Wendy R; Antshel, Kevin M; Fremont, Wanda; Campbell, Linda E; McCabe, Kathryn L; Daly, Eileen; Gudbrandsen, Maria; Murphy, Clodagh M; Murphy, Declan; Craig, Michael; Emanuel, Beverly; McDonald-McGinn, Donna M; Vorstman, Jacob A S; Fiksinski, Ania M; Koops, Sanne; Ruparel, Kosha; Roalf, David; Gur, Raquel E; Eric Schmitt, J; Simon, Tony J; Goodrich-Hunsaker, Naomi J; Durdle, Courtney A; Doherty, Joanne L; Cunningham, Adam C; van den Bree, Marianne; Linden, David E J; Owen, Michael; Moss, Hayley; Kelly, Sinead; Donohoe, Gary; Murphy, Kieran C; Arango, Celso; Jahanshad, Neda; Thompson, Paul M; Bearden, Carrie E	November 2020	Not Determined
31303490	Create Study	Infraslow State Fluctuations Govern Spontaneous fMRI Network Dynamics.	Current biology : CB	Gutierrez-Barragan, Daniel; Basson, M Albert; Panzeri, Stefano; Gozzi, Alessandro	July 22, 2019	Not Determined
30978492	Create Study	MK-curve - Characterizing the relation between mean kurtosis and alterations in the diffusion MRI signal.	NeuroImage	Zhang, Fan; Ning, Lipeng; O'Donnell, Lauren J; Pasternak, Ofer	August 2019	Not Determined
30833507	Create Study	Systems Analysis of the 22q11.2 Microdeletion Syndrome Converges on a Mitochondrial Interactome Necessary for Synapse Function and Behavior.	The Journal of neuroscience : the official journal of the Society for Neuroscience	Gokhale, Avanti; Hartwig, Cortnie; Freeman, Amanda A H; Bassell, Julia L; Zlatic, Stephanie A; Sapp Savas, Christie; Vadlamudi, Trishna; Abudulai, Farida; Pham, Tyler T; Crocker, Amanda; Werner, Erica; Wen, Zhexing; Repetto, Gabriela M; Gogos, Joseph A; Claypool, Steven M; Forsyth, Jennifer K; Bearden, Carrie E; Glausier, Jill; Lewis, David A; Seyfried, Nicholas T; Kwong, Jennifer Q; Faundez, Victor	May 2019	Not Determined
30631427	Create Study	The many roads to psychosis: recent advances in understanding risk and mechanisms.	F1000Research	Bearden, Carrie E; Forsyth, Jennifer K	January 2018	Not Determined
30593497	Create Study	Aberrant Somatosensory Processing and Connectivity in Mice Lacking Engrailed-2.	The Journal of neuroscience : the official journal of the Society for Neuroscience	Chelini, Gabriele; Zerbi, Valerio; Cimino, Luca; Grigoli, Andrea; Markicevic, Marija; Libera, Francesco; Robbiati, Sergio; Gadler, Mattia; Bronzoni, Silvia; Miorelli, Silvia; Galbusera, Alberto; Gozzi, Alessandro; Casarosa, Simona; Provenzano, Giovanni; Bozzi, Yuri	February 20, 2019	Not Determined
30522971	Create Study	Abnormalities in gray matter microstructure in young adults with 22q11.2 deletion syndrome.	NeuroImage. Clinical	Kikinis, Zora; Makris, Nikos; Sydnor, Valerie J; Bouix, Sylvain; Pasternak, Ofer; Coman, Ioana L; Antshel, Kevin M; Fremont, Wanda; Kubicki, Marek R; Shenton, Martha E; Kates, Wendy R; Rathi, Yogesh	January 2019	Not Determined
30478034	Create Study	Dissociable Disruptions in Thalamic and Hippocampal Resting-State Functional Connectivity in Youth with 22q11.2 Deletions.	The Journal of neuroscience : the official journal of the Society for Neuroscience	Schleifer, Charles; Lin, Amy; Kushan, Leila; Ji, Jie Lisa; Yang, Genevieve; Bearden, Carrie E; Anticevic, Alan	February 2019	Not Determined
30289625	Create Study	Variance of IQ is partially dependent on deletion type among 1,427 22q11.2 deletion syndrome subjects.	American journal of medical genetics. Part A	Zhao, Yingjie; Guo, Tingwei; Fiksinski, Ania; Breetvelt, Elemi; McDonald-McGinn, Donna M; Crowley, Terrence B; Diacou, Alexander; Schneider, Maude; Eliez, Stephan; Swillen, Ann; Breckpot, Jeroen; Vermeesch, Joris; Chow, Eva W C; Gothelf, Doron; Duijff, Sasja; Evers, Rens; van Amelsvoort, Thérèse A; van den Bree, Marianne; Owen, Michael; Niarchou, Maria; Bearden, Carrie E; Ornstein, Claudia; Pontillo, Maria; Buzzanca, Antonino; Vicari, Stefano; Armando, Marco; Murphy, Kieran C; Murphy, Clodagh; Garcia-Minaur, Sixto; Philip, Nicole; Campbell, Linda; Morey-Cañellas, Jaume; Raventos, Jasna; Rosell, Jordi; Heine-Suner, Damian; Shprintzen, Robert J; Gur, Raquel E; Zackai, Elaine; Emanuel, Beverly S; Wang, Tao; Kates, Wendy R; Bassett, Anne S; Vorstman, Jacob A S; Morrow, Bernice E; International 22q11.2 Brain and Behavior Consortium	October 1, 2018	Relevant
30272146	Create Study	The Neuroanatomy of Autism Spectrum Disorder Symptomatology in 22q11.2 Deletion Syndrome.	Cerebral cortex (New York, N.Y. : 1991)	Gudbrandsen, M; Daly, E; Murphy, C M; Wichers, R H; Stoencheva, V; Perry, E; Andrews, D; Blackmore, C E; Rogdaki, M; Kushan, L; Bearden, C E; Murphy, D G M; Craig, M C; Ecker, C	July 2019	Not Determined
30093352	Create Study	Attention deficit hyperactivity disorder symptoms as antecedents of later psychotic outcomes in 22q11.2 deletion syndrome.	Schizophrenia research	Niarchou, Maria; Chawner, Samuel J R A; Fiksinski, Ania; Vorstman, Jacob A S; Maeder, Johanna; Schneider, Maude; Eliez, Stephan; Armando, Marco; Pontillo, Maria; Vicari, Stefano; McDonald-McGinn, Donna M; Emanuel, Beverly S; Zackai, Elaine H; Bearden, Carrie E; Shashi, Vandana; Hooper, Stephen R; Owen, Michael J; Gur, Raquel E; Wray, Naomi R; van den Bree, Marianne B M; Thapar, Anita; International 22q11.2 Deletion Syndrome Brain and Behavior Consortium	February 1, 2019	Not Determined
29956456	Create Study	The relation of atypical antipsychotic use and stress with weight in individuals at clinical high risk for psychosis.	Stress and health : journal of the International Society for the Investigation of Stress	Hampton, Joya N; Trotman, Hanan D; Addington, Jean; Bearden, Carrie E; Cadenhead, Kristin S; Cannon, Tyrone D; Cornblatt, Barbara A; Mathalon, Daniel H; McGlashan, Thomas H; Tsuang, Ming T; Perkins, Diana O; Seidman, Larry J; Woods, Scott W; Walker, Elaine F	December 2018	Not Relevant
29895892	Create Study	Large-scale mapping of cortical alterations in 22q11.2 deletion syndrome: Convergence with idiopathic psychosis and effects of deletion size.	Molecular psychiatry	Sun, Daqiang; Ching, Christopher R K; Lin, Amy; Forsyth, Jennifer K; Kushan, Leila; Vajdi, Ariana; Jalbrzikowski, Maria; Hansen, Laura; Villalon-Reina, Julio E; Qu, Xiaoping; Jonas, Rachel K; van Amelsvoort, Therese; Bakker, Geor; Kates, Wendy R; Antshel, Kevin M; Fremont, Wanda; Campbell, Linda E; McCabe, Kathryn L; Daly, Eileen; Gudbrandsen, Maria; Murphy, Clodagh M; Murphy, Declan; Craig, Michael; Vorstman, Jacob; Fiksinski, Ania; Koops, Sanne; Ruparel, Kosha; Roalf, David R; Gur, Raquel E; Schmitt, J Eric; Simon, Tony J; Goodrich-Hunsaker, Naomi J; Durdle, Courtney A; Bassett, Anne S; Chow, Eva W C; Butcher, Nancy J; Vila-Rodriguez, Fidel; Doherty, Joanne; Cunningham, Adam; van den Bree, Marianne B M; Linden, David E J; Moss, Hayley; Owen, Michael J; Murphy, Kieran C; McDonald-McGinn, Donna M; Emanuel, Beverly; van Erp, Theo G M; Turner, Jessica A; Thompson, Paul M; Bearden, Carrie E	August 2020	Relevant
29729390	Create Study	Advances in microstructural diffusion neuroimaging for psychiatric disorders.	NeuroImage	Pasternak O, Kelly S, Sydnor VJ, Shenton ME	November 2018	Not Determined
29653094	Create Study	Biotypes: The Tip of the Research Domain Criteria Iceberg.	Biological psychiatry. Cognitive neuroscience and neuroimaging	Jalbrzikowski, Maria; Bearden, Carrie E	November 1, 2016	Not Determined
29376674	Create Study	Cognitive genomics: Searching for the genetic roots of neuropsychological functioning.	Neuropsychology	Bearden, Carrie E; Glahn, David C	November 2017	Relevant
29361080	Create Study	Deletion size analysis of 1680 22q11.2DS subjects identifies a new recombination hotspot on chromosome 22q11.2.	Human molecular genetics	Guo, Tingwei; Diacou, Alexander; Nomaru, Hiroko; McDonald-McGinn, Donna M; Hestand, Matthew; Demaerel, Wolfram; Zhang, Liangtian; Zhao, Yingjie; Ujueta, Francisco; Shan, Jidong; Montagna, Cristina; Zheng, Deyou; Crowley, Terrence B; Kushan-Wells, Leila; Bearden, Carrie E; Kates, Wendy R; Gothelf, Doron; Schneider, Maude; Eliez, Stephan; Breckpot, Jeroen; Swillen, Ann; Vorstman, Jacob; Zackai, Elaine; Benavides Gonzalez, Felipe; Repetto, Gabriela M; Emanuel, Beverly S; Bassett, Anne S; Vermeesch, Joris R; Marshall, Christian R; Morrow, Bernice E; International Chromosome 22q11.2, International 22q11.2 Brain and Behavior Consortia	April 2018	Relevant
29025761	Create Study	Genome-Wide Association Study to Find Modifiers for Tetralogy of Fallot in the 22q11.2 Deletion Syndrome Identifies Variants in the GPR98 Locus on 5q14.3.	Circulation. Cardiovascular genetics	Guo, Tingwei; Repetto, Gabriela M; McDonald McGinn, Donna M; Chung, Jonathan H; Nomaru, Hiroko; Campbell, Christopher L; Blonska, Anna; Bassett, Anne S; Chow, Eva W C; Mlynarski, Elisabeth E; Swillen, Ann; Vermeesch, Joris; Devriendt, Koen; Gothelf, Doron; Carmel, Miri; Michaelovsky, Elena; Schneider, Maude; Eliez, Stephan; Antonarakis, Stylianos E; Coleman, Karlene; Tomita-Mitchell, Aoy; Mitchell, Michael E; Digilio, M Cristina; Dallapiccola, Bruno; Marino, Bruno; Philip, Nicole; Busa, Tiffany; Kushan-Wells, Leila; Bearden, Carrie E; Piotrowicz, Małgorzata; Hawuła, Wanda; Roberts, Amy E; Tassone, Flora; Simon, Tony J; van Duin, Esther D A; van Amelsvoort, Thérèse A; Kates, Wendy R; Zackai, Elaine; Johnston, H Richard; Cutler, David J; Agopian, A J; Goldmuntz, Elizabeth; Mitchell, Laura E; Wang, Tao; Emanuel, Beverly S; Morrow, Bernice E; International 22q11.2 Consortium/Brain and Behavior Consortium*	October 1, 2017	Not Determined
28761081	Create Study	A neurogenetic model for the study of schizophrenia spectrum disorders: the International 22q11.2 Deletion Syndrome Brain Behavior Consortium.	Molecular psychiatry	Gur, R E; Bassett, A S; McDonald-McGinn, D M; Bearden, C E; Chow, E; Emanuel, B S; Owen, M; Swillen, A; Van den Bree, M; Vermeesch, J; Vorstman, J A S; Warren, S; Lehner, T; Morrow, B	December 2017	Relevant
28750581	Create Study	Rare Genome-Wide Copy Number Variation and Expression of Schizophrenia in 22q11.2 Deletion Syndrome.	The American journal of psychiatry	Bassett, Anne S; Lowther, Chelsea; Merico, Daniele; Costain, Gregory; Chow, Eva W C; van Amelsvoort, Therese; McDonald-McGinn, Donna; Gur, Raquel E; Swillen, Ann; Van den Bree, Marianne; Murphy, Kieran; Gothelf, Doron; Bearden, Carrie E; Eliez, Stephan; Kates, Wendy; Philip, Nicole; Sashi, Vandana; Campbell, Linda; Vorstman, Jacob; Cubells, Joseph; Repetto, Gabriela M; Simon, Tony; Boot, Erik; Heung, Tracy; Evers, Rens; Vingerhoets, Claudia; van Duin, Esther; Zackai, Elaine; Vergaelen, Elfi; Devriendt, Koen; Vermeesch, Joris R; Owen, Michael; Murphy, Clodagh; Michaelovosky, Elena; Kushan, Leila; Schneider, Maude; Fremont, Wanda; Busa, Tiffany; Hooper, Stephen; McCabe, Kathryn; Duijff, Sasja; Isaev, Karin; Pellecchia, Giovanna; Wei, John; Gazzellone, Matthew J; Scherer, Stephen W; Emanuel, Beverly S; Guo, Tingwei; Morrow, Bernice E; Marshall, Christian R; International 22q11.2DS Brain and Behavior Consortium	November 2017	Relevant
28536274	Create Study	Mapping 22q11.2 Gene Dosage Effects on Brain Morphometry.	The Journal of neuroscience : the official journal of the Society for Neuroscience	Lin A, Ching CRK, Vajdi A, Sun D, Jonas RK, Jalbrzikowski M, Kushan-Wells L, Pacheco Hansen L, Krikorian E, Gutman B, Dokoru D, Helleman G, Thompson PM, Bearden CE	June 2017	Relevant
28426957	Create Study	Emerging Global Initiatives in Neurogenetics: The Enhancing Neuroimaging Genetics through Meta-analysis (ENIGMA) Consortium.	Neuron	Bearden, Carrie E; Thompson, Paul M	April 2017	Relevant
28383675	Create Study	Intrinsic Connectivity Network-Based Classification and Detection of Psychotic Symptoms in Youth With 22q11.2 Deletions.	Cerebral cortex (New York, N.Y. : 1991)	Schreiner M, Forsyth JK, Karlsgodt KH, Anderson AE, Hirsh N, Kushan L, Uddin LQ, Mattiacio L, Coman IL, Kates WR, Bearden CE	June 2017	Relevant
28367513	Create Study	Categorical versus dimensional approaches to autism-associated intermediate phenotypes in 22q11.2 microdeletion syndrome.	Biological psychiatry. Cognitive neuroscience and neuroimaging	Jalbrzikowski, Maria; Ahmed, Khwaja Hamzah; Patel, Arati; Jonas, Rachel; Kushan, Leila; Chow, Carolyn; Bearden, Carrie E	January 2017	Relevant
28204757	Create Study	Subthreshold Psychosis in 22q11.2 Deletion Syndrome: Multisite Naturalistic Study.	Schizophrenia bulletin	Weisman, Omri; Guri, Yael; Gur, Raquel E; McDonald-McGinn, Donna M; Calkins, Monica E; Tang, Sunny X; Emanuel, Beverly; Zackai, Elaine H; Eliez, Stephan; Schneider, Maude; Schaer, Marie; Kates, Wendy R; Antshel, Kevin M; Fremont, Wanda; Shashi, Vandana; Hooper, Stephen R; Armando, Marco; Vicari, Stefano; Pontillo, Maria; Kushan, Leila; Jalbrzikowski, Maria; Bearden, Carrie E; Cubells, Joseph F; Ousley, Opal Y; Walker, Elaine F; Simon, Tony J; Stoddard, Joel; Niendam, Tara A; van den Bree, Marianne B M; Gothelf, Doron; International Consortium on Brain and Behavior in 22q11.2 Deletion Syndrome	September 2017	Relevant
28190639	Create Study	Characterizing white matter changes in chronic schizophrenia: A free-water imaging multi-site study.	Schizophrenia research	Oestreich, Lena K L; Lyall, Amanda E; Pasternak, Ofer; Kikinis, Zora; Newell, Dominick T; Savadjiev, Peter; Bouix, Sylvain; Shenton, Martha E; Kubicki, Marek; Australian Schizophrenia Research Bank; Whitford, Thomas J; McCarthy-Jones, Simon	November 2017	Not Relevant
26509118	Create Study	Neural mechanisms of response inhibition and impulsivity in 22q11.2 deletion carriers and idiopathic attention deficit hyperactivity disorder.	NeuroImage. Clinical	Montojo, C A; Congdon, E; Hwang, L; Jalbrzikowski, M; Kushan, L; Vesagas, T K; Jonas, R K; Ventura, J; Bilder, R M; Bearden, C E	January 1, 2015	Relevant
26201030	Create Study	Transcriptome Profiling of Peripheral Blood in 22q11.2 Deletion Syndrome Reveals Functional Pathways Related to Psychosis and Autism Spectrum Disorder.	PloS one	Jalbrzikowski, Maria; Lazaro, Maria T; Gao, Fuying; Huang, Alden; Chow, Carolyn; Geschwind, Daniel H; Coppola, Giovanni; Bearden, Carrie E	January 1, 2015	Relevant
25715178	Create Study	Cognitive decline preceding the onset of psychosis in patients with 22q11.2 deletion syndrome.	JAMA psychiatry	Vorstman, Jacob A S; Breetvelt, Elemi J; Duijff, Sasja N; Eliez, Stephan; Schneider, Maude; Jalbrzikowski, Maria; Armando, Marco; Vicari, Stefano; Shashi, Vandana; Hooper, Stephen R; Chow, Eva W C; Fung, Wai Lun Alan; Butcher, Nancy J; Young, Donald A; McDonald-McGinn, Donna M; Vogels, Annick; van Amelsvoort, Therese; Gothelf, Doron; Weinberger, Ronnie; Weizman, Abraham; Klaassen, Petra W J; Koops, Sanne; Kates, Wendy R; Antshel, Kevin M; Simon, Tony J; Ousley, Opal Y; Swillen, Ann; Gur, Raquel E; Bearden, Carrie E; Kahn, René S; Bassett, Anne S; International Consortium on Brain and Behavior in 22q11.2 Deletion Syndrome	April 2015	Relevant
24577245	Create Study	Psychiatric disorders from childhood to adulthood in 22q11.2 deletion syndrome: results from the International Consortium on Brain and Behavior in 22q11.2 Deletion Syndrome.	The American journal of psychiatry	Schneider, Maude; Debbané, Martin; Bassett, Anne S; Chow, Eva W C; Fung, Wai Lun Alan; van den Bree, Marianne; Owen, Michael; Murphy, Kieran C; Niarchou, Maria; Kates, Wendy R; Antshel, Kevin M; Fremont, Wanda; McDonald-McGinn, Donna M; Gur, Raquel E; Zackai, Elaine H; Vorstman, Jacob; Duijff, Sasja N; Klaassen, Petra W J; Swillen, Ann; Gothelf, Doron; Green, Tamar; Weizman, Abraham; Van Amelsvoort, Therese; Evers, Laurens; Boot, Erik; Shashi, Vandana; Hooper, Stephen R; Bearden, Carrie E; Jalbrzikowski, Maria; Armando, Marco; Vicari, Stefano; Murphy, Declan G; Ousley, Opal; Campbell, Linda E; Simon, Tony J; Eliez, Stephan; International Consortium on Brain and Behavior in 22q11.2 Deletion Syndrome	June 2014	Relevant
24567911	Create Study	Disrupted working memory circuitry and psychotic symptoms in 22q11.2 deletion syndrome.	NeuroImage. Clinical	Montojo CA, Ibrahim A, Karlsgodt KH, Chow C, Hilton AE, Jonas RK, Vesagas TK, Bearden CE	January 1, 2014	Relevant
24273724	Create Study	Structural abnormalities in cortical volume, thickness, and surface area in 22q11.2 microdeletion syndrome: Relationship with psychotic symptoms.	NeuroImage. Clinical	Jalbrzikowski, Maria; Jonas, Rachel; Senturk, Damla; Patel, Arati; Chow, Carolyn; Green, Michael F; Bearden, Carrie E	January 1, 2013	Relevant
24177988	Create Study	Neural substrates of inhibitory control deficits in 22q11.2 deletion syndrome.	Cerebral cortex (New York, N.Y. : 1991)	Montojo, C A; Jalbrzikowski, M; Congdon, E; Domicoli, S; Chow, C; Dawson, C; Karlsgodt, K H; Bilder, R M; Bearden, C E	April 2015	Relevant
23992925	Create Study	The 22q11.2 deletion syndrome as a window into complex neuropsychiatric disorders over the lifespan.	Biological psychiatry	Jonas, Rachel K; Montojo, Caroline A; Bearden, Carrie E	March 2014	Relevant
23912681	Create Study	Default mode network connectivity and reciprocal social behavior in 22q11.2 deletion syndrome.	Social cognitive and affective neuroscience	Schreiner MJ, Karlsgodt KH, Uddin LQ, Chow C, Congdon E, Jalbrzikowski M, Bearden CE	September 2014	Relevant
23453669	Create Study	Enhanced maternal origin of the 22q11.2 deletion in velocardiofacial and DiGeorge syndromes.	American journal of human genetics	Delio, Maria; Guo, Tingwei; McDonald-McGinn, Donna M; Zackai, Elaine; Herman, Sean; Kaminetzky, Mark; Higgins, Anne Marie; Coleman, Karlene; Chow, Carolyn; Jalbrzikowski, Maria; Jarlbrzkowski, Maria; Bearden, Carrie E; Bailey, Alice; Vangkilde, Anders; Olsen, Line; Olesen, Charlotte; Skovby, Flemming; Werge, Thomas M; Templin, Ludivine; Busa, Tiffany; Philip, Nicole; Swillen, Ann; Vermeesch, Joris R; Devriendt, Koen; Schneider, Maude; Dahoun, Sophie; Eliez, Stephan; Schoch, Kelly; Hooper, Stephen R; Shashi, Vandana; Samanich, Joy; Marion, Robert; van Amelsvoort, Therese; Boot, Erik; Klaassen, Petra; Duijff, Sasja N; Vorstman, Jacob; Yuen, Tracy; Silversides, Candice; Chow, Eva; Bassett, Anne; Frisch, Amos; Weizman, Abraham; Gothelf, Doron; Niarchou, Maria; van den Bree, Marianne; Owen, Michael J; Suñer, Damian Heine; Andreo, Jordi Rosell; Armando, Marco; Vicari, Stefano; Digilio, Maria Cristina; Auton, Adam; Kates, Wendy R; Wang, Tao; Shprintzen, Robert J; Emanuel, Beverly S; Morrow, Bernice E	March 2013	Relevant
23122739	Create Study	Social cognition in 22q11.2 microdeletion syndrome: relevance to psychosis?	Schizophrenia research	Jalbrzikowski, Maria; Carter, Chelsea; Senturk, Damla; Chow, Carolyn; Hopkins, Jessica M; Green, Michael F; Galván, Adriana; Cannon, Tyrone D; Bearden, Carrie E	December 2012	Relevant
23098994	Create Study	Converging levels of analysis on a genomic hotspot for psychosis: insights from 22q11.2 deletion syndrome.	Neuropharmacology	Schreiner, Matthew J; Lazaro, Maria T; Jalbrzikowski, Maria; Bearden, Carrie E	May 2013	Relevant
22962003	Create Study	Deficits in mental state attributions in individuals with 22q11.2 deletion syndrome (velo-cardio-facial syndrome).	Autism research : official journal of the International Society for Autism Research	Ho JS, Radoeva PD, Jalbrzikowski M, Chow C, Hopkins J, Tran WC, Mehta A, Enrique N, Gilbert C, Antshel KM, Fremont W, Kates WR, Bearden CE	December 2012	Relevant
21878355	Create Study	Genetic influence on the working memory circuitry: behavior, structure, function and extensions to illness.	Behavioural brain research	Karlsgodt KH, Bachman P, Winkler AM, Bearden CE, Glahn DC	December 2011	Relevant
21515140	Create Study	Clinical and genetic high-risk paradigms: converging paths to psychosis meet in the temporal lobes.	Biological psychiatry	Jalbrzikowski M, Bearden CE	May 2011	Relevant

helpcenter.collection.publications-tab

Collection - Publications

The number of Publications is displayed in parentheses next to the tab name. Clicking on any of the Publication Titles will open the Publication in a new internet browsing tab.

Collection Owners, Program Officers, and users with Submission or Administrative Privileges for the Collection may mark a publication as either Relevant or Not Relevant in the Status column.

Frequently Asked Questions

How can I determine if a publication is relevant?

Publications are considered relevant to a collection when the data shared is directly related to the project or collection.
Where does the NDA get the publications?

PubMed, an online library containing journals, articles, and medical research. Sponsored by NiH and National Library of Medicine (NLM).

Glossary

Create Study

A link to the Create an NDA Study page that can be clicked to start creating an NDA Study with information such as the title, journal and authors automatically populated.
Not Determined Publication

Indicates that the publication has not yet been reviewed and/or marked as Relevant or Not Relevant so it has not been determined whether an NDA Study is expected.
Not Relevant Publication

A publication that is not based on data related to the aims of the grant/project associated with the Collection or not based on any data such as a review article and, therefore, an NDA Study is not expected to be created.
PubMed

PubMed provides citation information for biomedical and life sciences publications and is managed by the U.S. National Institutes of Health's National Library of Medicine.
PubMed ID

The PUBMed ID is the unique ID number for the publication as recorded in the PubMed database.
Relevant Publication

A publication that is based on data related to the aims of the grant/project associated with the Collection and, therefore, an NDA Study is expected to be created.

Contact NDA Help Desk

Data Expected List: Mandatory Data Structures

These data structures are mandatory for your NDA Collection. Please update the Targeted Enrollment number to accurately represent the number of subjects you expect to submit for the entire study.

For NIMH HIV-related research that involves human research participants: Select the dictionary or dictionaries most appropriate for your research. If your research does not require all three data dictionaries, just ignore the ones you do not need. There is no need to delete extra data dictionaries from your NDA Collection. You can adjust the Targeted Enrollment column in the Data Expected tab to “0” for those unnecessary data dictionaries. At least one of the three data dictionaries must have a non-zero value.

Data Expected	Targeted Enrollment	Initial Submission	Subjects Submitted	Initial Share	Subjects Shared	Status
Research Subject and Pedigree	165	04/08/2019	0	04/08/2019	0	Approved

To create your project's Data Expected list, use the "+New Data Expected" to add or request existing structures and to request new Data Structures that are not in the NDA Data Dictionary.

If the Structure you need already exists, locate it and specify your dates and enrollment when adding it to your Data Expected list. If you require changes to the Structure you need, select the indicator stating "No, it requires changes to meet research needs," and upload a file containing your requested changes.

If the structure you need is not yet defined in the Data Dictionary, you can select "Upload Definition" and attach the necessary materials to request its creation.

When selecting the expected dates for your data, make sure to follow the standard Data Sharing Regimen and choose dates within the date ranges that correspond to your project start and end dates.

Please visit the Completing Your Data Expected Tutorial for more information.

Data Expected List: Data Structures per Research Aims

These data structures are specific to your research aims and should list all data structures in which data will be collected and submitted for this NDA Collection. Please update the Targeted Enrollment number to accurately represent the number of subjects you expect to submit for the entire study.

Data Expected	Targeted Enrollment	Initial Submission	Subjects Submitted	Initial Share	Subjects Shared	Status
ADOS	165	04/08/2019	0	04/08/2019	0	Approved
ADI-R	165	04/08/2019	0	04/08/2019	0	Approved
Social Responsiveness Scale (SRS)	165	06/01/2019	131	06/01/2019	94	Approved
Social Communication Questionnaire (SCQ)	165	04/08/2019	126	04/08/2019	20	Approved
Child Behavior Checklist (CBCL)	165	04/08/2019	124	04/08/2019	20	Approved
Tanner Sexual Maturity Scale	165	04/08/2019	124	04/08/2019	20	Approved
Screen for Childhood Anxiety Related Emotional Disorders (SCARED)	165	04/08/2019	127	04/08/2019	71	Approved
Structured Clinical Interview for DSM (SCID)	165	04/08/2019	72	04/08/2019	0	Approved
Daily Stress Inventory	165	10/01/2019	126	10/01/2019	20	Approved
Prodromal Questionnaire	165	04/08/2019	102	04/08/2019	2	Approved
Repetitive Behavior Scale - Revised (RBS-R)	165	04/08/2019	129	04/08/2019	71	Approved
Sensory Profile	165	04/08/2019	129	04/08/2019	71	Approved
Behavior Rating Inventory of Executive Function (BRIEF)	165	04/08/2019	115	04/08/2019	70	Approved
Brief Psychiatric Rating Scale	165	04/08/2019	128	04/08/2019	79	Approved
Structured Interview for Prodromal Syndromes/Scale of Prodromal Symptoms	165	04/08/2019	115	04/08/2019	95	Approved
Youth Self Report	165	04/08/2019	92	04/08/2019	38	Approved
Barratt Impulsivity Scale	165	04/08/2019	115	04/08/2019	20	Approved
Blood Sample Collection	165	04/08/2019	79	04/08/2019	0	Approved
Adult ADHD Self-Report Scale	165	04/08/2019	94	04/08/2019	37	Approved
Global Functioning Scales	165	04/08/2019	117	04/08/2019	1	Approved
Risk Beliefs Questionnaire	165	10/01/2019	118	10/01/2019	20	Approved

Structure not yet defined

No Status history for this Data Expected has been recorded yet

helpcenter.collection.data-expected-tab

Collection - Data Expected

The Data Expected tab displays the list of all data that NDA expects to receive in association with the Collection as defined by the contributing researcher, as well as the dates for the expected initial upload of the data, and when it is first expected to be shared, or with the research community. Above the primary table of Data Expected, any publications determined to be relevant to the data within the Collection are also displayed - members of the contributing research group can use these to define NDA Studies, connecting those papers to underlying data in NDA.

The tab is used both as a reference for those accessing shared data, providing information on what is expected and when it will be shared, and as the primary tracking mechanism for contributing projects. It is used by both contributing primary researchers, secondary researchers, and NIH Program and Grants Management staff.

Researchers who are starting their project need to update their Data Expected list to include all the Data Structures they are collecting under their grant and set their initial submission and sharing schedule according to the NDA Data Sharing Regimen.

To add existing Data Structures from the Data Dictionary, to request new Data Structure that are not in the Dictionary, or to request changes to existing Data Structures, click "+New Data Expected".

For step-by-step instructions on how to add existing Data Structures, request changes to an existing Structure, or request a new Data Structure, please visit the Completing Your Data Expected Tutorial.

If you are a contributing researcher creating this list for the first time, or making changes to the list as your project progress, please note the following:

Although items you add to the list and changes you make are displayed, they are not committed to the system until you Save the entire page using the "Save" button at the bottom of your screen. Please Save after every change to ensure none of your work is lost.
If you attempt to add a new structure, the title you provide must be unique - if another structure exists with the same name your change will fail.
Adding a new structure to this list is the only way to request the creation of a new Data Dictionary definition.

Frequently Asked Questions

What is an NDA Data Structure?

An NDA Data Structure is comprised of multiple Data Elements to make up an electronic definition of an assessment, measure, questionnaire, etc will have a corresponding Data Structure.
What is the NDA Data Dictionary?

The NDA Data Dictionary is comprised of electronic definitions known as Data Structures.

Glossary

Analyzed Data

Data specific to the primary aims of the research being conducted (e.g. outcome measures, other dependent variables, observations, laboratory results, analyzed images, volumetric data, etc.) including processed images.
Data Item

Items listed on the Data Expected list in the Collection which may be an individual and discrete Data Structure, Data Structure Category, or Data Structure Group.
Data Structure

A defined organization and group of Data Elements to represent an electronic definition of a measure, assessment, questionnaire, or collection of data points. Data structures that have been defined in the NDA Data Dictionary are available at https://nda.nih.gov/general-query.html?q=query=data-structure
Data Structure Category

An NDA term describing the affiliation of a Data Structure to a Category, which may be disease/disorder or diagnosis related (Depression, ADHD, Psychosis), specific to data type (MRI, eye tracking, omics), or type of data (physical exam, IQ).
Data Structure Group

A Data Item listed on the Data Expected tab of a Collection that indicates a group of Data Structures (e.g., ADOS or SCID) for which data may be submitted instead of a specific Data Structure identified by version, module, edition, etc. For example, the ADOS Data Structure Category includes every ADOS Data Structure such as ADOS Module 1, ADOS Module 2, ADOS Module 1 - 2nd Edition, etc. The SCID Data Structure Group includes every SCID Data Structure such as SCID Mania, SCID V Mania, SCID PTSD, SCID-V Diagnosis, and more.
Evaluated Data

A new Data Structure category, Evaluated Data is analyzed data resulting from the use of computational pipelines in the Cloud and can be uploaded directly back to a miNDAR database. Evaluated Data is expected to be listed as a Data Item in the Collection's Data Expected Tab.
Imaging Data

Imaging+ is an NDA term which encompasses all imaging related data including, but not limited to, images (DTI, MRI, PET, Structural, Spectroscopy, etc.) as well as neurosignal data (EEG, fMRI, MEG, EGG, eye tracking, etc.) and Evaluated Data.
Initial Share Date

Initial Submission and Initial Share dates should be populated according to the NDA Data Sharing Terms and Conditions. Any modifications to these will go through the approval processes outlined above. Data will be shared with authorized users upon publication (via an NDA Study) or 1-2 years after the grant end date specified on the first Notice of Award, as defined in the applicable Data Sharing Terms and Conditions.
Initial Submission Date

Initial Submission and Initial Share dates should be populated according to these NDA Data Sharing Terms and Conditions. Any modifications to these will go through the approval processes outlined above. Data for all subjects is not expected on the Initial Submission Date and modifications may be made as necessary based on the project's conduct.
Research Subject and Pedigree

An NDA created Data Structure used to convey basic information about the subject such as demographics, pedigree (links family GUIDs), diagnosis/phenotype, and sample location that are critical to allow for easier querying of shared data.
Submission Cycle

The NDA has two Submission Cycles per year - January 15 and July 15.
Submission Exemption

An interface to notify NDA that data may not be submitted during the upcoming/current submission cycle.

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Collection Owners and those with Collection Administrator permission, may edit a collection. The following is currently available for Edit on this page:

Associated Studies

Studies that have been defined using data from a Collection are important criteria to determine the value of data shared. The number of subjects column displays the counts from this Collection that are included in a Study, out of the total number of subjects in that study. The Data Use column represents whether or not the study is a primary analysis of the data or a secondary analysis. State indicates whether the study is private or shared with the research community.

Study NameFilter by Study Name	AbstractFilter by Abstract	Collection/Study SubjectsFilter by Collection/Study Subjects	Data UsageFilter by Data Usage	StateFilter by State
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Collection - Associated Studies

Clicking on the Study Title will open the study details in a new internet browser tab. The Abstract is available for viewing, providing the background explanation of the study, as provided by the Collection Owner.

Primary v. Secondary Analysis: The Data Usage column will have one of these two choices. An associated study that is listed as being used for Primary Analysis indicates at least some and potentially all of the data used was originally collected by the creator of the NDA Study. Secondary Analysis indicates the Study owner was not involved in the collection of data, and may be used as supporting data.

Private v. Shared State: Studies that remain private indicate the associated study is only available to users who are able to access the collection. A shared study is accessible to the general public.

Frequently Asked Questions

How do I associate a study to my collection?

Studies are associated to the Collection automatically when the data is defined in the Study.

Glossary

Associated Studies Tab

A tab in a Collection that lists the NDA Studies that have been created using data from that Collection including both Primary and Secondary Analysis NDA Studies.

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