NIMH Data Archive - Data

Genomics

Neuroimaging

Phenotype¹

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Clinical Trial

¹ Numbers reported are subjects by age

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Grant/Project Number

Format should be in the following format: Activity Code, Institute Abbreviation, and Serial Number. Grant Type, Support Year, and Suffix should be excluded. For example, grant 1R01MH123456-01A1 should be entered R01MH123456

Collection - Use Existing Experiment

To associate an experiment to the current collection, just select an axperiment from the table below then click the associate experiment button to persist your changes (saving the collection is not required). Note that once an experiment has been associated to two or more collections, the experiment will not longer be editable.

The table search feature is case insensitive and targets the experiment id, experiment name and experiment type columns. The experiment id is searched only when the search term entered is a number, and filtered using a startsWith comparison. When the search term is not numeric the experiment name is used to filter the results.

Select	Experiment Id	Experiment Name	Experiment Type	Created On

24	HI-NGS_R1	Omics	02/16/2011
475	MB1-10 (CHOP)	Omics	06/07/2016
490	Illumina Infinium PsychArray BeadChip Assay	Omics	07/07/2016
501	PharmacoBOLD Resting State	fMRI	07/27/2016
506	PVPREF	Omics	08/05/2016
509	ABC-CT Resting v2	EEG	08/18/2016
13	Comparison of FI expression in Autistic and Neurotypical Homo Sapiens	Omics	12/28/2010
18	AGRE/Broad Affymetrix 5.0 Genotype Experiment	Omics	01/06/2011
22	Stitching PCR Sequencing	Omics	02/14/2011
26	ASD_Methylation	Omics	03/01/2011
29	Microarray family 03 (father, mother, sibling)	Omics	03/24/2011
37	Standard paired-end sequencing of BCRs	Omics	04/19/2011
38	Illumina Mate-Pair BCR sequencing	Omics	04/19/2011
39	Custom Jumping Libraries	Omics	04/19/2011
40	Custom CapBP	Omics	04/19/2011
41	Immunofluorescence	Omics	05/11/2011
43	Autism brain sample genotyping, Illumina	Omics	05/16/2011
47	ARRA Autism Sequencing Collaboration at Baylor. SOLiD 4 System	Omics	08/01/2011
53	AGRE Omni1-quad	Omics	10/11/2011
59	AGP genotyping	Omics	04/03/2012
60	Ultradeep 454 sequencing of synaptic genes from postmortem cerebella of individuals with ASD and neurotypical controls	Omics	06/23/2012
63	Microemulsion PCR and Targeted Resequencing for Variant Detection in ASD	Omics	07/20/2012
76	Whole Genome Sequencing in Autism Families	Omics	01/03/2013
519	Resting	fMRI	11/08/2016
90	Genotyped IAN Samples	Omics	07/09/2013
91	NJLAGS Axiom Genotyping Array	Omics	07/16/2013
93	AGP genotyping (CNV)	Omics	09/06/2013
106	Longitudinal Sleep Study. H20 200. Channel set 2	EEG	11/07/2013
107	Longitudinal Sleep Study. H20 200. Channel set 3	EEG	11/07/2013
108	Longitudinal Sleep Study. AURA 200	EEG	11/07/2013
105	Longitudinal Sleep Study. H20 200. Channel set 1	EEG	11/07/2013
109	Longitudinal Sleep Study. AURA 400	EEG	11/07/2013
116	Gene Expression Analysis WG-6	Omics	01/07/2014
131	Jeste Lab UCLA ACEii: Charlie Brown and Sesame Street - Project 1	Eye Tracking	02/27/2014
132	Jeste Lab UCLA ACEii: Animacy - Project 1	Eye Tracking	02/27/2014
133	Jeste Lab UCLA ACEii: Mom Stranger - Project 2	Eye Tracking	02/27/2014
134	Jeste Lab UCLA ACEii: Face Emotion - Project 3	Eye Tracking	02/27/2014
145	AGRE/FMR1_Illumina.JHU	Omics	04/14/2014
146	AGRE/MECP2_Sanger.JHU	Omics	04/14/2014
147	AGRE/MECP2_Junior.JHU	Omics	04/14/2014
151	Candidate Gene Identification in familial Autism	Omics	06/09/2014
152	NJLAGS Whole Genome Sequencing	Omics	07/01/2014
154	Math Autism Study - Vinod Menon	fMRI	07/15/2014
155	Resting	fMRI	07/25/2014
156	Speech	fMRI	07/25/2014
159	Emotion	fMRI	07/25/2014
160	syllable contrast	EEG	07/29/2014
167	School-age naturalistic stimuli	Eye Tracking	09/19/2014
44	AGRE/Broad Affymetrix 5.0 Genotype Experiment	Omics	06/27/2011
45	Exome Sequencing of 20 Sporadic Cases of Autism Spectrum Disorder	Omics	07/15/2011

Collection - Add Experiment

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URL:

To add an existing Data Structure, enter its title in the search bar. If you need to request changes, select the indicator "No, it requires changes to meet research needs" after selecting the Structure, and upload the file with the request changes specific to the selected Data Structure. Your file should follow the Request Changes Procedure. If the Data Structure does not exist, select "Request New Data Structure" and upload the appropriate zip file.

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ADHD heterogeneity, mechanisms, and risk profile #3753

General
Experiments (0)
Shared Data
Publications (87)
Data Expected (29)
Associated Studies (0)

Collection Title	Collection Investigators	Collection Description
Collection Title:	ADHD heterogeneity, mechanisms, and risk profile
Collection Investigators:	Joel Nigg
Collection Description:	ADHD is defined by behavioral symptoms that are not well defined in relation to underlying neurobiology or mechanism. Using mechanisms to define its nosology and predict outcome is expected to be more powerful than the current approach, but this hope has not been realized. The current proposal seeks to break this impasse. It combines cognitive and emotion measures in a longitudinal design to establish a what mechanisms predict different outcomes, b whether novel, mechanism based types can be validated that will be useful to nosology and clinical practice, and c creation and cross validation of a clinical risk index that can directly translate mechanism knowledge into clinical practice. Although the rationale involves neurobiology to some extent, the measures are deliberately restricted to relatively low cost and easily disseminated measures that would readily be usable in clinical practice in a range of setting. A cohort of 486 children of which over 300 had well characterized ADHD at baseline will now be followed into adolescence in an accelerated longitudinal design. Over 2500 observations will be made across multiple waves and these will be used to characterize risk, recovery, and mechanisms. The project rationale and hypotheses derive from a detailed theoretical conception that the PI has developed over several years. The significance of the proposal derives from the potential to move ADHD mechanisms from theory to application both in nosology and clinical prediction. The innovation lies heavily in the proposal that mechanism based typology of ADHD is tractable and can be developed in a formal way. The approach will validate mechanism effects using a detailed longitudinal design that will enable strong evaluation of age and time invariance dependence of both typing models and effect sizes of their predictive utility. The age range studied childhood to middle adolescence is ideal for examining persistence desistance of ADHD as well as initiation of serious outcomes like drug use, health problems, and comorbid psychiatric disorders. Aim 1 will use a standard analytic strategy to evaluate mechanisms from a variable centered perspective. Aim 2 will use clustering validation approaches to explore the taxonomic possibilities of mechanism-based types and validate them over time. Aim 3 will introduce the risk score index to ADHD based on combining mechanisms and clinical features at different levels of analysis, with built in cross validation. The Aims directly match key priorities of the NIMH strategic plan. If successful, the project hopes to break the impasse facing the field with regard to utilizing mechanism-based concepts of ADHD in relation to taxonomy and clinical assessment.
Data Repository:	NIMH Data Archive
Permission Group:
Collection Creation Date:	11/19/2020
Collection Phase:	Funding Completed
Collection Sub-Phase:	Close Out
Blinded Clinical Trial:	No
Total Funded Amount:	$4,590,042.00
Subjects Shared:	2,525

{"values":[]}

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Funding Sources:

Funding Source Name	Funding Source URL
NIH - Extramural	None

Supporting Documentation:

Grant Information:

Project Number	Project Title	Start Date	End Date	Planned Enrollment	Actual Enrollment	Organization	Funds Obligated
R37MH059105-12	ADHD heterogeneity, mechanisms, and risk profile	02/17/2014	12/31/2023	424	392	OREGON HEALTH & SCIENCE UNIVERSITY	$4,590,042.00

Clinical Trials:

helpcenter.collection.general-tab

Collection - General Tab

Fields available for edit on the top portion of the page include:

Collection Title
Investigators
Collection Description
Collection Phase
Funding Source
Clinical Trials

Collection Phase: The current status of a research project submitting data to an NDA Collection, based on the timing of the award and/or the data that have been submitted.

Pre-Enrollment: The default entry made when the NDA Collection is created.
Enrolling: Data have been submitted to the NDA Collection or the NDA Data Expected initial submission date has been reached for at least one data structure category in the NDA Collection.
Data Analysis: Subject level data collection for the research project is completed and has been submitted to the NDA Collection. The NDA Collection owner or the NDA Help Desk may set this phase when they’ve confirmed data submission is complete and submitted subject counts match at least 90% of the target enrollment numbers in the NDA Data Expected. Data submission reminders will be turned off for the NDA Collection.
Funding Completed: The NIH grant award (or awards) associated with the NDA Collection has reached its end date. NDA Collections in Funding Completed phase are assigned a subphase to indicate the status of data submission.
- The Data Expected Subphase indicates that NDA expects more data will be submitted
- The Closeout Subphase indicates the data submission is complete.
- The Sharing Not Met Subphase indicates that data submission was not completed as expected.

Blinded Clinical Trial Status:

This status is set by a Collection Owner and indicates the research project is a double blinded clinical trial. When selected, the public view of Data Expected will show the Data Expected items and the Submission Dates, but the targeted enrollment and subjects submitted counts will not be displayed.
Targeted enrollment and subjects submitted counts are visible only to NDA Administrators and to the NDA Collection or as the NDA Collection Owner.
When an NDA Collection that is flagged Blinded Clinical Trial reaches the maximum data sharing date for that Data Repository (see https://nda.nih.gov/nda/sharing-regimen.html), the embargo on Data Expected information is released.

Funding Source

The organization(s) responsible for providing the funding is listed here.

Supporting Documentation

Users with Submission privileges, as well as Collection Owners, Program Officers, and those with Administrator privileges, may upload and attach supporting documentation. By default, supporting documentation is shared to the general public, however, the option is also available to limit this information to qualified researchers only.

Grant Information

Identifiable details are displayed about the Project of which the Collection was derived from. You may click in the Project Number to view a full report of the Project captured by the NIH.

Clinical Trials

Any data that is collected to support or further the research of clinical studies will be available here. Collection Owners and those with Administrator privileges may add new clinical trials.

Frequently Asked Questions

How does the NIMH Data Archive (NDA) determine which Permission Group data are submitted into?

During Collection creation, NDA staff determine the appropriate Permission Group based on the type of data to be submitted, the type of access that will be available to data access users, and the information provided by the Program Officer during grant award.
How do I know when a NDA Collection has been created?

When a Collection is created by NDA staff, an email notification will automatically be sent to the PI(s) of the grant(s) associated with the Collection to notify them.
Is a single grant number ever associated with more than one Collection?

The NDA system does not allow for a single grant to be associated with more than one Collection; therefore, a single grant will not be listed in the Grant Information section of a Collection for more than one Collection.
Why is there sometimes more than one grant included in a Collection?

In general, each Collection is associated with only one grant; however, multiple grants may be associated if the grant has multiple competing segments for the same grant number or if multiple different grants are all working on the same project and it makes sense to hold the data in one Collection (e.g., Cooperative Agreements).

Glossary

Administrator Privilege

A privilege provided to a user associated with an NDA Collection or NDA Study whereby that user can perform a full range of actions including providing privileges to other users.
Collection Owner

Generally, the Collection Owner is the contact PI listed on a grant. Only one NDA user is listed as the Collection owner. Most automated emails are primarily sent to the Collection Owner.
Collection Phase
The Collection Phase provides information on data submission as opposed to grant/project completion so while the Collection phase and grant/project phase may be closely related they are often different. Collection users with Administrative Privileges are encouraged to edit the Collection Phase. The Program Officer as listed in eRA (for NIH funded grants) may also edit this field. Changes must be saved by clicking the Save button at the bottom of the page. This field is sortable alphabetically in ascending or descending order. Collection Phase options include:
- Pre-Enrollment: A grant/project has started, but has not yet enrolled subjects.
- Enrolling: A grant/project has begun enrolling subjects. Data submission is likely ongoing at this point.
- Data Analysis: A grant/project has completed enrolling subjects and has completed all data submissions.
- Funding Completed: A grant/project has reached the project end date.
Collection Title

An editable field with the title of the Collection, which is often the title of the grant associated with the Collection.
Grant

Provides the grant number(s) for the grant(s) associated with the Collection. The field is a hyperlink so clicking on the Grant number will direct the user to the grant information in the NIH Research Portfolio Online Reporting Tools (RePORT) page.
Supporting Documentation

Various documents and materials to enable efficient use of the data by investigators unfamiliar with the project and may include the research protocol, questionnaires, and study manuals.
NIH Research Initiative

NDA Collections may be organized by scientific similarity into NIH Research Initiatives, to facilitate query tool user experience. NIH Research Initiatives map to one or multiple Funding Opportunity Announcements.
Permission Group

Access to shared record-level data in NDA is provisioned at the level of a Permission Group. NDA Permission Groups consist of one or multiple NDA Collections that contain data with the same subject consents.
Planned Enrollment

Number of human subject participants to be enrolled in an NIH-funded clinical research study. The data is provided in competing applications and annual progress reports.
Actual Enrollment

Number of human subjects enrolled in an NIH-funded clinical research study. The data is provided in annual progress reports.
NDA Collection

A virtual container and organization structure for data and associated documentation from one grant or one large project/consortium. It contains tools for tracking data submission and allows investigators to define a wide array of other elements that provide context for the data, including all general information regarding the data and source project, experimental parameters used to collect any event-based data contained in the Collection, methods, and other supporting documentation. They also allow investigators to link underlying data to an NDA Study, defining populations and subpopulations specific to research aims.
Data Use Limitations

Data Use Limitations (DULs) describe the appropriate secondary use of a dataset and are based on the original informed consent of a research participant. NDA only accepts consent-based data use limitations defined by the NIH Office of Science Policy.
Total Subjects Shared

The total number of unique subjects for whom data have been shared and are available for users with permission to access data.

Contact NDA Help Desk

ID	Name	Created Date	Status	Type
No records found.

helpcenter.collection.experiments-tab

Collection - Experiments

The number of Experiments included is displayed in parentheses next to the tab name. You may download all experiments associated with the Collection via the Download button. You may view individual experiments by clicking the Experiment Name and add them to the Filter Cart via the Add to Cart button.

Collection Owners, Program Officers, and users with Submission or Administrative Privileges for the Collection may create or edit an Experiment.

Please note: The creation of an NDA Experiment does not necessarily mean that data collected, according to the defined Experiment, has been submitted or shared.

Frequently Asked Questions

Can an Experiment be associated with more than one Collection?
Yes -see the “Copy” button in the bottom left when viewing an experiment. There are two actions that can be performed via this button:
1. Copy the experiment with intent for modifications.
2. Associate the experiment to the collection. No modifications can be made to the experiment.

Glossary

Experiment Status

An Experiment must be Approved before data using the associated Experiment_ID may be uploaded.
Experiment ID

The ID number automatically generated by NDA which must be included in the appropriate file when uploading data to link the Experiment Definition to the subject record.

Contact NDA Help Desk

Shared Data:

Title	Type	Number of Subjects
ADHD Rating Scale	Clinical Assessments	1084
Alabama Parenting Questionnaire	Clinical Assessments	915
BASC Self Report Adolescent	Clinical Assessments	364
Child Behavior Checklist (CBCL) 6-18	Clinical Assessments	926
Child Depression Inventory (CDI)	Clinical Assessments	832
Children's Perception of Interparental Conflict Scale	Clinical Assessments	1022
Color Reading Interference (Stroop)	Clinical Assessments	594
Common Language Q-Sort	Clinical Assessments	853
Conners Parent Rating Scales Revised Short 1997	Clinical Assessments	1303
Conners-Wells Self-Report Scale	Clinical Assessments	361
Delis-Kaplan Executive Function System	Clinical Assessments	496
Early Adolescent Temperament Questionnaire	Clinical Assessments	725
Family Environment Scale	Clinical Assessments	493
Multidimensional Anxiety Scale for Children Parent and Self	Clinical Assessments	954
O'Leary Porter Scale	Clinical Assessments	770
Research Subject	Clinical Assessments	2525
Strengths and Weakness of ADHD Symptoms and Normal Behavior	Clinical Assessments	877
Wechsler Adult Intelligence Scale III	Clinical Assessments	791
Wechsler Individual Achievement Test Second Edition	Clinical Assessments	1111
Wechsler Intelligence Scale for Children - IV [part 1]	Clinical Assessments	552
Wechsler Intelligence Scale for Children - IV [part 2]	Clinical Assessments	785
Wechsler Intelligence Scale for Children III	Clinical Assessments	878
Wide Range Achievement Test 3 (WRAT3)	Clinical Assessments	238
Woodcock Johnson Tests of Cognitive Abilities and Tests of Achievement	Clinical Assessments	1147
Youth Self Report	Clinical Assessments	1078

helpcenter.collection.shared-data-tab

Collection - Shared Data

This tab provides a quick overview of the Data Structure title, Data Type, and Number of Subjects that are currently Shared for the Collection. The information presented in this tab is automatically generated by NDA and cannot be edited. If no information is visible on this tab, this would indicate the Collection does not have shared data or the data is private.

The shared data is available to other researchers who have permission to access data in the Collection's designated Permission Group(s). Use the Download button to get all shared data from the Collection to the Filter Cart.

Frequently Asked Questions

How will I know if another researcher uses data that I shared through the NIMH Data Archive (NDA)?

To see what data your project have submitted are being used by a study, simply go the Associated Studies tab of your collection. Alternatively, you may review an NDA Study Attribution Report available on the General tab.
Can I get a supplement to share data from a completed research project?

Often it becomes more difficult to organize and format data electronically after the project has been completed and the information needed to create a GUID may not be available; however, you may still contact a program staff member at the appropriate funding institution for more information.
Can I get a supplement to share data from a research project that is still ongoing?

Unlike completed projects where researchers may not have the information needed to create a GUID and/or where the effort needed to organize and format data becomes prohibitive, ongoing projects have more of an opportunity to overcome these challenges. Please contact a program staff member at the appropriate funding institution for more information.

Glossary

Data Structure

A defined organization and group of Data Elements to represent an electronic definition of a measure, assessment, questionnaire, or collection of data points. Data structures that have been defined in the NDA Data Dictionary are available at https://nda.nih.gov/general-query.html?q=query=data-structure
Data Type

A grouping of data by similar characteristics such as Clinical Assessments, Omics, or Neurosignal data.
Shared

The term 'Shared' generally means available to others; however, there are some slightly different meanings based on what is Shared. A Shared NDA Study is viewable and searchable publicly regardless of the user's role or whether the user has an NDA account. A Shared NDA Study does not necessarily mean that data used in the NDA Study have been shared as this is independently determined. Data are shared according the schedule defined in a Collection's Data Expected Tab and/or in accordance with data sharing expectations in the NDA Data Sharing Terms and Conditions. Additionally, Supporting Documentation uploaded to a Collection may be shared independent of whether data are shared.

Contact NDA Help Desk

Collection Owners and those with Collection Administrator permission, may edit a collection. The following is currently available for Edit on this page:

Publications

Publications relevant to NDA data are listed below. Most displayed publications have been associated with the grant within Pubmed. Use the "+ New Publication" button to add new publications. Publications relevant/not relevant to data expected are categorized. Relevant publications are then linked to the underlying data by selecting the Create Study link. Study provides the ability to define cohorts, assign subjects, define outcome measures and lists the study type, data analysis and results. Analyzed data and results are expected in this way.

PubMed ID	Study	Title	Journal	Authors	Date	Status
37843650	Create Study	The Relationship Between Emotion Dysregulation and Error Monitoring in Adolescents with ADHD.	Research on child and adolescent psychopathology	Figuracion, McKenzie T; Kozlowski, Michael B; Macknyk, Katelyn S; Heise, Madelyn B; Pieper, Sarah M; Alperin, Brittany R; Morton, Hannah E; Nigg, Joel T; Karalunas, Sarah L	April 1, 2024	Not Determined
37205171	Create Study	Prediction of Attention-Deficit/Hyperactivity Disorder Diagnosis Using Brief, Low-Cost Clinical Measures: A Competitive Model Evaluation.	Clinical psychological science : a journal of the Association for Psychological Science	Mooney, Michael A; Neighbor, Christopher; Karalunas, Sarah; Dieckmann, Nathan F; Nikolas, Molly; Nousen, Elizabeth; Tipsord, Jessica; Song, Xubo; Nigg, Joel T	May 1, 2023	Not Determined
37126061	Create Study	Considerations toward an epigenetic and common pathways theory of mental disorder.	Journal of psychopathology and clinical science	Nigg, Joel T	April 1, 2023	Not Determined
36934605	Create Study	Polyneuro risk scores capture widely distributed connectivity patterns of cognition.	Developmental cognitive neuroscience	Byington, Nora; Grimsrud, Gracie; Mooney, Michael A; Cordova, Michaela; Doyle, Olivia; Hermosillo, Robert J M; Earl, Eric; Houghton, Audrey; Conan, Gregory; Hendrickson, Timothy J; Ragothaman, Anjanibhargavi; Carrasco, Cristian Morales; Rueter, Amanda; Perrone, Anders; Moore, Lucille A; Graham, Alice; Nigg, Joel T; Thompson, Wesley K; Nelson, Steven M; Feczko, Eric; Fair, Damien A; Miranda-Dominguez, Oscar	April 1, 2023	Not Determined
36817187	Create Study	Attention-deficit/hyperactivity disorder and white matter microstructure: the importance of dimensional analyses and sex differences.	JCPP advances	Jones, Scott A; Nagel, Bonnie J; Nigg, Joel T; Karalunas, Sarah L	December 1, 2022	Not Determined
36804107	Create Study	A preliminary study of white matter correlates of a laboratory measure of attention and motor stability in attention-deficit/hyperactivity disorder.	Journal of psychiatric research	Jones, Scott A; Tipsord, Jessica; Nagel, Bonnie J; Nigg, Joel T	April 1, 2023	Not Determined
36795263	Create Study	Gene-by-Environment Interaction Effects of Social Adversity on Externalizing Behavior in ABCD Youth.	Behavior genetics	Dash, Genevieve F; Karalunas, Sarah L; Kenyon, Emily A; Carter, Emily K; Mooney, Michael A; Nigg, Joel T; Feldstein Ewing, Sarah W	May 1, 2023	Not Determined
36656406	Create Study	Data-Driven Methods for Predicting ADHD Diagnosis and Related Impairment: The Potential of a Machine Learning Approach.	Research on child and adolescent psychopathology	Goh, Patrick K; Elkins, Anjeli R; Bansal, Pevitr S; Eng, Ashley G; Martel, Michelle M	May 1, 2023	Not Determined
36645612	Create Study	Youth Polygenic Scores, Youth ADHD Symptoms, and Parenting Dimensions: An Evocative Gene-Environment Correlation Study.	Research on child and adolescent psychopathology	de la Paz, Leiana; Mooney, Michael A; Ryabinin, Peter; Neighbor, Christopher; Antovich, Dylan; Nigg, Joel T; Nikolas, Molly A	May 1, 2023	Not Determined
36545360	Create Study	Early manifestations of genetic liability for ADHD, autism and schizophrenia at ages 18 and 24 months.	JCPP advances	Riglin, Lucy; Tobarra-Sanchez, Esther; Stergiakouli, Evie; Havdahl, Alexandra; Tilling, Kate; O'Donovan, Michael; Nigg, Joel; Langley, Kate; Thapar, Anita	September 1, 2022	Not Determined
36464786	Create Study	Prospective prediction of developing internalizing disorders in ADHD.	Journal of child psychology and psychiatry, and allied disciplines	Karalunas, Sarah L; Antovich, Dylan; Miller, Natalie; Nigg, Joel T	May 1, 2023	Not Determined
36238202	Create Study	Early development of negative and positive affect: Implications for ADHD symptomatology across three birth cohorts.	Development and psychopathology	Gustafsson, Hanna C; Nolvi, Saara; Sullivan, Elinor L; Rasmussen, Jerod M; Gyllenhammer, Lauren E; Entringer, Sonja; Wadhwa, Pathik D; O'Connor, Thomas G; Karlsson, Linnea; Karlsson, Hasse; Korja, Riikka; Buss, Claudia; Graham, Alice M; Nigg, Joel T	December 1, 2021	Not Determined
36220605	Create Study	Annual Research Review: Perspectives on progress in ADHD science - from characterization to cause.	Journal of child psychology and psychiatry, and allied disciplines	Sonuga-Barke, Edmund J S; Becker, Stephen P; Bölte, Sven; Castellanos, Francisco Xavier; Franke, Barbara; Newcorn, Jeffrey H; Nigg, Joel T; Rohde, Luis Augusto; Simonoff, Emily	April 1, 2023	Not Determined
36188231	Create Study	Parsing ADHD with Temperament Traits.	Current directions in psychological science	Nigg, Joel	August 1, 2022	Not Determined
36174168	Create Study	Temperament in middle childhood questionnaire: New data on factor structure and applicability in a child clinical sample.	Psychological assessment	Kozlowski, Michael B; Antovich, Dylan; Karalunas, Sarah L; Nigg, Joel T	December 1, 2022	Not Determined
35933504	Create Study	Epigenetics and ADHD: Reflections on Current Knowledge, Research Priorities and Translational Potential.	Molecular diagnosis & therapy	Cecil, Charlotte A M; Nigg, Joel T	November 1, 2022	Not Determined
35427730	Create Study	Attention-Deficit/Hyperactivity Disorder: Restricted Phenotypes Prevalence, Comorbidity, and Polygenic Risk Sensitivity in the ABCD Baseline Cohort.	Journal of the American Academy of Child and Adolescent Psychiatry	Cordova, Michaela M; Antovich, Dylan M; Ryabinin, Peter; Neighbor, Christopher; Mooney, Michael A; Dieckmann, Nathan F; Miranda-Dominguez, Oscar; Nagel, Bonnie J; Fair, Damien A; Nigg, Joel T	October 1, 2022	Not Determined
35312046	Create Study	Electroencephalogram aperiodic power spectral slope can be reliably measured and predicts ADHD risk in early development.	Developmental psychobiology	Karalunas, Sarah L; Ostlund, Brendan D; Alperin, Brittany R; Figuracion, McKenzie; Gustafsson, Hanna C; Deming, Erika Michiko; Foti, Dan; Antovich, Dylan; Dude, Jason; Nigg, Joel; Sullivan, Elinor	April 1, 2022	Not Determined
35210712	Create Study	Longitudinal network model of the co-development of temperament, executive functioning, and psychopathology symptoms in youth with and without ADHD.	Development and psychopathology	Karalunas, Sarah L; Antovich, Dylan; Goh, Patrick K; Martel, Michelle M; Tipsord, Jessica; Nousen, Elizabeth K; Nigg, Joel T	December 1, 2021	Not Determined
35102487	Create Study	Longitudinal Temperament Pathways to ADHD Between Childhood and Adolescence.	Research on child and adolescent psychopathology	Martel, Michelle M; Elkins, Anjeli R; Eng, Ashley G; Goh, Patrick K; Bansal, Pevitr S; Smith-Thomas, Tess E; Thaxton, Melina H; Ryabinin, Peter; Mooney, Michael A; Gustafsson, Hanna C; Karalunas, Sarah L; Nigg, Joel T	August 1, 2022	Not Determined
34472891	Create Study	Longitudinal attention-deficit/hyperactivity disorder symptom networks in childhood and adolescence: Key symptoms, stability, and predictive validity.	Journal of abnormal psychology	Martel, Michelle M; Goh, Patrick K; Lee, Christine A; Karalunas, Sarah L; Nigg, Joel T	July 1, 2021	Not Determined
34368774	Create Study	Development of ADHD: Etiology, Heterogeneity, and Early Life Course.	Annual review of developmental psychology	Nigg, Joel T; Sibley, Margaret H; Thapar, Anita; Karalunas, Sarah L	December 1, 2020	Not Determined
34348521	Create Study	Etiological Networks of Attention-Deficit/Hyperactivity Disorder during Childhood and Adolescence.	Journal of clinical child and adolescent psychology : the official journal for the Society of Clinical Child and Adolescent Psychology, American Psychological Association, Division 53	Goh, Patrick K; Smith, Tess E; Lee, Christine A; Bansal, Pevitr S; Eng, Ashley G; Martel, Michelle M	January 1, 2023	Not Determined
33549739	Create Study	The World Federation of ADHD International Consensus Statement: 208 Evidence-based conclusions about the disorder.	Neuroscience and biobehavioral reviews	Faraone, Stephen V; Banaschewski, Tobias; Coghill, David; Zheng, Yi; Biederman, Joseph; Bellgrove, Mark A; Newcorn, Jeffrey H; Gignac, Martin; Al Saud, Nouf M; Manor, Iris; Rohde, Luis Augusto; Yang, Li; Cortese, Samuele; Almagor, Doron; Stein, Mark A; Albatti, Turki H; Aljoudi, Haya F; Alqahtani, Mohammed M J; Asherson, Philip; Atwoli, Lukoye; Bölte, Sven; Buitelaar, Jan K; Crunelle, Cleo L; Daley, David; Dalsgaard, Søren; Döpfner, Manfred; Espinet, Stacey; Fitzgerald, Michael; Franke, Barbara; Gerlach, Manfred; Haavik, Jan; Hartman, Catharina A; Hartung, Cynthia M; Hinshaw, Stephen P; Hoekstra, Pieter J; Hollis, Chris; Kollins, Scott H; Sandra Kooij, J J; Kuntsi, Jonna; Larsson, Henrik; Li, Tingyu; Liu, Jing; Merzon, Eugene; Mattingly, Gregory; Mattos, Paulo; McCarthy, Suzanne; Mikami, Amori Yee; Molina, Brooke S G; Nigg, Joel T; Purper-Ouakil, Diane; Omigbodun, Olayinka O; Polanczyk, Guilherme V; Pollak, Yehuda; Poulton, Alison S; Rajkumar, Ravi Philip; Reding, Andrew; Reif, Andreas; Rubia, Katya; Rucklidge, Julia; Romanos, Marcel; Ramos-Quiroga, J Antoni; Schellekens, Arnt; Scheres, Anouk; Schoeman, Renata; Schweitzer, Julie B; Shah, Henal; Solanto, Mary V; Sonuga-Barke, Edmund; Soutullo, César; Steinhausen, Hans-Christoph; Swanson, James M; Thapar, Anita; Tripp, Gail; van de Glind, Geurt; van den Brink, Wim; Van der Oord, Saskia; Venter, Andre; Vitiello, Benedetto; Walitza, Susanne; Wang, Yufeng	September 1, 2021	Not Determined
33535138	Create Study	Behavioral and cognitive correlates of the aperiodic (1/f-like) exponent of the EEG power spectrum in adolescents with and without ADHD.	Developmental cognitive neuroscience	Ostlund, Brendan D; Alperin, Brittany R; Drew, Trafton; Karalunas, Sarah L	April 1, 2021	Not Determined
33534092	Create Study	Evaluating the Viability of Neurocognition as a Transdiagnostic Construct Using Both Latent Variable Models and Network Analysis.	Research on child and adolescent psychopathology	Eadeh, Hana-May; Markon, Kristian E; Nigg, Joel T; Nikolas, Molly A	June 1, 2021	Not Determined
33521326	Create Study	Effort-Related Decision-Making in ADHD.	Journal of psychiatry and brain science	Mitchell, Suzanne H; Sevigny-Resetco, Deborah	January 1, 2020	Not Determined
33365203	Create Study	Classroom-Based Mindfulness Training Reduces Anxiety in Adolescents: Acceptability and Effectiveness of a Cluster-Randomized Pilot Study.	Journal of restorative medicine	Johnstone, Jeanette M; Ribbers, Amanda; Jenkins, David; Atchley, Rachel; Gustafsson, Hanna; Nigg, Joel T; Wahbeh, Helané; Oken, Barry	January 1, 2020	Not Determined
32707260	Create Study	Evaluation of maternal inflammation as a marker of future offspring ADHD symptoms: A prospective investigation.	Brain, behavior, and immunity	Gustafsson, Hanna C; Sullivan, Elinor L; Battison, Eleanor A J; Holton, Kathleen F; Graham, Alice M; Karalunas, Sarah L; Fair, Damien A; Loftis, Jennifer M; Nigg, Joel T	October 1, 2020	Not Determined
32666315	Create Study	Subgroups of Childhood ADHD Based on Temperament Traits and Cognition: Concurrent and Predictive Validity.	Journal of abnormal child psychology	Goh, Patrick K; Lee, Christine A; Martel, Michelle M; Karalunas, Sarah L; Nigg, Joel T	October 1, 2020	Not Determined
32305325	Create Study	Toward a Revised Nosology for Attention-Deficit/Hyperactivity Disorder Heterogeneity.	Biological psychiatry. Cognitive neuroscience and neuroimaging	Nigg, Joel T; Karalunas, Sarah L; Feczko, Eric; Fair, Damien A	August 1, 2020	Not Determined
32217469	Create Study	Heterogeneity of executive function revealed by a functional random forest approach across ADHD and ASD.	NeuroImage. Clinical	Cordova, Michaela; Shada, Kiryl; Demeter, Damion V; Doyle, Olivia; Miranda-Dominguez, Oscar; Perrone, Anders; Schifsky, Emma; Graham, Alice; Fombonne, Eric; Langhorst, Beth; Nigg, Joel; Fair, Damien A; Feczko, Eric	January 1, 2020	Not Determined
32198002	Create Study	Emotion-Cognition Interactions in Attention-Deficit/Hyperactivity Disorder: Increased Early Attention Capture and Weakened Attentional Control in Emotional Contexts.	Biological psychiatry. Cognitive neuroscience and neuroimaging	Karalunas, Sarah L; Weigard, Alexander; Alperin, Brittany	May 1, 2020	Not Determined
32033925	Create Study	Polygenic Risk Score-Derived Subcortical Connectivity Mediates Attention-Deficit/Hyperactivity Disorder Diagnosis.	Biological psychiatry. Cognitive neuroscience and neuroimaging	Hermosillo, Robert J M; Mooney, Michael A; Fezcko, Eric; Earl, Eric; Marr, Mollie; Sturgeon, Darrick; Perrone, Anders; Dominguez, Oscar Miranda; Faraone, Stephen V; Wilmot, Beth; Nigg, Joel T; Fair, Damien A	March 1, 2020	Not Determined
31924323	Create Study	Heterogeneity and Subtyping in Attention-Deficit/Hyperactivity Disorder-Considerations for Emerging Research Using Person-Centered Computational Approaches.	Biological psychiatry	Karalunas, Sarah L; Nigg, Joel T	July 1, 2020	Not Determined
31605387	Create Study	Evaluating chronic emotional dysregulation and irritability in relation to ADHD and depression genetic risk in children with ADHD.	Journal of child psychology and psychiatry, and allied disciplines	Nigg, Joel T; Karalunas, Sarah L; Gustafsson, Hanna C; Bhatt, Priya; Ryabinin, Peter; Mooney, Michael A; Faraone, Stephen V; Fair, Damien A; Wilmot, Beth	February 1, 2020	Not Determined
31233897	Create Study	The relationship between alpha asymmetry and ADHD depends on negative affect level and parenting practices.	Journal of psychiatric research	Alperin, Brittany R; Smith, Christiana J; Gustafsson, Hanna C; Figuracion, McKenzie T; Karalunas, Sarah L	September 1, 2019	Not Determined
31153774	Create Study	The Heterogeneity Problem: Approaches to Identify Psychiatric Subtypes.	Trends in cognitive sciences	Feczko, Eric; Miranda-Dominguez, Oscar; Marr, Mollie; Graham, Alice M; Nigg, Joel T; Fair, Damien A	July 1, 2019	Not Determined
31103523	Create Study	Neuroinflammation as a risk factor for attention deficit hyperactivity disorder.	Pharmacology, biochemistry, and behavior	Dunn, Geoffrey A; Nigg, Joel T; Sullivan, Elinor L	July 1, 2019	Not Determined
30652912	Create Study	Child and adolescent predictors of smoking involvement in emerging adulthood.	Health psychology : official journal of the Division of Health Psychology, American Psychological Association	Jester, Jennifer M; Glass, Jennifer M; Bohnert, Kipling M; Nigg, Joel T; Wong, Maria M; Zucker, Robert A	February 1, 2019	Not Determined
30535156	Create Study	Sibling Recurrence Risk and Cross-aggregation of Attention-Deficit/Hyperactivity Disorder and Autism Spectrum Disorder.	JAMA pediatrics	Miller, Meghan; Musser, Erica D; Young, Gregory S; Olson, Brent; Steiner, Robert D; Nigg, Joel T	February 1, 2019	Not Determined
30386005	Create Study	Working memory mediates increased negative affect and suicidal ideation in childhood attention-deficit/hyperactivity disorder.	Journal of psychopathology and behavioral assessment	Bauer, Brian W; Gustafsson, Hanna C; Nigg, Joel; Karalunas, Sarah L	June 1, 2018	Not Determined
30359050	Create Study	Do we need an irritable subtype of ADHD? Replication and extension of a promising temperament profile approach to ADHD subtyping.	Psychological assessment	Karalunas, Sarah L; Gustafsson, Hanna C; Fair, Damien; Musser, Erica D; Nigg, Joel T	February 1, 2019	Not Determined
30264639	Create Study	Addressing Discrepancies Between ADHD Prevalence and Case Identification Estimates Among U.S. Children Utilizing NSCH 2007-2012.	Journal of attention disorders	Song, MinKyoung; Dieckmann, Nathan F; Nigg, Joel T	December 1, 2019	Not Determined
30215033	Create Study	ADHD and attentional control: Impaired segregation of task positive and task negative brain networks.	Network neuroscience (Cambridge, Mass.)	Mills, Brian D; Miranda-Dominguez, Oscar; Mills, Kathryn L; Earl, Eric; Cordova, Michaela; Painter, Julia; Karalunas, Sarah L; Nigg, Joel T; Fair, Damien A	January 1, 2018	Not Determined
29920327	Create Study	Maternal prenatal depression predicts infant negative affect via maternal inflammatory cytokine levels.	Brain, behavior, and immunity	Gustafsson, Hanna C; Sullivan, Elinor L; Nousen, Elizabeth K; Sullivan, Ceri A; Huang, Elaine; Rincon, Monica; Nigg, Joel T; Loftis, Jennifer M	October 1, 2018	Not Determined
29799950	Create Study	Toward an Emerging Paradigm for Understanding Attention-Deficit/Hyperactivity Disorder and Other Neurodevelopmental, Mental, and Behavioral Disorders: Environmental Risks and Epigenetic Associations.	JAMA pediatrics	Nigg, Joel T	July 1, 2018	Not Determined
29496126	Create Study	Working Memory and Vigilance as Multivariate Endophenotypes Related to Common Genetic Risk for Attention-Deficit/Hyperactivity Disorder.	Journal of the American Academy of Child and Adolescent Psychiatry	Nigg, Joel T; Gustafsson, Hanna C; Karalunas, Sarah L; Ryabinin, Peter; McWeeney, Shannon K; Faraone, Stephen V; Mooney, Michael A; Fair, Damien A; Wilmot, Beth	March 1, 2018	Not Determined
29494860	Create Study	Sleep and behavioral control in earlier life predicted resilience in young adulthood: A prospective study of children of alcoholics and controls.	Addictive behaviors	Wong, Maria M; Puttler, Leon I; Nigg, Joel T; Zucker, Robert A	July 1, 2018	Not Determined
29450820	Create Study	Overlapping and Distinct Cognitive Impairments in Attention-Deficit/Hyperactivity and Autism Spectrum Disorder without Intellectual Disability.	Journal of abnormal child psychology	Karalunas, Sarah L; Hawkey, Elizabeth; Gustafsson, Hanna; Miller, Meghan; Langhorst, Marybeth; Cordova, Michaela; Fair, Damien; Nigg, Joel T	November 1, 2018	Not Determined
29361884	Create Study	Evaluation of dietary intake in children and college students with and without attention-deficit/hyperactivity disorder.	Nutritional neuroscience	Holton, Kathleen F; Johnstone, Jeanette M; Brandley, Elizabeth T; Nigg, Joel T	September 1, 2019	Not Determined
29128953	Create Study	Is the Association of ADHD with Socio-Economic Disadvantage Explained by Child Comorbid Externalizing Problems or Parent ADHD?	Journal of abnormal child psychology	Miller, Lindsay L; Gustafsson, Hanna C; Tipsord, Jessica; Song, Minkyoung; Nousen, Elizabeth; Dieckmann, Nathan; Nigg, Joel T	July 1, 2018	Not Determined
29106272	Create Study	Concurrent and developmental correlates of psychopathic traits using a triarchic psychopathy model approach.	Journal of abnormal psychology	Dotterer, Hailey L; Waller, Rebecca; Cope, Lora M; Hicks, Brian M; Nigg, Joel T; Zucker, Robert A; Hyde, Luke W	October 1, 2017	Not Determined
28782975	Create Study	Heterogeneity in development of aspects of working memory predicts longitudinal attention deficit hyperactivity disorder symptom change.	Journal of abnormal psychology	Karalunas, Sarah L; Gustafsson, Hanna C; Dieckmann, Nathan F; Tipsord, Jessica; Mitchell, Suzanne H; Nigg, Joel T	August 1, 2017	Not Determined
28742874	Create Study	The relationship between early and late event-related potentials and temperament in adolescents with and without ADHD.	PloS one	Alperin, Brittany R; Gustafsson, Hanna; Smith, Christiana; Karalunas, Sarah L	January 1, 2017	Not Determined
28103058	Create Study	Emotion Dysregulation Across Emotion Systems in Attention Deficit/Hyperactivity Disorder.	Journal of clinical child and adolescent psychology : the official journal for the Society of Clinical Child and Adolescent Psychology, American Psychological Association, Division 53	Musser, Erica D; Nigg, Joel T	January 1, 2019	Not Determined
28094999	Create Study	Specificity of executive functioning and processing speed problems in common psychopathology.	Neuropsychology	Nigg, Joel T; Jester, Jennifer M; Stavro, Gillian M; Ip, Ka I; Puttler, Leon I; Zucker, Robert A	May 1, 2017	Not Determined
28083448	Create Study	A network analysis of developmental change in ADHD symptom structure from preschool to adulthood.	Clinical psychological science : a journal of the Association for Psychological Science	Martel, Michelle M; Levinson, Cheri A; Langer, Julia K; Nigg, Joel T	November 1, 2016	Not Determined
28035675	Create Study	Annual Research Review: On the relations among self-regulation, self-control, executive functioning, effortful control, cognitive control, impulsivity, risk-taking, and inhibition for developmental psychopathology.	Journal of child psychology and psychiatry, and allied disciplines	Nigg, Joel T	April 1, 2017	Not Determined
27901266	Create Study	Maternal prepregnancy body mass index and offspring attention-deficit/hyperactivity disorder: a quasi-experimental sibling-comparison, population-based design.	Journal of child psychology and psychiatry, and allied disciplines	Musser, Erica D; Willoughby, Michael T; Wright, Suzanne; Sullivan, Elinor L; Stadler, Diane D; Olson, Brent F; Steiner, Robert D; Nigg, Joel T	March 1, 2017	Not Determined
27868421	Create Study	Sex moderates the impact of birth weight on child externalizing psychopathology.	Journal of abnormal psychology	Momany, Allison M; Kamradt, Jaclyn M; Ullsperger, Josie M; Elmore, Alexis L; Nigg, Joel T; Nikolas, Molly A	February 1, 2017	Not Determined
27150661	Create Study	Executive function and intelligence in the resolution of temporary syntactic ambiguity: an individual differences investigation.	Quarterly journal of experimental psychology (2006)	Engelhardt, Paul E; Nigg, Joel T; Ferreira, Fernanda	July 1, 2017	Not Determined
27126924	Create Study	Psychometrically Informed Approach to Integration of Multiple Informant Ratings in Adult ADHD in a Community-Recruited Sample.	Assessment	Martel, Michelle M; Nigg, Joel T; Schimmack, Ulrich	April 1, 2017	Not Determined
27125993	Create Study	The Association of Lifestyle Factors and ADHD in Children.	Journal of attention disorders	Holton, Kathleen F; Nigg, Joel T	September 1, 2020	Not Determined
27049476	Create Study	Neuropsychological performance measures as intermediate phenotypes for attention-deficit/hyperactivity disorder: A multiple mediation analysis.	Development and psychopathology	Kamradt, Jaclyn M; Nigg, Joel T; Friderici, Karen H; Nikolas, Molly A	February 1, 2017	Not Determined
26961824	Create Study	Pre- and Perinatal Risk for Attention-Deficit Hyperactivity Disorder: Does Neuropsychological Weakness Explain the Link?	Journal of abnormal child psychology	Wiggs, Kelsey; Elmore, Alexis L; Nigg, Joel T; Nikolas, Molly A	November 1, 2016	Not Determined
26889897	Create Study	Commentary: Risk taking, impulsivity, and externalizing problems in adolescent development--commentary on Crone et al. 2016.	Journal of child psychology and psychiatry, and allied disciplines	Nigg, Joel T; Nagel, Bonnie J	March 1, 2016	Not Determined
26854504	Create Study	Attention-deficit/hyperactivity disorder developmental trajectories related to parental expressed emotion.	Journal of abnormal psychology	Musser, Erica D; Karalunas, Sarah L; Dieckmann, Nathan; Peris, Tara S; Nigg, Joel T	February 1, 2016	Not Determined
26780581	Create Study	Attention-deficit/hyperactivity disorder (ADHD) and being overweight/obesity: New data and meta-analysis.	Clinical psychology review	Nigg, Joel T; Johnstone, Jeanette M; Musser, Erica D; Long, Hilary Galloway; Willoughby, Michael T; Shannon, Jackilen	February 1, 2016	Not Determined
26758288	Create Study	Where Do Epigenetics and Developmental Origins Take the Field of Developmental Psychopathology?	Journal of abnormal child psychology	Nigg, Joel T	April 1, 2016	Not Determined
26710823	Create Study	Variation in an Iron Metabolism Gene Moderates the Association Between Blood Lead Levels and Attention-Deficit/Hyperactivity Disorder in Children.	Psychological science	Nigg, Joel T; Elmore, Alexis L; Natarajan, Neil; Friderici, Karen H; Nikolas, Molly A	February 1, 2016	Not Determined
26408321	Create Study	Erratum to: Variation in Parasympathetic Dysregulation Moderates Short-term Memory Problems in Childhood Attention-Deficit/Hyperactivity Disorder.	Journal of abnormal child psychology	Ward, Anthony R; Alarcón, Gabriela; Nigg, Joel T; Musser, Erica D	November 1, 2015	Not Determined
26216249	Create Study	Variation in Parasympathetic Dysregulation Moderates Short-term Memory Problems in Childhood Attention-Deficit/Hyperactivity Disorder.	Journal of abnormal child psychology	Ward, Anthony R; Alarcón, Gabriela; Nigg, Joel T; Musser, Erica D	November 1, 2015	Not Determined
25796454	Create Study	Comparing hyperbolic, delay-amount sensitivity and present-bias models of delay discounting.	Behavioural processes	Mitchell, Suzanne H; Wilson, Vanessa B; Karalunas, Sarah L	May 1, 2015	Not Determined
25773396	Create Study	Editorial: The shape of the nosology to come in developmental psychopathology.	Journal of child psychology and psychiatry, and allied disciplines	Nigg, Joel T	April 1, 2015	Not Determined
25749651	Create Study	Recalled Initiation and Duration of Maternal Breastfeeding Among Children with and Without ADHD in a Well Characterized Case-Control Sample.	Journal of abnormal child psychology	Stadler, Diane D; Musser, Erica D; Holton, Kathleen F; Shannon, Jackilen; Nigg, Joel T	February 1, 2016	Not Determined
25730162	Create Study	Integration of symptom ratings from multiple informants in ADHD diagnosis: a psychometric model with clinical utility.	Psychological assessment	Martel, Michelle M; Schimmack, Ulrich; Nikolas, Molly; Nigg, Joel T	September 1, 2015	Not Determined
25684446	Create Study	Does Child Temperament Play a Role in the Association Between Parenting Practices and Child Attention Deficit/Hyperactivity Disorder?	Journal of abnormal child psychology	Ullsperger, Josie M; Nigg, Joel T; Nikolas, Molly A	January 1, 2016	Not Determined
25602736	Create Study	Does 5HTTLPR Genotype Moderate the Association of Family Environment With Child Attention-Deficit Hyperactivity Disorder Symptomatology?	Journal of clinical child and adolescent psychology : the official journal for the Society of Clinical Child and Adolescent Psychology, American Psychological Association, Division 53	Elmore, Alexis L; Nigg, Joel T; Friderici, Karen H; Jernigan, Katherine; Nikolas, Molly A	January 1, 2016	Not Determined
25181335	Create Study	Omega-3 fatty acid and ADHD: blood level analysis and meta-analytic extension of supplementation trials.	Clinical psychology review	Hawkey, Elizabeth; Nigg, Joel T	August 1, 2014	Not Determined
25037459	Create Study	Moderators of neuropsychological mechanism in attention-deficit hyperactivity disorder.	Journal of abnormal child psychology	Nikolas, Molly A; Nigg, Joel T	February 1, 2015	Not Determined
25006969	Create Study	Subtyping attention-deficit/hyperactivity disorder using temperament dimensions: toward biologically based nosologic criteria.	JAMA psychiatry	Karalunas, Sarah L; Fair, Damien; Musser, Erica D; Aykes, Kamari; Iyer, Swathi P; Nigg, Joel T	September 1, 2014	Not Determined
24708476	Create Study	Commentary: ADHD and social disadvantage: an inconvenient truth? --a reflection on Russell et al. () and Larsson et al. ().	Journal of child psychology and psychiatry, and allied disciplines	Nigg, Joel T; Craver, Lindsay	May 1, 2014	Not Determined
24628425	Create Study	Annual research review: Reaction time variability in ADHD and autism spectrum disorders: measurement and mechanisms of a proposed trans-diagnostic phenotype.	Journal of child psychology and psychiatry, and allied disciplines	Karalunas, Sarah L; Geurts, Hilde M; Konrad, Kerstin; Bender, Stephan; Nigg, Joel T	June 1, 2014	Not Determined
24480998	Create Study	Emotion dysregulation in attention deficit hyperactivity disorder.	The American journal of psychiatry	Shaw, Philip; Stringaris, Argyris; Nigg, Joel; Leibenluft, Ellen	March 1, 2014	Not Determined
24444366	Create Study	Shared familial transmission of autism spectrum and attention-deficit/hyperactivity disorders.	Journal of child psychology and psychiatry, and allied disciplines	Musser, Erica D; Hawkey, Elizabeth; Kachan-Liu, Svetlana S; Lees, Paul; Roullet, Jean-Baptiste; Goddard, Katrina; Steiner, Robert D; Nigg, Joel T	July 1, 2014	Not Determined
24214969	Create Study	Are There Executive Dysfunction Subtypes Within ADHD?	Journal of attention disorders	Roberts, Bethan A; Martel, Michelle M; Nigg, Joel T	February 1, 2017	Not Determined

helpcenter.collection.publications-tab

Collection - Publications

The number of Publications is displayed in parentheses next to the tab name. Clicking on any of the Publication Titles will open the Publication in a new internet browsing tab.

Collection Owners, Program Officers, and users with Submission or Administrative Privileges for the Collection may mark a publication as either Relevant or Not Relevant in the Status column.

Frequently Asked Questions

How can I determine if a publication is relevant?

Publications are considered relevant to a collection when the data shared is directly related to the project or collection.
Where does the NDA get the publications?

PubMed, an online library containing journals, articles, and medical research. Sponsored by NiH and National Library of Medicine (NLM).

Glossary

Create Study

A link to the Create an NDA Study page that can be clicked to start creating an NDA Study with information such as the title, journal and authors automatically populated.
Not Determined Publication

Indicates that the publication has not yet been reviewed and/or marked as Relevant or Not Relevant so it has not been determined whether an NDA Study is expected.
Not Relevant Publication

A publication that is not based on data related to the aims of the grant/project associated with the Collection or not based on any data such as a review article and, therefore, an NDA Study is not expected to be created.
PubMed

PubMed provides citation information for biomedical and life sciences publications and is managed by the U.S. National Institutes of Health's National Library of Medicine.
PubMed ID

The PUBMed ID is the unique ID number for the publication as recorded in the PubMed database.
Relevant Publication

A publication that is based on data related to the aims of the grant/project associated with the Collection and, therefore, an NDA Study is expected to be created.

Contact NDA Help Desk

Data Expected List: Mandatory Data Structures

These data structures are mandatory for your NDA Collection. Please update the Targeted Enrollment number to accurately represent the number of subjects you expect to submit for the entire study.

For NIMH HIV-related research that involves human research participants: Select the dictionary or dictionaries most appropriate for your research. If your research does not require all three data dictionaries, just ignore the ones you do not need. There is no need to delete extra data dictionaries from your NDA Collection. You can adjust the Targeted Enrollment column in the Data Expected tab to “0” for those unnecessary data dictionaries. At least one of the three data dictionaries must have a non-zero value.

Data Expected	Targeted Enrollment	Initial Submission	Subjects Submitted	Initial Share	Subjects Shared	Status
Research Subject and Pedigree	1,000	07/15/2021	2,525	12/31/2021	2,525	Approved

To create your project's Data Expected list, use the "+New Data Expected" to add or request existing structures and to request new Data Structures that are not in the NDA Data Dictionary.

If the Structure you need already exists, locate it and specify your dates and enrollment when adding it to your Data Expected list. If you require changes to the Structure you need, select the indicator stating "No, it requires changes to meet research needs," and upload a file containing your requested changes.

If the structure you need is not yet defined in the Data Dictionary, you can select "Upload Definition" and attach the necessary materials to request its creation.

When selecting the expected dates for your data, make sure to follow the standard Data Sharing Regimen and choose dates within the date ranges that correspond to your project start and end dates.

Please visit the Completing Your Data Expected Tutorial for more information.

Data Expected List: Data Structures per Research Aims

These data structures are specific to your research aims and should list all data structures in which data will be collected and submitted for this NDA Collection. Please update the Targeted Enrollment number to accurately represent the number of subjects you expect to submit for the entire study.

Data Expected	Targeted Enrollment	Initial Submission	Subjects Submitted	Initial Share	Subjects Shared	Status
Woodcock-Johnson Tests of Cognitive Abilities and Achievement	1,000	01/15/2022	1,147	05/15/2022	1,147	Approved
Delis-Kaplan Executive Function System (D-KEFS)	1,000	07/15/2022	496	11/15/2022	496	Approved
Medical History	1,000	07/15/2022	1,446	11/15/2022	0	Approved
Childrens Depression Inventory	1,000	07/15/2021	832	12/31/2021	832	Approved
Child Behavior Checklist (CBCL)	1,000	01/15/2022	926	05/15/2022	926	Approved
Behavior Assessment System for Children (BASC)	1,000	01/15/2022	364	05/15/2022	364	Approved
Wechsler Individual Achievement Test	1,000	07/15/2021	1,111	12/31/2021	1,111	Approved
Conners	1,000	07/15/2022	1,303	11/15/2022	1,303	Approved
Pubertal Development Scale (PDS)	496	12/31/2023	0	12/31/2024	0	Approved
Wechsler Intelligence Scale for Children	1,000	07/15/2021	1,110	12/31/2021	1,110	Approved
Wechsler Adult Intelligence Scale	1,000	01/15/2022	791	05/15/2022	791	Approved
Wide Range Achievement Test	1,000	07/15/2021	238	12/31/2021	238	Approved
Youth Self Report	1,000	07/15/2022	1,078	11/15/2022	1,078	Approved
ADHD Rating Scale	1,000	01/15/2022	1,328	05/15/2022	1,084	Approved
Color Reading Interference (Stroop)	1,000	01/15/2022	594	05/15/2022	594	Approved
Multidimensional Anxiety Scale for Children (MASC)	1,000	07/15/2021	954	12/31/2021	954	Approved
Alabama Parenting Questionnaire	1,000	01/15/2022	915	05/15/2022	915	Approved
Early Adolescent Temperament Questionnaire	1,000	01/15/2022	725	05/15/2022	725	Approved
Continuous Performance Test	1,000	07/15/2022	0	11/15/2022	0	Approved
Strengths and Weakness of ADHD Symptoms and Normal Behavior	1,000	07/15/2021	877	12/31/2021	877	Approved
O'Leary Porter Scale	1,000	07/15/2022	770	11/15/2022	770	Approved
Stop Signal Test	1,000	07/15/2022	478	11/15/2022	0	Approved
Children's Perception of Interparental Conflict Scale	1,000	07/15/2022	1,022	11/15/2022	1,022	Approved
Family Environment Scale	1,000	01/15/2022	493	05/15/2022	493	Approved
Conners-Wells Self-Report Scale	1,000	01/15/2022	361	05/15/2022	361	Approved
Common Language Q-Sort	1,000	07/15/2022	853	11/15/2022	853	Approved
Diagnostic Team Data	1,000	01/15/2023	1,443	05/15/2023	0	Approved
Trails Halstead-Reitan (trails_hr01)	496	12/31/2023	0	12/31/2024	0	Requested New

Structure not yet defined

No Status history for this Data Expected has been recorded yet

helpcenter.collection.data-expected-tab

Collection - Data Expected

The Data Expected tab displays the list of all data that NDA expects to receive in association with the Collection as defined by the contributing researcher, as well as the dates for the expected initial upload of the data, and when it is first expected to be shared, or with the research community. Above the primary table of Data Expected, any publications determined to be relevant to the data within the Collection are also displayed - members of the contributing research group can use these to define NDA Studies, connecting those papers to underlying data in NDA.

The tab is used both as a reference for those accessing shared data, providing information on what is expected and when it will be shared, and as the primary tracking mechanism for contributing projects. It is used by both contributing primary researchers, secondary researchers, and NIH Program and Grants Management staff.

Researchers who are starting their project need to update their Data Expected list to include all the Data Structures they are collecting under their grant and set their initial submission and sharing schedule according to the NDA Data Sharing Regimen.

To add existing Data Structures from the Data Dictionary, to request new Data Structure that are not in the Dictionary, or to request changes to existing Data Structures, click "+New Data Expected".

For step-by-step instructions on how to add existing Data Structures, request changes to an existing Structure, or request a new Data Structure, please visit the Completing Your Data Expected Tutorial.

If you are a contributing researcher creating this list for the first time, or making changes to the list as your project progress, please note the following:

Although items you add to the list and changes you make are displayed, they are not committed to the system until you Save the entire page using the "Save" button at the bottom of your screen. Please Save after every change to ensure none of your work is lost.
If you attempt to add a new structure, the title you provide must be unique - if another structure exists with the same name your change will fail.
Adding a new structure to this list is the only way to request the creation of a new Data Dictionary definition.

Frequently Asked Questions

What is an NDA Data Structure?

An NDA Data Structure is comprised of multiple Data Elements to make up an electronic definition of an assessment, measure, questionnaire, etc will have a corresponding Data Structure.
What is the NDA Data Dictionary?

The NDA Data Dictionary is comprised of electronic definitions known as Data Structures.

Glossary

Analyzed Data

Data specific to the primary aims of the research being conducted (e.g. outcome measures, other dependent variables, observations, laboratory results, analyzed images, volumetric data, etc.) including processed images.
Data Item

Items listed on the Data Expected list in the Collection which may be an individual and discrete Data Structure, Data Structure Category, or Data Structure Group.
Data Structure

A defined organization and group of Data Elements to represent an electronic definition of a measure, assessment, questionnaire, or collection of data points. Data structures that have been defined in the NDA Data Dictionary are available at https://nda.nih.gov/general-query.html?q=query=data-structure
Data Structure Category

An NDA term describing the affiliation of a Data Structure to a Category, which may be disease/disorder or diagnosis related (Depression, ADHD, Psychosis), specific to data type (MRI, eye tracking, omics), or type of data (physical exam, IQ).
Data Structure Group

A Data Item listed on the Data Expected tab of a Collection that indicates a group of Data Structures (e.g., ADOS or SCID) for which data may be submitted instead of a specific Data Structure identified by version, module, edition, etc. For example, the ADOS Data Structure Category includes every ADOS Data Structure such as ADOS Module 1, ADOS Module 2, ADOS Module 1 - 2nd Edition, etc. The SCID Data Structure Group includes every SCID Data Structure such as SCID Mania, SCID V Mania, SCID PTSD, SCID-V Diagnosis, and more.
Evaluated Data

A new Data Structure category, Evaluated Data is analyzed data resulting from the use of computational pipelines in the Cloud and can be uploaded directly back to a miNDAR database. Evaluated Data is expected to be listed as a Data Item in the Collection's Data Expected Tab.
Imaging Data

Imaging+ is an NDA term which encompasses all imaging related data including, but not limited to, images (DTI, MRI, PET, Structural, Spectroscopy, etc.) as well as neurosignal data (EEG, fMRI, MEG, EGG, eye tracking, etc.) and Evaluated Data.
Initial Share Date

Initial Submission and Initial Share dates should be populated according to the NDA Data Sharing Terms and Conditions. Any modifications to these will go through the approval processes outlined above. Data will be shared with authorized users upon publication (via an NDA Study) or 1-2 years after the grant end date specified on the first Notice of Award, as defined in the applicable Data Sharing Terms and Conditions.
Initial Submission Date

Initial Submission and Initial Share dates should be populated according to these NDA Data Sharing Terms and Conditions. Any modifications to these will go through the approval processes outlined above. Data for all subjects is not expected on the Initial Submission Date and modifications may be made as necessary based on the project's conduct.
Research Subject and Pedigree

An NDA created Data Structure used to convey basic information about the subject such as demographics, pedigree (links family GUIDs), diagnosis/phenotype, and sample location that are critical to allow for easier querying of shared data.
Submission Cycle

The NDA has two Submission Cycles per year - January 15 and July 15.
Submission Exemption

An interface to notify NDA that data may not be submitted during the upcoming/current submission cycle.

Contact NDA Help Desk

Collection Owners and those with Collection Administrator permission, may edit a collection. The following is currently available for Edit on this page:

Associated Studies

Studies that have been defined using data from a Collection are important criteria to determine the value of data shared. The number of subjects column displays the counts from this Collection that are included in a Study, out of the total number of subjects in that study. The Data Use column represents whether or not the study is a primary analysis of the data or a secondary analysis. State indicates whether the study is private or shared with the research community.

Study NameFilter by Study Name	AbstractFilter by Abstract	Collection/Study SubjectsFilter by Collection/Study Subjects	Data UsageFilter by Data Usage	StateFilter by State
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helpcenter.collection.associated-studies-tab

Collection - Associated Studies

Clicking on the Study Title will open the study details in a new internet browser tab. The Abstract is available for viewing, providing the background explanation of the study, as provided by the Collection Owner.

Primary v. Secondary Analysis: The Data Usage column will have one of these two choices. An associated study that is listed as being used for Primary Analysis indicates at least some and potentially all of the data used was originally collected by the creator of the NDA Study. Secondary Analysis indicates the Study owner was not involved in the collection of data, and may be used as supporting data.

Private v. Shared State: Studies that remain private indicate the associated study is only available to users who are able to access the collection. A shared study is accessible to the general public.

Frequently Asked Questions

How do I associate a study to my collection?

Studies are associated to the Collection automatically when the data is defined in the Study.

Glossary

Associated Studies Tab

A tab in a Collection that lists the NDA Studies that have been created using data from that Collection including both Primary and Secondary Analysis NDA Studies.

Contact NDA Help Desk

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Frequently Asked Questions

Glossary