NIMH Data Archive - Data

Genomics

Neuroimaging

Phenotype¹

New Trial
Clinical Trial

¹ Numbers reported are subjects by age

New Project
Grant/Project Number

Format should be in the following format: Activity Code, Institute Abbreviation, and Serial Number. Grant Type, Support Year, and Suffix should be excluded. For example, grant 1R01MH123456-01A1 should be entered R01MH123456

Collection - Use Existing Experiment

To associate an experiment to the current collection, just select an axperiment from the table below then click the associate experiment button to persist your changes (saving the collection is not required). Note that once an experiment has been associated to two or more collections, the experiment will not longer be editable.

The table search feature is case insensitive and targets the experiment id, experiment name and experiment type columns. The experiment id is searched only when the search term entered is a number, and filtered using a startsWith comparison. When the search term is not numeric the experiment name is used to filter the results.

Select	Experiment Id	Experiment Name	Experiment Type	Created On

24	HI-NGS_R1	Omics	02/16/2011
475	MB1-10 (CHOP)	Omics	06/07/2016
490	Illumina Infinium PsychArray BeadChip Assay	Omics	07/07/2016
501	PharmacoBOLD Resting State	fMRI	07/27/2016
506	PVPREF	Omics	08/05/2016
509	ABC-CT Resting v2	EEG	08/18/2016
13	Comparison of FI expression in Autistic and Neurotypical Homo Sapiens	Omics	12/28/2010
18	AGRE/Broad Affymetrix 5.0 Genotype Experiment	Omics	01/06/2011
22	Stitching PCR Sequencing	Omics	02/14/2011
26	ASD_Methylation	Omics	03/01/2011
29	Microarray family 03 (father, mother, sibling)	Omics	03/24/2011
37	Standard paired-end sequencing of BCRs	Omics	04/19/2011
38	Illumina Mate-Pair BCR sequencing	Omics	04/19/2011
39	Custom Jumping Libraries	Omics	04/19/2011
40	Custom CapBP	Omics	04/19/2011
41	Immunofluorescence	Omics	05/11/2011
43	Autism brain sample genotyping, Illumina	Omics	05/16/2011
47	ARRA Autism Sequencing Collaboration at Baylor. SOLiD 4 System	Omics	08/01/2011
53	AGRE Omni1-quad	Omics	10/11/2011
59	AGP genotyping	Omics	04/03/2012
60	Ultradeep 454 sequencing of synaptic genes from postmortem cerebella of individuals with ASD and neurotypical controls	Omics	06/23/2012
63	Microemulsion PCR and Targeted Resequencing for Variant Detection in ASD	Omics	07/20/2012
76	Whole Genome Sequencing in Autism Families	Omics	01/03/2013
519	Resting	fMRI	11/08/2016
90	Genotyped IAN Samples	Omics	07/09/2013
91	NJLAGS Axiom Genotyping Array	Omics	07/16/2013
93	AGP genotyping (CNV)	Omics	09/06/2013
106	Longitudinal Sleep Study. H20 200. Channel set 2	EEG	11/07/2013
107	Longitudinal Sleep Study. H20 200. Channel set 3	EEG	11/07/2013
108	Longitudinal Sleep Study. AURA 200	EEG	11/07/2013
105	Longitudinal Sleep Study. H20 200. Channel set 1	EEG	11/07/2013
109	Longitudinal Sleep Study. AURA 400	EEG	11/07/2013
116	Gene Expression Analysis WG-6	Omics	01/07/2014
131	Jeste Lab UCLA ACEii: Charlie Brown and Sesame Street - Project 1	Eye Tracking	02/27/2014
132	Jeste Lab UCLA ACEii: Animacy - Project 1	Eye Tracking	02/27/2014
133	Jeste Lab UCLA ACEii: Mom Stranger - Project 2	Eye Tracking	02/27/2014
134	Jeste Lab UCLA ACEii: Face Emotion - Project 3	Eye Tracking	02/27/2014
145	AGRE/FMR1_Illumina.JHU	Omics	04/14/2014
146	AGRE/MECP2_Sanger.JHU	Omics	04/14/2014
147	AGRE/MECP2_Junior.JHU	Omics	04/14/2014
151	Candidate Gene Identification in familial Autism	Omics	06/09/2014
152	NJLAGS Whole Genome Sequencing	Omics	07/01/2014
154	Math Autism Study - Vinod Menon	fMRI	07/15/2014
155	Resting	fMRI	07/25/2014
156	Speech	fMRI	07/25/2014
159	Emotion	fMRI	07/25/2014
160	syllable contrast	EEG	07/29/2014
167	School-age naturalistic stimuli	Eye Tracking	09/19/2014
44	AGRE/Broad Affymetrix 5.0 Genotype Experiment	Omics	06/27/2011
45	Exome Sequencing of 20 Sporadic Cases of Autism Spectrum Disorder	Omics	07/15/2011

Collection - Add Experiment

Add Supporting Documentation

Funding Source:
URL:

To add an existing Data Structure, enter its title in the search bar. If you need to request changes, select the indicator "No, it requires changes to meet research needs" after selecting the Structure, and upload the file with the request changes specific to the selected Data Structure. Your file should follow the Request Changes Procedure. If the Data Structure does not exist, select "Request New Data Structure" and upload the appropriate zip file.

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Please confirm that you will not be enrolling any more subjects and that all raw data has been collected and submitted.

Collection Updated

Your Collection is now in Data Analysis phase and exempt from biannual submissions. Analyzed data is still expected prior to publication or no later than the project end date.

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Data Expected Item	Original Sharing Date	New Sharing Date

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Characterizing mechanistic heterogeneity across ADHD and Autism #1955

General
Experiments (1)
Shared Data
Publications (90)
Data Expected (17)
Associated Studies (3)

Collection Title	Collection Investigators	Collection Description
Collection Title:	Characterizing mechanistic heterogeneity across ADHD and Autism
Collection Investigators:	Damien Fair
Collection Description:	Progress in establishing the etiology of psychiatric illness is limited by the absence of objective biological measures able to detect and discriminate between disorders. This problem is particularly important in developmental disorders, where early identification could eventually assist in prevention of life long impairments. The two earliest onset, most common, and costly developmental disorders in child psychiatry are attention deficit hyperactivity disorder (ADHD) and Autism spectrum disorders (ASD). A recent 2011 study, surveying the years 1997-2008, has now verified that 1 in 6 children have a developmental disability, a 17% increase over the past decade driven largely by increases in ASD and ADHD. These developments highlight the need for innovative approaches to address the underlying cause of these disorders. It is likely that the clinical heterogeneity and the imprecise nature of their nosological distinctions represent fundamentally confounding factors limiting a better understanding of their etiology, prevention, and treatment. Interestingly, an emerging observation regarding brain imaging in ASD and ADHD is that they often have the same atypical functional brain signatures. However, because these two syndromes are almost exclusively studied separately, it is difficult to determine atypical brain function that is common, compared to what is distinct for each disorder. If we are to improve our understanding regarding the underlying etiology of these disorders, it will be necessary to study these populations simultaneously. With that said, simply comparing groups of children based on their DSM diagnosis is unlikely to suffice. The behavioral and biological heterogeneity within each syndrome further complicates the meaning of any given group difference found in brain imaging. Thus, progress in our understanding requires not only examining these disorders in the same studies, but also identifying how brain signatures relate to distinct behavioral components (i.e., endophenotypes) that span the syndromes. Under this context, and consistent with NIMHs new strategic plan, Strategy 1.4 (also see RDoC), the current proposal aims to use resting state functional connectivity MRI (rsfcMRI) and structural connectivity (DTI) to identify brain signatures that correspond to fundamental behavioral components (executive, facial recognition, and affect recognition) found in ADHD and, or ASD. We also aim to develop integrated, multimodal sub-classifications (i.e. neurotypes) or biosignatures of these disorders with computational tools that include Graph Theory and support vector machine (SVM) based pattern classification. The potential impact of the proposed mechanistic categorization on future functional, genetic, treatment, and other translational studies of ADHD and ASD are substantial.
Data Repository:	NIMH Data Archive
Permission Group:
Collection Creation Date:	06/18/2012
Collection Phase:	Funding Completed
Collection Sub-Phase:	Close Out
Blinded Clinical Trial:	No
Total Funded Amount:	$1,870,295.00
Subjects Shared:	346

{"values":[]}

{"values":[["Not Defined",23]]}

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Funding Sources:

Funding Source Name	Funding Source URL
NIH - Extramural	None

Supporting Documentation:

File Name	File Type	Description	Audience
QA-notification.txt	Other	Quality Assurance Notification	Qualified Researchers

Grant Information:

Project Number	Project Title	Start Date	End Date	Planned Enrollment	Actual Enrollment	Organization	Funds Obligated
R01MH096773-01	Characterizing mechanistic heterogeneity across ADHD and Autism	08/06/2012	11/30/2018	323	316	OREGON HEALTH & SCIENCE UNIVERSITY	$1,870,295.00

Clinical Trials:

helpcenter.collection.general-tab

Collection - General Tab

Fields available for edit on the top portion of the page include:

Collection Title
Investigators
Collection Description
Collection Phase
Funding Source
Clinical Trials

Collection Phase: The current status of a research project submitting data to an NDA Collection, based on the timing of the award and/or the data that have been submitted.

Pre-Enrollment: The default entry made when the NDA Collection is created.
Enrolling: Data have been submitted to the NDA Collection or the NDA Data Expected initial submission date has been reached for at least one data structure category in the NDA Collection.
Data Analysis: Subject level data collection for the research project is completed and has been submitted to the NDA Collection. The NDA Collection owner or the NDA Help Desk may set this phase when they’ve confirmed data submission is complete and submitted subject counts match at least 90% of the target enrollment numbers in the NDA Data Expected. Data submission reminders will be turned off for the NDA Collection.
Funding Completed: The NIH grant award (or awards) associated with the NDA Collection has reached its end date. NDA Collections in Funding Completed phase are assigned a subphase to indicate the status of data submission.
- The Data Expected Subphase indicates that NDA expects more data will be submitted
- The Closeout Subphase indicates the data submission is complete.
- The Sharing Not Met Subphase indicates that data submission was not completed as expected.

Blinded Clinical Trial Status:

This status is set by a Collection Owner and indicates the research project is a double blinded clinical trial. When selected, the public view of Data Expected will show the Data Expected items and the Submission Dates, but the targeted enrollment and subjects submitted counts will not be displayed.
Targeted enrollment and subjects submitted counts are visible only to NDA Administrators and to the NDA Collection or as the NDA Collection Owner.
When an NDA Collection that is flagged Blinded Clinical Trial reaches the maximum data sharing date for that Data Repository (see https://nda.nih.gov/nda/sharing-regimen.html), the embargo on Data Expected information is released.

Funding Source

The organization(s) responsible for providing the funding is listed here.

Supporting Documentation

Users with Submission privileges, as well as Collection Owners, Program Officers, and those with Administrator privileges, may upload and attach supporting documentation. By default, supporting documentation is shared to the general public, however, the option is also available to limit this information to qualified researchers only.

Grant Information

Identifiable details are displayed about the Project of which the Collection was derived from. You may click in the Project Number to view a full report of the Project captured by the NIH.

Clinical Trials

Any data that is collected to support or further the research of clinical studies will be available here. Collection Owners and those with Administrator privileges may add new clinical trials.

Frequently Asked Questions

How does the NIMH Data Archive (NDA) determine which Permission Group data are submitted into?

During Collection creation, NDA staff determine the appropriate Permission Group based on the type of data to be submitted, the type of access that will be available to data access users, and the information provided by the Program Officer during grant award.
How do I know when a NDA Collection has been created?

When a Collection is created by NDA staff, an email notification will automatically be sent to the PI(s) of the grant(s) associated with the Collection to notify them.
Is a single grant number ever associated with more than one Collection?

The NDA system does not allow for a single grant to be associated with more than one Collection; therefore, a single grant will not be listed in the Grant Information section of a Collection for more than one Collection.
Why is there sometimes more than one grant included in a Collection?

In general, each Collection is associated with only one grant; however, multiple grants may be associated if the grant has multiple competing segments for the same grant number or if multiple different grants are all working on the same project and it makes sense to hold the data in one Collection (e.g., Cooperative Agreements).

Glossary

Administrator Privilege

A privilege provided to a user associated with an NDA Collection or NDA Study whereby that user can perform a full range of actions including providing privileges to other users.
Collection Owner

Generally, the Collection Owner is the contact PI listed on a grant. Only one NDA user is listed as the Collection owner. Most automated emails are primarily sent to the Collection Owner.
Collection Phase
The Collection Phase provides information on data submission as opposed to grant/project completion so while the Collection phase and grant/project phase may be closely related they are often different. Collection users with Administrative Privileges are encouraged to edit the Collection Phase. The Program Officer as listed in eRA (for NIH funded grants) may also edit this field. Changes must be saved by clicking the Save button at the bottom of the page. This field is sortable alphabetically in ascending or descending order. Collection Phase options include:
- Pre-Enrollment: A grant/project has started, but has not yet enrolled subjects.
- Enrolling: A grant/project has begun enrolling subjects. Data submission is likely ongoing at this point.
- Data Analysis: A grant/project has completed enrolling subjects and has completed all data submissions.
- Funding Completed: A grant/project has reached the project end date.
Collection Title

An editable field with the title of the Collection, which is often the title of the grant associated with the Collection.
Grant

Provides the grant number(s) for the grant(s) associated with the Collection. The field is a hyperlink so clicking on the Grant number will direct the user to the grant information in the NIH Research Portfolio Online Reporting Tools (RePORT) page.
Supporting Documentation

Various documents and materials to enable efficient use of the data by investigators unfamiliar with the project and may include the research protocol, questionnaires, and study manuals.
NIH Research Initiative

NDA Collections may be organized by scientific similarity into NIH Research Initiatives, to facilitate query tool user experience. NIH Research Initiatives map to one or multiple Funding Opportunity Announcements.
Permission Group

Access to shared record-level data in NDA is provisioned at the level of a Permission Group. NDA Permission Groups consist of one or multiple NDA Collections that contain data with the same subject consents.
Planned Enrollment

Number of human subject participants to be enrolled in an NIH-funded clinical research study. The data is provided in competing applications and annual progress reports.
Actual Enrollment

Number of human subjects enrolled in an NIH-funded clinical research study. The data is provided in annual progress reports.
NDA Collection

A virtual container and organization structure for data and associated documentation from one grant or one large project/consortium. It contains tools for tracking data submission and allows investigators to define a wide array of other elements that provide context for the data, including all general information regarding the data and source project, experimental parameters used to collect any event-based data contained in the Collection, methods, and other supporting documentation. They also allow investigators to link underlying data to an NDA Study, defining populations and subpopulations specific to research aims.
Data Use Limitations

Data Use Limitations (DULs) describe the appropriate secondary use of a dataset and are based on the original informed consent of a research participant. NDA only accepts consent-based data use limitations defined by the NIH Office of Science Policy.
Total Subjects Shared

The total number of unique subjects for whom data have been shared and are available for users with permission to access data.

Contact NDA Help Desk

ID	Name	Created Date	Status	Type
1532	Resting State fMRI	02/24/2020	Approved	fMRI

helpcenter.collection.experiments-tab

Collection - Experiments

The number of Experiments included is displayed in parentheses next to the tab name. You may download all experiments associated with the Collection via the Download button. You may view individual experiments by clicking the Experiment Name and add them to the Filter Cart via the Add to Cart button.

Collection Owners, Program Officers, and users with Submission or Administrative Privileges for the Collection may create or edit an Experiment.

Please note: The creation of an NDA Experiment does not necessarily mean that data collected, according to the defined Experiment, has been submitted or shared.

Frequently Asked Questions

Can an Experiment be associated with more than one Collection?
Yes -see the “Copy” button in the bottom left when viewing an experiment. There are two actions that can be performed via this button:
1. Copy the experiment with intent for modifications.
2. Associate the experiment to the collection. No modifications can be made to the experiment.

Glossary

Experiment Status

An Experiment must be Approved before data using the associated Experiment_ID may be uploaded.
Experiment ID

The ID number automatically generated by NDA which must be included in the appropriate file when uploading data to link the Experiment Definition to the subject record.

Contact NDA Help Desk

Shared Data:

Title	Type	Number of Subjects
ADHD Rating Scale	Clinical Assessments	291
Autism Diagnostic Interview, Revised (ADI-R)	Clinical Assessments	137
Autism Diagnostic Observation Schedule, 2nd Edition (ADOS-2) - Module 3	Clinical Assessments	106
BASC Parent Rating Scale Adolescent	Clinical Assessments	84
BASC Parent Rating Scale Child	Clinical Assessments	130
Child Depression Inventory (CDI)	Clinical Assessments	84
Children's Communication Checklist - 2	Clinical Assessments	339
Conners 3	Clinical Assessments	282
Demographics Short Form	Clinical Assessments	290
Image	Imaging	94
Imaging Collection	Imaging	92
Kiddie-Sads Current Diagnoses	Clinical Assessments	102
Multidimensional Anxiety Scale for Children Parent and Self	Clinical Assessments	80
Processed MRI Data	Imaging	90
Research Subject	Clinical Assessments	315
Social Communication Questionnaire (SCQ) - Current Form	Clinical Assessments	200
Strengths and Difficulties Questionnaire	Clinical Assessments	307

helpcenter.collection.shared-data-tab

Collection - Shared Data

This tab provides a quick overview of the Data Structure title, Data Type, and Number of Subjects that are currently Shared for the Collection. The information presented in this tab is automatically generated by NDA and cannot be edited. If no information is visible on this tab, this would indicate the Collection does not have shared data or the data is private.

The shared data is available to other researchers who have permission to access data in the Collection's designated Permission Group(s). Use the Download button to get all shared data from the Collection to the Filter Cart.

Frequently Asked Questions

How will I know if another researcher uses data that I shared through the NIMH Data Archive (NDA)?

To see what data your project have submitted are being used by a study, simply go the Associated Studies tab of your collection. Alternatively, you may review an NDA Study Attribution Report available on the General tab.
Can I get a supplement to share data from a completed research project?

Often it becomes more difficult to organize and format data electronically after the project has been completed and the information needed to create a GUID may not be available; however, you may still contact a program staff member at the appropriate funding institution for more information.
Can I get a supplement to share data from a research project that is still ongoing?

Unlike completed projects where researchers may not have the information needed to create a GUID and/or where the effort needed to organize and format data becomes prohibitive, ongoing projects have more of an opportunity to overcome these challenges. Please contact a program staff member at the appropriate funding institution for more information.

Glossary

Data Structure

A defined organization and group of Data Elements to represent an electronic definition of a measure, assessment, questionnaire, or collection of data points. Data structures that have been defined in the NDA Data Dictionary are available at https://nda.nih.gov/general-query.html?q=query=data-structure
Data Type

A grouping of data by similar characteristics such as Clinical Assessments, Omics, or Neurosignal data.
Shared

The term 'Shared' generally means available to others; however, there are some slightly different meanings based on what is Shared. A Shared NDA Study is viewable and searchable publicly regardless of the user's role or whether the user has an NDA account. A Shared NDA Study does not necessarily mean that data used in the NDA Study have been shared as this is independently determined. Data are shared according the schedule defined in a Collection's Data Expected Tab and/or in accordance with data sharing expectations in the NDA Data Sharing Terms and Conditions. Additionally, Supporting Documentation uploaded to a Collection may be shared independent of whether data are shared.

Contact NDA Help Desk

Collection Owners and those with Collection Administrator permission, may edit a collection. The following is currently available for Edit on this page:

Publications

Publications relevant to NDA data are listed below. Most displayed publications have been associated with the grant within Pubmed. Use the "+ New Publication" button to add new publications. Publications relevant/not relevant to data expected are categorized. Relevant publications are then linked to the underlying data by selecting the Create Study link. Study provides the ability to define cohorts, assign subjects, define outcome measures and lists the study type, data analysis and results. Analyzed data and results are expected in this way.

PubMed ID	Study	Title	Journal	Authors	Date	Status
39464007	Create Study	Baby Open Brains: An Open-Source Repository of Infant Brain Segmentations.	bioRxiv : the preprint server for biology	Feczko, Eric; Stoyell, Sally M; Moore, Lucille A; Alexopoulos, Dimitrios; Bagonis, Maria; Barrett, Kenneth; Bower, Brad; Cavender, Addison; Chamberlain, Taylor A; Conan, Greg; Day, Trevor Km; Goradia, Dhruman; Graham, Alice; Heisler-Roman, Lucas; Hendrickson, Timothy J; Houghton, Audrey; Kardan, Omid; Kiffmeyer, Elizabeth A; Lee, Erik G; Lundquist, Jacob T; Lucena, Carina; Martin, Tabitha; Mummaneni, Anurima; Myricks, Mollie; Narnur, Pranav; Perrone, Anders J; Reiners, Paul; Rueter, Amanda R; Saw, Hteemoo; Styner, Martin; Sung, Sooyeon; Tiklasky, Barry; Wisnowski, Jessica L; Yacoub, Essa; Zimmermann, Brett; Smyser, Christopher D; Rosenberg, Monica D; Fair, Damien A; Elison, Jed T	October 14, 2024	Not Determined
39020167	Create Study	Psilocybin desynchronizes the human brain.	Nature	Siegel, Joshua S; Subramanian, Subha; Perry, Demetrius; Kay, Benjamin P; Gordon, Evan M; Laumann, Timothy O; Reneau, T Rick; Metcalf, Nicholas V; Chacko, Ravi V; Gratton, Caterina; Horan, Christine; Krimmel, Samuel R; Shimony, Joshua S; Schweiger, Julie A; Wong, Dean F; Bender, David A; Scheidter, Kristen M; Whiting, Forrest I; Padawer-Curry, Jonah A; Shinohara, Russell T; Chen, Yong; Moser, Julia; Yacoub, Essa; Nelson, Steven M; Vizioli, Luca; Fair, Damien A; Lenze, Eric J; Carhart-Harris, Robin; Raison, Charles L; Raichle, Marcus E; Snyder, Abraham Z; Nicol, Ginger E; Dosenbach, Nico U F	August 1, 2024	Not Determined
38834704	Create Study	Cognitive control training with domain-general response inhibition does not change children''s brains or behavior.	Nature neuroscience	Ganesan, Keertana; Thompson, Abigail; Smid, Claire R; Cañigueral, Roser; Li, Yongjing; Revill, Grace; Puetz, Vanessa; Bernhardt, Boris C; Dosenbach, Nico U F; Kievit, Rogier; Steinbeis, Nikolaus	July 1, 2024	Not Determined
38607474	Create Study	Factors Associated with Confirmed and Unconfirmed Autism Spectrum Disorder Diagnosis in Children Volunteering for Research.	Journal of autism and developmental disorders	Duvall, Susanne W; Greene, Rachel K; Phelps, Randi; Rutter, Tara M; Markwardt, Sheila; Grieser Painter, Julia; Cordova, Michaela; Calame, Beth; Doyle, Olivia; Nigg, Joel T; Fombonne, Eric; Fair, Damien	April 12, 2024	Not Determined
38532024	Create Study	A precision functional atlas of personalized network topography and probabilities.	Nature neuroscience	Hermosillo, Robert J M; Moore, Lucille A; Feczko, Eric; Miranda-Domínguez, Óscar; Pines, Adam; Dworetsky, Ally; Conan, Gregory; Mooney, Michael A; Randolph, Anita; Graham, Alice; Adeyemo, Babatunde; Earl, Eric; Perrone, Anders; Carrasco, Cristian Morales; Uriarte-Lopez, Johnny; Snider, Kathy; Doyle, Olivia; Cordova, Michaela; Koirala, Sanju; Grimsrud, Gracie J; Byington, Nora; Nelson, Steven M; Gratton, Caterina; Petersen, Steven; Feldstein Ewing, Sarah W; Nagel, Bonnie J; Dosenbach, Nico U F; Satterthwaite, Theodore D; Fair, Damien A	May 1, 2024	Not Determined
38450221	Create Study	Proceedings of the 11th Annual Deep Brain Stimulation Think Tank: pushing the forefront of neuromodulation with functional network mapping, biomarkers for adaptive DBS, bioethical dilemmas, AI-guided neuromodulation, and translational advancements.	Frontiers in human neuroscience	Johnson, Kara A; Dosenbach, Nico U F; Gordon, Evan M; Welle, Cristin G; Wilkins, Kevin B; Bronte-Stewart, Helen M; Voon, Valerie; Morishita, Takashi; Sakai, Yuki; Merner, Amanda R; Lázaro-Muñoz, Gabriel; Williamson, Theresa; Horn, Andreas; Gilron, Ro'ee; O'Keeffe, Jonathan; Gittis, Aryn H; Neumann, Wolf-Julian; Little, Simon; Provenza, Nicole R; Sheth, Sameer A; Fasano, Alfonso; Holt-Becker, Abbey B; Raike, Robert S; Moore, Lisa; Pathak, Yagna J; Greene, David; Marceglia, Sara; Krinke, Lothar; Tan, Huiling; Bergman, Hagai; Pötter-Nerger, Monika; Sun, Bomin; Cabrera, Laura Y; McIntyre, Cameron C; Harel, Noam; Mayberg, Helen S; Krystal, Andrew D; Pouratian, Nader; Starr, Philip A; Foote, Kelly D; Okun, Michael S; Wong, Joshua K	January 1, 2024	Not Determined
38260662	Create Study	The brainstem''s red nucleus was evolutionarily upgraded to support goal-directed action.	bioRxiv : the preprint server for biology	Krimmel, Samuel R; Laumann, Timothy O; Chauvin, Roselyne J; Hershey, Tamara; Roland, Jarod L; Shimony, Joshua S; Willie, Jon T; Norris, Scott A; Marek, Scott; Van, Andrew N; Monk, Julia; Scheidter, Kristen M; Whiting, Forrest; Ramirez-Perez, Nadeshka; Metoki, Athanasia; Wang, Anxu; Kay, Benjamin P; Nahman-Averbuch, Hadas; Fair, Damien A; Lynch, Charles J; Raichle, Marcus E; Gordon, Evan M; Dosenbach, Nico U F	January 1, 2024	Not Determined
38077010	Create Study	Framewise multi-echo distortion correction for superior functional MRI.	bioRxiv : the preprint server for biology	Van, Andrew N; Montez, David F; Laumann, Timothy O; Suljic, Vahdeta; Madison, Thomas; Baden, Noah J; Ramirez-Perez, Nadeshka; Scheidter, Kristen M; Monk, Julia S; Whiting, Forrest I; Adeyemo, Babatunde; Chauvin, Roselyne J; Krimmel, Samuel R; Metoki, Athanasia; Rajesh, Aishwarya; Roland, Jarod L; Salo, Taylor; Wang, Anxu; Weldon, Kimberly B; Sotiras, Aristeidis; Shimony, Joshua S; Kay, Benjamin P; Nelson, Steven M; Tervo-Clemmens, Brenden; Marek, Scott A; Vizioli, Luca; Yacoub, Essa; Satterthwaite, Theodore D; Gordon, Evan M; Fair, Damien A; Tisdall, M Dylan; Dosenbach, Nico U F	November 29, 2023	Not Determined
38045258	Create Study	XCP-D: A Robust Pipeline for the post-processing of fMRI data.	bioRxiv : the preprint server for biology	Mehta, Kahini; Salo, Taylor; Madison, Thomas; Adebimpe, Azeez; Bassett, Danielle S; Bertolero, Max; Cieslak, Matthew; Covitz, Sydney; Houghton, Audrey; Keller, Arielle S; Luo, Audrey; Miranda-Dominguez, Oscar; Nelson, Steve M; Shafiei, Golia; Shanmugan, Sheila; Shinohara, Russell T; Sydnor, Valerie J; Feczko, Eric; Fair, Damien A; Satterthwaite, Theodore D	November 21, 2023	Not Determined
37987000	Create Study	Disuse-driven plasticity in the human thalamus and putamen.	bioRxiv : the preprint server for biology	Chauvin, Roselyne J; Newbold, Dillan J; Nielsen, Ashley N; Miller, Ryland L; Krimmel, Samuel R; Metoki, Athanasia; Wang, Anxu; Van, Andrew N; Montez, David F; Marek, Scott; Suljic, Vahdeta; Baden, Noah J; Ramirez-Perez, Nadeshka; Scheidter, Kristen M; Monk, Julia S; Whiting, Forrest I; Adeyemo, Babatunde; Snyder, Abraham Z; Kay, Benjamin P; Raichle, Marcus E; Laumann, Timothy O; Gordon, Evan M; Dosenbach, Nico U F	January 25, 2024	Not Determined
37972450	Create Study	Motor networks, but also non-motor networks predict motor signs in Parkinson''s disease.	NeuroImage. Clinical	Ragothaman, Anjanibhargavi; Mancini, Martina; Nutt, John G; Wang, Junping; Fair, Damien A; Horak, Fay B; Miranda-Dominguez, Oscar	January 1, 2023	Not Determined
37873065	Create Study	Substructure of the brain''s Cingulo-Opercular network.	bioRxiv : the preprint server for biology	D'Andrea, Carolina Badke; Laumann, Timothy O; Newbold, Dillan J; Nelson, Steven M; Nielsen, Ashley N; Chauvin, Roselyne; Marek, Scott; Greene, Deanna J; Dosenbach, Nico U F; Gordon, Evan M	October 10, 2023	Not Determined
37670606	Create Study	Maternal Perinatal Stress Trajectories and Negative Affect and Amygdala Development in Offspring.	The American journal of psychiatry	Marr, Mollie C; Graham, Alice M; Feczko, Eric; Nolvi, Saara; Thomas, Elina; Sturgeon, Darrick; Schifsky, Emma; Rasmussen, Jerod M; Gilmore, John H; Styner, Martin; Entringer, Sonja; Wadhwa, Pathik D; Korja, Riikka; Karlsson, Hasse; Karlsson, Linnea; Buss, Claudia; Fair, Damien A	October 1, 2023	Not Determined
37293735	Create Study	Thalamo-cortical and cerebello-cortical functional connectivity in development.	Cerebral cortex (New York, N.Y. : 1991)	Badke D'Andrea, Carolina; Marek, Scott; Van, Andrew N; Miller, Ryland L; Earl, Eric A; Stewart, Stephanie B; Dosenbach, Nico U F; Schlaggar, Bradley L; Laumann, Timothy O; Fair, Damien A; Gordon, Evan M; Greene, Deanna J	July 24, 2023	Not Determined
37285163	Create Study	Precision Neuroimaging for Localization-Related Psychiatry.	JAMA psychiatry	Laumann, Timothy O; Zorumski, Charles F; Dosenbach, Nico U F	August 1, 2023	Not Determined
37076628	Create Study	A somato-cognitive action network alternates with effector regions in motor cortex.	Nature	Gordon, Evan M; Chauvin, Roselyne J; Van, Andrew N; Rajesh, Aishwarya; Nielsen, Ashley; Newbold, Dillan J; Lynch, Charles J; Seider, Nicole A; Krimmel, Samuel R; Scheidter, Kristen M; Monk, Julia; Miller, Ryland L; Metoki, Athanasia; Montez, David F; Zheng, Annie; Elbau, Immanuel; Madison, Thomas; Nishino, Tomoyuki; Myers, Michael J; Kaplan, Sydney; Badke D'Andrea, Carolina; Demeter, Damion V; Feigelis, Matthew; Ramirez, Julian S B; Xu, Ting; Barch, Deanna M; Smyser, Christopher D; Rogers, Cynthia E; Zimmermann, Jan; Botteron, Kelly N; Pruett, John R; Willie, Jon T; Brunner, Peter; Shimony, Joshua S; Kay, Benjamin P; Marek, Scott; Norris, Scott A; Gratton, Caterina; Sylvester, Chad M; Power, Jonathan D; Liston, Conor; Greene, Deanna J; Roland, Jarod L; Petersen, Steven E; Raichle, Marcus E; Laumann, Timothy O; Fair, Damien A; Dosenbach, Nico U F	May 1, 2023	Not Determined
36890374	Create Study	Reply to: Multivariate BWAS can be replicable with moderate sample sizes.	Nature	Tervo-Clemmens, Brenden; Marek, Scott; Chauvin, Roselyne J; Van, Andrew N; Kay, Benjamin P; Laumann, Timothy O; Thompson, Wesley K; Nichols, Thomas E; Yeo, B T Thomas; Barch, Deanna M; Luna, Beatriz; Fair, Damien A; Dosenbach, Nico U F	March 1, 2023	Not Determined
36848718	Create Study	The Oregon ADHD-1000: A new longitudinal data resource enriched for clinical cases and multiple levels of analysis.	Developmental cognitive neuroscience	Nigg, Joel T; Karalunas, Sarah L; Mooney, Michael A; Wilmot, Beth; Nikolas, Molly A; Martel, Michelle M; Tipsord, Jessica; Nousen, Elizabeth K; Schmitt, Colleen; Ryabinin, Peter; Musser, Erica D; Nagel, Bonnie J; Fair, Damien A	April 1, 2023	Not Determined
36841702	Create Study	Current Approaches in Computational Psychiatry for the Data-Driven Identification of Brain-Based Subtypes.	Biological psychiatry	Brucar, Leyla R; Feczko, Eric; Fair, Damien A; Zilverstand, Anna	April 15, 2023	Not Determined
35970984	Create Study	Precision dynamical mapping using topological data analysis reveals a hub-like transition state at rest.	Nature communications	Saggar, Manish; Shine, James M; Liégeois, Raphaël; Dosenbach, Nico U F; Fair, Damien	August 15, 2022	Not Determined
35927072	Create Study	Linking Individual Differences in Personalized Functional Network Topography to Psychopathology in Youth.	Biological psychiatry	Cui, Zaixu; Pines, Adam R; Larsen, Bart; Sydnor, Valerie J; Li, Hongming; Adebimpe, Azeez; Alexander-Bloch, Aaron F; Bassett, Dani S; Bertolero, Max; Calkins, Monica E; Davatzikos, Christos; Fair, Damien A; Gur, Ruben C; Gur, Raquel E; Moore, Tyler M; Shanmugan, Sheila; Shinohara, Russell T; Vogel, Jacob W; Xia, Cedric H; Fan, Yong; Satterthwaite, Theodore D	December 15, 2022	Not Determined
35339687	Create Study	Accuracy and reliability of diffusion imaging models.	NeuroImage	Seider, Nicole A; Adeyemo, Babatunde; Miller, Ryland; Newbold, Dillan J; Hampton, Jacqueline M; Scheidter, Kristen M; Rutlin, Jerrel; Laumann, Timothy O; Roland, Jarod L; Montez, David F; Van, Andrew N; Zheng, Annie; Marek, Scott; Kay, Benjamin P; Bretthorst, G Larry; Schlaggar, Bradley L; Greene, Deanna J; Wang, Yong; Petersen, Steven E; Barch, Deanna M; Gordon, Evan M; Snyder, Abraham Z; Shimony, Joshua S; Dosenbach, Nico U F	July 1, 2022	Not Determined
35296861	Create Study	Reproducible brain-wide association studies require thousands of individuals.	Nature	Marek, Scott; Tervo-Clemmens, Brenden; Calabro, Finnegan J; Montez, David F; Kay, Benjamin P; Hatoum, Alexander S; Donohue, Meghan Rose; Foran, William; Miller, Ryland L; Hendrickson, Timothy J; Malone, Stephen M; Kandala, Sridhar; Feczko, Eric; Miranda-Dominguez, Oscar; Graham, Alice M; Earl, Eric A; Perrone, Anders J; Cordova, Michaela; Doyle, Olivia; Moore, Lucille A; Conan, Gregory M; Uriarte, Johnny; Snider, Kathy; Lynch, Benjamin J; Wilgenbusch, James C; Pengo, Thomas; Tam, Angela; Chen, Jianzhong; Newbold, Dillan J; Zheng, Annie; Seider, Nicole A; Van, Andrew N; Metoki, Athanasia; Chauvin, Roselyne J; Laumann, Timothy O; Greene, Deanna J; Petersen, Steven E; Garavan, Hugh; Thompson, Wesley K; Nichols, Thomas E; Yeo, B T Thomas; Barch, Deanna M; Luna, Beatriz; Fair, Damien A; Dosenbach, Nico U F	March 1, 2022	Not Determined
35288282	Create Study	Synthesizing pseudo-T2w images to recapture missing data in neonatal neuroimaging with applications in rs-fMRI.	NeuroImage	Kaplan, Sydney; Perrone, Anders; Alexopoulos, Dimitrios; Kenley, Jeanette K; Barch, Deanna M; Buss, Claudia; Elison, Jed T; Graham, Alice M; Neil, Jeffrey J; O'Connor, Thomas G; Rasmussen, Jerod M; Rosenberg, Monica D; Rogers, Cynthia E; Sotiras, Aristeidis; Fair, Damien A; Smyser, Christopher D	June 1, 2022	Not Determined
34404728	Create Study	Parallel hippocampal-parietal circuits for self- and goal-oriented processing.	Proceedings of the National Academy of Sciences of the United States of America	Zheng, Annie; Montez, David F; Marek, Scott; Gilmore, Adrian W; Newbold, Dillan J; Laumann, Timothy O; Kay, Benjamin P; Seider, Nicole A; Van, Andrew N; Hampton, Jacqueline M; Alexopoulos, Dimitrios; Schlaggar, Bradley L; Sylvester, Chad M; Greene, Deanna J; Shimony, Joshua S; Nelson, Steven M; Wig, Gagan S; Gratton, Caterina; McDermott, Kathleen B; Raichle, Marcus E; Gordon, Evan M; Dosenbach, Nico U F	August 24, 2021	Not Determined
33882349	Create Study	Minimal specifications for non-human primate MRI: Challenges in standardizing and harmonizing data collection.	NeuroImage	Autio, Joonas A; Zhu, Qi; Li, Xiaolian; Glasser, Matthew F; Schwiedrzik, Caspar M; Fair, Damien A; Zimmermann, Jan; Yacoub, Essa; Menon, Ravi S; Van Essen, David C; Hayashi, Takuya; Russ, Brian; Vanduffel, Wim	August 1, 2021	Not Determined
33753484	Create Study	Cingulo-opercular control network and disused motor circuits joined in standby mode.	Proceedings of the National Academy of Sciences of the United States of America	Newbold, Dillan J; Gordon, Evan M; Laumann, Timothy O; Seider, Nicole A; Montez, David F; Gross, Sarah J; Zheng, Annie; Nielsen, Ashley N; Hoyt, Catherine R; Hampton, Jacqueline M; Ortega, Mario; Adeyemo, Babatunde; Miller, Derek B; Van, Andrew N; Marek, Scott; Schlaggar, Bradley L; Carter, Alexandre R; Kay, Benjamin P; Greene, Deanna J; Raichle, Marcus E; Petersen, Steven E; Snyder, Abraham Z; Dosenbach, Nico U F	March 30, 2021	Not Determined
33663814	Create Study	Understanding Vulnerability and Adaptation in Early Brain Development using Network Neuroscience.	Trends in neurosciences	Graham, Alice M; Marr, Mollie; Buss, Claudia; Sullivan, Elinor L; Fair, Damien A	April 1, 2021	Not Determined
32758445	Create Study	Precision Neuroimaging Opens a New Chapter of Neuroplasticity Experimentation.	Neuron	Fair, Damien A; Yeo, B T Thomas	August 5, 2020	Not Determined
32553194	Create Study	Parsing Psychiatric Heterogeneity Through Common and Unique Circuit-Level Deficits.	Biological psychiatry	Satterthwaite, Theodore D; Feczko, Eric; Kaczkurkin, Antonia N; Fair, Damien A	July 1, 2020	Not Determined
32386742	Create Study	Methods and Challenges for Assessing Heterogeneity.	Biological psychiatry	Feczko, Eric; Fair, Damien A	July 1, 2020	Not Determined
32325210	Create Study	Removal of high frequency contamination from motion estimates in single-band fMRI saves data without biasing functional connectivity.	NeuroImage	Gratton, Caterina; Dworetsky, Ally; Coalson, Rebecca S; Adeyemo, Babatunde; Laumann, Timothy O; Wig, Gagan S; Kong, Tania S; Gratton, Gabriele; Fabiani, Monica; Barch, Deanna M; Tranel, Daniel; Miranda-Dominguez, Oscar; Fair, Damien A; Dosenbach, Nico U F; Snyder, Abraham Z; Perlmutter, Joel S; Petersen, Steven E; Campbell, Meghan C	August 2020	Not Determined
32305325	Create Study	Toward a Revised Nosology for Attention-Deficit/Hyperactivity Disorder Heterogeneity.	Biological psychiatry. Cognitive neuroscience and neuroimaging	Nigg, Joel T; Karalunas, Sarah L; Feczko, Eric; Fair, Damien A	August 2020	Not Determined
32217469	Create Study	Heterogeneity of executive function revealed by a functional random forest approach across ADHD and ASD.	NeuroImage. Clinical	Cordova, Michaela; Shada, Kiryl; Demeter, Damion V; Doyle, Olivia; Miranda-Dominguez, Oscar; Perrone, Anders; Schifsky, Emma; Graham, Alice; Fombonne, Eric; Langhorst, Beth; Nigg, Joel; Fair, Damien A; Feczko, Eric	January 1, 2020	Not Determined
32033925	Create Study	Polygenic Risk Score-Derived Subcortical Connectivity Mediates Attention-Deficit/Hyperactivity Disorder Diagnosis.	Biological psychiatry. Cognitive neuroscience and neuroimaging	Hermosillo, Robert J M; Mooney, Michael A; Fezcko, Eric; Earl, Eric; Marr, Mollie; Sturgeon, Darrick; Perrone, Anders; Dominguez, Oscar Miranda; Faraone, Stephen V; Wilmot, Beth; Nigg, Joel T; Fair, Damien A	March 2020	Not Determined
31973781	Create Study	Smaller total brain volume but not subcortical structure volume related to common genetic risk for ADHD.	Psychological medicine	Mooney, Michael A; Bhatt, Priya; Hermosillo, Robert J M; Ryabinin, Peter; Nikolas, Molly; Faraone, Stephen V; Fair, Damien A; Wilmot, Beth; Nigg, Joel T	June 2021	Not Determined
31778819	Create Study	Correction of respiratory artifacts in MRI head motion estimates.	NeuroImage	Fair, Damien A; Miranda-Dominguez, Oscar; Snyder, Abraham Z; Perrone, Anders; Earl, Eric A; Van, Andrew N; Koller, Jonathan M; Feczko, Eric; Tisdall, M Dylan; van der Kouwe, Andre; Klein, Rachel L; Mirro, Amy E; Hampton, Jacqueline M; Adeyemo, Babatunde; Laumann, Timothy O; Gratton, Caterina; Greene, Deanna J; Schlaggar, Bradley L; Hagler Jr, Donald J; Watts, Richard; Garavan, Hugh; Barch, Deanna M; Nigg, Joel T; Petersen, Steven E; Dale, Anders M; Feldstein-Ewing, Sarah W; Nagel, Bonnie J; Dosenbach, Nico U F	March 2020	Not Determined
31665252	Create Study	Maternal Interleukin-6 Is Associated With Macaque Offspring Amygdala Development and Behavior.	Cerebral cortex (New York, N.Y. : 1991)	Ramirez, Julian S B; Graham, Alice M; Thompson, Jacqueline R; Zhu, Jennifer Y; Sturgeon, Darrick; Bagley, Jennifer L; Thomas, Elina; Papadakis, Samantha; Bah, Muhammed; Perrone, Anders; Earl, Eric; Miranda-Dominguez, Oscar; Feczko, Eric; Fombonne, Eric J; Amaral, David G; Nigg, Joel T; Sullivan, Elinor L; Fair, Damien A	March 2020	Not Determined
31614255	Create Study	Identifying reproducible individual differences in childhood functional brain networks: An ABCD study.	Developmental cognitive neuroscience	Marek, Scott; Tervo-Clemmens, Brenden; Nielsen, Ashley N; Wheelock, Muriah D; Miller, Ryland L; Laumann, Timothy O; Earl, Eric; Foran, William W; Cordova, Michaela; Doyle, Olivia; Perrone, Anders; Miranda-Dominguez, Oscar; Feczko, Eric; Sturgeon, Darrick; Graham, Alice; Hermosillo, Robert; Snider, Kathy; Galassi, Anthony; Nagel, Bonnie J; Ewing, Sarah W Feldstein; Eggebrecht, Adam T; Garavan, Hugh; Dale, Anders M; Greene, Deanna J; Barch, Deanna M; Fair, Damien A; Luna, Beatriz; Dosenbach, Nico U F	December 2019	Not Determined
31153774	Create Study	The Heterogeneity Problem: Approaches to Identify Psychiatric Subtypes.	Trends in cognitive sciences	Feczko, Eric; Miranda-Dominguez, Oscar; Marr, Mollie; Graham, Alice M; Nigg, Joel T; Fair, Damien A	July 2019	Not Determined
31072758	Create Study	Interindividual Variability of Functional Connectivity in Awake and Anesthetized Rhesus Macaque Monkeys.	Biological psychiatry. Cognitive neuroscience and neuroimaging	Xu, Ting; Sturgeon, Darrick; Ramirez, Julian S B; Froudist-Walsh, Seán; Margulies, Daniel S; Schroeder, Charles E; Fair, Damien A; Milham, Michael P	June 2019	Not Determined
30583065	Create Study	Comparing directed functional connectivity between groups with confirmatory subgrouping GIMME.	NeuroImage	Henry, Teague Rhine; Feczko, Eric; Cordova, Michaela; Earl, Eric; Williams, Sandra; Nigg, Joel T; Fair, Damien A; Gates, Kathleen M	March 2019	Not Determined
30581123	Create Study	Newborn amygdala connectivity and early emerging fear.	Developmental cognitive neuroscience	Thomas, Elina; Buss, Claudia; Rasmussen, Jerod M; Entringer, Sonja; Ramirez, Julian S B; Marr, Mollie; Rudolph, Marc D; Gilmore, John H; Styner, Martin; Wadhwa, Pathik D; Fair, Damien A; Graham, Alice M	June 2019	Not Determined
30465762	Create Study	The Big Reveal: Precision Mapping Shines a Gigantic Floodlight on the Cerebellum.	Neuron	Fair DA	November 2018	Not Determined
30315209	Create Study	Community profiling of the urinary microbiota: considerations for low-biomass samples.	Nature reviews. Urology	Karstens, Lisa; Asquith, Mark; Caruso, Vincent; Rosenbaum, James T; Fair, Damien A; Braun, Jonathan; Gregory, W Thomas; Nardos, Rahel; McWeeney, Shannon K	December 2018	Not Determined
30215033	Create Study	ADHD and attentional control: Impaired segregation of task positive and task negative brain networks.	Network neuroscience (Cambridge, Mass.)	Mills, Brian D; Miranda-Dominguez, Oscar; Mills, Kathryn L; Earl, Eric; Cordova, Michaela; Painter, Julia; Karalunas, Sarah L; Nigg, Joel T; Fair, Damien A	January 1, 2018	Not Determined
30122286	Create Study	Maternal Cortisol Concentrations During Pregnancy and Sex-Specific Associations With Neonatal Amygdala Connectivity and Emerging Internalizing Behaviors.	Biological psychiatry	Graham, Alice M; Rasmussen, Jerod M; Entringer, Sonja; Ben Ward, Elizabeth; Rudolph, Marc D; Gilmore, John H; Styner, Martin; Wadhwa, Pathik D; Fair, Damien A; Buss, Claudia	January 2019	Not Determined
30121543	Create Study	Individual differences in functional brain connectivity predict temporal discounting preference in the transition to adolescence.	Developmental cognitive neuroscience	Anandakumar J, Mills KL, Earl EA, Irwin L, Miranda-Dominguez O, Demeter DV, Walton-Weston A, Karalunas S, Nigg J, Fair DA	November 2018	Not Determined
29789379	Create Study	Correlated Gene Expression and Anatomical Communication Support Synchronized Brain Activity in the Mouse Functional Connectome.	The Journal of neuroscience : the official journal of the Society for Neuroscience	Mills, Brian D; Grayson, David S; Shunmugavel, Anandakumar; Miranda-Dominguez, Oscar; Feczko, Eric; Earl, Eric; Neve, Kim A; Fair, Damien A	June 2018	Not Determined
29764998	Create Study	Mapping cortical brain asymmetry in 17,141 healthy individuals worldwide via the ENIGMA Consortium.	Proceedings of the National Academy of Sciences of the United States of America	Kong, Xiang-Zhen; Mathias, Samuel R; Guadalupe, Tulio; ENIGMA Laterality Working Group; Glahn, David C; Franke, Barbara; Crivello, Fabrice; Tzourio-Mazoyer, Nathalie; Fisher, Simon E; Thompson, Paul M; Francks, Clyde	May 2018	Not Determined
29703592	Create Study	Personalized Intrinsic Network Topography Mapping and Functional Connectivity Deficits in Autism Spectrum Disorder.	Biological psychiatry	Dickie, Erin W; Ameis, Stephanie H; Shahab, Saba; Calarco, Navona; Smith, Dawn E; Miranda, Dayton; Viviano, Joseph D; Voineskos, Aristotle N	August 2018	Not Determined
29642002	Create Study	Delineating the Macroscale Areal Organization of the Macaque Cortex In Vivo.	Cell reports	Xu, Ting; Falchier, Arnaud; Sullivan, Elinor L; Linn, Gary; Ramirez, Julian S B; Ross, Deborah; Feczko, Eric; Opitz, Alexander; Bagley, Jennifer; Sturgeon, Darrick; Earl, Eric; Miranda-Domínguez, Oscar; Perrone, Anders; Craddock, R Cameron; Schroeder, Charles E; Colcombe, Stan; Fair, Damien A; Milham, Michael P	April 2018	Not Determined
29632361	Create Study	Maternal IL-6 during pregnancy can be estimated from newborn brain connectivity and predicts future working memory in offspring.	Nature neuroscience	Rudolph, Marc D; Graham, Alice M; Feczko, Eric; Miranda-Dominguez, Oscar; Rasmussen, Jerod M; Nardos, Rahel; Entringer, Sonja; Wadhwa, Pathik D; Buss, Claudia; Fair, Damien A	May 2018	Not Determined
29450820	Create Study	Overlapping and Distinct Cognitive Impairments in Attention-Deficit/Hyperactivity and Autism Spectrum Disorder without Intellectual Disability.	Journal of abnormal child psychology	Karalunas, Sarah L; Hawkey, Elizabeth; Gustafsson, Hanna; Miller, Meghan; Langhorst, Marybeth; Cordova, Michaela; Fair, Damien; Nigg, Joel T	November 2018	Not Determined
29408498	Create Study	Dysfunctional Limbic Circuitry Underlying Freezing of Gait in Parkinson's Disease.	Neuroscience	Gilat M, Ehgoetz Martens KA, Miranda-Domínguez O, Arpan I, Shine JM, Mancini M, Fair DA, Lewis SJG, Horak FB	March 2018	Not Determined
29337280	Create Study	Behavioral interventions for reducing head motion during MRI scans in children.	NeuroImage	Greene, Deanna J; Koller, Jonathan M; Hampton, Jacqueline M; Wesevich, Victoria; Van, Andrew N; Nguyen, Annie L; Hoyt, Catherine R; McIntyre, Lindsey; Earl, Eric A; Klein, Rachel L; Shimony, Joshua S; Petersen, Steven E; Schlaggar, Bradley L; Fair, Damien A; Dosenbach, Nico U F	May 2018	Not Determined
29274502	Create Study	Subtyping cognitive profiles in Autism Spectrum Disorder using a Functional Random Forest algorithm.	NeuroImage	Feczko, E; Balba, N M; Miranda-Dominguez, O; Cordova, M; Karalunas, S L; Irwin, L; Demeter, D V; Hill, A P; Langhorst, B H; Grieser Painter, J; Van Santen, J; Fombonne, E J; Nigg, J T; Fair, D A	May 2018	Not Determined
28803940	Create Study	Real-time motion analytics during brain MRI improve data quality and reduce costs.	NeuroImage	Dosenbach NUF, Koller JM, Earl EA, Miranda-Dominguez O, Klein RL, Van AN, Snyder AZ, Nagel BJ, Nigg JT, Nguyen AL, Wesevich V, Greene DJ, Fair DA	November 2017	Not Determined
28754515	Create Study	Maternal Systemic Interleukin-6 During Pregnancy Is Associated With Newborn Amygdala Phenotypes and Subsequent Behavior at 2 Years of Age.	Biological psychiatry	Graham, Alice M; Rasmussen, Jerod M; Rudolph, Marc D; Heim, Christine M; Gilmore, John H; Styner, Martin; Potkin, Steven G; Entringer, Sonja; Wadhwa, Pathik D; Fair, Damien A; Buss, Claudia	January 2018	Relevant
28577433	Create Study	Reduced fronto-amygdalar connectivity in adolescence is associated with increased depression symptoms over time.	Psychiatry research. Neuroimaging	Scheuer, Hannah; Alarcón, Gabriela; Demeter, Damion V; Earl, Eric; Fair, Damien A; Nagel, Bonnie J	August 2017	Not Determined
28291247	Create Study	Enhancing studies of the connectome in autism using the autism brain imaging data exchange II.	Scientific data	Di Martino, Adriana; O'Connor, David; Chen, Bosi; Alaerts, Kaat; Anderson, Jeffrey S; Assaf, Michal; Balsters, Joshua H; Baxter, Leslie; Beggiato, Anita; Bernaerts, Sylvie; Blanken, Laura M E; Bookheimer, Susan Y; Braden, B Blair; Byrge, Lisa; Castellanos, F Xavier; Dapretto, Mirella; Delorme, Richard; Fair, Damien A; Fishman, Inna; Fitzgerald, Jacqueline; Gallagher, Louise; Keehn, R Joanne Jao; Kennedy, Daniel P; Lainhart, Janet E; Luna, Beatriz; Mostofsky, Stewart H; Müller, Ralph-Axel; Nebel, Mary Beth; Nigg, Joel T; O'Hearn, Kirsten; Solomon, Marjorie; Toro, Roberto; Vaidya, Chandan J; Wenderoth, Nicole; White, Tonya; Craddock, R Cameron; Lord, Catherine; Leventhal, Bennett; Milham, Michael P	March 2017	Not Relevant
28279917	Create Study	At risk of being risky: The relationship between "brain age" under emotional states and risk preference.	Developmental cognitive neuroscience	Rudolph, Marc D; Miranda-Domínguez, Oscar; Cohen, Alexandra O; Breiner, Kaitlyn; Steinberg, Laurence; Bonnie, Richard J; Scott, Elizabeth S; Taylor-Thompson, Kim; Chein, Jason; Fettich, Karla C; Richeson, Jennifer A; Dellarco, Danielle V; Galván, Adriana; Casey, B J; Fair, Damien A	April 2017	Not Determined
28161313	Create Study	Development of large-scale functional networks from birth to adulthood: A guide to the neuroimaging literature.	NeuroImage	Grayson, David S; Fair, Damien A	October 2017	Not Determined
27477019	Create Study	The Rhesus Monkey Connectome Predicts Disrupted Functional Networks Resulting from Pharmacogenetic Inactivation of the Amygdala.	Neuron	Grayson DS, Bliss-Moreau E, Machado CJ, Bennett J, Shen K, Grant KA, Fair DA, Amaral DG	July 2016	Not Relevant
27422412	Create Study	Network Structure among Brain Systems in Adult ADHD is Uniquely Modified by Stimulant Administration.	Cerebral cortex (New York, N.Y. : 1991)	Cary RP, Ray S, Grayson DS, Painter J, Carpenter S, Maron L, Sporns O, Stevens AA, Nigg JT, Fair DA	August 2017	Not Determined
27050322	Create Study	Prenatal domoic acid exposure disrupts mouse pro-social behavior and functional connectivity MRI.	Behavioural brain research	Mills, Brian D; Pearce, Hadley L; Khan, Omar; Jarrett, Ben R; Fair, Damien A; Lahvis, Garet P	July 2016	Not Relevant
26499255	Create Study	Implications of newborn amygdala connectivity for fear and cognitive development at 6-months-of-age.	Developmental cognitive neuroscience	Graham, Alice M; Buss, Claudia; Rasmussen, Jerod M; Rudolph, Marc D; Demeter, Damion V; Gilmore, John H; Styner, Martin; Entringer, Sonja; Wadhwa, Pathik D; Fair, Damien A	April 2016	Not Determined
25809052	Create Study	Early life stress is associated with default system integrity and emotionality during infancy.	Journal of child psychology and psychiatry, and allied disciplines	Graham AM, Pfeifer JH, Fisher PA, Carpenter S, Fair DA	November 2015	Not Determined
25714740	Create Study	Commentary: Developmental connectomics to advance our understanding of typical and atypical brain development--a commentary on Vértes and Bullmore (2015).	Journal of child psychology and psychiatry, and allied disciplines	Graham, Alice M; Fair, Damien A	March 2015	Not Relevant
25660033	Create Study	Characterizing heterogeneity in children with and without ADHD based on reward system connectivity.	Developmental cognitive neuroscience	Costa Dias, Taciana G; Iyer, Swathi P; Carpenter, Samuel D; Cary, Robert P; Wilson, Vanessa B; Mitchell, Suzanne H; Nigg, Joel T; Fair, Damien A	February 2015	Not Determined
25512496	Create Study	Large-scale topology and the default mode network in the mouse connectome.	Proceedings of the National Academy of Sciences of the United States of America	Stafford JM, Jarrett BR, Miranda-Dominguez O, Mills BD, Cain N, Mihalas S, Lahvis GP, Lattal KM, Mitchell SH, David SV, Fryer JD, Nigg JT, Fair DA	December 2014	Not Determined
25459874	Create Study	The potential of infant fMRI research and the study of early life stress as a promising exemplar.	Developmental cognitive neuroscience	Graham, Alice M; Pfeifer, Jennifer H; Fisher, Philip A; Lin, Weili; Gao, Wei; Fair, Damien A	April 2015	Not Relevant
25386919	Create Study	Connectotyping: model based fingerprinting of the functional connectome.	PloS one	Miranda-Dominguez, Oscar; Mills, Brian D; Carpenter, Samuel D; Grant, Kathleen A; Kroenke, Christopher D; Nigg, Joel T; Fair, Damien A	January 2014	Not Determined
25312831	Create Study	Sex differences in the neural substrates of spatial working memory during adolescence are not mediated by endogenous testosterone.	Brain research	Alarcón, Gabriela; Cservenka, Anita; Fair, Damien A; Nagel, Bonnie J	December 2014	Not Determined
25307115	Create Study	Research review: Functional brain connectivity and child psychopathology--overview and methodological considerations for investigators new to the field.	Journal of child psychology and psychiatry, and allied disciplines	Matthews M, Fair DA	April 2015	Not Relevant
25233316	Create Study	Unraveling the miswired connectome: a developmental perspective.	Neuron	Di Martino A, Fair DA, Kelly C, Satterthwaite TD, Castellanos FX, Thomason ME, Craddock RC, Luna B, Leventhal BL, Zuo XN, Milham MP	September 2014	Not Determined
25212412	Create Study	Dietary intervention rescues maternal obesity induced behavior deficits and neuroinflammation in offspring.	Journal of neuroinflammation	Kang SS, Kurti A, Fair DA, Fryer JD	September 2014	Not Determined
25116862	Create Study	Structural and functional connectivity of the human brain in autism spectrum disorders and attention-deficit/hyperactivity disorder: A rich club-organization study.	Human brain mapping	Ray, Siddharth; Miller, Meghan; Karalunas, Sarah; Robertson, Charles; Grayson, David S; Cary, Robert P; Hawkey, Elizabeth; Painter, Julia G; Kriz, Daniel; Fombonne, Eric; Nigg, Joel T; Fair, Damien A	December 2014	Not Determined
25006969	Create Study	Subtyping attention-deficit/hyperactivity disorder using temperament dimensions: toward biologically based nosologic criteria.	JAMA psychiatry	Karalunas, Sarah L; Fair, Damien; Musser, Erica D; Aykes, Kamari; Iyer, Swathi P; Nigg, Joel T	September 2014	Not Determined
24890898	Create Study	Emotional processing and brain activity in youth at high risk for alcoholism.	Alcoholism, clinical and experimental research	Cservenka A, Fair DA, Nagel BJ	July 2014	Not Determined
24741045	Create Study	Bridging the gap between the human and macaque connectome: a quantitative comparison of global interspecies structure-function relationships and network topology.	The Journal of neuroscience : the official journal of the Society for Neuroscience	Miranda-Dominguez O, Mills BD, Grayson D, Woodall A, Grant KA, Kroenke CD, Fair DA	April 2014	Not Determined
24642753	Create Study	Organizing heterogeneous samples using community detection of GIMME-derived resting state functional networks.	PloS one	Gates, Kathleen M; Molenaar, Peter C M; Iyer, Swathi P; Nigg, Joel T; Fair, Damien A	January 2014	Not Determined
24505468	Create Study	Structural and functional rich club organization of the brain in children and adults.	PloS one	Grayson, David S; Ray, Siddharth; Carpenter, Samuel; Iyer, Swathi; Dias, Taciana G Costa; Stevens, Corinne; Nigg, Joel T; Fair, Damien A	January 2014	Not Determined
24501348	Create Study	Dietary omega-3 fatty acids modulate large-scale systems organization in the rhesus macaque brain.	The Journal of neuroscience : the official journal of the Society for Neuroscience	Grayson DS, Kroenke CD, Neuringer M, Fair DA	February 2014	Not Determined
24440571	Create Study	Resting state functional connectivity of the nucleus accumbens in youth with a family history of alcoholism.	Psychiatry research	Cservenka A, Casimo K, Fair DA, Nagel BJ	March 2014	Not Determined
24214656	Create Study	Attention deficit hyperactivity disorder.	Current topics in behavioral neurosciences	Matthews, Marguerite; Nigg, Joel T; Fair, Damien A	January 2014	Not Determined
24078018	Create Study	Underconnectivity of the superior temporal sulcus predicts emotion recognition deficits in autism.	Social cognitive and affective neuroscience	Alaerts K, Woolley DG, Steyaert J, Di Martino A, Swinnen SP, Wenderoth N	October 2014	Not Determined
23774715	Create Study	The autism brain imaging data exchange: towards a large-scale evaluation of the intrinsic brain architecture in autism.	Molecular psychiatry	Di Martino, A; Yan, C-G; Li, Q; Denio, E; Castellanos, F X; Alaerts, K; Anderson, J S; Assaf, M; Bookheimer, S Y; Dapretto, M; Deen, B; Delmonte, S; Dinstein, I; Ertl-Wagner, B; Fair, D A; Gallagher, L; Kennedy, D P; Keown, C L; Keysers, C; Lainhart, J E; Lord, C; Luna, B; Menon, V; Minshew, N J; Monk, C S; Mueller, S; Müller, R-A; Nebel, M B; Nigg, J T; O'Hearn, K; Pelphrey, K A; Peltier, S J; Rudie, J D; Sunaert, S; Thioux, M; Tyszka, J M; Uddin, L Q; Verhoeven, J S; Wenderoth, N; Wiggins, J L; Mostofsky, S H; Milham, M P	June 2014	Not Determined
23501054	Create Study	Inferring functional connectivity in MRI using Bayesian network structure learning with a modified PC algorithm.	NeuroImage	Iyer SP, Shafran I, Grayson D, Gates K, Nigg JT, Fair DA	July 2013	Not Determined
23206930	Create Study	Reward circuit connectivity relates to delay discounting in children with attention-deficit/hyperactivity disorder.	European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology	Costa Dias TG, Wilson VB, Bathula DR, Iyer SP, Mills KL, Thurlow BL, Stevens CA, Musser ED, Carpenter SD, Grayson DS, Mitchell SH, Nigg JT, Fair DA	January 2013	Not Determined

helpcenter.collection.publications-tab

Collection - Publications

The number of Publications is displayed in parentheses next to the tab name. Clicking on any of the Publication Titles will open the Publication in a new internet browsing tab.

Collection Owners, Program Officers, and users with Submission or Administrative Privileges for the Collection may mark a publication as either Relevant or Not Relevant in the Status column.

Frequently Asked Questions

How can I determine if a publication is relevant?

Publications are considered relevant to a collection when the data shared is directly related to the project or collection.
Where does the NDA get the publications?

PubMed, an online library containing journals, articles, and medical research. Sponsored by NiH and National Library of Medicine (NLM).

Glossary

Create Study

A link to the Create an NDA Study page that can be clicked to start creating an NDA Study with information such as the title, journal and authors automatically populated.
Not Determined Publication

Indicates that the publication has not yet been reviewed and/or marked as Relevant or Not Relevant so it has not been determined whether an NDA Study is expected.
Not Relevant Publication

A publication that is not based on data related to the aims of the grant/project associated with the Collection or not based on any data such as a review article and, therefore, an NDA Study is not expected to be created.
PubMed

PubMed provides citation information for biomedical and life sciences publications and is managed by the U.S. National Institutes of Health's National Library of Medicine.
PubMed ID

The PUBMed ID is the unique ID number for the publication as recorded in the PubMed database.
Relevant Publication

A publication that is based on data related to the aims of the grant/project associated with the Collection and, therefore, an NDA Study is expected to be created.

Contact NDA Help Desk

Data Expected List: Mandatory Data Structures

These data structures are mandatory for your NDA Collection. Please update the Targeted Enrollment number to accurately represent the number of subjects you expect to submit for the entire study.

For NIMH HIV-related research that involves human research participants: Select the dictionary or dictionaries most appropriate for your research. If your research does not require all three data dictionaries, just ignore the ones you do not need. There is no need to delete extra data dictionaries from your NDA Collection. You can adjust the Targeted Enrollment column in the Data Expected tab to “0” for those unnecessary data dictionaries. At least one of the three data dictionaries must have a non-zero value.

Data Expected	Targeted Enrollment	Initial Submission	Subjects Submitted	Initial Share	Subjects Shared	Status
Research Subject and Pedigree	323	07/15/2013	315	11/15/2013	315	Approved

To create your project's Data Expected list, use the "+New Data Expected" to add or request existing structures and to request new Data Structures that are not in the NDA Data Dictionary.

If the Structure you need already exists, locate it and specify your dates and enrollment when adding it to your Data Expected list. If you require changes to the Structure you need, select the indicator stating "No, it requires changes to meet research needs," and upload a file containing your requested changes.

If the structure you need is not yet defined in the Data Dictionary, you can select "Upload Definition" and attach the necessary materials to request its creation.

When selecting the expected dates for your data, make sure to follow the standard Data Sharing Regimen and choose dates within the date ranges that correspond to your project start and end dates.

Please visit the Completing Your Data Expected Tutorial for more information.

Data Expected List: Data Structures per Research Aims

These data structures are specific to your research aims and should list all data structures in which data will be collected and submitted for this NDA Collection. Please update the Targeted Enrollment number to accurately represent the number of subjects you expect to submit for the entire study.

Data Expected	Targeted Enrollment	Initial Submission	Subjects Submitted	Initial Share	Subjects Shared	Status
ADOS	323	01/15/2015	106	05/15/2015	106	Approved
ADI-R	323	01/15/2015	137	05/15/2015	137	Approved
Childrens Depression Inventory	120	01/15/2015	84	05/15/2015	84	Approved
Social Communication Questionnaire (SCQ)	323	01/15/2015	200	05/15/2015	200	Approved
Demographics	323	01/15/2015	290	05/15/2015	290	Approved
Childrens Communication Checklist-2 (CCC-2)	323	01/15/2015	339	05/15/2015	339	Approved
Behavior Assessment System for Children (BASC)	323	01/15/2015	213	05/15/2015	213	Approved
Processed MRI Data	92	01/15/2015	90	10/20/2020	90	Approved
Conners	323	01/15/2015	285	05/15/2015	282	Approved
Kiddie-Sads (K-SADS)	323	01/15/2015	102	05/15/2015	102	Approved
Temperament in Middle Childhood Questionnaire	120	01/15/2015	104	10/20/2020	0	Approved
ADHD Rating Scale	323	07/15/2013	291	11/15/2013	291	Approved
Imaging (Structural, fMRI, DTI, PET, microscopy)	323	01/15/2015	94	05/15/2015	94	Approved
Broad Psychopathology Form	323	01/15/2015	307	05/15/2015	307	Approved
Multidimensional Anxiety Scale for Children (MASC)	120	01/15/2015	80	05/15/2015	80	Approved
Strengths and Weakness of ADHD Symptoms and Normal Behavior	120	01/15/2015	104	10/20/2020	0	Approved

Structure not yet defined

No Status history for this Data Expected has been recorded yet

helpcenter.collection.data-expected-tab

Collection - Data Expected

The Data Expected tab displays the list of all data that NDA expects to receive in association with the Collection as defined by the contributing researcher, as well as the dates for the expected initial upload of the data, and when it is first expected to be shared, or with the research community. Above the primary table of Data Expected, any publications determined to be relevant to the data within the Collection are also displayed - members of the contributing research group can use these to define NDA Studies, connecting those papers to underlying data in NDA.

The tab is used both as a reference for those accessing shared data, providing information on what is expected and when it will be shared, and as the primary tracking mechanism for contributing projects. It is used by both contributing primary researchers, secondary researchers, and NIH Program and Grants Management staff.

Researchers who are starting their project need to update their Data Expected list to include all the Data Structures they are collecting under their grant and set their initial submission and sharing schedule according to the NDA Data Sharing Regimen.

To add existing Data Structures from the Data Dictionary, to request new Data Structure that are not in the Dictionary, or to request changes to existing Data Structures, click "+New Data Expected".

For step-by-step instructions on how to add existing Data Structures, request changes to an existing Structure, or request a new Data Structure, please visit the Completing Your Data Expected Tutorial.

If you are a contributing researcher creating this list for the first time, or making changes to the list as your project progress, please note the following:

Although items you add to the list and changes you make are displayed, they are not committed to the system until you Save the entire page using the "Save" button at the bottom of your screen. Please Save after every change to ensure none of your work is lost.
If you attempt to add a new structure, the title you provide must be unique - if another structure exists with the same name your change will fail.
Adding a new structure to this list is the only way to request the creation of a new Data Dictionary definition.

Frequently Asked Questions

What is an NDA Data Structure?

An NDA Data Structure is comprised of multiple Data Elements to make up an electronic definition of an assessment, measure, questionnaire, etc will have a corresponding Data Structure.
What is the NDA Data Dictionary?

The NDA Data Dictionary is comprised of electronic definitions known as Data Structures.

Glossary

Analyzed Data

Data specific to the primary aims of the research being conducted (e.g. outcome measures, other dependent variables, observations, laboratory results, analyzed images, volumetric data, etc.) including processed images.
Data Item

Items listed on the Data Expected list in the Collection which may be an individual and discrete Data Structure, Data Structure Category, or Data Structure Group.
Data Structure

A defined organization and group of Data Elements to represent an electronic definition of a measure, assessment, questionnaire, or collection of data points. Data structures that have been defined in the NDA Data Dictionary are available at https://nda.nih.gov/general-query.html?q=query=data-structure
Data Structure Category

An NDA term describing the affiliation of a Data Structure to a Category, which may be disease/disorder or diagnosis related (Depression, ADHD, Psychosis), specific to data type (MRI, eye tracking, omics), or type of data (physical exam, IQ).
Data Structure Group

A Data Item listed on the Data Expected tab of a Collection that indicates a group of Data Structures (e.g., ADOS or SCID) for which data may be submitted instead of a specific Data Structure identified by version, module, edition, etc. For example, the ADOS Data Structure Category includes every ADOS Data Structure such as ADOS Module 1, ADOS Module 2, ADOS Module 1 - 2nd Edition, etc. The SCID Data Structure Group includes every SCID Data Structure such as SCID Mania, SCID V Mania, SCID PTSD, SCID-V Diagnosis, and more.
Evaluated Data

A new Data Structure category, Evaluated Data is analyzed data resulting from the use of computational pipelines in the Cloud and can be uploaded directly back to a miNDAR database. Evaluated Data is expected to be listed as a Data Item in the Collection's Data Expected Tab.
Imaging Data

Imaging+ is an NDA term which encompasses all imaging related data including, but not limited to, images (DTI, MRI, PET, Structural, Spectroscopy, etc.) as well as neurosignal data (EEG, fMRI, MEG, EGG, eye tracking, etc.) and Evaluated Data.
Initial Share Date

Initial Submission and Initial Share dates should be populated according to the NDA Data Sharing Terms and Conditions. Any modifications to these will go through the approval processes outlined above. Data will be shared with authorized users upon publication (via an NDA Study) or 1-2 years after the grant end date specified on the first Notice of Award, as defined in the applicable Data Sharing Terms and Conditions.
Initial Submission Date

Initial Submission and Initial Share dates should be populated according to these NDA Data Sharing Terms and Conditions. Any modifications to these will go through the approval processes outlined above. Data for all subjects is not expected on the Initial Submission Date and modifications may be made as necessary based on the project's conduct.
Research Subject and Pedigree

An NDA created Data Structure used to convey basic information about the subject such as demographics, pedigree (links family GUIDs), diagnosis/phenotype, and sample location that are critical to allow for easier querying of shared data.
Submission Cycle

The NDA has two Submission Cycles per year - January 15 and July 15.
Submission Exemption

An interface to notify NDA that data may not be submitted during the upcoming/current submission cycle.

Contact NDA Help Desk

Collection Owners and those with Collection Administrator permission, may edit a collection. The following is currently available for Edit on this page:

Associated Studies

Studies that have been defined using data from a Collection are important criteria to determine the value of data shared. The number of subjects column displays the counts from this Collection that are included in a Study, out of the total number of subjects in that study. The Data Use column represents whether or not the study is a primary analysis of the data or a secondary analysis. State indicates whether the study is private or shared with the research community.

Study NameFilter by Study Name	AbstractFilter by Abstract	Collection/Study SubjectsFilter by Collection/Study Subjects	Data UsageFilter by Data Usage	StateFilter by State
Examining Diagnostic Trends and Gender Differences in the ADOS-II	Approximately 3–4 boys for every girl meet the clinical criteria for autism in studies of community diagnostic patterns and studies of autism using samples of convenience. However, girls with autism have been hypothesized to be underdiagnosed, possibly because they may present with differing symptom profiles as compared to boys. This secondary data analysis used the National Database of Autism Research (NDAR) to examine how gender and symptom profiles are associated with one another in a gold standard assessment of autism symptoms, the Autism Diagnostic Observation Schedule II (ADOS-II; Lord, C., Luyster, R., Guthrie, W., & Pickles A. (2012a). Patterns of developmental trajectories in toddlers with autism spectrum disorder. Journal of Consulting and Clinical Psychology, 80(3):477–489. https://doi.org/10.1037/a0027214. Epub 2012 Apr 16. PMID: 22506796, PMCID: PMC3365612). ADOS-II scores from 6183 children ages 6–14 years from 78 different studies in the NDAR indicated that gender was a significant predictor of total algorithm, restrictive and repetitive behavioral, and social communicative difficulties composite severity scores. These findings suggest that gender differences in ADOS scores are common in many samples and may reflect on current diagnostic practices.	89/5615	Secondary Analysis	Shared
Gender Differences: Confirmatory Factor Analysis of the ADOS-II	Purpose Recent research has suggested that autism may present differently in girls compared to boys, encouraging the exploration of a sex-differential diagnostic criteria. Gender differences in diagnostic assessments have been shown on the ADOS-II, such that, on average, females score significantly lower than males on all scales and are less likely to show atypicality on most items related to social communicative difficulties. Yet, gender differences in the latent structure of instruments like the ADOS-II have not been examined systematically. Methods As such, this secondary data analysis examined 4,100 youth diagnosed with autism (Mage = 9.9, 813 female & 3287 male) examined item response trends by gender on the ADOS-II Module 3. Results Multi-Group Confirmatory Factor Analysis results show that the factor loadings of four ADOS-II items differ across the genders. One SCD item and one RRB item are strongly related to the latent factor in the female group, while two RRB items have larger factor loadings in the male group. Conclusion The assumption of an identical latent factor structure for the ADOS-II Module 3 for males and females might not be justifiable. Possible diagnostic implications are discussed.	89/5615	Secondary Analysis	Shared
Investigating autism etiology and heterogeneity by decision tree algorithm	Autism spectrum disorder (ASD) is a neurodevelopmental disorder that causes deficits in cognition, communication and social skills. ASD, however, is a highly heterogeneous disorder. This heterogeneity has made identifying the etiology of ASD a particularly difficult challenge, as patients exhibit a wide spectrum of symptoms without any unifying genetic or environmental factors to account for the disorder. For better understanding of ASD, it is paramount to identify potential genetic and environmental risk factors that are comorbid with it. Identifying such factors is of great importance to determine potential causes for the disorder, and understand its heterogeneity. Existing large-scale datasets offer an opportunity for computer scientists to undertake this task by utilizing machine learning to reliably and efficiently obtain insight about potential ASD risk factors, which would in turn assist in guiding research in the field. In this study, decision tree algorithms were utilized to analyze related factors in datasets obtained from the National Database for Autism Research (NDAR) consisting of nearly 3000 individuals. We were able to identify 15 medical conditions that were highly associated with ASD diagnoses in patients; furthermore, we extended our analysis to the family medical history of patients and we report six potentially hereditary medical conditions associated with ASD. Associations reported had a 90% accuracy. Meanwhile, gender comparisons highlighted conditions that were unique to each gender and others that overlapped. Those findings were validated by the academic literature, thus opening the way for new directions for the use of decision tree algorithms to further understand the etiology of autism.	63/3382	Secondary Analysis	Shared

* Data not on individual level

helpcenter.collection.associated-studies-tab

Collection - Associated Studies

Clicking on the Study Title will open the study details in a new internet browser tab. The Abstract is available for viewing, providing the background explanation of the study, as provided by the Collection Owner.

Primary v. Secondary Analysis: The Data Usage column will have one of these two choices. An associated study that is listed as being used for Primary Analysis indicates at least some and potentially all of the data used was originally collected by the creator of the NDA Study. Secondary Analysis indicates the Study owner was not involved in the collection of data, and may be used as supporting data.

Private v. Shared State: Studies that remain private indicate the associated study is only available to users who are able to access the collection. A shared study is accessible to the general public.

Frequently Asked Questions

How do I associate a study to my collection?

Studies are associated to the Collection automatically when the data is defined in the Study.

Glossary

Associated Studies Tab

A tab in a Collection that lists the NDA Studies that have been created using data from that Collection including both Primary and Secondary Analysis NDA Studies.

Contact NDA Help Desk

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