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This is a U.S. Government computer system, which may be accessed and used only for authorized Government business by authorized personnel. Unauthorized access or use of this computer system may subject violators to criminal, civil, and/or administrative action. All information on this computer system may be intercepted, recorded, read, copied, and disclosed by and to authorized personnel for official purposes, including criminal investigations. Such information includes sensitive data encrypted to comply with confidentiality and privacy requirements. Access or use of this computer system by any person, whether authorized or unauthorized, constitutes consent to these terms. There is no right of privacy in this system.

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NIMH Data Archive
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View Cohort
        helpcenter.ndastudy.view-cohort

        NDA Help Center

        NDA Study - View Cohort

        The View Cohort shows the Study cohort characteristics which will includes the name, type, sex and age in months range criteria. Note that age and sex restrict the data that can be added to the cohort. Medical criteria and phenotype are also included. Of particular importance on this page are any comments related to included subjects, which may be different than published results, often attributed to data sharing consent.

        Frequently Asked Questions

        • How do I know the characteristics of the cohort?
          The appropriate Medical Criteria, Phenotype, and Sub Type defined by the Study Owner are highlighted. The option trees are automatically expanded so the highlighted options are immediately viewable.

        Glossary

        • Age Range
          Age is expressed in months from 0 (birth) to 1200 (100 years old).
        • Medical Criteria
          NDA defines Medical Criteria as a diagnostically based determination of an individual's disease or condition.
        • Phenotype
          NDA defines Phenotype as any physical, morphologic, or biochemical characteristics that are observable in an individual.
        • Sub Types
          NDA defines Sub Type as a subordinate condition or disease that further characterizes an individual.
        • Cohort Name
          A user defined name for the cohort with a 200 character limit.
        • Cohort Type
          Cohort Type options include Baseline, Control, and Test.
        • Cohort Comments
          Comments further characterize the cohort beyond the options provided in the interface to define the cohort.
        • Cohort Subjects
          The Cohort Subjects provides the number of unique subjects for whom data have been associated with the cohort.
        • Cohort
          Summarizes the characteristics of a group of research subjects. The subject count is noted in parentheses.
        Contact NDA Help Desk
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        Study DOI
        Study DOI Status Info
        • DOI: 10.15154/4sxe-qh09
        • DataCite Status: Findable
        • NDAR Status: Registered
        • DOI Registered with DataCite
        • Public URL Resolves at DOI
        Edit Subjects Dialog
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        Ingrid Tien istien@g.ucla.edu Analysis Shared
        Click for more info Tien, Ingrid; Tien, Ingrid; Kim, Junok; Johnson, Amanda; Wood, Jeffrey
        Purpose Recent research has suggested that autism may present differently in girls compared to boys, encouraging the exploration of a sex-differential diagnostic criteria. Gender differences in diagnostic assessments have been shown on the ADOS-II, such that, on average, females score significantly lower than males on all scales and are less likely to show atypicality on most items related to social communicative difficulties. Yet, gender differences in the latent structure of instruments like the ADOS-II have not been examined systematically. Methods As such, this secondary data analysis examined 4,100 youth diagnosed with autism (Mage = 9.9, 813 female & 3287 male) examined item response trends by gender on the ADOS-II Module 3. Results Multi-Group Confirmatory Factor Analysis results show that the factor loadings of four ADOS-II items differ across the genders. One SCD item and one RRB item are strongly related to the latent factor in the female group, while two RRB items have larger factor loadings in the male group. Conclusion The assumption of an identical latent factor structure for the ADOS-II Module 3 for males and females might not be justifiable. Possible diagnostic implications are discussed.
        10.15154/4sxe-qh09
        Click for more info Secondary Analysis
        Click for more info
        IDCollectionPermission GroupSubjects
        2288 The Autism Biomarkers Consortium for Clinical Trials NIMH Data Archive424
        2866 Investigating Social Competence in Youth with Autism: A Multisite RCT NIMH Data Archive237
        2976 Autism Genetics Phase II: Increasing representation of human diversity NIMH Data Archive235
        2251 Developmental Synaptopathies Associated with TSC, PTEN and SHANK3 Mutations NIMH Data Archive183
        1950 Effectiveness and Implementation of a Mental Health Intervention for ASD NIMH Data Archive173
        2009 Study of Oxytocin in Autism to Improve Reciprocal Social Behaviors (SOARS-B) NIMH Data Archive171
        1 UIC ACE: Translational Studies of Insistence on Sameness in Autism NIMH Data Archive167
        2021 Multimodal Developmental Neurogenetics of Females with ASD NIMH Data Archive162
        2683 Examining Stress and Arousal Across Pubertal Development in ASD NIMH Data Archive150
        2076 1/3 to 3/3 Treatment of anxiety in autism spectrum disorder NIMH Data Archive149
        2292 Molecular Mechanisms of Atypical Habituation in Autism Spectrum Disorders NIMH Data Archive143
        2775 Brain and Behavior Study of Autism from Infancy through School Age NIMH Data Archive130
        2368 Clinical and Immunological Investigations of Subtypes of Autism NIMH Data Archive122
        2030 Electrophysiological Response to Executive Control Training in Autism NIMH Data Archive100
        2013 Magnetoencephalographic studies of lexical processing and abstraction in autism NIMH Data Archive97
        2421 Optimizing Prediction of Social Deficits in Autism Spectrum Disorders NIMH Data Archive97
        2011 Toward Outcome Measurement of Anxiety in Youth with Autism Spectrum Disorders NIMH Data Archive95
        2253 Neurophenotypic Trajectories and Behavioral Outcomes in Autism Spectrum Disorder NIMH Data Archive95
        3058 Behavioral Inflexibility in IDD Outcome Measurement NIMH Data Archive95
        2900 Functional Connectivity in Developmental Delay: Shared Etiology and Differential Outcomes NIMH Data Archive93
        2821 Cellular, molecular, and functional imaging approaches to understanding early neurodevelopment in autism NIMH Data Archive91
        2322 Electrophysiologic Studies of Language Impairment in ASD (Years 6-10) NIMH Data Archive90
        1955 Characterizing mechanistic heterogeneity across ADHD and Autism NIMH Data Archive89
        2036 Intervention effects of intensity and delivery style for toddlers with ASD NIMH Data Archive85
        2070 Eyeblink conditioning in school-aged children with ASD NIMH Data Archive83
        2020 Adaptive Interventions for Minimally Verbal Children with ASD in the Community NIMH Data Archive81
        2415 Sensory Integration Therapy in Autism: Mechanisms and Effectiveness NIMH Data Archive80
        2555 A longitudinal study of brain development in children with autism NIMH Data Archive79
        2857 Brain trajectories in ADHD NIMH Data Archive77
        2776 Co-occurring ADHD in young children with ASD: Precursors, detection, neural signatures, and early treatment NIMH Data Archive74
        2460 Emergence, Stability and Predictors of Anxiety in Fragile X Syndrome NIMH Data Archive73
        2442 Emergence and Stability of Autism in Fragile X Syndrome NIMH Data Archive73
        2351 Arousal Tendencies and Individual Differences in Children with Autism Spectrum Disorder NIMH Data Archive70
        2093 Sporadic Mutations and Autism Spectrum Disorders NIMH Data Archive59
        2559 Neural Mechanisms of CBT for Anxiety in Children with Autism Spectrum Disorder NIMH Data Archive58
        2179 Neural markers of shared gaze during simulated social interactions in ASD \-Modal Automated Assessment of Behavior during Social Interactions in Children with ASD NIMH Data Archive57
        2561 Somatosensory Inhibitory Dysfunction in Autism Spectrum Disorder NIMH Data Archive56
        2765 A Web Based Tool to Assess Social Cognition in ASD NIMH Data Archive55
        2063 Epidemiological Research on Autism in Jamaica - Phase II NIMH Data Archive54
        1985 Evaluating the Time-Dependent Unfolding of Social Interactions in Children with Autism NIMH Data Archive50
        2025 Minimally Verbal ASD: From Basic Mechanisms to Innovative Interventions NIMH Data Archive50
        2052 Peers, Play and Performance to Improve Social Interaction in Autism NIMH Data Archive48
        2707 MEG Studies of Auditory Processing in Minimally/Non-Verbal Children with ASD and Intellectual Disabilities NIMH Data Archive46
        2834 Neuronal Correlates of Autistic Traits in ADHD and Autism NIMH Data Archive45
        2342 Cognitive and Neural Flexibility in Autism NIMH Data Archive45
        2386 Efficacy of the Direct Instruction Language for Learning Program to Promote Expressive and Receptive Language in Children with Autism Spectrum Disorder NIMH Data Archive41
        2026 Biomarkers of Developmental Trajectories and Treatment in ASD NIMH Data Archive41
        2828 Sensory consequences of action in children with autism spectrum disorders NIMH Data Archive39
        2260 Effects of Social Gaze Training on Brain and Behavior in Fragile X Syndrome NIMH Data Archive38
        2771 Emergent Gaze Perception in Autism Spectrum Disorder NIMH Data Archive38
        2072 Intrinsic Brain Architecture of Young Children with Autism While Awake and Asleep NIMH Data Archive37
        2676 Intranasal vasopressin treatment in children with autism NIMH Data Archive35
        2799 A Novel Framework for Impaired Imitation in ASD NIMH Data Archive35
        2845 Attentional, temperamental, and physiological process underlying anxiety in preschoolers with ASD NIMH Data Archive32
        2075 Mapping Thalamocortical Networks Across Development in ASD NIMH Data Archive32
        2394 Brain Network Dynamics Contributing to Atypical Social Interaction in Autism NIMH Data Archive30
        2524 Effects of AFQ056 on Language Learning in Young Children with Fragile X Syndrome (FXS) NIMH Data Archive28
        2441 Structural and Functional Characteristics of XYY - Relationship to ASD NIMH Data Archive27
        4306 Statistical approaches to improving functional connectivity estimates with an application to autism NIMH Data Archive27
        2281 Predictors of Cognitive Development in Autism Spectrum Disorder NIMH Data Archive26
        2423 Using Serious Games to Improve Social Skills in Autism (SAGA) NIMH Data Archive26
        2254 The neurobiological basis of heterogeneous social and motor deficits in ASD NIMH Data Archive26
        2197 The role of vasopressin in the social deficits of autism NIMH Data Archive26
        2129 Biological Determinants of Brain Variation in Autism NIMH Data Archive25
        3022 Electrophysiological Markers for Interventions in Phelan-McDermid Syndrome and Idiopathic Autism NIMH Data Archive25
        2262 Comparing Behavioral Assessments Using Telehealth for Children with Autism NIMH Data Archive23
        2060 Dysfunction of Sensory Inhibition in Autism NIMH Data Archive23
        2928 Understanding Attentional Strengths and Weaknesses in Autism Spectrum Disorder NIMH Data Archive22
        2095 The neurophysiology of sensory processing and multisensory integration in ASD NIMH Data Archive22
        2591 Quantification of Predictive Motor Impairments in Individuals with ASD NIMH Data Archive22
        1958 A Family-Genetic Study of Autism and Fragile X Syndrome NIMH Data Archive22
        2656 Developmental trajectory of anxiety, avoidance, and arousal in girls with the FMR1 full mutation NIMH Data Archive22
        2773 Teaching Academic Success Skills to Middle School Students with Autism Spectrum Disorders (ASD) with Executive Functioning Deficits NIMH Data Archive22
        2933 Elucidating Genetic Components of Autism and Related Disorders NIMH Data Archive21
        2566 Direct Examination of Imitation-Based Learning in Autism NIMH Data Archive21
        2614 Modeling the Human Neuronal Phenotype of the Schizophrenia-Associated 3q29 deletion NIMH Data Archive21
        3081 Neurophysiological and neuroanatomical processes related to Autism Spectrum Disorder in Neurofibromatosis Type 1 NIMH Data Archive21
        2272 Developing an Automated Emotion Training System NIMH Data Archive20
        2710 Functional connectivity substrates of social and non-social deficits in ASD NIMH Data Archive18
        2285 Integrity and Dynamic Processing Efficiency of Networks in ASD NIMH Data Archive18
        2354 Neurodevelopment of cognitive control in autism: adolescence to young adulthood NIMH Data Archive18
        2316 Quantitative Measurements of Cortical Excitability in Neurodevelopmental Disorder NIMH Data Archive18
        2062 Verbal/non-verbal asynchrony in adolescents with high-functioning Autism NIMH Data Archive17
        3088 Brainstem Contributions to Sensorimotor and Core Symptoms in Children with Autism Spectrum Disorder NIMH Data Archive16
        2777 Center for the Development of Phenotype-Based Treatments of Autism Spectrum Disorder NIMH Data Archive15
        2250 A feasibility study for prevention and safety training for children with autism NIMH Data Archive14
        2017 Wireless EEG System for Training Attention and Eye Movement in ASD NIMH Data Archive14
        2510 Kansas Intellectual and Developmental Disabilities Research Center NIMH Data Archive12
        2706 Thalamic activity and structure and surface neural oscillations in autism NIMH Data Archive12
        2711 Motor abnormalities and functional brain mechanisms in autism spectrum disorder NIMH Data Archive11
        2556 Behavioral Economic Measures of Sensitivity to Social Reward in Children with ASD NIMH Data Archive7
        1900 Neurobehavioral Research on Infants at Risk for SLI and Autism NDA-IRB-PUB-COL7
        2358 Neural networks for attention to internal and external sensory cues in ASD NIMH Data Archive7
        2702 The Autism MEAL Plan: A Parent Training Curriculum to Manage Eating Aversions and Limited Variety among Children with Autism NIMH Data Archive5
        1965 Longitudinal Studies of Autism Spectrum Disorders: From 2 to 23 NIMH Data Archive5
        2114 Early identification and service linkage for urban children with autism NIMH Data Archive5
        2761 Charting the trajectory of executive control in autism in order to optimize delivery of intervention NIMH Data Archive5
        2169 Human Clinical Trial of IGF-1 in Children with Idiopathic ASD NIMH Data Archive4
        2080 Smart Early Screening for Autism and Communication Disorders in Primary Care NIMH Data Archive2
        3471 Surviving and Thriving in the Real World: A Daily Living Skills Intervention for Adolescents with Autism Spectrum Disorder NIMH Data Archive2
        2192 Piloting Treatment with Insulin-Like Growth Factor-1 in Phelan-McDermid Syndrome NIMH Data Archive1
        3111 Brain Network Development in Normal and Autistic Children NIMH Data Archive1
        2108 Neural Phenotypes of Females with Autism Spectrum Disorder NIMH Data Archive1
        2440 Development of Behavioral and Neural Biomarkers for Autism Spectrum Disorder Using a Genetically Defined Subtype NIMH Data Archive1
        3183 Pilot RCT of a Daily Living Skills Intervention for Adolescents with Autism Spectrum Disorder in the Last 2 Years of High School NIMH Data Archive1
        2006 Impairments of Theory of Mind disrupt patterns of brain activity NIMH Data Archive1
        2266 Inhibitory dysfunction in autism NIMH Data Archive1
        2572 Development of a novel neurotechnology to promote emotion recognition in autism NIMH Data Archive1
        2767 Cycles of Social Contingency in Autism: Pivotal Transitions that Shape Infant Brain-Behavior Development in Human & Model Systems NIMH Data Archive1
        2012 Optimization of Fidelity Procedures for Pivotal Response Training in Autism NIMH Data Archive1
        Analysis
        Age: 72 to 168 months
        Sex: Both
        helpcenter.ndastudy.summary-tab

        NDA Help Center

        NDA Study - Summary Tab

        An NDA Study describes an analysis, pipeline result, or curated data release - including the cohorts, measures, and methods - referencing the underlying source data in the NDA. Once the data is referenced and the study is shared, the underlying data will not change. It will be immutable allowing others to access those data without change into near perpetuity. Only the assessments (i.e. typically rows in a database) and outcome measures (i.e. columns in a database) included in the study are shared. By sharing data this way (e.g. specific outcome measures by subject/timepoint) an ongoing project's other unpublished data - typically other research aims - will remain embargoed according to a project's established data sharing schedule (see collection).

        When a study is created, a Digital Object Identifier (DOI) is reserved by the NDA, but will not be active. Once the study is shared, the DOI will then be issued and if associated with a publication, the NDA DOI will be linked to the publication's DOI.

        Frequently Asked Questions

        • How can I get access to an NDA Study if I am involved in creating/modifying the NDA Study?
          The individual listed as an Investigator on the General tab of the NDA Collection and any individuals defined as administrators can be provided this privilege. When the study is shared, all of those that have approved access to the data are given read-only access.

        Glossary

        • Abstract
          The Abstract of the publication or other public disclosure of analysis results. The publication abstract is automatically imported when creating a new NDA Study from a Create Study link associated with a Publication listed in a Collection. The field is editable.
        • Documents
          Provides links to additional documentation to help explain the NDA Study.
        • Cohort
          Summarizes the characteristics of a group of research subjects. The subject count is noted in parentheses.
        • Data Analysis
          Summarizes the Data Analysis methods used.
        • Data Usage
          Identifies the NDA Study as a Primary Analysis or Secondary Analysis.
        • Digital Object Identifier (DOI)
          A persistent and unique identifier that is issued for each NDA Study that may increase the visibility of a researcher's work. Authors are expected to reference the location of data in the publication using the DOI.
        • Download Button
          Adds all data from the current Collection or NDA Study to the Filter Cart.
        • Investigators
          The authors of the publication or other public disclosure of analysis results. The publication's authors are automatically imported when creating a new NDA Study from a Create Study link associated with a Publication listed in a Collection. The field is editable and uses a last name, first name format with multiple names separated by semicolons.
        • Primary Analysis
          Primary Analysis is one of the Data Use types NDA recognizes for NDA Studies. It indicates that the NDA Study's creator was involved in the collection of the data (in whole or in part) used in the NDA Study. In other words, at least some and potentially all of the data used was originally collected by the creator of the NDA Study. A Primary Analysis Study.
        • NDA Study Owner
          The NDA user, who does not necessarily have to be one of the Investigators listed in the NDA Study, primarily involved in creating the NDA Study who is serving as the point of contact. The NDA user who creates the NDA Study is automatically assigned as the Study Owner.
        • Private
          The term 'Private' generally means not available to others; however, there are some slightly different meanings based on what is Private. The default state for an NDA Collection, NDA Study, Supporting Documentation, and data is Private and, therefore, accessible only to those users with appropriate Privileges so it will not be viewable and searchable publicly. A Collection may be Shared while the data and Supporting Documentation remain Private.
        • Results
          Provides a link to the publication or other public disclosure of analysis results defined in the NDA Study.
        • Secondary Analysis
          Secondary Analysis is one of the Data Use types NDA recognizes for NDA Studies. It indicates that the NDA Study's creator was not involved in the collection of the data (in whole or in part) used in the NDA Study, but was involved in the analysis of those data. In other words, none of the data used was originally collected by the creator of the NDA Study. A Secondary Analysis Study will provide an Attribution Report listing the Collections and the researchers responsible for collecting and depositing the original data.
        • Study Type
          The NDA Study Type can be either Analysis (i.e. often associated with a computational pipeline), Clinical Trial, Finding (i.e. a result associated with a publication, or Release (i.e. a dataset release, often annually) to indicate the type of work defined in the NDA Study. Studies, once shared do not change.
        • Analysis Study Type
          The Analysis Study Type is primarily used to share a pipeline; however, it could be used to share a statistical analysis or method.
        • Release Study Type
          A static, curated data set.
        • Finding Study Type
          The Finding Study Type associates data to a publication or some type of result.
        • Clinical Trial Study Type
          A Clinical Trial Study is a finding specific to a clinical trial.
        • Study ID Number
          The Study ID number is a unique three digit number routinely expressed as S### that is assigned by the NDA.
        • Study State
          The Study State indicates whether the Study is viewable, searchable, and if the associated data can be accessed by users with appropriate data access Permissions. The default Study State is Private, which means that only the Collection Owner and users with Read Only Privileges. Only the Study Owner can Share the Study.
        • Study Title
          The Study Title is generally the title of the publication or other public disclosure of analysis results. The publication title is automatically imported when creating a new NDA Study from a Create Study link associated with a Publication listed in a Collection. The field is editable.
        • Edit Button
          The Edit Button allows a user to modify or add information once authenticated and if the user has appropriate permissions.
        • Return Button (Study)
          The Return Button brings the user back to the Data from Papers page.
        • Sex
          Sex is defined at birth and can only be Male or Female. In some places in the NDA, we incorrectly used the data_element name of Gender. Users are encouraged to review definitions and not make assumptions based upon a data element name.
        • Data Use Limitations
          Data Use Limitations (DULs) describe the appropriate secondary use of a dataset and are based on the original informed consent of a research participant. NDA only accepts consent-based data use limitations defined by the NIH Office of Science Policy.
        • Permission Group
          Access to shared record-level data in NDA is provisioned at the level of a Permission Group. NDA Permission Groups consist of one or multiple NDA Collections that contain data with the same subject consents.
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