National Institute of Mental Health Data Archive (NDA) Sign In
National Institute of Mental Health Data Archive (NDA) Sign In

Success! An email is on its way!

Please check your email to complete the linking process. The link you receive is only valid for 30 minutes.

Check your spam or junk folder if you do not receive the email in the next few minutes.

Warning Notice This is a U.S. Government computer system, which may be accessed and used only for authorized Government business by authorized personnel. Unauthorized access or use of this computer system may subject violators to criminal, civil, and/or administrative action. All information on this computer system may be intercepted, recorded, read, copied, and disclosed by and to authorized personnel for official purposes, including criminal investigations. Such information includes sensitive data encrypted to comply with confidentiality and privacy requirements. Access or use of this computer system by any person, whether authorized or unauthorized, constitutes consent to these terms. There is no right of privacy in this system.
Create or Link an Existing NDA Account
NIMH Data Archive (NDA) Sign In or Create An Account
Update Password

You have logged in with a temporary password. Please update your password. Passwords must contain 8 or more characters and must contain at least 3 of the following types of characters:

  • Uppercase
  • Lowercase
  • Numbers
  • Special Characters limited to: %,_,!,@,#,$,-,%,&,+,=,),(,*,^,:,;

Subscribe to our mailing list

Mailing List(s)
Email Format

You are now leaving the NIMH Data Archive (NDA) web site to go to:

Click on the address above if the page does not change within 10 seconds.


NDA is not responsible for the content of this external site and does not monitor other web sites for accuracy.

Accept Terms
Data Access Terms - Decline Terms

Are you sure you want to cancel? This will decline terms and you will not be authorized for access.

1 Numbers reported are subjects by age
New Trial
New Project

Format should be in the following format: Activity Code, Institute Abbreviation, and Serial Number. Grant Type, Support Year, and Suffix should be excluded. For example, grant 1R01MH123456-01A1 should be entered R01MH123456

Please select an experiment type below

Collection - Use Existing Experiment
To associate an experiment to the current collection, just select an axperiment from the table below then click the associate experiment button to persist your changes (saving the collection is not required). Note that once an experiment has been associated to two or more collections, the experiment will not longer be editable.

The table search feature is case insensitive and targets the experiment id, experiment name and experiment type columns. The experiment id is searched only when the search term entered is a number, and filtered using a startsWith comparison. When the search term is not numeric the experiment name is used to filter the results.
SelectExperiment IdExperiment NameExperiment Type
Created On
475MB1-10 (CHOP)Omics06/07/2016
490Illumina Infinium PsychArray BeadChip AssayOmics07/07/2016
501PharmacoBOLD Resting StatefMRI07/27/2016
509ABC-CT Resting v2EEG08/18/2016
13Comparison of FI expression in Autistic and Neurotypical Homo SapiensOmics12/28/2010
18AGRE/Broad Affymetrix 5.0 Genotype ExperimentOmics01/06/2011
22Stitching PCR SequencingOmics02/14/2011
29Microarray family 03 (father, mother, sibling)Omics03/24/2011
37Standard paired-end sequencing of BCRsOmics04/19/2011
38Illumina Mate-Pair BCR sequencingOmics04/19/2011
39Custom Jumping LibrariesOmics04/19/2011
40Custom CapBPOmics04/19/2011
43Autism brain sample genotyping, IlluminaOmics05/16/2011
47ARRA Autism Sequencing Collaboration at Baylor. SOLiD 4 SystemOmics08/01/2011
53AGRE Omni1-quadOmics10/11/2011
59AGP genotypingOmics04/03/2012
60Ultradeep 454 sequencing of synaptic genes from postmortem cerebella of individuals with ASD and neurotypical controlsOmics06/23/2012
63Microemulsion PCR and Targeted Resequencing for Variant Detection in ASDOmics07/20/2012
76Whole Genome Sequencing in Autism FamiliesOmics01/03/2013
90Genotyped IAN SamplesOmics07/09/2013
91NJLAGS Axiom Genotyping ArrayOmics07/16/2013
93AGP genotyping (CNV)Omics09/06/2013
106Longitudinal Sleep Study. H20 200. Channel set 2EEG11/07/2013
107Longitudinal Sleep Study. H20 200. Channel set 3EEG11/07/2013
108Longitudinal Sleep Study. AURA 200EEG11/07/2013
105Longitudinal Sleep Study. H20 200. Channel set 1EEG11/07/2013
109Longitudinal Sleep Study. AURA 400EEG11/07/2013
116Gene Expression Analysis WG-6Omics01/07/2014
131Jeste Lab UCLA ACEii: Charlie Brown and Sesame Street - Project 1Eye Tracking02/27/2014
132Jeste Lab UCLA ACEii: Animacy - Project 1Eye Tracking02/27/2014
133Jeste Lab UCLA ACEii: Mom Stranger - Project 2Eye Tracking02/27/2014
134Jeste Lab UCLA ACEii: Face Emotion - Project 3Eye Tracking02/27/2014
151Candidate Gene Identification in familial AutismOmics06/09/2014
152NJLAGS Whole Genome SequencingOmics07/01/2014
154Math Autism Study - Vinod MenonfMRI07/15/2014
160syllable contrastEEG07/29/2014
167School-age naturalistic stimuliEye Tracking09/19/2014
44AGRE/Broad Affymetrix 5.0 Genotype ExperimentOmics06/27/2011
45Exome Sequencing of 20 Sporadic Cases of Autism Spectrum DisorderOmics07/15/2011
Collection - Add Experiment
Add Supporting Documentation
Select File

To add an existing Data Structure, enter its title in the search bar. If you need to request changes, select the indicator "No, it requires changes to meet research needs" after selecting the Structure, and upload the file with the request changes specific to the selected Data Structure. Your file should follow the Request Changes Procedure. If the Data Structure does not exist, select "Request New Data Structure" and upload the appropriate zip file.

Request Submission Exemption
Characters Remaining:
Not Eligible

The Data Expected list for this Collection shows some raw data as missing. Contact the NDA Help Desk with any questions.

Please confirm that you will not be enrolling any more subjects and that all raw data has been collected and submitted.

Collection Updated

Your Collection is now in Data Analysis phase and exempt from biannual submissions. Analyzed data is still expected prior to publication or no later than the project end date.

[CMS] Attention
[CMS] Please confirm that you will not be enrolling any more subjects and that all raw data has been collected and submitted.
[CMS] Error


Unable to change collection phase where targeted enrollment is less than 90%

Delete Submission Exemption
Are you sure you want to delete this submission exemption?
You have requested to move the sharing dates for the following assessments:
Data Expected Item Original Sharing Date New Sharing Date

Please provide a reason for this change, which will be sent to the Program Officers listed within this collection:

Explanation must be between 20 and 200 characters in length.

Please press Save or Cancel
Add New Email Address - Dialog
New Email Address
Collection Summary Collection Charts
Collection Title Collection Investigators Collection Description
Silvio O. Conte Center for Oxytocin and Social Cognition
Larry Young 
The oxytocin (OT) system is arguably the most viable target for pharmacologically enhancing social cognition in psychiatric disorders with compromised social cognition, including autism spectrum disorder (ASD). Central OT enhances key aspects of social behavior in animals, and intranasal (IN) OT modulates social cognition in humans. The mechanisms by which OT affects social cognition are not understood. We will launch a coordinated, interdisciplinary research program involving an outstanding team of investigators to test the hypothesis that OT enhances social cognition by increasing the salience and reinforcing value of social stimuli by modulating activity and functional connectivity of the amygdala and brain regions involved in reward. Project scientists will use cutting edge techniques to assess functional connectivity between brain regions during social interactions, responses of individual neurons in the amygdala to social stimuli, or social cognition in animals and humans. Projects 1 and 2 will use in vivo electrophysiology to examine the impact of OT on the neural representation of social stimuli in rodents and rhesus macaques. Project 3 will use cognitive tests to examine the impact of OT on social perception and social attunement in the primate.Project 4 will use cognitive testing and fMRI to examine the impact of OT on social cognition and neuralactivity in healthy and autistic humans. A Neurochemistry Core will provide vital services for the research projects and develop new tools for characterizing OT receptor expression in the brain. An Administrative Core will coordinate all Center related activities (seminar series, organizing meetings), will provide statistical consultation and coordinate outreach and training activities of Center personnel by strengthening existing relationships and forging new relationships with numerous organizations in the Atlanta area. As a result, the Center will create vibrant collaborative research, training and outreach environment that will have a national impact on mental health research. The data collected by Center faculty will have important transiationaimplications that will directly impact novel strategies for pharmacologically treating social deficits in psychiatric disorders.
NIMH Data Archive
Funding Completed
Close Out
Loading Chart...
NIH - Extramural None

P50MH100023-01 Silvio O. Conte Center for Oxytocin and Social Cognition 07/01/2013 06/30/2018 496 350 EMORY UNIVERSITY $5,908,165.00


NDA Help Center

Collection - General Tab

Fields available for edit on the top portion of the page include:

  • Collection Title
  • Investigators
  • Collection Description
  • Collection Phase
  • Funding Source
  • Clinical Trials

Collection Phase: The current status of a research project submitting data to an NDA Collection, based on the timing of the award and/or the data that have been submitted.

  • Pre-Enrollment: The default entry made when the NDA Collection is created.
  • Enrolling: Data have been submitted to the NDA Collection or the NDA Data Expected initial submission date has been reached for at least one data structure category in the NDA Collection.
  • Data Analysis: Subject level data collection for the research project is completed and has been submitted to the NDA Collection. The NDA Collection owner or the NDA Help Desk may set this phase when they’ve confirmed data submission is complete and submitted subject counts match at least 90% of the target enrollment numbers in the NDA Data Expected. Data submission reminders will be turned off for the NDA Collection.
  • Funding Completed: The NIH grant award (or awards) associated with the NDA Collection has reached its end date. NDA Collections in Funding Completed phase are assigned a subphase to indicate the status of data submission.
    • The Data Expected Subphase indicates that NDA expects more data will be submitted
    • The Closeout Subphase indicates the data submission is complete.
    • The Sharing Not Met Subphase indicates that data submission was not completed as expected.

Blinded Clinical Trial Status:

  • This status is set by a Collection Owner and indicates the research project is a double blinded clinical trial. When selected, the public view of Data Expected will show the Data Expected items and the Submission Dates, but the targeted enrollment and subjects submitted counts will not be displayed.
  • Targeted enrollment and subjects submitted counts are visible only to NDA Administrators and to the NDA Collection or as the NDA Collection Owner.
  • When an NDA Collection that is flagged Blinded Clinical Trial reaches the maximum data sharing date for that Data Repository (see https://nda.nih.gov/nda/sharing-regimen.html), the embargo on Data Expected information is released.

Funding Source

The organization(s) responsible for providing the funding is listed here.

Supporting Documentation

Users with Submission privileges, as well as Collection Owners, Program Officers, and those with Administrator privileges, may upload and attach supporting documentation. By default, supporting documentation is shared to the general public, however, the option is also available to limit this information to qualified researchers only.

Grant Information

Identifiable details are displayed about the Project of which the Collection was derived from. You may click in the Project Number to view a full report of the Project captured by the NIH.

Clinical Trials

Any data that is collected to support or further the research of clinical studies will be available here. Collection Owners and those with Administrator privileges may add new clinical trials.

Frequently Asked Questions

  • How does the NIMH Data Archive (NDA) determine which Permission Group data are submitted into?
    During Collection creation, NDA staff determine the appropriate Permission Group based on the type of data to be submitted, the type of access that will be available to data access users, and the information provided by the Program Officer during grant award.
  • How do I know when a NDA Collection has been created?
    When a Collection is created by NDA staff, an email notification will automatically be sent to the PI(s) of the grant(s) associated with the Collection to notify them.
  • Is a single grant number ever associated with more than one Collection?
    The NDA system does not allow for a single grant to be associated with more than one Collection; therefore, a single grant will not be listed in the Grant Information section of a Collection for more than one Collection.
  • Why is there sometimes more than one grant included in a Collection?
    In general, each Collection is associated with only one grant; however, multiple grants may be associated if the grant has multiple competing segments for the same grant number or if multiple different grants are all working on the same project and it makes sense to hold the data in one Collection (e.g., Cooperative Agreements).


  • Administrator Privilege
    A privilege provided to a user associated with an NDA Collection or NDA Study whereby that user can perform a full range of actions including providing privileges to other users.
  • Collection Owner
    Generally, the Collection Owner is the contact PI listed on a grant. Only one NDA user is listed as the Collection owner. Most automated emails are primarily sent to the Collection Owner.
  • Collection Phase
    The Collection Phase provides information on data submission as opposed to grant/project completion so while the Collection phase and grant/project phase may be closely related they are often different. Collection users with Administrative Privileges are encouraged to edit the Collection Phase. The Program Officer as listed in eRA (for NIH funded grants) may also edit this field. Changes must be saved by clicking the Save button at the bottom of the page. This field is sortable alphabetically in ascending or descending order. Collection Phase options include:
    • Pre-Enrollment: A grant/project has started, but has not yet enrolled subjects.
    • Enrolling: A grant/project has begun enrolling subjects. Data submission is likely ongoing at this point.
    • Data Analysis: A grant/project has completed enrolling subjects and has completed all data submissions.
    • Funding Completed: A grant/project has reached the project end date.
  • Collection Title
    An editable field with the title of the Collection, which is often the title of the grant associated with the Collection.
  • Grant
    Provides the grant number(s) for the grant(s) associated with the Collection. The field is a hyperlink so clicking on the Grant number will direct the user to the grant information in the NIH Research Portfolio Online Reporting Tools (RePORT) page.
  • Supporting Documentation
    Various documents and materials to enable efficient use of the data by investigators unfamiliar with the project and may include the research protocol, questionnaires, and study manuals.
  • NIH Research Initiative
    NDA Collections may be organized by scientific similarity into NIH Research Initiatives, to facilitate query tool user experience. NIH Research Initiatives map to one or multiple Funding Opportunity Announcements.
  • Permission Group
    Access to shared record-level data in NDA is provisioned at the level of a Permission Group. NDA Permission Groups consist of one or multiple NDA Collections that contain data with the same subject consents.
  • Planned Enrollment
    Number of human subject participants to be enrolled in an NIH-funded clinical research study. The data is provided in competing applications and annual progress reports.
  • Actual Enrollment
    Number of human subjects enrolled in an NIH-funded clinical research study. The data is provided in annual progress reports.
  • NDA Collection
    A virtual container and organization structure for data and associated documentation from one grant or one large project/consortium. It contains tools for tracking data submission and allows investigators to define a wide array of other elements that provide context for the data, including all general information regarding the data and source project, experimental parameters used to collect any event-based data contained in the Collection, methods, and other supporting documentation. They also allow investigators to link underlying data to an NDA Study, defining populations and subpopulations specific to research aims.
  • Data Use Limitations
    Data Use Limitations (DULs) describe the appropriate secondary use of a dataset and are based on the original informed consent of a research participant. NDA only accepts consent-based data use limitations defined by the NIH Office of Science Policy.
  • Total Subjects Shared
    The total number of unique subjects for whom data have been shared and are available for users with permission to access data.
IDNameCreated DateStatusType
No records found.

NDA Help Center

Collection - Experiments

The number of Experiments included is displayed in parentheses next to the tab name. You may download all experiments associated with the Collection via the Download button. You may view individual experiments by clicking the Experiment Name and add them to the Filter Cart via the Add to Cart button.

Collection Owners, Program Officers, and users with Submission or Administrative Privileges for the Collection may create or edit an Experiment.

Please note: The creation of an NDA Experiment does not necessarily mean that data collected, according to the defined Experiment, has been submitted or shared.

Frequently Asked Questions

  • Can an Experiment be associated with more than one Collection?

    Yes -see the “Copy” button in the bottom left when viewing an experiment. There are two actions that can be performed via this button:

    1. Copy the experiment with intent for modifications.
    2. Associate the experiment to the collection. No modifications can be made to the experiment.


  • Experiment Status
    An Experiment must be Approved before data using the associated Experiment_ID may be uploaded.
  • Experiment ID
    The ID number automatically generated by NDA which must be included in the appropriate file when uploading data to link the Experiment Definition to the subject record.
Autism Diagnostic Interview, Revised (ADI-R) Clinical Assessments 20
Autism Diagnostic Observation Schedule, 2nd Edition (ADOS-2) - Module 4 Clinical Assessments 12
WASI-2 Clinical Assessments 38
Wechsler Memory Scale, Third Edition (WMS-III) Clinical Assessments 21

NDA Help Center

Collection - Shared Data

This tab provides a quick overview of the Data Structure title, Data Type, and Number of Subjects that are currently Shared for the Collection. The information presented in this tab is automatically generated by NDA and cannot be edited. If no information is visible on this tab, this would indicate the Collection does not have shared data or the data is private.

The shared data is available to other researchers who have permission to access data in the Collection's designated Permission Group(s). Use the Download button to get all shared data from the Collection to the Filter Cart.

Frequently Asked Questions

  • How will I know if another researcher uses data that I shared through the NIMH Data Archive (NDA)?
    To see what data your project have submitted are being used by a study, simply go the Associated Studies tab of your collection. Alternatively, you may review an NDA Study Attribution Report available on the General tab.
  • Can I get a supplement to share data from a completed research project?
    Often it becomes more difficult to organize and format data electronically after the project has been completed and the information needed to create a GUID may not be available; however, you may still contact a program staff member at the appropriate funding institution for more information.
  • Can I get a supplement to share data from a research project that is still ongoing?
    Unlike completed projects where researchers may not have the information needed to create a GUID and/or where the effort needed to organize and format data becomes prohibitive, ongoing projects have more of an opportunity to overcome these challenges. Please contact a program staff member at the appropriate funding institution for more information.


  • Data Structure
    A defined organization and group of Data Elements to represent an electronic definition of a measure, assessment, questionnaire, or collection of data points. Data structures that have been defined in the NDA Data Dictionary are available at https://nda.nih.gov/general-query.html?q=query=data-structure
  • Data Type
    A grouping of data by similar characteristics such as Clinical Assessments, Omics, or Neurosignal data.
  • Shared
    The term 'Shared' generally means available to others; however, there are some slightly different meanings based on what is Shared. A Shared NDA Study is viewable and searchable publicly regardless of the user's role or whether the user has an NDA account. A Shared NDA Study does not necessarily mean that data used in the NDA Study have been shared as this is independently determined. Data are shared according the schedule defined in a Collection's Data Expected Tab and/or in accordance with data sharing expectations in the NDA Data Sharing Terms and Conditions. Additionally, Supporting Documentation uploaded to a Collection may be shared independent of whether data are shared.

Collection Owners and those with Collection Administrator permission, may edit a collection. The following is currently available for Edit on this page:


Publications relevant to NDA data are listed below. Most displayed publications have been associated with the grant within Pubmed. Use the "+ New Publication" button to add new publications. Publications relevant/not relevant to data expected are categorized. Relevant publications are then linked to the underlying data by selecting the Create Study link. Study provides the ability to define cohorts, assign subjects, define outcome measures and lists the study type, data analysis and results. Analyzed data and results are expected in this way.

PubMed IDStudyTitleJournalAuthorsDateStatus
38580810Create StudySocial experience in adolescence shapes prefrontal cortex structure and function in adulthood.Molecular psychiatryLi, Dan C; Hinton, Elizabeth A; Guo, Jidong; Knight, Kristopher A; Sequeira, Michelle K; Wynne, Meghan E; Dighe, Niharika M; Gourley, Shannon LApril 5, 2024Not Determined
38499360Create StudyNeuronal Ensembles in the Amygdala Allow Social Information to Motivate Later Decisions.The Journal of neuroscience : the official journal of the Society for NeuroscienceKietzman, Henry W; Trinoskey-Rice, Gracy; Seo, Esther H; Guo, Jidong; Gourley, Shannon LApril 17, 2024Not Determined
38253222Create StudyMelanocortin agonism in a social context selectively activates nucleus accumbens in an oxytocin-dependent manner.NeuropharmacologyFord, Charles L; McDonough, Anna A; Horie, Kengo; Young, Larry JApril 1, 2024Not Determined
37961356Create StudyNatural variation in oxytocin receptor signaling causes widespread changes in brain transcription: a link to the natural killer gene complex.bioRxiv : the preprint server for biologyBoender, Arjen J; Johnson, Zachary V; Gruenhagen, George W; Horie, Kengo; Hegarty, Brianna E; Streelman, Jeffrey T; Walum, Hasse; Young, Larry JOctober 27, 2023Not Determined
37919790Create StudyIncreased proliferation and neuronal fate in prairie vole brain progenitor cells cultured in vitro: effects by social exposure and sexual dimorphism.Biology of sex differencesÁvila-González, Daniela; Romero-Morales, Italo; Caro, Lizette; Martínez-Juárez, Alejandro; Young, Larry J; Camacho-Barrios, Francisco; Martínez-Alarcón, Omar; Castro, Analía E; Paredes, Raúl G; Díaz, Néstor F; Portillo, WendyNovember 2, 2023Not Determined
37745495Create StudyInstinct to insight: Neural correlates of ethological strategy learning.bioRxiv : the preprint server for biologyLu, Kai; Wong, Kelvin T; Zhou, Lin N; Shi, Yike T; Yang, Chengcheng J; Liu, Robert CSeptember 12, 2023Not Determined
37372130Create StudyThe Neurobiology of Love and Pair Bonding from Human and Animal Perspectives.BiologyBlumenthal, Sarah A; Young, Larry JJune 12, 2023Not Determined
37256960Create StudyAn AAV-CRISPR/Cas9 strategy for gene editing across divergent rodent species: Targeting neural oxytocin receptors as a proof of concept.Science advancesBoender, Arjen J; Boon, Marina; Albers, H Elliott; Eck, Samantha R; Fricker, Brandon A; Kelly, Aubrey M; LeDoux, Joseph E; Motta, Simone C; Shrestha, Prerana; Taylor, Jack H; Trainor, Brian C; Triana-Del Rio, Rodrigo; Young, Larry JJune 2, 2023Not Determined
37188684Create StudyOxytocin receptor antagonism during early vocal learning reduces song preference and imitation in zebra finches.Scientific reportsPilgeram, Natalie R; Baran, Nicole M; Bhise, Aditya; Davis, Matthew T; Iverson, Erik N K; Kim, Emily; Lee, Sumin; Rodriguez-Saltos, Carlos A; Maney, Donna LMay 15, 2023Not Determined
37113978Create StudyDevelopmental pyrethroid exposure causes a neurodevelopmental disorder phenotype in mice.PNAS nexusCurtis, Melissa A; Dhamsania, Rohan K; Branco, Rachel C; Guo, Ji-Dong; Creeden, Justin; Neifer, Kari L; Black, Carlie A; Winokur, Emily J; Andari, Elissar; Dias, Brian G; Liu, Robert C; Gourley, Shannon L; Miller, Gary W; Burkett, James PApril 1, 2023Not Determined
37023360Create StudyReview of Major Social Determinants of Health in Schizophrenia-Spectrum Psychotic Disorders: III. Biology.Schizophrenia bulletinJeste, Dilip V; Malaspina, Dolores; Bagot, Kara; Barch, Deanna M; Cole, Steve; Dickerson, Faith; Dilmore, Amanda; Ford, Charles L; Karcher, Nicole R; Luby, Joan; Rajji, Tarek; Pinto-Tomas, Adrián A; Young, Larry JJuly 4, 2023Not Determined
36762715Create StudyOxytocin antagonist does not disrupt rabbit maternal behavior despite binding to brain oxytocin receptors.Journal of neuroendocrinologyJiménez, Angeles; Jiménez, Pedro; Inoue, Kiyoshi; Young, Larry J; González-Mariscal, GabrielaJuly 1, 2023Not Determined
36736847Create StudyHow social information impacts action in rodents and humans: the role of the prefrontal cortex and its connections.Neuroscience and biobehavioral reviewsKietzman, Henry W; Gourley, Shannon LApril 1, 2023Not Determined
36635470Create StudySong preferences predict the quality of vocal learning in zebra finches.Scientific reportsRodríguez-Saltos, Carlos Antonio; Bhise, Aditya; Karur, Prasanna; Khan, Ramsha Nabihah; Lee, Sumin; Ramsay, Gordon; Maney, Donna LJanuary 12, 2023Not Determined
36271259Create StudyDistribution of vasopressin 1a and oxytocin receptor protein and mRNA in the basal forebrain and midbrain of the spiny mouse (Acomys cahirinus).Brain structure & functionPowell, Jeanne M; Inoue, Kiyoshi; Wallace, Kelly J; Seifert, Ashley W; Young, Larry J; Kelly, Aubrey MMarch 1, 2023Not Determined
36216140Create StudyThe neural basis of smile authenticity judgments and the potential modulatory role of the oxytocin receptor gene (OXTR).Behavioural brain researchLee, Minwoo; Lori, Adriana; Langford, Nicole A; Rilling, James KFebruary 2, 2023Not Determined
36103822Create StudyMedial orbitofrontal neurotrophin systems integrate hippocampal input into outcome-specific value representations.Cell reportsWoon, Ellen P; Butkovich, Laura M; Peluso, Arianna A; Elbasheir, Aziz; Taylor, Kian; Gourley, Shannon LSeptember 13, 2022Not Determined
35970891Create StudySocial incentivization of instrumental choice in mice requires amygdala-prelimbic cortex-nucleus accumbens connectivity.Nature communicationsKietzman, Henry W; Trinoskey-Rice, Gracy; Blumenthal, Sarah A; Guo, Jidong D; Gourley, Shannon LAugust 15, 2022Not Determined
35868206Create StudyEnhanced endogenous oxytocin signaling in the brain modulates neural responses to social misalignment and promotes conformity in humans: A multi-locus genetic profile approach.PsychoneuroendocrinologyLee, Minwoo; Lori, Adriana; Langford, Nicole A; Rilling, James KOctober 1, 2022Not Determined
35863332Create StudyOxytocin, Vasopressin, and Social Behavior: From Neural Circuits to Clinical Opportunities.EndocrinologyRigney, Nicole; de Vries, Geert J; Petrulis, Aras; Young, Larry JSeptember 1, 2022Not Determined
35859012Create StudyThe promise of 3,4-methylenedioxymethamphetamine (MDMA) in combination with prolonged exposure therapy for posttraumatic stress disorder.Neuropsychopharmacology : official publication of the American College of NeuropsychopharmacologyRothbaum, Barbara O; Maples-Keller, Jessica LJanuary 1, 2023Not Determined
35858094Create StudySex-specific and social experience-dependent oxytocin-endocannabinoid interactions in the nucleus accumbens: implications for social behaviour.Philosophical transactions of the Royal Society of London. Series B, Biological sciencesBorie, Amélie M; Young, Larry J; Liu, Robert CAugust 29, 2022Not Determined
35790399Create StudyAge-Induced Changes in µ-Opioid Receptor Signaling in the Midbrain Periaqueductal Gray of Male and Female Rats.The Journal of neuroscience : the official journal of the Society for NeuroscienceFullerton, Evan F; Karom, Mary C; Streicher, John M; Young, Larry J; Murphy, Anne ZAugust 10, 2022Not Determined
35763609Create StudyOxytocin receptors are widely distributed in the prairie vole (Microtus ochrogaster) brain: Relation to social behavior, genetic polymorphisms, and the dopamine system.The Journal of comparative neurologyInoue, Kiyoshi; Ford, Charles L; Horie, Kengo; Young, Larry JNovember 1, 2022Not Determined
35447094Create StudyMarmosets confirm that context is king.NeuronGothard, Katalin MApril 20, 2022Not Determined
35325840Create StudyCell adhesion presence during adolescence controls the architecture of projection-defined prefrontal cortical neurons and reward-related action strategies later in life.Developmental cognitive neuroscienceKietzman, Henry W; Shapiro, Lauren P; Trinoskey-Rice, Gracy; Gourley, Shannon LApril 1, 2022Not Determined
35302856Create StudySaccade-related neural communication in the human medial temporal lobe is modulated by the social relevance of stimuli.Science advancesStaudigl, Tobias; Minxha, Juri; Mamelak, Adam N; Gothard, Katalin M; Rutishauser, UeliMarch 18, 2022Not Determined
35166140Create StudyA randomized controlled trial of 3,4-methylenedioxymethamphetamine (MDMA) and fear extinction retention in healthy adults.Journal of psychopharmacology (Oxford, England)Maples-Keller, Jessica L; Norrholm, Seth D; Burton, Mark; Reiff, Collin; Coghlan, Callan; Jovanovic, Tanja; Yasinski, Carly; Jarboe, Kathleen; Rakofsky, Jeffrey; Rauch, Sheila; Dunlop, Boadie W; Rothbaum, Barbara OMarch 1, 2022Not Determined
35108521Create StudySocial experience alters oxytocinergic modulation in the nucleus accumbens of female prairie voles.Current biology : CBBorie, Amélie M; Agezo, Sena; Lunsford, Parker; Boender, Arjen J; Guo, Ji-Dong; Zhu, Hong; Berman, Gordon J; Young, Larry J; Liu, Robert CMarch 14, 2022Not Determined
35087387Create StudyMaturation of Social-Vocal Communication in Prairie Vole (Microtus ochrogaster) Pups.Frontiers in behavioral neuroscienceWarren, Megan R; Campbell, Drayson; Borie, Amélie M; Ford 4th, Charles L; Dharani, Ammar M; Young, Larry J; Liu, Robert CJanuary 1, 2021Not Determined
35044077Create StudyExploring gene-culture coevolution in humans by inferring neuroendophenotypes: A case study of the oxytocin receptor gene and cultural tightness.Genes, brain, and behaviorLee, Minwoo; Lindo, John; Rilling, James KMarch 1, 2022Not Determined
34880473Create StudyRefining oxytocin therapy for autism: context is key.Nature reviews. NeurologyFord, Charles L; Young, Larry JFebruary 1, 2022Not Determined
34784762Create StudyThe neural correlates of grandmaternal caregiving.Proceedings. Biological sciencesRilling, James K; Gonzalez, Amber; Lee, MinwooNovember 24, 2021Not Determined
34605209Create StudyPostnatal myelination of the immature rat cingulum is regulated by GABAB receptor activity.Developmental neurobiologyPudasaini, Samipa; Friedrich, Vivien; Bührer, Christoph; Endesfelder, Stefanie; Scheuer, Till; Schmitz, ThomasJanuary 1, 2022Not Determined
34562056Create StudyExpression of oxytocin receptors in the zebra finch brain during vocal development.Developmental neurobiologyDavis, Matthew T; Grogan, Kathleen E; Fraccaroli, Isabel; Libecap, Timothy J; Pilgeram, Natalie R; Maney, Donna LJanuary 1, 2022Not Determined
34536549Create StudyDevelopment of a triazolobenzodiazepine-based PET probe for subtype-selective vasopressin 1A receptor imaging.Pharmacological researchHaider, Ahmed; Xiao, Zhiwei; Xia, Xiaotian; Chen, Jiahui; Van, Richard S; Kuang, Shi; Zhao, Chunyu; Rong, Jian; Shao, Tuo; Ramesh, Perla; Aravind, Appu; Shao, Yihan; Ran, Chongzhao; Young, Larry J; Liang, Steven HNovember 1, 2021Not Determined
34482474Create StudyDistribution of brain oxytocin and vasopressin V1a receptors in chimpanzees (Pan troglodytes): comparison with humans and other primate species.Brain structure & functionRogers Flattery, Christina N; Coppeto, Daniel J; Inoue, Kiyoshi; Rilling, James K; Preuss, Todd M; Young, Larry JJune 1, 2022Not Determined
34364786Create StudyHarnessing the healing power of love.Trends in molecular medicineFord, Charles L; Young, Larry JSeptember 1, 2021Not Determined
34271138Create StudyPrioritization of social information by the basolateral amygdala in rats.Neurobiology of learning and memorySong, Zhimin; Swarna, Sujith; Manns, Joseph ROctober 1, 2021Not Determined
34266588Create StudyThe promiscuity of the oxytocin-vasopressin systems and their involvement in autism spectrum disorder.Handbook of clinical neurologyBorie, Amelie M; Theofanopoulou, Constantina; Andari, ElissarJanuary 1, 2021Not Determined
34226275Create StudyParaventricular Nucleus Oxytocin Subsystems Promote Active Paternal Behaviors in Mandarin Voles.The Journal of neuroscience : the official journal of the Society for NeuroscienceHe, Zhixiong; Zhang, Lizi; Hou, Wenjuan; Zhang, Xin; Young, Larry J; Li, Laifu; Liu, Limin; Ma, Huan; Xun, Yufeng; Lv, Zijian; Li, Yitong; Jia, Rui; Li, Jingang; Tai, FadaoAugust 4, 2021Not Determined
34112579Create StudyPersistent behavioral and neurobiological consequences of social isolation during adolescence.Seminars in cell & developmental biologyLi, Dan C; Hinton, Elizabeth A; Gourley, Shannon LOctober 1, 2021Not Determined
34102266Create StudyDistribution of Vasopressin and Oxytocin Neurons in the Basal Forebrain and Midbrain of Spiny Mice (Acomys cahirinus).NeuroscienceKelly, Aubrey M; Seifert, Ashley WAugust 1, 2021Not Determined
34058981Create StudyComparative neurotranscriptomics reveal widespread species differences associated with bonding.BMC genomicsTripp, Joel A; Berrio, Alejandro; McGraw, Lisa A; Matz, Mikhail V; Davis, Jamie K; Inoue, Kiyoshi; Thomas, James W; Young, Larry J; Phelps, Steven MMay 31, 2021Not Determined
34058309Create StudyMicroglia react to partner loss in a sex- and brain site-specific manner in prairie voles.Brain, behavior, and immunityPohl, Tobias T; Jung, Oona; Di Benedetto, Barbara; Young, Larry J; Bosch, Oliver JAugust 1, 2021Not Determined
33864008Create StudyIncerto-thalamic modulation of fear via GABA and dopamine.Neuropsychopharmacology : official publication of the American College of NeuropsychopharmacologyVenkataraman, Archana; Hunter, Sarah C; Dhinojwala, Maria; Ghebrezadik, Diana; Guo, JiDong; Inoue, Kiyoshi; Young, Larry J; Dias, Brian GeorgeAugust 1, 2021Not Determined
33823654Create StudyOxytocin, Neural Plasticity, and Social Behavior.Annual review of neuroscienceFroemke, Robert C; Young, Larry JJuly 8, 2021Not Determined
33775781Create StudyRaised without a father: monoparental care effects over development, sexual behavior, sexual reward, and pair bonding in prairie voles.Behavioural brain researchValera-Marín, Guillermo; Young, Larry J; Camacho, Francisco; Paredes, Raúl G; Rodríguez, Verónica M; Díaz, Néstor F; Portillo, WendyJune 25, 2021Not Determined
33764079Create StudyThe stressed orbitofrontal cortex.Behavioral neuroscienceSequeira, Michelle K; Gourley, Shannon LApril 1, 2021Not Determined
33587397Create StudyEffects of Oxytocin on Emotion Recognition in Schizophrenia: A Randomized Double-Blind Pilot Study.Journal of clinical psychopharmacologyAndari, Elissar; Massa, Nicholas M; Fargotstein, Molly D; Taylor, Nicholas B; Halverson, David M; Owens, Andrew V; Currin, Danielle L; Bhattacharya, Arpita; Gitman, Dmitriy; Cuthbert, Bruce C; Young, Larry J; Duncan, Erica JMarch 1, 2021Not Determined
33582574Create StudyThe role of oxytocin signaling in depression and suicidality in returning war veterans.PsychoneuroendocrinologyWarrener, Corinne D; Valentin, Edward M; Gallin, Camilla; Richey, Lynnet; Ross, Deanna B; Hood, Chelsea J; Lori, Adriana; Cubells, Joseph; Rauch, Sheila A M; Rilling, James KApril 1, 2021Not Determined
33443015Create StudyBrain functional networks associated with social bonding in monogamous voles.eLifeLópez-Gutiérrez, M Fernanda; Gracia-Tabuenca, Zeus; Ortiz, Juan J; Camacho, Francisco J; Young, Larry J; Paredes, Raúl G; Díaz, Néstor F; Portillo, Wendy; Alcauter, SaraelJanuary 14, 2021Not Determined
33260106Create StudyTranslational opportunities for circuit-based social neuroscience: advancing 21st century psychiatry.Current opinion in neurobiologyFord, Charles L; Young, Larry JJune 1, 2021Not Determined
33125871Create StudyOxytocin Influences Male Sexual Activity via Non-synaptic Axonal Release in the Spinal Cord.Current biology : CBOti, Takumi; Satoh, Keita; Uta, Daisuke; Nagafuchi, Junta; Tateishi, Sayaka; Ueda, Ryota; Takanami, Keiko; Young, Larry J; Galione, Antony; Morris, John F; Sakamoto, Tatsuya; Sakamoto, HirotakaJanuary 11, 2021Not Determined
33092784Create StudyInvestigation of Oxtr-expressing Neurons Projecting to Nucleus Accumbens using Oxtr-ires-Cre Knock-in prairie Voles (Microtus ochrogaster).NeuroscienceHorie, Kengo; Inoue, Kiyoshi; Nishimori, Katsuhiko; Young, Larry JNovember 10, 2020Not Determined
32979349Create StudyMethylation of OXT and OXTR genes, central oxytocin, and social behavior in female macaques.Hormones and behaviorDe Leon, Desirée; Nishitani, Shota; Walum, Hasse; McCormack, Kai M; Wilson, Mark E; Smith, Alicia K; Young, Larry J; Sanchez, Mar MNovember 1, 2020Not Determined
32912424Create StudyCumulative Stress Burden on Motivated Action Revealed.Biological psychiatryKietzman, Henry W; Gourley, Shannon LOctober 1, 2020Not Determined
32884100Create StudyGenetic and epigenetic modulation of the oxytocin receptor and implications for autism.Neuropsychopharmacology : official publication of the American College of NeuropsychopharmacologyAndari, Elissar; Rilling, James KJanuary 2021Not Determined
32876047Create StudyMesoscopic-scale functional networks in the primate amygdala.eLifeMorrow, Jeremiah K; Cohen, Michael X; Gothard, Katalin MSeptember 2020Not Determined
32839565Create StudyMultidimensional processing in the amygdala.Nature reviews. NeuroscienceGothard, Katalin MOctober 1, 2020Not Determined
32683141Create StudyOxytocin and postpartum depression: A systematic review.PsychoneuroendocrinologyThul, Taylor A; Corwin, Elizabeth J; Carlson, Nicole S; Brennan, Patricia A; Young, Larry JOctober 1, 2020Not Determined
32556583Create StudyReward-related dynamical coupling between basolateral amygdala and nucleus accumbens.Brain structure & functionHsu, Chia-Chun; Madsen, Teresa E; O'Gorman, Elizabeth; Gourley, Shannon L; Rainnie, Donald GJuly 2020Not Determined
32544402Create StudyOxytocin, vasopressin and social behavior in the age of genome editing: A comparative perspective.Hormones and behaviorBoender, Arjen J; Young, Larry JAugust 1, 2020Not Determined
32502487Create StudyBecoming a better parent: Mice learn sounds that improve a stereotyped maternal behavior.Hormones and behaviorDunlap, Alexander G; Besosa, Cristina; Pascual, Leila M; Chong, Kelly K; Walum, Hasse; Kacsoh, Dorottya B; Tankeu, Brenda B; Lu, Kai; Liu, Robert CAugust 1, 2020Not Determined
32071244Create StudySexually dimorphic role of oxytocin in medaka mate choice.Proceedings of the National Academy of Sciences of the United States of AmericaYokoi S, Naruse K, Kamei Y, Ansai S, Kinoshita M, Mito M, Iwasaki S, Inoue S, Okuyama T, Nakagawa S, Young LJ, Takeuchi HMarch 2020Not Determined
31935400Create StudyOxytocin receptor antagonist reverses the blunting effect of pair bonding on fear learning in monogamous prairie voles.Hormones and behaviorHirota, Yu; Arai, Aki; Young, Larry J; Osako, Yoji; Yuri, Kazunari; Mitsui, ShinichiApril 2020Not Determined
31931508Create StudyEpigenetic modification of the oxytocin receptor gene: implications for autism symptom severity and brain functional connectivity.Neuropsychopharmacology : official publication of the American College of NeuropsychopharmacologyAndari, Elissar; Nishitani, Shota; Kaundinya, Gopinath; Caceres, Gabriella A; Morrier, Michael J; Ousley, Opal; Smith, Alicia K; Cubells, Joseph F; Young, Larry JJune 2020Not Determined
31820488Create StudyInvolvement of the rodent prelimbic and medial orbitofrontal cortices in goal-directed action: A brief review.Journal of neuroscience researchWoon, Ellen P; Sequeira, Michelle K; Barbee, Britton R; Gourley, Shannon LJune 2020Not Determined
31560922Create StudyCircuits for social learning: A unified model and application to Autism Spectrum Disorder.Neuroscience and biobehavioral reviewsDeMayo, Marilena M; Young, Larry J; Hickie, Ian B; Song, Yun Ju C; Guastella, Adam JDecember 2019Not Determined
31533960Create StudyMultidimensional Neural Selectivity in the Primate Amygdala.eNeuroPutnam, Philip T; Gothard, Katalin M2019Not Determined
31527057Create StudySocial Isolation in Adolescence Disrupts Cortical Development and Goal-Dependent Decision-Making in Adulthood, Despite Social Reintegration.eNeuroHinton, Elizabeth A; Li, Dan C; Allen, Aylet G; Gourley, Shannon L2019Not Determined
31509768Create StudyConserved features of anterior cingulate networks support observational learning across species.Neuroscience and biobehavioral reviewsBurgos-Robles, Anthony; Gothard, Katalin M; Monfils, Marie H; Morozov, Alexei; Vicentic, AleksandraDecember 2019Not Determined
31084703Create StudyIncreased anxiety and decreased sociability induced by paternal deprivation involve the PVN-PrL OTergic pathway.eLifeHe Z, Young L, Ma XM, Guo Q, Wang L, Yang Y, Luo L, Yuan W, Li L, Zhang J, Hou W, Qiao H, Jia R, Tai FMay 2019Not Determined
30858163Create StudyMultisensory Neurons in the Primate Amygdala.The Journal of neuroscience : the official journal of the Society for NeuroscienceMorrow J, Mosher C, Gothard KMay 2019Not Determined
30713102Create StudyOxytocin receptor knockout prairie voles generated by CRISPR/Cas9 editing show reduced preference for social novelty and exaggerated repetitive behaviors.Hormones and behaviorHorie, Kengo; Inoue, Kiyoshi; Suzuki, Shingo; Adachi, Saki; Yada, Saori; Hirayama, Takashi; Hidema, Shizu; Young, Larry J; Nishimori, KatsuhikoMay 2019Not Determined
30514927Create StudyEffect of age and autism spectrum disorder on oxytocin receptor density in the human basal forebrain and midbrain.Translational psychiatryFreeman, Sara M; Palumbo, Michelle C; Lawrence, Rebecca H; Smith, Aaron L; Goodman, Mark M; Bales, Karen LDecember 2018Not Determined
30378456Create StudyOxytocin increases eye-gaze towards novel social and non-social stimuli.Social neuroscienceEckstein, Monika; Bamert, Vera; Stephens, Shannon; Wallen, Kim; Young, Larry J; Ehlert, Ulrike; Ditzen, BeateOctober 2019Not Determined
30301953Create StudyThe neural mechanisms and circuitry of the pair bond.Nature reviews. NeuroscienceWalum, Hasse; Young, Larry JNovember 2018Not Determined
30295946Create StudyIntranasal oxytocin in rhesus monkeys alters brain networks that detect social salience and reward.American journal of primatologyParr, Lisa A; Mitchell, Thomas; Hecht, ErinOctober 2018Not Determined
30283367Create StudyThe Role of Amygdala in Patients With Euthymic Bipolar Disorder During Resting State.Frontiers in psychiatryLi, Gaizhi; Liu, Penghong; Andari, Elissar; Zhang, Aixia; Zhang, KerangJanuary 2018Not Determined
30215032Create StudyHeritability of the human connectome: A connectotyping study.Network neuroscience (Cambridge, Mass.)Miranda-Dominguez, Oscar; Feczko, Eric; Grayson, David S; Walum, Hasse; Nigg, Joel T; Fair, Damien AJanuary 2018Not Determined
29923206Create StudyBridging the gap between rodents and humans: The role of non-human primates in oxytocin research.American journal of primatologyPutnam, Philip T; Young, Larry J; Gothard, Katalin MOctober 2018Not Determined
29851879Create StudyMood Disorders.Continuum (Minneapolis, Minn.)Rakofsky J, Rapaport MJune 2018Not Determined
29851228Create StudyEvolutionary diversity as a catalyst for biological discovery.Integrative zoologyJohnson ZV, Young LJMay 2018Not Determined
29842887Create StudyThalamic integration of social stimuli regulating parental behavior and the oxytocin system.Frontiers in neuroendocrinologyDobolyi, Arpad; Cservenák, Melinda; Young, Larry JOctober 2018Not Determined
29797339Create StudyOxytocin- and arginine vasopressin-containing fibers in the cortex of humans, chimpanzees, and rhesus macaques.American journal of primatologyRogers, Christina N; Ross, Amy P; Sahu, Shweta P; Siegel, Ethan R; Dooyema, Jeromy M; Cree, Mary Ann; Stopa, Edward G; Young, Larry J; Rilling, James K; Albers, H Elliott; Preuss, Todd MOctober 2018Not Determined
29660417Create StudyRDoC-based categorization of amygdala functions and its implications in autism.Neuroscience and biobehavioral reviewsHennessey, Thomas; Andari, Elissar; Rainnie, Donald GJuly 2018Not Determined
29352154Create StudyResting state brain networks in the prairie vole.Scientific reportsOrtiz JJ, Portillo W, Paredes RG, Young LJ, Alcauter SJanuary 2018Not Determined
29330007Create StudyLost connections: Oxytocin and the neural, physiological, and behavioral consequences of disrupted relationships.International journal of psychophysiology : official journal of the International Organization of PsychophysiologyPohl, Tobias T; Young, Larry J; Bosch, Oliver JFebruary 2019Not Determined
28875421Create StudyBrief Report: Relationship Between ADOS-2, Module 4 Calibrated Severity Scores (CSS) and Social and Non-Social Standardized Assessment Measures in Adult Males with Autism Spectrum Disorder (ASD).Journal of autism and developmental disordersMorrier, Michael J; Ousley, Opal Y; Caceres-Gamundi, Gabriella A; Segall, Matthew J; Cubells, Joseph F; Young, Larry J; Andari, ElissarDecember 2017Relevant
28872575Create StudyPartner Loss in Monogamous Rodents: Modulation of Pain and Emotional Behavior in Male Prairie Voles.Psychosomatic medicineOsako Y, Nobuhara R, Arai YP, Tanaka K, Young LJ, Nishihara M, Mitsui S, Yuri KSeptember 2017Not Relevant
28812273Create StudyA Precision Medicine Approach to Oxytocin Trials.Current topics in behavioral neurosciencesAndari E, Hurlemann R, Young LJAugust 2017Not Determined
28812266Create StudyOxytocin and Social Relationships: From Attachment to Bond Disruption.Current topics in behavioral neurosciencesBosch OJ, Young LJAugust 2017Not Determined
28800678Create StudyNew perspectives on the neurophysiology of primate amygdala emerging from the study of naturalistic social behaviors.Wiley interdisciplinary reviews. Cognitive scienceGothard KM, Mosher CP, Zimmerman PE, Putnam PT, Morrow JK, Fuglevand AJAugust 2017Not Relevant
28775827Create StudyDevelopmental disruption of amygdala transcriptome and socioemotional behavior in rats exposed to valproic acid prenatally.Molecular autismBarrett CE, Hennessey TM, Gordon KM, Ryan SJ, Mcnair ML, Ressler KJ, Rainnie DGJanuary 2017Not Relevant
28562592Create StudyDynamic corticostriatal activity biases social bonding in monogamous female prairie voles.NatureAmadei, Elizabeth A; Johnson, Zachary V; Jun Kwon, Yong; Shpiner, Aaron C; Saravanan, Varun; Mays, Wittney D; Ryan, Steven J; Walum, Hasse; Rainnie, Donald G; Young, Larry J; Liu, Robert CJune 2017Not Relevant
28460185Create StudyEstablishing Wiring Specificity in Visual System Circuits: From the Retina to the Brain.Annual review of neuroscienceZhang C, Kolodkin AL, Wong RO, James REJuly 2017Not Determined
28434591Create StudyOxytocin and vasopressin neural networks: Implications for social behavioral diversity and translational neuroscience.Neuroscience and biobehavioral reviewsJohnson, Zachary V; Young, Larry JMay 2017Not Relevant
28122239Create StudyFixations Gate Species-Specific Responses to Free Viewing of Faces in the Human and Macaque Amygdala.Cell reportsMinxha J, Mosher C, Morrow JK, Mamelak AN, Adolphs R, Gothard KM, Rutishauser UJanuary 2017Relevant
27922101Create StudySocial determinants of eyeblinks in adult male macaques.Scientific reportsBallesta S, Mosher CP, Szep J, Fischl KD, Gothard KMDecember 2016Not Relevant
27838170Create StudyAn evaluation of central penetration from a peripherally administered oxytocin receptor selective antagonist in nonhuman primates.Bioorganic & medicinal chemistrySmith AL, Walum H, Connor-Stroud F, Freeman SM, Inoue K, Parr LA, Goodman MM, Young LJJanuary 2017Not Relevant
27793769Create StudyOxytocin receptors modulate a social salience neural network in male prairie voles.Hormones and behaviorJohnson ZV, Walum H, Xiao Y, Riefkohl PC, Young LJJanuary 2017Not Relevant
27752543Create StudyTactile Stimulation of the Face and the Production of Facial Expressions Activate Neurons in the Primate Amygdala.eNeuroMosher, Clayton P; Zimmerman, Prisca E; Fuglevand, Andrew J; Gothard, Katalin MSeptember 2016Not Relevant
27522019Create StudyA single prolonged stress paradigm produces enduring impairments in social bonding in monogamous prairie voles.Behavioural brain researchArai A, Hirota Y, Miyase N, Miyata S, Young LJ, Osako Y, Yuri K, Mitsui SDecember 2016Not Relevant
27453637Create StudyDistributions of oxytocin and vasopressin 1a receptors in the Taiwan vole and their role in social monogamy.Journal of zoology (London, England : 1987)Chappell, A R; Freeman, S M; Lin, Y K; LaPrairie, J L; Inoue, K; Young, L J; Hayes, L DJune 2016Not Relevant
27343726Create StudyOxytocin enhances gaze-following responses to videos of natural social behavior in adult male rhesus monkeys.PsychoneuroendocrinologyPutnam, P T; Roman, J M; Zimmerman, P E; Gothard, K MOctober 2016Not Relevant
27209233Create StudyInitial investigation of three selective and potent small molecule oxytocin receptor PET ligands in New World monkeys.Bioorganic & medicinal chemistry lettersSmith AL, Freeman SM, Barnhart TE, Abbott DH, Ahlers EO, Kukis DL, Bales KL, Goodman MM, Young LJJuly 15, 2016Not Relevant
26940141Create StudyComparative Perspectives on Oxytocin and Vasopressin Receptor Research in Rodents and Primates: Translational Implications.Journal of neuroendocrinologyFreeman SM, Young LJApril 2016Not Relevant
26893121Create StudyVariation in the Oxytocin Receptor Gene Predicts Brain Region-Specific Expression and Social Attachment.Biological psychiatryKing LB, Walum H, Inoue K, Eyrich NW, Young LJDecember 15, 2015Not Relevant
26798013Create StudyOxytocin-dependent consolation behavior in rodents.Science (New York, N.Y.)Burkett JP, Andari E, Johnson ZV, Curry DC, de Waal FB, Young LJJanuary 22, 2016Not Relevant
26731103Create StudyThe Macaque Social Responsiveness Scale (mSRS): A Rapid Screening Tool for Assessing Variability in the Social Responsiveness of Rhesus Monkeys (Macaca mulatta).PloS oneFeczko, Eric J; Bliss-Moreau, Eliza; Walum, Hasse; Pruett Jr, John R; Parr, Lisa A2016Not Relevant
26723109Create StudyThe Need for a Theoretical Framework of Social Functioning to Optimize Targeted Therapies in Psychiatric Disorders.Biological psychiatryAndari EFebruary 1, 2016Not Relevant
26723107Create StudyUnderstanding the Oxytocin System and Its Relevance to Psychiatry.Biological psychiatryShamay-Tsoory S, Young LJFebruary 1, 2016Not Relevant
26643557Create StudyCentral oxytocin receptors mediate mating-induced partner preferences and enhance correlated activation across forebrain nuclei in male prairie voles.Hormones and behaviorJohnson ZV, Walum H, Jamal YA, Xiao Y, Keebaugh AC, Inoue K, Young LJMarch 2016Not Relevant
26615473Create StudyOxytocin in the nucleus accumbens shell reverses CRFR2-evoked passive stress-coping after partner loss in monogamous male prairie voles.PsychoneuroendocrinologyBosch OJ, Dabrowska J, Modi ME, Johnson ZV, Keebaugh AC, Barrett CE, Ahern TH, Guo J, Grinevich V, Rainnie DG, Neumann ID, Young LJFebruary 2016Not Relevant
26392632Create StudyEstablishing the reliability of rhesus macaque social network assessment from video observations.Animal behaviourFeczko E, Mitchell TA, Walum H, Brooks JM, Heitz TR, Young LJ, Parr LASeptember 1, 2015Not Determined
26379517Create StudyEditorial: Oxytocin''s routes in social behavior: into the 21st century.Frontiers in behavioral neuroscienceAndari, Elissar2015Not Relevant
26210057Create StudyStatistical and Methodological Considerations for the Interpretation of Intranasal Oxytocin Studies.Biological psychiatryWalum, Hasse; Waldman, Irwin D; Young, Larry JFebruary 1, 2016Not Relevant
26196439Create StudyThe oxytocin system promotes resilience to the effects of neonatal isolation on adult social attachment in female prairie voles.Translational psychiatryBarrett CE, Arambula SE, Young LJ2015Not Relevant
26146650Create StudyNeurobiological mechanisms of social attachment and pair bonding.Current opinion in behavioral sciencesJohnson, Zachary V; Young, Larry JJune 2015Not Relevant
26062432Create StudyNeural mechanisms of mother-infant bonding and pair bonding: Similarities, differences, and broader implications.Hormones and behaviorNuman M, Young LJJanuary 2016Not Relevant
25874849Create StudyRNAi knockdown of oxytocin receptor in the nucleus accumbens inhibits social attachment and parental care in monogamous female prairie voles.Social neuroscienceKeebaugh AC, Barrett CE, Laprairie JL, Jenkins JJ, Young LJ2015Not Relevant
25874677Create StudySensory systems: The yin and yang of cortical oxytocin.NatureLiu, Robert CApril 23, 2015Not Relevant
25700501Create StudyNeuroscience. Can oxytocin treat autism?Science (New York, N.Y.)Young, Larry J; Barrett, Catherine EFebruary 20, 2015Not Relevant
25652247Create StudyMelanocortin Receptor Agonists Facilitate Oxytocin-Dependent Partner Preference Formation in the Prairie Vole.Neuropsychopharmacology : official publication of the American College of NeuropsychopharmacologyModi, Meera E; Inoue, Kiyoshi; Barrett, Catherine E; Kittelberger, Kara A; Smith, Daniel G; Landgraf, Rainer; Young, Larry JJuly 2015Not Relevant
25482173Create StudyOxytocin, social cognition and psychiatry.Neuropsychopharmacology : official publication of the American College of NeuropsychopharmacologyYoung LJJanuary 2015Not Relevant
25414633Create StudySocial relevance drives viewing behavior independent of low-level salience in rhesus macaques.Frontiers in neuroscienceSolyst, James A; Buffalo, Elizabeth A2014Not Relevant
25283782Create StudyNeurons in the monkey amygdala detect eye contact during naturalistic social interactions.Current biology : CBMosher CP, Zimmerman PE, Gothard KMOctober 20, 2014Not Relevant
25124431Create StudyThe biology of mammalian parenting and its effect on offspring social development.Science (New York, N.Y.)Rilling, James K; Young, Larry JAugust 15, 2014Not Relevant
25072016Create StudyAutism Spectrum Disorder: Defining Dimensions and Subgroups.Current developmental disorders reportsOusley, Opal; Cermak, TracyMarch 1, 2014Not Relevant
24845184Create StudyThe neuroanatomical distribution of oxytocin receptor binding and mRNA in the male rhesus macaque (Macaca mulatta).PsychoneuroendocrinologyFreeman SM, Inoue K, Smith AL, Goodman MM, Young LJJuly 2014Not Relevant
24845176Create StudyAerosolized oxytocin increases cerebrospinal fluid oxytocin in rhesus macaques.PsychoneuroendocrinologyModi ME, Connor-Stroud F, Landgraf R, Young LJ, Parr LAJuly 2014Not Relevant
24814726Create StudyNeuroanatomical distribution of oxytocin and vasopressin 1a receptors in the socially monogamous coppery titi monkey (Callicebus cupreus).NeuroscienceFreeman SM, Walum H, Inoue K, Smith AL, Goodman MM, Bales KL, Young LJJuly 25, 2014Not Relevant
24509130Create StudyA nonparametric method for detecting fixations and saccades using cluster analysis: removing the need for arbitrary thresholds.Journal of neuroscience methodsKönig SD, Buffalo EAApril 30, 2014Not Relevant
24367110Create StudyCommon polymorphism in the oxytocin receptor gene (OXTR) is associated with human social recognition skills.Proceedings of the National Academy of Sciences of the United States of AmericaSkuse DH, Lori A, Cubells JF, Lee I, Conneely KN, Puura K, Lehtimäki T, Binder EB, Young LJFebruary 4, 2014Not Determined

NDA Help Center

Collection - Publications

The number of Publications is displayed in parentheses next to the tab name. Clicking on any of the Publication Titles will open the Publication in a new internet browsing tab.

Collection Owners, Program Officers, and users with Submission or Administrative Privileges for the Collection may mark a publication as either Relevant or Not Relevant in the Status column.

Frequently Asked Questions

  • How can I determine if a publication is relevant?
    Publications are considered relevant to a collection when the data shared is directly related to the project or collection.
  • Where does the NDA get the publications?
    PubMed, an online library containing journals, articles, and medical research. Sponsored by NiH and National Library of Medicine (NLM).


  • Create Study
    A link to the Create an NDA Study page that can be clicked to start creating an NDA Study with information such as the title, journal and authors automatically populated.
  • Not Determined Publication
    Indicates that the publication has not yet been reviewed and/or marked as Relevant or Not Relevant so it has not been determined whether an NDA Study is expected.
  • Not Relevant Publication
    A publication that is not based on data related to the aims of the grant/project associated with the Collection or not based on any data such as a review article and, therefore, an NDA Study is not expected to be created.
  • PubMed
    PubMed provides citation information for biomedical and life sciences publications and is managed by the U.S. National Institutes of Health's National Library of Medicine.
  • PubMed ID
    The PUBMed ID is the unique ID number for the publication as recorded in the PubMed database.
  • Relevant Publication
    A publication that is based on data related to the aims of the grant/project associated with the Collection and, therefore, an NDA Study is expected to be created.
Data Expected List: Mandatory Data Structures

These data structures are mandatory for your NDA Collection. Please update the Targeted Enrollment number to accurately represent the number of subjects you expect to submit for the entire study.

For NIMH HIV-related research that involves human research participants: Select the dictionary or dictionaries most appropriate for your research. If your research does not require all three data dictionaries, just ignore the ones you do not need. There is no need to delete extra data dictionaries from your NDA Collection. You can adjust the Targeted Enrollment column in the Data Expected tab to “0” for those unnecessary data dictionaries. At least one of the three data dictionaries must have a non-zero value.

Data ExpectedTargeted EnrollmentInitial SubmissionSubjects SharedStatus
Research Subject and Pedigree info icon
To create your project's Data Expected list, use the "+New Data Expected" to add or request existing structures and to request new Data Structures that are not in the NDA Data Dictionary.

If the Structure you need already exists, locate it and specify your dates and enrollment when adding it to your Data Expected list. If you require changes to the Structure you need, select the indicator stating "No, it requires changes to meet research needs," and upload a file containing your requested changes.

If the structure you need is not yet defined in the Data Dictionary, you can select "Upload Definition" and attach the necessary materials to request its creation.

When selecting the expected dates for your data, make sure to follow the standard Data Sharing Regimen and choose dates within the date ranges that correspond to your project start and end dates.

Please visit the Completing Your Data Expected Tutorial for more information.
Data Expected List: Data Structures per Research Aims

These data structures are specific to your research aims and should list all data structures in which data will be collected and submitted for this NDA Collection. Please update the Targeted Enrollment number to accurately represent the number of subjects you expect to submit for the entire study.

Data ExpectedTargeted EnrollmentInitial SubmissionSubjects SharedStatus
ADOS info icon
ADI-R info icon
Wechsler Abbreviated Scale of Intelligence (WASI) info icon
Autistic Spectrum Quotient info icon
Wechsler Memory Scale, Third Edition (WMS-III) info icon
Structure not yet defined
No Status history for this Data Expected has been recorded yet

NDA Help Center

Collection - Data Expected

The Data Expected tab displays the list of all data that NDA expects to receive in association with the Collection as defined by the contributing researcher, as well as the dates for the expected initial upload of the data, and when it is first expected to be shared, or with the research community. Above the primary table of Data Expected, any publications determined to be relevant to the data within the Collection are also displayed - members of the contributing research group can use these to define NDA Studies, connecting those papers to underlying data in NDA.

The tab is used both as a reference for those accessing shared data, providing information on what is expected and when it will be shared, and as the primary tracking mechanism for contributing projects. It is used by both contributing primary researchers, secondary researchers, and NIH Program and Grants Management staff.

Researchers who are starting their project need to update their Data Expected list to include all the Data Structures they are collecting under their grant and set their initial submission and sharing schedule according to the NDA Data Sharing Regimen.

To add existing Data Structures from the Data Dictionary, to request new Data Structure that are not in the Dictionary, or to request changes to existing Data Structures, click "+New Data Expected".

For step-by-step instructions on how to add existing Data Structures, request changes to an existing Structure, or request a new Data Structure, please visit the Completing Your Data Expected Tutorial.

If you are a contributing researcher creating this list for the first time, or making changes to the list as your project progress, please note the following:

  • Although items you add to the list and changes you make are displayed, they are not committed to the system until you Save the entire page using the "Save" button at the bottom of your screen. Please Save after every change to ensure none of your work is lost.
  • If you attempt to add a new structure, the title you provide must be unique - if another structure exists with the same name your change will fail.
  • Adding a new structure to this list is the only way to request the creation of a new Data Dictionary definition.

Frequently Asked Questions

  • What is an NDA Data Structure?
    An NDA Data Structure is comprised of multiple Data Elements to make up an electronic definition of an assessment, measure, questionnaire, etc will have a corresponding Data Structure.
  • What is the NDA Data Dictionary?
    The NDA Data Dictionary is comprised of electronic definitions known as Data Structures.


  • Analyzed Data
    Data specific to the primary aims of the research being conducted (e.g. outcome measures, other dependent variables, observations, laboratory results, analyzed images, volumetric data, etc.) including processed images.
  • Data Item
    Items listed on the Data Expected list in the Collection which may be an individual and discrete Data Structure, Data Structure Category, or Data Structure Group.
  • Data Structure
    A defined organization and group of Data Elements to represent an electronic definition of a measure, assessment, questionnaire, or collection of data points. Data structures that have been defined in the NDA Data Dictionary are available at https://nda.nih.gov/general-query.html?q=query=data-structure
  • Data Structure Category
    An NDA term describing the affiliation of a Data Structure to a Category, which may be disease/disorder or diagnosis related (Depression, ADHD, Psychosis), specific to data type (MRI, eye tracking, omics), or type of data (physical exam, IQ).
  • Data Structure Group
    A Data Item listed on the Data Expected tab of a Collection that indicates a group of Data Structures (e.g., ADOS or SCID) for which data may be submitted instead of a specific Data Structure identified by version, module, edition, etc. For example, the ADOS Data Structure Category includes every ADOS Data Structure such as ADOS Module 1, ADOS Module 2, ADOS Module 1 - 2nd Edition, etc. The SCID Data Structure Group includes every SCID Data Structure such as SCID Mania, SCID V Mania, SCID PTSD, SCID-V Diagnosis, and more.
  • Evaluated Data
    A new Data Structure category, Evaluated Data is analyzed data resulting from the use of computational pipelines in the Cloud and can be uploaded directly back to a miNDAR database. Evaluated Data is expected to be listed as a Data Item in the Collection's Data Expected Tab.
  • Imaging Data
    Imaging+ is an NDA term which encompasses all imaging related data including, but not limited to, images (DTI, MRI, PET, Structural, Spectroscopy, etc.) as well as neurosignal data (EEG, fMRI, MEG, EGG, eye tracking, etc.) and Evaluated Data.
  • Initial Share Date
    Initial Submission and Initial Share dates should be populated according to the NDA Data Sharing Terms and Conditions. Any modifications to these will go through the approval processes outlined above. Data will be shared with authorized users upon publication (via an NDA Study) or 1-2 years after the grant end date specified on the first Notice of Award, as defined in the applicable Data Sharing Terms and Conditions.
  • Initial Submission Date
    Initial Submission and Initial Share dates should be populated according to these NDA Data Sharing Terms and Conditions. Any modifications to these will go through the approval processes outlined above. Data for all subjects is not expected on the Initial Submission Date and modifications may be made as necessary based on the project's conduct.
  • Research Subject and Pedigree
    An NDA created Data Structure used to convey basic information about the subject such as demographics, pedigree (links family GUIDs), diagnosis/phenotype, and sample location that are critical to allow for easier querying of shared data.
  • Submission Cycle
    The NDA has two Submission Cycles per year - January 15 and July 15.
  • Submission Exemption
    An interface to notify NDA that data may not be submitted during the upcoming/current submission cycle.

Collection Owners and those with Collection Administrator permission, may edit a collection. The following is currently available for Edit on this page:

Associated Studies

Studies that have been defined using data from a Collection are important criteria to determine the value of data shared. The number of subjects column displays the counts from this Collection that are included in a Study, out of the total number of subjects in that study. The Data Use column represents whether or not the study is a primary analysis of the data or a secondary analysis. State indicates whether the study is private or shared with the research community.

Study NameAbstractCollection/Study SubjectsData UsageState
Investigating autism etiology and heterogeneity by decision tree algorithmAutism spectrum disorder (ASD) is a neurodevelopmental disorder that causes deficits in cognition, communication and social skills. ASD, however, is a highly heterogeneous disorder. This heterogeneity has made identifying the etiology of ASD a particularly difficult challenge, as patients exhibit a wide spectrum of symptoms without any unifying genetic or environmental factors to account for the disorder. For better understanding of ASD, it is paramount to identify potential genetic and environmental risk factors that are comorbid with it. Identifying such factors is of great importance to determine potential causes for the disorder, and understand its heterogeneity. Existing large-scale datasets offer an opportunity for computer scientists to undertake this task by utilizing machine learning to reliably and efficiently obtain insight about potential ASD risk factors, which would in turn assist in guiding research in the field. In this study, decision tree algorithms were utilized to analyze related factors in datasets obtained from the National Database for Autism Research (NDAR) consisting of nearly 3000 individuals. We were able to identify 15 medical conditions that were highly associated with ASD diagnoses in patients; furthermore, we extended our analysis to the family medical history of patients and we report six potentially hereditary medical conditions associated with ASD. Associations reported had a 90% accuracy. Meanwhile, gender comparisons highlighted conditions that were unique to each gender and others that overlapped. Those findings were validated by the academic literature, thus opening the way for new directions for the use of decision tree algorithms to further understand the etiology of autism. 12/3382Secondary AnalysisShared
* Data not on individual level

NDA Help Center

Collection - Associated Studies

Clicking on the Study Title will open the study details in a new internet browser tab. The Abstract is available for viewing, providing the background explanation of the study, as provided by the Collection Owner.

Primary v. Secondary Analysis: The Data Usage column will have one of these two choices. An associated study that is listed as being used for Primary Analysis indicates at least some and potentially all of the data used was originally collected by the creator of the NDA Study. Secondary Analysis indicates the Study owner was not involved in the collection of data, and may be used as supporting data.

Private v. Shared State: Studies that remain private indicate the associated study is only available to users who are able to access the collection. A shared study is accessible to the general public.

Frequently Asked Questions

  • How do I associate a study to my collection?
    Studies are associated to the Collection automatically when the data is defined in the Study.


  • Associated Studies Tab
    A tab in a Collection that lists the NDA Studies that have been created using data from that Collection including both Primary and Secondary Analysis NDA Studies.