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Content

Displaying 3 of 3 results

The Osteoarthritis Initiative

https://nda.nih.gov/oai/
oai | NIMH Data Archive - OAI

This repository is under review for potential modification in compliance with Administration directives. The Osteoarthritis Initiative (OAI) is a multi-center, ten-year observational study of men and women, sponsored by the National Institutes of Health (part of the Department of Health and Human Services). The goals of the OAI are to provide resources to enable a better understanding of...

Osteoarthritis Initiative (OAI) Study Protocol

https://nda.nih.gov/oai/study-details/
oai | Osteoarthritis Initiative (OAI) Study Protocol - OAI

This repository is under review for potential modification in compliance with Administration directives. General Inclusion Criteria: Men and women ages 45 79 With, or at risk for, symptomatic femoral-tibial knee OA All ethnic minorities (focus on African-Americans) Major Exclusion Criteria: Inflammatory arthritis (RA) Contraindication to 3T MRI Bilateral end-stage knee OA The Protocol and...

Affecting All Users: Researcher Auth Service (RAS) Login

https://nda.nih.gov/nda/ras-news/
nda | Affecting All Users: Researcher Auth Service (RAS) Login - NDA

This repository is under review for potential modification in compliance with Administration directives. Researcher Auth Service (RAS) is a cloud-based authentication and authorization service that facilitates access to NIHs open and controlled data assets and repositories in a consistent, secure, and user-friendly manner. To reduce the burden on researchers access to NIH data while increasing...

NDA Studies

Displaying 5 of 34 results

Osteoarthritis Initiative (OAI) 72-Month Follow-up Visit (V08)

This study contains the source images collected during the 72-month visit (V08) for the Osteoarthritis Initiative (OAI). The imaging exams performed on all remaining eligible subjects include bilateral PA fixed flexion radiography, as well as right and left knee MRI. The knee trabecular bone MRI acquisitions were obtained in the incidence and non-exposed (control) cohorts as well as those...

Measure (1)
Name Description Primary?
Image Yes

Osteoarthritis Initiative (OAI) 48-Month Follow-up Visit (V06)

This study contains the source images collected during the 48-month visit (V06) for the Osteoarthritis Initiative (OAI). The imaging exams performed on all remaining eligible subjects include bilateral PA fixed knee, bilateral AP standing hip (pelvis) and dominant AP hand radiography as well right knee MRI, left knee MRI and thigh MRI. Some non-exposed (controls) cohort subjects may not have...

Measure (1)
Name Description Primary?
Image Yes

Osteoarthritis Initiative (OAI) 18-Month Follow-Up Visit (V02)

This study contains the source images collected during the 18-month visit (V02) for the Osteoarthritis Initiative (OAI). A subset of progression cohort participants underwent a unilateral knee MRI during this visit.

Measure (1)
Name Description Primary?
Image Yes

Osteoarthritis Initiative (OAI) 48-Month Follow-up Visit (V06)

Clinical data and image analysis data available through the query tool have been updated. If you previously accessed any OAI clinical information or created custom data sets using the query tool, please re-execute your queries with the updated data and download the new packets. https://nda.nih.gov/study.html?id=2506The OAI images have not changed, there is no need to re-download these large ZIP...

Measure (1)
Name Description Primary?
Enrollees Demographics Yes

Osteoarthritis Initiative (OAI) Pre-Screening Visit (P001)

This NDA Study contains all images collected as part of the OAI Pre-Screening visit. The Osteoarthritis Initiative (OAI) is a multi-center, ten-year observational study of men and women, sponsored by the NIH. The goals of the OAI are to provide resources to enable a better understanding of prevention and treatment of knee osteoarthritis, one of the most common causes of disability in adults.

Measure (1)
Name Description Primary?
Enrollees Demographics Yes

Publications

Displaying 5 of 443 results

Association between disease progression and depression onset in persons with radiographic knee osteoarthritis.

Investigators: Rathbun, Alan M; Shardell, Michelle D; Ryan, Alice S; Yau, Michelle S; Gallo, Joseph J; Schuler, Megan S; Stuart, Elizabeth A; Hochberg, Marc C
Appeared in: Rheumatology (Oxford, England) || DOI: 10.1093/rheumatology/keaa141
Grant Number: P50MH115842

OBJECTIVES: Osteoarthritis (OA) disease progression may lead to deteriorating psychosocial function, but it is unclear what aspects of disease severity are related to the onset of depression. This study assessed which components of OA disease progression cumulatively contribute to depression onset in persons with radiographic knee OA. METHODS: Osteoarthritis Initiative participants (n = 1651)...

Collection:
Center to Accelerate Translation of Interventions to Decrease Premature Mortality in SMI
Investigators: Gail Daumit
Shared Subjects: 72
Publication Status: Not Determined

Effects of 12-week aquatic exercise on cardiorespiratory fitness, knee isokinetic function, and Western Ontario and McMaster University osteoarthritis index in patients with knee osteoarthritis women.

Investigators: Ha, Gi-Chul; Yoon, Jae-Ryang; Yoo, Cheol-Gyu; Kang, Seol-Jung; Ko, Kwang-Jun
Appeared in: Journal of exercise rehabilitation || DOI: 10.12965/jer.1836308.154
Grant Number: U54HD090257

The purpose of this study is to investigate the risk factors of metabolic syndrome, cardiorespiratory fitness, knee isokinetic function, and osteoarthritis index inpatients with knee osteoarthritis women. Subjects were divided into the exercise group (n=9, aged 60.89±5.06), and the control groups (n=8, aged 61.25±1.91). Aquatic exercise was performed for 12 weeks, 3 times a week, 60 min a day....

Collection:
District of Columbia Intellectual and Developmental Disabilities Research Center
Investigators: Vittorio Gallo
Shared Subjects: 0
Publication Status: Not Determined

10Kin1day: A Bottom-Up Neuroimaging Initiative.

Investigators: van den Heuvel, Martijn P; Scholtens, Lianne H; van der Burgh, Hannelore K; Agosta, Federica; Alloza, Clara; Arango, Celso; Auyeung, Bonnie; Baron-Cohen, Simon; Basaia, Silvia; Benders, Manon J N L; Beyer, Frauke; Booij, Linda; Braun, Kees P J; Filho, Geraldo Busatto; Cahn, Wiepke; Cannon, Dara M; Chaim-Avancini, Tiffany M; Chan, Sandra S M; Chen, Eric Y H; Crespo-Facorro, Benedicto; Crone, Eveline A; Dannlowski, Udo; de Zwarte, Sonja M C; Dietsche, Bruno; Donohoe, Gary; Plessis, Stefan Du; Durston, Sarah; Díaz-Caneja, Covadonga M; Díaz-Zuluaga, Ana M; Emsley, Robin; Filippi, Massimo; Frodl, Thomas; Gorges, Martin; Graff, Beata; Grotegerd, Dominik; Gąsecki, Dariusz; Hall, Julie M; Holleran, Laurena; Holt, Rosemary; Hopman, Helene J; Jansen, Andreas; Janssen, Joost; Jodzio, Krzysztof; Jäncke, Lutz; Kaleda, Vasiliy G; Kassubek, Jan; Masouleh, Shahrzad Kharabian; Kircher, Tilo; Koevoets, Martijn G J C; Kostic, Vladimir S; Krug, Axel; Lawrie, Stephen M; Lebedeva, Irina S; Lee, Edwin H M; Lett, Tristram A; Lewis, Simon J G; Liem, Franziskus; Lombardo, Michael V; Lopez-Jaramillo, Carlos; Margulies, Daniel S; Markett, Sebastian; Marques, Paulo; Martínez-Zalacaín, Ignacio; McDonald, Colm; McIntosh, Andrew M; McPhilemy, Genevieve; Meinert, Susanne L; Menchón, José M; Montag, Christian; Moreira, Pedro S; Morgado, Pedro; Mothersill, David O; Mérillat, Susan; Müller, Hans-Peter; Nabulsi, Leila; Najt, Pablo; Narkiewicz, Krzysztof; Naumczyk, Patrycja; Oranje, Bob; Ortiz-Garcia de la Foz, Victor; Peper, Jiska S; Pineda, Julian A; Rasser, Paul E; Redlich, Ronny; Repple, Jonathan; Reuter, Martin; Rosa, Pedro G P; Ruigrok, Amber N V; Sabisz, Agnieszka; Schall, Ulrich; Seedat, Soraya; Serpa, Mauricio H; Skouras, Stavros; Soriano-Mas, Carles; Sousa, Nuno; Szurowska, Edyta; Tomyshev, Alexander S; Tordesillas-Gutierrez, Diana; Valk, Sofie L; van den Berg, Leonard H; van Erp, Theo G M; van Haren, Neeltje E M; van Leeuwen, Judith M C; Villringer, Arno; Vinkers, Christiaan H; Vollmar, Christian; Waller, Lea; Walter, Henrik; Whalley, Heather C; Witkowska, Marta; Witte, A Veronica; Zanetti, Marcus V; Zhang, Rui; de Lange, Siemon C
Appeared in: Frontiers in neurology || DOI: 10.3389/fneur.2019.00425
Grant Number: U54MH091657

We organized 10Kin1day, a pop-up scientific event with the goal to bring together neuroimaging groups from around the world to jointly analyze 10,000+ existing MRI connectivity datasets during a 3-day workshop. In this report, we describe the motivation and principles of 10Kin1day, together with a public release of 8,000+ MRI connectome maps of the human brain.

Collection:
HCP-YA Mapping the Human Connectome: Structure, Function, and Heritability
Investigators: David Van Essen
Shared Subjects: 0
Publication Status: Not Determined

Integrative network analysis reveals novel moderators of Aβ-Tau interaction in Alzheimer''s disease.

Investigators: Kitani, Akihiro; Matsui, Yusuke; Alzheimer’s Disease Neuroimaging Initiative
Appeared in: Alzheimer''s research & therapy || DOI: 10.1186/s13195-025-01705-x
Grant Number: UF1AG051197

No Description.

Collection:
Connectomics of Brain Aging and Dementia
Investigators: James Becker
Shared Subjects: 0
Publication Status: Not Determined

Riemannian metric optimization on surfaces (RMOS) for intrinsic brain mapping in the Laplace-Beltrami embedding space.

Investigators: Gahm, Jin Kyu; Shi, Yonggang; Alzheimer’s Disease Neuroimaging Initiative
Appeared in: Medical image analysis || DOI: 10.1016/j.media.2018.03.004
Grant Number: U01EY025864, U01AG051218, U54MH091657

Surface mapping methods play an important role in various brain imaging studies from tracking the maturation of adolescent brains to mapping gray matter atrophy patterns in Alzheimer's disease. Popular surface mapping approaches based on spherical registration, however, have inherent numerical limitations when severe metric distortions are present during the spherical parameterization step. In...

Collections:
HCP-YA Mapping the Human Connectome: Structure, Function, and Heritability
Investigators: David Van Essen
Shared Subjects: 0
Publication Status: Not Determined
The structural and functional connectome across Alzheimers disease subtypes
Investigators: John Ringman
Shared Subjects: 0
Publication Status: Not Determined
Human Connectomes for Low Vision, Blindness, and Sight Restoration
Investigators: Yonggang Shi
Shared Subjects: 0
Publication Status: Not Determined

Collections

Displaying 5 of 111 results

Osteoarthritis Initiative

Investigators: Multiple
Phase:
Grant Number:

The Osteoarthritis Initiative (OAI) is a multi-center, ten-year observational study of men and women, sponsored by the National Institutes of Health (part of the Department of Health and Human Services). The goals of the OAI are to provide a resource to enable a better understanding of prevention and treatment of knee osteoarthritis, one of the most common causes of disability in adults.

Mapping connectomes for disordered emotional states

Investigators: Leanne Williams
Phase:
Grant Number:

Our objective is to use HCP protocols to acquire and make public a large dataset of imaging, behavioral, and symptom data from patients with disordered emotional states. We will also develop and make public new methods for examining how connectome disorganization gives rise to these disordered states at the level of the individual patient. Psychopathology arising from enhanced negative emotion or...

Eating Disorders Genetics Initiative (EDGI)

Investigators: Cynthia Bulik
Phase:
Grant Number:

We propose the Eating Disorders Genetics Initiative EDGI to rapidly and efficiently advance genomic discovery across the three major eating disorders EDs AN anorexia nervosa, BN bulimia nervosa, and BED binge-eating disorder. We propose a testable conceptualization of EDs as arising from a shared genetic vulnerability to a core trait e.g., dysregulated appetite that is further differentiated...

AlphaScenario.com Mental Health Initiative

Investigators: Dean Gladish
Phase:
Grant Number:

N/A

SPIRIT - Suicide Prevention & Implementation Research Initiative

Investigators: Soumitra Pathare
Phase:
Grant Number:

SPIRIT Many suicide prevention interventions have demonstrated efficacy individually, but are not implemented or translated into meaningful care outcomes that can be implemented across multiple contexts. Researching the implementation process is a key to determine whether an integrated intervention is sustainable when implemented on a wider scale. This project aims to close the implementation gap...

Experiments

Displaying 5 of 166 results

Imitate/Observe

Experiment Type: fMRI
Collection (1)

2/3-Social Processes Initiative in Neurobiology of the Schizophrenia(s), Investigators: Anil K Malhotra; Aristotle Voineskos; Robert W. Buchanan

Imitate/Observe

Experiment Type: fMRI
Collection (1)

2/3-Social Processes Initiative in Neurobiology of the Schizophrenia(s), Investigators: Anil K Malhotra; Aristotle Voineskos; Robert W. Buchanan

Empathic Accuracy

Experiment Type: fMRI
Collections (2)

Neuromodulation of Social Cognitive Circuitry in People with Schizophrenia Spectrum Disorders, Investigators: Aristotle Voineskos

2/3-Social Processes Initiative in Neurobiology of the Schizophrenia(s), Investigators: Anil K Malhotra; Aristotle Voineskos; Robert W. Buchanan

Empathic Accuracy

Experiment Type: fMRI
Collections (2)

Neuromodulation of Social Cognitive Circuitry in People with Schizophrenia Spectrum Disorders, Investigators: Aristotle Voineskos

2/3-Social Processes Initiative in Neurobiology of the Schizophrenia(s), Investigators: Anil K Malhotra; Aristotle Voineskos; Robert W. Buchanan

Fear Conditioning Recall

Experiment Type: fMRI
Collection (1)

Acute Neurocognitive-affective Predictors of Chronic Post-trauma Outcomes, Investigators: Christine Larson

936 search results for
The Osteoarthritis Initiative(V06)