NIMH Data Archive - Data

Genomics

Neuroimaging

Phenotype¹

New Trial
Clinical Trial

¹ Numbers reported are subjects by age

New Project
Grant/Project Number

Format should be in the following format: Activity Code, Institute Abbreviation, and Serial Number. Grant Type, Support Year, and Suffix should be excluded. For example, grant 1R01MH123456-01A1 should be entered R01MH123456

Collection - Use Existing Experiment

To associate an experiment to the current collection, just select an axperiment from the table below then click the associate experiment button to persist your changes (saving the collection is not required). Note that once an experiment has been associated to two or more collections, the experiment will not longer be editable.

The table search feature is case insensitive and targets the experiment id, experiment name and experiment type columns. The experiment id is searched only when the search term entered is a number, and filtered using a startsWith comparison. When the search term is not numeric the experiment name is used to filter the results.

Select	Experiment Id	Experiment Name	Experiment Type	Created On

24	HI-NGS_R1	Omics	02/16/2011
475	MB1-10 (CHOP)	Omics	06/07/2016
490	Illumina Infinium PsychArray BeadChip Assay	Omics	07/07/2016
501	PharmacoBOLD Resting State	fMRI	07/27/2016
506	PVPREF	Omics	08/05/2016
509	ABC-CT Resting v2	EEG	08/18/2016
13	Comparison of FI expression in Autistic and Neurotypical Homo Sapiens	Omics	12/28/2010
18	AGRE/Broad Affymetrix 5.0 Genotype Experiment	Omics	01/06/2011
22	Stitching PCR Sequencing	Omics	02/14/2011
26	ASD_Methylation	Omics	03/01/2011
29	Microarray family 03 (father, mother, sibling)	Omics	03/24/2011
37	Standard paired-end sequencing of BCRs	Omics	04/19/2011
38	Illumina Mate-Pair BCR sequencing	Omics	04/19/2011
39	Custom Jumping Libraries	Omics	04/19/2011
40	Custom CapBP	Omics	04/19/2011
41	Immunofluorescence	Omics	05/11/2011
43	Autism brain sample genotyping, Illumina	Omics	05/16/2011
47	ARRA Autism Sequencing Collaboration at Baylor. SOLiD 4 System	Omics	08/01/2011
53	AGRE Omni1-quad	Omics	10/11/2011
59	AGP genotyping	Omics	04/03/2012
60	Ultradeep 454 sequencing of synaptic genes from postmortem cerebella of individuals with ASD and neurotypical controls	Omics	06/23/2012
63	Microemulsion PCR and Targeted Resequencing for Variant Detection in ASD	Omics	07/20/2012
76	Whole Genome Sequencing in Autism Families	Omics	01/03/2013
519	Resting	fMRI	11/08/2016
90	Genotyped IAN Samples	Omics	07/09/2013
91	NJLAGS Axiom Genotyping Array	Omics	07/16/2013
93	AGP genotyping (CNV)	Omics	09/06/2013
106	Longitudinal Sleep Study. H20 200. Channel set 2	EEG	11/07/2013
107	Longitudinal Sleep Study. H20 200. Channel set 3	EEG	11/07/2013
108	Longitudinal Sleep Study. AURA 200	EEG	11/07/2013
105	Longitudinal Sleep Study. H20 200. Channel set 1	EEG	11/07/2013
109	Longitudinal Sleep Study. AURA 400	EEG	11/07/2013
116	Gene Expression Analysis WG-6	Omics	01/07/2014
131	Jeste Lab UCLA ACEii: Charlie Brown and Sesame Street - Project 1	Eye Tracking	02/27/2014
132	Jeste Lab UCLA ACEii: Animacy - Project 1	Eye Tracking	02/27/2014
133	Jeste Lab UCLA ACEii: Mom Stranger - Project 2	Eye Tracking	02/27/2014
134	Jeste Lab UCLA ACEii: Face Emotion - Project 3	Eye Tracking	02/27/2014
145	AGRE/FMR1_Illumina.JHU	Omics	04/14/2014
146	AGRE/MECP2_Sanger.JHU	Omics	04/14/2014
147	AGRE/MECP2_Junior.JHU	Omics	04/14/2014
151	Candidate Gene Identification in familial Autism	Omics	06/09/2014
152	NJLAGS Whole Genome Sequencing	Omics	07/01/2014
154	Math Autism Study - Vinod Menon	fMRI	07/15/2014
155	Resting	fMRI	07/25/2014
156	Speech	fMRI	07/25/2014
159	Emotion	fMRI	07/25/2014
160	syllable contrast	EEG	07/29/2014
167	School-age naturalistic stimuli	Eye Tracking	09/19/2014
44	AGRE/Broad Affymetrix 5.0 Genotype Experiment	Omics	06/27/2011
45	Exome Sequencing of 20 Sporadic Cases of Autism Spectrum Disorder	Omics	07/15/2011

Collection - Add Experiment

Add Supporting Documentation

Funding Source:
URL:

Request Submission Exemption

Not Eligible

The Data Expected list for this Collection shows some raw data as missing. Contact the NDA Help Desk with any questions.

Please confirm that you will not be enrolling any more subjects and that all raw data has been collected and submitted.

Collection Updated

Your Collection is now in Data Analysis phase and exempt from biannual submissions. Analyzed data is still expected prior to publication or no later than the project end date.

[CMS] Error

[CMS]

Unable to change collection phase where targeted enrollment is less than 90%

You have requested to move the sharing dates for the following assessments:

Data Expected Item	Original Sharing Date	New Sharing Date

Please provide a reason for this change, which will be sent to the Program Officers listed within this collection:

Explanation must be between 20 and 200 characters in length.

Please press Save or Cancel

The Social Brain in Schizophrenia and Autism Spectrum Disorders #2022 Collection State:Shared

General
Experiments (47)
Shared Data
Publications (7)
Data Expected (41)
Associated Studies (13)

Collection Title	Collection Investigators	Collection Description
Collection Title:	The Social Brain in Schizophrenia and Autism Spectrum Disorders
Collection Investigators:	Michal Assaf
Collection Description:	Autism measures, diagnostic measures, EEG and fMRI data
Data Repository:	NIMH Data Archive
Permission Group:
Collection Creation Date:	12/05/2012
Collection Phase:	Funding Completed
Collection Sub-Phase:	Close Out
Collection State:	Shared
Blinded Clinical Trial:	No
Total Funded Amount:	$2,555,439.00
Subjects Shared:	159

{"values":[]}

{"values":[["Autism Spectrum Severely Affected",28],["Neurological Control",2],["Typical Control",43],["Not Defined",2],["Autism Spectrum Affected",11]]}

Loading Chart...

Funding Sources:

Funding Source Name	Funding Source URL
NIH - Extramural	None

Supporting Documentation:

Grant Information:

Project Number	Project Title	Start Date	End Date	Planned Enrollment	Actual Enrollment	Organization	Funds Obligated
R01MH095888-01	The Social Brain in Schizophrenia and Autism Spectrum Disorders	07/05/2012	06/30/2018	211	211	HARTFORD HOSPITAL	$2,555,439.00

Clinical Trials:

helpcenter.collection.general-tab

Collection - General Tab

Fields available for edit on the top portion of the page include:

Collection Title
Investigators
Collection Description
Collection Phase
Funding Source
Clinical Trials

Collection Status: The visibility status of an NDA Collection. Collection Status can be Shared or Private. Collections in Shared status are visible to all users and can be searched in the NDA Query Tool. Private Collections are not visible to NDA users. The Status of an NDA Collection only affects the visibility of information about the Collection (metadata) and does not relate to the status of the record-level research data in the NDA Collection.

Collection Phase: The current status of a research project submitting data to an NDA Collection, based on the timing of the award and/or the data that have been submitted.

Pre-Enrollment: The default entry made when the NDA Collection is created.
Enrolling: Data have been submitted to the NDA Collection or the NDA Data Expected initial submission date has been reached for at least one data structure category in the NDA Collection.
Data Analysis: Subject level data collection for the research project is completed and has been submitted to the NDA Collection. The NDA Collection owner or the NDA Help Desk may set this phase when they’ve confirmed data submission is complete and submitted subject counts match at least 90% of the target enrollment numbers in the NDA Data Expected. Data submission reminders will be turned off for the NDA Collection.
Funding Completed: The NIH grant award (or awards) associated with the NDA Collection has reached its end date. NDA Collections in Funding Completed phase are assigned a subphase to indicate the status of data submission.
- The Data Expected Subphase indicates that NDA expects more data will be submitted
- The Closeout Subphase indicates the data submission is complete.
- The Sharing Not Met Subphase indicates that data submission was not completed as expected.

Blinded Clinical Trial Status:

This status is set by a Collection Owner and indicates the research project is a double blinded clinical trial. When selected, the public view of Data Expected will show the Data Expected items and the Submission Dates, but the targeted enrollment and subjects submitted counts will not be displayed.
Targeted enrollment and subjects submitted counts are visible only to NDA Administrators and to the NDA Collection or as the NDA Collection Owner.
When an NDA Collection that is flagged Blinded Clinical Trial reaches the maximum data sharing date for that Data Repository (see https://nda.nih.gov/nda/sharing-regimen.html), the embargo on Data Expected information is released.

Funding Source

The organization(s) responsible for providing the funding is listed here.

Supporting Documentation

Users with Submission privileges, as well as Collection Owners, Program Officers, and those with Administrator privileges, may upload and attach supporting documentation. By default, supporting documentation is shared to the general public, however, the option is also available to limit this information to qualified researchers only.

Grant Information

Identifiable details are displayed about the Project of which the Collection was derived from. You may click in the Project Number to view a full report of the Project captured by the NIH.

Clinical Trials

Any data that is collected to support or further the research of clinical studies will be available here. Collection Owners and those with Administrator privileges may add new clinical trials.

Frequently Asked Questions

How does the NIMH Data Archive (NDA) determine which Permission Group data are submitted into?

During Collection creation, NDA staff determine the appropriate Permission Group based on the type of data to be submitted, the type of access that will be available to data access users, and the information provided by the Program Officer during grant award.
How do I know when a NDA Collection has been created?

When a Collection is created by NDA staff and marked as Shared, an email notification will automatically be sent to the PI(s) of the grant(s) associated with the Collection to notify them.
Is a single grant number ever associated with more than one Collection?

The NDA system does not allow for a single grant to be associated with more than one Collection; therefore, a single grant will not be listed in the Grant Information section of a Collection for more than one Collection.
Why is there sometimes more than one grant included in a Collection?

In general, each Collection is associated with only one grant; however, multiple grants may be associated if the grant has multiple competing segments for the same grant number or if multiple different grants are all working on the same project and it makes sense to hold the data in one Collection (e.g., Cooperative Agreements).

Glossary

Administrator Privilege

A privilege provided to a user associated with an NDA Collection or NDA Study whereby that user can perform a full range of actions including providing privileges to other users.
Collection Owner

Generally, the Collection Owner is the contact PI listed on a grant. Only one NDA user is listed as the Collection owner. Most automated emails are primarily sent to the Collection Owner.
Collection Phase
The Collection Phase provides information on data submission as opposed to grant/project completion so while the Collection phase and grant/project phase may be closely related they are often different. Collection users with Administrative Privileges are encouraged to edit the Collection Phase. The Program Officer as listed in eRA (for NIH funded grants) may also edit this field. Changes must be saved by clicking the Save button at the bottom of the page. This field is sortable alphabetically in ascending or descending order. Collection Phase options include:
- Pre-Enrollment: A grant/project has started, but has not yet enrolled subjects.
- Enrolling: A grant/project has begun enrolling subjects. Data submission is likely ongoing at this point.
- Data Analysis: A grant/project has completed enrolling subjects and has completed all data submissions.
- Funding Completed: A grant/project has reached the project end date.
Collection State

The Collection State indicates whether the Collection is viewable and searchable. Collections can be either Private, Shared, or an Ongoing Study. A Collection that is shared does not necessarily have shared data as the Collection State and state of data are independent of each other. This field can be edited by Collection users with Administrative Privileges and the Program Officer as listed in eRA (for NIH funded grants). Changes must be saved by clicking the Save button at the bottom of the page.
Collection Title

An editable field with the title of the Collection, which is often the title of the grant associated with the Collection.
Grant

Provides the grant number(s) for the grant(s) associated with the Collection. The field is a hyperlink so clicking on the Grant number will direct the user to the grant information in the NIH Research Portfolio Online Reporting Tools (RePORT) page.
Supporting Documentation

Various documents and materials to enable efficient use of the data by investigators unfamiliar with the project and may include the research protocol, questionnaires, and study manuals.
NIH Research Initiative

NDA Collections may be organized by scientific similarity into NIH Research Initiatives, to facilitate query tool user experience. NIH Research Initiatives map to one or multiple Funding Opportunity Announcements.
Permission Group

Access to shared record-level data in NDA is provisioned at the level of a Permission Group. NDA Permission Groups consist of one or multiple NDA Collections that contain data with the same subject consents.
Planned Enrollment

Number of human subject participants to be enrolled in an NIH-funded clinical research study. The data is provided in competing applications and annual progress reports.
Actual Enrollment

Number of human subjects enrolled in an NIH-funded clinical research study. The data is provided in annual progress reports.
NDA Collection

A virtual container and organization structure for data and associated documentation from one grant or one large project/consortium. It contains tools for tracking data submission and allows investigators to define a wide array of other elements that provide context for the data, including all general information regarding the data and source project, experimental parameters used to collect any event-based data contained in the Collection, methods, and other supporting documentation. They also allow investigators to link underlying data to an NDA Study, defining populations and subpopulations specific to research aims.
Data Use Limitations

Data Use Limitations (DULs) describe the appropriate secondary use of a dataset and are based on the original informed consent of a research participant. NDA only accepts consent-based data use limitations defined by the NIH Office of Science Policy.
Total Subjects Shared

The total number of unique subjects for whom data have been shared and are available for users with permission to access data.

Contact NDA Help Desk

ID	Name	Created Date	Status	Type
113	Empathy for physical pain	11/19/2013	Approved	EEG
114	Empathy for Social Pain	11/20/2013	Approved	EEG
115	Control Condition - Objects	11/20/2013	Approved	EEG
209	Domino-NDARVJ555TGV	01/05/2015	Approved	fMRI
215	Domino-NDARXJ280FMM	01/12/2015	Approved	fMRI
216	Domino-NDARAZ912TJD	01/12/2015	Approved	fMRI
217	Domino-NDARKY339NH4	01/12/2015	Approved	fMRI
218	Domino-NDARDU110DKR	01/12/2015	Approved	fMRI
219	Domino-NDARMY489LHC	01/12/2015	Approved	fMRI
220	Domino-NDARJJ992EHJ	01/12/2015	Approved	fMRI
221	Domino-NDARAM139FMF	01/12/2015	Approved	fMRI
222	Domino-NDARPM290LCR	01/12/2015	Approved	fMRI
223	Domino-NDARKF479YWV	01/12/2015	Approved	fMRI
224	Domino-NDARCA181NBN	01/12/2015	Approved	fMRI
225	Domino-NDARDZ103BFY	01/12/2015	Approved	fMRI
226	Domino-NDARUB657KAF	01/12/2015	Approved	fMRI
227	Domino-NDARUU049YGD	01/12/2015	Approved	fMRI
228	Domino-NDARUD984LVB	01/12/2015	Approved	fMRI
229	Domino-NDARWU345VWL	01/12/2015	Approved	fMRI
230	Domino-NDARJF224HU9	01/12/2015	Approved	fMRI
231	Domino-NDARWL686PZR	01/12/2015	Approved	fMRI
232	Domino-NDARTD650ANL	01/12/2015	Approved	fMRI
233	Domino-NDARMA630GXW	01/12/2015	Approved	fMRI
234	Domino-NDARZL464LP3	01/12/2015	Approved	fMRI
235	Domino-NDARFE109KR6	01/12/2015	Approved	fMRI
236	Domino-NDARMR183NJ0	01/12/2015	Approved	fMRI
286	Domino-NDARUR264UC2	04/02/2015	Approved	fMRI
288	Domino-NDARTU546ZAN	04/02/2015	Approved	fMRI
289	Domino-NDARVL456LY3	04/02/2015	Approved	fMRI
290	Domino-NDARKA309TA8	04/02/2015	Approved	fMRI
291	Domino-NDARHA689AFL	04/02/2015	Approved	fMRI
333	Domino-NDARBM216HWV	07/08/2015	Approved	fMRI
334	Domino-NDARMX344LAN	07/08/2015	Approved	fMRI
335	Domino-NDARMX051PLG	07/08/2015	Approved	fMRI
336	Domino-NDARZN300MFA	07/08/2015	Approved	fMRI
337	Domino-NDARHN998PYE	07/08/2015	Approved	fMRI
338	Domino-NDARTP437FA1	07/08/2015	Approved	fMRI
339	Domino-NDARRU826DTU	07/08/2015	Approved	fMRI
340	Domino-NDARWW415NC6	07/08/2015	Approved	fMRI
341	Domino-NDARJB525DPH	07/08/2015	Approved	fMRI
342	Domino-NDARWX815UA3	07/08/2015	Approved	fMRI
343	Domino-NDARAJ114CNZ	07/08/2015	Approved	fMRI
344	Domino-NDAREF482KJ7	07/08/2015	Approved	fMRI
345	Domino-NDARJM920DPY	07/08/2015	Approved	fMRI
346	Domino-NDARRT348FLQ	07/08/2015	Approved	fMRI
442	Domino	02/29/2016	Approved	fMRI
731	Polhemus	07/07/2017	Approved	EEG

helpcenter.collection.experiments-tab

Collection - Experiments

The number of Experiments included is displayed in parentheses next to the tab name. You may download all experiments associated with the Collection via the Download button. You may view individual experiments by clicking the Experiment Name and add them to the Filter Cart via the Add to Cart button.

Collection Owners, Program Officers, and users with Submission or Administrative Privileges for the Collection may create or edit an Experiment.

Please note: The creation of an NDA Experiment does not necessarily mean that data collected, according to the defined Experiment, has been submitted or shared.

Frequently Asked Questions

Can an Experiment be associated with more than one Collection?
Yes -see the “Copy” button in the bottom left when viewing an experiment. There are two actions that can be performed via this button:
1. Copy the experiment with intent for modifications.
2. Associate the experiment to the collection. No modifications can be made to the experiment.

Glossary

Experiment Status

An Experiment must be Approved before data using the associated Experiment_ID may be uploaded.
Experiment ID

The ID number automatically generated by NDA which must be included in the appropriate file when uploading data to link the Experiment Definition to the subject record.

Contact NDA Help Desk

Collection Owners and those with Collection Administrator permission, may edit a collection. The following is currently available for Edit on this page:

Shared Data

Data structures with the number of subjects submitted and shared are provided.

Shared Data:

Title	Type	Number of Subjects
Ambiguous Intentions Hostility Questionnaire	Clinical Assessments	146
Autism Diagnostic Interview, Revised (ADI-R)	Clinical Assessments	17
Autism Diagnostic Observation Schedule (ADOS) - Module 4	Clinical Assessments	25
Autism Diagnostic Observation Schedule, 2nd Edition (ADOS-2) - Module 4	Clinical Assessments	121
Bell Object Relations and Reality Testing Inventory	Clinical Assessments	126
Bell-Lysaker Emotion Recognition Task	Clinical Assessments	146
Bermond-Vorst Alexithymia Scale - Form B	Clinical Assessments	147
Chapman Scales of Psychosis Proneness	Clinical Assessments	150
Current Mood Visual Analogue Scale	Clinical Assessments	116
Demographics	Clinical Assessments	125
Difficulties in Emotion Regulation Scale	Clinical Assessments	148
Domino Post-Scan Debriefing/H-C Version 2	Clinical Assessments	131
Domino Run	Clinical Assessments	110
EEG Subject Experiment	Imaging	4
EEG Subject Files	Imaging	141
Edinburgh Handedness Inventory	Clinical Assessments	150
Empathy Quotient	Clinical Assessments	147
Fagerstrom Test for Nicotine Dependence	Clinical Assessments	131
Heinrich's Quality of Life Scale	Clinical Assessments	122
Hinting Task	Clinical Assessments	149
Hollingshead Socioeconomic Rating Scale	Clinical Assessments	25
Image	Imaging	142
Interpersonal Reactivity Index (IRI)	Clinical Assessments	146
Laterality Test	Clinical Assessments	67
MRI Screening Form	Clinical Assessments	121
Mayer-Salovey-Caruso Emotional Intelligence Test (MSCEIT): Managing Emotions	Clinical Assessments	129
ONRC Health Questionnaire	Clinical Assessments	119
Psychosocial Interview	Clinical Assessments	119
Reading the Mind in the Eyes Task (RMET)	Clinical Assessments	149
Research Subject	Clinical Assessments	48
Rosenberg Self-Esteem Scale	Clinical Assessments	149
Scales for the Assessment of Positive/Negative Symptoms	Clinical Assessments	84
Schizotypal Personality Questionnaire	Clinical Assessments	60
Social Communication Questionnaire (SCQ) - Lifetime	Clinical Assessments	21
Social Functioning Scale	Clinical Assessments	150
Social Responsiveness Scale (SRS) - Adult/Self Version	Clinical Assessments	2
Social Skills Performance Assessment	Clinical Assessments	136
Structured Clinical Interview for DSM-IV	Clinical Assessments	112
Structured Clinical Interview for the Positive and Negative Syndrome Scale	Clinical Assessments	86
The Social Attribution Task-Multiple Choice	Clinical Assessments	150
Wechsler Adult Intelligence Scale III	Clinical Assessments	145
Wechsler Test of Adult Reading	Clinical Assessments	151
Yale Emotion Videos	Clinical Assessments	120
Yale Telephone Screening Form	Clinical Assessments	132

helpcenter.collection.shared-data-tab

Collection - Shared Data

This tab provides a quick overview of the Data Structure title, Data Type, and Number of Subjects that are currently Shared for the Collection. The information presented in this tab is automatically generated by NDA and cannot be edited. If no information is visible on this tab, this would indicate the Collection does not have shared data or the data is private.

The shared data is available to other researchers who have permission to access data in the Collection's designated Permission Group(s). Use the Download button to get all shared data from the Collection to the Filter Cart.

Frequently Asked Questions

How will I know if another researcher uses data that I shared through the NIMH Data Archive (NDA)?

To see what data your project have submitted are being used by a study, simply go the Associated Studies tab of your collection. Alternatively, you may review an NDA Study Attribution Report available on the General tab.
Can I get a supplement to share data from a completed research project?

Often it becomes more difficult to organize and format data electronically after the project has been completed and the information needed to create a GUID may not be available; however, you may still contact a program staff member at the appropriate funding institution for more information.
Can I get a supplement to share data from a research project that is still ongoing?

Unlike completed projects where researchers may not have the information needed to create a GUID and/or where the effort needed to organize and format data becomes prohibitive, ongoing projects have more of an opportunity to overcome these challenges. Please contact a program staff member at the appropriate funding institution for more information.

Glossary

Data Structure

A defined organization and group of Data Elements to represent an electronic definition of a measure, assessment, questionnaire, or collection of data points. Data structures that have been defined in the NDA Data Dictionary are available at https://nda.nih.gov/general-query.html?q=query=data-structure
Data Type

A grouping of data by similar characteristics such as Clinical Assessments, Omics, or Neurosignal data.
Shared

The term 'Shared' generally means available to others; however, there are some slightly different meanings based on what is Shared. A Shared NDA Collection or NDA Study is viewable and searchable publicly regardless of the user's role or whether the user has an NDA account. A Shared Collection or NDA Study does not necessarily mean that data submitted to the Collection or used in the NDA Study have been shared as this is independently determined. Data are shared according the schedule defined in a Collection's Data Expected Tab and/or in accordance with data sharing expectations in the NDA Data Sharing Terms and Conditions. Additionally, Supporting Documentation uploaded to a Collection may be shared independent of whether data are shared, but will only be viewable and accessible if the Collection is Shared.

Contact NDA Help Desk

Collection Owners and those with Collection Administrator permission, may edit a collection. The following is currently available for Edit on this page:

Publications

Publications relevant to NDA data are listed below. Most displayed publications have been associated with the grant within Pubmed. Use the "+ New Publication" button to add new publications. Publications relevant/not relevant to data expected are categorized. Relevant publications are then linked to the underlying data by selecting the Create Study link. Study provides the ability to define cohorts, assign subjects, define outcome measures and lists the study type, data analysis and results. Analyzed data and results are expected in this way.

PubMed ID	Study	Title	Journal	Authors	Date	Status
35766542	Create Study	Factors Related to Passive Social Withdrawal and Active Social Avoidance in Schizophrenia.	The Journal of nervous and mental disease	Farina, Emily A; Assaf, Michal; Corbera, Silvia; Chen, Chi-Ming	July 1, 2022	Not Determined
34875687	Create Study	Atypical Dynamic Functional Network Connectivity State Engagement during Social-Emotional Processing in Schizophrenia and Autism.	Cerebral cortex (New York, N.Y. : 1991)	Hyatt, Christopher J; Wexler, Bruce E; Pittman, Brian; Nicholson, Alycia; Pearlson, Godfrey D; Corbera, Silvia; Bell, Morris D; Pelphrey, Kevin; Calhoun, Vince D; Assaf, Michal	August 3, 2022	Not Determined
34246005	Create Study	Predictors of social functioning and quality of life in schizophrenia and autism spectrum disorder.	Psychiatry research	Corbera, Silvia; Wexler, Bruce E; Bell, Morris D; Pearlson, Godfrey; Mayer, Sophy; Pittman, Brian; Belamkar, Vaishali; Assaf, Michal	September 1, 2021	Not Determined
32711391	Create Study	Default mode network modulation by mentalizing in young adults with autism spectrum disorder or schizophrenia.	NeuroImage. Clinical	Hyatt, Christopher J; Calhoun, Vince D; Pittman, Brian; Corbera, Silvia; Bell, Morris D; Rabany, Liron; Pelphrey, Kevin; Pearlson, Godfrey D; Assaf, Michal	January 2020	Not Determined
31401405	Create Study	Dynamic functional connectivity in schizophrenia and autism spectrum disorder: Convergence, divergence and classification.	NeuroImage. Clinical	Rabany, Liron; Brocke, Sophy; Calhoun, Vince D; Pittman, Brian; Corbera, Silvia; Wexler, Bruce E; Bell, Morris D; Pelphrey, Kevin; Pearlson, Godfrey D; Assaf, Michal	January 2019	Not Determined
29958750	Create Study	Measuring theory of mind in schizophrenia research: Cross-cultural validation.	Schizophrenia research	Lee, Hyeon-Seung; Corbera, Silvia; Poltorak, Ania; Park, Kiho; Assaf, Michal; Bell, Morris D; Wexler, Bruce E; Cho, Young-Il; Jung, Sunho; Brocke, Sophy; Choi, Kee-Hong	November 2018	Not Determined
28291247	Create Study	Enhancing studies of the connectome in autism using the autism brain imaging data exchange II.	Scientific data	Di Martino, Adriana; O'Connor, David; Chen, Bosi; Alaerts, Kaat; Anderson, Jeffrey S; Assaf, Michal; Balsters, Joshua H; Baxter, Leslie; Beggiato, Anita; Bernaerts, Sylvie; Blanken, Laura M E; Bookheimer, Susan Y; Braden, B Blair; Byrge, Lisa; Castellanos, F Xavier; Dapretto, Mirella; Delorme, Richard; Fair, Damien A; Fishman, Inna; Fitzgerald, Jacqueline; Gallagher, Louise; Keehn, R Joanne Jao; Kennedy, Daniel P; Lainhart, Janet E; Luna, Beatriz; Mostofsky, Stewart H; Müller, Ralph-Axel; Nebel, Mary Beth; Nigg, Joel T; O'Hearn, Kirsten; Solomon, Marjorie; Toro, Roberto; Vaidya, Chandan J; Wenderoth, Nicole; White, Tonya; Craddock, R Cameron; Lord, Catherine; Leventhal, Bennett; Milham, Michael P	March 2017	Not Relevant

helpcenter.collection.publications-tab

Collection - Publications

The number of Publications is displayed in parentheses next to the tab name. Clicking on any of the Publication Titles will open the Publication in a new internet browsing tab.

Collection Owners, Program Officers, and users with Submission or Administrative Privileges for the Collection may mark a publication as either Relevant or Not Relevant in the Status column.

Frequently Asked Questions

How can I determine if a publication is relevant?

Publications are considered relevant to a collection when the data shared is directly related to the project or collection.
Where does the NDA get the publications?

PubMed, an online library containing journals, articles, and medical research. Sponsored by NiH and National Library of Medicine (NLM).

Glossary

Create Study

A link to the Create an NDA Study page that can be clicked to start creating an NDA Study with information such as the title, journal and authors automatically populated.
Not Determined Publication

Indicates that the publication has not yet been reviewed and/or marked as Relevant or Not Relevant so it has not been determined whether an NDA Study is expected.
Not Relevant Publication

A publication that is not based on data related to the aims of the grant/project associated with the Collection or not based on any data such as a review article and, therefore, an NDA Study is not expected to be created.
PubMed

PubMed provides citation information for biomedical and life sciences publications and is managed by the U.S. National Institutes of Health's National Library of Medicine.
PubMed ID

The PUBMed ID is the unique ID number for the publication as recorded in the PubMed database.
Relevant Publication

A publication that is based on data related to the aims of the grant/project associated with the Collection and, therefore, an NDA Study is expected to be created.

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Data Expected List: Mandatory Data Structures

These data structures are mandatory for your NDA Collection. Please update the Targeted Enrollment number to accurately represent the number of subjects you expect to submit for the entire study.

Data Expected	Targeted Enrollment	Initial Submission	Subjects Submitted	Initial Share	Subjects Shared	Status
Research Subject and Pedigree	300	07/15/2013	48	11/15/2013	48	Approved

You can use "Add New Data Expected" to add exsiting structures and create your project's list. However, this is also the method you can use to request new structures be created for your project. When adding the Data Expected item, if the structure already exists you can locate it and specify your dates and enrollment. To add a new structure and request it be defined in the Data Dictionary, select Upload Definition and attach the definition or material needed to create it, including manual, codebooks, forms, etc. If you have multiple files, please upload a zipped archive containing them all.

Expected dates should be selected based on the standard Data Sharing Regimen and are restricted to within date ranges based on the project start and end dates.

Data Expected List: Data Structures per Research Aims

These data structures are specific to your research aims and should list all data structures in which data will be collected and submitted for this NDA Collection. Please update the Targeted Enrollment number to accurately represent the number of subjects you expect to submit for the entire study.

Data Expected	Targeted Enrollment	Initial Submission	Subjects Submitted	Initial Share	Subjects Shared	Status
ADOS	300	07/15/2013	145	11/15/2013	145	Approved
ADI-R	300	07/15/2013	17	11/15/2013	17	Approved
Reading the Mind in the Eyes	300	12/27/2017	149	10/30/2018	149	Approved
Medical History	300	07/15/2013	119	11/15/2013	119	Approved
Empathy Quotient (EQ)	300	12/27/2017	147	10/30/2018	147	Approved
Social Responsiveness Scale (SRS)	2	07/15/2013	2	11/15/2013	2	Approved
Interpersonal Reactivity Index	300	12/27/2017	146	10/30/2018	146	Approved
Social Communication Questionnaire (SCQ)	300	07/15/2013	21	11/15/2013	21	Approved
Demographics	300	12/27/2017	149	10/30/2018	149	Approved
Quality of Life Assessment	300	07/15/2013	122	11/15/2013	122	Approved
Structured Clinical Interview for DSM (SCID)	300	07/15/2014	112	11/15/2014	112	Approved
Positive and Negative Syndrome Scale (PANSS)	300	07/15/2014	86	11/15/2014	86	Approved
Scales for the Assessment of Positive/Negative Symptoms	300	07/15/2013	84	11/15/2013	84	Approved
Ambiguous Intentions Hostility Questionnaire	300	07/15/2014	146	11/15/2014	146	Approved
Wechsler Test of Adult Reading	300	12/27/2017	151	10/30/2018	151	Approved
Domino Task	300	12/27/2017	110	10/30/2018	110	Approved
Bell Lysaker Emotion Recognition Test (BLERT)	300	12/27/2017	146	10/30/2018	146	Approved
Hinting Task	300	12/27/2017	149	10/30/2018	149	Approved
Bell Object Relations Reality Testing Inventory (BORRTI)	300	12/27/2017	126	10/30/2018	126	Approved
Social Attribution Task Multiple Choice (SAT-MC)	300	12/27/2017	150	10/30/2018	150	Approved
Bermond-Vorst Alexithymia Questionnaire - B (BVAQ-B)	300	12/27/2017	147	10/30/2018	147	Approved
Social Skills Performance Assessment (SSPA)	300	12/27/2017	136	10/30/2018	136	Approved
Social Functioning Scale (SFS)	300	12/27/2017	150	10/30/2018	150	Approved
Wechsler Adult Intelligence Scale	300	07/15/2013	145	11/15/2013	145	Approved
Physical Exam	300	12/27/2017	150	10/30/2018	150	Approved
Chapman Scales of Psychosis Proneness	300	07/15/2014	150	11/15/2014	150	Approved
Difficulties in Emotion Regulation Scale	300	07/15/2013	148	11/15/2013	148	Approved
Domino Post-Scan Debriefing/H-C Version 2	300	07/15/2014	131	11/15/2014	131	Approved
Laterality Test	300	07/15/2013	67	11/15/2013	67	Approved
Mayer-Salovey-Caruso Emotional Intelligence Test (MSCEIT): Managing Emotions	300	12/27/2017	129	10/30/2018	129	Approved
Rosenberg Self-Esteem Scale	300	07/15/2013	149	11/15/2013	149	Approved
Schizotypal Personality Questionnaire	300	07/15/2013	60	11/15/2013	60	Approved
Yale Emotion Videos	300	07/15/2013	120	11/15/2013	120	Approved
Telephone Screening Form	300	07/15/2013	132	11/15/2013	132	Approved
Current Mood Visual Analogue Scale	300	07/15/2014	116	11/15/2014	116	Approved
Fagerstrom Test for Nicotine Dependence	300	07/15/2014	131	11/15/2014	131	Approved
MRI Screening Form	300	07/15/2014	121	11/15/2014	121	Approved
Imaging (Structural, fMRI, DTI, PET, microscopy)	300	07/15/2014	142	10/30/2018	142	Approved
Psychosocial Interview	300	07/15/2013	119	11/15/2013	119	Approved
EEG	300	12/27/2017	141	10/30/2018	141	Approved

Structure not yet defined

No Status history for this Data Expected has been recorded yet

helpcenter.collection.data-expected-tab

Collection - Data Expected

The Data Expected tab displays the list of all data that NDA expects to receive in association with the Collection as defined by the contributing researcher, as well as the dates for the expected initial upload of the data, and when it is first expected to be shared, or with the research community. Above the primary table of Data Expected, any publications determined to be relevant to the data within the Collection are also displayed - members of the contributing research group can use these to define NDA Studies, connecting those papers to underlying data in NDA.

The tab is used both as a reference for those accessing shared data, providing information on what is expected and when it will be shared, and as the primary tracking mechanism for contributing projects. It is used by both contributing primary researchers, secondary researchers, and NIH Program and Grants Management staff.

Contributing researchers just getting started on their project will need to define this list by adding all of the items they are collecting under their grant and setting their schedule according to the NDA Data Sharing Regimen. If you fall into this category, you can begin by clicking "Add New Data Expected" and selecting which data structures you will be using, saving the page after each change, or requesting new structures by adding and naming a new item, providing any materials NDA Data Dictionary Curators can use to help define your structure. For more information see the tutorial on creating Data Expected.

If you are a contributing researcher creating this list for the first time, or making changes to the list as your project progress, please note the following:

Although items you add to the list and changes you make are displayed, they are not committed to the system until you Save the entire page using the "Save" button at the bottom of your screen. Please Save after every change to ensure none of your work is lost.
If you attempt to add a new structure, the title you provide must be unique - if another structure exists with the same name your change will fail.
Adding a new structure to this list is the only way to request the creation of a new Data Dictionary definition.

Frequently Asked Questions

What is an NDA Data Structure?

An NDA Data Structure is comprised of multiple Data Elements to make up an electronic definition of an assessment, measure, questionnaire, etc will have a corresponding Data Structure.
What is the NDA Data Dictionary?

The NDA Data Dictionary is comprised of electronic definitions known as Data Structures.

Glossary

Analyzed Data

Data specific to the primary aims of the research being conducted (e.g. outcome measures, other dependent variables, observations, laboratory results, analyzed images, volumetric data, etc.) including processed images.
Data Item

Items listed on the Data Expected list in the Collection which may be an individual and discrete Data Structure, Data Structure Category, or Data Structure Group.
Data Structure

A defined organization and group of Data Elements to represent an electronic definition of a measure, assessment, questionnaire, or collection of data points. Data structures that have been defined in the NDA Data Dictionary are available at https://nda.nih.gov/general-query.html?q=query=data-structure
Data Structure Category

An NDA term describing the affiliation of a Data Structure to a Category, which may be disease/disorder or diagnosis related (Depression, ADHD, Psychosis), specific to data type (MRI, eye tracking, omics), or type of data (physical exam, IQ).
Data Structure Group

A Data Item listed on the Data Expected tab of a Collection that indicates a group of Data Structures (e.g., ADOS or SCID) for which data may be submitted instead of a specific Data Structure identified by version, module, edition, etc. For example, the ADOS Data Structure Category includes every ADOS Data Structure such as ADOS Module 1, ADOS Module 2, ADOS Module 1 - 2nd Edition, etc. The SCID Data Structure Group includes every SCID Data Structure such as SCID Mania, SCID V Mania, SCID PTSD, SCID-V Diagnosis, and more.
Evaluated Data

A new Data Structure category, Evaluated Data is analyzed data resulting from the use of computational pipelines in the Cloud and can be uploaded directly back to a miNDAR database. Evaluated Data is expected to be listed as a Data Item in the Collection's Data Expected Tab.
Imaging Data

Imaging+ is an NDA term which encompasses all imaging related data including, but not limited to, images (DTI, MRI, PET, Structural, Spectroscopy, etc.) as well as neurosignal data (EEG, fMRI, MEG, EGG, eye tracking, etc.) and Evaluated Data.
Initial Share Date

Initial Submission and Initial Share dates should be populated according to the NDA Data Sharing Terms and Conditions. Any modifications to these will go through the approval processes outlined above. Data will be shared with authorized users upon publication (via an NDA Study) or 1-2 years after the grant end date specified on the first Notice of Award, as defined in the applicable Data Sharing Terms and Conditions.
Initial Submission Date

Initial Submission and Initial Share dates should be populated according to these NDA Data Sharing Terms and Conditions. Any modifications to these will go through the approval processes outlined above. Data for all subjects is not expected on the Initial Submission Date and modifications may be made as necessary based on the project's conduct.
Research Subject and Pedigree

An NDA created Data Structure used to convey basic information about the subject such as demographics, pedigree (links family GUIDs), diagnosis/phenotype, and sample location that are critical to allow for easier querying of shared data.
Submission Cycle

The NDA has two Submission Cycles per year - January 15 and July 15.
Submission Exemption

An interface to notify NDA that data may not be submitted during the upcoming/current submission cycle.

Contact NDA Help Desk

Collection Owners and those with Collection Administrator permission, may edit a collection. The following is currently available for Edit on this page:

Associated Studies

Studies that have been defined using data from a Collection are important criteria to determine the value of data shared. The number of subjects column displays the counts from this Collection that are included in a Study, out of the total number of subjects in that study. The Data Use column represents whether or not the study is a primary analysis of the data or a secondary analysis. State indicates whether the study is private or shared with the research community.

Study NameFilter by Study Name	AbstractFilter by Abstract	Collection/Study SubjectsFilter by Collection/Study Subjects	Data UsageFilter by Data Usage	StateFilter by State
Controls for SCCRIP	To establish a well characterized cohort for pediatric patients living with sickle cell disease	126/11185	Secondary Analysis	Private
Working Title: Differentiating Core Autism Symptomatology	Autism spectrum disorder (ASD) is characterized by persistent deficits in social communication and social interaction, social-emotional reciprocity, and repetitive behavior or restricted interest (American Psychiatric Association [APA], 2013). This study extends the existing literature by clarifying the extent to which mental health disorder symptoms differentially converge with autism symptoms related to social communication and restricted and repetitive behavior, as well as the extent to which mental health symptoms are empirically differentiated from the core autism symptom domains. Although there is a well-documented correlation between the severity of core ASD symptoms and the presence of mental health disorder symptoms, such as anxiety and irritability, the nature of this linkage remains poorly understood. In this project, the National Database for Autism Research (NDAR) and Research Domain Criteria Database (RDoCdb) were used to observe continuous symptom measures such as the Social Responsiveness Scale (SRS) and the Child Behavior Checklist (CBCL) to examine correlation matrices as well as factor structure models to examine these patterns of association. The SRS “social communication” and “repetitive restricted” subscales were correlated with the CBCL externalizing, internalizing, attention, conduct, aggression, psychosomatic, and withdrawn subscales. We hypothesized that “repetitive and restricted” behaviors would be more correlated with the CBCL scales than would the “social communication” scale. These results were also interpreted according to age and IQ. In conclusion, this study may elucidate ongoing questions about the centrality of mental health symptoms like anxiety to aspects of ASD taxonomy.	2/11144	Secondary Analysis	Private
Characterizing Auditory Hyperreactivity in Autism	Objective: To answer the following research questions: 1) What is the prevalence of auditory hyper-reactivity in ASD? 2) Does auditory hyper-reactivity severity change with age? and 3) What are the most common auditory stimuli reported to be bothersome? Research Design: Primarily descriptive secondary data analysis. Methods: Type of data: Questionnaire items regarding auditory hyper-reactivity will be filtered from: Autism Diagnostic Interview-Revised, Sensory Profile (all forms), Sensory Over-Responsivity Scale, and Sensory Experiences Questionnaire in addition to demographics (i.e., age, race, ethnicity, diagnoses). Analysis Plan: Descriptive statistics, tables and figures will be used to summarize the prevalence and severity of auditory hyper-reactivity by age. Linear regression modeling will be used to evaluate changes in auditory hyper-reactivity by age. If data is available for control subjects, statistical analyses will be conducted for means comparison (ASD vs. non-ASD).	17/7001	Secondary Analysis	Private
The Frequency of Symptom-Based Phenotypes of Mental Disorders is Long-Tailed	The heterogeneity of symptoms among individuals diagnosed with the same mental disorder has been blamed to hinder research in mental health and the development of effective treatments. Although widely acknowledged as problematic, the characteristics of this heterogeneity are largely unknown. We assessed the frequency of symptom phenotypes across a variety of clinical and non-clinical populations and found a consistent, long-tailed distribution. This distribution represents a mixture of a few very commonly expressed phenotypes and the sum of many, each only rarely displayed ones. As a consequence, the non-normality of this distribution induces a systematic bias, affecting all research and treatments relying on a symptom-based definition of mental disorders.	86/5743	Secondary Analysis	Shared
Trajectories of Adult Aging	EEG Trajectories of Aging.	159/3461	Secondary Analysis	Private
Investigating autism etiology and heterogeneity by decision tree algorithm	Autism spectrum disorder (ASD) is a neurodevelopmental disorder that causes deficits in cognition, communication and social skills. ASD, however, is a highly heterogeneous disorder. This heterogeneity has made identifying the etiology of ASD a particularly difficult challenge, as patients exhibit a wide spectrum of symptoms without any unifying genetic or environmental factors to account for the disorder. For better understanding of ASD, it is paramount to identify potential genetic and environmental risk factors that are comorbid with it. Identifying such factors is of great importance to determine potential causes for the disorder, and understand its heterogeneity. Existing large-scale datasets offer an opportunity for computer scientists to undertake this task by utilizing machine learning to reliably and efficiently obtain insight about potential ASD risk factors, which would in turn assist in guiding research in the field. In this study, decision tree algorithms were utilized to analyze related factors in datasets obtained from the National Database for Autism Research (NDAR) consisting of nearly 3000 individuals. We were able to identify 15 medical conditions that were highly associated with ASD diagnoses in patients; furthermore, we extended our analysis to the family medical history of patients and we report six potentially hereditary medical conditions associated with ASD. Associations reported had a 90% accuracy. Meanwhile, gender comparisons highlighted conditions that were unique to each gender and others that overlapped. Those findings were validated by the academic literature, thus opening the way for new directions for the use of decision tree algorithms to further understand the etiology of autism.	121/3382	Secondary Analysis	Shared
Imbalanced social-communicative and restricted repetitive behavior subtypes in autism spectrum disorder exhibit different neural circuitry	Social-communication (SC) and restricted repetitive behaviors (RRB) are autism diagnostic symptom domains. SC and RRB severity can markedly differ within and between individuals and may be underpinned by different neural circuitry and genetic mechanisms. Modeling SC-RRB balance could help identify how neural circuitry and genetic mechanisms map onto such phenotypic heterogeneity. Here, we developed a phenotypic stratification model that makes highly accurate (97–99%) out-of-sample SC = RRB, SC > RRB, and RRB > SC subtype predictions. Applying this model to resting state fMRI data from the EU-AIMS LEAP dataset (n = 509), we find that while the phenotypic subtypes share many commonalities in terms of intrinsic functional connectivity, they also show replicable differences within some networks compared to a typically-developing group (TD). Specifically, the somatomotor network is hypoconnected with perisylvian circuitry in SC > RRB and visual association circuitry in SC = RRB. The SC = RRB subtype show hyperconnectivity between medial motor and anterior salience circuitry. Genes that are highly expressed within these networks show a differential enrichment pattern with known autism-associated genes, indicating that such circuits are affected by differing autism-associated genomic mechanisms. These results suggest that SC-RRB imbalance subtypes share many commonalities, but also express subtle differences in functional neural circuitry and the genomic underpinnings behind such circuitry.	1/1708	Secondary Analysis	Shared
Investigating possible biomarkers of autism in resting EEG	There are no clinically useful biomarkers of autism spectrum disorder (ASD). Electroencephalogram (EEG) can measure ongoing brain dynamics using cheap and widely available technology and is minimally invasive. As such, any measurement drived from EEG that is capable of serving as a biomarker for ASD would be hugely beneficial. Previous research has been conflicting and a large list of EEG measures have been suggested.	12/771	Secondary Analysis	Shared
Development of EEG dynamics throughout the lifespan	Combining data from across several datasets available on the NIMH data repository, multiple metrics of EEG dynamics were examined in a large cross sectional sample of healthy participants from across the lifespan. The goal was to examine changes in brain dynamics that occur across development.	39/551	Secondary Analysis	Shared
Face-processing performance is an independent predictor of social affect as measured by the Autism Diagnostic Observation Schedule across large-scale datasets	Face-processing deficits, while not required for the diagnosis of Autism Spectrum Disorder (ASD), have been associated with impaired social skills—a core feature of ASD; however, the strength and prevalence of this relationship remains unclear. Across 445 participants from the NIMH Data Archive, we examined the relationship between Benton Face Recognition Test (BFRT) performance and Autism Diagnostic Observation Schedule-Social Affect (ADOS-SA) scores. Lower BFRT scores (worse face-processing performance) were associated with higher ADOS-SA scores (higher ASD severity)–a relationship that held after controlling for other factors associated with face processing, i.e., age, sex, and IQ. These findings underscore the utility of face discrimination, not just recognition of facial emotion, as a key covariate for the severity of symptoms that characterize ASD.	1/445	Secondary Analysis	Shared
comparing EEG metrics during eyes closed versus eyes open rest in autism	Understanding the complex relationship between brain dynamics and mental disorders has proved difficult. Sample sizes have often been small, and brain dynamics have often been evaluated in only one state. Here, data obtained from the NIMH data archive were used to create a sample of 395 individuals with both eyes open and eyes closed resting state EEG data. All data were submitted to a standard pipeline to extract power spectra, peak alpha frequency, the slope of the 1/f curve, multi scale sample entropy, phase amplitude coupling, and intersite phase clustering. These data along with the survey data collected at the time of data collection form a valuable resource for interogating the relationship between brain state changes and autism diagnosis.	1/336	Secondary Analysis	Shared
Aging trajectories in adults with ASD.	Autism spectrum disorder (ASD) is a neurodevelopmental condition characterized by lifelong social communication impairments (American Psychiatric Association. 2013). The CDC estimates that 5.4 million adults in the U.S. currently have an ASD (Dietz et al. 2020), and that one in four of these adults will be over 65 years by 2035 (Bureau n.d.). Several lines of evidence demonstrate that individuals with ASD are more vulnerable to age-related health risks (Hand et al. 2020), including cognitive decline (Lever and Geurts 2016; Powell et al. 2017). Recent studies also show that neurophysiological brain aging markers decline atypically in adults with ASD (Koolschijn et al. 2017; Walsh et al. 2019). Here we examine if slowing of oscillatory brain activity, a key sign of neural aging, occurs at a faster rate in ASD compared to NT controls. Oscillatory slowing will be quantified using the peak frequency of alpha oscillations (7-13Hz). Peak alpha frequency will be extracted from the resting EEG data of adults with an ASD diagnosis, and age-matched controls. Associations between peak alpha frequency and age will be assessed and compared between groups.	157/269	Secondary Analysis	Private
Measuring theory of mind in schizophrenia research: Cross-cultural validation.	Theory of mind (ToM) is the ability to understand mental states of others and it is crucial for building sensitivity to other persons or events. Measuring ToM is important for understanding and rehabilitating social cognitive impairments in persons with schizophrenia. The Social Attribution Task-Multiple Choice (SAT-MC) has been successfully employed to measure ToM between individuals with schizophrenia (SZ) and healthy controls (HC) in North America. Given that the SAT-MC uses geometric shapes, is nonverbal and less culturally loaded than other social cognition measures, it may serve for measuring ToM in schizophrenia across cultures. A total of 120 participants (30 per group; Korean SZ; Korean HC; North American SZ; North American HC) were selected from existing databases to examine the reliability and validity of the SAT-MC. Internal consistency, factor structure, measurement invariance, discriminant validity, and convergent/divergent validity were examined. The SAT-MC had good internal consistency regardless of the clinical and cultural group as evidence by Cronbach's α ≥ 0.78 in all groups. Confirmatory factor analysis confirmed the one-factor model with a good model fit (χ2 = 188.122, TLI = 0.958, CFI = 0.963, RMSEA = 0.045). The SAT-MC was sensitive to detect individual differences in ToM of SZ and HC, regardless of culture (p < 0.001), and significantly correlated with other social cognition tasks (Hinting and Reading the Mind in the Eyes Test) among Korean and North American patients. The SAT-MC is a reliable measure for evaluating ToM in both Koreans and North Americans with or without schizophrenia, supporting its potential utility in diverse language and cultures for schizophrenia research.	36/36	Secondary Analysis	Shared

* Data not on individual level

helpcenter.collection.associated-studies-tab

Collection - Associated Studies

Clicking on the Study Title will open the study details in a new internet browser tab. The Abstract is available for viewing, providing the background explanation of the study, as provided by the Collection Owner.

Primary v. Secondary Analysis: The Data Usage column will have one of these two choices. An associated study that is listed as being used for Primary Analysis indicates at least some and potentially all of the data used was originally collected by the creator of the NDA Study. Secondary Analysis indicates the Study owner was not involved in the collection of data, and may be used as supporting data.

Private v. Shared State: Studies that remain private indicate the associated study is only available to users who are able to access the collection. A shared study is accessible to the general public.

Frequently Asked Questions

How do I associate a study to my collection?

Studies are associated to the Collection automatically when the data is defined in the Study.

Glossary

Associated Studies Tab

A tab in a Collection that lists the NDA Studies that have been created using data from that Collection including both Primary and Secondary Analysis NDA Studies.

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