NDA Help Center

Collection - General Tab

Fields available for edit on the top portion of the page include:

  • Collection Title
  • Investigators
  • Collection Description
  • Collection Phase
  • Funding Source
  • Clinical Trials

Collection Status: The visibility status of an NDA Collection.  Collection Status can be Shared or Private.  Collections in Shared status are visible to all users and can be searched in the NDA Query Tool. Private Collections are not visible to NDA users.  The Status of an NDA Collection only affects the visibility of information about the Collection (metadata) and does not relate to the status of the record-level research data in the NDA Collection.

Collection Phase: The current status of a research project submitting data to an NDA Collection, based on the timing of the award and/or the data that have been submitted.
 

  • Pre-Enrollment: The default entry made when the NDA Collection is created.
     
  • Enrolling: Data have been submitted to the NDA Collection or the NDA Data Expected initial submission date has been reached for at least one data structure category in the NDA Collection.
     
  • Data Analysis: Subject level data collection for the research project is completed and has been submitted to the NDA Collection.  The NDA Collection owner or the NDA Help Desk may set this phase when they’ve confirmed data submission is complete and submitted subject counts match at least 90% of the target enrollment numbers in the NDA Data Expected. Data submission reminders will be turned off for the NDA Collection.
     
  • Funding Completed: The NIH grant award (or awards) associated with the NDA Collection has reached its end date. NDA Collections in Funding Completed phase are assigned a subphase to indicate the status of data submission.
     
    • The Data Expected Subphase indicates that NDA expects more data will be submitted
    • The Closeout Subphase indicates the data submission is complete.
    • The Sharing Not Met Subphase indicates that data submission was not completed as expected. 

Blinded Clinical Trial Status:

  • This status is set by a Collection Owner and indicates the research project is a double blinded clinical trial.  When selected, the public view of Data Expected will show the Data Expected items and the Submission Dates, but the targeted enrollment and subjects submitted counts will not be displayed.
     
  • Targeted enrollment and subjects submitted counts are visible only to NDA Administrators and to the NDA Collection or as the NDA Collection Owner.
     
  • When an NDA Collection that is flagged Blinded Clinical Trial reaches the maximum data sharing date for that Data Repository (see https://nda.nih.gov/about/sharing-regimen.html), the embargo on Data Expected information is released.
     

Funding Source

The organization(s) responsible for providing the funding is listed here. 

Supporting Documentation

Users with Submission privileges, as well as Collection Owners, Program  Officers, and those with Administrator privileges, may upload and attach supporting documentation. By default, supporting documentation is shared to the general public, however, the option is also available to limit this information to qualified researchers only. 

Grant Information 

Identifiable details are displayed about the Project of which the Collection was derived from. You may click in the Project Number to view a full report of the Project captured by the NIH. 

Clinical Trials

Any data that is collected to support or further the research of clinical studies will be available here. Collection Owners and those with Administrator privileges may add new clinical trials. 

Frequently Asked Questions

  • When a Collection is created by NDA staff and marked as Shared, an email notification will automatically be sent to the PI(s) of the grant(s) associated with the Collection to notify them.

  • During Collection creation, NDA staff determine the appropriate Permission Group based on the type of data to be submitted, the type of access that will be available to data access users, and the information provided by the Program Officer during grant award.

  • The NDA system does not allow for a single grant to be associated with more than one Collection; therefore, a single grant will not be listed in the Grant Information section of a Collection for more than one Collection.

  • In general, each Collection is associated with only one grant; however, multiple grants may be associated if the grant has multiple competing segments for the same grant number or if multiple different grants are all working on the same project and it makes sense to hold the data in one Collection (e.g., Cooperative Agreements).

Glossary

  • Number of human subjects enrolled in an NIH-funded clinical research study. The data is provided in annual progress reports.

  • A privilege provided to a user associated with an NDA Collection or NDA Study whereby that user can perform a full range of actions including providing privileges to other users. 

  • Generally, the Collection Owner is the contact PI listed on a grant. Only one NDA user is listed as the Collection owner. Most automated emails are primarily sent to the Collection Owner.

  • The Collection Phase provides information on data submission as opposed to grant/project completion so while the Collection phase and grant/project phase may be closely related they are often different.  Collection users with Administrative Privileges are encouraged to edit the Collection Phase.  The Program Officer as listed in eRA (for NIH funded grants) may also edit this field. Changes must be saved by clicking the Save button at the bottom of the page.  This field is sortable alphabetically in ascending or descending order. Collection Phase options include: 

    • Pre-Enrollment:  A grant/project has started, but has not yet enrolled subjects.
    • Enrolling:  A grant/project has begun enrolling subjects.  Data submission is likely ongoing at this point.
    • Data Analysis:  A grant/project has completed enrolling subjects and has completed all data submissions.
    • Funding Completed:  A grant/project has reached the project end date.
  • The Collection State indicates whether the Collection is viewable and searchable.  Collections can be either Private, Shared, or an Ongoing Study.  A Collection that is shared does not necessarily have shared data as the Collection State and state of data are independent of each other.  This field can be edited by Collection users with Administrative Privileges and the Program Officer as listed in eRA (for NIH funded grants). Changes must be saved by clicking the Save button at the bottom of the page.

  • An editable field with the title of the Collection, which is often the title of the grant associated with the Collection.

  • Data Use Limitations (DULs) describe the appropriate secondary use of a dataset and are based on the original informed consent of a research participant. NDA only accepts consent-based data use limitations defined by the NIH Office of Science Policy.

  • Provides the grant number(s) for the grant(s) associated with the Collection.  The field is a hyperlink so clicking on the Grant number will direct the user to the grant information in the NIH Research Portfolio Online Reporting Tools (RePORT) page.

  • A virtual container and organization structure for data and associated documentation from one grant or one large project/consortium. It contains tools for tracking data submission and allows investigators to define a wide array of other elements that provide context for the data, including all general information regarding the data and source project, experimental parameters used to collect any event-based data contained in the Collection, methods, and other supporting documentation. They also allow investigators to link underlying data to an NDA Study, defining populations and subpopulations specific to research aims. 

  • NDA Collections may be organized by scientific similarity into NIH Research Initiatives, to facilitate query tool user experience. NIH Research Initiatives map to one or multiple Funding Opportunity Announcements. 

  • Access to shared record-level data in NDA is provisioned at the level of a Permission Group. NDA Permission Groups consist of one or multiple NDA Collections that contain data with the same subject consents.

  • Number of human subject participants to be enrolled in an NIH-funded clinical research study. The data is provided in competing applications and annual progress reports.

  • Various documents and materials to enable efficient use of the data by investigators unfamiliar with the project and may include the research protocol, questionnaires, and study manuals.  

  • The total number of unique subjects for whom data have been shared and are available for users with permission to access data.

NDA Help Center

Collection - Shared Data Tab

This tab provides a quick overview of the Data Structure title, Data Type, and Number of Subjects that are currently Shared for the Collection. The information presented in this tab is automatically generated by NDA and cannot be edited. If no information is visible on this tab, this would indicate the Collection does not have shared data or the data is private.

The shared data is available to other researchers who have permission to access data in the Collection's designated Permission Group(s). Use the Download button to get all shared data from the Collection to the Filter Cart.

 

Frequently Asked Questions

  • To see what data your project have submitted are being used by a study, simply go the Associated Studies tab of your collection.  Alternatively, you may review an NDA Study Attribution Report available on the General tab.  

  • Often it becomes more difficult to organize and format data electronically after the project has been completed and the information needed to create a GUID may not be available; however, you may still contact a program staff member at the appropriate funding institution for more information.

  • Unlike completed projects where researchers may not have the information needed to create a GUID and/or where the effort needed to organize and format data becomes prohibitive, ongoing projects have more of an opportunity to overcome these challenges.  Please contact a program staff member at the appropriate funding institution for more information.

Glossary

  • A defined organization and group of Data Elements to represent an electronic definition of a measure, assessment, questionnaire, or collection of data points.  Data structures that have been defined in the NDA Data Dictionary are available at https://ndar.nih.gov/data_dictionary.html. 

  • A grouping of data by similar characteristics such as Clinical Assessments, Omics, or Neurosignal data.

  • The term 'Shared' generally means available to others; however, there are some slightly different meanings based on what is Shared.  A Shared NDA Collection or NDA Study is viewable and searchable publicly regardless of the user's role or whether the user has an NDA account.  A Shared Collection or NDA Study does not necessarily mean that data submitted to the Collection or used in the NDA Study have been shared as this is independently determined.  Data are shared according the schedule defined in a Collection's Data Expected Tab and/or in accordance with data sharing expectations in the NDA Data Sharing Terms and Conditions.  Additionally, Supporting Documentation uploaded to a Collection may be shared independent of whether data are shared, but will only be viewable and accessible if the Collection is Shared.

NDA Help Center

fMRi

fMRI stands for functional magnetic resonance imaging. fMRI tests measure blood flow, providing detailed functional images of the brain or body. 

Acquisition
The Acquisition parameters needed for an experiment include the following:

The name of the experiment is required. Please be concise and specific as possible.
Following experiment name, selection boxes are provided for the Equipment, Software, or other items specific to the experiment type. At least one selection is required for each. If NDAR does not have the appropriate listing, select Add New to add the information provided. Following the selection boxes, provide additional information may be required depending on the experiment type. Any required items are denoted by an asterisk (*).

Block/Event Design
At least one block/event is required. Note that any fields denoted with an asterisk (*) are required. All data must be devoid of personally identifiable data, including the contents of any files attached to the experiment.

Note: To simplify the definition of multiple events, we provide an Import from XML function. This function supports importing data from all three experiment sections (Acquisition, Block/Event Design, and Post Processing), at this time files cannot be uploaded from XML A test format is provided here and our XML Schema Definition (xsd) can be found here.

Post Processing
If you have completed any post-processing on your data, please choose 'Yes' for Has Postprocessing? If not, select 'No'. Depending on this selection the remaining post-processing fields will be enabled (some of which will be required). If you are initially providing data you can select 'No', then return to the experiment to add post-processing steps at a later date when the data are being provided.

Please provide information about post-processing manipulations, i.e. artifact detection algorithms, segmentation used for post data collection, items denoted with an asterisk (*) are required.

Frequently Asked Questions

Glossary

  • This button will add all selections to the Filter Cart. 

  • This button will allow you to copy all of the Experiment details as a template for a new experiment. 

  • Adds all data from the current selections in a Collection or NDA Study to the Filter Cart.

  • This button will allow you to return to the Experiments tab. 

NDA Help Center

Collection - Submissions Tab

Users with permission to access Shared data in the Collection’s assigned Permission Group may use this tab. 

Here, you can:

  • Review your uploads to your Collection, monitor their status, and download them individually to verify their contents.
  • Download individual datasets as a secondary user of the data approved for access.
  • Identify and download datasets containing errors identified by NDA's QA/QC process for review and resolution.
  • Report suspected or discovered Personally Identifiable Information in a submission via the Actions column.

Frequently Asked Questions

Glossary

  • The default view of Datasets within a Collection's Submission tab.

  • A Submission Loading Status on a Collection's Submission Tab that indicates that an issue has prevented the successful loading of the submission.  Users should contact the NDA Help Desk for assistance at NDAHelp@mail.nih.gov.

  • The NDA has two Submission Cycles per year - January 15 and July 15.

  • An interface to notify NDA that data may not be submitted during the upcoming/current submission cycle.  

  • The unique and sequentially assigned ID for a submission (e.g. a discrete upload via the Validation and Upload Tool), which may contain any number of datafiles, Data Structures and/or Data Types, regardless of the Submission Loading Status. A single submission may be divided into multiple Datasets, which are based on Data Type.

  • The total number of unique subjects for whom data have been shared and are available for users with permission to access data.

  • The total number of unique subjects for whom data have been submitted, which includes data in both a Private State and a Shared State.

NDA Help Center

Collection - Publications Tab

The number of Publications is displayed in parentheses next to the tab name. Clicking on any of the Publication Titles will open the Publication in a new internet browsing tab. 

Collection Owners, Program Officers, and users with Submission or Administrative Privileges for the Collection may mark a publication as either Relevant or Not Relevant in the Status column. 

 

Frequently Asked Questions

  • Publications are considered relevant to a collection when the data shared is directly related to the project or collection.

  • PubMed, an online library containing journals, articles, and medical research. Sponsored by NiH and National Library of Medicine (NLM). 

Glossary

  • A link to the Create an NDA Study page that can be clicked to start creating an NDA Study with information such as the title, journal and authors automatically populated.

  • Indicates that the publication has not yet been reviewed and/or marked as Relevant or Not Relevant so it has not been determined whether an NDA Study is expected.

  • A publication that is not based on data related to the aims of the grant/project associated with the Collection or not based on any data such as a review article and, therefore, an NDA Study is not expected to be created.

  • PubMed provides citation information for biomedical and life sciences publications and is managed by the U.S. National Institutes of Health's National Library of Medicine.

  • The PUBMed ID is the unique ID number for the publication as recorded in the PubMed database.  

  • A publication that is based on data related to the aims of the grant/project associated with the Collection and, therefore, an NDA Study is expected to be created.

NDA Help Center

EEG

EEG stands for electroencencephalogram and is a test used to measure electrical activity in the brain.

Acquisition
The Acquisition parameters needed for an experiment include the following:

Name of the experiment is required. Please be concise and specific as possible.
Following experiment name, selection boxes are provided for the Equipment, Software, or other items specific to experiment type. At least one selection is required for each. If NDAR does not have the appropriate listing, select Add New to add the information provided. Following the selection boxes, provide additional information may be required depending on experiment type. Any required items are denoted by an asterisk (*).

Block/Event Design
At least one block/event is required. Note that any fields denoted with an asterisk (*) are required. All data must be devoid of personally identifiable data, including the contents of any files attached to the experiment.

Note: To simplify definition of multiple events, we provide an Import from XML function. This function supports importing data from all three experiment sections (Acquisition, Block/Event Design, and Post Processing), at this time files cannot be uploaded from XML A test format is provided here and our XML Schema Definition (xsd) can be found here.

Post Processing
If you have completed any post processing on your data, please choose 'Yes' for Has Postprocessing? If not, select 'No'. Depending on this selection the remaining post processing fields will be enabled (some of which will be required). If you are initially providing data you can select 'No', then return to the experiment to add post processing steps at a later date when the data are being provided.

Please provide information about post-processing manipulations, i.e. artifact detection algorithms, segmentation used for post data collection, items denoted with an asterisk (*) are required.

Frequently Asked Questions

Glossary

  • This button will add all selections to the Filter Cart. 

  • This button will allow you to copy all of the Experiment details as a template for a new experiment. 

  • Adds all data from the current selections in a Collection or NDA Study to the Filter Cart.

  • This button will allow you to return to the Experiments tab. 

NDA Help Center

Collection - Data Expected

The Data Expected tab displays the list of all data that NDA expects to receive in association with the Collection as defined by the contributing researcher, as well as the dates for the expected initial upload of the data, and when it is first expected to be shared, or with the research community. Above the primary table of Data Expected, any publications determined to be relevant to the data within the Collection are also displayed - members of the contributing research group can use these to define NDA Studies, connecting those papers to underlying data in NDA.

The tab is used both as a reference for those accessing shared data, providing information on what is expected and when it will be shared, and as the primary tracking mechanism for contributing projects. It is used by both contributing primary researchers, secondary researchers, and NIH Program and Grants Management staff.

Contributing researchers just getting started on their project will need to define this list by adding all of the items they are collecting under their grant and setting their schedule according to the NDA Data Sharing Regimen. If you fall into this category, you can begin by clicking "add new Data Expected" and selecting which data structures you will be using, saving the page after each change, or requesting new structures by adding and naming a new item, providing any materials NDA Data Dictionary Curators can use to help define your structure. For more information see the tutorial on creating Data Expected.

If you are a contributing researcher creating this list for the first time, or making changes to the list as your project progress, please note the following:

  • Although items you add to the list and changes you make are displayed, they are not committed to the system until you Save the entire page using the "Save" button at the bottom of your screen. Please Save after every change to ensure none of your work is lost.
  • If you attempt to add a new structure, the title you provide must be unique - if another structure exists with the same name your change will fail.
  • Adding a new structure to this list is the only way to request the creation of a new Data Dictionary definition.

 

Frequently Asked Questions

  • An NDA Data Structure is comprised of multiple Data Elements to make up an electronic definition of an assessment, measure, questionnaire, etc will have a corresponding Data Structure.

  • The NDA Data Dictionary is comprised of electronic definitions known as Data Structures.

Glossary

  • Data specific to the primary aims of the research being conducted (e.g. outcome measures, other dependent variables, observations, laboratory results, analyzed images, volumetric data, etc.) including processed images.

  • Items listed on the Data Expected list in the Collection which may be an individual and discrete Data Structure, Data Structure Category, or Data Structure Group.

  • A defined organization and group of Data Elements to represent an electronic definition of a measure, assessment, questionnaire, or collection of data points.  Data structures that have been defined in the NDA Data Dictionary are available at https://ndar.nih.gov/data_dictionary.html. 

  • An NDA term describing the affiliation of a Data Structure to a Category, which may be disease/disorder or diagnosis related (Depression, ADHD, Psychosis), specific to data type (MRI, eye tracking, omics), or type of data (physical exam, IQ).

  • A Data Item listed on the Data Expected tab of a Collection that indicates a group of Data Structures (e.g., ADOS or SCID) for which data may be submitted instead of a specific Data Structure identified by version, module, edition, etc. For example, the ADOS Data Structure Category includes every ADOS Data Structure such as ADOS Module 1, ADOS Module 2, ADOS Module 1 - 2nd Edition, etc. The SCID Data Structure Group includes every SCID Data Structure such as SCID Mania, SCID V Mania, SCID PTSD, SCID-V Diagnosis, and more. 

  • A new Data Structure category, Evaluated Data is analyzed data resulting from the use of computational pipelines in the Cloud and can be uploaded directly back to a miNDAR database.  Evaluated Data is expected to be listed as a Data Item in the Collection's Data Expected Tab.

  • Imaging+ is an NDA term which encompasses all imaging related data including, but not limited to, images (DTI, MRI, PET, Structural, Spectroscopy, etc.) as well as neurosignal data (EEG, fMRI, MEG, EGG, eye tracking, etc.) and Evaluated Data.

  • Initial Submission and Initial Share dates should be populated according to the NDA Data Sharing Terms and Conditions. Any modifications to these will go through the approval processes outlined above. Data will be shared with authorized users upon publication (via an NDA Study) or 1-2 years after the grant end date specified on the first Notice of Award, as defined in the applicable Data Sharing Terms and Conditions.

  • Initial Submission and Initial Share dates should be populated according to these NDA Data Sharing Terms and Conditions. Any modifications to these will go through the approval processes outlined above. Data for all subjects is not expected on the Initial Submission Date and modifications may be made as necessary based on the project's conduct.

  • An NDA created Data Structure used to convey basic information about the subject such as demographics, pedigree (links family GUIDs), diagnosis/phenotype, and sample location that are critical to allow for easier querying of shared data.

  • The NDA has two Submission Cycles per year - January 15 and July 15.

  • An interface to notify NDA that data may not be submitted during the upcoming/current submission cycle.  

NDA Help Center

Collection - Permissions Tab

Collection Owners, Program Officers, and users with Administrator privileges may view this tab.

The available permission groups include:

  • Query: This read-only access is generally for NIH Program Officers
  • Submission: This will grant read access and allow the user to upload data and create experiment definitions. This is for the typical contributing personnel member.
  • Administrator: In addition to the access provided to Query and Submission users, Admins can also edit the Collection itself, create or edit the Data Expected list, and edit user permissions. This access is for the PI, data managers, and anyone they wish to delegate this to.

The PI has a special designation as the Collection Owner in addition to administrator access.

Frequently Asked Questions

  • Collection Owners and Admins may assign Collection Privileges to anyone.

  • Yes, you can assign various Privileges to other users with an NDA account.

  • If you are the Collection Owner or have Admin privileges, you can view and make changes to the list of individuals who have access to the Collection on the Collection's Permissions tab.  Information on users who have access to data Shared in your Collection because they were granted access to a Permission Group is not available.

  • Staff/collaborators who are working submitting data to the Collection, checking the quality of the data, and/or analyzing data should have access for the duration of the project until all data have been submitted, NDA Studies have been created for data used in publications, and/or a collaborative relationship with the user exists.  

  • The individual listed as an Investigator on the General tab of the NDA Collection will generally be able to provide a user access to the NDA Collection.  Additional users may also have this ability if granted Administrator access to an NDA Collection; however, these users are not viewable unless your account has access to the NDA Collection.  Given this, it is best to contact the Investigator to request access to the Collection.

  • Privileges that can be assigned to a user include:
    Submission allows a user to submit data to Collection
    Query allows the user to download data from Collection even when in a Private state
    Admin is both the Submission and Query Privilege + the ability to give privileges to other users.

  • You may have staff who are working on the submission of data or other activities associated with data sharing such as the definition of the Data Expected list or NDA Experiment creation.  Also, many projects have multiple performance sites and wish to share data among the site PIs.  Submitting to the NDA facilitates access by all investigators working on a project even before data have been shared with other users.  You can control who gets access to data while in a Private state.

Glossary

  • A privilege provided to a user associated with an NDA Collection or NDA Study whereby that user can perform a full range of actions including providing privileges to other users. 

  • Access to shared record-level data in NDA is provisioned at the level of a Permission Group. NDA Permission Groups consist of one or multiple NDA Collections that contain data with the same subject consents.

NDA Help Center

Eye Tracking

EyeTracking tests follow the movement of the eye. The visual trajectory or focus can help determine predictions and assist in diagnoses. 

Acquisition
The Acquisition parameters needed for an experiment include the following:

The name of the experiment is required. Please be concise and specific as possible.
Following experiment name, selection boxes are provided for the Equipment, Software, or other items specific to the experiment type. At least one selection is required for each. If NDAR does not have the appropriate listing, select Add New to add the information provided. Following the selection boxes, provide additional information may be required depending on the experiment type. Any required items are denoted by an asterisk (*).

Block/Event Design
At least one block/event is required. Note that any fields denoted with an asterisk (*) are required. All data must be devoid of personally identifiable data, including the contents of any files attached to the experiment.

Note: To simplify the definition of multiple events, we provide an Import from XML function. This function supports importing data from all three experiment sections (Acquisition, Block/Event Design, and Post Processing), at this time files cannot be uploaded from XML A test format is provided here and our XML Schema Definition (xsd) can be found here.

Post Processing
If you have completed any post-processing on your data, please choose 'Yes' for Has Postprocessing? If not, select 'No'. Depending on this selection the remaining post-processing fields will be enabled (some of which will be required). If you are initially providing data you can select 'No', then return to the experiment to add post-processing steps at a later date when the data are being provided.

Please provide information about post-processing manipulations, i.e. artifact detection algorithms, segmentation used for post data collection, items denoted with an asterisk (*) are required.

Frequently Asked Questions

Glossary

  • This button will add all selections to the Filter Cart. 

  • This button will allow you to copy all of the Experiment details as a template for a new experiment. 

  • Adds all data from the current selections in a Collection or NDA Study to the Filter Cart.

  • This button will allow you to return to the Experiments tab. 

NDA Help Center

Collection - Experiments Tab

The number of Experiments included is displayed in parentheses next to the tab name. You may download all experiments associated with the Collection via the Download button. You may view individual experiments by clicking the Experiment Name and add them to the Filter Cart via the Add to Cart button.

Collection Owners, Program Officers, and users with Submission or Administrative Privileges for the Collection may create or edit an Experiment.

Please note: The creation of an NDA Experiment does not necessarily mean that data collected, according to the defined Experiment, has been submitted or shared.

Frequently Asked Questions

  • Yes -see the “Copy” button in the bottom left when viewing an experiment. There are two actions that can be performed via this button:

    1. Copy the experiment with intent for modifications.  
    2. Associate the experiment to the collection. No modifications can be made to the experiment.

     

Glossary

  • An Experiment must be Approved before data using the associated Experiment_ID may be uploaded.

  • The ID number automatically generated by NDA which must be included in the appropriate file when uploading data to link the Experiment Definition to the subject record.

NDA Help Center

Omics

Omics is a collective group of technologies, related to a field of study in Biology such as Genomics or proteomics. 

Experiment Parameters

To define an Omics experiment, provide a meaningful name and select a single molecule. The standard molecules are listed. However, if you are doing proteomic or environmental experiments, simply “Add New” and the new selection will be created. Only one value for molecule is permitted.

Next the technology (box 2) associated with the molecule will be presented along with its application. Again, only one selection is possible. If you wish to see all of NDAR’s options for any one box, Select “Show All”.

Platform

Continue to select the Platform (box 3).

Extraction

Next, the Extraction Protocol (box 4) and Kits (box 5) are presented based upon the Molecule selected and the Processing Protocol (box 6) and Kits (box 7) are presented based upon the Molecule and Technology Application (Box 1 and 2)

Processing

Note that for each of these (boxes 4, 5, 6, and 7) multiple selections are possible.

Additional Information

Lastly, the Software (box 8) and Equipment (box 9) is expected.

 

Once saved, the experiment will be associated with the Collection and by using the returned Experiment_ID, the NDA makes it possible to associate the experiment meta data directly with the data from the experiment.

Frequently Asked Questions

Glossary

  • This button will add all selections to the Filter Cart. 

  • This button will allow you to copy all of the Experiment details as a template for a new experiment. 

  • Adds all data from the current selections in a Collection or NDA Study to the Filter Cart.

  • This button will allow you to return to the Experiments tab. 

NDA Help Center

Filter Cart

Viewable at the top right of NDA pages, the Filter Cart is a temporary holder for filters and data they select. Filters are added to the Workspace first, before being submitted to The Filter Cart. Data selected by filters in the Filter Cart can be added to a Data Package or an NDA Study from the Data Packaging Page, by clicking the 'Create Data Package / Add Data to Study' button.

The filter cart supports combining multiple filters together, and depending on filter type will use "AND" or "OR"  when combining filters.

Multiple selections from the same filter type will result in those selections being applied with an ‘OR’ condition. For example, if you add an NDA Collection Filter with selections for both collections 2112 and 2563 to an empty Workspace, the subjects from NDA Collection 2112 ‘OR’ NDA Collection 2563 will be added to your Workspace even if a subject is in both NDA Collections. You can then add other NDA Collections to your Workspace which further extends the ‘OR’ condition.

If a different filter type is added to your Workspace, or a filter has already been submitted to the Filter Cart, the operation then performs a logical ‘AND’ operation. This means that given the subjects returned from the first filter, only those subjects that matched the first filter are returned by the second filter (i.e., subjects that satisfied both filters).

When combining other filters with the GUID filter, please note the GUID filter should be added last. Otherwise, preselected data may be lost. For example, a predefined filter from Featured Datasets may select a subset of data available for a subject. When combined with a GUID filter for the same subject, the filter cart will contain all data available from that subject, data structure, and dataset; this may be more data than was selected in the predefined filter for that subject. Again, you should add the GUID Filter as the last filter to your cart. This ensures 'AND' logic between filters and will limit results to the subjects, data structures, and datasets already included in your filter cart.

Note that only the subjects specific to your filter will be added to your Filter Cart and only on data shared with the research community. Other data for those same subjects may exist (i.e., within another NDA Collection, associated with a data structure that was not requested in the query, etc.). So, users should select ‘Find all Subjects Data’ to identify all data for those specific subjects. 

Additional Tips:

  • You may query the data without an account, but to gain access you will need to create an NDA user account and apply for access.  Most data access requires that you or your lab are sponsored by an NIH recognized institution with Federal Wide Assurance (FWA).  Without access, you will not be able to obtain individual-level data. 

    Once you have selected data of interest you can:
  • Create a data package - This allows you to specify format for access/download
  • Assign to Study Cohort - Associate the data to an NDA Study allowing for a DOI to be generated and the data to be linked directly to a finding, publication, or data release. 
  • Find All Subject Data - Depending on filter types being used, not all data associated with a subject will be selected.  Data may be restricted by data structure, NDA Collection, or outcome variables (e.g., NDA Study). ‘Find All Data’ expands the fliter criteria by replacing all filters in your Filter Cart with a single Query by GUID filter for all subjects selected by those filters.

    Please Note:
  • When running a query, it may take a moment to populate the Filter Cart. Queries happen in the background so you can define other queries during this time. 
  • When you add your first filter, all data associated with your query will be added to the Filter Cart (e.g., a Concept, an NDA Collection, a Data Structure/Element, etc.). As you add additional filters, they will also display in the Filter Cart. Only the name of filter will be shown in the Filter Cart, not the underlying structures. 
  • Information about the contents of the Filter Cart can be seen by clicking "Edit”.
  • Once your results appear in the Filter Cart, you can create a data package or assign subjects to a study by selecting the 'Package/Assign to Study' option. You can also 'Edit' or 'Clear' filters.
     

Frequently Asked Questions

  • The Filter Cart currently employs basic AND/OR Boolean logic. A single filter may contain multiple selections for that filter type, e.g., a single NDA Study filter might contain NDA Study 1 and NDA Study 2. A subject that is in EITHER 1 OR 2 will be returned.  Adding multiple filters to the cart, regardless of type, will AND the result of each filter.  If NDA Study 1 and NDA Study 2 are added as individual filters, data for a subject will only be selected if the subject is included in  BOTH 1 AND 2.

    When combining other filters with the GUID filter, please note the GUID filter should be added last. Otherwise, preselected data may be lost. For example, a predefined filter from Featured Datasets may select a subset of data available for a subject. When combined with a GUID filter for the same subject, the filter cart will contain all data available from that subject, data structure, and dataset; this may be more data than was selected in the predefined filter for that subject. Again, you should add the GUID Filter as the last filter to your cart. This ensures 'AND' logic between filters and will limit results to the subjects, data structures, and datasets already included in your filter cart.

  • Viewable at the top right of NDA pages, the Filter Cart is a temporary holder of data identified by the user, through querying or browsing, as being of some potential interest. The Filter Cart is where you send the data from your Workspace after it has been filtered.

  • After filters are added to the Filter Cart, users have options to ‘Create a Package’ for download, ‘Associate to Study Cohort’, or ‘Find All Subject Data’. Selecting ‘Find All Subject Data’ identifies and pulls all data for the subjects into the Filter Cart. Choosing ‘Create a Package’ allows users to package and name their query information for download. Choosing ‘Associate to Study Cohort’ gives users the opportunity to choose the Study Cohort they wish to associate this data.

Glossary

  • Once your filter cart contains the subjects of interest, select Create Data Package/Assign to Data Study which will provide options for accessing item level data and/or assigning to a study.  

  • Once queries have been added to your workspace, the next step is to Submit the Filters in the workspace to the Filter Cart.  This process runs the queries selected, saving the results within a filter cart attached to your account.  

  • The Workspace within the General Query Tool is a holding area where you can review your pending filters prior to adding them to Filter Cart. Therefore, the first step in accessing data is to select one or more items and move it into the Workspace. 

NDA Help Center

Login Dialog

Frequently Asked Questions

Glossary

NDA Help Center

Collection - Associated Studies

Clicking on the Study Title will open the study details in a new internet browser tab. The Abstract is available for viewing, providing the background explanation of the study, as provided by the Collection Owner. 

Primary v. Secondary Analysis: The Data Usage column will have one of these two choices. An associated study that is listed as being used for Primary Analysis indicates at least some and potentially all of the data used was originally collected by the creator of the NDA Study. Secondary Analysis indicates the Study owner was not involved in the collection of data, and may be used as supporting data. 

Private v. Shared State: Studies that remain private indicate the associated study is only available to users who are able to access the collection. A shared study is accessible to the general public. 

Frequently Asked Questions

  • Studies are associated to the Collection automatically when the data is defined in the Study. 

Glossary

  • A tab in a Collection that lists the NDA Studies that have been created using data from that Collection including both Primary and Secondary Analysis NDA Studies.

Loading...

Login
Reset Password

NDA provides a single access to de-identified autism research data. For permission to download data, you will need an NDA account with approved access to NDA or a connected repository (AGRE, IAN, or the ATP). For NDA access, you need to be a research investigator sponsored by an NIH recognized institution with federal wide assurance. See Request Access for more information.

Warning Notice

This is a U.S. Government computer system, which may be accessed and used only for authorized Government business by authorized personnel. Unauthorized access or use of this computer system may subject violators to criminal, civil, and/or administrative action. All information on this computer system may be intercepted, recorded, read, copied, and disclosed by and to authorized personnel for official purposes, including criminal investigations. Such information includes sensitive data encrypted to comply with confidentiality and privacy requirements. Access or use of this computer system by any person, whether authorized or unauthorized, constitutes consent to these terms. There is no right of privacy in this system.

Update Password

You have logged in with a temporary password. Please update your password. Passwords must contain 8 or more characters and must contain at least 3 of the following types of characters:

  • Uppercase
  • Lowercase
  • Numbers
  • Special Characters limited to: %,_,!,@,#,$,-,%,&,+,=,),(,*,^,:,;

Subscribe to our mailing list

Mailing List(s)
Email Format

You are now leaving the NIMH Data Archive (NDA) web site to go to:

Click on the address above if the page does not change within 10 seconds.

Disclaimer

NDA is not responsible for the content of this external site and does not monitor other web sites for accuracy.

Accept Terms
Filter Cart
No filters selected
Description
Value Range
Notes
Data Structures with shared data
No filters have been selected
Switch User

1 Numbers reported are subjects by age
New Trial
New Project

Format should be in the following format: Activity Code, Institute Abbreviation, and Serial Number. Grant Type, Support Year, and Suffix should be excluded. For example, grant 1R01MH123456-01A1 should be entered R01MH123456

Please select an experiment type below

Collection - Use Existing Experiment

To associate an experiment to the current collection, just select an axperiment from the table below then click the associate experiment button to persist your changes (saving the collection is not required). Note that once an experiment has been associated to two or more collections, the experiment will not longer be editable.

The table search feature is case insensitive and targets the experiment id, experiment name and experiment type columns. The experiment id is searched only when the search term entered is a number, and filtered using a startsWith comparison. When the search term is not numeric the experiment name is used to filter the results.

SelectExperiment IdExperiment NameExperiment Type
  • Select One
  • EEG
  • EGG
  • Eye Tracking
  • Omics
  • fMRI
Created On
1869RRAY fMRI ScanfMRI11/27/2021
1867Resting StatefMRI11/22/2021
1866MNA fMRIfMRI11/16/2021
1865Motion AftereffectsEye Tracking11/05/2021
1864Tilt Aftereffects (TAE)Eye Tracking11/05/2021
1863Negative Afterimages (AI)Eye Tracking11/05/2021
1862Face-Matching TaskfMRI11/03/2021
1861Resting StatefMRI11/03/2021
1860CARIT (Go/NoGo Task)fMRI11/03/2021
1859PCR-free sequencingOmics10/29/2021
1858GNG Anger, Gender, Happy Tasks- EEGEEG10/15/2021
1857PVDM, imaging sessionEye Tracking10/14/2021
1856PVDM, imaging sessionfMRI10/13/2021
1855PVDM, behavioral sessionEye Tracking10/13/2021
1854Cerebellar Dysfunction in Autism: resting state fMRIfMRI10/13/2021
1852snRNAseq_controls_DLPFC/sgACCOmics09/30/2021
1851Reappraisal Emotion Regulation Task - V2fMRI09/22/2021
1850Reappraisal Emotion Regulation Task - V1fMRI09/22/2021
1849Stop-Signal Arrows - Randomization BfMRI09/22/2021
1848Stop-Signal Arrows - Randomization AfMRI09/22/2021
1847NPU Threat Countdown Short - V2fMRI09/22/2021
1846NPU Threat Countdown Short - V1fMRI09/22/2021
1836Alcohol Cue ReactivityEEG09/02/2021
1835Doors Reward ParadigmEEG08/30/2021
1834Flanker ArrowsEEG08/30/2021
1833Transcriptomic data of Clozapine-treated Ngn2-induced Human Excitatory NeuronsOmics08/20/2021
1830Illumina Global Screening ArrayOmics08/02/2021
1829Single-cell multiome sequencing: ATAC-seqOmics07/26/2021
1828Single-cell multiome sequencing - RNA-seqOmics07/26/2021
1827scATACseqOmics07/26/2021
1826scRNAseqOmics07/26/2021
1825Fetal Resting-state fMRI Brain MasksfMRI07/23/2021
1824Apex of Cognitive ControlfMRI07/22/2021
1823Face adaptationEye Tracking07/21/2021
1822Presaccadic AttentionEye Tracking07/21/2021
1821templefMRI07/19/2021
1820parvizi_eeg_145EEG07/16/2021
1819parvizi_eeg_166EEG07/16/2021
1818parvizi_eeg_164EEG07/16/2021
1817parvizi_eeg_165EEG07/16/2021
1816parvizi_eeg_162EEG07/16/2021
1815parvizi_eeg_161EEG07/16/2021
1814eeg_parvizi_160EEG07/16/2021
1813parvizi_eeg_159EEG07/16/2021
1812Singleton distractor rejectionEEG07/16/2021
1810InterlayerfMRI07/15/2021
1809Alpha, BOLD, experience, and expectancy during associative learningEEG07/14/2021
1808Alpha, BOLD, experience, and expectancy during associative learningfMRI07/14/2021
1807Correlating concurrent EEG/BOLD in occipital cortex while presenting Gabor patch steadily increasing in contrastEEG07/14/2021
1806Correlating concurrent EEG/BOLD in occipital cortex while presenting Gabor patch steadily increasing in contrastfMRI07/14/2021
Collection - Add Experiment
Add Supporting Documentation
Select File

Please enter the name of the data structure to search or if your definition does not exist, please upload that definition so that it can be appropriately defined for submission. Multiple data structures may be associated with a single Data Expected entry. Please add only one data structure per assessment.

Request Submission Exemption
Characters Remaining:
Not Eligible

The Data Expected list for this Collection shows some data as missing. Contact the NDA Help Desk with any questions.

Collection Updated

Your Collection is now in Data Analysis phase and exempt from biannual submissions. Data is still expected prior to publication or no later than the project end date.

[CMS] Attention

Please confirm that you will not be enrolling any more subjects and that all data has been collected and submitted.

[CMS] Error

Unable to change collection phase where targeted enrollment is less than 90%

Delete Submission Exemption
Are you sure you want to delete this submission exemption?
You have requested to move the sharing dates for the following assessments:
Data Expected Item Original Sharing Date New Sharing Date

Please provide a reason for this change, which will be sent to the Program Officers listed within this collection:

Explanation must be between 20 and 200 characters in length.

Please press Save or Cancel
Add New Email Address - Dialog
New Email Address
Shared
Collection Summary Collection Charts
Collection Title Collection Investigators Collection Description
Studies to Advance Autism Research and Treatment (STAART).
Aylward, Elizabeth; Buxbaum, Joseph; Dawson, Geraldine; Hollander, Eric; Landa, Rebecca; Rodier, Patricia; Sigman, Marian; Tager-Flusberg, Helen  
The STAART Network is comprised of eight centers across the country. Most of these centers are evaluating and treating patients, as well as enrolling them into clinical trials.
NIMH Data Archive
NIMH Data Archive
Funding Completed
Close Out
Shared
No
$17,224,763.00
2,088
Loading Chart...
NIH - Extramural None

CPEA_STAART_data_release_10182010.pdf Methods Overview of the CPEA/STAART Data Organization Qualified Researchers
CPEA_STAART_DATA_DICTIONARY.xlsx Other Data Definition of CPEA STAART Data Warehouse Qualified Researchers
assessment_to_Version_variable_mapping.xlsx Other Assessment to Version Variable Mapping Qualified Researchers

U54MH066397-01 Genotype and Phenotype of Response to Treatments of Autism 05/13/2003 04/30/2008 379 389 UNIVERSITY OF ROCHESTER $1,538,082.00
U54MH068172-01 Social & Language Deficits in Autism-Biology & Treament 05/13/2003 04/30/2008 2766 475 UNIVERSITY OF CALIFORNIA LOS ANGELES $1,851,019.00
U54MH066399-01 UW Autism Research Center of Excellence 05/13/2003 04/30/2008 240 223 UNIVERSITY OF WASHINGTON $5,001,997.00
U54MH066417-01 NEUROBIOLOGIC ORIGINS AND INNOVATIVE TREATMENT OF AUTISM 05/13/2003 04/30/2010 246 358 HUGO W. MOSER RES INST KENNEDY KRIEGER $7,086,470.00
U54MH066673-01 Greater New York Autism Research Center of Excellence 05/13/2003 04/30/2008 806 496 ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI $1,747,195.00

IDNameCreated DateStatusType
No records found.

Collection Owners and those with Collection Administrator permission, may edit a collection. The following is currently available for Edit on this page:

Shared Data

Data structures with the number of subjects submitted and shared are provided.

Autism Diagnostic Interview, Revised (ADI-R) Clinical Assessments 31
Autism Diagnostic Observation Schedule (ADOS)- Module 1 Clinical Assessments 35
Autism Diagnostic Observation Schedule (ADOS)- Module 2 Clinical Assessments 16
Autism Diagnostic Observation Schedule (ADOS)- Module 3 Clinical Assessments 13
CPEA STAART ABC 1994 Clinical Assessments 180
CPEA STAART ADI 1991 Toddler Clinical Assessments 62
CPEA STAART ADI 2003 Clinical Assessments 816
CPEA STAART ADI-R 1995 Short Clinical Assessments 2
CPEA STAART ADI-R 1998 Long Clinical Assessments 155
CPEA STAART ADI-R 1999 Short Clinical Assessments 71
CPEA STAART ADOS G Module 1 Clinical Assessments 60
CPEA STAART ADOS G Module 2 Clinical Assessments 36
CPEA STAART ADOS G Module 3 Clinical Assessments 66
CPEA STAART ADOS G Module 4 Clinical Assessments 10
CPEA STAART ADOS WPS Module 1 Clinical Assessments 697
CPEA STAART ADOS WPS Module 2 Clinical Assessments 181
CPEA STAART ADOS WPS Module 3 Clinical Assessments 308
CPEA STAART ADOS WPS Module 4 Clinical Assessments 180
CPEA STAART CBCL 1.5 to 5 Clinical Assessments 141
CPEA STAART CBCL 6 to 18 Clinical Assessments 138
CPEA STAART CTOPP Ages 5 to 6 Clinical Assessments 13
CPEA STAART CTOPP Ages 7 to 24 Clinical Assessments 321
CPEA STAART CYBOCS 1999 Clinical Assessments 164
CPEA STAART EVT Clinical Assessments 27
CPEA STAART Expressive One Word Pic Vocab Test Clinical Assessments 272
CPEA STAART General Variables Clinical Assessments 2053
CPEA STAART Leiter Scales Clinical Assessments 139
CPEA STAART MacArthur-Bates Words and Gestures Clinical Assessments 171
CPEA STAART MacArthur-Bates Words and Sentences Clinical Assessments 101
CPEA STAART Mullen Clinical Assessments 757
CPEA STAART P-DAS Clinical Assessments 5
CPEA STAART PDDBI Clinical Assessments 19
CPEA STAART PLS_4 Clinical Assessments 90
CPEA STAART PPVT SUMMARY 2004 Clinical Assessments 55
CPEA STAART PPVT Version 3 Clinical Assessments 494
CPEA STAART Reynell Clinical Assessments 53
CPEA STAART S-DAS Clinical Assessments 5
CPEA STAART SRS Clinical Assessments 19
CPEA STAART Sensory Profile 3 to 10 Years Clinical Assessments 239
CPEA STAART Sensory Profile 7 - 36 Months Clinical Assessments 41
CPEA STAART Stanford Binet 4th Edition Clinical Assessments 1
CPEA STAART Stanford Binet 5th Edition Clinical Assessments 63
CPEA STAART Vineland I Clinical Assessments 1322
CPEA STAART WAIS 3 Clinical Assessments 55
CPEA STAART WASI Clinical Assessments 258
CPEA STAART WISC 3 Clinical Assessments 40
CPEA STAART WISC 4 Clinical Assessments 206
CPEA STAART WPPSI 2y6m to 3y11m Clinical Assessments 16
DAS-II: Differential Ability Scales 2nd Ed. School Age Clinical Assessments 16
DAS-II:Differential Ability Scales 2nd Ed. Early Years Clinical Assessments 4
Mullen Scales of Early Learning Clinical Assessments 33
Social Communication Questionnaire (SCQ) - Current Form Clinical Assessments 1
Social Communication Questionnaire (SCQ) - Lifetime Clinical Assessments 7

Collection Owners and those with Collection Administrator permission, may edit a collection. The following is currently available for Edit on this page:

Publications

Publications relevant to NDA data are listed below. Most displayed publications have been associated with the grant within Pubmed. Use the "+ New Publication" button to add new publications. Publications relevant/not relevant to data expected are categorized. Relevant publications are then linked to the underlying data by selecting the Create Study link. Study provides the ability to define cohorts, assign subjects, define outcome measures and lists the study type, data analysis and results. Analyzed data and results are expected in this way.

PubMed IDStudyTitleJournalAuthorsDateStatus
34504056Create StudySterol and lipid analyses identifies hypolipidemia and apolipoprotein disorders in autism associated with adaptive functioning deficits.Translational psychiatryTierney, Elaine; Remaley, Alan T; Thurm, Audrey; Jager, Leah R; Wassif, Christopher A; Kratz, Lisa E; Bailey-Wilson, Joan E; Bukelis, Irena; Sarphare, Geeta; Jung, Eun Sol; Brand, Boudewien; Noah, Kelly K; Porter, Forbes DSeptember 9, 2021Not Determined
34309743Create StudyThe Early Start Denver Model Intervention and Mu Rhythm Attenuation in Autism Spectrum Disorders.Journal of autism and developmental disordersAaronson, Benjamin; Estes, Annette; Rogers, Sally J; Dawson, Geraldine; Bernier, RaphaelJuly 26, 2021Not Determined
32333300Create StudyBrief Report: Performance-Based Executive Functioning Abilities are Associated with Caregiver Report of Adaptive Functioning in Autism Spectrum Disorder.Journal of autism and developmental disordersUdhnani, Manisha D; Kenworthy, Lauren; Wallace, Gregory L; Yerys, Benjamin EDecember 2020Not Determined
32140983Create StudySleep Problems and Trajectories of Restricted and Repetitive Behaviors in Children with Neurodevelopmental Disabilities.Journal of autism and developmental disordersMacDuffie, Katherine E; Munson, Jeffrey; Greenson, Jessica; Ward, Teresa M; Rogers, Sally J; Dawson, Geraldine; Estes, AnnetteNovember 1, 2020Not Determined
30628809Create StudyEarly motor abilities in infants at heightened versus low risk for ASD: A Baby Siblings Research Consortium (BSRC) study.Journal of abnormal psychologyIverson, Jana M; Shic, Frederick; Wall, Carla A; Chawarska, Katarzyna; Curtin, Suzanne; Estes, Annette; Gardner, Judith M; Hutman, Ted; Landa, Rebecca J; Levin, April R; Libertus, Klaus; Messinger, Daniel S; Nelson, Charles A; Ozonoff, Sally; Sacrey, Lori-Ann R; Sheperd, Kelly; Stone, Wendy L; Tager-Flusberg, Helen B; Wolff, Jason J; Yirmiya, Nurit; Young, Gregory SJanuary 2019Not Determined
30506566Create StudyThe dysregulation profile in preschoolers with and without a family history of autism spectrum disorder.Journal of child psychology and psychiatry, and allied disciplinesMiller, Meghan; Iosif, Ana-Maria; Young, Gregory S; Bell, Laura J; Schwichtenberg, A J; Hutman, Ted; Ozonoff, SallyMay 2019Not Determined
28970862Create StudyUtility of the CBCL DSM-Oriented Scales in Assessing Emotional Disorders in Youth with Autism.Research in autism spectrum disordersMagyar, Caroline I; Pandolfi, VincentMay 2017Not Determined
28889315Create StudyBrief Report: Executive Function as a Predictor of Academic Achievement in School-Aged Children with ASD.Journal of autism and developmental disordersSt John, Tanya; Dawson, Geraldine; Estes, AnnetteJanuary 2018Not Determined
28838582Create StudyCost Offset Associated With Early Start Denver Model for Children With Autism.Journal of the American Academy of Child and Adolescent PsychiatryCidav Z, Munson J, Estes A, Dawson G, Rogers S, Mandell DSeptember 2017Not Determined
28371492Create StudyI tawt i taw a puddy tat: Gestures in canary row narrations by high-functioning youth with autism spectrum disorder.Autism research : official journal of the International Society for Autism ResearchSilverman LB, Eigsti IM, Bennetto LAugust 2017Not Determined
27940149Create StudyClose genetic relationships between a spousal pair with autism-affected children and high minor allele content in cases in autism-associated SNPs.GenomicsZhu Z, Lu X, Yuan D, Huang SJanuary 2017Not Determined
27620949Create StudyCharacteristics of socially successful elementary school-aged children with autism.Journal of child psychology and psychiatry, and allied disciplinesLocke, Jill; Williams, Justin; Shih, Wendy; Kasari, ConnieJanuary 2017Not Determined
27417857Create StudyNon-ASD outcomes at 36 months in siblings at familial risk for autism spectrum disorder (ASD): A baby siblings research consortium (BSRC) study.Autism research : official journal of the International Society for Autism ResearchCharman, Tony; Young, Gregory S; Brian, Jessica; Carter, Alice; Carver, Leslie J; Chawarska, Katarzyna; Curtin, Suzanne; Dobkins, Karen; Elsabbagh, Mayada; Georgiades, Stelios; Hertz-Picciotto, Irva; Hutman, Ted; Iverson, Jana M; Jones, Emily J; Landa, Rebecca; Macari, Suzanne; Messinger, Daniel S; Nelson, Charles A; Ozonoff, Sally; Saulnier, Celine; Stone, Wendy L; Tager-Flusberg, Helen; Webb, Sara Jane; Yirmiya, Nurit; Zwaigenbaum, LonnieJanuary 2017Not Determined
27358719Create StudyCommentary: sex difference differences? A reply to Constantino.Molecular autismMessinger, Daniel S; Young, Gregory S; Webb, Sara Jane; Ozonoff, Sally; Bryson, Susan E; Carter, Alice; Carver, Leslie; Charman, Tony; Chawarska, Katarzyna; Curtin, Suzanne; Dobkins, Karen; Hertz-Picciotto, Irva; Hutman, Ted; Iverson, Jana M; Landa, Rebecca; Nelson, Charles A; Stone, Wendy L; Tager-Flusberg, Helen; Zwaigenbaum, Lonnie2016Not Relevant
27178863Create StudyEarly event-related potentials to emotional faces differ for adults with autism spectrum disorder and by serotonin transporter genotype.Clinical neurophysiology : official journal of the International Federation of Clinical NeurophysiologyFaja, Susan; Dawson, Geraldine; Aylward, Elizabeth; Wijsman, Ellen M; Webb, Sara JaneJune 2016Not Determined
26966285Create StudyRace, disability, and grade: Social relationships in children with autism spectrum disorders.Autism : the international journal of research and practiceAzad, Gazi F; Locke, Jill; Kasari, Connie; Mandell, David SJanuary 2017Not Determined
26890821Create StudyExecutive function predicts the development of play skills for verbal preschoolers with autism spectrum disorders.Autism research : official journal of the International Society for Autism ResearchFaja, Susan; Dawson, Geraldine; Sullivan, Katherine; Meltzoff, Andrew N; Estes, Annette; Bernier, RaphaelDecember 2016Not Determined
26881074Create StudyTheory of Mind Indexes the Broader Autism Phenotype in Siblings of Children with Autism at School Age.Autism research and treatmentTsang T, Gillespie-Lynch K, Hutman TJanuary 2016Not Determined
26567264Create StudySocial network analysis of children with autism spectrum disorder: Predictors of fragmentation and connectivity in elementary school classrooms.Autism : the international journal of research and practiceAnderson, Ariana; Locke, Jill; Kretzmann, Mark; Kasari, Connie; AIR-B NetworkAugust 2016Not Determined
26484047Create StudyDefault mode network segregation and social deficits in autism spectrum disorder: Evidence from non-medicated children.NeuroImage. ClinicalYerys, Benjamin E; Gordon, Evan M; Abrams, Danielle N; Satterthwaite, Theodore D; Weinblatt, Rachel; Jankowski, Kathryn F; Strang, John; Kenworthy, Lauren; Gaillard, William D; Vaidya, Chandan J2015Not Determined
26451968Create StudySchool-age outcomes of infants at risk for autism spectrum disorder.Autism research : official journal of the International Society for Autism ResearchMiller, Meghan; Iosif, Ana-Maria; Young, Gregory S; Hill, Monique; Phelps Hanzel, Elise; Hutman, Ted; Johnson, Scott; Ozonoff, SallyJune 1, 2016Not Determined
26343026Create StudyThe Gluten-Free/Casein-Free Diet: A Double-Blind Challenge Trial in Children with Autism.Journal of autism and developmental disordersHyman, Susan L; Stewart, Patricia A; Foley, Jennifer; Cain, Usa; Peck, Robin; Morris, Danielle D; Wang, Hongyue; Smith, TristramJanuary 2016Not Determined
26340957Create StudyAltered Dynamics of the fMRI Response to Faces in Individuals with Autism.Journal of autism and developmental disordersKleinhans, Natalia M; Richards, Todd; Greenson, Jessica; Dawson, Geraldine; Aylward, ElizabethJanuary 2016Not Determined
26236149Create StudyAnterior-Posterior Connectivity within the Default Mode Network Increases During Maturation.International journal of medical and biological frontiersWashington, Stuart D; VanMeter, John W2015Not Relevant
26164418Create StudyInfants'' behavioral styles in joint attention situations and parents'' socio-economic status.Infant behavior & developmentAbels, Monika; Hutman, TedAugust 2015Not Determined
26088663Create StudyLong-Term Outcomes of Early Intervention in 6-Year-Old Children With Autism Spectrum Disorder.Journal of the American Academy of Child and Adolescent PsychiatryEstes, Annette; Munson, Jeffrey; Rogers, Sally J; Greenson, Jessica; Winter, Jamie; Dawson, GeraldineJuly 2015Not Relevant
26045943Create StudyEarly sex differences are not autism-specific: A Baby Siblings Research Consortium (BSRC) study.Molecular autismMessinger, Daniel S; Young, Gregory S; Webb, Sara Jane; Ozonoff, Sally; Bryson, Susan E; Carter, Alice; Carver, Leslie; Charman, Tony; Chawarska, Katarzyna; Curtin, Suzanne; Dobkins, Karen; Hertz-Picciotto, Irva; Hutman, Ted; Iverson, Jana M; Landa, Rebecca; Nelson, Charles A; Stone, Wendy L; Tager-Flusberg, Helen; Zwaigenbaum, LonnieJanuary 2015Not Determined
25898050Create StudyEffect of parent training vs parent education on behavioral problems in children with autism spectrum disorder: a randomized clinical trial.JAMABearss, Karen; Johnson, Cynthia; Smith, Tristram; Lecavalier, Luc; Swiezy, Naomi; Aman, Michael; McAdam, David B; Butter, Eric; Stillitano, Charmaine; Minshawi, Noha; Sukhodolsky, Denis G; Mruzek, Daniel W; Turner, Kylan; Neal, Tiffany; Hallett, Victoria; Mulick, James A; Green, Bryson; Handen, Benjamin; Deng, Yanhong; Dziura, James; Scahill, LawrenceApril 21, 2015Not Determined
25778537Create StudyPredicting Outcome of Community-Based Early Intensive Behavioral Intervention for Children with Autism.Journal of abnormal child psychologySmith, Tristram; Klorman, Rafael; Mruzek, Daniel WOctober 2015Not Determined
25599972Create StudyNeural Correlates of Set-Shifting in Children With Autism.Autism research : official journal of the International Society for Autism ResearchYerys, Benjamin E; Antezana, Ligia; Weinblatt, Rachel; Jankowski, Kathryn F; Strang, John; Vaidya, Chandan J; Schultz, Robert T; Gaillard, William D; Kenworthy, LaurenAugust 2015Not Relevant
25457930Create Study18-month predictors of later outcomes in younger siblings of children with autism spectrum disorder: a baby siblings research consortium study.Journal of the American Academy of Child and Adolescent PsychiatryChawarska, Katarzyna; Shic, Frederick; Macari, Suzanne; Campbell, Daniel J; Brian, Jessica; Landa, Rebecca; Hutman, Ted; Nelson, Charles A; Ozonoff, Sally; Tager-Flusberg, Helen; Young, Gregory S; Zwaigenbaum, Lonnie; Cohen, Ira L; Charman, Tony; Messinger, Daniel S; Klin, Ami; Johnson, Scott; Bryson, SusanDecember 2014Not Determined
25409314Create StudyProtein interaction networks reveal novel autism risk genes within GWAS statistical noise.PloS oneCorreia, Catarina; Oliveira, Guiomar; Vicente, Astrid M2014Not Determined
25315782Create StudyEarly pragmatic language difficulties in siblings of children with autism: implications for DSM-5 social communication disorder?Journal of child psychology and psychiatry, and allied disciplinesMiller, Meghan; Young, Gregory S; Hutman, Ted; Johnson, Scott; Schwichtenberg, A J; Ozonoff, SallyJuly 2015Not Determined
25313971Create StudyPediatric status epilepticus: identification and evaluation.Current opinion in pediatricsFreilich, Emily R; Schreiber, John M; Zelleke, Tesfaye; Gaillard, William DDecember 2014Not Determined
25108609Create StudyPotential neural mechanisms underlying the effectiveness of early intervention for children with autism spectrum disorder.Research in developmental disabilitiesSullivan, Katherine; Stone, Wendy L; Dawson, GeraldineNovember 2014Not Determined
25039696Create StudyThe peer relationships of girls with ASD at school: comparison to boys and girls with and without ASD.Journal of child psychology and psychiatry, and allied disciplinesDean M, Kasari C, Shih W, Frankel F, Whitney R, Landa R, Lord C, Orlich F, King B, Harwood RNovember 2014Not Determined
25038753Create StudyMost genetic risk for autism resides with common variation.Nature geneticsGaugler, Trent; Klei, Lambertus; Sanders, Stephan J; Bodea, Corneliu A; Goldberg, Arthur P; Lee, Ann B; Mahajan, Milind; Manaa, Dina; Pawitan, Yudi; Reichert, Jennifer; Ripke, Stephan; Sandin, Sven; Sklar, Pamela; Svantesson, Oscar; Reichenberg, Abraham; Hultman, Christina M; Devlin, Bernie; Roeder, Kathryn; Buxbaum, Joseph DAugust 2014Not Determined
24655649Create StudyThe broader autism phenotype in infancy: when does it emerge?Journal of the American Academy of Child and Adolescent PsychiatryOzonoff S, Young GS, Belding A, Hill M, Hill A, Hutman T, Johnson S, Miller M, Rogers SJ, Schwichtenberg AJ, Steinfeld M, Iosif AMApril 2014Not Determined
24108192Create StudyPredicting treatment success in social skills training for adolescents with autism spectrum disorders: the UCLA Program for the Education and Enrichment of Relational Skills.Autism : the international journal of research and practiceChang YC, Laugeson EA, Gantman A, Ellingsen R, Frankel F, Dillon ARMay 2014Not Determined
24061784Create StudyBaseline factors predicting placebo response to treatment in children and adolescents with autism spectrum disorders: a multisite randomized clinical trial.JAMA pediatricsKing, Bryan H; Dukes, Kimberly; Donnelly, Craig L; Sikich, Linmarie; McCracken, James T; Scahill, Lawrence; Hollander, Eric; Bregman, Joel D; Anagnostou, Evdokia; Robinson, Fay; Sullivan, Lisa; Hirtz, DeborahNovember 2013Not Determined
23996903Create StudyLong-term outcomes of parent-assisted social skills intervention for high-functioning children with autism spectrum disorders.Autism : the international journal of research and practiceMandelberg J, Frankel F, Cunningham T, Gorospe C, Laugeson EAApril 2014Not Determined
23894004Create StudyReduced serotonin receptor subtypes in a limbic and a neocortical region in autism.Autism research : official journal of the International Society for Autism ResearchOblak A, Gibbs TT, Blatt GJDecember 2013Not Determined
23880382Create StudyInterests in high-functioning autism are more intense, interfering, and idiosyncratic than those in neurotypical development.Development and psychopathologyAnthony, Laura Gutermuth; Kenworthy, Lauren; Yerys, Benjamin E; Jankowski, Kathryn F; James, Joette D; Harms, Madeline B; Martin, Alex; Wallace, Gregory LAugust 2013Not Determined
23820765Create StudyParent-reported temperament trajectories among infant siblings of children with autism.Journal of autism and developmental disordersDel Rosario, Mithi; Gillespie-Lynch, Kristen; Johnson, Scott; Sigman, Marian; Hutman, TedFebruary 2014Not Determined
23734230Create StudyBrain responses to words in 2-year-olds with autism predict developmental outcomes at age 6.PloS oneKuhl, Patricia K; Coffey-Corina, Sharon; Padden, Denise; Munson, Jeffrey; Estes, Annette; Dawson, Geraldine2013Not Determined
23452686Create StudyBeyond autism: a baby siblings research consortium study of high-risk children at three years of age.Journal of the American Academy of Child and Adolescent PsychiatryMessinger, Daniel; Young, Gregory S; Ozonoff, Sally; Dobkins, Karen; Carter, Alice; Zwaigenbaum, Lonnie; Landa, Rebecca J; Charman, Tony; Stone, Wendy L; Constantino, John N; Hutman, Ted; Carver, Leslie J; Bryson, Susan; Iverson, Jana M; Strauss, Mark S; Rogers, Sally J; Sigman, MarianMarch 2013Not Determined
23436793Create StudyBehavior and sleep problems in children with a family history of autism.Autism research : official journal of the International Society for Autism ResearchSchwichtenberg, Amy Jo; Young, Gregory S; Hutman, Ted; Iosif, Ana-Maria; Sigman, Marian; Rogers, Sally J; Ozonoff, SallyJune 2013Not Determined
23400347Create StudyExploring the manifestations of anxiety in children with autism spectrum disorders.Journal of autism and developmental disordersHallett, Victoria; Lecavalier, Luc; Sukhodolsky, Denis G; Cipriano, Noreen; Aman, Michael G; McCracken, James T; McDougle, Christopher J; Tierney, Elaine; King, Bryan H; Hollander, Eric; Sikich, Linmarie; Bregman, Joel; Anagnostou, Evdokia; Donnelly, Craig; Katsovich, Lily; Dukes, Kimberly; Vitiello, Benedetto; Gadow, Kenneth; Scahill, LawrenceOctober 2013Not Determined
23336424Create StudyEarly sensory over-responsivity in toddlers with autism spectrum disorders as a predictor of family impairment and parenting stress.Journal of child psychology and psychiatry, and allied disciplinesBen-Sasson, A; Soto, T W; Martínez-Pedraza, F; Carter, A SAugust 2013Not Determined
23334984Create StudyDysmaturation of the default mode network in autism.Human brain mappingWashington, Stuart D; Gordon, Evan M; Brar, Jasmit; Warburton, Samantha; Sawyer, Alice T; Wolfe, Amanda; Mease-Ference, Erin R; Girton, Laura; Hailu, Ayichew; Mbwana, Juma; Gaillard, William D; Kalbfleisch, M Layne; VanMeter, John WApril 2014Not Determined
23146332Create StudyParenting-related stress and psychological distress in mothers of toddlers with autism spectrum disorders.Brain & developmentEstes, Annette; Olson, Erin; Sullivan, Katherine; Greenson, Jessica; Winter, Jamie; Dawson, Geraldine; Munson, JeffreyFebruary 2013Not Determined
23130085Create StudyDo Social Attribution Skills Improve with Age in Children with High Functioning Autism Spectrum Disorders?Research in autism spectrum disordersBal, Elgiz; Yerys, Benjamin E; Sokoloff, Jennifer L; Celano, Mark J; Kenworthy, Lauren; Giedd, Jay N; Wallace, Gregory LJanuary 2013Not Determined
23110514Create StudyDevelopmental trajectories in children with and without autism spectrum disorders: the first 3 years.Child developmentLanda, Rebecca J; Gross, Alden L; Stuart, Elizabeth A; Faherty, AshleyMarch 2013Not Determined
23101741Create StudyEarly behavioral intervention is associated with normalized brain activity in young children with autism.Journal of the American Academy of Child and Adolescent PsychiatryDawson, Geraldine; Jones, Emily J H; Merkle, Kristen; Venema, Kaitlin; Lowy, Rachel; Faja, Susan; Kamara, Dana; Murias, Michael; Greenson, Jessica; Winter, Jamie; Smith, Milani; Rogers, Sally J; Webb, Sara JNovember 2012Not Determined
23055002Create StudyInterventions addressing social impairment in autism.Current psychiatry reportsKasari C, Patterson SDecember 2012Not Determined
23044707Create StudyUsing large clinical data sets to infer pathogenicity for rare copy number variants in autism cohorts.Molecular psychiatryMoreno-De-Luca, D; Sanders, S J; Willsey, A J; Mulle, J G; Lowe, J K; Geschwind, D H; State, M W; Martin, C L; Ledbetter, D HOctober 2013Not Determined
22982285Create StudyRelation between early motor delay and later communication delay in infants at risk for autism.Infant behavior & developmentBhat AN, Galloway JC, Landa RJDecember 2012Not Determined
22843504Create StudyIndividual common variants exert weak effects on the risk for autism spectrum disorders.Human molecular geneticsAnney, Richard; Klei, Lambertus; Pinto, Dalila; Almeida, Joana; Bacchelli, Elena; Baird, Gillian; Bolshakova, Nadia; Bölte, Sven; Bolton, Patrick F; Bourgeron, Thomas; Brennan, Sean; Brian, Jessica; Casey, Jillian; Conroy, Judith; Correia, Catarina; Corsello, Christina; Crawford, Emily L; de Jonge, Maretha; Delorme, Richard; Duketis, Eftichia; Duque, Frederico; Estes, Annette; Farrar, Penny; Fernandez, Bridget A; Folstein, Susan E; Fombonne, Eric; Gilbert, John; Gillberg, Christopher; Glessner, Joseph T; Green, Andrew; Green, Jonathan; Guter, Stephen J; Heron, Elizabeth A; Holt, Richard; Howe, Jennifer L; Hughes, Gillian; Hus, Vanessa; Igliozzi, Roberta; Jacob, Suma; Kenny, Graham P; Kim, Cecilia; Kolevzon, Alexander; Kustanovich, Vlad; Lajonchere, Clara M; Lamb, Janine A; Law-Smith, Miriam; Leboyer, Marion; Le Couteur, Ann; Leventhal, Bennett L; Liu, Xiao-Qing; Lombard, Frances; Lord, Catherine; Lotspeich, Linda; Lund, Sabata C; Magalhaes, Tiago R; Mantoulan, Carine; McDougle, Christopher J; Melhem, Nadine M; Merikangas, Alison; Minshew, Nancy J; Mirza, Ghazala K; Munson, Jeff; Noakes, Carolyn; Nygren, Gudrun; Papanikolaou, Katerina; Pagnamenta, Alistair T; Parrini, Barbara; Paton, Tara; Pickles, Andrew; Posey, David J; Poustka, Fritz; Ragoussis, Jiannis; Regan, Regina; Roberts, Wendy; Roeder, Kathryn; Roge, Bernadette; Rutter, Michael L; Schlitt, Sabine; Shah, Naisha; Sheffield, Val C; Soorya, Latha; Sousa, Inês; Stoppioni, Vera; Sykes, Nuala; Tancredi, Raffaella; Thompson, Ann P; Thomson, Susanne; Tryfon, Ana; Tsiantis, John; Van Engeland, Herman; Vincent, John B; Volkmar, Fred; Vorstman, J A S; Wallace, Simon; Wing, Kirsty; Wittemeyer, Kerstin; Wood, Shawn; Zurawiecki, Danielle; Zwaigenbaum, Lonnie; Bailey, Anthony J; Battaglia, Agatino; Cantor, Rita M; Coon, Hilary; Cuccaro, Michael L; Dawson, Geraldine; Ennis, Sean; Freitag, Christine M; Geschwind, Daniel H; Haines, Jonathan L; Klauck, Sabine M; McMahon, William M; Maestrini, Elena; Miller, Judith; Monaco, Anthony P; Nelson, Stanley F; Nurnberger Jr, John I; Oliveira, Guiomar; Parr, Jeremy R; Pericak-Vance, Margaret A; Piven, Joseph; Schellenberg, Gerard D; Scherer, Stephen W; Vicente, Astrid M; Wassink, Thomas H; Wijsman, Ellen M; Betancur, Catalina; Buxbaum, Joseph D; Cook, Edwin H; Gallagher, Louise; Gill, Michael; Hallmayer, Joachim; Paterson, Andrew D; Sutcliffe, James S; Szatmari, Peter; Vieland, Veronica J; Hakonarson, Hakon; Devlin, BernieNovember 1, 2012Not Determined
22728336Create StudyInfants' pre-empathic behaviors are associated with language skills.Infant behavior & developmentHutman T, Rozga A, DeLaurentis A, Sigman M, Dapretto MJune 2012Not Determined
22615713Create StudyDepression and Anxiety Symptoms in Children and Adolescents with Autism Spectrum Disorders without Intellectual Disability.Research in autism spectrum disordersStrang, John F; Kenworthy, Lauren; Daniolos, Peter; Case, Laura; Wills, Meagan C; Martin, Alex; Wallace, Gregory LJanuary 2012Not Determined
22574686Create StudyLatent class analysis of early developmental trajectory in baby siblings of children with autism.Journal of child psychology and psychiatry, and allied disciplinesLanda RJ, Gross AL, Stuart EA, Bauman MSeptember 2012Not Determined
22499558Create StudyNetwork- and attribute-based classifiers can prioritize genes and pathways for autism spectrum disorders and intellectual disability.American journal of medical genetics. Part C, Seminars in medical geneticsKou, Yan; Betancur, Catalina; Xu, Huilei; Buxbaum, Joseph D; Ma'ayan, AviMay 15, 2012Not Determined
22271196Create StudyDifferences in autism symptoms between minority and non-minority toddlers.Journal of autism and developmental disordersTek S, Landa RJSeptember 2012Not Determined
22215436Create StudyExploring the social impact of being a typical peer model for included children with autism spectrum disorder.Journal of autism and developmental disordersLocke, Jill; Rotheram-Fuller, Erin; Kasari, ConnieSeptember 2012Not Determined
22193531Create StudyA double-blind placebo-controlled trial of fluoxetine for repetitive behaviors and global severity in adult autism spectrum disorders.The American journal of psychiatryHollander E, Soorya L, Chaplin W, Anagnostou E, Taylor BP, Ferretti CJ, Wasserman S, Swanson E, Settipani CMarch 2012Not Determined
22118062Create StudyMaking the connection: randomized controlled trial of social skills at school for children with autism spectrum disorders.Journal of child psychology and psychiatry, and allied disciplinesKasari, Connie; Rotheram-Fuller, Erin; Locke, Jill; Gulsrud, AmandaApril 2012Not Determined
22079057Create StudyThe 5-HT(2A) receptor and serotonin transporter in Asperger''s disorder: A PET study with [¹¹C]MDL 100907 and [¹¹C]DASB.Psychiatry researchGirgis, Ragy R; Slifstein, Mark; Xu, Xiaoyan; Frankle, W Gordon; Anagnostou, Evdokia; Wasserman, Stacey; Pepa, Lauren; Kolevzon, Alexander; Abi-Dargham, Anissa; Laruelle, Marc; Hollander, EricDecember 30, 2011Not Determined
22059091Create StudyAn Initial Psychometric Evaluation of the CBCL 6-18 in a Sample of Youth with Autism Spectrum Disorders.Research in autism spectrum disordersPandolfi, Vincent; Magyar, Caroline I; Dill, Charles AJanuary 2012Not Determined
22010812Create StudyA simple assay to study social behavior in Drosophila: measurement of social space within a group.Genes, brain, and behaviorSimon AF, Chou MT, Salazar ED, Nicholson T, Saini N, Metchev S, Krantz DEMarch 2012Not Determined
22004249Create StudyDevelopmental change in the ERP responses to familiar faces in toddlers with autism spectrum disorders versus typical development.Child developmentWebb, Sara Jane; Jones, Emily J H; Merkle, Kristen; Venema, Kaitlin; Greenson, Jessica; Murias, Michael; Dawson, GeraldineNovember 2011Not Determined
21996756Create StudyA novel approach of homozygous haplotype sharing identifies candidate genes in autism spectrum disorder.Human geneticsCasey, Jillian P; Magalhaes, Tiago; Conroy, Judith M; Regan, Regina; Shah, Naisha; Anney, Richard; Shields, Denis C; Abrahams, Brett S; Almeida, Joana; Bacchelli, Elena; Bailey, Anthony J; Baird, Gillian; Battaglia, Agatino; Berney, Tom; Bolshakova, Nadia; Bolton, Patrick F; Bourgeron, Thomas; Brennan, Sean; Cali, Phil; Correia, Catarina; Corsello, Christina; Coutanche, Marc; Dawson, Geraldine; de Jonge, Maretha; Delorme, Richard; Duketis, Eftichia; Duque, Frederico; Estes, Annette; Farrar, Penny; Fernandez, Bridget A; Folstein, Susan E; Foley, Suzanne; Fombonne, Eric; Freitag, Christine M; Gilbert, John; Gillberg, Christopher; Glessner, Joseph T; Green, Jonathan; Guter, Stephen J; Hakonarson, Hakon; Holt, Richard; Hughes, Gillian; Hus, Vanessa; Igliozzi, Roberta; Kim, Cecilia; Klauck, Sabine M; Kolevzon, Alexander; Lamb, Janine A; Leboyer, Marion; Le Couteur, Ann; Leventhal, Bennett L; Lord, Catherine; Lund, Sabata C; Maestrini, Elena; Mantoulan, Carine; Marshall, Christian R; McConachie, Helen; McDougle, Christopher J; McGrath, Jane; McMahon, William M; Merikangas, Alison; Miller, Judith; Minopoli, Fiorella; Mirza, Ghazala K; Munson, Jeff; Nelson, Stanley F; Nygren, Gudrun; Oliveira, Guiomar; Pagnamenta, Alistair T; Papanikolaou, Katerina; Parr, Jeremy R; Parrini, Barbara; Pickles, Andrew; Pinto, Dalila; Piven, Joseph; Posey, David J; Poustka, Annemarie; Poustka, Fritz; Ragoussis, Jiannis; Roge, Bernadette; Rutter, Michael L; Sequeira, Ana F; Soorya, Latha; Sousa, Inês; Sykes, Nuala; Stoppioni, Vera; Tancredi, Raffaella; Tauber, Maïté; Thompson, Ann P; Thomson, Susanne; Tsiantis, John; Van Engeland, Herman; Vincent, John B; Volkmar, Fred; Vorstman, Jacob A S; Wallace, Simon; Wang, Kai; Wassink, Thomas H; White, Kathy; Wing, Kirsty; Wittemeyer, Kerstin; Yaspan, Brian L; Zwaigenbaum, Lonnie; Betancur, Catalina; Buxbaum, Joseph D; Cantor, Rita M; Cook, Edwin H; Coon, Hilary; Cuccaro, Michael L; Geschwind, Daniel H; Haines, Jonathan L; Hallmayer, Joachim; Monaco, Anthony P; Nurnberger Jr, John I; Pericak-Vance, Margaret A; Schellenberg, Gerard D; Scherer, Stephen W; Sutcliffe, James S; Szatmari, Peter; Vieland, Veronica J; Wijsman, Ellen M; Green, Andrew; Gill, Michael; Gallagher, Louise; Vicente, Astrid; Ennis, SeanApril 2012Not Determined
21948895Create StudyFactor analysis of repetitive behaviors in Autism as measured by the Y-BOCS.The Journal of neuropsychiatry and clinical neurosciencesAnagnostou E, Chaplin W, Watner D, Silverman JM, Smith CJ, Zagursky K, Kryzak LA, Corwin TE, Feirsen N, Tanel N, Hollander E2011Not Determined
21935727Create StudyAnxiety and sensory over-responsivity in toddlers with autism spectrum disorders: bidirectional effects across time.Journal of autism and developmental disordersGreen SA, Ben-Sasson A, Soto TW, Carter ASJune 2012Not Determined
21910524Create StudyImitation from 12 to 24 months in autism and typical development: a longitudinal Rasch analysis.Developmental psychologyYoung, Gregory S; Rogers, Sally J; Hutman, Ted; Rozga, Agata; Sigman, Marian; Ozonoff, SallyNovember 2011Not Determined
21901839Create StudyAlterations in GABAergic biomarkers in the autism brain: research findings and clinical implications.Anatomical record (Hoboken, N.J. : 2007)Blatt GJ, Fatemi SHOctober 2011Not Relevant
21858588Create StudyEvidence-based social skills training for adolescents with autism spectrum disorders: the UCLA PEERS program.Journal of autism and developmental disordersLaugeson, Elizabeth A; Frankel, Fred; Gantman, Alexander; Dillon, Ashley R; Mogil, CatherineJune 2012Not Determined
21844053Create StudyRecurrence risk for autism spectrum disorders: a Baby Siblings Research Consortium study.PediatricsOzonoff S, Young GS, Carter A, Messinger D, Yirmiya N, Zwaigenbaum L, Bryson S, Carver LJ, Constantino JN, Dobkins K, Hutman T, Iverson JM, Landa R, Rogers SJ, Sigman M, Stone WLSeptember 2011Not Determined
21667200Create StudyDesign and subject characteristics in the federally-funded citalopram trial in children with pervasive developmental disorders.Journal of autism and developmental disordersScahill, Lawrence; McCracken, James T; Bearss, Karen; Robinson, Fay; Hollander, Eric; King, Bryan; Bregman, Joel; Sikich, Lin; Dukes, Kimberly; Sullivan, Lisa; Anagnostou, Evdokia; Donnelly, Craig; Kim, Young-Shin; Ritz, Louise; Hirtz, Deborah; Wagner, AnnMarch 2012Not Determined
21598046Create StudyPredictors and course of daily living skills development in toddlers with autism spectrum disorders.Journal of autism and developmental disordersGreen, Shulamite A; Carter, Alice SFebruary 2014Not Determined
21584850Create StudyPredictive and concurrent validity of parent concern about young children at risk for autism.Journal of autism and developmental disordersHess CR, Landa RJApril 2012Not Determined
21522181Create StudyGene-ontology enrichment analysis in two independent family-based samples highlights biologically plausible processes for autism spectrum disorders.European journal of human genetics : EJHGAnney, Richard J L; Kenny, Elaine M; O'Dushlaine, Colm; Yaspan, Brian L; Parkhomenka, Elena; Buxbaum, Joseph D; Sutcliffe, James; Gill, Michael; Gallagher, Louise; Autism Genome Project; Buxbaum, Joseph D; Sutcliffe, James; Gill, Michael; Gallagher, LouiseOctober 2011Not Determined
21519953Create StudySelective visual attention at twelve months: signs of autism in early social interactions.Journal of autism and developmental disordersHutman T, Chela MK, Gillespie-Lynch K, Sigman MApril 2012Not Determined
21484517Create StudyThe effects of face expertise training on the behavioral performance and brain activity of adults with high functioning autism spectrum disorders.Journal of autism and developmental disordersFaja S, Webb SJ, Jones E, Merkle K, Kamara D, Bavaro J, Aylward E, Dawson GFebruary 2012Not Determined
21484201Create StudyNovel method for combined linkage and genome-wide association analysis finds evidence of distinct genetic architecture for two subtypes of autism.Journal of neurodevelopmental disordersVieland, Veronica J; Hallmayer, Joachim; Huang, Yungui; Pagnamenta, Alistair T; Pinto, Dalila; Khan, Hameed; Monaco, Anthony P; Paterson, Andrew D; Scherer, Stephen W; Sutcliffe, James S; Szatmari, Peter; Autism Genome Project (AGP)June 2011Not Determined
21448237Create StudyReduced transcript expression of genes affected by inherited and de novo CNVs in autism.European journal of human genetics : EJHGNord, Alex S; Roeb, Wendy; Dickel, Diane E; Walsh, Tom; Kusenda, Mary; O'Connor, Kristen Lewis; Malhotra, Dheeraj; McCarthy, Shane E; Stray, Sunday M; Taylor, Susan M; Sebat, Jonathan; STAART Psychopharmacology Network; King, Bryan; King, Mary-Claire; McClellan, Jon MJune 2011Not Determined
21442361Create StudyThe effect of an autism-associated polymorphism in the STK39 gene on the autism symptom domains.Journal of autism and developmental disordersVavolizza, Rick D; Schmeidler, James; Ramoz, Nicolas; Buxbaum, Joseph D; Smith, Christopher J; Silverman, Jeremy MFebruary 2012Not Determined
21438139Create StudyMutations in the TSGA14 gene in families with autism spectrum disorders.American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric GeneticsKorvatska, O; Estes, A; Munson, J; Dawson, G; Bekris, L M; Kohen, R; Yu, C-E; Schellenberg, G D; Raskind, W HApril 2011Not Determined
21404085Create StudyProton magnetic resonance spectroscopy and MRI reveal no evidence for brain mitochondrial dysfunction in children with autism spectrum disorder.Journal of autism and developmental disordersCorrigan, Neva M; Shaw, Dennis W W; Richards, Todd L; Estes, Annette M; Friedman, Seth D; Petropoulos, Helen; Artru, Alan A; Dager, Stephen RJanuary 2012Not Determined
21390918Create StudyImpaired Consonant Trigrams Test (CTT) performance relates to everyday working memory difficulties in children with autism spectrum disorders.Child neuropsychology : a journal on normal and abnormal development in childhood and adolescenceYerys BE, Wallace GL, Jankowski KF, Bollich A, Kenworthy L2011Not Determined
21360830Create StudyAltered posterior cingulate cortical cyctoarchitecture, but normal density of neurons and interneurons in the posterior cingulate cortex and fusiform gyrus in autism.Autism research : official journal of the International Society for Autism ResearchOblak AL, Rosene DL, Kemper TL, Bauman ML, Blatt GJJune 2011Not Determined
21126245Create StudyIntervention targeting development of socially synchronous engagement in toddlers with autism spectrum disorder: a randomized controlled trial.Journal of child psychology and psychiatry, and allied disciplinesLanda, Rebecca J; Holman, Katherine C; O'Neill, Allison H; Stuart, Elizabeth AJanuary 2011Not Determined
21042871Create StudyDiscrepancies between academic achievement and intellectual ability in higher-functioning school-aged children with autism spectrum disorder.Journal of autism and developmental disordersEstes, Annette; Rivera, Vanessa; Bryan, Matthew; Cali, Philip; Dawson, GeraldineAugust 2011Not Determined
21041620Create StudyLaterobasal amygdalar enlargement in 6- to 7-year-old children with autism spectrum disorder.Archives of general psychiatryKim, Jieun E; Lyoo, In Kyoon; Estes, Annette M; Renshaw, Perry F; Shaw, Dennis W; Friedman, Seth D; Kim, Dajung J; Yoon, Sujung J; Hwang, Jaeuk; Dager, Stephen RNovember 2010Not Determined
20860756Create StudyMothers' reports of play dates and observation of school playground behavior of children having high-functioning autism spectrum disorders.Journal of child psychology and psychiatry, and allied disciplinesFrankel FD, Gorospe CM, Chang YC, Sugar CAMay 2011Not Determined
20858465Create StudyReduced GABAA receptors and benzodiazepine binding sites in the posterior cingulate cortex and fusiform gyrus in autism.Brain researchOblak, Adrian L; Gibbs, Terrell T; Blatt, Gene JMarch 22, 2011Not Determined
20676748Create StudySocial networks and friendships at school: comparing children with and without ASD.Journal of autism and developmental disordersKasari, Connie; Locke, Jill; Gulsrud, Amanda; Rotheram-Fuller, ErinMay 2011Not Determined
20673234Create StudySocial involvement of children with autism spectrum disorders in elementary school classrooms.Journal of child psychology and psychiatry, and allied disciplinesRotheram-Fuller E, Kasari C, Chamberlain B, Locke JNovember 2010Not Determined
20663923Create StudyA genome-wide scan for common alleles affecting risk for autism.Human molecular geneticsAnney, Richard; Klei, Lambertus; Pinto, Dalila; Regan, Regina; Conroy, Judith; Magalhaes, Tiago R; Correia, Catarina; Abrahams, Brett S; Sykes, Nuala; Pagnamenta, Alistair T; Almeida, Joana; Bacchelli, Elena; Bailey, Anthony J; Baird, Gillian; Battaglia, Agatino; Berney, Tom; Bolshakova, Nadia; Bölte, Sven; Bolton, Patrick F; Bourgeron, Thomas; Brennan, Sean; Brian, Jessica; Carson, Andrew R; Casallo, Guillermo; Casey, Jillian; Chu, Su H; Cochrane, Lynne; Corsello, Christina; Crawford, Emily L; Crossett, Andrew; Dawson, Geraldine; de Jonge, Maretha; Delorme, Richard; Drmic, Irene; Duketis, Eftichia; Duque, Frederico; Estes, Annette; Farrar, Penny; Fernandez, Bridget A; Folstein, Susan E; Fombonne, Eric; Freitag, Christine M; Gilbert, John; Gillberg, Christopher; Glessner, Joseph T; Goldberg, Jeremy; Green, Jonathan; Guter, Stephen J; Hakonarson, Hakon; Heron, Elizabeth A; Hill, Matthew; Holt, Richard; Howe, Jennifer L; Hughes, Gillian; Hus, Vanessa; Igliozzi, Roberta; Kim, Cecilia; Klauck, Sabine M; Kolevzon, Alexander; Korvatska, Olena; Kustanovich, Vlad; Lajonchere, Clara M; Lamb, Janine A; Laskawiec, Magdalena; Leboyer, Marion; Le Couteur, Ann; Leventhal, Bennett L; Lionel, Anath C; Liu, Xiao-Qing; Lord, Catherine; Lotspeich, Linda; Lund, Sabata C; Maestrini, Elena; Mahoney, William; Mantoulan, Carine; Marshall, Christian R; McConachie, Helen; McDougle, Christopher J; McGrath, Jane; McMahon, William M; Melhem, Nadine M; Merikangas, Alison; Migita, Ohsuke; Minshew, Nancy J; Mirza, Ghazala K; Munson, Jeff; Nelson, Stanley F; Noakes, Carolyn; Noor, Abdul; Nygren, Gudrun; Oliveira, Guiomar; Papanikolaou, Katerina; Parr, Jeremy R; Parrini, Barbara; Paton, Tara; Pickles, Andrew; Piven, Joseph; Posey, David J; Poustka, Annemarie; Poustka, Fritz; Prasad, Aparna; Ragoussis, Jiannis; Renshaw, Katy; Rickaby, Jessica; Roberts, Wendy; Roeder, Kathryn; Roge, Bernadette; Rutter, Michael L; Bierut, Laura J; Rice, John P; Salt, Jeff; Sansom, Katherine; Sato, Daisuke; Segurado, Ricardo; Senman, Lili; Shah, Naisha; Sheffield, Val C; Soorya, Latha; Sousa, Inês; Stoppioni, Vera; Strawbridge, Christina; Tancredi, Raffaella; Tansey, Katherine; Thiruvahindrapduram, Bhooma; Thompson, Ann P; Thomson, Susanne; Tryfon, Ana; Tsiantis, John; Van Engeland, Herman; Vincent, John B; Volkmar, Fred; Wallace, Simon; Wang, Kai; Wang, Zhouzhi; Wassink, Thomas H; Wing, Kirsty; Wittemeyer, Kerstin; Wood, Shawn; Yaspan, Brian L; Zurawiecki, Danielle; Zwaigenbaum, Lonnie; Betancur, Catalina; Buxbaum, Joseph D; Cantor, Rita M; Cook, Edwin H; Coon, Hilary; Cuccaro, Michael L; Gallagher, Louise; Geschwind, Daniel H; Gill, Michael; Haines, Jonathan L; Miller, Judith; Monaco, Anthony P; Nurnberger Jr, John I; Paterson, Andrew D; Pericak-Vance, Margaret A; Schellenberg, Gerard D; Scherer, Stephen W; Sutcliffe, James S; Szatmari, Peter; Vicente, Astrid M; Vieland, Veronica J; Wijsman, Ellen M; Devlin, Bernie; Ennis, Sean; Hallmayer, JoachimOctober 15, 2010Not Determined
20656041Create StudyfMRI evidence of neural abnormalities in the subcortical face processing system in ASD.NeuroImageKleinhans NM, Richards T, Johnson LC, Weaver KE, Greenson J, Dawson G, Aylward EJanuary 1, 2011Not Determined
20655320Create StudyAssociation between amygdala response to emotional faces and social anxiety in autism spectrum disorders.NeuropsychologiaKleinhans, Natalia M; Richards, Todd; Weaver, Kurt; Johnson, L Clark; Greenson, Jessica; Dawson, Geraldine; Aylward, ElizabethOctober 2010Not Determined
20617101Create StudyBehavioral Approaches to Training Developmentally Disabled Children for an Overnight EEG Procedure.Journal of developmental and physical disabilitiesDemore, Melissa; Cataldo, Marilyn; Tierney, Elaine; Slifer, KeithJune 2009Not Determined
20568002Create StudyBehavioral profiles of affected and unaffected siblings of children with autism: contribution of measures of mother-infant interaction and nonverbal communication.Journal of autism and developmental disordersRozga, Agata; Hutman, Ted; Young, Gregory S; Rogers, Sally J; Ozonoff, Sally; Dapretto, Mirella; Sigman, MarianMarch 2011Not Determined
20557420Create StudyDecreased GABA(B) receptors in the cingulate cortex and fusiform gyrus in autism.Journal of neurochemistryOblak AL, Gibbs TT, Blatt GJSeptember 1, 2010Not Determined
20546081Create StudyResponse to distress in infants at risk for autism: a prospective longitudinal study.Journal of child psychology and psychiatry, and allied disciplinesHutman, Ted; Rozga, Agata; DeLaurentis, Angeline D; Barnwell, Jenna M; Sugar, Catherine A; Sigman, MarianSeptember 2010Not Determined
20546079Create StudyCan family affectedness inform infant sibling outcomes of autism spectrum disorders?Journal of child psychology and psychiatry, and allied disciplinesSchwichtenberg, A J; Young, G S; Sigman, M; Hutman, T; Ozonoff, SSeptember 2010Not Determined
20531469Create StudyFunctional impact of global rare copy number variation in autism spectrum disorders.NaturePinto, Dalila; Pagnamenta, Alistair T; Klei, Lambertus; Anney, Richard; Merico, Daniele; Regan, Regina; Conroy, Judith; Magalhaes, Tiago R; Correia, Catarina; Abrahams, Brett S; Almeida, Joana; Bacchelli, Elena; Bader, Gary D; Bailey, Anthony J; Baird, Gillian; Battaglia, Agatino; Berney, Tom; Bolshakova, Nadia; Bölte, Sven; Bolton, Patrick F; Bourgeron, Thomas; Brennan, Sean; Brian, Jessica; Bryson, Susan E; Carson, Andrew R; Casallo, Guillermo; Casey, Jillian; Chung, Brian H Y; Cochrane, Lynne; Corsello, Christina; Crawford, Emily L; Crossett, Andrew; Cytrynbaum, Cheryl; Dawson, Geraldine; de Jonge, Maretha; Delorme, Richard; Drmic, Irene; Duketis, Eftichia; Duque, Frederico; Estes, Annette; Farrar, Penny; Fernandez, Bridget A; Folstein, Susan E; Fombonne, Eric; Freitag, Christine M; Gilbert, John; Gillberg, Christopher; Glessner, Joseph T; Goldberg, Jeremy; Green, Andrew; Green, Jonathan; Guter, Stephen J; Hakonarson, Hakon; Heron, Elizabeth A; Hill, Matthew; Holt, Richard; Howe, Jennifer L; Hughes, Gillian; Hus, Vanessa; Igliozzi, Roberta; Kim, Cecilia; Klauck, Sabine M; Kolevzon, Alexander; Korvatska, Olena; Kustanovich, Vlad; Lajonchere, Clara M; Lamb, Janine A; Laskawiec, Magdalena; Leboyer, Marion; Le Couteur, Ann; Leventhal, Bennett L; Lionel, Anath C; Liu, Xiao-Qing; Lord, Catherine; Lotspeich, Linda; Lund, Sabata C; Maestrini, Elena; Mahoney, William; Mantoulan, Carine; Marshall, Christian R; McConachie, Helen; McDougle, Christopher J; McGrath, Jane; McMahon, William M; Merikangas, Alison; Migita, Ohsuke; Minshew, Nancy J; Mirza, Ghazala K; Munson, Jeff; Nelson, Stanley F; Noakes, Carolyn; Noor, Abdul; Nygren, Gudrun; Oliveira, Guiomar; Papanikolaou, Katerina; Parr, Jeremy R; Parrini, Barbara; Paton, Tara; Pickles, Andrew; Pilorge, Marion; Piven, Joseph; Ponting, Chris P; Posey, David J; Poustka, Annemarie; Poustka, Fritz; Prasad, Aparna; Ragoussis, Jiannis; Renshaw, Katy; Rickaby, Jessica; Roberts, Wendy; Roeder, Kathryn; Roge, Bernadette; Rutter, Michael L; Bierut, Laura J; Rice, John P; Salt, Jeff; Sansom, Katherine; Sato, Daisuke; Segurado, Ricardo; Sequeira, Ana F; Senman, Lili; Shah, Naisha; Sheffield, Val C; Soorya, Latha; Sousa, Inês; Stein, Olaf; Sykes, Nuala; Stoppioni, Vera; Strawbridge, Christina; Tancredi, Raffaella; Tansey, Katherine; Thiruvahindrapduram, Bhooma; Thompson, Ann P; Thomson, Susanne; Tryfon, Ana; Tsiantis, John; Van Engeland, Herman; Vincent, John B; Volkmar, Fred; Wallace, Simon; Wang, Kai; Wang, Zhouzhi; Wassink, Thomas H; Webber, Caleb; Weksberg, Rosanna; Wing, Kirsty; Wittemeyer, Kerstin; Wood, Shawn; Wu, Jing; Yaspan, Brian L; Zurawiecki, Danielle; Zwaigenbaum, Lonnie; Buxbaum, Joseph D; Cantor, Rita M; Cook, Edwin H; Coon, Hilary; Cuccaro, Michael L; Devlin, Bernie; Ennis, Sean; Gallagher, Louise; Geschwind, Daniel H; Gill, Michael; Haines, Jonathan L; Hallmayer, Joachim; Miller, Judith; Monaco, Anthony P; Nurnberger Jr, John I; Paterson, Andrew D; Pericak-Vance, Margaret A; Schellenberg, Gerard D; Szatmari, Peter; Vicente, Astrid M; Vieland, Veronica J; Wijsman, Ellen M; Scherer, Stephen W; Sutcliffe, James S; Betancur, CatalinaJuly 15, 2010Not Determined
20456532Create StudySocial and non-social visual attention patterns and associative learning in infants at risk for autism.Journal of child psychology and psychiatry, and allied disciplinesBhat AN, Galloway JC, Landa RJSeptember 2010Not Determined
20452382Create StudyResponse to familiar faces, newly familiar faces, and novel faces as assessed by ERPs is intact in adults with autism spectrum disorders.International journal of psychophysiology : official journal of the International Organization of PsychophysiologyWebb, Sara J; Jones, Emily J H; Merkle, Kristen; Murias, Michael; Greenson, Jessica; Richards, Todd; Aylward, Elizabeth; Dawson, GeraldineAugust 2010Not Determined
20410715Create StudyA prospective study of the emergence of early behavioral signs of autism.Journal of the American Academy of Child and Adolescent PsychiatryOzonoff S, Iosif AM, Baguio F, Cook IC, Hill MM, Hutman T, Rogers SJ, Rozga A, Sangha S, Sigman M, Steinfeld MB, Young GSMarch 2010Not Determined
20394055Create StudyLanguage-related Cntnap2 gene is differentially expressed in sexually dimorphic song nuclei essential for vocal learning in songbirds.The Journal of comparative neurologyPanaitof, S Carmen; Abrahams, Brett S; Dong, Hongmei; Geschwind, Daniel H; White, Stephanie AJune 1, 2010Not Determined
20385903Create StudyConnecting genes to brain in the autism spectrum disorders.Archives of neurologyAbrahams, Brett S; Geschwind, Daniel HApril 2010Not Determined
20356575Create StudySpeech-and-gesture integration in high functioning autism.CognitionSilverman, Laura B; Bennetto, Loisa; Campana, Ellen; Tanenhaus, Michael KJune 2010Not Determined
20301009Create StudyToddlers with elevated autism symptoms show slowed habituation to faces.Child neuropsychology : a journal on normal and abnormal development in childhood and adolescenceWebb, Sara Jane; Jones, Emily J H; Merkle, Kristen; Namkung, Jessica; Toth, Karen; Greenson, Jessica; Murias, Michael; Dawson, Geraldine2010Not Determined
20112084Create StudyPlay and developmental outcomes in infant siblings of children with autism.Journal of autism and developmental disordersChristensen, Lisa; Hutman, Ted; Rozga, Agata; Young, Gregory S; Ozonoff, Sally; Rogers, Sally J; Baker, Bruce; Sigman, MarianAugust 2010Not Determined
20058059Create StudyA randomized controlled study of parent-assisted Children''s Friendship Training with children having autism spectrum disorders.Journal of autism and developmental disordersFrankel, Fred; Myatt, Robert; Sugar, Catherine; Whitham, Cynthia; Gorospe, Clarissa M; Laugeson, ElizabethJuly 2010Not Determined
20044143Create StudyRelationship between whole blood serotonin and repetitive behaviors in autism.Psychiatry researchKolevzon A, Newcorn JH, Kryzak L, Chaplin W, Watner D, Hollander E, Smith CJ, Cook EH, Silverman JMFebruary 28, 2010Not Determined
20015484Create StudySlc25a12 disruption alters myelination and neurofilaments: a model for a hypomyelination syndrome and childhood neurodevelopmental disorders.Biological psychiatrySakurai, Takeshi; Ramoz, Nicolas; Barreto, Marta; Gazdoiu, Mihaela; Takahashi, Nagahide; Gertner, Michael; Dorr, Nathan; Gama Sosa, Miguel A; De Gasperi, Rita; Perez, Gissel; Schmeidler, James; Mitropoulou, Vivian; Le, H Carl; Lupu, Mihaela; Hof, Patrick R; Elder, Gregory A; Buxbaum, Joseph DMay 1, 2010Not Determined
19998356Create StudyAttention deficit/hyperactivity disorder symptoms moderate cognition and behavior in children with autism spectrum disorders.Autism research : official journal of the International Society for Autism ResearchYerys, Benjamin E; Wallace, Gregory L; Sokoloff, Jennifer L; Shook, Devon A; James, Joette D; Kenworthy, LaurenDecember 2009Not Determined
19948568Create StudyRandomized, controlled trial of an intervention for toddlers with autism: the Early Start Denver Model.PediatricsDawson, Geraldine; Rogers, Sally; Munson, Jeffrey; Smith, Milani; Winter, Jamie; Greenson, Jessica; Donaldson, Amy; Varley, JenniferJanuary 2010Not Determined
19827218Create StudyHow early do parent concerns predict later autism diagnosis?Journal of developmental and behavioral pediatrics : JDBPOzonoff, Sally; Young, Gregory S; Steinfeld, Mary Beth; Hill, Monique M; Cook, Ian; Hutman, Ted; Macari, Suzanne; Rogers, Sally J; Sigman, MarianOctober 2009Not Determined
19816954Create StudyStability and individual change in depressive symptoms among mothers raising young children with ASD: maternal and child correlates.Journal of clinical psychologyCarter, Alice S; Martínez-Pedraza, Frances de L; Gray, Sarah A ODecember 2009Not Determined
19759065Create StudySet-shifting in children with autism spectrum disorders: reversal shifting deficits on the Intradimensional/Extradimensional Shift Test correlate with repetitive behaviors.Autism : the international journal of research and practiceYerys, Benjamin E; Wallace, Gregory L; Harrison, Bryan; Celano, Mark J; Giedd, Jay N; Kenworthy, Lauren ESeptember 2009Not Determined
19726642Create StudyA neuroligin-4 missense mutation associated with autism impairs neuroligin-4 folding and endoplasmic reticulum export.The Journal of neuroscience : the official journal of the Society for NeuroscienceZhang, Chen; Milunsky, Jeff M; Newton, Stephanie; Ko, Jaewon; Zhao, Geping; Maher, Tom A; Tager-Flusberg, Helen; Bolliger, Marc F; Carter, Alice S; Boucard, Antony A; Powell, Craig M; Südhof, Thomas CSeptember 2, 2009Not Determined
19650112Create StudyDecreased GABAA receptors and benzodiazepine binding sites in the anterior cingulate cortex in autism.Autism research : official journal of the International Society for Autism ResearchOblak, A; Gibbs, T T; Blatt, G JAugust 2009Not Determined
19590881Create StudyThe anterior cingulate cortex in autism: heterogeneity of qualitative and quantitative cytoarchitectonic features suggests possible subgroups.Acta neuropathologicaSimms ML, Kemper TL, Timbie CM, Bauman ML, Blatt GJNovember 2009Not Determined
19582564Create StudyDissemination of evidence-based practice: can we train therapists from a distance?Journal of autism and developmental disordersVismara, Laurie A; Young, Gregory S; Stahmer, Aubyn C; Griffith, Elizabeth McMahon; Rogers, Sally JDecember 2009Not Determined
19572193Create StudyBrief report: IQ split predicts social symptoms and communication abilities in high-functioning children with autism spectrum disorders.Journal of autism and developmental disordersBlack, David O; Wallace, Gregory L; Sokoloff, Jennifer L; Kenworthy, LaurenNovember 2009Not Determined
19559060Create StudyMethamphetamine treatment causes delayed decrease in novelty-induced locomotor activity in mice.Neuroscience researchKrasnova, Irina N; Hodges, Amber B; Ladenheim, Bruce; Rhoades, Raina; Phillip, Crystal G; Cesena, Angela; Ivanova, Ekaterina; Hohmann, Christine F; Cadet, Jean LudOctober 2009Not Determined
19487623Create StudyLack of efficacy of citalopram in children with autism spectrum disorders and high levels of repetitive behavior: citalopram ineffective in children with autism.Archives of general psychiatryKing, Bryan H; Hollander, Eric; Sikich, Linmarie; McCracken, James T; Scahill, Lawrence; Bregman, Joel D; Donnelly, Craig L; Anagnostou, Evdokia; Dukes, Kimberly; Sullivan, Lisa; Hirtz, Deborah; Wagner, Ann; Ritz, Louise; STAART Psychopharmacology NetworkJune 2009Not Determined
19454620Create StudyERP responses differentiate inverted but not upright face processing in adults with ASD.Social cognitive and affective neuroscienceWebb, Sara Jane; Merkle, Kristen; Murias, Michael; Richards, Todd; Aylward, Elizabeth; Dawson, GeraldineJune 2012Not Determined
19452267Create StudyBrief report: parental age and the sex ratio in autism.Journal of autism and developmental disordersAnello, Alene; Reichenberg, Abraham; Luo, Xiaodong; Schmeidler, James; Hollander, Eric; Smith, Christopher J; Puleo, Connor M; Kryzak, Lauren A; Silverman, Jeremy MOctober 2009Not Determined
19432386Create StudyMultiple rare variants in the etiology of autism spectrum disorders.Dialogues in clinical neuroscienceBuxbaum JD2009Not Determined
19404257Create StudyAutism genome-wide copy number variation reveals ubiquitin and neuronal genes.NatureGlessner, Joseph T; Wang, Kai; Cai, Guiqing; Korvatska, Olena; Kim, Cecilia E; Wood, Shawn; Zhang, Haitao; Estes, Annette; Brune, Camille W; Bradfield, Jonathan P; Imielinski, Marcin; Frackelton, Edward C; Reichert, Jennifer; Crawford, Emily L; Munson, Jeffrey; Sleiman, Patrick M A; Chiavacci, Rosetta; Annaiah, Kiran; Thomas, Kelly; Hou, Cuiping; Glaberson, Wendy; Flory, James; Otieno, Frederick; Garris, Maria; Soorya, Latha; Klei, Lambertus; Piven, Joseph; Meyer, Kacie J; Anagnostou, Evdokia; Sakurai, Takeshi; Game, Rachel M; Rudd, Danielle S; Zurawiecki, Danielle; McDougle, Christopher J; Davis, Lea K; Miller, Judith; Posey, David J; Michaels, Shana; Kolevzon, Alexander; Silverman, Jeremy M; Bernier, Raphael; Levy, Susan E; Schultz, Robert T; Dawson, Geraldine; Owley, Thomas; McMahon, William M; Wassink, Thomas H; Sweeney, John A; Nurnberger, John I; Coon, Hilary; Sutcliffe, James S; Minshew, Nancy J; Grant, Struan F A; Bucan, Maja; Cook, Edwin H; Buxbaum, Joseph D; Devlin, Bernie; Schellenberg, Gerard D; Hakonarson, HakonMay 28, 2009Not Determined
19404256Create StudyCommon genetic variants on 5p14.1 associate with autism spectrum disorders.NatureWang, Kai; Zhang, Haitao; Ma, Deqiong; Bucan, Maja; Glessner, Joseph T; Abrahams, Brett S; Salyakina, Daria; Imielinski, Marcin; Bradfield, Jonathan P; Sleiman, Patrick M A; Kim, Cecilia E; Hou, Cuiping; Frackelton, Edward; Chiavacci, Rosetta; Takahashi, Nagahide; Sakurai, Takeshi; Rappaport, Eric; Lajonchere, Clara M; Munson, Jeffrey; Estes, Annette; Korvatska, Olena; Piven, Joseph; Sonnenblick, Lisa I; Alvarez Retuerto, Ana I; Herman, Edward I; Dong, Hongmei; Hutman, Ted; Sigman, Marian; Ozonoff, Sally; Klin, Ami; Owley, Thomas; Sweeney, John A; Brune, Camille W; Cantor, Rita M; Bernier, Raphael; Gilbert, John R; Cuccaro, Michael L; McMahon, William M; Miller, Judith; State, Matthew W; Wassink, Thomas H; Coon, Hilary; Levy, Susan E; Schultz, Robert T; Nurnberger, John I; Haines, Jonathan L; Sutcliffe, James S; Cook, Edwin H; Minshew, Nancy J; Buxbaum, Joseph D; Dawson, Geraldine; Grant, Struan F A; Geschwind, Daniel H; Pericak-Vance, Margaret A; Schellenberg, Gerard D; Hakonarson, HakonMay 28, 2009Not Determined
19384887Create StudyThe fMRI success rate of children and adolescents: typical development, epilepsy, attention deficit/hyperactivity disorder, and autism spectrum disorders.Human brain mappingYerys BE, Jankowski KF, Shook D, Rosenberger LR, Barnes KA, Berl MM, Ritzl EK, Vanmeter J, Vaidya CJ, Gaillard WDOctober 2009Not Determined
19363431Create StudyResearch applications of magnetic resonance spectroscopy to investigate psychiatric disorders.Topics in magnetic resonance imaging : TMRIDager, Stephen R; Corrigan, Neva M; Richards, Todd L; Posse, StefanApril 2008Not Determined
19360675Create StudyA large-scale screen for coding variants in SERT/SLC6A4 in autism spectrum disorders.Autism research : official journal of the International Society for Autism ResearchSakurai, Takeshi; Reichert, Jennifer; Hoffman, Ellen J; Cai, Guiqing; Jones, Hywel B; Faham, Malek; Buxbaum, Joseph DAugust 2008Not Determined
19360673Create StudyBrain function and gaze fixation during facial-emotion processing in fragile X and autism.Autism research : official journal of the International Society for Autism ResearchDalton, Kim M; Holsen, Laura; Abbeduto, Leonard; Davidson, Richard JAugust 2008Not Determined
19322649Create StudyAn investigation of the relationship between fMRI and ERP source localized measurements of brain activity during face processing.Brain topographyCorrigan, Neva M; Richards, Todd; Webb, Sara Jane; Murias, Michael; Merkle, Kristen; Kleinhans, Natalia M; Johnson, L Clark; Poliakov, Andrew; Aylward, Elizabeth; Dawson, GeraldineSeptember 2009Not Determined
19306385Create StudyCardiovascular safety of medication treatments for attention-deficit/hyperactivity disorder.The Mount Sinai journal of medicine, New YorkNewcorn JH, Donnelly CApril 2009Not Relevant
19263208Create StudyConfirmatory factor analysis of the child behavior checklist 1.5-5 in a sample of children with autism spectrum disorders.Journal of autism and developmental disordersPandolfi, Vincent; Magyar, Caroline I; Dill, Charles AJuly 2009Not Determined
19243924Create StudyCerebellar vermal volumes and behavioral correlates in children with autism spectrum disorder.Psychiatry researchWebb, Sara Jane; Sparks, Bobbi-Faun; Friedman, Seth D; Shaw, Dennis W W; Giedd, Jay; Dawson, Geraldine; Dager, Stephen RApril 30, 2009Not Determined
19234776Create StudyBrief report: biochemical correlates of clinical impairment in high functioning autism and Asperger''s disorder.Journal of autism and developmental disordersKleinhans, Natalia M; Richards, Todd; Weaver, Kurt E; Liang, Olivia; Dawson, Geraldine; Aylward, ElizabethJuly 2009Not Determined
19223437Create StudyReduced neural habituation in the amygdala and social impairments in autism spectrum disorders.The American journal of psychiatryKleinhans, Natalia M; Johnson, L Clark; Richards, Todd; Mahurin, Roderick; Greenson, Jessica; Dawson, Geraldine; Aylward, ElizabethApril 2009Not Determined
19151711Create StudyLaminar and compartmental regulation of dendritic growth in mature cortex.Nature neuroscienceChow, David K; Groszer, Matthias; Pribadi, Mochtar; Machniki, Michal; Carmichael, S Thomas; Liu, Xin; Trachtenberg, Joshua TFebruary 2009Not Determined
19127655Create StudyEvidence for latent classes of IQ in young children with autism spectrum disorder.American journal of mental retardation : AJMRMunson, Jeffrey; Dawson, Geraldine; Sterling, Lindsey; Beauchaine, Theodore; Zhou, Andrew; Elizabeth, Koehler; Lord, Catherine; Rogers, Sally; Sigman, Marian; Estes, Annette; Abbott, RobertNovember 2008Not Determined
19111285Create StudyReference production in young speakers with and without autism: effects of discourse status and processing constraints.CognitionArnold, Jennifer E; Bennetto, Loisa; Diehl, Joshua JFebruary 2009Not Determined
19068486Create StudyFunctional connectivity of the inferior frontal cortex changes with age in children with autism spectrum disorders: a fcMRI study of response inhibition.Cerebral cortex (New York, N.Y. : 1991)Lee, Philip S; Yerys, Benjamin E; Della Rosa, Anne; Foss-Feig, Jennifer; Barnes, Kelly Anne; James, Joette D; VanMeter, John; Vaidya, Chandan J; Gaillard, William D; Kenworthy, Lauren EAugust 2009Not Determined
19033154Create StudyDrosophila vesicular monoamine transporter mutants can adapt to reduced or eliminated vesicular stores of dopamine and serotonin.GeneticsSimon, Anne F; Daniels, Richard; Romero-Calderón, Rafael; Grygoruk, Anna; Chang, Hui-Yun; Najibi, Rod; Shamouelian, David; Salazar, Evelyn; Solomon, Mordecai; Ackerson, Larry C; Maidment, Nigel T; Diantonio, Aaron; Krantz, David EFebruary 2009Not Determined
19015968Create StudyParent-assisted social skills training to improve friendships in teens with autism spectrum disorders.Journal of autism and developmental disordersLaugeson, Elizabeth A; Frankel, Fred; Mogil, Catherine; Dillon, Ashley RApril 2009Not Determined
19003497Create StudyThe influences of task difficulty and response correctness on neural systems supporting fluid reasoning.Cognitive neurodynamicsKalbfleisch, M Layne; Van Meter, John W; Zeffiro, Thomas AMarch 2007Not Determined
18999331Create StudyModeling longitudinal change in the language abilities of children with autism: parent behaviors and child characteristics as predictors of change.Developmental psychologySiller M, Sigman MNovember 2008Not Determined
18985104Create StudyModel syndromes for investigating social cognitive and affective neuroscience: a comparison of Autism and Williams syndrome.Social cognitive and affective neuroscienceTager-Flusberg, Helen; Skwerer, Daniela Plesa; Joseph, Robert MDecember 2006Not Relevant
18984147Create StudyAutism: many genes, common pathways?CellGeschwind, Daniel HOctober 31, 2008Not Determined
18954476Create StudyNeurocognitive predictors of social and communicative developmental trajectories in preschoolers with autism spectrum disorders.Journal of the International Neuropsychological Society : JINSMunson, Jeffrey; Faja, Susan; Meltzoff, Andrew; Abbott, Robert; Dawson, GeraldineNovember 2008Not Determined
18782849Create StudyAssociation of common variants in the Joubert syndrome gene (AHI1) with autism.Human molecular geneticsAlvarez Retuerto, Ana I; Cantor, Rita M; Gleeson, Joseph G; Ustaszewska, Anna; Schackwitz, Wendy S; Pennacchio, Len A; Geschwind, Daniel HDecember 15, 2008Not Determined
18751880Create StudyBrief report: face configuration accuracy and processing speed among adults with high-functioning autism spectrum disorders.Journal of autism and developmental disordersFaja, Susan; Webb, Sara Jane; Merkle, Kristen; Aylward, Elizabeth; Dawson, GeraldineMarch 2009Not Determined
18655901Create StudyOxytocin and experimental therapeutics in autism spectrum disorders.Progress in brain researchBartz JA, Hollander E2008Not Determined
18632090Create StudyGenome-wide linkage analyses of quantitative and categorical autism subphenotypes.Biological psychiatryLiu, Xiao-Qing; Paterson, Andrew D; Szatmari, Peter; Autism Genome Project ConsortiumOctober 2008Not Determined
18606031Create StudyEarly behavioral intervention, brain plasticity, and the prevention of autism spectrum disorder.Development and psychopathologyDawson G2008Not Determined
18502497Create StudyResolving ambiguity: a psycholinguistic approach to understanding prosody processing in high-functioning autism.Brain and languageDiehl, Joshua J; Bennetto, Loisa; Watson, Duane; Gunlogson, Christine; McDonough, JoyceAugust 2008Not Determined
18498344Create StudySensory clusters of toddlers with autism spectrum disorders: differences in affective symptoms.Journal of child psychology and psychiatry, and allied disciplinesBen-Sasson A, Cermak SA, Orsmond GI, Tager-Flusberg H, Kadlec MB, Carter ASAugust 2008Not Determined
18463237Create StudyDiffusion tensor imaging of cortical surface development.The Journal of neuroscience : the official journal of the Society for NeuroscienceHutchinson EB, Kelley DJMay 7, 2008Not Relevant
18443967Create StudyBecoming a face expert: a computerized face-training program for high-functioning individuals with autism spectrum disorders.Developmental neuropsychologyFaja S, Aylward E, Bernier R, Dawson G2008Not Determined
18439113Create StudyPsychopharmacology of aggression in children and adolescents with autism: a critical review of efficacy and tolerability.Journal of child and adolescent psychopharmacologyParikh MS, Kolevzon A, Hollander EApril 2008Not Determined
18414403Create StudyAdvances in autism genetics: on the threshold of a new neurobiology.Nature reviews. GeneticsAbrahams, Brett S; Geschwind, Daniel HMay 2008Not Determined
18348195Create StudyAn analysis of candidate autism loci on chromosome 2q24-q33: evidence for association to the STK39 gene.American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric GeneticsRamoz, Nicolas; Cai, Guiqing; Reichert, Jennifer G; Silverman, Jeremy M; Buxbaum, Joseph DOctober 5, 2008Not Determined
18306030Create StudyThe role of face familiarity in eye tracking of faces by individuals with autism spectrum disorders.Journal of autism and developmental disordersSterling, Lindsey; Dawson, Geraldine; Webb, Sara; Murias, Michael; Munson, Jeffrey; Panagiotides, Heracles; Aylward, ElizabethOctober 2008Not Determined
18305076Create StudyAutism spectrum disorders: clinical and research frontiers.Archives of disease in childhoodCaronna EB, Milunsky JM, Tager-Flusberg HJune 2008Not Relevant
18253102Create StudyDiagnosis of autism spectrum disorders in the first 3 years of life.Nature clinical practice. NeurologyLanda RJMarch 2008Not Determined
18240012Create StudyParenting stress in mothers and fathers of toddlers with autism spectrum disorders: associations with child characteristics.Journal of autism and developmental disordersDavis, Naomi Ornstein; Carter, Alice SAugust 2008Not Determined
18234695Create StudyAbnormal functional connectivity in autism spectrum disorders during face processing.Brain : a journal of neurologyKleinhans NM, Richards T, Sterling L, Stegbauer KC, Mahurin R, Johnson LC, Greenson J, Dawson G, Aylward EApril 2008Not Determined
18188685Create StudyLanguage assessment and development in toddlers with autism spectrum disorders.Journal of autism and developmental disordersLuyster, Rhiannon J; Kadlec, Mary Beth; Carter, Alice; Tager-Flusberg, HelenSeptember 2008Not Determined
18058011Create StudyHead circumference as an early predictor of autism symptoms in younger siblings of children with autism spectrum disorder.Journal of autism and developmental disordersElder, Lauren M; Dawson, Geraldine; Toth, Karen; Fein, Deborah; Munson, JeffJuly 2008Not Determined
18001468Create StudyMutation analysis of the NSD1 gene in patients with autism spectrum disorders and macrocephaly.BMC medical geneticsBuxbaum JD, Cai G, Nygren G, Chaste P, Delorme R, Goldsmith J, Råstam M, Silverman JM, Hollander E, Gillberg C, Leboyer M, Betancur C2007Not Determined
17975722Create StudyCharacteristics associated with presence of depressive symptoms in adults with autism spectrum disorder.Journal of autism and developmental disordersSterling, Lindsey; Dawson, Geraldine; Estes, Annette; Greenson, JessicaJuly 2008Not Determined
17974928Create StudySmith-Lemli-Opitz syndrome and autism spectrum disorder.The American journal of psychiatryBukelis I, Porter FD, Zimmerman AW, Tierney ENovember 2007Not Determined
17971879Create StudyCreating physical 3D stereolithograph models of brain and skull.PloS oneKelley DJ, Farhoud M, Meyerand ME, Nelson DL, Ramirez LF, Dempsey RJ, Wolf AJ, Alexander AL, Davidson RJ2007Not Relevant
17963435Create StudyLevel of intellectual functioning predicts patterns of associated symptoms in school-age children with autism spectrum disorder.American journal of mental retardation : AJMREstes AM, Dawson G, Sterling L, Munson JNovember 2007Not Determined
17944296Create StudyExtreme sensory modulation behaviors in toddlers with autism spectrum disorders.The American journal of occupational therapy : official publication of the American Occupational Therapy AssociationBen-Sasson, Ayelet; Cermak, Sharon A; Orsmond, Gael I; Tager-Flusberg, Helen; Carter, Alice S; Kadlec, Mary Beth; Dunn, WinnieSeptember 2007Not Determined
17940244Create StudyRate of head circumference growth as a function of autism diagnosis and history of autistic regression.Journal of child neurologyWebb, Sara Jane; Nalty, Theresa; Munson, Jeff; Brock, Catherine; Abbott, Robert; Dawson, GeraldineOctober 2007Not Determined
17924181Create StudyA comparative analysis of well-being and coping among mothers of toddlers and mothers of adolescents with ASD.Journal of autism and developmental disordersSmith, Leann E; Seltzer, Marsha Mailick; Tager-Flusberg, Helen; Greenberg, Jan S; Carter, Alice SMay 2008Not Determined
17894412Create StudyAutism-related routines and rituals associated with a mitochondrial aspartate/glutamate carrier SLC25A12 polymorphism.American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric GeneticsSilverman, Jeremy M; Buxbaum, Joseph D; Ramoz, Nicolas; Schmeidler, James; Reichenberg, Abraham; Hollander, Eric; Angelo, Gary; Smith, Christopher J; Kryzak, Lauren AApril 5, 2008Not Determined
17716073Create StudyAutism from developmental and neuropsychological perspectives.Annual review of clinical psychologySigman M, Spence SJ, Wang AT2006Not Determined
17683453Create StudyAudiovisual speech integration and lipreading in autism.Journal of child psychology and psychiatry, and allied disciplinesSmith EG, Bennetto LAugust 2007Not Determined
17606819Create StudySocial and communication development in toddlers with early and later diagnosis of autism spectrum disorders.Archives of general psychiatryLanda RJ, Holman KC, Garrett-Mayer EJuly 2007Not Determined
17572391Create StudyOlfaction and taste processing in autism.Biological psychiatryBennetto, Loisa; Kuschner, Emily S; Hyman, Susan LNovember 1, 2007Not Determined
17558282Create StudyIncreased amygdala activation to neutral faces is associated with better face memory performance.NeuroreportKleinhans NM, Johnson LC, Mahurin R, Richards T, Stegbauer KC, Greenson J, Dawson G, Aylward EJuly 2, 2007Not Determined
17548752Create StudyCerebral cortical gray matter overgrowth and functional variation of the serotonin transporter gene in autism.Archives of general psychiatryWassink TH, Hazlett HC, Epping EA, Arndt S, Dager SR, Schellenberg GD, Dawson G, Piven JJune 2007Not Determined
17451856Create StudyEEG mu rhythm and imitation impairments in individuals with autism spectrum disorder.Brain and cognitionBernier, R; Dawson, G; Webb, S; Murias, MAugust 2007Not Determined
17438342Create StudyOutcome for children with autism who began intensive behavioral treatment between ages 4 and 7: a comparison controlled study.Behavior modificationEikeseth S, Smith T, Jahr E, Eldevik SMay 2007Not Determined
17437070Create StudyFactor structure evaluation of the childhood autism rating scale.Journal of autism and developmental disordersMagyar, Caroline I; Pandolfi, VincentOctober 2007Not Determined
17427195Create StudyMutation screening of the PTEN gene in patients with autism spectrum disorders and macrocephaly.American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric GeneticsBuxbaum, Joseph D; Cai, Guiqing; Chaste, Pauline; Nygren, Gudrun; Goldsmith, Juliet; Reichert, Jennifer; Anckarsäter, Henrik; Rastam, Maria; Smith, Christopher J; Silverman, Jeremy M; Hollander, Eric; Leboyer, Marion; Gillberg, Christopher; Verloes, Alain; Betancur, CatalinaJune 5, 2007Not Determined
17426350Create StudyUnobtrusive integration of data management with fMRI analysis.NeuroinformaticsPoliakov, Andrew V; Hertzenberg, Xenia; Moore, Eider B; Corina, David P; Ojemann, George A; Brinkley, James F2007Not Determined
17416819Create StudyShape mapping of the hippocampus in young children with autism spectrum disorder.AJNR. American journal of neuroradiologyDager, S R; Wang, L; Friedman, S D; Shaw, D W; Constantino, J N; Artru, A A; Dawson, G; Csernansky, J GApril 2007Not Relevant
17336944Create StudyResting state cortical connectivity reflected in EEG coherence in individuals with autism.Biological psychiatryMurias, Michael; Webb, Sara J; Greenson, Jessica; Dawson, GeraldineAugust 1, 2007Not Determined
17322880Create StudyMapping autism risk loci using genetic linkage and chromosomal rearrangements.Nature geneticsAutism Genome Project Consortium; Szatmari, Peter; Paterson, Andrew D; Zwaigenbaum, Lonnie; Roberts, Wendy; Brian, Jessica; Liu, Xiao-Qing; Vincent, John B; Skaug, Jennifer L; Thompson, Ann P; Senman, Lili; Feuk, Lars; Qian, Cheng; Bryson, Susan E; Jones, Marshall B; Marshall, Christian R; Scherer, Stephen W; Vieland, Veronica J; Bartlett, Christopher; Mangin, La Vonne; Goedken, Rhinda; Segre, Alberto; Pericak-Vance, Margaret A; Cuccaro, Michael L; Gilbert, John R; Wright, Harry H; Abramson, Ruth K; Betancur, Catalina; Bourgeron, Thomas; Gillberg, Christopher; Leboyer, Marion; Buxbaum, Joseph D; Davis, Kenneth L; Hollander, Eric; Silverman, Jeremy M; Hallmayer, Joachim; Lotspeich, Linda; Sutcliffe, James S; Haines, Jonathan L; Folstein, Susan E; Piven, Joseph; Wassink, Thomas H; Sheffield, Val; Geschwind, Daniel H; Bucan, Maja; Brown, W Ted; Cantor, Rita M; Constantino, John N; Gilliam, T Conrad; Herbert, Martha; Lajonchere, Clara; Ledbetter, David H; Lese-Martin, Christa; Miller, Janet; Nelson, Stan; Samango-Sprouse, Carol A; Spence, Sarah; State, Matthew; Tanzi, Rudolph E; Coon, Hilary; Dawson, Geraldine; Devlin, Bernie; Estes, Annette; Flodman, Pamela; Klei, Lambertus; McMahon, William M; Minshew, Nancy; Munson, Jeff; Korvatska, Elena; Rodier, Patricia M; Schellenberg, Gerard D; Smith, Moyra; Spence, M Anne; Stodgell, Chris; Tepper, Ping Guo; Wijsman, Ellen M; Yu, Chang-En; Rogé, Bernadette; Mantoulan, Carine; Wittemeyer, Kerstin; Poustka, Annemarie; Felder, Bärbel; Klauck, Sabine M; Schuster, Claudia; Poustka, Fritz; Bölte, Sven; Feineis-Matthews, Sabine; Herbrecht, Evelyn; Schmötzer, Gabi; Tsiantis, John; Papanikolaou, Katerina; Maestrini, Elena; Bacchelli, Elena; Blasi, Francesca; Carone, Simona; Toma, Claudio; Van Engeland, Herman; de Jonge, Maretha; Kemner, Chantal; Koop, Frederieke; Koop, Frederike; Langemeijer, Marjolein; Langemeijer, Marjolijn; Hijmans, Channa; Hijimans, Channa; Staal, Wouter G; Baird, Gillian; Bolton, Patrick F; Rutter, Michael L; Weisblatt, Emma; Green, Jonathan; Aldred, Catherine; Wilkinson, Julie-Anne; Pickles, Andrew; Le Couteur, Ann; Berney, Tom; McConachie, Helen; Bailey, Anthony J; Francis, Kostas; Honeyman, Gemma; Hutchinson, Aislinn; Parr, Jeremy R; Wallace, Simon; Monaco, Anthony P; Barnby, Gabrielle; Kobayashi, Kazuhiro; Lamb, Janine A; Sousa, Ines; Sykes, Nuala; Cook, Edwin H; Guter, Stephen J; Leventhal, Bennett L; Salt, Jeff; Lord, Catherine; Corsello, Christina; Hus, Vanessa; Weeks, Daniel E; Volkmar, Fred; Tauber, Maïté; Fombonne, Eric; Shih, Andy; Meyer, Kacie JMarch 2007Not Determined
17296168Create StudyNeonatal serotonin depletion alters behavioral responses to spatial change and novelty.Brain researchHohmann CF, Walker EM, Boylan CB, Blue MEMarch 30, 2007Not Determined
17275283Create StudyAutism spectrum disorders: developmental disconnection syndromes.Current opinion in neurobiologyGeschwind DH, Levitt PFebruary 2007Not Determined
17216333Create StudySex differences in toddlers with autism spectrum disorders.Journal of autism and developmental disordersCarter, Alice S; Black, David O; Tewani, Sonia; Connolly, Christine E; Kadlec, Mary Beth; Tager-Flusberg, HelenJanuary 2007Not Determined
17216332Create StudyResponse to joint attention in toddlers at risk for autism spectrum disorder: a prospective study.Journal of autism and developmental disordersSullivan, Michelle; Finelli, Julianna; Marvin, Alison; Garrett-Mayer, Elizabeth; Bauman, Margaret; Landa, RebeccaJanuary 2007Not Determined
17146016Create StudyAmygdala volume and nonverbal social impairment in adolescent and adult males with autism.Archives of general psychiatryNacewicz BM, Dalton KM, Johnstone T, Long MT, McAuliff EM, Oakes TR, Alexander AL, Davidson RJDecember 2006Not Determined
17137564Create StudyRate of head growth decelerates and symptoms worsen in the second year of life in autism.Biological psychiatryDawson, Geraldine; Munson, Jeff; Webb, Sara Jane; Nalty, Theresa; Abbott, Robert; Toth, KarenFebruary 15, 2007Not Determined
17106428Create StudyAssociation analysis of the NrCAM gene in autism and in subsets of families with severe obsessive-compulsive or self-stimulatory behaviors.Psychiatric geneticsSakurai T, Ramoz N, Reichert JG, Corwin TE, Kryzak L, Smith CJ, Silverman JM, Hollander E, Buxbaum JDDecember 2006Not Determined
17069771Create StudyGaze-fixation, brain activation, and amygdala volume in unaffected siblings of individuals with autism.Biological psychiatryDalton KM, Nacewicz BM, Alexander AL, Davidson RJFebruary 15, 2007Not Determined
17034875Create StudyModeling early cortical serotonergic deficits in autism.Behavioural brain researchBoylan CB, Blue ME, Hohmann CFJanuary 10, 2007Not Determined
16958027Create StudyFamily-based association study of TPH1 and TPH2 polymorphisms in autism.American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric GeneticsRamoz, Nicolas; Cai, Guiqing; Reichert, Jennifer G; Corwin, Thomas E; Kryzak, Lauren A; Smith, Christopher J; Silverman, Jeremy M; Hollander, Eric; Buxbaum, Joseph DDecember 5, 2006Not Determined
16924017Create StudyGray matter abnormalities in autism spectrum disorder revealed by T2 relaxation.NeurologyPetropoulos H, Friedman SD, Shaw DW, Artru AA, Dawson G, Dager SRAugust 22, 2006Not Determined
16904652Create StudyOxytocin increases retention of social cognition in autism.Biological psychiatryHollander E, Bartz J, Chaplin W, Phillips A, Sumner J, Soorya L, Anagnostou E, Wasserman SFebruary 15, 2007Not Determined
16897400Create StudyERP evidence of atypical face processing in young children with autism.Journal of autism and developmental disordersWebb, Sara J; Dawson, Geraldine; Bernier, Raphael; Panagiotides, HeraclesOctober 2006Not Determined
16884725Create StudyThe neuroscience of affiliation: forging links between basic and clinical research on neuropeptides and social behavior.Hormones and behaviorBartz JA, Hollander ENovember 2006Not Determined
16874769Create StudyAbnormalities of cholesterol metabolism in autism spectrum disorders.American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric GeneticsTierney, Elaine; Bukelis, Irena; Thompson, Richard E; Ahmed, Khalid; Aneja, Alka; Kratz, Lisa; Kelley, Richard ISeptember 5, 2006Not Determined
16855874Create StudyInvolvement or isolation? The social networks of children with autism in regular classrooms.Journal of autism and developmental disordersChamberlain, Brandt; Kasari, Connie; Rotheram-Fuller, ErinFebruary 2007Not Determined
16845578Create StudyEarly predictors of communication development in young children with autism spectrum disorder: joint attention, imitation, and toy play.Journal of autism and developmental disordersToth K, Munson J, Meltzoff AN, Dawson GNovember 2006Not Determined
16816239Create StudyEffects of season of birth on autism spectrum disorders: fact or fiction?The American journal of psychiatryKolevzon A, Weiser M, Gross R, Lubin G, Knobler HY, Schmeidler J, Silverman JM, Reichenberg AJuly 2006Not Determined
16810564Create StudyThe collateral effects of joint attention training on social initiations, positive affect, imitation, and spontaneous speech for young children with autism.Journal of autism and developmental disordersWhalen, Christina; Schreibman, Laura; Ingersoll, BrookeJuly 2006Not Determined
16752361Create StudyStratification based on language-related endophenotypes in autism: attempt to replicate reported linkage.American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric GeneticsSpence, Sarah J; Cantor, Rita M; Chung, Lien; Kim, Sharon; Geschwind, Daniel H; Alarcón, MaricelaSeptember 5, 2006Not Determined
16685181Create StudyEarly intensive behavioral treatment: replication of the UCLA model in a community setting.Journal of developmental and behavioral pediatrics : JDBPCohen H, Amerine-Dickens M, Smith TApril 2006Not Determined
16649827Create StudySelective serotonin reuptake inhibitors in autism: a review of efficacy and tolerability.The Journal of clinical psychiatryKolevzon, Alexander; Mathewson, Karen A; Hollander, EricMarch 2006Not Determined
16616719Create StudyLack of evidence for association of the serotonin transporter gene SLC6A4 with autism.Biological psychiatryRamoz N, Reichert JG, Corwin TE, Smith CJ, Silverman JM, Hollander E, Buxbaum JDJuly 15, 2006Not Determined
16445396Create StudyEvent-related potential (ERP) indices of infants' recognition of familiar and unfamiliar objects in two and three dimensions.Developmental scienceCarver LJ, Meltzoff AN, Dawson GJanuary 2006Not Determined
16395125Create StudyAutism and ultraconserved non-coding sequence on chromosome 7q.Psychiatric geneticsRichler E, Reichert JG, Buxbaum JD, McInnes LAFebruary 2006Not Determined
16262987Create StudyNeurocognitive and electrophysiological evidence of altered face processing in parents of children with autism: implications for a model of abnormal development of social brain circuitry in autism.Development and psychopathologyDawson G, Webb SJ, Wijsman E, Schellenberg G, Estes A, Munson J, Faja S2005Not Determined
16203980Create StudyMultiplexed variation scanning for 1,000 amplicons in hundreds of patients using mismatch repair detection (MRD) on tag arrays.Proceedings of the National Academy of Sciences of the United States of AmericaFaham M, Zheng J, Moorhead M, Fakhrai-Rad H, Namsaraev E, Wong K, Wang Z, Chow SG, Lee L, Suyenaga K, Reichert J, Boudreau A, Eberle J, Bruckner C, Jain M, Karlin-Neumann G, Jones HB, Willis TD, Buxbaum JD, Davis RWOctober 11, 2005Not Determined
16184061Create StudyPropofol sedation for longitudinal pediatric neuroimaging research.Journal of neurosurgical anesthesiologyAmundsen LB, Artru AA, Dager SR, Shaw DW, Friedman S, Sparks B, Dawson GOctober 2005Not Determined
16167091Create StudyIndividuals with autism spectrum disorder show normal responses to a fear potential startle paradigm.Journal of autism and developmental disordersBernier, Raphael; Dawson, Geraldine; Panagiotides, Heracles; Webb, SaraOctober 2005Not Determined
16161095Create StudyAssessment of social communication skills in preschoolers.Mental retardation and developmental disabilities research reviewsLanda RJ2005Not Determined
16119475Create StudyVariation in early developmental course in autism and its relation with behavioral outcome at 3-4 years of age.Journal of autism and developmental disordersWerner, Emily; Dawson, Geraldine; Munson, Jeffrey; Osterling, JulieJune 2005Not Determined
16083327Create StudyAutism spectrum disorders: emerging pharmacotherapy.Expert opinion on emerging drugsBostic JQ, King BHAugust 2005Not Relevant
15939406Create StudyStriatal volume on magnetic resonance imaging and repetitive behaviors in autism.Biological psychiatryHollander E, Anagnostou E, Chaplin W, Esposito K, Haznedar MM, Licalzi E, Wasserman S, Soorya L, Buchsbaum MAugust 1, 2005Not Determined
15850743Create StudyCortical thickness analysis in autism with heat kernel smoothing.NeuroImageChung MK, Robbins SM, Dalton KM, Davidson RJ, Alexander AL, Evans ACMay 1, 2005Not Determined
15843104Create StudyUnderstanding the nature of face processing impairment in autism: insights from behavioral and electrophysiological studies.Developmental neuropsychologyDawson G, Webb SJ, McPartland J2005Not Determined
15796118Create StudyImprovement in cognitive and language skills from preschool to adolescence in autism.Journal of autism and developmental disordersSigman, Marian; McGovern, Corina WFebruary 2005Not Determined
15750588Create StudyGaze fixation and the neural circuitry of face processing in autism.Nature neuroscienceDalton, Kim M; Nacewicz, Brendon M; Johnstone, Tom; Schaefer, Hillary S; Gernsbacher, Morton Ann; Goldsmith, H H; Alexander, Andrew L; Davidson, Richard JApril 2005Not Determined
15749245Create StudyThe teratology of autism.International journal of developmental neuroscience : the official journal of the International Society for Developmental NeuroscienceArndt, Tara L; Stodgell, Christopher J; Rodier, Patricia MApril 2005Not Determined
15647058Create StudyLinks between social and linguistic processing of speech in preschool children with autism: behavioral and electrophysiological measures.Developmental scienceKuhl PK, Coffey-Corina S, Padden D, Dawson GJanuary 2005Not Determined
15575414Create StudyThe genetics of autism.Seminars in pediatric neurologySpence SJSeptember 2004Not Determined
15454078Create StudyCa(V)1.2 calcium channel dysfunction causes a multisystem disorder including arrhythmia and autism.CellSplawski, Igor; Timothy, Katherine W; Sharpe, Leah M; Decher, Niels; Kumar, Pradeep; Bloise, Raffaella; Napolitano, Carlo; Schwartz, Peter J; Joseph, Robert M; Condouris, Karen; Tager-Flusberg, Helen; Priori, Silvia G; Sanguinetti, Michael C; Keating, Mark TOctober 1, 2004Not Determined
15335344Create StudyEvent-related brain potentials reveal anomalies in temporal processing of faces in autism spectrum disorder.Journal of child psychology and psychiatry, and allied disciplinesMcPartland J, Dawson G, Webb SJ, Panagiotides H, Carver LJOctober 2004Not Determined
15325371Create StudyLess white matter concentration in autism: 2D voxel-based morphometry.NeuroImageChung MK, Dalton KM, Alexander AL, Davidson RJSeptember 2004Not Determined
15274045Create StudyFamilial symptom domains in monozygotic siblings with autism.American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric GeneticsKolevzon, Alexander; Smith, Christopher J; Schmeidler, James; Buxbaum, Joseph D; Silverman, Jeremy MAugust 15, 2004Not Determined
15246704Create StudySex-specific development of cortical monoamine levels in mouse.Brain research. Developmental brain researchConnell S, Karikari C, Hohmann CFJuly 19, 2004Not Determined
15056512Create StudyLinkage and association of the mitochondrial aspartate/glutamate carrier SLC25A12 gene with autism.The American journal of psychiatryRamoz, Nicolas; Reichert, Jennifer G; Smith, Christopher J; Silverman, Jeremy M; Bespalova, Irina N; Davis, Kenneth L; Buxbaum, Joseph DApril 2004Not Determined
14999178Create StudyComorbidity in compulsive hoarding: a case report.CNS spectrumsKaplan, Alicia; Hollander, EricJanuary 2004Not Determined
14999175Create StudyImpact of recent findings on study design of future autism clinical trials.CNS spectrumsHollander, Eric; Phillips, Ann; King, Bryan H; Guthrie, Donald; Aman, Michael G; Law, Paul; Owley, Thomas; Robinson, RickiJanuary 2004Not Determined
14979766Create StudyEarly social attention impairments in autism: social orienting, joint attention, and attention to distress.Developmental psychologyDawson G, Toth K, Abbott R, Osterling J, Munson J, Estes A, Liaw JMarch 2004Not Determined
14699429Create StudyLinkage analysis for autism in a subset families with obsessive-compulsive behaviors: evidence for an autism susceptibility gene on chromosome 1 and further support for susceptibility genes on chromosome 6 and 19.Molecular psychiatryBuxbaum JD, Silverman J, Keddache M, Smith CJ, Hollander E, Ramoz N, Reichert JGFebruary 2004Not Determined

Relevant Publications
PubMed IDStudyTitleJournalAuthorsDate
No records found.

You can use "Add New Data Expected" to add exsiting structures and create your project's list. However, this is also the method you can use to request new structures be created for your project. When adding the Data Expected item, if the structure already exists you can locate it and specify your dates and enrollment. To add a new structure and request it be defined in the Data Dictionary, select Upload Definition and attach the definition or material needed to create it, including manual, codebooks, forms, etc. If you have multiple files, please upload a zipped archive containing them all.

Expected dates should be selected based on the standard Data Sharing Regimen and are restricted to within date ranges based on the project start and end dates.

Data Expected
Data ExpectedTargeted EnrollmentInitial SubmissionSubjects SharedStatus
No records found.
Structure not yet defined

Collection Owners and those with Collection Administrator permission, may edit a collection. The following is currently available for Edit on this page:

Associated Studies

Studies that have been defined using data from a Collection are important criteria to determine the value of data shared. The number of subjects column displays the counts from this Collection that are included in a Study, out of the total number of subjects in that study. The Data Use column represents whether or not the study is a primary analysis of the data or a secondary analysis. State indicates whether the study is private or shared with the research community.

Study NameAbstractCollection/Study SubjectsData UsageState
Examining the validity of the use of ratio IQs in psychological assessments IQ tests are amongst the most used psychological assessments, both in research and clinical settings. For participants who cannot complete IQ tests normed for their age, ratio IQ scores (RIQ) are routinely computed and used as a proxy of IQ, especially in large research databases to avoid missing data points. However, because it has never been scientifically validated, this practice is questionable. In the era of big data, it is important to examine the validity of this widely used practice. In this paper, we use the case of autism to examine the differences between standard full-scale IQ (FSIQ) and RIQ. Data was extracted from four databases in which ages, FSIQ scores and subtests raw scores were available for autistic participants between 2 and 17 years old. The IQ tests included were the MSEL (N=12033), DAS-II early years (N=1270), DAS-II school age (N=2848), WISC-IV (N=471) and WISC-V (N=129). RIQs were computed for each participant as well as the discrepancy (DSC) between RIQ and FSIQ. We performed two linear regressions to respectively assess the effect of FSIQ and of age on the DSC for each IQ test, followed by additional analyses comparing age subgroups as well as FSIQ subgroups on DSC. Participants at the extremes of the FSIQ distribution tended to have a greater DSC than participants with average FSIQ. Furthermore, age significantly predicted the DSC, with RIQ superior to FSIQ for younger participants while the opposite was found for older participants. These results question the validity of this widely used alternative scoring method, especially for individuals at the extremes of the normal distribution, with whom RIQs are most often employed.1007/17423Secondary AnalysisPrivate
Controls for SCCRIPTo establish a well characterized cohort for pediatric patients living with sickle cell disease1/11185Secondary AnalysisPrivate
Characterizing Auditory Hyperreactivity in AutismObjective: To answer the following research questions: 1) What is the prevalence of auditory hyper-reactivity in ASD? 2) Does auditory hyper-reactivity severity change with age? and 3) What are the most common auditory stimuli reported to be bothersome? Research Design: Primarily descriptive secondary data analysis. Methods: Type of data: Questionnaire items regarding auditory hyper-reactivity will be filtered from: Autism Diagnostic Interview-Revised, Sensory Profile (all forms), Sensory Over-Responsivity Scale, and Sensory Experiences Questionnaire in addition to demographics (i.e., age, race, ethnicity, diagnoses). Analysis Plan: Descriptive statistics, tables and figures will be used to summarize the prevalence and severity of auditory hyper-reactivity by age. Linear regression modeling will be used to evaluate changes in auditory hyper-reactivity by age. If data is available for control subjects, statistical analyses will be conducted for means comparison (ASD vs. non-ASD). 31/7001Secondary AnalysisPrivate
The effect of compensatory mechanisms during and after pregnancy on a child's developmentEarly childhood involves rapid processes of human growth leading to different trajectories in physical, cognitive, social, and emotional development (Graignic-Philippe et al., 2014). These processes are influenced by a wide variety of factors such as maternal health, environmental stressors, and early childhood experiences. Current literature has shown how exposure to both acute and chronic stress during pregnancy have a pathogenetic effect throughout childhood (Kim & Leventhal, 2015; Rice, et al, 2010), leading to neurotypical or atypical development. Studies have shown how these stressors are linked neurodevelopmental disorders such Autism Spectrum Disorders (Zerbo et al., 2015; Atladóttir et al., 2012) or Attention Deficit Hyperactivity Disorder (Rosenqvist et al., 2019). In recent years, there has been a shift from traditional diagnostic research models to synthesis of different scientific fields to map lifecourse development in order for rapid translation into healthcare practices (Halfon et al., 2014). Whilst there are studies showing links between stress and atypical developmental outcomes, there is still very limited literature on compensatory mechanisms found pre- and post-pregnancy, which illustrate development of protective factors (such as presence of self-regulation, high verbal intelligence, sociability, adept social communication) against atypical developmental outcomes. This study aims to identify and measure the presence of these protective factors that appear to guard against or mitigate the emergence of neurodevelopmental disorders. Therefore, nationwide and longitudinal data are needed in order to accurately create risk models in order to map developmental trajectories. 255/5717Secondary AnalysisPrivate
Autism Sensory Research Consortium Cross-lab Integrative Data Analysis Since 2013, when sensory features were officially added to the diagnostic criteria for autism, research into the sensory manifestations of the condition has increased dramatically. However, the majority of this research has primarily been conducted using small laboratory-based samples of children on the autism spectrum, substantially limiting the hypotheses that can be tested in any one dataset and the generalizability of results to the wider autistic population. The Autism Sensory Research Consortium (ASRC), funded by the Nancy Lurie Marks Family Foundation, represents the first major international collaboration of over a dozen research groups that study sensory functioning in autism. As a major thrust of this collaboration, the ASRC has begun a data sharing initiative, in which all participating labs can contribute existing data from their past and present research studies to a centralized database. These “Big Data” can then be systematically examined using powerful large-sample statistical techniques such as structural equation modeling and item response theory, which will allow researchers to test more complex hypotheses regarding the nature of sensory differences in autism and their relationships with sociodemographic and non-sensory clinical features. Once data from all sites has been pooled, it will be analyzed using a method called integrative data analysis, which is specially designed to derive insights from large and heterogeneous samples. One major advantage of this methodology is the ability to construct and test measurement models of sensory symptoms, determining the most appropriate set of questions for assessing each construct and making sure that the scales do not produce biased comparisons when they are examined across diagnostic groups or subsets of the autistic population. Furthermore, measurement models can be constructed to bridge multiple questionnaires, allowing for the calculation of robust composite scores that can be compared between studies that only administered items from one of the contributing questionnaires. These models can further facilitate pooling of data across studies, allowing us to amass even larger datasets to answer questions about sensory function in the autistic population. Furthermore, moving forward, the composite sensory measures from the integrative data analysis can be employed in other studies, providing investigators in sensory autism research with a suite of reliable and valid behavioral measures that can be used as outcomes in trials of interventions targeting these symptoms. In the long term, this project has the potential to help us better understand the nature of sensory function in persons on the spectrum, as well as how sensory alterations relate to broader features of the condition—specifically, for whom and/or at what point in development sensory features are most predictive of core autism behaviors or other meaningful clinical outcomes such as language acquisition and adaptive behavior. Incorporation of neuroscientific data collected within the ASRC can also possibly shed some light on the neural basis of sensory disruptions in the autistic population. All of this will help to lay a foundation for future work testing the efficacy of candidate interventions aimed at improving sensory function and more distal skills in autistic individuals.239/2110Secondary AnalysisPrivate
Psychometric Analysis of the Social Communication Questionnaire Using an Item-Response Theory Framework: Implications for the Use of the Lifetime and Current FormsThe Social Communication Questionnaire (SCQ) was developed as a screener of Autism Spectrum Disorder (ASD). To date, the majority of the SCQ utility studies focused on its external validity (e.g., ROC curve analyses), but very few have addressed the internal validity issues. With samples consisting of 2,134 individuals available from the National Database for Autism Research (NDAR), the current study examined the factor structure, item-level characteristics, and measurement equivalence of the SCQ forms (i.e., Lifetime form and Current form) using both the classical true score theory and the item response theory (IRT). While our findings indicate sufficient psychometric properties of the SCQ Lifetime form, measurement issues emerged with respect to the SCQ Current form. These issues include lower internal consistencies, a weaker factor structure, lower item discriminations, significant pseudo-guessing effects, and subscale-level measurement bias. Thus, we caution researchers and clinicians about the use of the SCQ Current form. In particular, it seems inappropriate to use the Current form as an alternative to the Lifetime form among children younger than 5 years old or under other special situations (e.g., teacher-report data), although such practices were advised by the publisher of the SCQ. Instead, we recommend modifying the wording of the Lifetime form items rather than switching to the Current form where a 3-month timeframe is specified for responding to SCQ items. Future studies may consider investigating the association between the temporality of certain behaviors and the individual’s potential for being diagnosed with ASD, as well as the age neutrality of the SCQ.6/2054Secondary AnalysisShared
Unravelling the Collective Diagnostic Power Behind the Features in the Autism Diagnostic Observation ScheduleBackground: Autism is a group of heterogeneous disorders defined by deficits in social interaction and communication. Typically, diagnosis depends on the results of a behavioural examination called the Autism Diagnostic Observation Schedule (ADOS). Unfortunately, administration of the ADOS exam is time-consuming and requires a significant amount of expert intervention, leading to delays in diagnosis and access to early intervention programs. The diagnostic power of each feature in the ADOS exam is currently unknown. Our hypothesis is that certain features could be removed from the exam without a significant reduction in diagnostic accuracy, sensitivity or specificity. Objective: Determine the smallest subset of predictive features in ADOS module-1 (an exam variant for patients with minimal verbal skills). Methodology: ADOS module-1 datasets were acquired from the Autism Genetic Resource Exchange and the National Database for Autism Research. The datasets contained 2572 samples with the following labels: autism (1763), autism spectrum (513), and non-autism (296). The datasets were used as input to 4 different cost-sensitive classifiers in Weka (functional trees, LADTree, logistic model trees, and PART). For each classifier, a 10-fold cross validation was preformed and the number of predictive features, accuracy, sensitivity, and specificity was recorded. Results & Conclusion: Each classifier resulted in a reduction of the number of ADOS features required for autism diagnosis. The LADtree classifier was able to obtain the largest reduction, utilizing only 10 of 29 ADOS module-1 features (96.8% accuracy, 96.9% sensitivity, and 95.9% specificity). Overall, these results are a step towards a more efficient behavioural exam for autism diagnosis. 35/1832Secondary AnalysisShared
Computer-Based Testing to Shorten the Social Communication Questionnaire (SCQ): A Proof-of-Principle Study of the Lifetime and Current FormsThe Social Communication Questionnaire (SCQ) is a 40-item instrument designed to screen children at risk for Autism Spectrum Disorder (ASD). Both Lifetime and Current forms of the scale are available. Although these forms are manageable for many respondents, their use may result in substantial respondent and administrative burden, particularly among individuals who have difficulty reading, have physical illness, and/or are asked to take multiple questionnaires. The objective of this research was to examine the potential of two stopping rules for computer-based testing (namely, curtailment and stochastic curtailment) to shorten the SCQ without compromising its screening properties. A retrospective analysis was conducted using data from the National Database for Autism Research (NDAR); responses regarding 1236 at-risk individuals from the SCQ Lifetime and 709 at-risk individuals from the SCQ Current were analyzed. In post-hoc simulation, curtailment reduced mean test lengths by 29% to 44% compared to the full-length Lifetime form, and by 25% to 39% compared to the full-length Current form, while providing the same screening result as the corresponding full-length form in 100% of cases. Stochastic curtailment made further reductions in test length, but was not always concordant with the full-length form’s screening result. These findings suggest that curtailment has potential to improve the efficiency of the SCQ in computer-based administrations and should be tested prospectively.6/1820Secondary AnalysisPrivate
Automated Autism Diagnosis using Phenotypic and Genotypic Attributes: Phase IThe ultimate goal of this project is to develop a predictive system that can automate the diagnosis process for autism using phenotypic and genotypic attributes for classification. At this time, only a first phase is being pursued: starting with scores from Autism Diagnostic Observation Schedule (ADOS) reports, use data-mining techniques to select the smallest set of the most informative evaluation points that can lead to similar behavioral diagnoses as using all report features. The effort began in March, 2016 after data access to NDAR was granted. This report describes the results from that date through the end of December 2016.33/1045Secondary AnalysisPrivate
Gender as a Moderator of the Association between Social Responsiveness and Cognitive Ability for Children with Autism14/977Secondary AnalysisPrivate
Revising the Social Communication Questionnaire scoring procedures for Autism Spectrum Disorder and potential Social Communication DisorderIn analyzing data from the National Database for Autism Research, we examine revising the Social Communication Questionnaire (SCQ), a commonly used screening instrument for Autism Spectrum Disorder. A combination of Item Response Theory and Mokken scaling techniques were utilized to achieve this and abbreviated scoring of the SCQ is suggested. The psychometric sensitivity of this abbreviated SCQ was examined via bootstrapped Receiver Operator Characteristic (ROC) curve analyses. Additionally, we examined the sensitivity of the abbreviated and total scaled SCQ as it relates to a potential diagnosis of Social (Pragmatic) Communication Disorder (SCD). As SCD is a new disorder introduced with the fifth edition of the Diagnostic and Statistical Manual (DSM-5), we identified individuals with potential diagnosis of SCD among individuals with ASD via mixture modeling techniques using the same NDAR data. These analyses revealed two classes or clusters of individuals when considering the two core areas of impairment among individuals with ASD: social communication and restricted, repetitive patterns of behavior. 7/889Secondary AnalysisShared
Gender differences in restricted and repetitive behaviors and interests in autismBackground: The female autism phenotype has been defined by differences in core autism spectrum disorder (ASD) symptomology related to reciprocal social communication and restricted and repetitive behaviors and interests (RRBI). Previous research on RRBI in ASD has found that affected boys have increased stereotyped and restricted behaviors compared to girls with ASD (Hiller, Young, & Weber, 2014; Mandy et al., 2012). Other domains of RRBI (i.e., self-injurious, compulsive, and insistence on sameness behaviors), which contribute to DSM-5 diagnosis, are less studied and have not been examined across gender. To date, no studies have examined gender differences using a comprehensive RRBI measure, which spans stereotyped, self-injurious, compulsive, insistence on sameness, and restricted behavior domains. Objectives: To investigate whether symptoms of RRBI (i.e., stereotyped, self-injurious, ritualistic, compulsive, insistence on sameness, and restricted behavior), as measured by item-level data on the Repetitive Behavior Scale-Revised (RBS-R), can classify males versus females with ASD. Methods: Participants included 615 youth with ASD (507 males; 82.4%), between 3 and 18 years of age (M=10.26, SD=4.20), who agreed to share data with the National Database for Autism Research (NDAR). A stepwise discriminant function analysis (DFA) was used to predict the degree RBS-R data could correctly classify gender in a large sample of individuals with ASD. Standardized canonical function coefficients (SCFC) from the DFA represent the contribution of each variable to the discrimination between groups, with greater SCFC indicating greater discrimination. Results: DFA results suggest that RBS-R items significantly differentiate girls versus boys with ASD, Wilks’ λ=0.89, χ2=70.79, p<0.001. Of note, gender was classified based on a set of 8 items (see table 1). Interestingly, the items that differentiated boys from girls did not solely consist of higher stereotyped and restricted behavior in boys (as indicated by negative SCFC scores). Half of the items that differentiated gender were higher in females with ASD (as indicated by positive SCFC scores) and from the self-injurious, compulsive, and insistence on sameness domains. This set of RBS-R items had greater success in correctly classifying boys with ASD (67.90%) than in correctly classifying affected girls (61.00%). Conclusions: This study extends findings of gender differences in RRBI for ASD, demonstrating that girls with ASD may demonstrate higher self-injurious, compulsive, and insistence on sameness behavior than affected boys. It is important for future research to disentangle whether these elevated rates of RRBI in girls with ASD are central to the female autism phenotype or an epiphenomenon of the high rates of co-occurring disorders (e.g., anxiety) noted in affected girls. 1/612Secondary AnalysisPrivate
Predictors of self-injurious behaviour exhibited by individuals with autism spectrum disorderPresence of an autism spectrum disorder is a risk factor for development of self-injurious behaviour (SIB) exhibited by individuals with developmental disorders. The most salient SIB risk factors historically studied within developmental disorders are level of intellectual disability, communication deficits and presence of specific genetic disorders. Recent SIB research has expanded the search for risk factors to include less commonly studied variables for people with developmental disorders: negative affect, hyperactivity and impulsivity.220/589Secondary AnalysisShared
Face-processing performance is an independent predictor of social affect as measured by the Autism Diagnostic Observation Schedule across large-scale datasetsFace-processing deficits, while not required for the diagnosis of Autism Spectrum Disorder (ASD), have been associated with impaired social skills—a core feature of ASD; however, the strength and prevalence of this relationship remains unclear. Across 445 participants from the NIMH Data Archive, we examined the relationship between Benton Face Recognition Test (BFRT) performance and Autism Diagnostic Observation Schedule-Social Affect (ADOS-SA) scores. Lower BFRT scores (worse face-processing performance) were associated with higher ADOS-SA scores (higher ASD severity)–a relationship that held after controlling for other factors associated with face processing, i.e., age, sex, and IQ. These findings underscore the utility of face discrimination, not just recognition of facial emotion, as a key covariate for the severity of symptoms that characterize ASD.2/445Secondary AnalysisShared
The Sensitivity and Specificity of the Social Communication Questionnaire for Autism Spectrum Disorder with Respect to AgeScientific Abstract The Social Communication Questionnaire (SCQ) assesses communication skills and social functioning in screening for symptoms of autism-spectrum disorder (ASD). The SCQ is recommended for individuals between 4 to 40 years with a cutoff score of 15 for referral. Mixed findings have been reported regarding the recommended cutoff score’s ability to accurately classify an individual as at-risk for ASD (sensitivity) versus an individual as not at-risk for ASD (specificity). Based on a sample from the National Database for Autism Research (n=344; age: 1.58 to 25.92 years old), the present study examined the SCQ’s sensitivity versus specificity across a range of ages. We recommend that the cutoff scores for the SCQ be re-evaluated with age as a consideration. Lay Abstract The age neutrality of the Social Communication Questionnaire (SCQ) was examined as a common screener for ASD. Mixed findings have been reported regarding the recommended cutoff score’s ability to accurately classify an individual as at-risk for ASD (sensitivity) versus accurately classifying an individual as not at-risk for ASD (specificity). With a sample from the National Database for Autism Research, the present study examined the SCQ’s sensitivity versus specificity. Analyses indicated that the actual sensitivity and specificity scores were lower than initially reported by the creators of the SCQ.3/339Secondary AnalysisShared
Identifying Sex-Specific Cognitive and Diagnostic Profiles for Children on the Autism Spectrum9/252Secondary AnalysisPrivate
Neural Correlates of Restricted Repetitive Behavior in Autism Spectrum DisorderThe objective of this study is to investigate relationships between restricted, repetitive behavior and neural circuitry alterations in autism spectrum disorder (ASD). The neural circuitry mediating restricted, repetitive behaviors is largely unknown, and consequently effective treatments are lacking. In order to perform these investigations we will use the National Database for Autism Research (NDAR) to access questionnaires and assessments related to repetitive behavior as well as MRI, fMRI, and DTI scans from subjects with autism spectrum disorder (ASD) and typically developing controls. We will perform between-group morphological comparisons, as well as assessments of brain connectivity (e.g. diffusion tractography). For subjects with ASD, we will also correlate neuroimaging data to repetitive behavior scores. This study will help to better understand the link between restricted, repetitive behavior and specific brain alterations 1/192Secondary AnalysisPrivate
Critical test items to differentiate individuals with SPCD from those with ASD and typical controlsSocial (pragmatic) communication disorder (SPCD) is a new category in the DSM-5. This study used IRT modelling to analyze archive data of item responses to the Social Communication Question-Lifetime (SCQ) from the National Database of Autism Research (NDAR), to select critical test items that could efficiently differentiate SPCD from ASD and TD. Methods: The SCQ records were downloaded from the NDAR. The item difficulty values and participants ability in the social communication and repetitive behavior and restricted interests were estimated through Winsteps. The items with difficulty values mostly matching the participants ability at the cut-off zones among three groups were selected. Result: The eight test items were identified for screening SPCD with 75% sensitivity. The specificity for differentiating SPCD from TD and ASD is 86.27% and 68.9% respectively. Conclusion: This study provides a short list of critical items that could be used to screen SPCD from TD and ASD. 1/151Secondary AnalysisPrivate
* Data not on individual level
Edit