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View Cohort
        helpcenter.ndastudy.view-cohort

        NDA Help Center

        NDA Study - View Cohort

        The View Cohort shows the Study cohort characteristics which will includes the name, type, sex and age in months range criteria. Note that age and sex restrict the data that can be added to the cohort. Medical criteria and phenotype are also included. Of particular importance on this page are any comments related to included subjects, which may be different than published results, often attributed to data sharing consent.

        Frequently Asked Questions

        • How do I know the characteristics of the cohort?
          The appropriate Medical Criteria, Phenotype, and Sub Type defined by the Study Owner are highlighted. The option trees are automatically expanded so the highlighted options are immediately viewable.

        Glossary

        • Age Range
          Age is expressed in months from 0 (birth) to 1200 (100 years old).
        • Medical Criteria
          NDA defines Medical Criteria as a diagnostically based determination of an individual's disease or condition.
        • Phenotype
          NDA defines Phenotype as any physical, morphologic, or biochemical characteristics that are observable in an individual.
        • Sub Types
          NDA defines Sub Type as a subordinate condition or disease that further characterizes an individual.
        • Cohort Name
          A user defined name for the cohort with a 200 character limit.
        • Cohort Type
          Cohort Type options include Baseline, Control, and Test.
        • Cohort Comments
          Comments further characterize the cohort beyond the options provided in the interface to define the cohort.
        • Cohort Subjects
          The Cohort Subjects provides the number of unique subjects for whom data have been associated with the cohort.
        • Cohort
          Summarizes the characteristics of a group of research subjects. The subject count is noted in parentheses.
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        Study DOI
        Study DOI Status Info
        • DOI: 10.15154/1522624
        • DataCite Status: Findable
        • NDAR Status: Registered
        • DOI Registered with DataCite
        • Public URL Resolves at DOI
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        Laurent Mottron laurent.mottron@gmail.com Analysis Shared
        Click for more info Courchesne, Valérie; Ostrolenk, Alexia
        IQ tests are amongst the most used psychological assessments, both in research and clinical settings. For participants who cannot complete IQ tests normed for their age, ratio IQ scores (RIQ) are routinely computed and used as a proxy of IQ, especially in large research databases to avoid missing data points. However, because it has never been scientifically validated, this practice is questionable. In the era of big data, it is important to examine the validity of this widely used practice. In this paper, we use the case of autism to examine the differences between standard full-scale IQ (FSIQ) and RIQ. Data was extracted from four databases in which ages, FSIQ scores and subtests raw scores were available for autistic participants between 2 and 17 years old. The IQ tests included were the MSEL (N=12033), DAS-II early years (N=1270), DAS-II school age (N=2848), WISC-IV (N=471) and WISC-V (N=129). RIQs were computed for each participant as well as the discrepancy (DSC) between RIQ and FSIQ. We performed two linear regressions to respectively assess the effect of FSIQ and of age on the DSC for each IQ test, followed by additional analyses comparing age subgroups as well as FSIQ subgroups on DSC. Participants at the extremes of the FSIQ distribution tended to have a greater DSC than participants with average FSIQ. Furthermore, age significantly predicted the DSC, with RIQ superior to FSIQ for younger participants while the opposite was found for older participants. These results question the validity of this widely used alternative scoring method, especially for individuals at the extremes of the normal distribution, with whom RIQs are most often employed.
        10.15154/1522624
        Click for more info Secondary Analysis
        Click for more info
        IDCollectionPermission GroupSubjects
        1853 Collaborative Programs of Excellence in Autism (CPEA) NIMH Data Archive1,682
        1854 Studies to Advance Autism Research and Treatment (STAART). NIMH Data Archive1,007
        2027 A Longitudinal MRI Study of Infants at Risk for Autism (ACE 2) NIMH Data Archive565
        1151 Pediatric MRI NIMH Data Archive554
        19 Longitudinal MRI Study of Infants at Risk for Autism NIMH Data Archive519
        2021 Multimodal Developmental Neurogenetics of Females with ASD NIMH Data Archive508
        2115 Detection of ASD at the 1st birthday as standard of care: The Get SET Early Model NIMH Data Archive501
        2066 The CHARGE Study: Childhood Autism Risks From Genetics and the Environment NIMH Data Archive476
        2046 Development of a new autism screening tool for traditionally underserved families NIMH Data Archive474
        2551 Treatment of Attention Deficit Hyperactivity Disorder in Preschool-Age Children (PATS) NIMH Data Archive451
        2290 Early Identification of ASD: Translating Eye Tracking into Practice (Years 6-10) NIMH Data Archive444
        2288 The Autism Biomarkers Consortium for Clinical Trials NIMH Data Archive438
        2384 Early Brain Development in Twins NIMH Data Archive426
        1866 1/2 Development of a Screening Interview for Research Studies of ASD NIMH Data Archive403
        2080 Smart Early Screening for Autism and Communication Disorders in Primary Care NIMH Data Archive383
        2003 Autism: Social and Communication Predictors in Siblings (Landa) AND Effects of Active Motor and Social Training on Developmental Trajectories in Infants at High-risk for Autism Spectrum Disorders (Libertus) NIMH Data Archive350
        2557 Environmental Influence on Infant Microbiome Development and ASD Symptoms NIMH Data Archive317
        1654 UW ACE Extended Family Study NIMH Data Archive300
        1 UIC ACE: Translational Studies of Insistence on Sameness in Autism NIMH Data Archive260
        1946 Autism Risk, Prenatal Environmental Exposures, and Pathophysiologic Markers NIMH Data Archive259
        2113 Addressing systemic health disparities in early ASD identification and treatment NIMH Data Archive255
        1600 Early Autism Risk Longitudinal Investigation (EARLI) Network NIMH Data Archive245
        2355 Neurobehavioral Research on Infants at Risk for Language Delay and ASD NIMH Data Archive233
        2028 Mechanisms of Risk and Resilience in ASD: Ontogeny, Phylogeny and Gene Disruption NIMH Data Archive231
        1886 PDN Screening Data NIMH Data Archive228
        2293 Components of Emotional Processing in Toddlers with ASD NIMH Data Archive227
        2004 1/3, 2/3, and 3/3: Sequencing Autism Spectrum Disorder Extended Pedigrees NIMH Data Archive217
        2101 Phenotypic Characterization of Gene Disrupting Mutations in ASD NIMH Data Archive212
        2368 Clinical and Immunological Investigations of Subtypes of Autism NIMH Data Archive202
        8 Yale Autism Center of Excellence: Mechanisms of Social Engagement in the Autism Spectrum Disorders NIMH Data Archive196
        2026 Biomarkers of Developmental Trajectories and Treatment in ASD NIMH Data Archive193
        2976 Autism Genetics Phase II: Increasing representation of human diversity NIMH Data Archive192
        2121 Mobilizing Community Systems to Engage Families in Early ASD Detection & Services NIMH Data Archive177
        2036 Intervention effects of intensity and delivery style for toddlers with ASD NIMH Data Archive174
        1923 Components of Limited Activity Monitoring in Toddlers with ASD NIMH Data Archive173
        2179 Neural markers of shared gaze during simulated social interactions in ASD \-Modal Automated Assessment of Behavior during Social Interactions in Children with ASD NIMH Data Archive171
        10 UCLA Sigman/Bookheimer ACE and ARRA NIMH Data Archive166
        2329 Cincinnati MR Imaging of Neurodevelopment (C-MIND) NIMH Data Archive162
        2008 Early Biomarkers of Autism Spectrum Disorders in infants with Tuberous Sclerosis NIMH Data Archive158
        14 Early Pharmacotherapy Guided by Biomarkers in Autism NIMH Data Archive157
        2076 1/3 to 3/3 Treatment of anxiety in autism spectrum disorder NIMH Data Archive150
        2253 Neurophenotypic Trajectories and Behavioral Outcomes in Autism Spectrum Disorder NIMH Data Archive143
        6 Biological and Information Processing Mechanisms Underlying Autism NIMH Data Archive141
        1358 Biological Signatures of Autism NIMH Data Archive140
        2007 Treatment of Autism Symptoms in Children (TASC): Initial RCT with Active Control NIMH Data Archive137
        2349 RUPP PI PDD: Drug and Behavioral Therapy for Children With Pervasive Developmental Disorders NIMH Data Archive121
        2549 Treatment of Adolescent Suicide Attempters (TASA) NIMH Data Archive117
        2845 Attentional, temperamental, and physiological process underlying anxiety in preschoolers with ASD NIMH Data Archive113
        2555 A longitudinal study of brain development in children with autism NIMH Data Archive112
        2761 Charting the trajectory of executive control in autism in order to optimize delivery of intervention NIMH Data Archive111
        2093 Sporadic Mutations and Autism Spectrum Disorders NIMH Data Archive106
        2778 Heterogeneity in Autism Spectrum Disorders: Biological Mechanisms, Trajectories, and Treatment Response NIMH Data Archive104
        1985 Evaluating the Time-Dependent Unfolding of Social Interactions in Children with Autism NIMH Data Archive103
        2149 Methylphenidate for Hyperactivity and Impulsiveness in Children and Adolescents With Pervasive Developmental Disorders (RUPP MPH PDD) NIMH Data Archive103
        2108 Neural Phenotypes of Females with Autism Spectrum Disorder NIMH Data Archive100
        2335 The role of parent phenotype in parent-mediated language interventions for autism NIMH Data Archive98
        16 Intensive Intervention for Toddlers With Autism (EARLY STEPS) NIMH Data Archive98
        1856 Early Language Development within the Autism Spectrum NIMH Data Archive95
        2386 Efficacy of the Direct Instruction Language for Learning Program to Promote Expressive and Receptive Language in Children with Autism Spectrum Disorder NIMH Data Archive95
        2013 Magnetoencephalographic studies of lexical processing and abstraction in autism NIMH Data Archive90
        2321 Efficacy of Parent-implemented Treatment in Infant Siblings of Children With ASD NIMH Data Archive87
        1906 Atypical Late Neurodevelopment in Autism NIMH Data Archive86
        2070 Eyeblink conditioning in school-aged children with ASD NIMH Data Archive85
        2622 Using SMART Treatment Design to Evaluate Applied Behavior Analysis Interventions on Communication in Preschool Children with Autism NIMH Data Archive82
        2129 Biological Determinants of Brain Variation in Autism NIMH Data Archive81
        2556 Behavioral Economic Measures of Sensitivity to Social Reward in Children with ASD NIMH Data Archive79
        2664 How Autism Affects Speech in Multitalker Environments NIMH Data Archive79
        2077 Gaze Modification Strategies for Toddlers with ASD NIMH Data Archive78
        2821 Cellular, molecular, and functional imaging approaches to understanding early neurodevelopment in autism NIMH Data Archive72
        2599 A Multimedia Screening System for Early ASD Identification in Diverse Populations NIMH Data Archive69
        2338 Multimodal Imaging of Early Neural Signature in Autism Spectrum Disorder NIMH Data Archive62
        2878 Social Rhythmic Entrainment and Language Development in Autism Spectrum Disorders NIMH Data Archive60
        1965 Longitudinal Studies of Autism Spectrum Disorders: From 2 to 23 NIMH Data Archive60
        1904 Functional Neuroimaging of Attention in Autism NIMH Data Archive56
        2942 Complex versus Essential Autism: A Developmental Study of Risk NIMH Data Archive56
        2559 Neural Mechanisms of CBT for Anxiety in Children with Autism Spectrum Disorder NIMH Data Archive56
        2072 Intrinsic Brain Architecture of Young Children with Autism While Awake and Asleep NIMH Data Archive55
        2771 Emergent Gaze Perception in Autism Spectrum Disorder NIMH Data Archive54
        2441 Structural and Functional Characteristics of XYY - Relationship to ASD NIMH Data Archive53
        1862 Electrophysiologic Studies of Language Impairment in ASD (Years 1-5) NIMH Data Archive52
        2281 Predictors of Cognitive Development in Autism Spectrum Disorder NIMH Data Archive51
        2025 Minimally Verbal ASD: From Basic Mechanisms to Innovative Interventions NIMH Data Archive47
        2151 Placebo-Controlled Study of Risperidone for the Treatment of Children and Adolescents With Autism and Negative Behavioral Symptoms NIMH Data Archive46
        1885 Predicting Useful Speech in Children With Autism NIMH Data Archive45
        2049 Efficacy of Relationship Development Intervention and Parent-Implemented Applied Behavior NIMH Data Archive45
        3122 Can novel telemedicine tools reduce disparities related to early identification of autism NIMH Data Archive44
        3055 Mapping Dimensional Aspects of Biobehavioral Threat Reactivity in Young, Violence-Exposed Children: Linkages to Fear and Distress NIMH Data Archive44
        2591 Quantification of Predictive Motor Impairments in Individuals with ASD NIMH Data Archive42
        2777 Center for the Development of Phenotype-Based Treatments of Autism Spectrum Disorder NIMH Data Archive41
        3022 Electrophysiological Markers for Interventions in Phelan-McDermid Syndrome and Idiopathic Autism NIMH Data Archive38
        2702 The Autism MEAL Plan: A Parent Training Curriculum to Manage Eating Aversions and Limited Variety among Children with Autism NIMH Data Archive38
        2706 Thalamic activity and structure and surface neural oscillations in autism NIMH Data Archive37
        1501 Neural and Behavioral Outcomes of Social Skills Groups in Children with ASD NIMH Data Archive35
        1920 Visual attention and fine motor coordination in infants at risk for autism NIMH Data Archive35
        2183 Identifying Biomarkers for Early Detection of Prosody Disorders in ASD using Electroglottography NIMH Data Archive35
        2251 Developmental Synaptopathies Associated with TSC, PTEN and SHANK3 Mutations NIMH Data Archive34
        1300 Behavioral Treatment for Autism in Community Settings Using a Telehealth Network NIMH Data Archive33
        2029 Autism genetics: homozygosity mapping and functional validation (Years 1-5) NIMH Data Archive32
        2510 Kansas Intellectual and Developmental Disabilities Research Center NIMH Data Archive32
        2799 A Novel Framework for Impaired Imitation in ASD NIMH Data Archive32
        2495 Functions and Development of the Mirror Neuron System NIMH Data Archive32
        2710 Functional connectivity substrates of social and non-social deficits in ASD NIMH Data Archive29
        2774 Improving Child-Treatment Fit in Autism Early Intervention NIMH Data Archive28
        2038 Gender and Cognitive Profile as Predictors of Functional Outcomes in School-Aged Children NIMH Data Archive22
        2035 Autism Genetics, Phase II: Increasing Representation of Human Diversity NIMH Data Archive20
        2012 Optimization of Fidelity Procedures for Pivotal Response Training in Autism NIMH Data Archive19
        1958 A Family-Genetic Study of Autism and Fragile X Syndrome NIMH Data Archive19
        2566 Direct Examination of Imitation-Based Learning in Autism NIMH Data Archive17
        2740 Developmental Changes in Neural Processes Underlying Inattention, Impulsivity and Regulation NIMH Data Archive16
        2181 Sex Differences in the Neural Mechanisms of Treatment Response NIMH Data Archive12
        2005 Pivotal Response Treatment for Infants at Risk for ASD: A Pilot Intervention NIMH Data Archive10
        1888 Emergence and Stability of Autism in Fragile X Syndrome NIMH Data Archive9
        2262 Comparing Behavioral Assessments Using Telehealth for Children with Autism NIMH Data Archive8
        20 CBT for Anxiety in Adolescents with Autism NIMH Data Archive8
        2192 Piloting Treatment with Insulin-Like Growth Factor-1 in Phelan-McDermid Syndrome NIMH Data Archive7
        2503 A new treatment for minimally verbal girls with ASD NIMH Data Archive5
        2424 Neurobiology of Autism With Macrocephaly NIMH Data Archive5
        3081 Neurophysiological and neuroanatomical processes related to Autism Spectrum Disorder in Neurofibromatosis Type 1 NIMH Data Archive5
        9 Biomarkers of Autism at 12 Months: From Brain Overgrowth to Genes NIMH Data Archive5
        1201 Induced pluripotent cells in ASD with macrocephaly NIMH Data Archive5
        1800 Initial Investigation of Prevention of ASD in Infants at Risk NIMH Data Archive4
        2169 Human Clinical Trial of IGF-1 in Children with Idiopathic ASD NIMH Data Archive3
        2266 Inhibitory dysfunction in autism NIMH Data Archive2
        2250 A feasibility study for prevention and safety training for children with autism NIMH Data Archive1
        3101 Alpha oscillations and working memory deficits in ADHD: A multimodal imaging investigation NIMH Data Archive1
        2322 Electrophysiologic Studies of Language Impairment in ASD (Years 6-10) NIMH Data Archive1
        Analysis
        Age: 0 to 1,260 months
        Sex: Both
        helpcenter.ndastudy.summary-tab

        NDA Help Center

        NDA Study - Summary Tab

        An NDA Study describes an analysis, pipeline result, or curated data release - including the cohorts, measures, and methods - referencing the underlying source data in the NDA. Once the data is referenced and the study is shared, the underlying data will not change. It will be immutable allowing others to access those data without change into near perpetuity. Only the assessments (i.e. typically rows in a database) and outcome measures (i.e. columns in a database) included in the study are shared. By sharing data this way (e.g. specific outcome measures by subject/timepoint) an ongoing project's other unpublished data - typically other research aims - will remain embargoed according to a project's established data sharing schedule (see collection).

        When a study is created, a Digital Object Identifier (DOI) is reserved by the NDA, but will not be active. Once the study is shared, the DOI will then be issued and if associated with a publication, the NDA DOI will be linked to the publication's DOI.

        Frequently Asked Questions

        • How can I get access to an NDA Study if I am involved in creating/modifying the NDA Study?
          The individual listed as an Investigator on the General tab of the NDA Collection and any individuals defined as administrators can be provided this privilege. When the study is shared, all of those that have approved access to the data are given read-only access.

        Glossary

        • Abstract
          The Abstract of the publication or other public disclosure of analysis results. The publication abstract is automatically imported when creating a new NDA Study from a Create Study link associated with a Publication listed in a Collection. The field is editable.
        • Documents
          Provides links to additional documentation to help explain the NDA Study.
        • Cohort
          Summarizes the characteristics of a group of research subjects. The subject count is noted in parentheses.
        • Data Analysis
          Summarizes the Data Analysis methods used.
        • Data Usage
          Identifies the NDA Study as a Primary Analysis or Secondary Analysis.
        • Digital Object Identifier (DOI)
          A persistent and unique identifier that is issued for each NDA Study that may increase the visibility of a researcher's work. Authors are expected to reference the location of data in the publication using the DOI.
        • Download Button
          Adds all data from the current Collection or NDA Study to the Filter Cart.
        • Investigators
          The authors of the publication or other public disclosure of analysis results. The publication's authors are automatically imported when creating a new NDA Study from a Create Study link associated with a Publication listed in a Collection. The field is editable and uses a last name, first name format with multiple names separated by semicolons.
        • Primary Analysis
          Primary Analysis is one of the Data Use types NDA recognizes for NDA Studies. It indicates that the NDA Study's creator was involved in the collection of the data (in whole or in part) used in the NDA Study. In other words, at least some and potentially all of the data used was originally collected by the creator of the NDA Study. A Primary Analysis Study.
        • NDA Study Owner
          The NDA user, who does not necessarily have to be one of the Investigators listed in the NDA Study, primarily involved in creating the NDA Study who is serving as the point of contact. The NDA user who creates the NDA Study is automatically assigned as the Study Owner.
        • Private
          The term 'Private' generally means not available to others; however, there are some slightly different meanings based on what is Private. The default state for an NDA Collection, NDA Study, Supporting Documentation, and data is Private and, therefore, accessible only to those users with appropriate Privileges so it will not be viewable and searchable publicly. A Collection may be Shared while the data and Supporting Documentation remain Private.
        • Results
          Provides a link to the publication or other public disclosure of analysis results defined in the NDA Study.
        • Secondary Analysis
          Secondary Analysis is one of the Data Use types NDA recognizes for NDA Studies. It indicates that the NDA Study's creator was not involved in the collection of the data (in whole or in part) used in the NDA Study, but was involved in the analysis of those data. In other words, none of the data used was originally collected by the creator of the NDA Study. A Secondary Analysis Study will provide an Attribution Report listing the Collections and the researchers responsible for collecting and depositing the original data.
        • Study Type
          The NDA Study Type can be either Analysis (i.e. often associated with a computational pipeline), Clinical Trial, Finding (i.e. a result associated with a publication, or Release (i.e. a dataset release, often annually) to indicate the type of work defined in the NDA Study. Studies, once shared do not change.
        • Analysis Study Type
          The Analysis Study Type is primarily used to share a pipeline; however, it could be used to share a statistical analysis or method.
        • Release Study Type
          A static, curated data set.
        • Finding Study Type
          The Finding Study Type associates data to a publication or some type of result.
        • Clinical Trial Study Type
          A Clinical Trial Study is a finding specific to a clinical trial.
        • Study ID Number
          The Study ID number is a unique three digit number routinely expressed as S### that is assigned by the NDA.
        • Study State
          The Study State indicates whether the Study is viewable, searchable, and if the associated data can be accessed by users with appropriate data access Permissions. The default Study State is Private, which means that only the Collection Owner and users with Read Only Privileges. Only the Study Owner can Share the Study.
        • Study Title
          The Study Title is generally the title of the publication or other public disclosure of analysis results. The publication title is automatically imported when creating a new NDA Study from a Create Study link associated with a Publication listed in a Collection. The field is editable.
        • Edit Button
          The Edit Button allows a user to modify or add information once authenticated and if the user has appropriate permissions.
        • Return Button (Study)
          The Return Button brings the user back to the Data from Papers page.
        • Sex
          Sex is defined at birth and can only be Male or Female. In some places in the NDA, we incorrectly used the data_element name of Gender. Users are encouraged to review definitions and not make assumptions based upon a data element name.
        • Data Use Limitations
          Data Use Limitations (DULs) describe the appropriate secondary use of a dataset and are based on the original informed consent of a research participant. NDA only accepts consent-based data use limitations defined by the NIH Office of Science Policy.
        • Permission Group
          Access to shared record-level data in NDA is provisioned at the level of a Permission Group. NDA Permission Groups consist of one or multiple NDA Collections that contain data with the same subject consents.
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